Maturation and ageing Books

Book SynopsisIn this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine's 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help readers live younger, longer.For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That''s because ageing is not a disease it is inevitable.But what if everything you think you know about ageing is wrong?What if ageing is a disease? And that disease is curable.In LIFESPAN, Dr. David Sinclair, one of the world's foremost authorities on genetics and ageing, argues just that. He has dedicated his life's work to chasing more than a longer lifespan he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory ofTrade Review‘If you ever wondered how we age, if we can slow or even reverse aging, and if we can live a healthy 100 plus years, then David Sinclair’s new book Lifespan, which reads like a detective novel, will guide you through the science and the practical strategies to make your health span equal your lifespan, and make your lifespan long and vibrant.’– Mark Hyman, MD Director, Cleveland Clinic Center for Functional Medicine and #1 New York Times bestselling author ‘This is the most visionary book about aging I have ever read. Seize the day–and seize this book!’– Dean Ornish, MD, founder & president, Preventive Medicine Research Institute, and New York Times bestselling author of UnDo It! "In this insightful and provocative book that asks questions about how we age, and whether humans can overcome decay and degeneration, Sinclair grapples with some of the most fundamental questions around the science of aging. The result is an elegant and exciting book that deserves to be read broadly and deeply." Author: Siddhartha Mukherjee, Pulitzer Prize–winning and #1 New York Times bestselling author “There are few books that have ever made me think about science in a fundamentally new way. David Sinclair’s book did that for me on aging. This is a book that anyone who ages must read.” Author: Leroy Hood, PhD, professor at the California Institute of Technology, inventor, entrepreneur, member of all three US National Academies, and co-author of Code of Codes

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Book Synopsis''I am blown away by the level of detail Phil Cavell brings to his work.'' Elinor Barker MBE, multiple world champion and Olympic gold medallist''The Midlife Cyclist is a triumph'' Cycling Plus''An amazing accomplishment... a simple-to-understand précis of your midlife as a cyclist you won''t want to put it down.'' Phil Liggett, TV cycling commentator''Phil is eminently qualified to write The Midlife Cyclist. Well, he is certainly old enough.'' Fabian Cancellara, Tour de France rider and two-time Olympic championRenowned cycling biomechanics pioneer, Phil Cavell, explores the growing trend of middle-aged and older cyclists seeking to achieve high-level performance. Using contributions from leading coaches, ex-professionals and pro-team doctors, he produces the ultimate manifesto for mature riders who want to stay healthy, avoid injury and maximise their achievement levels.Time''s arrow traditionally plots an incremental pathTrade ReviewA must-read... this brilliant book shows you that getting older doesn't mean getting slower! -- Alan Murchison, The Cycling chef and masters cycling championPhil is eminently qualified to write The Midlife Cyclist. Well, he is certainly old enough. -- Fabian Cancellara, Tour de France rider and two-time Olympic championA road-map for the mature cyclist * Cycling News *Phil's book can help you be as good today as you always said you were -- Carlton Kirby, Eurosport commentatorI am blown away by the level of detail Phil Cavell brings to his work -- Elinor Barker MBE, multiple world champion and Olympic gold medallistAn amazing accomplishment... a simple-to-understand précis of your midlife as a cyclist – you won't want to put it down. -- Phil Liggett, TV cycling commentatorI’m determined to grow old gracefully in lycra, and Phil Cavell has been helping me to do it successfully for years. -- Gary KempThe Midlife Cyclist is entertaining, insightful, well-researched and vital reading for all youngsters over forty who have a love affair with the bike. -- Norman FosterA must for the older athlete, it's motivated me to train harder again. -- Sir Rocco ForteThe Midlife Cyclist is a triumph * Cycling Plus *Are you middle-aged? Are you slower than you used to be, more tired? Read this book. It will help you. * The Cycling Independent *Table of ContentsPrologue Introduction 1 The Ageing Cyclist – Growing Old Disgracefully 2 It Is About the Bike 3 Will I Die? 4 Midlife Performance – Too Late For Speed? 5 Bikes, Bike Fit and Biomechanics 6 Bike, What Bike? 7 Food for Sport 8 The Mindful Cyclist Epilogue Midlife Cyclists: Case Studies

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Book Synopsis***'Are you aging fabulously? Here's how.' Anna Murphy, The Times'A lovely book celebrating female beauty over 40.' Top Sante'You become what you see. What you see determines what you believe - and the most powerful way of inspiring people is with images. My goal with AndBloom is to motivate women to embrace life without fear. To provide examples of women between the age of 40 and, currently, 100, so that any woman can open this book and see themselves recognized.' Denise Boomkens launched the AndBloom project on Instagram in 2018, to create a 'happy place for women over 40' - a community where women can be themselves and where aging is celebrated instead of feared. In this, her first book, she shares her own experiences of aging and brings together portraits and interviews with more than 100 extraordinary 'ordinary' women to create both a gloriously illustrated celebration of female beauty over 40 and an empowering handbook to aging happily.Trade ReviewThe account is dedicated to celebrating the beauty of women over 40 years old and we're absolutely in love with it. Boomkens shares self-portraits and portraits of other women over 40 in an attempt to show that all women are beautiful and that all women deserve to look and feel their best, no matter their age. * My Daily Magazine *

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Book SynopsisExamining cultures as diverse as long-house dwellers in North Borneo, African farmers, Welsh housewives, and postindustrial American workers, this title redefines the anthropological study of menstrual customs.Trade Review"The first book on the anthropology of menstruation to be published by a major university press." -- Becky Vorpagel Journal of American Folklore "A major innovation is the deliberate and consistent focus on women's views and their participation in social responses to bodily processes." -- Terence Hays Journal of the History of Sexuality "Reclaiming the female body, retrieving it piece by piece from the grip of patriarchal culture and medical practice, has been a central feminist goal for each of the last two decades. Menstruation ... is now front and center on the feminist agenda as a topic that needs to be rethought ... Blood Magic ... [is] among a larger set of books that are seeking simultaneously to dismantle the traditional formulations and to replace them with a woman-centered set of understandings ... [the book]... not only clear[s] and point[s] the way for a new woman-centered scholarship on menstruation but demonstrate[s] its significance to the feminist agenda." -- Anna Meigs Signs "The first major collection on anthropological interpretations of menstruation... The editors contribute a lengthy, useful introduction to this biological phenomenon and the interpretations given to it by different peoples; moreover, they provide discussions for each section ... A well-edited and useful contribution to the continually growing literature on the cultural constructions of gender." -- L. Beck Choice, "Outstanding Title!" "Menstrual taboos have long been a favorite subject of ethnographic inquiry, but in the past their study has suffered from both an ethnocentric and male-centered bias. Burdened by their own set of 'menstrual taboos,' ethnographers have too often assumed they knew what those of another culture meant. Blood Magic, a collection of essays by nine fieldworkers in anthropology and related disciplines, marks a welcome departure from earlier studies in a number of ways. It derives its perspective from women's studies in recognizing the need to focus on women's experiences as well as those of men, and in recognizing the importance of female fieldworkers to do this. This is the first book-length collection of essays to grow out of recent cultural anthropological research on menstruation. Never before has the study of menstruation been so well informed by a combination of fieldwork and theoretical approaches to the study of gender and the symbolism of the body. This is the first book-length collection of essays to grow out of recent cultural anthropological research on menstruation. Never before has the study of menstruation been so well informed by a combination of fieldwork and theoretical approaches to the study of gender and the symbolism of the body ... This is a well-constructed and well-researched collection, grounded in received anthropological theory, yet looking far beyond it." -- Jennifer Livesay Folklore ForumTable of ContentsAcknowledgments Editors' Note PART I INTRODUCTION 1. A Critical Appraisal of Theories of Menstrual Symbolism Thomas Buckley and Alma Gottlieb PART II MENSTRUAL IMAGES, MEANINGS, AND VALUES 2. Menstrual Cosmology among the Beng of Ivory Coast Alma Gottlieb 3. Mortal Flow: Menstruation in Turkish Village Society Carol Delaney 4. Menstruation among the Rungus of Borneo: An Unmarked Category Laura W. R. Appell PART III THE SOCIOLOGY OF MENSTRUAL MEANINGS 5. Menstrual Politics: Women and Pigs in Rural Portugal Denise L. Lawrence 6. Menstrual Symbolism in South Wales 137 Vieda Skultans 7. Premenstrual Syndrome: Discipline, Work, and Anger in Late Industrial Societies Emily Martin PART IV EXPLORATORY DIRECTIONS: MENSES, CULTURE, AND TIME 8. Menstruation and the Power of Yurok Women Thomas Buckley 9. Heavenly Bodies: Menses, Moon, and Rituals of License among the Temne of Sierra Leone Frederick Lamp 10. Menstrual Synchrony and the Australian Rainbow Snake Chris Knight Notes References Contributors Index

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Book SynopsisThere''s nothing like a good puzzle to keep your mind active! Enjoy hours of fun with this collection of simple and soothing brain games.Whether you love a word search, have a keen eye for spot-the-differences or prefer colouring in, the wide variety of games in this puzzle book means there''s something for everyone. The extra-easy activities in these pages will help keep your brain sharp and improve your mental acuity.You might like to try completing these puzzles on your own. Alternatively, you might find it useful to have a helping hand from someone like a friend, carer or relative - at least to start with. Either way, Brain Games for Seniors is designed so that you can have a go and see what suits you best.In this book, you will find:- Basic word-based puzzles like crosswords and word searches- Super-simple image games including spot-the-differences and odd-one-outs- Colouring pages filled with beautiful designs- A clear and easy-to-follow answers section at the back of the bookFrom gardening to sports, the 78 puzzles in this book cover a broad range of fun topics. Whatever your interests, these engaging brain games are sure to keep your mind active and entertained!

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Book SynopsisMireille shares the secrets and strategies of aging with attitude and joy, offering personal anecdotes while divulging French women''s most guarded secrets about looking and feeling great. With her signature blend of wit, no-nonsense advice and storytelling flair she addresses everything from lotions and potions to diet, style, friendship and romance. For anyone who has ever spent the equivalent of a mortgage payment on anti-aging lotions or procedures, dressed inappropriately for their age, gained a little too much in the middle or accidentally forgotten how to flirt, here is a proactive way to stay looking and feeling great, without declaring bankruptcy or resorting to surgery.Trade ReviewLike a fabulous friend sharing her secrets, Mireille divulges, encourages and inspires. And she does it with joy. -- Pamela DruckermanFrench women have incredible style and confidence. Mireille is an inspiration and her book is a must-read for any woman wanting to look better and ultimately feel more beautiful. -- Bobbi BrownFrench Women Don’t Get Facelifts is [...] ostensibly as light as a meringue but actually as satisfying as Guilano’s recipe for duck with caramelised mango [...] It’s a “no” not only to the scalpel and Botox needle, but also to fad diets and costly anti-ageing serums [...] It’s a Oui, Oui, Oui to facials [and]diets “where nothing is restricted but everything is encouraged in moderation”. * The Times *C'est magnifique! * Today (US) *It's hard to resist a chance to tackle the wrinkles in your self-esteem with Guiliano's wholly engaging take on how women of 40 and upwards can "attack" the ageing process with "attitude and style", whether through skincare secrets and fashion tips or the role of relationships and the importance of relaxation. Mais... it's about so much more than botox. I was completely won over by it. * Caroline Sanderson, The Bookseller *

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Book Synopsis______________ 'Elegant, filthy – and quite possibly the queerest thing you will read all year.' - Guardian 'Intriguing and inventive.' - Electric Literature, "Most Anticipated LGBTQ+ Book of the Year" 'A dizzyingly enticing and kaleidoscopic take on the spectrum of sexual experiences.' - Publishers Weekly, starred review _____________ A daring, category-confounding, and ruthlessly funny novel from National Book Award honored author Edmund White that explores polyamory and bisexuality, ageing and love. Sicilian aristocrat and musician, Ruggero, and his younger American wife, Constance, agree to break their marital silence and write their Confessions. Until now they had a ban on speaking about the past, since transparency had wrecked their previous marriages. As the two alternate reading the memoirs they’ve written about their lives, Constance reveals her multiple marriages to older men, and Ruggero details the affairs he’s had with men and women across his lifetime—most importantly his passionate affair with the author Edmund White. Sweeping outward from the isolated Swiss ski chalet where the couple reads to travel through Europe and the United States, White’s new novel pushes for a broader understanding of sexual orientation and pairs humor and truth to create his most fascinating and complex characters to date. As in all of White’s earlier novels, this is a searing, scintillating take on physical beauty and its inevitable decline. But in this experimental new mode—one where the author has laid himself bare as a secondary character—White explores the themes of love and age through numerous eyes, hearts and minds. Delightful, irreverent, and experimental, A Previous Life proves once more why White is considered a master of American literature.Trade ReviewElegant, erudite, raunchy and fun, America’s great Man of Letters is working at the top of his form, giving us a pair of portraits hung against the pattern of history. What a joy to read this master of prose and invention! * Andrew Sean Greer, Pulitzer Prize winning author of LESS *The best book in Edmund White's long and extraordinary career * Benjamin Moser, Pulitzer Prize winning author of SONTAG: HER LIFE AND WORK *White's project, as always, is to show us the human: the human body as defined by its urges and needs, and the human heart as it evolves through time and experience. In A Previous Life, he also gives us daring experiments of form, of autofiction, and of storytelling. Fresh and inventive and wise * Rebecca Makkai, author of THE GREAT BELIEVERS *An erotically charged and ingenious metafictional story of a married couple … A dizzyingly enticing and kaleidoscopic take on the spectrum of sexual experiences * Publishers Weekly, starred review *Humorous and nearly always irreverent ... An erotically charged literary romp facing the loss of physical beauty and the inevitable passage of time * Booklist *

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Book SynopsisThere''s nothing like a good word search to keep your mind active! Enjoy hours of fun with this collection of simple and soothing puzzles.Word searches are a wonderful way to gently exercise your brain and keep yourself entertained. Whether you''ve got a keen eye for detail or enjoy problem solving, this collection of extra-easy activities will provide cognitive stimulation and help enhance your memory. You might like to try completing these word searches on your own. Alternatively, you might find it useful to have a helping hand from someone like a friend, carer or relative - at least to start with. Either way, Brain Games for Seniors: The Word Search Edition is designed so that you can do whatever suits you best.In this book, you will find:- A short and helpful introduction to the collection- A total of 78 word searches, each based around a specific theme- A clear and easy-to-follow answers section at the back of the bookDesigned to be achievable as well as enjoyable, these word searches are sure to keep your mind active and entertained!

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Book SynopsisFrom the author of Period Power comes the empowering guide to menopause that all women need, packed with advice on dealing with symptoms and understanding the most effective treatment options.Three-quarters of women reaching menopause experience symptoms such as mood changes, insomnia, hot flushes, and night sweats, but there is little in the way of evidence-based information out there to help them presented in a way that''s engaging and helpful. Perimenopause Power is here to change that: finally, this is a book for women experiencing perimenopause and menopause who want to understand what''s going on with their bodies and how to deal with troublesome symptoms, but also gain valuable insights into making menopause a positive and powerful experience--yes, it''s possible!Perimenopause Power is a handbook that exudes calm positivity and makes sense of complex physiological processes in an easy-to-understand manner, helping women to uTrade ReviewAn informative must-read for any woman – whatever their age * VOGUE online *Will make you gasp at how ill-informed you are about your own body * Sunday Telegraph, Stella *Excellent -- Bryony Gordon * Daily Telegraph *An empowering manual to guide women through how to make all stages of the menopause a more positive experience * Woman & Home online *This is such an empowering guide to the perimenopause, which I hope can help many women in those early stages * Prima magazine *This empowering guide helps you navigate your hormones during this life stage, which can start in your thirties * Women's Health *A real goodie, a curve ball book which I highly recommend for women hitting their 40s – brilliantly written -- Thomasina MiersAn essential handbook to understanding our bodies * Women's Running *A hormone bible… informative, clear, funny and reassuring, full of life-enhancing, reliable information. * Simple Things *Table of ContentsIntroduction Chapter 1: WTF is Happening? Chapter 2: One Last Hurrah Chapter 3: It’s Getting Hot in Here Chapter 4: Moody Bitches Chapter 5: Waist Watching Chapter 6: All Dried Out Chapter 6: Heart of Glass Chapter 7: Boobs and Bones Chapter 8: HRT – Devil or Saviour? Chapter 9: Let’s just whip it out Chapter 10: Hormone Rehab Chapter 11: Refining and Redefining Glossary Resources References Index

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Book SynopsisDiana Moran is here to help spread the word about treatments and preventative measures we can all take to tackle osteoporosis.Written in association with the National Osteoporosis Society, this practical book is a must-have for anybody affected by osteoporosis. Packed with advice, friendly tips and ideas, and an overview of current research, and what we can all be doing to help ourselves live well.As a sufferer of osteopenia herself (an early form of osteoporosis) Diana Moran is a strong advocate for exercise, early diagnosis, weight bearing exercise, vitamin D and other measures that can be taken to tackle osteoporosis.This book contains specially designed exercises to help encourage a more active lifestyle and strengthen areas of weakness, alongside the important theory, and medical side of osteoporosis. This is an easy to digest, friendly guide for the general reader.Trade ReviewA godsend in helping us all keep osteoporosis at bay. Diana herself is a living example that exercise little and often is the way to go! -- Anne DiamondBy following Diana's exercise programme we can all do something good for ourselves to keep our bones strong and the big O at bay. -- Angela RipponDiana's book is a lifesaver and a life enhancer. Warmly recommended. -- Lynn Faulds WoodDiana Moran has promoted activity for decades, not only to slow the rate of bone loss but also to tackle the many other consequences of inactivity. This book is very, very important. -- Professor Sir Muir GrayOsteoporosis is a painful condition and this brilliant book is full of advice and exercises. Diana is such a perfect example of how keeping fit and exercising can improve your life. -- Nerys HughesDiana is living, vibrant proof of the benefits of keeping active in later years. -- Aggie MacKenzieAs we all inevitably get older osteoporosis can cripple us in our best years - so thank you Diana for all your help and hard work aimed at stopping it in its tracks! -- Chris TarrantThanks to Diana Moran, the pain of osteoporosis doesn't have to be inevitable. -- Christopher BigginsCombines advice, information and guidance with a series of simple exercises suitable for all ages. -- People's FriendTable of ContentsIntroduction Royal Osteoporosis Society Top Tips PART ONE 1. What is Osteoporosis? 2. Know Your Bones 3. Who is at Risk of Osteoporosis? 4. Bone Screening and Who is Eligible 5. Menopause and its Consequences 6. Drug Treatments for Osteoporosis 7. Diet, Supplements and Natural Alternatives PART TWO 8. Why Do We Need to Exercise? 9. Exercise Plan Warm-Up 10. Upper Body Workout 11. Lower Body Exercise 12. Osteo Relief Exercises 13. Preventing Falls

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Book SynopsisParisian blogger Mylène Desclaux assures us that we are still 'young women' in our fifties - but with more opportunities. She examines everything with humour and sensitivity - love, style, parents, children, work, nightclubs...Trade ReviewMylène's light-hearted advice is all about navigating the world with confidence * Daily Mail *

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Book SynopsisGetting older doesn't matter. Keeping active does. Sod turning sixty, make those small changes now and reap the rewards in your later decades! In the bestselling Sod Seventy! Sir Muir Gray demanded a ''bonfire of the slippers'' and a reframing of what it is to be seventy and older, and how to make the most of your seventies, by closing the ''fitness gap'' to stay fit and strong. Sod Sixty! is a fun, friendly, hands on guide to navigating your sixties - a very different decade with very different demands. Find out how to get fitter whatever your history', how to eat healthily, how to juggle looking after yourself with the responsibilities of family, friends and work, and how to make the most of this decade of change. But this is no boot camp regime. Sod Sixty! acknowledges the reality of our daily lives, and has a balanced approach, packed with achievable, practical and realistic strategies to improve your health and wellbeing. Our sixties are often thougTrade ReviewSensible and light-hearted advice * The Bookseller *Very informative guide that takes a fun, rather than a preachy tone, about making good health decisions, as well as using simple steps to cope with lots of issues that crop up as we get older. * Irish Examiner *Sixty-something GP Dr Claire Parker and public-health expert Sir Muir Gray have combined their wisdom... From eating well to keeping fit, they give inspiring advice on making the best of yourself later in life * Saga *Table of ContentsPreface 1 Getting Older Doesn't Matter: Getting Active and Getting Attitude Does 2 Keeping Active Is Fitness Friendly 3 Your Attitude and its Soulmates: Mind and Mood 4 Keeping Active is Fitness Friendly 5 Take Care of Your...Bits 6 Rhythm and Blues 7 Stuff Happens 8 Decisions, Decisions 9 Heath Care: Choosing and Using it Wisely Acknowledgements Index

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Book SynopsisMaintaining physical and mental performance with a revolutionary diet that helps prevent age-related diseases.

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Book Synopsis60 wonderful whisky and bourbon cocktails

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Book SynopsisThe Second Half of Your Life is an inspiring, motivating read that gives women a framework to create a game plan to help overcome many of the obstacles faced in the second half of life.Watch Jill’s video below to discover how to make the second half of your life the bestTrade ReviewFunny, engaging and accessible. A girlfriend’s guide to menopause and ageing. * Dr Miriam Stoppard *

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Book SynopsisThis book gives an overview of the potential and the practical details that need to be resolved to make human germline engineering possible. Chapters present the ethical and social concerns and implications of the fast-approaching capability to alter the human germline and take an active role in the future evolution of the species.Trade ReviewThe book should be commended for bringing to the fore the possibilityof germline manipulation within the next decade * New Genetics & Society *...interesting reading. * Heredity *The participants, mostly drawn from Us academic institutions, fall into three categories: eminent practising scientists; panelists, including James Watson, the co-discoverer of the structure of DNA; and commentators- scientists, ethcicists and theologians * Nature *Table of ContentsSection One ; 1. A vision for human germline engineering ; 2. The human genome project - launch pad for human genetic engineering ; 3. Ethics and Safety ; 4. Human germline gene therapy: how and why ; 5. A new front in the battel against disease ; 6. Aging as a target for genetic engineering ; 7. Reprogenetics: how reproductive and genetic technolgies will be combined to provide new opportunities for people to reach their reproductive goals ; Section Two ; Panel: The road ahead ; Section Three"R ; 1. Other voices - Introduction ; 2. Parental choices ; 3. Thoughts on the... ; 4. The psycho-social limits on human germline modification ; 5. Do we know ourselves well enough to be engineering humans? ; 6. Germline manipulation ; 7. Maximize parental choice ; 8. Our societal obligations for keeping human nature untouched ; 9. The question of purpose ; 10. Gene modification technology ; 11. Justice and the germline ; 12. Human germ line intervention: What's the fuss about? ; 13. Germline culture: The genetics of hubris ; 14. Liberty, equality, and solidarity in our genetically engineered future ; 15. Would humanity be better off...Or, what would it be better for? ; 16. Human dignity should not keep us from genetically engineering our children ; 17. Universal bioethics for the human germline ; 18. Multi-jurisdiction regulation of germline intervention 'A policy with neither virtue nor prospect of success ; Section 4. Chapter Contributors and Essay Contributors

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Book SynopsisKatie Taylor is a leading voice in the nationwide conversation around midlife and menopause. Motivated by her own debilitating experience of perimenopause and years of misdiagnosis, Katie founded her multi-award-winning platform The Latte Lounge, to provide support for all women's perimenopause, menopause, health and wellbeing needs. As well as appearing regularly on national media, Katie runs workshops to help increase awareness of menopause in the workplace and to ensure midlife women get the support they need.

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Book SynopsisKatie Piper OBE is a best-selling international author, inspirational speaker, TV presenter and charity campaigner. She is a regular panellist on ITV's Loose Women and a presenter for BBC Radio 2. Katie shared her story in a remarkable film for the Cutting-Edge strand on Channel 4 called Katie: My Beautiful Face' which was watched by over 3.5million viewers and nominated for Best Single Documentary at the BAFTA Television Awards in 2010.

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Book SynopsisSurprising guideposts to a happier life from the landmark Harvard Study of Adult DevelopmentTrade ReviewA smart, important book about human development....everything about it is profoundly, provocatively new. * SAN FRANCISCO Chronicle *

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Book Synopsis''A guide to counteract medical misogyny'' New Scientist''The world''s most famous - and outspoken - gynaecologist'' GuardianIn The Menopause Manifesto internationally renowned, New York Times bestselling author Dr Jen Gunter brings you empowerment through knowledge by countering stubborn myths and misunderstandings about menopause with hard facts, real science, fascinating historical perspective and expert advice.The only thing predictable about menopause is its unpredictability. Factor in widespread misinformation, a lack of research, and the culture of shame around women''s bodies, and it''s no wonder women are unsure what to expect during the menopause transition and beyond.Menopause is not a disease - it''s a planned change, like puberty. And just like puberty, we should be educated on what''s to come years in advance, rather than the current practice of leTrade ReviewA banger of a book that tells you everything you could possibly need to know about the menopause experience - and plenty of stuff you don't but will be glad you do. -- Sam Baker, author of The ShiftDr Jen Gunter isn't taking any prisoners (Gwyneth Paltrow included) on her mission to bust myths about midlife and medicine * The Telegraph *A guide to counteract medical misogyny ... Gunter promises to give women strength, value, agency and knowledge to help them through this transition in their life. She has unquestionably achieved that. * New Scientist *

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Book SynopsisAs the lifespan of humans increases, research into aging and its related pathological conditions is gaining momentum. This book is the first to explain protein oxidation and the aging process, focusing on the connection between protein disturbances and the oxidative stress that cells continually undergo.Trade Review“With its discussion of current concepts linked to protein oxidation and its impact on aging and the pathology of certain age-related diseases, this book is an important contribution to the field. Students, researchers, scientists, and even clinicians will benefit from it.” (Doody’s, 10 January 2013) “The format and compartmentalised writing style make this an excellent compendium of knowledge for any researcher interested in assessing our state of knowledge of protein oxidation and ageing. It is easy to find out about the current state of knowledge about a specific reaction, product, method, and/or disease and follow this up by accessing the extensive list of references.” (Chemistry & Industry, 1 July 2013)Table of ContentsIntroduction to the Wiley Series on Protein and Peptide Science xi Preface xiii 1 Oxidative Stress and Protein Oxidation 1 1.1 The Large Variety of Protein Oxidation Products, 7 1.1.1 Primary Protein Oxidation Products, 7 1.1.1.1 Carbon-Centered Radicals, 9 1.1.1.2 Thiyl Radicals, 13 1.1.1.3 Aromatic Ring-Derived Radicals, 13 1.1.1.4 Transfer between Sites, 16 1.1.2 Reactive Compounds Mediating in Protein Oxidation, 18 1.1.2.1 Hydroxyl Radical, 20 1.1.2.2 Superoxide Radicals, 21 1.1.2.3 Hydrogen Peroxide, 24 1.1.2.4 Lipid Peroxyl Radicals, 24 1.1.2.5 Alkoxyl Radicals, 24 1.1.2.6 •NO and Peroxynitrite, 25 1.1.2.7 Hypochlorous Acid, 30 1.1.3 Enzymatic Systems Playing a Role in Protein Oxidation, 31 1.1.3.1 NADPH Oxidase, 32 1.1.3.2 Lipoxygenases, 35 1.1.3.3 Protein Kinases, 35 1.1.3.4 Mixed-Function Oxidases, 36 1.1.3.5 Nitric Oxide Synthetase (NOS), 38 1.1.3.6 Myeloperoxidase, 41 1.1.3.7 Cyclooxygenase, 42 1.1.4 Protein Oxidation in Cells and Cellular Structures, 43 1.1.4.1 Protein Oxidation in Blood and Blood Cells, 43 1.1.4.2 Protein Oxidation of Glycolytic Enzymes and Mitochondria, 46 1.1.4.2.1 Glycolytic Enzymes, 48 1.1.4.2.2 Aconitase, 49 1.1.4.2.3 Carnitine Palmitoyltransferase-1, 49 1.1.4.3 Cytochrome P450 Enzymes, 49 1.1.4.4 Protein Oxidation in the Nucleus and Chromatin, 50 1.1.4.4.1 Histone Modifi cation, 50 1.1.4.5 Protein Oxidation in the Endoplasmic Reticulum, 52 1.1.4.6 Protein Oxidation in Peroxisomes, 54 1.2 Reversible Oxidative Modifi cations, 55 1.2.1 Methionine Sulfoxides and Methionine Modifi cations, 55 1.2.2 Cysteine Modifi cations and Disulfi de Bond Formation, 61 1.2.3 Surface Hydrophobicity Modifi cations, 64 1.3 Irreversible Oxidation Products, 64 1.3.1 Protein Oxidation and Enzymatic Posttranslational Modifications, 65 1.3.2 Deamidation and Transamination, 66 1.3.3 Protein Glycation and AGEs, 67 1.3.3.1 Receptor for Advanced Glycation End Products (RAGE), 75 1.3.3.2 Nε-Carboxymethyllysine and Nε-Carboxyethyllysine, 76 1.3.3.3 Pentosidine, 76 1.3.4 Racemization, 77 1.3.5 Nitrosylation, 77 1.3.6 Tyrosyl Radicals and Nitrotyrosines, 78 1.3.6.1 Dityrosines, 79 1.3.7 Protein Carbonyls, 80 1.3.8 Aldehyde–Protein Reactions, 81 1.3.8.1 MDA-Protein Adducts, 82 1.3.8.2 4-Hydroxy-2,3-Nonenal-Protein Adducts, 82 1.3.9 Cross-Linking of Proteins, 82 1.4 The Oxidation of Extracellular Matrix, Membrane and Cytoskeletal Proteins, 83 1.4.1 Collagen, 84 1.4.2 Elastin, 95 1.4.3 The Oxidation of Membrane Proteins, 97 1.4.4 Band 3, 97 1.4.5 Actin, 99 1.5 Mechanism and Factors Influencing the Formation of Protein Oxidation Products, 100 1.5.1 Redox Status, 101 1.5.2 Protein Turnover, 106 1.5.3 Metal-Catalyzed Oxidation (MCO), 107 1.5.4 Heat Shock Proteins, 109 1.6 Protein Aggregates: Formation and Specific Metabolic Effects, 111 1.6.1 Accumulation of Oxidized Proteins, 113 1.6.2 Lipofuscin and Ceroid, 115 1.7 Methods to Measure Protein Oxidation Products in Research Laboratories, 119 1.7.1 Determination of Methionine Sulfoxide Reduction and Methionine Oxidation, 120 1.7.2 Determination of Protein Glycation and Adducts, 121 1.7.3 Analysis of Isoaspartate Formation, 122 1.7.4 Measurement of Fragmentation, 122 1.7.5 Measurement of Tyrosine Oxidation, 123 1.7.6 Protein Carbonyl Measurement, 124 1.7.7 Radioactive Labeling Protocols for Proteolysis and Aggregation Measurements, 128 1.7.8 Standard Chromatographic Methods for the Measurement of Protein Modifi cations, 132 1.7.9 Liquid Chromatography Techniques Supported by Mass Spectrometry, 133 1.7.10 GC/MS, 134 1.7.11 Analysis of Protein-Bound 3-Nitrotyrosine by a Competitive ELISA Method, 134 1.7.12 Protein Oxidation Products as Biomarkers in Clinical Science, 135 References, 139 2 Removal of Oxidized Proteins 215 2.1 The Limited Repair of Some Oxidized Proteins, 216 2.1.1 Thiol Repair, 216 2.1.2 Methionine Sulfoxide Reductases, 219 2.2 Proteolysis, 221 2.2.1 The Proteasomal System and Its Role in the Degradation of Oxidized Proteins, 222 2.2.1.1 The Ubiquitin–Proteasome System (UPS), 222 2.2.1.2 The Components of the UPS, 222 2.2.1.2.1 The 20S Proteasome, 222 2.2.1.2.2 The Inducible Forms of the Proteasome and Their Function, 227 2.2.1.2.3 The 11S Regulator, 231 2.2.1.2.4 The 19S Regulator and the UPS, 233 2.2.1.2.5 The PA200 Regulator Protein, 238 2.2.1.2.6 Cellular Proteasome Inhibitors, 239 2.2.1.3 Low-Molecular-Weight Proteasome Inhibitors, 239 2.2.1.4 Cellular Function of the UPS, 241 2.2.1.5 The Degradation of Oxidized Proteins: A Function of the 20S Proteasome, 243 2.2.1.5.1 Early Studies on the Turnover of Oxidized Proteins, 244 2.2.1.5.2 In Vitro Studies and the Recognition of Oxidized Proteins by the Proteasome, 244 2.2.1.5.3 Cellular and In Vivo Studies of the Degradation of Oxidized Proteins, 248 2.2.1.5.4 The Inhibition of the Proteasome by Cross-Linked Oxidized Proteins and Proteasomal Regulation during Oxidative Stress, 251 2.3 The Role of Other Proteases in the Fate of Oxidized Proteins, 254 2.3.1 Lysosomal Degradation of Oxidized Proteins and the Role of Autophagy, 254 2.3.2 Mitochondrial Degradation of Oxidized Proteins and the Lon Protease, 256 2.3.3 The Uptake of Extracellular Oxidized Proteins and the Role of the Proteasome in Their Degradation, 258 2.3.4 Calpains and the Degradation of Oxidized Proteins, 259 2.4 Role of Heat Shock Proteins in Protein Degradation, 260 2.5 Conclusion, 262 References, 262 3 Protein Oxidation and Aging: Different Model Systems and Affecting Factors 295 3.1 Protein Oxidation during Aging: Lower Organisms and Cellular Model Systems, 297 3.1.1 Yeast, 297 3.1.1.1 Saccharomyces cerevisiae, 297 3.1.1.2 Schizosaccharomyces pombe, 301 3.1.2 Podospora anserina, 301 3.1.3 Bacteria, 302 3.1.3.1 Escherichia coli, 302 3.1.4 Cell Cultures, 304 3.2 Nonmammalian Model Systems and the Accumulation of Oxidized Proteins during Aging, 308 3.2.1 Caenorhabditis elegans, 308 3.2.2 Drosophila melanogaster, 310 3.2.3 Aquatic Systems, 313 3.2.4 Plants, 315 3.2.5 Amphibians, 317 3.3 Age-Related Protein Oxidation in Humans and Mammals, 317 3.3.1 Humans, 317 3.3.2 Animals, 319 3.3.2.1 Rabbits, 323 3.3.2.2 Mice, 324 3.3.2.3 Rats, 327 3.3.2.4 Gerbils, 329 3.3.2.5 Primates, 330 3.4 Inherited Factors Influencing Protein Oxidation during Aging, 331 3.4.1 Genetic Instability, Mutations, and Polymorphism, 331 3.4.2 Gender, 333 3.4.3 Vitagenes, 334 3.4.4 Signal Transduction and Transcription Factors, 335 3.4.5 Ion Channels, 340 3.5 Age-Related Protein Aggregate Formation in Model Systems, 341 3.6 Environmental Factors Affecting Healthy Aging, 342 3.6.1 UV-Induced Skin Photoaging and Skin Aging, 344 3.6.2 Pesticides, 348 3.6.3 Exercise, 349 3.6.4 Dietary Factors and Prevention Strategies, 351 3.6.4.1 Melatonin, 353 3.6.4.2 Growth Hormone, 354 3.6.4.3 Biotrace Metal Elements: Zinc, 356 3.6.4.4 Ascorbic Acid, 357 3.6.4.5 Vitamin E, 360 3.6.4.6 Carnitine and Acetyl-L-Carnitine, 361 3.6.4.7 Homocysteine, 362 3.6.4.8 Ubiquinone, Coenzyme Q10, 363 3.6.4.9 Carnosine, 363 3.6.4.10 Lipoic Acid, 364 3.6.4.11 N-Acetyl-L-Cysteine, 365 3.6.5 Pharmacological Response and Biotransformation in Aging, 365 3.6.5.1 Plant Extracts, 366 3.6.5.2 Polyphenols and Flavonoids, 366 3.6.5.3 Resveratrol, 367 3.6.5.4 AGE and ALE Inhibitors, 368 3.6.6 Caloric Restriction, 369 3.7 Repair and Degradation of Oxidized Proteins during Aging, 370 References, 372 4 Protein Oxidation in Some Age-Related Diseases 417 4.1 Protein Oxidation during Neurodegeneration and Neurological Diseases, 417 4.1.1 Brain Aging, 418 4.1.2 Alzheimer’s Disease, 420 4.1.3 Parkinson’s Disease, 424 4.1.4 Huntington’s Disease, 425 4.1.5 Stroke, 427 4.1.6 Amyotrophic Lateral Sclerosis, 427 4.2 Protein Oxidation in Cardiac Diseases, 429 4.2.1 Ischemia–Reperfusion, 429 4.2.2 Atherosclerosis, 430 4.3 Protein Oxidation in Diabetes, 431 4.4 Protein Oxidation in Degenerative Arthritis, 434 4.5 Protein Oxidation in Muscle Wasting and Sarcopenia, 435 4.6 Protein Oxidation in Destructive Eye Diseases, 437 4.6.1 Age-Related Macular Degeneration, 437 4.6.2 Cataract, 438 4.7 Protein Oxidation in Osteoporosis, 440 4.8 Protein Oxidation in Cancer, 441 4.8.1 Proteasome Inhibitors in Cancer Therapy, 444 4.9 Other Diseases, 446 4.9.1 Premature Aging Diseases Progeria and Werner’s Syndrome, 446 4.9.2 Renal Failure and Hemodialysis in Elderly People, 447 4.9.3 Obesity, 447 4.9.4 Idiopathic Pulmonary Fibrosis, 448 4.9.5 Presbycusis (Age-Related Hear Loss), 448 References, 448 List of Abbreviations 479 Index 493

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Book SynopsisAs one grows older, one climbs with surprising strides. George SandSo what if you''re turning 70? After all, with age comes wisdom and a lot of perks. The early years of retirement can be more fruitful, fun-packed and adventurous than any that went before, with the time and space to explore the countless possibilities that life still holds. But what should you do and where should you start? Whether learning how to play the guitar, or writing that novel you''ve always had in you - don''t just kick back in your armchair and let the golden years pass you by. There is a big, wide world out there.This book will help you think positively, with things like this to look forward to:- Expand your horizons - if you want to get into surfing, go for it- Make a list of your top ten films and find the time to watch them- While you''re out on the town, test the bartender''s cocktail expertise- You''ve spent a lifetime learning. Put it good use and enter local quiz competitions

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Book Synopsis''Age is irrelevant, unless you happen to be a bottle of wine'' Joan CollinsKeren Smedley is passionate about altering outdated stereotypes about age and helping people to change their beliefs and attitudes to ageing. As a professional life coach - for Saga among other organizations - she has been asked every kind of question you could imagine, and some you couldn''t, about the uncertainties and problems of today''s baby boomer. Whether it''s about sexuality, money, relationships, health, friends, planning for the future, the best selection of those questions is contained here in WHO''S THAT WOMAN IN THE MIRROR? You will be impressed by the wisdom of the answers - and the endless variety of the questions. Like an extended problem page for baby boomers, this book will inform as it entertains.

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Book SynopsisIn addition, each chapter includes a new section entitled describing clinical applications.Trade ReviewA forward-thinking contribution to the field of dementia and is commendable for its goal of striving beyond overly simplistic, formulaic conventions. It would be well placed on the library shelf of the curious and contemplative cognitive clinician. -- Daniel Kaufer, M.D. New England Journal of Medicine A major contribution to dementia research... An excellent reference text for those exploring both the uncharted areas of research and some of the clinical aspects of dementia. -- Matthew Robillard, MD Canadian Journal of Psychiatry A valuable addition to our understanding of the conditions that erode our memory. -- Frances R. Frankenburg, M.D. American Journal of Psychiatry 2005 Timely publication... Stimulating and thorough coverage. -- Mark Walterfang International Psychogeriatrics 2004Table of ContentsContents:List of Contributors Acknowledgments List of Abbreviations IntroductionPART ONE: Background, Concepts, and Diagnostics1. Boundaries between Normal Aging and Dementia: Perspectives from Neuropsychological and Neuroimaging Investigations 2. The Spectrum of Dementias: Construct and Nosologic Validity 3. Diagnostic Procedures for Dementia PART TWO: Alzheimer Dementias4. The Neuropathology of Alzheimer Dementia 5. Neural Inflammatory Mechanisms in Alzheimer Syndrome 6. Clinical Subgroups of Alzheimer Disease 7. Progressive Aphasia, Frontotemporal Dementia and Other "Focal Dementias" 8. "Retrophylogenesis" of Memory in Dementia of the Alzheimer Type: A New Evolutionary Memory FrameworkPART THREE: Vascular Dementias and Subcortical Dementias9. Cortical and Frontosubcortical Dementias: Differential Diagnosis 10. Noninfarct Vascular Dementia: The Spectrum of Vascular Dementia and Alzheimer Syndrome 11. The Relationship of Hypertension to Vascular Dementia 12. Vascular Dementias and Alzheimer Disease: Differential Diagnosis 13. Acquired Immunodeficiency Syndrome Dementia ComplexPART FOUR: Depressive Dementias14. Depressive Dementia: A "Prepermanent Intermediate-stage Dementia" in a Long-term Disease Course of Permanent Dementia? 15. Depressive Dementia: Cognitive and Biological Correlated and Course of Illness 16. The Nondepressive Pseudodementias 17. Neurobiology of Major Depression in Alzheimer Disease 18. Approaches to the Treatment of Dementing Illness 19. The Spectra of the Dementias Index

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Book SynopsisShannon, Richard L. Sprott, Rosemarie Tong, Laurie ZolothTrade ReviewThis is a brilliant and useful book that summarizes much information from different points of view into a unified whole... So vibrant in its clarity,, so audacious in its thinking, it adds much to the luster of this remarkable book, one that deserves a wide readership. Doody's Review Service 2008 A comprehensive yet concise, simple-to-read synopsis of the issue involving modern biotechnology/aging research... Highly recommended. Choice 2009 A thought-provoking starting point for anyone interested in the varied and reciprocal implications of population aging and developments in biotechnology. -- Stephen J. Cutler, PhD Gerontologist 2009 An approachable... collection of essays -- Gareth Southwell Metapsychology 2009Table of ContentsPrefaceList of Contributors Part I: IntroductionChapter 1. Reality check: What Is Genetic Research on Aging Likely to Produce, and What Are the Ethical and Clinical Implications of Those Advances? Chapter 2. Meeting the Challenges of a Diverse Aging SocietyPart II: ImmortalityChapter 3. Immortality Through cloning? Reproduction, Regeneration, and the PosthumanChapter 4. The Transhumanist Movement: A Flawed Response to Aging and Its Natural ConsequenceChapter 5. Stem cell Research and InterventionChapter 6. The Ethical, Legal, and Social Implications of Antiaging TechnologiesChapter 7. Stem Cells and Aging: Quality and Quantity of Life in an Unjust World Part III: CentenariansChapter 8. Centenarians and GeneticsChapter 9. What Can We learn From Centenarians? Chapter 10. A Developmental Perspective on Aging and Genetic Technology: A Response to Studies of CentenariansPart IV: Genetic TestingChapter 11. Genetic Testing for Alzheimer Disease: The REVEAL Study Chapter 12. The Implications of Genetic testing for Alzheimer DiseaseChapter 13. Genetic Susceptibility to Alzheimer DiseaseChapter 14. Psychological Issues in Genetic TestingChapter 15. Genotype, Phenotype, and Primary care: Why the New Genetics Technology Is Not Ready for Primary Care Part V: Ethical and Social PerspectivesChapter 16. Genetics, Aging, and Primary care: Ethical Implications for CliniciansChapter 17. Aging, Genetics, and Social JusticeChapter 18. The Ethics of Aging: Question of Ends at the End of LifeChapter 19. A Lonely New World—or Me, Myself, and IIndex

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Book Synopsis This authoritative reference work contains more than 300 entries covering all aspects of the multi-disciplinary field of adult development and aging Brings together concise, accurate summaries of classic topics as well as the most recent thinking and research in new areas Covers a broad range of issues, from biological and physiological changes in the body to changes in cognition, personality, and social roles to applied areas such as psychotherapy, long-term care, and end-of-life issues Includes contributions from major researchers in the academic and clinical realms 3 Volumes www.encyclopediaadulthoodandaging.comTrade Review"This three-volume encyclopedia set includes a diversity of topics focused on the understanding the physical, mental, and social aspects of aging adults.....the set will serve well as a desk reference for professionals and is an up-to-date addition to academic library reference collections." (Choice Connect 2016)Table of ContentsVolume IAlphabetical List of Entries viiThematic List of Entries xiiiAbout the Editors xixContributors xxiiiIntroduction xcviiAdulthood and Aging A–Volume IIAdulthood and Aging –Volume IIIAdulthood and Aging –ZIndex

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Book SynopsisMental Health, Intellectual Disabilities, and the Aging Process Edited by Philip W. Davidson, Vee P. Prasher and Matthew P. Janicki This book is the third in a series with the International Association for the Scientific Study of Intellectual Disabilities (Series Editor: Matthew P. Janicki).Table of ContentsOverview of Aging, Emotional Health and Behaviour. Section I: Prevalence and Diagnosis. Prevalence of Mental, Behavioural and Neurobehavioral Disorders among Older People with Intellectual Disabilities. Psychopathology and Older Age. General Etiological Issues. Assessment of Behavioural and Psychiatric Disorders. Depression in Adults and Aging Individuals with Intellectual Disabilities. Cognitive Decline and Aging. Behavioural and Psychiatric Overlays from Physical and Medical Conditions. Emotional Health and Aging in Adults with Down Syndrome. Section II Treatments and Interventions. Psychotherapy and Other Psychological Interventions. Aging-Related Behavioural Interventions. Psychotropic Medications. Dynamics of Bereavement and Grief Reactions. Section III Service System Issues. Community Mental Health and Support Services: Planning Principles and Models. Prevention Strategies and Community Education. Future Directions and Challenges

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Book SynopsisLook 15 years younger in 2020 with Eva Fraser''s easy facial workout ___________ Facial Yoga is THE non-surgical way to achieve a facelift - and help you look 15 years younger! ''Facial exercises may significantly reduce signs of ageing'' New York TimesIn the ORIGINAL facial fitness classic, Eva Fraser shows you how straightforward exercises can help eliminate dark circles, firm your jaw line, tone your neck, plump cheeks and so much more . . . leaving your skin with a natural, youthful glow. For nearly 40 years, Eva Fraser has been practicing her facial workout techniques - and the results are remarkable. The premise is simple: the muscles in your face, if left inactive, will become as saggy as those in any other part of your body. In order to tone them up, they need to be exercised. This book includes information on why the face ages, how skin works and what can be done about it, as wTrade ReviewFacial exercises may significantly reduce signs of ageing * New York Times *

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Book SynopsisThe essential guide to making sure you have a fabulous later life.You're likely to live longer than you think. Today's fifty-year olds could have an astounding 36 or more years of life. What's your dream life for your later years? When We're 64 is a friendly, practical guide to preparing for what could be the best years of your life - from the essentials on work and how to fund retirement, to volunteering, where to live and what kind of housing you'll need. It covers how to stay healthy and still live a full life if you get a health condition and reveals how your attitude to ageing could actually increase your lifespan. There are sections on relationships with family and friends, as well as caring for older relatives and how to tackle loneliness. Packed with expert advice and new evidence and tips on how to age well, this route map will help you plan and prepare for the future.Trade ReviewAn easy to read excellent guide, full of practical advice to help prepare us for a happy and healthy older age. -- Diana Moran * Green Goddess *A very important book for the next phase in people’s lives -- Professor Sir Muir GrayThis uplifting playbook is essential preparation for later life. Grounded in the latest research, it guides us through all the practical steps needed to face the future positively – and that’s the key to health and happiness in our sixties and beyond. -- Celia Dodd * author of Not Fade Away *A new stage of life is emerging as longer lives give us extra years between middle age and old age. When We’re 64 provides a guide to navigating the new opportunities that lie ahead. -- Andrew Scott * co-author of The 100-Year Life *An indispensable book by a leading anti-ageing expert * Mail on Sunday *An easy-to-read guide to a great later life, including advice to follow (from your 50s) to keep healthy and happy. * Woman's Weekly *This cheery book is a practical guide to making later life look and feel fab. It covers a range of topics from pensions and volunteering, to housing and loneliness. If you're nervous about the coming years – for you or a loved one – prepare to feel fully reassured. * Top Sante *A brilliant, friendly, practical guide to a better later life. -- Aggie MacKenzie * My Weekly *The ultimate practical guide to later life… filled with expert advice and new evidence and tips on how to age well, an eminently readable, light-hearted look at how to plan and prepare for what could be the best years of your life * Celebrity Angels *Table of ContentsIntroduction 1 The ‘new’ issue of old age 2 How are you ageing? 3 Are you an old age ageist? 4 Funding it 5 Nice work if you can get it 6 Fit as a fiddle or good enough health? 7 Where you’ll live 8 What your home should look like 9 Friends, family and other folk 10 Make change now Top Resources Acknowledgements Bibliography Index

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Book SynopsisMove better, get stronger, and feel great with yoga no matter what your age.In Stay Young with Yoga, yoga teacher Nicola Jane Hobbs shows you how to stay flexible, energized and pain-free in your 40s, 50s, 60s and beyond. Whether you want move better, get stronger, ease aches and pains, or simply feel fitter and healthier, Nicola guides you through over 70 simple poses and 20 easy-to-practice sequences, with variations and modifications so you can choose poses and sequences that suit you. With routines designed to fit in with your lifestyle, including morning sequences, desk stretches, de-stress routines, sequences to practice after gardening, housework, and in front of the TV, as well as routines for pain-free movement, workouts for strength and fitness, and routines to support your other hobbies like golf, tennis, and dancing, Stay Young with Yoga will give you the tools to get stronger, fitter and healthier whatever your age.Table of ContentsIntroduction 1 The Science 2 The Yoga Practice 3 Making Yoga Work For You 4 The Poses 5 The Sequences Appendices Final Words Acknowledgements Research References Index

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Book SynopsisThis book explodes some myths about aging and reveals ten personal development tools to help us change our perspective to bolster emotional and psychological resilience in later life. In this handbook Guy Robertson offers ten steps that anyone can take to improve the likelihood of living a happy and satisfying life in old age. Research shows that how we think about ageing can have a very significant impact on our health and well-being in later life. Concentrating on the psychological and emotional aspects of ageing, these clear practical exercises will empower the reader to engage in a program of personal change. Getting older is not all bad! Indeed the reality is much more positive than many of us could imagine.Trade ReviewThis insightful and practical book encourages us to confront the toxic effects of ageism on our wellbeing as we move through life. The Ten Steps of Positive Ageing offers simple, powerful ways to build a more accurate narrative and take that resilience and power out into the world. -- Ashton Applewhite * author of This Chair Rocks: A Manifesto Against Ageism *I really like this book: well-researched, practical and realistic, it embraces the ageing process with a lovely thoughtful optimism, making valuable suggestions about how readers can reach this point themselves. Guy Robertson is a splendid tour guide for the journey into later life. -- Anne Karpf * author of How to Age *An indispensable guide to planning positively for a happy and fulfilling old age. Wise, inspirational and thought-provoking. -- Celia Dodd * author of Not Fade Away: How to Thrive in Retirement *This book will help you become more positive and live longer, better. -- Muir Gray * author of Sod 70! *Relaxed, jargon-free and engaging … helpful and accessible -- Mervyn Eastman * co-founder of Change Agents: The Older Peoples' Cooperative Collective *If you’re feeling even slightly down about getting older, The Ten Steps of Positive Ageing is the antidote. Full of detailed and ‘do-able’ advice, Guy Robertson’s book gives you more control over your ageing than you ever imagine you could have. This book turns the myth of ageing as decline completely on its head and shows us how to choose a positive and fulfilled later life. The Ten Steps of Positive Ageing is literally life-changing! -- Louise Ansari * The Centre for Ageing Better *Our ageing and our longer lives are too often seen as problems rather than opportunities. It is good to have a book that makes the ‘case for the defence’. In his new book The Ten Steps of Positive Ageing, Guy Robertson sets out a balanced view of the plusses and minuses of ageing. -- Baron Filkin (CBE) * former Chair of the Centre for Ageing Better *Offers advice on how to weather the passing of time and transform yourself into a proper golden oldie * The Scotsman *Table of ContentsIntroduction Understanding age and ageing What is positive ageing? The Ten Steps Step 1: Face up to your mortality Step 2: Fact-check the fake news about ageing Step 3: Watch your attitude Step 4: Safeguard your convoy Step 5: Adopt a mindful outlook Step 6: Broaden and build your wellbeing Step 7: Learn from your past Step 8: Establish what is most important to you Step 9: Create a vision for a new later life Step 10: Build your resilience Afterword Positive ageing playlist Acknowledgements Biography References Index

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Book SynopsisAlthough books exist on the evolution of aging, this is the first book written from the perspective of again as an adaptive program. It offers an insight into the implications of research on aging genetics, The author proposes the Demographic Theory of Senescence, whereby aging has been affirmatively selected because it levels the death rate over time helping stabilize population dynamics and prevent extinctions.Table of ContentsIntroduction. Hormesis. The Diverse Demography of Aging. Aging is not caused by accumulated damage. Three Prevailing Theories, and Their Failings. Aging is Very Old. Population Control. How Might Aging Have Evolved as an Adaptation? Implications and Directions. A New Paradigm for Medical Research.

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Book Synopsis'A stunner ... If you haven't got this book in your house, I don't know why' Chris Evans 'A startling wake-up call . . . Writing with the vim of a Bill Bryson and the technical knowledge of a scientist, Steele gives us a chance to grasp what's at stake' Independent 'An exhilarating journey . . . Steele is a superb guide' Telegraph 'A fascinating read with almost every page bursting with extraordinary facts . . . Read it now' Mail on Sunday Ageless is a guide to the biggest issue we all face. Ageing – not cancer, not heart disease – is the world's leading cause of death and suffering. What would the world be like if we could cure it? Living disease-free until the age of 100 is achievable within our lifetimes. In prose that is lucid and full of fascinating facts, Ageless introduces us to the cutting-edge research that is paving the way for this revolution. Computational biologist Andrew Steele explains what occurs biologically as we age, as well as practical ways we can slow down the process. He reveals how understanding the scientific implications of ageing could lead to the greatest discovery in the history of civilisation – one that has the potential to improve billions of lives, save trillions of dollars, and transform the human condition.Trade ReviewA tour de force of anti-ageing science * The Times *Steele is a superb guide to the wilder fringes of real medicine . . . He understands that ageing is an experience to be lived meaningfully and fully, as well as a fascinating medical problem to be solved. His vision is very tightly controlled . . . I heartily recommend Ageless. It’s modest in scope, and generous in detail. It’s an honest and optimistic contribution * Telegraph *Ambitious and energetic . . . Give[s] a startling round-up of the biological factors that make us age and the emerging techniques to tackle them . . . Writing with the vim of a Bill Bryson and the technical knowledge of a scientist, Steele gives us a chance to grasp what’s at stake in this dazzling, daunting age where big data meets human biology * Independent *Ageless employs a scientific vocabulary – autophagy, amyloids, adducts and countless other specialised terms abound. But the book is nevertheless accessible, its style chatty and engaging . . . This is an enthralling book . . . Ageless is a rich and exciting exploration of that surprisingly intriguing topic we’d rather not talk about: old age * Irish Times *A fascinating read with almost every page bursting with extraordinary facts . . . Steele is not a crank or a snake-oil salesman. He’s not a ‘wellness’ YouTuber. He doesn’t work for Goop. He’s a biologist . . . We can take what he says seriously * Mail on Sunday *There are some incredible revelations in this book. The science is fascinating . . . What Steele says is both revolutionary and important – life-changing in the true sense of the word. His thinking is bold, visionary, utopian * The Herald *A fascinating book delivering an education into the ageing process and an insight into the possibilities of the future -- Tim LovejoyAn immensely important book. Steele surveys the biology of human ageing, as well as the cutting-edge research on how to prevent it. The first person to achieve immortality may already have been born. Is it you?! -- Professor Lewis Dartnell, author of 'Origins'This is an essential book for anyone interested in the fast-developing science of longevity -- Jim Mellon, Chairman of JuvenescenceAgeless is a fascinating, stimulating and pleasingly practical guide to the science of ageing and how we might be able to bend the arrow of biological time to improve our health -- Kat Arney, author of 'Rebel Cell: Cancer, Evolution and the Science of Life'Few issues can be more important for our future than ensuring we age as well as possible. Ageless explains the extraordinary achievements and promise of current scientific research around longevity. Read it and prepare to think differently about your future -- Andrew Scott, Professor of Economics, London Business School and co-author of 'The 100-Year Life'In his book Ageless, Andrew Steele describes how the field of ageing biology moved from hope to promise. This is a masterful roadmap for interested lay people, scientists at large and also geroscientists like myself – I was surprised how much I learned -- Nir Barzilai, founding director of the Institute for Aging Research at Albert Einstein College of Medicine of Yeshiva UniversityA fascinating look at how scientists are working to help doctors treat not just one disease at a time, but the ageing process itself, helping us all to lead longer, healthier lives -- Sanjay Gupta, Associate Chief of the Neurosurgery Service at Grady Memorial Hospital in Atlanta, Georgia, Associate Professor of Neurosurgery at the Emory University School of Medicine and Chief Medical Correspondent for CNNA rigorous yet enjoyably readable, spellbinding tale -- George Church, Professor of Genetics, Harvard Medical School

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Book SynopsisA practical guide to how we can positively adapt to a changing world, from the internationally bestselling authors of The 100-Year Life ‘The London Business School professors Andrew J. Scott and Lynda Gratton have been predicting how society must adapt for years. Now they have a post-pandemic road map for us all’ Sunday Times Smart new technologies. Longer, healthier lives. Human progress has risen to great heights, but at the same time it has prompted anxiety about where we’re heading. Are our jobs under threat? If we live to 100, will we ever really stop working? And how will this change the way we love, manage and learn from others? One thing is clear: advances in technology have not been matched by the necessary innovation to our social structures. In our era of unprecedented change, we haven’t yet discovered new ways of living. Drawing from the fields of economics and psychology, Andrew J. Scott and Lynda Gratton offer a simple framework based on three fundamental principles (Narrate, Explore and Relate) to give you the tools to navigate the challenges ahead. The New Long Life is the essential guide to a longer, smarter, happier life.Trade ReviewA manifesto for better later years * Financial Times *Wonderful . . . This thought-provoking book is a must-read -- Daron Acemoglu, Institute Professor, Massachusetts Institute of Technology and author of 'Why Nations Fail'‘The London Business School professors Andrew J. Scott and Lynda Gratton have been predicting how society must adapt for years. Now they have a post-pandemic road map for us all * Sunday Times *In this fresh and striking book, Scott and Gratton address the central question of our age: how to achieve human flourishing at a time of radical new technology and longer lives. The optimism oozes out, as unlike most attempts to tackle this question, they never forget that, done right, new technology and longer lives are forces for good -- Rt Hon Matt Hancock, UK Secretary of State for Health and Social CareThe combination of rapid technological change and ageing are causing deep anxiety about the future. Gratton and Scott show us how social ingenuity by individuals, employers and governments can turn sources of fear into sources of hope -- Dame Minouche Shafik, Director, London School of Economics and Political ScienceStimulating, insightful and inspirational. This book is an essential work on how longevity and technology affect us all. Read it to not only learn about ageing and robots, but also how to use that knowledge to positively transform our lives -- Linda Yueh, author of 'The Great Economists: How Their Ideas Can Help Us Today'A fascinating book grappling with a critical topic: how to embrace technological change and longevity. A recommended read for business leaders with the job of nurturing a happy and productive workforce -- Anne Richards, CEO, Fidelity InternationalBrilliant, timely, original, well written and utterly terrifying -- Niall Ferguson, Praise for 'The 100-Year Life'A fascinating and thought-provoking book. A brilliant read for individuals, but should be mandatory reading for our politicians -- Shirley Cramer CBE, Chief Executive Officer, Royal Society for Public Health, Praise for 'The 100-Year Life'

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Book Synopsis'Some people improve mentally with age - here's how you can be one of them.' Mail on Sunday'More than a game-changer, this book's a no-brainer for anyone who wants to optimise their brain.' Piers MorganWith a new chapter on Covid and the Brain, this is the definitive guide to keeping your brain healthy for a long and lucid life, by one of the world's leading scientists in the field of brain health and ageing.The brain is our most vital and complex organ. It controls and coordinates our actions, thoughts and interactions with the world around us. It is the source of personality, of our sense of self, and it shapes every aspect of our human experience.Yet most of us know precious little about how our brains actually work, or what we can do to optimise their performance. Whilst cognitive decline is the biggest long-term health worry for many of us, practical knowledge of how to look after our brain is thin on the ground.In this ground-breaking new book, leading expert Professor James Goodwin explains how simple strategies concerning exercise, diet, social life and sleep can transform your brain health paradigm, and shows how you can keep your brain youthful and stay sharp across your life. Combining the latest scientific research with insightful storytelling and practical advice, Supercharge Your Brain reveals everything you need to know about how your brain functions, and what you can do to keep it in peak condition.Trade ReviewMore than a game-changer, this book's a no-brainer for anyone who wants to optimise their brain. * Piers Morgan *Some people improve mentally with age - here's how you can be one of them. * Mail on Sunday *Little things you do every day can help ensure your brain is fit and healthy - and it's never too late to start, says ageing expert James Goodwin. * New Scientist *The secrets to a better brain. Goodwin unwraps the mystery of the brain - and how to give it a boost so that you can keep on enjoying life. * Top Sante *A remarkable book, which turns cutting-edge science into simple strategies for a healthier life that all of us should use. * Phillip Polakoff *

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Book SynopsisResearch suggests that only 10-30% of our lifespan is determined by our genetics. This means that the vast majority of how we age is directly related to choices we make everyday - how and what we eat, exercise and sleep quality, to name a few. So, while ageing itself may be inevitable, what if there were a way to measure our biological age? And what if there were strategies to slow down, or even reverse, the ageing process?In True Age, Dr Morgan Levine gives us an insight into the cutting-edge developments in the science of aging and longevity and teaches us that through understanding our biological age, we can monitor and even control the process of ageing.True Age explores:- The concept of biological age and the methods now available to determine your own.- Types of foods likely to decrease our biological age - and which will age you prematurely.- What types of exercise are most effective for turning back the clock.- How much sleep we need and what other lifestyle patterns are most likely to help slow and reverse ageing.True Age will equip you with the tools you need to develop personal regimes, diets and routines specifically tailored to keep you looking - and feeling - as young as possible. Using her years of expert research in the field, Dr Levine will put you on the path to living a healthier and more proactive life.

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Book SynopsisAs an objective of human security, it is important to understand the social system and to make more appropriate policies for people based on the bio-psycho-social viewpoint of health advocated by the World Health Organization (WHO). For countries with increasingly large populations of older adults, aging-related disorders cause many social handicaps. A comprehensive approach for integrating not only medical, but also psychosocial and spiritual viewpoints is needed for better health policy planning.During a risky situation such as a major disaster, which can critically affect peoples lives, people should utilize their brains more fully in order to survive; i.e., to understand the situation around them, to make a proper judgment call, and to choose their behaviors. All of these approaches are associated with brain functions. Understanding the situation primarily requires the posterior part of the brain, especially the parietal lobe.Briefly, the occipital, temporal, parietal, and frontal lobes are related to visual, auditory, other sensory, and motor functions, respectively. Each lobe has primary and secondary areas: The former is associated with primary function, whereas the latter is related to association functions, which add meaning to the primary information. In particular, visual and auditory information should be fully integrated to understand the situation and make a judgment call, which is the function of the parietal lobe.Human Security: Social Support for the Health of an Aging Population Based on Geriatric Behavioral Neurology is meant to help readers understand the bio-psycho-social viewpoint and bioethics of social support for elderly people. The second aim is to understand the social support system and Quality of Life (QOL) for handicapped and elderly people. Especially, the long-term care insurance system for elderly people in Japan, which is a well-organized system to support well-being in the elderly, needs to be understood. Also, dementia is one of the important age-related disorders that can affect not only patients themselves, but also their families, community residents, and society. The third objective is to understand dementia and dementing diseases, not only from a medical perspective, but in terms of psychosocial and spiritual aspects. Following the Great East Japan Earthquake of 2011, various cases of weakness due to the disaster were analyzed. Most of them were previously assessed as a borderline condition between healthy and dementia. Therefore, it is important to routinely screen community residents for security.All risky situations such as a disaster should be treated internationally. The author recalls that one student told them that the Indonesian government faces difficulties in preparing for a disaster with a unified language. Indeed, more than 700 regional languages are spoken in Indonesias numerous islands. However, disasters do not select a language. The author is certain that there are some lessons from their history that have not been recorded in a common language. It is important to establish a network based not only on local culture and language, but also a global proposal based on a common language.The author hopes that young scientists in the next generation will have an integrated perspective and will apply science to human security worldwide.

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