Medical laboratory testing and techniques Books
National Academies Press Guide for the Care and Use of Laboratory Animals
Book SynopsisA respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: *Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. *Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. *Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, Table of Contents1 Front Matter; 2 1 Key Concepts; 3 2 Animal Care and Use Program; 4 3 Environment, Housing, and Management; 5 4 Veterinary Care; 6 5 Physical Plant; 7 Addendum: Guide for the Care and Use of Laboratory Animals Eighth Edition; 8 Appendices; 9 Appendix A: Additional Selected References; 10 Appendix B: U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training; 11 Appendix C: Statement of Task; 12 Appendix D: About the Authors; 13 Index
£28.05
Oxford University Press Oxford Handbook of Clinical and Healthcare
Book SynopsisThis handbook is a definitive, up-to-date, and succinct text covering the legislative requirements, scientific foundations, and clinical good practice necessary for clinical, academic, and healthcare research.Trade ReviewThe Oxford Handbook of Clinical and Healthcare Research packs a lot of information into a literally hand-sized ... book, with precise writing." * Norman M. Goldfarb, Journal of clinical research best practises *A unique handbook that covers all the stages of clinical research along with a clear description of the regulations / processes that current researchers need to comply with. This truly addresses a much needed gap in the various research handbooks. * Dr Puja Myles, Associate Professor Health Protection and Epidemiology; Nottingham University *Table of Contents1. Research - How and Why ; 2. Navigating Research Methods: Basic concepts in biostatistics and epidemiology ; 3. Navigating Research Methods: Quantitative and clinical / epidemiological methods ; 4. Navigating Research Methods: Qualitative methods ; 5. Navigating Research Methods: Evidence Based Medicine (EBM) ; 6. Navigating Research Methods: Critical ap-praisal ; 7. Navigating Research Methods: Clinical Audit ; 8. Setting the scene and ICH-GCP in clinical and healthcare research ; 9. Informed consent in a research setting ; 10. Ethics of clinical and healthcare research: general considerations, Mental Capacity Act, Human Tissue Act ; 11. Role and Responsibilities: Investigators and Research Team ; 12. Role and Responsibilities: Sponsor ; 13. Monitoring ; 14. Clinical Trial Design ; 15. Clinical Trial Protocols: Study Protocol ; 16. Data Capture Tools: Case Report Form (CRF) ; 17. Clinical Trial Supplies: IMPs ; 18. IMP Accountability ; 19. Safety Reporting ; 20. Data management ; 21. Research Project Management ; 22. Essential Documents ; 23. Archiving ; 24. Audits and Inspections ; 25. Fraud and Misconduct ; 26. Authorship ; 27. Publication process ; 28. Start-up toolkit: from funding an idea, through implementation, to achieving an impact
£34.19
Oxford University Press Histopathology Fundamentals of Biomedical Science
Book SynopsisHistopathology describes the processes and practices that are central to the role of the histopathologist within a functioning diagnostic laboratory, from pre-sampling to diagnosis to laboratory management.Trade ReviewIt is very simply and clearly written in language that is easy to understand for the non-specialist. It describes day-to-day histopathology lab practice with clarity and the case studies are very helpful to illustrate the applications of the techniques. * Susan Brooks, Oxford Brookes University *The strength of the book is its detail. The book contains information that is completely lacking from other histopathology books. Overall I think that it is a great textbook for biomedical students and academics. * Akis Karakesisoglou, Durham University *Any potential biomedical scientist with an interest in histopathology, and sound knowledge of the contents of this well- written and nicely-illustrated text together with appropriate practical experience would be well on their way to becoming a valuable member of the team that comprises the core of todays histopathology laboratory. The text will make a valuable addition to any library associated with laboratories performing histopathological techniques. * Judy Brincat, Histology Group of Victoria *Table of Contents1: Dr Guy Orchard, Mr David Muskett, Dr Anne Warren: What is histopathology? 2: Mr David Muskett: Fixation and specimen handling 3: Ms Vanda McTaggart, Dr Sue Pritchard, Dr Anne Warren: Data recording and histopathology dissection 4: Mr David Muskett: Routine staining, processing and embedding 5: Mr David Muskett and Dr Guy Orchard: Special stains 6: Dr Guy Orchard , Mrs Chantell Hodgson, Mr Brian Nation: Artefacts 7: Dr Guy Orchard and Mr Mohammad Shams: Mohs procedures 8: Dr Merdol Ibrahim and Dr Guy Orchard: Immunocytochemical techniques 9: Mr David Muskett, Dr Guy Orchard, Dr Anne Warren: Analytical immunocytochemistry 10: Dr Tony Warford and Dr Emanuela Volpi: In situ hybridization: concepts and applications 11: Mr Brendan O'Sullivan and Dr Phillipe Taniere: Molecular diagnostics: techniques and applications 12: Dr Phillipe Taniere: Molecular diagnostics in action 13: Dr Guy Orchard and Dr Sue Pritchard: Histopathology reporting 14: Dr Guy Orchard: Microscopy and digital pathology 15: Prof David Furness: Electron microscopy in diagnosis 16: Ms Ishbel Gall and Dr Mike Osborne: Mortuary practice 17: Ms Sue Alexandra and Ms Patricia Fernando: Essentials of laboratory management
£44.99
Oxford University Press Molecular Diagnostics
Book SynopsisOne of the most notable trends in biomedical science in recent years has been the increasing use of molecular techniques as part of the diagnosis of disease. As such, there is a growing need for students to understand the technological basis of molecular analysis and to have a comprehensive appreciation of their use in diagnosis. Combining coverage of molecular techniques with their application to diagnostic pathology, this book provides students with a thorough and up to date appreciation of the scope of molecular analysis, the principles of the technology used, and thematic diagnostic application. As part of the Fundamentals of Biomedical Science series, the book provides a unique blend of theory and practice, featuring a range of learning features to help students assimilate the information presented quickly and effectively. It will be relevant to undergraduate students on a wide variety of biomedical pathways, cutting across traditional discipline boundaries to provide a unified ovTable of ContentsIntroduction 1: Sample preparation 2: The molecular laboratory 3: Intact sample analysis 4: Homogenate sample analysis 5: Sequencing technologies 6: Molecular analysis and interpreting molecular data 7: Recent technical advances in molecular analysis 8: Haemopoietic diseases 1 - leukaemias 9: Haemopoietic diseases 2 - lymphoproliferative disorders 10: Breast cancer 11: Epithelial tumours and melanoma 12: Mesenchymal tumours 13: Pre-natal and neo-natal testing
£47.99
F.A. Davis Company Molecular Diagnostics Fundamentals Methods and
Book SynopsisMeet the challenges of this rapidly expanding field with a solid understanding of the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to practice in today's laboratories. The third edition of this popular resource encompasses microbiology, virology, genetics, oncology, and human identification.Table of Contents I. Fundamentals of Molecular Biology: An Overview 1. Nucleic Acids and Proteins 2. Gene Expression and Epigenetics II. Common Techniques in Molecular Biology 3. Nucleic Acid Extraction Methods 4. Resolution and Detection of Nucleic Acids 5. Analysis and Characterization of Nucleic Acids and Proteins 6. Nucleic Acid Amplification 7. Chromosomal Structure and Chromosomal Mutations 8. Gene Mutations 9. DNA Sequencing III. Techniques in the Clinical Laboratory 10. DNA Polymorphisms and Human Identification 11. Detection and Identification of Microorganisms 12. Molecular Detection of Inherited Diseases 13. Molecular Oncology 14. DNA-Based Tissue Typing 15. Quality Assurance and Quality Control in the Molecular Laboratory Appendices A. Study Questions Answers B. Answers to Case Studies Glossary Index
£66.60
F.A. Davis Company Clinical Immunology Serology
Book SynopsisIncludes coverage of external defenses and inflammation, human microbe relationships, bacterial virulence factors, the role of B and T cells in the adaptive immune response, the immune mechanisms involved in humoral antibody production and cell-mediated immunity, tumor markers, and immune mechanisms.Table of Contents I. Nature of the Immune System 1. Introduction to Immunity and the Immune System 2. Nature of Antigens and the Major Histocompatibility Complex 3. Innate Immunity 4. Adaptive Immunity 5. Antibody Structure and Function 6. . Cytokines 7. Complement System II. Basic Immunological Procedures 8. Safety and Quality Assessment 9. Principles of Serological Testing 10. Precipitation and Agglutination Reactions 11. Immunoassays 12. Molecular Diagnostic Techniques 13. Flow Cytometry and Laboratory Automation III. Immune Disorders 14. Hypersensitivity 15. Autoimmunity 16. Transplantation Immunology 17. Tumor Immunology 18. Immunoproliferative Diseases 19. Immunodeficiency Diseases IV. Serological and Molecular Diagnosis of Infectious Disease 20. Serological and Molecular Detection of Bacterial Infections 21. Spirochete Diseases 22. Serological and Molecular Diagnosis of Parasitic and Fungal Infections 23. Serology and Molecular Detection of Viral Infections 24. Laboratory Diagnosis of HIV Infection 25. Immunization and Vaccines Glossary Answer Key References Index
£78.30
Wolters Kluwer Health The Only Diagnostic Lab Book Youll Ever Need
Book Synopsis Concise, conversational, entertaining, and easy to use at any level of healthcare experience, The Only Diagnostic Lab Book You’ll Ever Need clarifies the when, where, why, and how of laboratory testing to help you make informed testing decisions and draw confident clinical conclusions. This approachable how-to guide focuses on the most common and clinically useful diagnostic tests and panels employed in everyday healthcare practice, regardless of specialty, making it the ideal introduction for medical, PA, nurse practitioner, and nursing students embarking on their healthcare education. Residents, fellows, and practicing clinicians will find many new insights and clinical pearls that can immediately improve their practice and teaching. Straightforward, clinically oriented coverage walks you through selecting and employing the right diagnostic tests from the thousands available. The result is an informative, engaging text that will help you hone your clinical reasoning and streamline your approach to ordering and interpreting lab tests in the clinical decision-making process. Abundant illustrations, tables, and flow charts highlight key concepts in selecting and interpreting diagnostic lab tests. Lively, lighthearted text gets right to the point without compromising clarity or detail. Discussions emphasize what the tests actually mean within the relevant clinical context, stressing understanding over memorization; you will know what to do next, what to avoid, and why.
£53.19
Oxford University Press Cytopathology Fundamentals of Biomedical Science
Book SynopsisCytopathology provides a wide-ranging overview of the microscopic study of normal and abnormal cells, showing how current visualization methods are used to study cell structure, and how early detection of abnormal cell pathology can lead to timely clinical interventions.Trade ReviewReview from previous edition The flow of information is excellent and the text is well-written... a good introductory text for undergraduates with an interest in cytology and for professionals in training. * Dr Lesley Walton, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University *Lucid, logical coverage of material, set out thoughtfully and supported by good illustrations and learning features that make the text student-friendly... a very useful undergraduate cytopathology textbook. * Dr Nicholas Vardaxis, Endeavour College of Natural Health *Clearly written, factual and concise. * Dr Patricia Gadsdon, FIBMS, School of Biological Sciences, Bangor University *Table of Contents1: Behdad Shambayati: Introduction: a glance at the past, a glimpse of the future 2: Andrew Evered & Behdad Shambayati: Preparation techniques 3: John Crossley & Beverley Crossley: The cervical screening process 4: Andrew Evered: Normal cervical cytology 5: Andrew Evered: Abnormal cervical cytology 6: John Crossley & Paul Cross: Quality issues in cervical screening and cytology 7: Andrew Evered: Diagnostic cytopathology 8: Behdad Shambayati: Cytology of urine 9: Behdad Shambayati: Serous effusions and peritoneal washings 10: Behdad Shambayati: Lower respiratory tract cytology 11: Behdad Shambayati: Fine needle aspiration cytology 12: Paul Cross & Behdad Shambayati: Cytology of head and neck 13: Stephen Blackman & Behdad Shambayati: Basic semen analysis 14: Behdad Shambayati: Cytology of the biliary tract and pancreas 15: Bruno Ping: Advances in cytopathology 16: Andrew Evered: Data analysis in cytopathology 17: Andrew Evered: Expertise in cytopathology
£55.09
Oxford University Press Transfusion and Transplantation Science
Book SynopsisBiomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible.The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposedfrom microbiology to cytopathology to transfusion science.The science of transfusion and transplantation demands a multifaceted understanding of immunology, haematology, andTrade ReviewReview from previous edition Excellent teaching material for those studying Biomedical Science. * Dr Stephen F. Hughes, University of Chester *There is a clear focus on practical application of the theory in the transfusion lab. * Dr Christine Shirras, Lancaster University *The main strength is the Biomedical Science perspective. The emphasis is on transfusion practice within the laboratory: the biochemistry backs up the practical applications, not the other way round as biochemistry texts often do. * Trish Procter, Keele University *Table of Contents1: Neil D. Avent: Introduction to Basic Immunology and Techniques 2: Neil D. Avent: Human Blood Group Antigens 3: Neil D. Avent: Haemolytic Disease of the Fetus and Newborn 4: Lionel Mohabir: Clinical Use of Blood Components 5: Catherine Hyland, John Barbara, and Lionel Mohabir: Microbiological Testing of Blood Donations 6: Geoff Lucas: Human Platelet Antigens (HPA) and Human Neutrophil Antigens (HNA) and their Clinical Significance 7: Malcolm Needs: Compatibility Testing and Adverse Effects 8: Malcolm Needs: Immune Mediated Red Cell Destruction 9: Neil D. Avent: Human Leucocyte Antigens (HLA) and their Clinical Significance 10: Ruth Morse and Saeed Kabrah: Haematopoietic Stem Cell Transplantation and Stem Cell Plasticity 11: Richard Lomas, Neil D. Avent, and Vehid Salih: Tissue Banking 12: Joan Jones: Quality Issues
£38.99
Oxford University Press An Introduction to Clinical Trials
Book SynopsisAn Introduction to clinical trials is a concise step-by-step guide to the principles and practices of clinical trials for those studying clinical trials or new to working on one. Clinical trials are critical to the progress of medicine and improving healthcare, as they evaluate whether new treatments and interventions work. They are also complex, multidisciplinary projects that integrate science, ethics, and legal requirements in the conduct of medical research. Starting with the research question, An Introduction to clinical trials explains study design, sample size determination, study set-up, study conduct, statistical analysis, and dissemination of the results. The book primarily focusses on randomised controlled trials as the ultimate clinical trial. It demystifies the terminology used in clinical trials research and presents the underlying scientific and statistical concepts. Real-life examples are used throughout to bring concepts to life.Written by an experienced medical statistician, An Introduction to clinical trials will benefit readers of all backgrounds, from postgraduate and medical students, trainee doctors and healthcare professionals to others working on clinical trials in a professional capacity. This book aims to help readers gain a fuller and more rounded understanding of clinical trials.Table of Contents1: What is a clinical trial? 2: Designing a clinical trial 3: Randomised controlled trials 4: Alternative randomised controlled trials designs 5: Choosing the sample size for a clinical trial 6: Setting up a clinical trial 7: Data collection and monitoring in a clinical trial 8: Conducting a clinical trial 9: Analysing a clinical trial 10: Reporting and disseminating the findings of a clinical trial
£37.99
Elsevier Health Sciences Basic Applied Concepts of Blood Banking and
Book Synopsis
£74.69
Cambridge University Press Manual of Intracytoplasmic Sperm Injection in
Book SynopsisFor around half of the couples who have trouble conceiving the cause of infertility is sperm-related. Intracytoplasmic sperm injection (ICSI) is the most common and successful treatment for male infertility. Here, the pioneers for the technique, along with authorities in the field, describe the underlying science of ICSI and other micromanipulation techniques. Practical advice for performing the techniques is covered in depth, including sperm selection, laser-assisted ICSI, and the use of piezo in ICSI. Examining the safety of ICSI in animal models as well as the impact of ICSI on the health and well-being of the children conceived through the procedure is discussed. This manual is an essential resource for clinical embryologists and laboratory personnel wishing to refine or develop techniques and improve outcomes.Table of ContentsForeword Zev Rosenwaks; 1. In-vitro fertilization and micromanipulation: The history that changed the treatment of male factor infertility Jacques Cohen; 2. Development of ICSI in human assisted reproduction Stephanie Cheung, Alessandra Parrella, Philip Xie, Sherina Lawrence, Mounia Haddad, Derek Keating, Zev Rosenwaks and Gianpiero D. Palermo; 3. Current ICSI applications and clinical outcomes Derek Keating, Stephanie Cheung, Philip Xie, June Wang, Zev Rosenwaks and Gianpiero D. Palermo; 4. Rescue ICSI of IVF failed-fertilized oocytes Carly Barber, Vivian Nguyen, Alexandrea Ramsey and Zsolt Peter Nagy; 5. High-magnification sperm selection before ICSI Pierre Vanderzwalmen, Barbara Wirleitner, Guy Cassuto, Romain Imbert and Maximillian Murtinger; 6. Laser-assisted ICSI Roberta Maggiulli, Simona Alfano, Erminia Alviggi, Gemma Fabozzi, Danilo Cimadomo, Filippo Maria Ubaldi and Laura Rienzi; 7. Piezo: The add-on to standardize ICSI procedure Tetsunori Mukaida, Kenichiro Hiraoka, Hideaki Watanabe, Kiyotaka Kawai and Csaba Pribenszky; 8. Artificial oocyte activation after ICSI Thomas Ebner; 9. Health of children born after Intracytoplasmic Sperm Injections (ICSI) Shahad Sabti and Alastair G. Sutcliffe; 10. Examining the safety of Intracytoplasmic Sperm Injection (ICSI) using animal models Laura Hewitson; 11. Cellular and molecular events after ICSI in clinically relevant animal models Lauren Hamilton, Richard J. Oko and Peter Sutovsky; 12. Micromanipulation, microinjection microscopes and systems for ICSI Steven D. Fleming; 13. Automation techniques and systems for ICSI Changsheng Dai, Zhuoran Zhang, Guanqiao Shan and Yu Sun; 14. Germline nuclear transfer technology to overcome mitochondrial diseases and female infertility Mao-Xing Tang, Annekatrien Boel, Paul Couke and Björn Heindryckx; 15. Nuclear transfer technology and its use in reproductive medicine Pasqualino Loi, Marta Czernik, Luca Palazzese, Pier Augusto Scapolo, Helena Fulka and Josef Fulka Jr; 16. The prospects of infertility treatment using 'artificial' eggs Katsuhiko Hayashi; Index.
£39.89
IGI Global Metaverse Applications for Intelligent Healthcare
Book Synopsis
£296.40
Jaypee Brothers Medical Publishers Clinical Biochemistry
Book SynopsisTable of ContentsSECTION 1: BASIC CHEMISTRY SECTION 2: FUNDAMENTALS OF BIOCHEMISTRY SECTION 3: CLINICAL BIOCHEMISTRY Index
£999.99
Springer Verlag, Singapore A Practical Guide to Pharmacological
Book SynopsisPharmacological biotechnology is applied to and used to study drug development, working mechanisms, diagnosis, and therapies. This textbook covers the whole range of experiments related to pharmacology. It also contains basic laboratory safety guidelines along with the basic calculations and formulas used in a laboratory. Each chapter starts with an introduction/theory into the basic approach followed by detailed methods sections with easy-to-follow protocols and comprehensive troubleshooting, calculations and possible questions for examination. The target group is researchers who are studying pharmacological biotechnology in the laboratory.Table of ContentsPart1.Introduction.- 1.1 Rules of laboratory safety in a pharmacology laboratory.- 1.2 Commom instruments and their uses used in a pharmacology laboratory.- Part2.General aspects of Pharmacology laboratory.- 2.1 Safety and Risk assessment.- 2.2 Use and Handling of laboratory animals.- 2.3 Experimental design.- 2.4 Essential statistics.- 2.5 Cumulative Dose Response Curve.- 2.6 Toxicology.- 2.7 Basic instruments and techniques in Pharmacology Laboratory .- Part3.Isolated tissues and organs.- 3.1 Basic instruments used for isolated tissue experiments.- 3.2 Organ baths.- 3.3 Smooth muscle preparations.- 3.4 Skeletal muscle preparations.- 3.5 Cardiac muscle preparations.- Part4.Isolated tissues for screening of drugs.- 4.1 Evaluation of antidiabetic agents.- 4.2 Evaluation of antidepressants.- 4.3 Evaluation of antihypertensive agents.- 4.4 Evaluation of antiulcer agents.- 4.5 Evaluation of hepatotoxicity.- 4.6 Evaluation of Antioxidant agents.- 4.7 Evaluation of local anaesthetics.- Part5.Genotoxicity and Toxicological studies.- 5.1 The Mouse Lymphoma Assay.- 5.2 The Comet Assay.- 5.3 In vitro Genotoxicity assay.- 5.4 In vitro Teratogenicity Testing.- 5.5 Histopathological studies of animal tissues.- 5.6 Drug poisoning.- Part6.Experimental Animal studies.- 6.1 Pyrogen testing.- 6.2 Collecting blood from mice.- 6.3 Studies on different parameters of blood.- 6.4 Experiment on central nervous system.- 6.5 Evaluation on cardiovascular system.- 6.6 Experiments on GI tract.- Part7.Clinical trials.- 7.1 Clinical Pharmacology and its genesis.- 7.2 National and International agencies and their role in Clinical pharmacology.- 7.3 Stages in drug development and clinical trials.- 7.4 Ethics in Clinical research.- 7.5 Safety assessment in Clinical trials.- Part8.IPR and ethics in animal studies.- 8.1 Intellectual property rights and its different categories.- 8.2 Importance of IPR in drug development.- 8.3 Patenting cells, cell lines and animals.- 8.4 Ethics in laboratory animal studies .- 8.5 Risk assessment and management.- 8.6 Good laboratory practices.
£999.99
Jessica Kingsley Publishers Common Laboratory Tests Used by TCM
Book SynopsisTraditional Chinese Medicine (TCM) practitioners need to have an understanding of Western medical testing to recognize when laboratory tests are required and to interpret test results that are brought to them by patients. This book is an essential reference for the TCM classroom and clinic that teaches how to use and understand conventional lab testing in the treatment and referral of patients.Focusing on symptoms that commonly present in TCM practices, the book groups the lab tests by diseases or systems. Within each chapter are TCM case studies and perspectives, as well as multiple choice quizzes that test the reader's knowledge. Co-written by a doctor of Western medicine and an acupuncture physician, the book aims to familiarize TCM practitioners with the terminology and methodology of lab tests, bridging the gap between Eastern and Western schools of medicine and promoting an integrative approach to improve the overall care of the patient.Trade ReviewCommon Laboratory Tests Used by TCM Practitioners should be in every practitioner's office, every school library and part of acupuncture programs. The patient expects it. Society needs it. The book is arranged by disease and system. This approach is enhanced for learners with clear and pertinent background information which services the acupuncturist's needs perfectly. -- William R. Morris, PhD, DOAM, President, AOMA Graduate School of Integrative Medicine, Austin, TexasDoctors of TCM in China include two years of modern medical sciences as part of their training. They routinely order blood tests in the clinic to help with differential diagnosis, as well as monitoring the patient's prognosis using Chinese herbal medicine. As TCM practitioners in the West treat complicated internal disorders, it is important for them to understand conventional blood tests from other doctors, as well as order their own tests. Doctors Banerjee and Captain have written an extraordinary and thorough training manual on the use of common lab tests in a TCM practice. It is destined to become a standard text on the subject in our schools and clinics. -- Jake Paul Fratkin, OMD, L.Ac, author of Essential Chinese FormulasTable of ContentsPreface. 1. Complete Blood Count (CBC). 2. Hemoccult. 3. Kidney and Urine. 4. Electrolytes. 5. Glucose Metabolism and Diabetes Mellitus. 6. Liver Function. 7. Lipids. 8. Thyroid and Endocrinology. Practice Questions. Further Reading. Glossary.
£15.99
Cambridge University Press Multiparameter Flow Cytometry in the Diagnosis of Hematologic Malignancies
a huge range and FREE tracked UK delivery on ALL orders.
£108.00
American Society for Microbiology Clinical Microbiology Procedures Handbook,
Book Synopsis
£337.50
R F Hoke Phlebotomy
£17.09
Elsevier Science Publishing Co Inc Boormans Pathology of the Rat
Book SynopsisSuitable for researchers across science and medicine using rat models in the laboratory setting, this book offers an added emphasis on the Sprague-Dawley and Wistar rat strains, in line with research across academia, government and industry.Table of ContentsSection I: Digestive System Section II: Liver and Exocrine Pancreas Section III: Urinary Tract Section IV: Nervous System and Special Sense Organs Section V: Musculoskeletal System Section VI: Integumentary System Section VII: Mammary Gland Section VIII: Respiratory Tract Section IX: Immune System Section X: Bone Marrow Section XI: Female Reproductive Tract Section XII: Male Reproductive System Section XIII: Circulatory System Section IIV: Endocrine System Section IX: Historical Data
£179.10
Elsevier Health Sciences Laboratory Tests and Diagnostic Procedures
Book SynopsisCovers over 900 lab tests and diagnostic procedures in all. This title provides alphabetical list of hundreds of diseases, conditions, and symptoms, including the tests and procedures most commonly used to confirm or rule out a suspected diagnosis. It presents key information on virtually every laboratory and diagnostic test available.Table of ContentsHow to Use This Book Part I: Diseases, Conditions, and Symptoms Part II: Laboratory Tests and Diagnostic Procedures Appendix A: Reportable Diseases Appendix B: Informed Consent for Genetic Testing Bibliography
£41.79
Elsevier Health Sciences Dacie and Lewis Practical Haematology
Book SynopsisTrade Review"It remains the worldwide standard in laboratory haematology and no haematologist should be without it!" "This is an excellent book for new learners or for experienced practitioners wanting an update/refresher. If you want a basic book covering all aspects of laboratory and clinical hematology, this is the one for you. If you are a student, this is a must have." -Valerie L. Ng, PhD MD (Alameda County Medical Center/Highland Hospital) Doody's Score: 94 - 4 Stars!Table of Contents1 Collection and handling of blood 2 Reference ranges and normal values 3 Basic haematological techniques 4 Preparation and staining methods for blood and bone marrow films 5 Blood cell morphology in health and disease 6 Supplementary techniques including blood parasite diagnosis 7 Bone marrow biopsy 8 Molecular and cytogenetic analysis 9 Iron deficiency anaemia and iron overload 10 Investigation of megaloblastic anaemia: cobalamin, folate and metabolite status 11 Laboratory methods used in the investigation of the haemolytic anaemias 12 Investigation of the hereditary haemolytic anaemias: membrane and enzyme abnormalities 13 Acquired haemolytic anaemias 14 Investigation of variant haemoglobins and thalassaemias 15 Erythrocyte and leucocyte cytochemistry 16 Immunophenotyping by flow cytometry 17 Diagnostic radioisotopes in haematology 18 Investigation of haemostasis 19 Investigation of a thrombotic tendency 20 Laboratory control of anticoagulant, thrombolytic and antiplatelet therapy 21 Blood cell antigens and antibodies: erythrocytes, platelets and neutrophils 22 Laboratory aspects of blood transfusion 23 Approach to the diagnosis and classification of blood cell disorders 24 Laboratory organisation, management and safety 25 Quality assurance 26 Haematology in under-resourced laboratories
£71.99
Cambridge University Press Behavioral Genetics of the Mouse Volume 1 Genetics of Behavioral Phenotypes
Book SynopsisA comprehensive overview of the genetics of naturally occurring variation in mouse behaviour, this book provides the baseline information that is essential to designing experiments and interpreting results in this field. It offers an easy entrance into the extensive literature and will prove valuable to specialists and students alike.Trade Review'This first volume is a much-needed reference text on the behavioral genetics of the mouse. I am looking forward to the subsequent volumes and expect that together they will provide a panoramic view of the field. Such a series of manuals will be invaluable to students, scientists, and scholars aiming to master the 'beauties' of mouse behavior.' Silvia Mandillo, Genes, Brain and Behavior'Behavioral Genetics of the Mouse represents a good effort to implement the knowledge of mouse behavior and a good guide for both students and senior researchers.' Enrico Alleva, Ann Ist Super SanitàTable of ContentsContributor list; Part I. General: 1. Current status of the field W. E. Crusio and R. T. Gerlai; 2. Natural neurobiology and behavior of the mouse: relevance for behavioral studies in the laboratory H. P. Lipp and D. P. Wolfer; 3. Ethogram R. T. Gerlai and W. E. Crusio; 4. Replicability and reliability of behavioral tests D. Wahlsten and J. C. Crabbe; Part II. Perception: 5. Audition J. F. Willott; 6. Behavioral measurement of mouse visual function G. T. Prusky and N. M. Alam; 7. Tactile system and nociception S. B. Smith and J. S. Mogil; 8. Olfactory acuity in Mus musculus H. Schellinck and B. Slotnick; 9. Taste genetics J. Boughter; Part III. Autonomous and Motor Behaviors: 10. Motor coordination in inbred mouse strains and the crucial role of the cerebellum R. Lalonde and C. Strazielle; 11. Reflex development F. Cirulli and E. Alleva; 12. Feeding and drinking R. J. Bodnar, S. R. Lewis and B. Kest; 13. Lateralization F. G. Biddle and B. A. Eales; 14. Rhythms and sleep: circadian and seasonal activity patterns B. Possidente; 15. Exploratory behavior W. E. Crusio; 16. Strains, SNPs and selected lines: genetic factors influencing variation in murine anxiety-like behavior A. Holmes; 17. Genetic influences on infant mouse ultrasonic vocalizations R. Benno and M. E. Hahn; 18. Startle behavior and prepulse inhibition C. F. Plappert and P. K. D. Pilz; 19. Mouse models of stress-induced depression-like behavior: stress vulnerability and antidepressant response as traits H. Gershenfeld; 20. Behavioral phenotyping of mouse grooming and barbering P. R. Canavello, J. M. Cachat, P. C. Hart, D. L. Murphy and A. V. Kalueff; Part IV. Social Behavior: 21. Social interaction C. Blanchard, J. Crawley, H. Arakawa and R. Blanchard; 22. Mouse sex: sexual differentiation and sexual behavior in Mus musculus L. Niel and D. A. Monks; 23. Nest-building behavior and the genetic correlation structure of adaptive phenotypes in house mice Abel Bult-Ito; 24. Aggression F. Sluyter, S. de Boer and S. C. Maxson; Part V. Learning and Memory: 25. Latent inhibition T. J. Gould and S. F. Logue; 26. Executive function: response inhibition, attention, and cognitive flexibility S. F. Logue and T. J. Gould; 27. Water navigation tasks D. P. Wolfer, G. Colacicco and H. Welzl; 28. Active and passive avoidance I. Branchi and L. Ricceri; 29. Radial maze W. E. Crusio and Herbert Schwegler; 30. Other mazes T. P. O'Leary and R. E. Brown; 31. Cued and contextual fear conditioning R. M. Gerlai; 32. Taste and odor H. Welzl and D. P. Wolfer; 33. Object recognition in the mouse E. Dere, A. Zlomuzica, M. A. De Souza Silva and J. P. Huston; Index.
£133.00
Cambridge University Press Experimental Design for Laboratory Biologists
Book SynopsisSpecifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.Trade Review'This is a wonderfully lucid introduction to experimental design, written by an author who is clearly aware of the pitfalls that exist for the unwary experimenter. The focus is on how to design experiments to ensure reproducible research, with many examples illustrating general principles that need to be understood to avoid error and bias. The coverage of statistical analysis follows on naturally from the design issues, and is amply illustrated with exercises in R. Highly recommended.' Dorothy Bishop, University of Oxford'Worldwide there is a salient discussion about deficiencies in the validity and predictiveness of research in the life sciences. Indeed, a fullblown 'reproducibility crisis' has been proclaimed. Against this backdrop this important textbook is a timely and highly useful contribution in the pressing quest to improve the robustness, rigor, and reproducibility of current biological and preclinical research. Proper experimental design is the bedrock for obtaining reliable evidence. By providing the necessary conceptual know-how and practical knowledge, [this book] enables investigators in all stages of their careers to minimize bias and improve statistical power through proper design and analysis of their experiments. This volume is unique … [as] it is immensely readable and accessible even for those with little previous knowledge, in combining all relevant aspects in a practical, concise and comprehensive manner, and in its clear focus on factors that help to improve the quality of research.' Ulrich Dirnagl, Charité University Hospital, Germany'There is an increasing need to better design experiments not only to reduce the number of any animals being used in any such work, but also to ensure that the data so produced is meaningful. As part of that process knowing how to power studies and then properly analyse the data so generated is vital, and of late there have been concerns that this is not been done to same vigour as that seen in the clinical arena. However, most scientists struggle with this aspect of their work, and thus it is really refreshing to come across a book that explicitly deals with experimental design and analysis. This new book clearly lays out what can and should be done and is written by an acknowledged expert and I have no doubt that this book will become a recommended read for all those contemplating undertaking work of this type.' Roger Barker, University of CambridgeTable of Contents1. Introduction: 1.1 What is reproducibility?; 1.2 The psychology of scientific discovery; 1.3 Are most published results wrong?; 1.4 Frequentist statistical interference; 1.5 Which statistics software to use?; 2. Key ideas in experimental design: 2.1 Learning versus confirming experiments; 2.2 The fundamental experimental design equation; 2.3 Randomisation; 2.4 Blocking; 2.5 Blinding; 2.6 Effect type: fixed versus random; 2.7 Factor arrangement: crossed versus nested; 2.8 Interactions between variables; 2.9 Sampling; 2.10 Use of controls; 2.11 Front-aligned versus end-aligned designs; 2.12 Heterogeneity and confounding; 3. Replication (what is 'N'?): 3.1 Biological units; 3.2 Experimental units; 3.3 Observational units; 3.4 Relationship between units; 3.5 How is the experimental unit defined in other disciplines?; 4. Analysis of common designs: 4.1 Preliminary concepts; 4.2 Background to the designs; 4.3 Completely randomised designs; 4.4 Randomised block designs; 4.5 Split-unit designs; 4.6 Repeated measures designs; 5. Planning for success: 5.1 Choosing a good outcome variable; 5.2 Power analysis and sample size calculations; 5.3 Optimal experimental designs (rules of thumb); 5.4 When to stop collecting data?; 5.5 Putting it all together; 5.6 How to get lucky; 5.7 The statistical analysis plan; 6. Exploratory data analysis: 6.1 Quality control checks; 6.2 Preprocessing; 6.3 Understanding the structure of the data; Appendix A. Introduction to R; Appendix B. Glossary.
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Nova Science Publishers Inc National Radiation Incidents: Laboratory Guide
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Nova Science Publishers Inc The Innate Immune System in Health and Disease:
Book SynopsisThe aim of this book is to provide updated information to scientists and clinicians that is valuable in their quest to gather information, carry out new investigations, and develop novel drugs that are more effective and do not cause adverse effects targeting the innate immune system. This book is of high priority to people interested in an update on innate immunity. Volume 1 examines the participation of innate immunity in diseases such as infections by viruses, cancer, or parasites. Specifically, this volume discusses innate immunity as it relates to chronic HIV infection, type 2 diabetes, and SARS-CoV-2, as well as its relationship with vitamin D. The dual role of neutrophils in cancer development and the plasticity of natural killer cells are investigated. Also, the immune response to infections from helminth and Toxoplasma gondii are described. The Innate Immune System in Health and Disease: From the Lab Bench Work to its Clinical Implications. Volume 1 promises to be a must-have book for all people who want to know about the role of the basic functioning of the innate immune system in several diseases of actual relevance to human health.
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Cambridge University Press Manual of Diagnostic Antibodies for Immunohistology
Book SynopsisThe rapid acceptance of immunohistochemistry as an important and even indispensable adjunct to morphological examination and diagnosis requires the modern anatomical pathology laboratory to be conversant with, and proficient in, immunostaining procedures, as well as methods of tissue processing and antigen retrieval and the underlying characteristics of the increasing number of antibodies and antisera available. This fully revised, expanded and updated edition provides a comprehensive list of antisera and monoclonal antibodies that have useful diagnostic applications in tissue sections and cell preparations. Various clones, which are commercially available to detect the same antigen, are listed and the sensitivities and specificities of the antibodies are discussed. Importantly, the authors, all pathologists with a wealth of experience in immunostaining procedures, provide fully referenced details and expert advice on each reagent, with the reader will find invaluable. Finally, the appendices provide easily accessible and clear summaries of selected antibody panels for specific diagnostic situations, details of heat-induced antigen/epitope retrieval (including the use of microwaves) and a useful reference to the websites of the main antibody suppliers.
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Bookwell Publications Safety in Health-cure Laboratories
Book SynopsisSuitable for health care laboratory workers and those responsible for laboratory administration and planning.
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Springer The Importance of Animal Experimentation for Safety and Biomedical Research
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Wiley Parasites of Lab Animals 2e
Book SynopsisPrepared under the auspices of the American College of Laboratory Animal Medicine, this second edition has been thoroughly updated and revised to improve utility and readability. The book is now organized by vertebrate host species, with parasites presented phylogenetically within chapters. Additional highlights of this edition include introductory chapters on modern diagnostic techniques and parasite biology, and a new appendix features a complete drug formulary. The well-presented and extensively illustrated volume addresses all aspects of laboratory animal parasites. Regarded as the most comprehensive and authoritative work available on the topic, this book is an essential reference for veterinary parasitologists, clinicians, students and laboratory animal scientists.Trade Review“Wait no more! After 35 years, the second edition of Flynn's Parasites of Laboratory Animals has finally arrived.... If you are looking for a well organized reference on parasites found in the research environment, then look no further. This is the most comprehensive, detailed, easy to use compilation available on the market. To collect the equivalent breadth, one would have to purchase many species-specific texts.... A detailed reference to be used to confirm preliminary results and enhance understanding of the impact of discovered infections. The articles are well written in an easy to read, direct, and succinct style... I recommend this text as a practical, user friendly yet extremely comprehensive reference book.” Interface: Newsletter of the Canadian Association for Laboratory Animal Medicine "The similarity of organization of each host chapter makes it easy to develop a method to use this large text. The tables at the end of each host chapter present information based on the host organ system and help direct the reader to more detailed references for each parasite. The text was carefully edited to maintain the same style throughout the book by different contributors.... Although this is not a book to use as a quick guide or a clinical differential, it is a good investment as a comprehensive reference text if: 1) you have an interest in parasitology, especially of laboratory animal species; 2) you are dealing with a commercial operation, such as a producer or distributor of any of these species; 3) you are a practitioner who sees these species on a fairly regular basis as pets." Exotic DVM Magazine “This is a well written and very useful book for those in the field of lab animal medicine. The second edition contains much newer useful information.” Doody’s Book Reviews "This is a well written and very useful book for those in the field of lab animal medicine. This second edition contains much newer useful information." (Allan John Paul, DVM, MS, @Doody's Review Service)Table of ContentsPreface to the Second Edition. List of Contributors. Acknowledgements. Dedication. Chapter 1- Collection, Preservation, and Diagnostic Methods. Chapter 2- Biology of the Protozoa. Chapter 3- Biology of Trematodes and Leeches. Chapter 4- Biology of Cestodes. Chapter 5- Biology of Nematodes and Acanthocephalans. Chapter 6- Biology of Arthropods. Chapter 7- Parasites of Fish. Chapter 8- Parasites of Amphibians. Chapter 9- Parasites of Reptiles. Chapter 10- Parasites of Birds. Chapter 11- Parasites of Rats and Mice. Chapter 12- Parasites of Hamsters. Chapter 13- Parasites of Gerbils. Chapter 14- Parasites of Guinea Pigs. Chapter 15- Parasites of Rabbits. Chapter 16- Parasites of Ferrets. Chapter 17- Parasites of Dogs. Chapter 18- Parasites of Cats. Chapter 19- Parasites of Swine. Chapter 20- Parasites of Sheep and Goats. Chapter 21- Parasites of Non-human Primates. Appendix- Formulary. Glossary
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Legare Street Press Klinische Chemie
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Legare Street Press Die Blut Morphologie der LaboratoriumsTiere
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Legare Street Press On the Question of the Occurrence of Creatinine and Creatine in Blood
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Legare Street Press Laboratory Methods of Histology and Bacteriology
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Legare Street Press The The Newer Methods of Blood and Urine Chemistry
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Legare Street Press Praktikum Der Klinischen Chemischen Mikroskopischen Und Bakteriologischen Untersuchungsmethoden
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Creative Media Partners, LLC Pathological Technique
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Creative Media Partners, LLC Practical Uranalysis and Urinary Diagnosis
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Creative Media Partners, LLC Pathological Technique
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Creative Media Partners, LLC Pathological Technique
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Hutson Street Press Manuel De Microscopie Clinique Microscopie LÃcgale Chimie Clinique Technique BactÃcrioscopique
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Hutson Street Press Manuel De Microscopie Clinique Microscopie LÃcgale Chimie Clinique Technique BactÃcrioscopique
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Creative Media Partners, LLC Microscopy and Bacteriology a Manual for Students and Practitioners
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Creative Media Partners, LLC Microscopy and Bacteriology a Manual for Students and Practitioners
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