Medical microbiology and virology Books
Springer Nature Switzerland AG Immunoepidemiology
Book SynopsisThis textbook focuses on the nascent field of Immunoepidemiology that addresses how differences in immune responses among individuals affect the epidemiology of infectious diseases, cancer, hypersensitivity, and autoimmunity. The idea for the book originated from a course entitled “Immunology for Epidemiologists“ at the Yale School of Public Health. While many fine textbooks are available that address the immunological responses of individuals to pathogens, these provided very little information regarding how immunological variation among populations affects the epidemiology of disease. And yet, it has long been recognized that there is great immunologic diversity among people, which can have a profound effect on the epidemiology of disease. Careful review of the immunologic and epidemiologic literature revealed that there have been relatively few publications concerning immunoepidemiology and that no textbook is available on the subject. This textbook therefore aims to fill this void by providing a much-needed tool to comprehensively and efficiently teach immunoepidemiology. The book includes a section on the basic principles of immunology, and then applies them to particular examples of disease in human populations. The target audience for this text book are Masters of Public Health students. Others who should also find it of interest include PhD students in epidemiology, immunology, medical students, generalists, and specialists in immunology, infectious diseases, cancer, and rheumatology.Table of ContentsSection I. IntroductionChapter 1. Introduction to Immunology, Epidemiology, and ImmunoepidemiologyLinda Niccolai, Nancy H. Ruddle, and Peter J. KrauseChapter 2. Organization and Cells of the Immune SystemPaula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhDChapter 3. Innate Immunity: Recognition and Effector FunctionsPaula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhDChapter 4. Adaptive Immunity: Antigen Recognition by T and B LymphocytesPaula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhDChapter 5 Adaptive Immunity: Effector Functions, Regulation, and VaccinationPaula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhDChapter 6. Disorders of the Immune SystemPaula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhDChapter 7. Polymorphisms of Selected Components of the Innate and Adaptive Immune SystemsNancy H. Ruddle and Paula B. KavathasChapter 8. Immunoepidemiology of Immune DysfunctionEric Meffre, Peter J. Krause and Nancy H. RuddleChapter 9. Immunoepidemiology of Mycobacterium tuberculosisCamila D. Odio, Richard J. BucalaChapter 10. Host Immunity to Human immunodeficiency Virus InfectionElijah PaintsilChapter 11. Fungal ImmunoepidemiologyMarwan M. AzarChapter 12. Immunoepidemiology of Plasmodium falciparum MalariaAmy K. Bei, Sunil ParikhChapter 13. Immunoepidemiology of CancerXiaomei Ma, Rong WangChapter 14. Modeling Approaches Toward Understanding Infectious Disease TransmissionLaura A. Skrip, Jeffrey P. TownsendChapter 15. VaccinesDiane McMahon-PrattChapter 16. Immunotherapy for Infectious Diseases, Cancer, and AutoimmunityPeter J. Krause, Paula B. Kavathas, Nancy H. RuddleAppendixJane O'Bryan, Kara Fikrig, Peter J. Krause, Kate Nyhan
£59.99
Springer Nature Switzerland AG The End of an Antibiotic Era: Bacteria's Triumph
Book SynopsisIn this monograph, journalist Rinke van den Brink takes a closer look at the limitations and risks of today’s antibiotic use. Though all developed societies have grown accustomed to successfully treating bacterial infections with these wonder drugs, the author focuses on the increasing number of antibiotic-resistant infections. By examining recent mass outbreaks, readers will gain a better understanding of the global impact of antimicrobial resistance – one of the most serious public health threats today. Following this somewhat disquieting review of the status quo, interviews with a number of specialists provide an outlook on possible solutions. In a world that is more connected than ever, partnerships between different healthcare systems are becoming all the more important. Rinke van den Brink uses the example of a border-spanning collaboration between the Netherlands and Germany to demonstrate how effective lines of communication can be established. The book offers a wealth of useful background information for healthcare personnel. Not only does it share insights into the functional microbe-antibiotic relationship; it also discusses how clinics can effectively address outbreaks, helping readers to learn from past experiences and develop effective new strategies.Table of ContentsPreface (Prof. Dr. Alex W. Friedrich)Introduction In the beginning there was antibiotic resistance Human and economic costs Mega-outbreak at Maasstad Hospital A thin layer of faeces on everything you touch The beginning of the end The end in sight? Looking behind the figures The role of microbiology INTERREG projects: ‘Pathogens don’t recognise any borders’ Afterword
£26.59
Springer Nature Switzerland AG Molecular Typing in Bacterial Infections, Volume
Book SynopsisThis updated second edition of Molecular Typing in Bacterial Infections, presented in two volumes, covers both common and neglected bacterial pathogenic agents, highlighting the most effective methods for their identification and classification in the light of their specific epidemiology. New chapters have been included to add new species, as well as another view of how bacterial typing can be used. These books are valuable resources for the molecular typing of infectious disease agents encountered in both research and hospital clinical laboratory settings, as well as in culture collections and in the industry. Each of the 21 chapters provides an overview of specific molecular approaches to efficiently detect and type different bacterial pathogens. The chapters are grouped in five parts, covering respiratory and urogenital pathogens (Volume I), and gastrointestinal and healthcare-associated pathogens, as well as a new group of vector-borne and Biosafety level 3 pathogens including a description of typing methods used in the traditional microbiology laboratory in comparison to molecular methods of epidemiology (Volume II). Comprehensive and updated, Molecular Typing in Bacterial Infections provides state-of-the-art methods for accurate diagnosis and for the correct classification of different types which will prove to be critical in unravelling the transmission routes of human pathogens.Table of Contents1. Campylobacter Sophie J. Hedges and Frances M. Colles2. Clostridioides difficile Eliane de Oliveira Ferreira and Gerly Anne de Castro Brito3. CronobacterMarcelo L. L. Brandão and Stephan Forsythe4. Oral and Intestinal Bacteroidetes Marina C. Claros, Zaida C. Claros, Sareh Said Yekta-Michael, and Georg Conrads5. Vibrio choleraeThandavarayan Ramamurthy, Asish K. Mukhopadhyay, Bhabatosh Das, Ranjan K. Nandy, Ankur Mutreja, and G. Balakrish Nair6. Acinetobacter baumanniiDennis Nurjadi and Sébastien Boutin7. EnterococcusLúcia M. Teixeira, Adriana R. Faria, Stephanie S. R. Souza and Vânia Lúcia C. Merquior8. Pseudomonas aeruginosaJunyan Liu, Ruirui Xu, Zerong Lu and Zhenbo Xu9. StaphylococciJoAnn M. McClure and Kunyan Zhang10. BartonellaceaeJoaquim Ruiz, Cláudia Gomes and Maria J.Pons11. BrucellaRoland T. Ashford and Adrian M. Whatmore12. Coxiella burnetiiDimitrios Frangoulidis, Mathias C. Walter, Akinyemi M. Fasemore and Sally J. Cutler
£132.99
Springer Nature Switzerland AG Molecular Typing in Bacterial Infections, Volume
Book SynopsisThis updated second edition of Molecular Typing in Bacterial Infections, presented in two volumes, covers both common and neglected bacterial pathogenic agents, highlighting the most effective methods for their identification and classification in the light of their specific epidemiology. New chapters have been included to add new species, as well as another view of how bacterial typing can be used. These books are valuable resources for the molecular typing of infectious disease agents encountered in both research and hospital clinical laboratory settings, as well as in culture collections and in the industry. Each of the 21 chapters provides an overview of specific molecular approaches to efficiently detect and type different bacterial pathogens. The chapters are grouped in five parts, covering respiratory and urogenital pathogens (Volume I), and gastrointestinal and healthcare-associated pathogens, as well as a new group of vector-borne and Biosafety level 3 pathogens including a description of typing methods used in the traditional microbiology laboratory in comparison to molecular methods of epidemiology (Volume II). Comprehensive and updated, Molecular Typing in Bacterial Infections provides state-of-the-art methods for accurate diagnosis and for the correct classification of different types which will prove to be critical in unravelling the transmission routes of human pathogens.Table of Contents1. Campylobacter Sophie J. Hedges and Frances M. Colles2. Clostridioides difficile Eliane de Oliveira Ferreira and Gerly Anne de Castro Brito3. CronobacterMarcelo L. L. Brandão and Stephan Forsythe4. Oral and Intestinal Bacteroidetes Marina C. Claros, Zaida C. Claros, Sareh Said Yekta-Michael, and Georg Conrads5. Vibrio choleraeThandavarayan Ramamurthy, Asish K. Mukhopadhyay, Bhabatosh Das, Ranjan K. Nandy, Ankur Mutreja, and G. Balakrish Nair6. Acinetobacter baumanniiDennis Nurjadi and Sébastien Boutin7. EnterococcusLúcia M. Teixeira, Adriana R. Faria, Stephanie S. R. Souza and Vânia Lúcia C. Merquior8. Pseudomonas aeruginosaJunyan Liu, Ruirui Xu, Zerong Lu and Zhenbo Xu9. StaphylococciJoAnn M. McClure and Kunyan Zhang10. BartonellaceaeJoaquim Ruiz, Cláudia Gomes and Maria J.Pons11. BrucellaRoland T. Ashford and Adrian M. Whatmore12. Coxiella burnetiiDimitrios Frangoulidis, Mathias C. Walter, Akinyemi M. Fasemore and Sally J. Cutler
£132.99
Springer Nature Switzerland AG SARS-CoV-2 Spike Protein Convergent Evolution: Impact of Virus Variants on Efficacy of COVID-19 Therapeutics and Vaccines
Book SynopsisThis book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.Table of ContentsWhy the Spike protein is relevant for COVID19 therapeutics Whole genome mutation rates Phylogenetic systems Mechanism of immune escape: single nucleotide mutations, insertion/deletions, and recombination. Spike protein mutations detected in currently circulating strains. SARS-CoV-2 variants B.1.1.298 B.1.1.7 (alpha) B.1.351 (beta) B.1.1.28- and B.1.1.33-derived Brazilian variants (including gamma and zeta) B.1.525 (eta) B.1.526 (iota) B.1.427/B.1.429 (epsilon) B.1.617-derived variants (including kappa and delta) B.1.617.1 Delta VOC C.37 (lambda) P.3 (theta) Other variants under monitoring (VUM) Which strain will finally become dominant? SARS-CoV-2 variants characterization Predicting the functional consequences of mutations Efficacy of vaccines and monoclonal antibodies against SARS-CoV-2 variants Selective pressures exerted by antibody-based therapeutics
£54.99
Springer Infectious Diseases and Arthropods
£123.49
Wiley-VCH Verlag GmbH Mikrobiologie für Dummies
Book SynopsisAuch wenn es beim Thema Mikrobiologie nur um winzig kleine Lebewesen geht hat es das Thema doch in sich. Denn Ihre geringe Größe machen Mikroorganismen durch ihre Anzahl wett. Wussten Sie beispielsweise, dass auf und im menschlichen Körper mehr Bakterien leben als er Zellen hat? Und viele davon sind für unser Überleben zwingend erforderlich. In diesem Buch lernen Sie, wie diese Einzeller aufgebaut sind, in welche Gruppen man sie einteilen kann und welche typischen Eigenschaften zu dieser Klassifizierung führen. Egal ob Eukaryoten, Prokaryoten, Viren oder Pilze Sie finden zu allem die wichtigsten Infos. Natürlich beschreibt die Autorin auch wie Mikroorganismen Krankheiten verursachen, wie man sich dagegen wappnen kann und welche bedeutsame Rolle die Winzlinge in Forschung und Medizin spielen. Sie werden sich wundern!Table of ContentsEinleitung 17 Über dieses Buch 17 Törichte Annahmen über den Leser 18 Symbole in diesem Buch 18 Wie Sie dieses Buch für sich nutzen können 19 Teil I: Einführung in die Mikrobiologie 21 Kapitel 1 Mensch und Mikrobiologie 23 Wozu brauchen wir die Mikrobiologie? 23 Ein Blick auf die Welt der Mikroorganismen 24 Mikrobiologie aus verschiedenen Blickwinkeln 25 Kapitel 2 Mikrobiologie: die neue Wissenschaft 27 Aberglaube und Fehleinschätzungen 28 Die Entdeckung der Mikroben 28 Der Mythos der Urzeugung wurde entlarvt 29 Gesundheit durch Hygiene, Antibiotika und Impfungen 30 Andere wichtige Entdeckungen der Mikrobiologie 32 Die Zukunft der Mikrobiologie 32 Viel Raum nach oben 33 Neue Herausforderungen meistern 33 Kapitel 3 Mikroorganismen: sind überall und können (fast) alles 37 Die Diversität mikrobieller Lebensräume 38 Die metabolische Vielfalt 40 Woher stammt die Energie? 40 Woher stammt der Kohlenstoff? 41 Enzymatische Vielfalt 41 Sekundärstoffwechsel 42 Wenn Wirt und Mikroorganismus aufeinandertreffen 42 Teil II: Mikrobielles Leben unter der Lupe 45 Kapitel 4 Grundlagen der Zellstruktur und Funktion 47 Zellform ist Ansichtssache 47 Leben im Mikromaßstab 48 Die Zelle im Überblick 50 Innere Membran, Zellwand und äußere Membran 50 Struktur und Funktion der inneren Membran 51 Die bakterielle Zellwand 53 Die äußere Membran gramnegativer Zellen 55 Die Zellwand der Archaeen 56 Weitere wichtige Zellbestandteile 56 Zellstrukturen der Prokaryoten 56 Aus eins mach zwei: Zellteilung 58 Transportsysteme: rein wie raus 59 Passiver Transport: immer entlang des Gradienten 59 Aktiver Transport: Energie ist gefragt 60 Aufräumen ist angesagt: Effluxpumpen 61 Wir kommen rum: Fortbewegung 61 Kapitel 5 Einblick in den Stoffwechsel 63 Mit Enzymen läuft’s schneller 63 Ohne Energie kein Leben: Oxidation und Reduktion 65 Fast wie Billard – Elektronenübertragung 66 Deals mit energiereichen Verbindungen 68 Wenn die Zeiten schlechter werden: Energiespeicher 68 Kurz und klein im Katabolismus 69 Nicht schwer zu verdauen – die Glykolyse 70 Schritt für Schritt weiter: die Atmung 71 Bewegung im Spiel: die protonenmotorische Kraft 72 Es geht rund: der Citratzyklus 74 Sehr aufbauend – der Anabolismus 75 Die Synthese von Aminosäuren 75 Die Synthese von Nukleinsäuren 76 Zucker- und Polysaccharidsynthese 76 Fettsäure- und Lipidsynthese 78 Kapitel 6 Genetik der Mikroorganismen 81 Die Organisation des genetischen Materials 81 Ein Kochbuch fürs Leben: die DNA 82 Perfekt outgesourct: die Plasmide 84 Aus eins mach zwei: DNA-Replikation 84 Von der DNA zum Protein 89 Transkription: Synthese der mRNA 89 Transfer- und ribosomale RNAs 90 Translation: Ein Protein entsteht 90 Regulation von Proteinsynthese und Proteinaktivität 95 Transkriptionsregulation 95 Regulation auf der Ebene der Proteinaktivität 97 Kein Fortschritt ohne Veränderung 97 Nobody is perfect – die Punktmutationen 98 Umbau ist angesagt – nicht immer zum Vorteil 99 Transformation und Konjugation 100 Viren im Spiel: die Transduktion 101 Wenn Gene springen: die Transposition 101 Kapitel 7 Mikrobielles Wachstum messen 103 Optimale Wachstumsbedingungen identifizieren 103 Physikalische Anforderungen 103 Mikroorganismen im Labor kultivieren 106 Mikroorganismen im Blickfeld 108 Zählen im Mikrobenmaßstab 108 Ziemlich bunt: die Färbeverfahren 110 Zellteilungsrate und Zellzunahme beurteilen 112 Mal so, mal so: die Zellteilung 112 Aus eins mach viele: die Wachstumsphase 112 Hemmung des mikrobiellen Wachstums 114 Physikalische Methoden zur Entkeimung 114 Desinfektionsmittel 115 Teil III: Die Evolution des Mikrokosmos 117 Kapitel 8 Evolution der Mikroorganismen 119 Erste Organismen auf der Bühne des Lebens 119 Der Ursprung des Lebens 119 Diversifikation der frühen Prokaryoten 120 Der Einfluss von Prokaryoten auf die frühe Erde 121 Untermieter gesucht: die Endosymbiose 122 Was ist Evolution? 124 Das Evolutionsgeschehen untersuchen 126 Geeignete Markergene auswählen 127 Die Richtung des Gentransfers in Prokaryoten 128 Klassifikation und Taxonomie von Mikroorganismen 128 Weit verzweigt - der Baum des Lebens 130 Kapitel 9 Energiegewinnung und CO2-Fixierung 133 Die Selbstversorger: autotrophe Organismen 133 Fixierung von anorganischem Kohlenstoff 134 Die Energie des Lichts nutzen 137 Lichternte mit Chlorophyllen und Bakteriochlorophyllen 138 Akzessorische Pigmente: Carotinoide und Phycobiline 141 Sauerstoff erzeugen oder nicht: oxygene und anoxygene Photosynthese 141 Energie aus anorganischen Verbindungen: Chemolithotrophie 146 Wasserstoff nutzen 146 Elektronen aus dem Schwefel 147 Starke Sache: Eisen pumpen 148 Nitrat- und Ammoniakoxidation 148 Kapitel 10 Gärung und Atmung im Vergleich 151 Lebensstile der Reichen und Fakultativen 151 Ein Überblick zum Einstieg 153 Einmal tief durchatmen: die Respiration 155 Wie im Kreisverkehr: der Citratzyklus 156 Immer schön treppab: die Elektronentransportkette 157 Anaerobe Atmung 158 Nitrat und Denitrifikation 159 Sulfat- und Schwefelreduktion 160 Acetogenese und Methanogenese 160 Abbau von Kohlenwasserstoffen und anderen Verbindungen 160 Bunte Vielfalt: die Gärungstypen 161 Kapitel 11 Mikrobielle Lebensräume 165 Was genau ist ein Habitat? 166 Nährstoffkreisläufe verstehen 167 Der Kohlenstoffkreislauf 167 Der Stickstoffkreislauf 169 Der Schwefelkreislauf 171 Phosphorkreisläufe im Ozean 172 Mikroorganismen in Interaktion 172 Kommunikation durch Quorum Sensing 173 Das Leben im Biofilm 173 Mikrobielle Matten 174 Mikroorganismen in aquatischen und terrestrischen Lebensräumen 175 Aquatische Mikroorganismen 175 Oxygene versus anoxygene Phototrophe 176 Der Boden lebt 176 Mit Pflanzen und Tieren auskommen 177 In Interaktion mit Pflanzen 178 Mikroorganismen in Tieren 179 Symbiosen mit Insekten 181 Symbiosen mit Meeresbewohnern 181 Leben unter extremen Bedingungen 182 Mikroorganismen an unerwarteten Orten 183 Teil IV: Mikroben in Hülle und Fülle 185 Kapitel 12 Die Prokaryoten im Überblick 187 Prokaryoten, Teil 1: Die Bakterien 188 Die gramnegativen Bakterien: Proteobakterien 188 Heterotrophe Lebensweise 190 Interessante Formen und Lebenszyklen 191 Weitere gramnegative Bakterien 193 Die grampositiven Bakterien 195 Prokaryoten, Teil 2: Die Archaeen 197 Manche mögen‘s (sehr) heiß: extrem thermophile Archaeen 199 Mehr als sauer: extrem acidophile Archaeen 200 Supersalzig: extreme Halophile 201 Mesophile Archaeen 202 Kapitel 13 Bühne frei für die Eukaryoten 203 Pilze 203 Mal so, mal so – die Physiologie der Pilze 204 Ein kleiner Eindruck von der Pilzvielfalt 206 Interaktion mit Pflanzenwurzeln 208 Die Ascomyceten (Schlauchpilze) 209 Die Basidiomyceten (Ständerpilze) 210 Prosperierende Vielfalt: die Protisten 211 Die Apicomplexa (Sporozoen) 211 Pflanzenpathogene Peronosporomyzeten (Eipilze) 213 Die Mikro-Jäger: Ciliaten und Amöben 214 Begegnung mit den Algen 216 Kapitel 14 Die Welt der Viren 221 Die Zelle fest im Griff der Viren 221 Sehr spartanisch: der Aufbau der Viren 221 Im Schnelldurchgang: die Replikation der Viren 223 Von Kopf bis Schwanz: Bakteriophagen 225 Die Viren der Eukaryoten 229 Viren, die tierische Zellen infizieren 229 Pflanzenviren auf der Spur 232 Viroide 233 Kein leichtes Opfer: wie Wirtszellen sich wehren 234 Restriktionsenzyme 234 Das CRISPR/Cas-System 235 Funkstille für RNA-Viren: RNAi 236 Teil V: Mikroorganismen und menschliche Gesundheit 237 Kapitel 15 Mikroben als Krankheitserreger 239 Bollwerk gegen Pathogene: die Immunantwort 239 Infektionsbarrieren aufbauen 240 Gleich die rote Fahne hissen: Entzündungen 240 Erst mal die Stellung halten: die angeborene Immunantwort 241 Das adaptive Immunsystem rückt aus 242 Antikörper in Aktion 244 Antimikrobielle therapeutische Wirkstoffe 246 Grundlegende Eigenschaften der Antibiotika 246 Ziele der Zerstörung 248 Mechanismen der Antibiotikaresistenz 249 Dringend gesucht: neue Antibiotika 251 Fahnden nach den »Superbugs« 252 Vancomycin-resistenten Enterokokken einen Schritt voraus sein 253 Kampf gegen Methicillin-resistente Staphylococcus aureus 253 Der Konkurrenz unterlegen: Clostridioides difficile 255 Beta-Lactamasen mit erweitertem Spektrum 255 Präbiotika und Probiotika 256 Antivirale Medikamente 257 Kapitel 16 Mikroben im Einsatz: die Biotechnologie 259 Rekombinante DNA-Technologie 259 Welche Gene suche ich? 260 Warum Plasmide so nützlich sind 263 Schneiden mit Restriktionsenzymen 264 Mikroorganismen dazu bringen, DNA aufzunehmen 266 Promotoren zur Expressionssteigerung 268 Von der DNA zum Protein: Expressionsvektoren 268 Origami mit Proteinen: die korrekte Faltung 269 Wenn fremde Gene lästig sind 270 Klonierung großer DNA-Konstrukte mit zahlreichen Genen 271 Therapien besser, schneller und billiger machen 273 Noch Raum nach oben: Antibiotika verbessern 273 Impfstoffe entwickeln 274 Mikroorganismen industriell nutzen 274 Mikrobiell produzierte Pflanzenschutzmittel 275 Mikrobiell produzierte Biokraftstoffe 276 Bioleaching von Metallen 276 Umweltschutz mit Mikroorganismen 277 Kapitel 17 Der Kampf gegen Infektionserreger 279 Gesundheitsschutz in der Gesellschaft: Epidemiologie 279 Wer ist infiziert und warum? 279 Ausbrüche untersuchen 280 Wo steckt der Erreger? 281 Der Weg von Wirt zu Wirt 281 Den Ausbruch unter Kontrolle halten 282 Diagnostik mikrobieller Pathogene 283 Charakterisierung anhand der Morphologie 283 Nachweis mit biochemischen Verfahren 284 Diagnostik mit einer Phagentypisierung 286 Mit Serologie punkten 287 Sensitivität gegenüber Antibiotika testen 288 Infektionserkrankungen eindämmen 289 Wie Impfstoffe wirken 290 Mehr oder weniger sicher: Arten von Impfstoffen 291 Teil VI: Neue Herausforderungen meistern 293 Kapitel 18 Mikrobielle Ökosysteme im Fokus 295 Untersuchung mikrobieller Gemeinschaften 295 Aus der Ökologie entlehnt 295 Warum mikrobielle Gemeinschaften anders sind 296 Methoden der mikrobiellen Ökologie 296 Mit Anreicherung locken 296 Fluoreszenzfarbstoffe in der Mikroskopie 297 Messung der mikrobiellen Aktivität 299 Artbestimmung mit Markergenen 299 Es geht ans Eingemachte: Sequenzierung & Co. 300 Genomsequenzierung 300 Vom Einzelgenom zum Metagenom 302 Mikrobielle Transkriptome lesen 303 Es geht noch weiter: Proteomik und Metabolomik 304 Die (mikrobielle) Spitze des Eisbergs 305 Kapitel 19 Synthetische Biochemie 307 Regulation der Genexpression: das lac-Operon 308 Nicht ganz so dicht … 309 Ein gutes System optimieren 309 Genetische Netzwerke entwickeln 312 Von einem Zustand in den anderen wechseln 312 Oszillieren zwischen Zuständen 313 Die Toolbox des synthetischen Biologen 315 Module für den Eigenbau 315 Teilnahme am iGEM-Wettbewerb 315 Teil VII: Der Top Ten-Teil 317 Kapitel 20 (Fast) zehn gefährliche Krankheiten durch Mikroben 319 Ebola 320 Milzbrand 320 Grippe 321 Tuberkulose 321 HIV 322 Cholera 322 Pocken 323 Primäre Amöben-Menigoenzephalitis 323 Neue Gefahren im Anmarsch 324 Kapitel 21 Zehn wichtige Anwendungen für Mikroorganismen 325 Bereicherung des Speiseplans 325 Biodüngen mit Hülsenfrüchten 326 Bier, Wein und Schnaps produzieren 326 Insektenschädlinge töten 326 Reinigung und Klärung von Abwasser 327 Beitrag zur Medizin und Schönheit 327 Starthilfe für Ihr Aquarium 328 Biobasierte Kunststoffe 328 Kompostierbare Abfälle 329 Die Balance des Körpers erhalten 329 Stichwortverzeichnis 331
£999.99
Wiley-VCH Verlag GmbH Medizinische Mikrobiologie für Dummies
Book SynopsisKokken, Stäbchen, Pilze, Viren, Prionen, Parasiten und Co. ? die Medizinische Mikrobiologie ist komplex und vielfältig. Aber keine Sorge, Ralf-Peter Vonberg und Christina Haese führen Sie Schritt für Schritt in die mikrobiologische Welt ein und erklären Ihnen alles, was Sie über pathogene Mikroorganismen und deren Bekämpfung wissen müssen. Dabei erläutern sie klar strukturiert das Wichtigste über Prävention, Diagnose und Behandlung von Infektionskrankheiten und richten sich dabei nach dem IMPP-Gegenstandskatalog.Table of ContentsÜber die Autoren 7 Einleitung 23 Teil I: Einführung 27 Kapitel 1: Infektionslehre, Epidemiologie und Hygiene – ein paar Grundlagen 29 Teil II: Bakteriologie 65 Kapitel 2: Grundlagen der Bakteriologie 67 Kapitel 3: Grampositive und gramnegative Kokken 71 Kapitel 4: Gramnegative Stäbchen 89 Kapitel 5: Grampositive aerobe Stäbchen 117 Kapitel 6: Anaerobe Bakterien 125 Kapitel 7: Säurefeste Stäbchen 137 Kapitel 8: Spirochäten, Intrazelluläre, Zellwandlose und »Partyreste« 145 Kapitel 9: Praktische Bakteriologie 163 Teil III: Virologie 197 Kapitel 10: Einführung in die Virologie – seltsame Gestalten 199 Kapitel 11: Retro- und Herpesviren – zwei unterschiedliche Familien 215 Kapitel 12: Virale Drüseninfektionen 235 Kapitel 13: Gastrointestinale und urogenitale Virusinfektionen – die inneren Rohrleitungen 251 Kapitel 14: Atemwegsinfekte – Husten, Schnupfen, Heiserkeit 259 Kapitel 15: Infektionen im Kopfbereich – Auge, Ohr, Gehirn 271 Kapitel 16: Viruserkrankungen mit Hauterscheinungen – sieht man doch! 281 Kapitel 17: Virales hämorrhagisches Fieber – Schrecken der Tropen 295 Kapitel 18: Virale Embryo- und Fetopathien, onkogene und transplantationsmedizinisch relevante Viren 305 Kapitel 19: Die »Basics« der Virusdiagnostik 315 Teil IV: Mykologie 323 Kapitel 20: Mykologie – Pilze in Theorie und Praxis 325 Teil V: Parasitologie 351 Kapitel 21: Parasitologie – kleine Tiere, großer Zoo 353 Teil VI: Serologie 387 Kapitel 22: Serologische Methoden – einfach, aber genial 389 Teil VII: Antiinfektive Therapie 409 Kapitel 23: Grundlagen der antiinfektiven Therapie 411 Kapitel 24: Antibiotika 417 Kapitel 25: Antimykotische Therapie 439 Kapitel 26: Antiparasitäre Therapie 443 Kapitel 27: Die Therapie von Viruserkrankungen 447 Teil VIII: Der Top- Ten- Teil 455 Kapitel 28: Wissenschaft, Literatur, Kunst und mehr 457 Abbildungsverzeichnis 467 Stichwortverzeichnis 477
£999.99
£32.20
£27.89
Springer MRI/CT and Pathology in Head and Neck Tumors: A Correlative Study
Book Synopsistic knowledge, a multidisciplinary approach is indis Over the past 60 years, radiology has progressively uncovered the human body. At first a fleshless skele pensable: clinicians, radiologists, surgeons, radio therapists, and pathologists must all contribute their ton for global study, the body then appeared in slices, until with present techniques its smallest respective inputs for every patient referred. More over, experience is acquired through knowledge of structures are revealed. The physician at the com cases whose diagnosis is certain, and with which new puter console is constantly amazed at the never ending series of organ sections and their mUltiple cases can be compared. In this way a data base is created, whether in the physician'S memory or in images arising through manipulation of the signal. Cerebral convolutions, orbital content, bone mar that of the computer, which is helpful in making row, the face and all its bones can now be made visi diagnoses. ble without any danger to the patient. A lesion can be detected, located and identified; it can be ob Dr.Trade Review`Every radiology library should have this book and every radiologist and radiology resident should read it.' S. Gebarski in Journal of Roentgenology, July 1990Table of ContentsOne: Introduction.- Two: Technical Considerations.- 2.0 Summary.- 2.1 The nuclear magnetic resonance (NMR) phenomenon.- 2.2 Relaxation and magnetic relaxation times.- 2.3 Location of magnetic resonance signal.- 2.4 Pulse sequences.- 2.5 Image contrast.- 2.6 Signal-to-noise ratio (S/N), spatial resolution and imaging time.- 2.7 Image acquisition time.- 2.8 MR signal characteristics of soft tissues.- References for Chapter Two.- Three: Case Presentations.- A. Orbital and paraorbital regions.- Case 1. Orbital metastasis of renal cell carcinoma.- Case 2. Squamous cell carcinoma of the fronto-orbital region with invasion of the orbit, frontal bone and frontal sinus.- B. Paranasal sinuses, including nasal cavities.- Case 3. Rhabdomyosarcoma of the ethmoid and maxillary sinuses.- Case 4. Leiomyosarcoma of the antroethmoidal sinuses.- Case 5. Fibrous dysplasia of the sphenoethmoidal region.- Case 6. Adenocarcinoma of the nasal cavities and ethmoid sinuses.- Case 7. Chondrosarcoma of the sphenoid sinus.- Case 8. Squamous cell carcinoma of the nasopharynx, paranasopharyngeal space, and maxillary antrum.- C. Temporal bone/base of skull.- Case 9. Squamous cell carcinoma of the external auditory canal.- Case 10. Glomus tympanicum tumor with extension into the upper part of jugular fossa.- Case 11. Glomus jugulare tumor.- Case 12. Multiple myeloma presenting as a solitary lesion of the base of skull.- Case 13. Schwannoma of the jugular foramen with extension into the cerebellopontine angle, petrous bone, and neck.- Case 14. Recurrent cholesterol cyst of the base of skull.- D. Salivary glands.- Case 15. Mixed tumor of the left parotid gland.- Case 16. Warthin’s tumor of the right parotid gland and metastatic squamous cell carcinoma of the right neck.- Case 17. Warthin’s tumor of the left parotid gland.- Case 18. Oncocytoma of the left parotid gland.- Case 19. Focal carcinoma in pleomorphic adenoma of the left parotid gland.- Case 20. Adenocarcinoma of the right parotid gland.- Case 21. Lipoma of the right parotid gland.- E. Nasopharynx.- Case 22. Nasopharyngeal carcinoma with bilateral metastatic lymph nodes.- Case 23. Advanced carcinoma of the nasopharynx.- F Oropharynx and oral cavity.- Case 24. Squamous cell carcinoma of the left retromolar trigone.- Case 25. Squamous cell carcinoma of the right tongue.- Case 26. Squamous cell carcinoma of the base of the tongue.- G. Larynx.- Case 27. Oat cell carcinoma of the epiglottis.- Case 28. Extensive supraglottic squamous cell carcinoma.- Case 29. Squamous cell carcinoma of the right pyriform fossa.- H. Hypopharynx.- Case 30. Squamous cell carcinoma of the hypopharynx.- Case 31. Carcinoma of the hypopharynx with huge right neck mass.- I. Parapharyngeal space.- Case 32. Paraganglioma of the glomus vagale in the neck.- Case 33. Mixed tumor of the left parapharyngeal space.- J. Neck.- Case 34. Branchial cleft cyst of the right neck.- Case 35. Cystic-appearing metastatic lymph node in the right neck.- References for Chapter Three.- Four: Mri Strategy in Evaluating Head and Neck Tumors.- 4.1 Introduction.- 4.2 Optimum MR imaging parameters.- 4.3 MR and head and neck imaging, according to anatomic areas.- 4.3.1 Orbital regions.- 4.3.2 Temporal bone/base of skull.- 4.3.3 Salivary glands — Parapharyngeal space.- 4.3.4 Paranasal sinuses.- 4.3.5 Nasopharynx.- 4.3.6 Oropharynx and oral cavity.- 4.3.7 Larynx, hypopharynx, and neck.- 4.4 Gadolinium-DTPA for MR imaging in the head and neck.- 4.5 Unresolved problems.- References for Chapter Four.- Five: Conclusions.
£44.99
Springer Acute Virus Infections of Poultry: A Seminar in the CEC Agricultural Research Programme, held in Brussels, June 13–14, 1985
Book SynopsisThis book is based on the proceedings of a seminar on acute viral in fections of poultry, which was held in Brussels on 13-14 June 1985. The aim of the seminar, which was sponsored by the CEC, was to gather infor mation on those infections of immediate or increasing importance. It is hoped that dissemination of this information will make it easier to har monize diagnostic and control measures throughout the member states of the EEC. Several points emerge from recent outbreaks of highly pathogenic avian influenza. In view of the apparent change in pathogenicity of the virus involved in the outbreak in the USA, infections of domestic poultry, particularly with H5 and H7 sub-types, should be regarded as a potential threat, even if the viruses involved are of low pathogenicity. The reasons for the amount of lateral spread which occurred in the USA outbreak are still not clear, and it can not be assumed that future outbreaks of highly pathogenic avian influenza will tend to be self-limiting, as in the past. The importance of denying access of wild birds, particularly water fowl, to domestic poultry needs to be re-emphasised. Lastly, there appears to be increasing support for a combination of slaughter and ring vaccination to control future outbreaks of spreading avian influenza.Table of ContentsA Lethal Outbreak of H5N2 Influenza in Poultry in the USA: Virus Characterization and Host Range.- The Control and Epidemiology of an Influenza A Outbreak in Ireland.- Current Situation of Avian Influenza in Italy and Approaches to its Control.- Avian Influenza: Diagnosis and Vaccination.- Experimental Vaccination of Chickens Against Avian Influenza Subtype H5 With an Inactivated Oil Emulsion Vaccine.- The Classification, Host Range and Distribution of Avian Paramyxoviruses.- Paramyxovirus Type 1 Infection in Pigeons.- Vaccination of Pigeons With Live and Inactivated Vaccines Against Paramyxovirus 1 Infection.- Avian Paramyxovirus Type 1 Infections in Pigeons - Spread to Domestic Poultry in Great Britain in 1984.- Recent Advances in Paramyxovirus Infection of Turkeys in France.- The Diagnosis and Control of Infectious Bronchitis Variant Infections.- A New Pathogenic Avian Infectious Bronchitis Virus Isolated in France.- Antigenic Differentiation of Avian Bronchitis Virus Variant Strains Employing Monoclonal Antibodies.- Efficiency of Oil Adjuvanted Infectious Bronchitis Vaccines.- Evaluation of Vaccination Experiments in Broiler Breeders and Layers With Live Virus and Formalin Inactivated Oil Emulsion Infectious Bronchitis Vaccines.- Preliminary Results With a Combined Inactivated Newcastle Disease and Infectious Bronchitis (Variant Strain) Vaccine in Laying Hens.- An Enterotropic Avian Infectious Bronchitis Virus.- Runting in Broilers.- Runting Syndrome in Broiler Chickens. Experimental Reproduction Studies.- Findings in History and Etiology of the Stunting Syndrome in the USA.- Recent Advances in Enterovirus Infections of Birds.- Avian Infectious Anaemia Caused by Chicken Anaemia Agent (CAA).- Recent Advances in Duck Viral Hepatitis.- Duck Hepatitis Type 2 Associated With an Astrovirus.- Dual Infections of Ducks With Derzsy’s Disease and Eds (A-127) Viruses.- Diagnosis and Control of Parvovirus Infection of Geese (Derzsy’s Disease).
£44.99
Ediciones UC Del gusano cósmico al cerebro del pulpo
£15.75
Springer Malaria Control and Elimination in China
Book SynopsisChapter 1 Case Study on Malaria Surveillance and Response: Implementation of the 1-3-7 Strategy in Jiangsu Province, China.- Chapter 2 Malaria along international border in Yunnan of China, 2003-2020: a case study of border malaria control and elimination.- Chapter 3 The Three-Layer Strategy (TLS) Promoted Malaria Elimination Among Forest Goers in Hainan Province.- Chapter 4 How to Ensure the Effect of Mass Drug Administration (MDA) on the Control of Plasmodium vivax Malaria.- Chapter 5 Bacterial larvicides contribute to the control of malaria outbreaks.- Chapter 6 Discovery History of Artemisinin.- Chapter 7: International Promotion of Artemisinin-based Combination Therapies.
£151.99
Independent Publisher A Comprehensive Literature Resource Package on Insect Biology
£26.59
Amazon Digital Services LLC - Kdp Bioluminiscencia
£999.99
Independently Published Rotifers Anfängerhandbuch
£15.22
Amazon Digital Services LLC - Kdp Investigación Sobre la Biología del Envejecimiento y la Regeneración Celular
£999.99
Amazon Digital Services LLC - Kdp Los Pequeños Arquitectos de la vida
£999.99
Amazon Digital Services LLC - Kdp Simbiosis
£999.99
Amazon Digital Services LLC - Kdp Symbiose
£999.99
Amazon Digital Services LLC - Kdp Virología
£999.99
Amazon Digital Services LLC - Kdp Virologie
£999.99
Taylor & Francis Ltd Tumor Antigens Recognized by T Cells and
Book SynopsisRecent progress in fundamental tumor immunology has led to immunotherapy trials in patients with solid tumors and hematological malignancies. In the past, immunotherapy approaches were primarily based on enhancement of tumor immunity with cytokines and adjuvant therapy, without knowledge of relevant tumor antigens. The discovery of tumor antigens capable of eliciting immune responses has now resulted in the development of antigen-specific immunotherapy strategies. Vaccination with defined peptide epitopes, purified proteins, cell components, and whole cells expressing defined tumor antigens provides an opportunity to measure antigen-specific immune responses in vaccinated patients, and to correlate immunity with clinical outcome.Tumor Antigens Recognized by T Cells and Antibodies provides a comprehensive overview of the molecular nature of tumor antigens that can be recognized by antibodies, helper T lymphocytes and cytotoxic T lymphocytes. Novel strategies to enhance ineffectiTable of ContentsTumor Antigens Recognized by Antibodies. Human Tumor Antigens Recognized by Antibodies (SEREX). Antibodies to Tumor Oncoproteins in Cancer Patients. Antibody and CTL Responses to the NY-ESO Antigen. Tumor Antigens Recognized by CD4+ T Cells (predominantly TH1). Melanoma Antigens Recognized by CD4+ T Cells. Mouse Models in the Recognition of Tumor Antigens. Antigens of the MAGE Family Recognized by CD4+ T Cells. Tumor antigens Recognized by CD8 T Cells. Melanoma Antigens Recognized by CD8 T Cells. Squamous Cells and Adeno Cancer Antigens Recognized by T Cells. Heat/Shock Proteins and Tumor Antigens. The Wilms Tumor Antigens as CTL Target. Ex vivo and in situ Tetramer Analysis of CTL Responses to Tumors. Altered Peptide Ligands of Tumor T Cell Epitopes: Implications for More Effective Vaccine Therapy in Human Neoplasia.
£166.25
Elsevier Health Sciences Sterilization Disinfection Control
Book Synopsis
£37.04
Elsevier Health Sciences Clinical Cases in Microbiology and Infectious
Book Synopsis
£37.04
Taylor & Francis Inc Microbiological Assay For Pharmaceutical Analysis
Book SynopsisA user-friendly guide for the evaluation of microbiological assays, Microbiological Assay for Pharmaceutical Analysis: A Rational Approach provides a lucid explanation of the sources of error in microbiological assay and helps analysts choose efficient assay designs that will minimize those sources of error. Beginning with a review of the theoretical basis for the quantitative aspects, the author discusses microbiological assay as a branch of pharmaceutical analysis and distinguishes it from biological assay in general. He draws attention to the microbiological aspects that may not be so obvious to the chemical analyst and to the analytical aspects that may not be so obvious to the microbiologist. The book contains detailed evaluations of assays that illustrate typical experimental designs and addresses how to present a realistic assessment of the best potency estimate from a series of assays. Although there are other valuable books available in this area, they do not address Table of ContentsMicrobiological Assay in Perspective. The Agar Diffusion Assay - Its Quantitative Basis. The Theory and Practice of Tube Assays for Growth Promoting Substances. The Theory and Practice of Tube Assays for Growth Inhibiting Substances. What Do We Want of an Assay? How Do We Attain Our Goal? General Practical Aspects of Microbiological Assays. Standard Reference Materials. Parallel Lines Assays - Some Designs and Their Evaluation. Slope Ratio Assays, Some Designs and Their Evaluation. Choice of Experimental Design. Concluding Thoughts.
£356.25
Springer London Diseases in the Homosexual Male The Bloomsbury Series in Clinical Science
Book Synopsis1 Male Homosexuality: Cultural Perspectives.- 2 Bacterial Infections.- 3 Viral Infections.- 4 Protozoal Infections.- 5 Hepatitis.- 6 Genital Warts.- 7 Syphilis.- 8 AIDS: Epidemiology and Clinical Aspects.- 9 AIDS: Counselling and Support.- 1.- 2.- 10 AIDS and Homosexuality in Britain: A Historical Perspective.Table of Contents1 Male Homosexuality: Cultural Perspectives.- 2 Bacterial Infections.- 3 Viral Infections.- 4 Protozoal Infections.- 5 Hepatitis.- 6 Genital Warts.- 7 Syphilis.- 8 AIDS: Epidemiology and Clinical Aspects.- 9 AIDS: Counselling and Support.- 1.- 2.- 10 AIDS and Homosexuality in Britain: A Historical Perspective.
£42.74
Springer Us Regulation of Gene Expression in Animal Viruses Nato Science Series A Closed 240
Book SynopsisStructure of a human rhinovirus complexed with its receptor molecule.- Cascade regulation of vaccinia virus gene expression.- Regulation of alpha and gamma gene expression in cells infected with herpes simplex viruses.- Transcriptional activation by the adenovirus E1A proteins.- Mechanisms regulating nucleocapsid formation of the hepatitis B viruses.- Transcriptional activation by the hepatitis B virus X protein.- Regulation of human immunodeficiency virus structural protein expression and virion formation.- Transcription factors of the ETS family: The example of C-ETS1.- Infectious influenza viruses from cDNA-derived RNA: reverse genetics.- Structure and function of the vesicular stomatitis virus RNA-dependent RNA polymerase.- RNA Synthesis and mRNA Editing in Paramyxovirus Infections.- Antigenic variation of human respiratory syncytial virus G Glycoprotein: Genetic mechanisms and evolutionary significance.- Translation regulation by reovirus structural proteins.- The regulation of Coronavirus gene expression.- Interaction of initiation factors and capsid protein with the cap structure of chimaeric MRNAS containing the 5? untranslated regions of the RNAS of semliki forest virus.- Aspects of the molecular biology of poliovirus replication.- 3CD Cleavage of the poliovirus P1 precursor: a model for complex proteinase/substrate interactions.- Studies on the mechanism of internal initiation of translation on poliovirus RNA.- Picornavirus Variation.- Modification of membrane permeability by animal viruses.- Miguel Angel Sanz and Ma José Ayala, Poliovirus neurovirulence and its attenuation.Table of ContentsStructure of a Human Rhinovirus Complexed with its Receptor Molecule; N.H. Olson, et al. Cascade Regulation of Vaccinia Virus Gene Expression; B. Moss. Transcriptional Activation by the Adenovirus E1A Proteins; B.A. Lewis, T. Shenk. Mechanisms Regulating Nucleocapsid Formation of the Hepatitis B Viruses; R. Bartenschlager, H. Schaller. Transcriptional Activation by the Hepatitis B Virus X Protein; R. Lucito, R.J. Schneider. Transcription Factors of the ETS Family; K. Macleod, et al. Structure and Function of the Vesicular Stomatitis Virus RNA-Dependent RNA Polymerase; S. Barik, et al. RNA Synthesis and mRNA Editing in Paramyxovirus Infections; J. Curran, et al. Translational Regulation by Reovirus Structural Proteins; A.J. Shatkin, et al. The Regulation of Coronavirus Gene Expression; S.G. Siddell. Aspects of the Molecular Biology of Poliovirus Replication; J. Harber, E. Wimmer. 9 additional articles. Index.
£46.74
Taylor & Francis Inc Foodborne Viral Pathogens
Book SynopsisViral transmission through contaminated food and water claims hundreds of thousands of lives every year, particularly affecting children in developing nations. Foodborne viral pathogens are associated with gastroenteritis and hepatitis, causing widespread epidemics that affect all populations and demographics worldwide. Foodborne Viral Pathogens comprehensively covers the predominant etiological viral agents of foodborne disease, including norovirus, hepatitis A virus, hepatitis E virus, astrovirus, sapovirus and rotavirus, and several emerging viruses and prions. By improving food safety awareness and viral detection, and through promotion of global food safety standards, our ability to cope with and control foodborne disease will be enhanced. Foodborne Viral Pathogens includes a detailed review of the molecular biology, potential vaccines, and available antiviral treatments of all major foodborne viral pathogens and prions. WritteTable of ContentsNEW TECHNOLOGIES, RISK ASSESSMENT AND STRATEGIES FOR CONTROL OF VIRAL FOODBORNE ILLNESS. Introduction. Next Generation Sequencing, What Has It Told Us So Far? New Technologies for Viral Diagnosis and Detection, Using Enteroviruses as an Example. Measuring and Minimizing Health Impacts of Foodborne Viruses: A Targeting Tool for Risk Reduction. Strategies for Control of Food- and Waterborne Viruses. IMPORTANT AGENTS IN FOODBORNE VIRAL INFECTIONS. Norovirus and Sapovirus. Hepatitis A Virus. Hepatitis E Virus, an Etiological Agent of Foodborne and Waterborne Hepatitis. Astroviruses. Rotavirus. Emerging Foodborne Pathogenic Kobuvirus, Picobirnavirus, and Torovirus. Prions
£171.00
Headline Publishing Group Immune Resilience
Book SynopsisYour ability to fight off infections and viruses is determined by your immune system. It may be that you fall ill more frequently than those around you. But this is not something you just have to live with - your immune resilience can be improved.Clinical nutritionist Romilly Hodges offers science-based nutritional and lifestyle advice on how to build your immune resilience.Exploring how our bodies protect us from disease, Immune Resilience will allow you to identify ways you can build your body''s defences. A personalised programme covering diet, lifestyle and stress will help you achieve this. Did you know that sleep is connected to immune memory? And that good germs increase your immunity? You can even undertake exercises that boost immunity.With healthy recipes, a supplements guide and information on specific infections, Immune Resilience allows you to take control of your health.
£14.24
Little, Brown & Company Flush: The Remarkable Science of an Unlikely
Book SynopsisFor readers of Giulia Enders' Gut and Bill Bryson's The Body, a surprising, witty and sparkling exploration of the teeming microbiome of possibility in human feces from microbiologist and science journalist Bryn Nelson.The future is sh*t: the literal kind. For most of human history we've been, well, disinclined to take a closer look at our body's natural product-the complex antihero of this story-save for gleaning some prophecy of our own health. But if we were to take more than a passing look at our poop, we would spy a veritable cornucopia of possibilities. We would see potent medicine, sustainable power, and natural fertilizer to restore the world's depleted lands. We would spy a time capsule of evidence for understanding past lives and murderous ends. We would glimpse effective ways of measuring and improving human health from the cradle to the grave, early warnings of community outbreaks like Covid-19, and new means of identifying environmental harm-and then reversing it.Flush is both an urgent exploration of the world's single most squandered natural resource, and a cri de coeur (or cri de colon?) for the vast, hidden value in our "waste." Award-winning journalist and microbiologist Bryn Nelson, PhD, leads readers through the colon and beyond with infectious enthusiasm, helping to usher in a necessary mental shift that could restore our balance with the rest of the planet and save us from ourselves. Unlocking poop's enormous potential will require us to overcome our shame and disgust and embrace our role as the producers and architects of a more circular economy in which lowly byproducts become our species' salvation. Locked within you is a medicine cabinet, a biogas pipeline, a glass of drinking water, a mound of fuel briquettes; it's time to open the doors (carefully!). A dose of medicine, a glass of water, a gallon of rocket fuel, an acre of soil: sometimes hope arrives in surprising packages.
£16.14
Springer International Publishing AG Bioprocess and Analytics Development for
Book SynopsisThis book reviews the knowledge, methods and available techniques in the rapidly advancing field of virus based vaccines and gene therapeutics. It also highlights new innovative tools and interdisciplinary techniques for bioprocess development and analytics of viruses and viral vectors. As such, it provides a timely and highly relevant resource, since current advances in pharmaceutical research have seen the rise of vaccines and advanced therapeutics and medicinal products (ATMPs), that rely on the power of viruses. However, developing bioprocesses and analytics required to create this often called “magic bullet” (i.e. gene therapy) remains an extremely challenging and costly task. This book offers strategies for overcoming hurdles and difficulties within in all the necessary steps of viral vector development - from scalability to purification methods and quality control. The book is intended for researchers working in academia or industry, as well as graduate students pursuing a career in virology.Table of ContentsSee attachments
£999.99
Springer Antimicrobials in Livestock 2 Choices of Prevention and Treatment
Book SynopsisChoice of the Antimicrobial Drug and Dosing Schedules Optimisation Using PK/PD Characteristics.- Swine.- Poultry.- Cattle.- Antimicrobial Considerations for Horses.
£999.99
De Gruyter De Gruyter Handbook of Social Epidemiology
£131.85
Urban & Fischer/Elsevier BASICS Medizinische Mikrobiologie Hygiene und
Book Synopsis
£24.30
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Korea: A Geomedical Monograph of the REPUBLIC OF KOREA
Book SynopsisFor over 30 years I have been engaged as a parasitolo nitz, Springer-Verlag, Heidelberg, was arranged in the pres gist in research on endemic diseases in our land. However, ence of Professor Jusatz. lt was indeed a great honor for I have been somewhat dissatisfied within my heart of me, but I also felt a very heavy responsibility; how to set hearts from the point of view of a medical person. Most of up the scheme, how to collect the materials, how to di gest, analyze and compile them in accordance with the us, myself included, handle disease sectionally, not com prehensively. Clinicians pay more attention to finding ef original goals. I frankly confess to realizing how limited fective drugs, medical scientists concentrate more effort my knowledge was at the same time. Poor editing would on clarifying pathologic etiology, and public health work result in dishonor not only to myself, but to my country ers are more concerned with environmental sanitation. as well. Now at this juncture, the point of editing, I am filled Thus, most of us generally neglect to search out the with deep emotion. In spite of limited time and knowl causal relation of a certain disease. For a disease to be established various factors must be involved: agent, ecolo edge, this manuscript will be prepared for edition at all gy, hosts, carriers, transmitters, habits, geographic and events.Table of ContentsA. The Land and Its People.- B. Health Facilities, the Health Professions, and Public Health Services.- C. The Diseases of the Country.- D. Factors Affecting Health Problems.- References.- Illustrations.- Maps.- Figures.- Fig. 1. Monthly temperature in Seoul by means (1931–I960).- Fig. 2. Mean air temperature (°C) Annual.- Fig. 3. Mean air temperature (°C) January.- Fig. 4. Mean air temperature (°C) August.- Fig. 5. Amount of precipitation (mm) annual.- Fig. 6. Age distribution 1970.- Fig. 7. Age distribution 1975.- Fig. 8. Development of total population, population of 14 years and over and economically active population, employment by industry.- Fig. 9. Korean farm house type: Central Korean type (Gyeong-gi Do).- Fig. 10. Korean farm house type: Southern Korean type (Jeonra Nam Do).- Fig. 11. Anatomical chart in Ancient Korean Medicine.- Fig. 12. Prevalence of radiological active pulmonary tuberculosis by age (1965, 1970, 1975).- Fig. 13. Incidence curve of Korean hemorrhagic fever (1951–1971).- Fig. 14. Number of gonococcus positive specimens examined during the years 1969–1973 at Severance Hospital Laboratory.- Fig. 15. Quantitative levels of nutrition in Korea.- Fig. 16. Qualitative levels of nutrition in Korea.- Fig. 17. Korean recommended dietary allowances, energy (Cal/day/adult).- Fig. 18. Korean recommended dietary allowances, protein (g/day/adult).- Maps.- Map-Plate.- Map 1 Orography of Korea 1: 3 000 000 Map-Plate.- Map 2 Administration Republic of Korea 1: 1 500 000 Map-Plate.- Map 3 Distribution of Population, Republic of Korea.- Map 3 a Net Migration in and out of Seoul.- Map 3 b Net Migration in and out of Busan.- Map 3 c Invasion Routes of Cholera.- Map-Plate.- Map 4 Health Facilities, Republic of Korea.- Map 4 a Distribution of Leprosy Patients by Birth Place.- Map 4 b Morbidity Rate of Japanese Encephalitis Map 4 c Distribution of Microfilaria Positive Cases Map-Plate.- Map 5 Agrargeographical Survey.- Map 5a Example of Land Use: Alluvial Plain (Honom Plain Near Iri, Province Jeonra Bug Do).- Map 5 b Example of Land Use: Hilly Area (Near Jochiweon, Province Chungcheon Nam Do).- Map 5 c Example of Land Use: Mountainous Area (Taebaeg Mountains West of Mugho, Province Gang-weon Do).
£42.74
Grin Verlag Gmbh Biological effects of radiofrequency Influence of sub lethal microwave radiation on bacterial growth enzyme activity and exopolysaccharide production
£35.92
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Viren!: Helfer, Feinde, Lebenskünstler - in 101
Book SynopsisEinblicke in einer verborgene WeltViren sind Grenzgänger des Lebens. Mikroskopisch klein, als Krankheitserreger gefürchtet, doch in ihrer Vielfalt und in ihrer Bedeutung für die biologischen Netzwerke auf der Erde und für die Evolution des Lebens erst ansatzweise verstanden - und immer wieder für Überraschungen gut. Viren sind Opportunisten, die oft geduldig auf ihre Chance warten - in Ruhestadien oder eingebettet in das Erbgut ihrer Wirte -, und Meister der Anpassung. Ihre Vermehrungsstrategien und Übertragungsmechanismen sind so vielfältig wie ihre Erscheinungsformen. Die meisten Viren sind "nur" Nucleinsäuren in einer Proteinhülle, aber sie kapern Pflanzen-, Tier- und Bakterienzellen, nisten sich dort langfristig ein oder übernehmen unmittelbar die genetische Kontrolle. Dieser Band eröffnet einen faszinierenden Blick auf das ganze Panorama dieser Lebenskünstler, die wir gewöhnlich als Feinde betrachten, die aber auch Helfer sein können. Nach einer Einführung in die Grundlagen der Virologie - was genau sind Viren, woraus bestehen sie, wie sehen ihre Lebenszyklen aus, welche Evolutionspfade haben sie beschritten? - liefern 101 Porträts detaillierte Einblicke in die besonderen Eigenschaften und Fähigkeiten einzelner Virustypen, vom Grippeerreger bis zum Bakteriophagen T4, vom Tabakmosaikvirus bis zu den gefürchteten Ebola-, Zika- und Dengue-Viren.Trade Review“... Basisinformationen zum jeweiligen Virus vermittelt eine kurze, aber prägnante und äußerst verständliche Beschreibung. Übersichtliche und einprägsame Zeichnungen erleichtern das Verständnis bestimmter Besonderheiten. Zahlreiche Aufnahmen von Viren lassen sie bei allem Schrecken, den sie verursachen können, in ganz neuem Bild erscheinen.” (Dr. Thomas Patzelt, Hehlen, in: Rundschau für Fleischhygiene und Lebensmittelüberwachung RLF, Jg. 73, Februar 2021)Table of ContentsViren des Menschen.- Viren der Wirbeltiere.- Viren der Pflanzen.- Viren der Wirbellosen.- Viren der Pilze und Protisten.- Viren der Bakterien und Archaeen.
£29.99
WW Norton & Co Did You Just Eat That Two Scientists Explore
Book SynopsisA rollicking yet rigorous inquiry that follows the science of germs into the kitchen, restaurant and everywhere else you eat and drink.
£18.04
John Wiley and Sons Ltd Essential Microbiology for Pharmacy and
Book SynopsisThis text is an essential study guide for undergraduates studying microbiology modules on degree courses in pharmacy and the pharmaceutical sciences.Trade Review“As a quick review for budding pharmaceutical chemists who are learning pharmaceutical microbiology, this book could be useful. It is generally well written and presents a brief outline of the topics that it seeks to cover.” (Doody’s, 21 June 2013) Table of ContentsPreface vii Part I Characteristics of microorganisms Chapter 1 The microbial world 3 Chapter 2 Handling and growing microorganisms 11 Chapter 3 Bacterial structure and function 21 Chapter 4 Mycology: the study of fungi 33 Chapter 5 Protozoa 43 Chapter 6 Viruses and viral infections 49 Chapter 7 Characteristics of other microorganisms and infectious agents 57 Part II Microorganisms and the Treatment of Infections Chapter 8 Infection and immunity 65 Chapter 9 The selection and use of antibiotics 79 Chapter 10 Antibacterial antibiotics 87 Chapter 11 Antifungal agents 95 Chapter 12 Antiviral agents 103 Chapter 13 Antibiotic resistance 117 Chapter 14 Antibiotic stewardship 127 Part III Microorganisms and the Manufacture of Medicines Chapter 15 Bioburdens: counting, detecting and identifying microorganisms 137 Chapter 16 Antiseptics, disinfectants and preservatives 149 Chapter 17 The manufacture of medicines: product contamination and preservation 161 Chapter 18 The design of sterilization processes 175 Chapter 19 Sterilization methods 183 Chapter 20 The use of microorganisms in the manufacture of medicines 197 Index 209
£33.20
John Wiley & Sons Inc Infections in Pregnancy
Book SynopsisAn infection that occurs during pregnancy presents a constellation of problems above and beyond those normally associated with the disease. Even a relatively minor infection can threaten the lives of both mother and fetus and cause serious birth defects; and many conventional treatments can produce disastrous side effects during pregnancy. Over the past half-decade, enormous strides have been made in our ability to understand, diagnose, and treat infections in pregnant women. Infections in Pregnancy, Second Edition, is expanded to cover the latest and most useful guidelines for understanding, diagnosing, and treating infections during pregnancy. This comprehensive volume contains in-depth explanations of dozens of diseases and their pathologies, from common infections, such as human papilloma virus, to new and rare diseases. It provides important information on the administration, monitoring, and side effects of new antibiotics; reviews the Centers for Disease Control and PrevTrade Review"This book brings together all of these infections and as such is a comprehensive review of the subject." --Journal of Obstetrics and Gynecology, Volume 19, Number 3, 1999Table of ContentsPartial table of contents: Microflora of the Genital Tract. Antibiotic Usage in Pregnancy. Acute Chorioamnionitis. Postpartum Endometritis. Episiotomy Infection and Dehiscence. Soft-Tissue Infection. Syphilis in Pregnancy. Sexually Transmitted Diseases: I Gonorrhea and Chlamydia. Sexually Transmitted Diseases: II Chancroid, Lymphogranuloma Venereum, Granuloma Inguinale, Molluscum Contagiosum, Pediculosis Pubis, and Scabies. Hepatitis in Pregnancy. Varicella-Zoster Infection in Pregnancy. Human Immunodeficiency Virus Infection in Pregnancy. Mumps in Pregnancy. Measles in Pregnancy. Influenza Infection in Pregnancy. Protozoan Infection in Pregnancy. Pneumonia in Pregnancy. Preconceptual Counseling. Index.
£217.76
John Wiley & Sons Inc Gastroenteritis Viruses No 238 Novartis
Book SynopsisThis important book covers the structure and molecular biology of small round structured viruses (SSRVs) such as caliciviruses and astroviruses, and the basic pathology of infection. It provides readers with the knowledge needed to make progress in the prevention and treatment of these infections.Table of ContentsIntroduction (M. Estes). Gastroenteritis Viruses: An Overview (R. Glass, et al.). Structural Studies on Gastroenteritis Viruses (B. Prasad, et al.). Early Events of Rotavirus Infection: The Search for the Receptor(s) (C. Arias, et al.). Rotavirus RNA Replication and Gene Expression (J. Patton). Pathogenesis of Rotavirus Gastroenteritis (M. Estes, et al.). Correlates of Protection Against Rotavirus Infection and Disease (P. Offit). Rotavirus Epidemiology and Surveillance (U. Desselberger, et al.). A Rotavirus Vaccine for Prevention of Severe Diarrhoea of Infants and Young Children: Development, Utilization and Withdrawal (A. Kapikian). The Molecular Biology of Human Caliciviruses (I. Clarke & P. Lambden). Molecular Epidemiology of Human Enteric Caliciviruses in The Netherlands (M. Koopmans, et al.). Molecular Biology of Astroviruses: Selected Highlights (S. Matsui, et al.). Molecular Epidemiology of Human Astroviruses (S. Monroe, et al.). Enteric Infections with Coronaviruses and Toroviruses (K. Holmes). Viruses Causing Diarrhoea in AIDS (R. Pollok). Treatment of Gestrointestinal Viruses (M. Farthing). Summing-Up (M. Estes). Index of Contributors. Subject Index.
£89.06
John Wiley & Sons Inc A Practical Guide to Clinical Bacteriology
Book SynopsisInterspersed with cartoons which are simultaneously educational and amusing, this reference examines the principles of bacteriology. It has been designed as a handbook to give medical students ready access to all types of bacteria and their treatment.Table of ContentsPartial table of contents: Classification of Bacteria. Ecology and Spread of Bacteria. Pathogenesis of Bacterial Infections. Laboratory Diagnosis of Bacterial Infections. Antimicrobial Agents. Sterilisation and Disinfection. Immunisation Against Bacterial Infections. Clinical Syndromes. The Stapylococci. Bacillus Species. Listeria. The Clostridia. Treponema Species. Borrelia Species. Legionella. Brucella Species. Franciscella, Yersinia and Pasteurella Species. Coliforms, Pseudomonads and Allied Organisms. Salmonella Species. Shigella Species. Vibrios. Helicobacter Pylori. Bacteroides Species. The Mycobacteria. The Mycoplasmas. The Chlamydiae. The Rickettsiae. Index.
£95.36
John Wiley & Sons Inc Communicable Disease
Book SynopsisCommunicable Disease Epidemiology and Control Edited by Norman Noah King''s College School of Medicine and Dentistry, London, UK, and Mary O''Mahony Public Health Laboratory Service, London, UK With the growing interest in communicable diseases and their control worldwide, largely due to new and re-emerging infections, there is a need for up-to-date information in this continually changing field. Timely and wide ranging, Communicable Disease: Epidemiology and Control addresses many of the contemporary issues and provides: * Detailed and concise examination of management issues, such as commissioning and contracting, setting up an incident room, and legal aspects * A practical approach * An examination of a wide spectrum of issues in communicable diseases, including cholera, tuberculosis, Helicobacter pylori, and sexually transmitted diseases This volume is an invaluable resource for microbiologists, epidemiologists and all professionals involved in public health.Table of ContentsEPIDEMIOLOGY. Global Trends in Communicable Disease Control (A. Cliff & P. Haggett). Recent Trends in the Epidemiology and Management of Sexually Transmitted Infections (I. Simms & A. Nicoll). The Global Resurgence of Cholera (E. Mintz, et al.). The Resurgence of Tuberculosis (J. Grange). The Epidemiology of Hantavirus Pulmonary Syndrome (R. Khabbaz & J. Childs). Consequences of Helicobacter pylori Infection (R. Feldman & D. Strachan). MANAGEMENT ISSUES. Commissioning and Contracting Issues in Communicable Disease Control (G. Duckworth & A. Cummins). Setting Up an Incident Room (E. Mitchell). Legal Aspects of Communicable Disease Control (M. Painter & J. Button). Surveillance of Infectious Disease in a Region (S. Palmer). Appendix. Index.
£227.66
John Wiley & Sons Inc The Eradication of Infectious Diseases
Book SynopsisIn 1993, an International Task Force for Disease Eradication evaluated over 80 potential candidate diseases and made recommendations. However, little has been done to develop the science of eradication systematically. This book reports the findings of a multidisciplinary workshop on the eradication of infectious diseases. It reviews the history of eradication efforts and lessons from previous campaigns and distinguishes among eradication, elimination, and control programs and extinction of an etiologic agent. It addresses a wide range of related issues, including biological and socio-political criteria for eradication, costs and benefits of eradication campaigns, opportunities for strengthening primary health care in the course of eradication efforts, and other aspects of planning and implementing eradication programs. Finally, it stresses the importance of global mechanisms for formulating and implementing such programs.Table of ContentsWhat Is Eradication? (F. Fenner, et al.). Lessons from Previous Eradication Programs (A. Hinman D. Hopkins). The Role of Mathematical Models in Eradication of Infectious Disease (G. Medley, et al.). Group Report: How Is Eradication to Be Defined and What Are the Biological Criteria? (E. Ottesen, et al.). Disease Eradication Initiatives and General Health Services: Ensuring Common Principles Lead to Mutual Benefits (R. Aylward, et al.). Economic Appraisal of Eradication Programs: The Question of Infinite Benefits ( A. Acharya C. Murray). An Economic Perspective on Programs Proposed for Eradication of Infectious Diseases (M. Gyldmark A. Alban). Group Report: What Are the Criteria for Estimating the Costs and Benefits of Disease Eradication? (R. Hall, et al.). Roles for Public and Private Sectors in Eradication Programs (C. de Quadros, et al.). Overcoming Political and Cultural Barriers to Disease Eradication (S. Foster). Advantages and Disadvantages of Concurrent Eradication Programs (S. Cochi, et al.). Designing Eradication Programs to Strengthen Primary Health Care (C. Taylor R. Waldman). Group Report: What Are the Societal and Political Criteria for Eradication? (S. Cochi, et al.). Are There Better Global Mechanisms for Formulating, Implementing, and Evaluating Eradication Programs? (I. Arita). Thoughts on Organization for Disease Eradication (W. Foege). Group Report: When and How Should Eradication Programs Be Implemented? (R. Goodman, et al.). Indexes.
£276.26
John Wiley & Sons Inc Cellular Microbiology BacteriaHost Interactions
Book SynopsisThis text is for advanced undergraduates of microbiology and medical microbiology, presenting a comprehensive introduction to late-1990s molecular biology of the interactions between bacteria and eukaryotic cells, and their relevance to human diseases.Trade Review"A splendidly written book...""...the authors have achieved their goal and the book should be useful to students and researchers in many subject areas." --Microbiology Today, November 2000Table of ContentsBACKGROUND TO CELLULAR MICROBIOLOGY. An Introduction to Cellular Microbiology. The Cellular Biology Underlying Prokaryotic-Eukaryotic Interactions. Prokaryotic and Eukaryotic Signalling Mechanisms. Molecular Techniques Defining Bacterial Virulence Mechanisms. PROKARYOTIC-EUKARYOTIC INTERACTIONS IN INFECTION. Bacterial Adhesion to Host Cells. Bacterial Invasion of Host Cells. Bacterial Protein Toxins: Agents of Disease and Probes of Eukaryotic Cell Behaviour. The Innate Immune Response and Bacterial Infections. Acquired Immunity in the Defence Against Bacteria. Future Developments in Cellular Microbiology. Index.
£125.06
Harvard University Press Suppressing the Diseases of Animals and Man
Book SynopsisTheobald Smith (18591934) is widely considered to be America's first significant medical scientist and the world's leading comparative pathologist. This is the first book-length biography of Smith to appear in print, and is based primarily on personal papers and correspondence that have remained in the possession of his family until now.Trade ReviewThis dedication to microbiologist Smith provides a detailed account of a lifelong passion for using science to alleviate human suffering. Dolman and Wolfe meticulously investigate factors in Smith’s upbringing that led him to studying medicine… The authors recount Smith’s associations with notable scientists who led him to pursue medical studies emphasizing pathology. The list of colleagues who influenced Smith’s research reads like a who’s who of microbiology. Smith’s collaborations include other famous microbiologists who investigated infectious bacterial diseases of animal and humans. Each chapter presents Smith’s research according to the chronology of his life and concurrent developments in medicine and microbiology, and discusses his contributions to controlling tragic livestock diseases such as cattle fever, hog cholera, and swine plague. -- B. R. Shmaefsky * Choice *
£35.96
