Epidemiology and Medical statistics Books

Book SynopsisOne doctor’s surprising answer to the epidemic of chronic disease and essential reading for everyone concerned with the health of the next generation ..[T]he further we move away from nature the sicker we become, and it is our children who pay the heaviest price for what modern civilization is doing to our environment and our bodies. This book will make the reader think. I warmly recommend it! Dr. Natasha Campbell-McBride, MD, author of Gut and Psychology Syndrome Over the past fifty years, rates of autoimmunity and chronic disease have exploded. While some attribute this rise to increased awareness and diagnosis, Thomas Cowan, MD, argues for a direct causal relationship to a corresponding increase in the number of vaccines children typically receive. Dr. Cowan looks at emerging evidence that certain childhood illnesses are actually protective of disease later in life; examines the role of fever, the gut and cellular fluid in immune health; argues that vaccination is an ineffective (and harmful) attempt to shortcut a complex immune response; and asserts that the medical establishment has engaged in an authoritarian argument that robs parents of informed consent. His ultimate question, from the point of view of a doctor who has decades of experience treating countless children is: What are we really doing to children when we vaccinate them? Dr. Cowan intelligently educates us on the complicated and beautiful workings of our immune system, clearly explains how and why its malfunction is harming us, and elucidates why our precious children are so vulnerable to these diseases. Lindy Woodard, MD, Pediatric AlternativesTrade Review“Dr. Tom Cowan has created an entertaining, compelling, and readily accessible book explaining the risks involved in today’s overaggressive vaccination campaign. I particularly appreciate his emphasis on the risks to autoimmune disease inherent in antibody induction through vaccines. This book is a great addition to the growing body of literature revealing why vaccination is not the best strategy for protection against infectious diseases.”—Stephanie Seneff, senior research scientist, MIT Computer Science and Artificial Intelligence Laboratory“I would like to thank Dr. Tom Cowan for writing this book! Humanity seems to have forgotten that human body is part of nature; the further we move away from nature the sicker we become, and it is our children who pay the heaviest price for what modern civilization is doing to our environment and our bodies. This book will make the reader think. I warmly recommend it!”—Dr. Natasha Campbell-McBride, MD, author of Gut and Psychology Syndrome“Dr. Cowan does a great job explaining in clear and common-sense terms that the practice and the rationale of vaccination is deeply flawed, and, astoundingly, is not evidence-based but rather fear-based. The vaccine paradigm is upheld by the consensus, but the consensus in not based on a free and unbiased reading of all the evidence, rather only on a small part of it, while much is ignored. Dr. Cowan contributes greatly to a much-needed correction of this misleading and misled consensus.”—Philip Incao, MD, advisor, Physicians for Informed Consent“Tom Cowan’s Vaccines, Autoimmunity, and the Changing Nature of Childhood Illness is both brilliant and beautifully simple. He shares facts not taught in medical school, that reflect ancient wisdom, common sense, and trust in the intelligence of life itself. Understanding the role of childhood illnesses such as chickenpox and measles is critical to our survival as a species. Tom does an outstanding job of connecting the dots and giving reason to what is often misunderstood!”—Cilla Whatcott, producer of the film Real Immunity; author of There is a Choice“As a pediatrician for thirty-five years, I have seen the enormous rise in autoimmune diseases like asthma, allergies, eczema, and autism. We no longer need to scratch our heads wondering why, because the reasons are clear. In Vaccines, Autoimmunity, and the Changing Nature of Childhood Illness, Dr. Cowan intelligently educates us on the complicated and beautiful workings of our immune system, clearly explains how and why its malfunction is harming us, and elucidates why our precious children are so vulnerable to these diseases. Most importantly, perhaps, Dr. Cowan charts the clear, concise path to healing, offering a better, healthier life for us, our children, and the planet.”—Lindy Woodard, MD, Pediatric Alternatives“We westerners must wake up to the fact that vaccination is driving our modern epidemics of autism, dementia, autoimmunity, and allergies. In Vaccines, Autoimmunity, and the Changing Nature of Childhood Illness, Dr. Thomas Cowan whistle-blows on Big Pharma and the medical profession. Quite rightly, too. Human misery aside, these diseases are debilitatingly expensive. Autism usually results in care for life. “The arguments Dr. Cowan makes are not only biologically plausible, but are based in good science. He states what, for many, is the obvious: we must learn to live within the laws of nature, not fight against them as if they were some evil force. Evolution has the answers! We have lived with microorganisms for millions of years, and many confer significant survival benefits. Cowan details this with devastating logic. Childhood infections such as chickenpox and measles are desirable; they program the immune system in such a way as to protect us from disease later in life. “This book gives parents the intellectual ammunition they need to fight back against the pro-vaccine medical establishment. They clearly need such. I have seen parents driven by fear into vaccinating their children entirely against their parental instincts. By not vaccinating, Cowan shows us how children can be protected from allergy, autoimmunity, attention deficit/hyperactivity disorder, asthma, and autism. This book is essential reading for all concerned with the health of the next generation.”—Dr. Sarah Myhill, author of Sustainable Medicine and Diagnosis and Treatment of Chronic Fatigue Syndrome and Myalgic Encephalitis“Thomas Cowan, MD, is a gifted physician and scientist. He is also a man of integrity who sticks his neck out for the truth. In addition he has the talent for making complex and urgent topics easy to read and understand for the intelligent layperson. He has accomplished this with his book, Human Heart, Cosmic Heart, the best book out there on holistically healing cardiovascular diseases. Now he has done it again with Vaccines, Autoimmunity, and the Changing Nature of Childhood Illness. “Vaccination has been a controversial topic for decades with informed parents around the world having to struggle with regulatory authorities and doctors over the necessity and effectiveness of vaccination to prevent childhood diseases. Now Dr. Cowan comes out with a powerful book giving a clear scientific voice to the intuition of many parents regarding the dangers of vaccination. Tamper with our immune system through one-sided interventions, and pay a tragic price. “This book is a global wake-up call to defend, against those who would destroy it, the awesome wisdom of the human body to wage its own battle against the myriad diseases that seek to overcome our internal defense system. This book will have a profound, beneficial impact on human health around the world in the years and decades to come. It is a courageous and pioneering work worthy of admiration and support.”—Nicanor Perlas, recipient, Right Livelihood Award

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Book SynopsisComputing power has revolutionized the theory and practice of statistical inference. This book delivers a concentrated course in modern statistical thinking by tracking the revolution from classical theories to the large-scale prediction algorithms of today. Anyone who applies statistical methods to data will benefit from this landmark text.Trade Review'How and why is computational statistics taking over the world? In this serious work of synthesis that is also fun to read, Efron and Hastie, two pioneers in the integration of parametric and nonparametric statistical ideas, give their take on the unreasonable effectiveness of statistics and machine learning in the context of a series of clear, historically informed examples.' Andrew Gelman, Columbia University, New York'This unusual book describes the nature of statistics by displaying multiple examples of the way the field has evolved over the past sixty years, as it has adapted to the rapid increase in available computing power. The authors' perspective is summarized nicely when they say, 'very roughly speaking, algorithms are what statisticians do, while inference says why they do them'. The book explains this 'why'; that is, it explains the purpose and progress of statistical research through a close look at many major methods, methods the authors themselves have advanced and studied at great length. Both enjoyable and enlightening, Computer Age Statistical Inference is written especially for those who want to hear the big ideas, and see them instantiated through the essential mathematics that defines statistical analysis. It makes a great supplement to the traditional curricula for beginning graduate students.' Rob Kass, Carnegie Mellon University, Pennsylvania'This is a terrific book. It gives a clear, accessible, and entertaining account of the interplay between theory and methodological development that has driven statistics in the computer age. The authors succeed brilliantly in locating contemporary algorithmic methodologies for analysis of 'big data' within the framework of established statistical theory.' Alastair Young, Imperial College London'This is a guided tour of modern statistics that emphasizes the conceptual and computational advances of the last century. Authored by two masters of the field, it offers just the right mix of mathematical analysis and insightful commentary.' Hal Varian, Google'Efron and Hastie guide us through the maze of breakthrough statistical methodologies following the computing evolution: why they were developed, their properties, and how they are used. Highlighting their origins, the book helps us understand each method's roles in inference and/or prediction. The inference-prediction distinction maintained throughout the book is a welcome and important novelty in the landscape of statistics books.' Galit Shmueli, National Tsing Hua University'A masterful guide to how the inferential bases of classical statistics can provide a principled disciplinary frame for the data science of the twenty-first century.' Stephen Stigler, University of Chicago, and author of Seven Pillars of Statistical Wisdom'Computer Age Statistical Inference offers a refreshing view of modern statistics. Algorithmics are put on equal footing with intuition, properties, and the abstract arguments behind them. The methods covered are indispensable to practicing statistical analysts in today's big data and big computing landscape.' Robert Gramacy, University of Chicago Booth School of Business'Every aspiring data scientist should carefully study this book, use it as a reference, and carry it with them everywhere. The presentation through the two-and-a-half-century history of statistical inference provides insight into the development of the discipline, putting data science in its historical place.' Mark Girolami, Imperial College London'Efron and Hastie are two immensely talented and accomplished scholars who have managed to brilliantly weave the fiber of 250 years of statistical inference into the more recent historical mechanization of computing. This book provides the reader with a mid-level overview of the last 60-some years by detailing the nuances of a statistical community that, historically, has been self-segregated into camps of Bayes, frequentist, and Fisher yet in more recent years has been unified by advances in computing. What is left to be explored is the emergence of, and role that, big data theory will have in bridging the gap between data science and statistical methodology. Whatever the outcome, the authors provide a vision of high-speed computing having tremendous potential to enable the contributions of statistical inference toward methodologies that address both global and societal issues.' Rebecca Doerge, Carnegie Mellon University, Pennsylvania'In this book, two masters of modern statistics give an insightful tour of the intertwined worlds of statistics and computation. Through a series of important topics, Efron and Hastie illuminate how modern methods for predicting and understanding data are rooted in both statistical and computational thinking. They show how the rise of computational power has transformed traditional methods and questions, and how it has pointed us to new ways of thinking about statistics.' David Blei, Columbia University, New York'Absolutely brilliant. This beautifully written compendium reviews many big statistical ideas, including the authors' own. A must for anyone engaged creatively in statistics and the data sciences, for repeated use. Efron and Hastie demonstrate the ever-growing power of statistical reasoning, past, present, and future.' Carl Morris, Harvard University, Massachusetts'Computer Age Statistical Inference gives a lucid guide to modern statistical inference for estimation, hypothesis testing, and prediction. The book seamlessly integrates statistical thinking with computational thinking, while covering a broad range of powerful algorithms for learning from data. It is extraordinarily rare and valuable to have such a unified treatment of classical (and classic) statistical ideas and recent 'big data' and machine learning ideas. Accessible real-world examples and insightful remarks can be found throughout the book.' Joseph K. Blitzstein, Harvard University, Massachusetts'Among other things, it is an attempt to characterize the current state of statistics by identifying important tools in the context of their historical development. It also offers an enlightening series of illustrations of the interplay between computation and inference … This is an attractive book that invites browsing by anyone interested in statistics and its future directions.' Bill Satzer, Mathematical Association of America Reviews'My take on Computer Age Statistical Inference is that experienced statisticians will find it helpful to have such a compact summary of twentieth-century statistics, even if they occasionally disagree with the book's emphasis; students beginning the study of statistics will value the book as a guide to statistical inference that may offset the dangerously mind-numbing experience offered by most introductory statistics textbooks; and the rest of us non-experts interested in the details will enjoy hundreds of hours of pleasurable reading.' Joseph Rickert, RStudio (www.rstudio.com)'Efron and Hastie (both, Stanford Univ.) have superbly crafted a central text/reference book that presents a broad overview of modern statistics. The work examines major developments in computation from the late-20th and early-21st centuries, ranging from electronic computations to 'big data' analysis. Focusing primarily on the last six decades, the text thoroughly documents the progression within the discipline of statistics … This text is highly recommended for graduate libraries.' D. J. Gougeon, ChoiceTable of ContentsPart I. Classic Statistical Inference: 1. Algorithms and inference; 2. Frequentist inference; 3. Bayesian inference; 4. Fisherian inference and maximum likelihood estimation; 5. Parametric models and exponential families; Part II. Early Computer-Age Methods: 6. Empirical Bayes; 7. James–Stein estimation and ridge regression; 8. Generalized linear models and regression trees; 9. Survival analysis and the EM algorithm; 10. The jackknife and the bootstrap; 11. Bootstrap confidence intervals; 12. Cross-validation and Cp estimates of prediction error; 13. Objective Bayes inference and Markov chain Monte Carlo; 14. Statistical inference and methodology in the postwar era; Part III. Twenty-First Century Topics: 15. Large-scale hypothesis testing and false discovery rates; 16. Sparse modeling and the lasso; 17. Random forests and boosting; 18. Neural networks and deep learning; 19. Support-vector machines and kernel methods; 20. Inference after model selection; 21. Empirical Bayes estimation strategies; Epilogue; References; Index.

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Book SynopsisThis is the quick, go-to-reference book for public health trainees and practitioners. It distils information from the core disciplines of public health into one concise volume. It is also packed with practical tips on professional competencies and skills development, as well as new emerging topics.Trade ReviewReview from previous edition All occupational physicians including trainees and those looking to conduct research, practising physicians who interpret workforce data and plan interventions and senior colleagues working at the strategic level will find something of relevance in this book. There is an immense amount of content for such a small book and, as such, it represents good value for money. * Lachlan Mackay Brown, Occupational Medicine, 64 (2014) *This fantastic little handbook has had a group of excellent editors over the previous two editions and this third edition sees four well-known and rather different public health advocates and practitioners take over the reins...For whom would I recommend this book? Just about everybody! All practitioners and students of public health without question. * Australian and New Zealand Journal of Public Health *For whom would I recommend this book? Just about everybody! All practitioners and students of public health without question ... My old copies of this book are scruffy and dog-eared and much loved. I can tell that in time this edition will be, too. * Australian and New Zealand Journal of Public Health *This is a useful core text for trainees in that it gives a succinct view on the key public health topics, issues and skills. It is also useful for established specialists... This fills an almost unique gap in the market as a quick guide and handbook to real-life public health practice. * BMA Book Awards 2014. Winner in Public Health category *Table of Contents1. Assessment 1.1: Gabriele Bammer: Scoping public health problems 1.2: Sian M. Griffiths, Robyn Martin, and Don Sinclair: Priorities and ethics in health care 1.3: Julian Flowers: Assessing health status 1.4: John Wright and Ben Cave: Assessing health needs 1.5: Alex Scott-Samuel, Kate Ardern, and Martin Birley: Assessing health impacts 1.6: Peter Brambleby: Economic assessment 2. Data and information 2.1: Barry Tennison and Lamberto Manzoli: Understanding data, information, and knowledge 2.2: Don Detmer: Information technology and informatics 2.3: Sara Mallinson, Jennie Popay, and Gareth Williams: Questions, design, and analysis in qualitative research 2.4: Walter Ricciardi and Stefania Boccia: Epidemiological approach and design 2.5: Kalyanaraman Kumaran and Iain Lang: Statistical understanding 2.6: Iain Lang: Inference, causality, and interpretation 2.7: Anne Brice, Amanda Burls, and Alison Hill: Finding and appraising evidence 2.8: Richard Hopkins and Aaron Kite-Powell: Monitoring disease and risk factors: surveillance 2.9: Patrick Saunders, Andrew Kibble, Amanda Burls, and A.T Saunders: Investigating alleged clusters 2.10: Rachael Brok, Sara Stevens, and Jem Rashbass: Assessing longer-term health trends: disease registers 3. Direct action 3.1: Sarah O>'Brien: Communicable disease epidemics 3.2: Wendy Heiger-Bernays and Kathryn Crawford: Environmental health risks & assessment 3.3: Stefanos N. Kales and Michael S. Chin: Safeguarding and promoting health in the workplace 3.4: Meredith Minkler and Charlotte Chang: Engaging communities in participatory research and action 3.5: Paul Bolton and Frederick M. Burkle, Jr: Disasters 3.6: Angela Raffle, Alex Barratt, and J. A. Muir Gray: Assuring screening programmes 3.7: Hilary Burton and Mark Kroese: Genomics 3.8: Rachel Faulkenberry, Mesfin Bekalu, and Kasisomayajula Viswanath: Health communication 3.9: Steve Gillam: Public health practice in primary care 3.10: Shoba Ramanadhan: Translating research into practice DS implementation science 4. Policy arenas 4.1: Don Nutbeam: Developing healthy public policy 4.2: Lauren Smith and Ichiro Kawachi: Translating evidence to policy 4.3: John Battersby: Translating policy into indicators and targets 4.4: Rebekah A. Jenkin, Christine M. Jorm, and Michael S. Frommer: Translating goals, indicators, and targets into public health action 4.5: Simon Chapman and Becky Freeman: Media advocacy for policy influence 4.6: Tim Lang and Martin Caraher: Influencing international policy 4.7: Nicholas Banatvala and Eric Heymann: Public health in poorer countries 4.8: Lawrence Gostin: Regulation 4.9: David Pencheon, Sonia Roschnik, and Paul Cosford: Health, sustainability, and climate change 5. Healthcare systems 5.1: Elena Azzolini, Mary Harney, and Walter Ricciardi: Sustainability of healthcare systems 5.2: David Lawrence: Planning health services 5.3: Martin McKee and Ellen Nolte: Comparing healthcare systems 5.4: Richard Richards: Commissioning healthcare 5.5: Thomas Rice: Controlling expenditures 5.6: Corrado De Vito and Paolo Villari: Using guidance and frameworks 5.7: Diana Delnoij: Health care process and patient experience 5.8: Chiara de Waure and Carlo Favaretti: Health technology assessment 5.9: Sharon Friel: Improving equity 5.10: Nick Steel, John Ford, and Iain Lang: Improving quality 5.11: Martin McKee, Marina Karanikolos, and Ellen Nolte: Evaluating health care systems 5.12: Muir Gray and Walter Ricciardi: Value-based healthcare 6. Personal effectiveness 6.1: Fiona Sim: Developing leadership skills 6.2: Edmund Jessop: Effective meetings 6.3: Edmund Jessop: Effective writing 6.4: Alan Maryon-Davis: Working with the media 6.5: John Ford, Nick Steel, and Charles Guest: Communicating risk 6.6: Charles Guest: Consultancy in a national strategy 6.7: Leonard Marcus: Effective negotiation 7. Organizations 7.1: Virginia Pearson: Governance and accountability 7.2: John Fien: Programme planning and project management 7.3: Mike Gogarty: Business planning 7.4: Shannon L. Sibbald, Anita Kothari, Malcolm Steinberg, and Beverley Bryant: Working in teams in public health 7.5: Julian Elston: Partnerships 7.6: Jeanette Ward and Jeremy Grimshaw: Getting research into practice 7.7: Felix Greaves and Charles Guest: Workforce

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Book SynopsisAccessible, practical, and student-friendly, Systematic Reviews to Answer Health Care Questions, Second Edition, by Dr. Heidi D. Nelson, uses easy-to-understand, step-by-step instruction and real-world examples to illustrate important concepts and principles of today’s systematic reviews. You’ll learn how to form key questions, select evidence, and perform comprehensive reviews not just in predictable circumstances, but when basic rules don’t apply—honing your ability to think critically and solve problems. Perfect for investigators, medical students and faculty, practitioners, policymakers, and others who need to refine their understanding of or approach to systematic reviews, this powerful text goes beyond merely teaching how to catalog and collect, helping readers learn to evaluate, synthesize, and deliver results that will help shape the practice of health care. Provides concise, easy-to-follow instruction on how to conduct a high-quality systematic review that meets current standards in the field—from key question formulation to assessing the quality of included studies and reporting results Features updated methods and revised case studies throughout, along with new chapters on assessing quality and applicability of additional study designs and electronic tools designed to automate or improve efficiency of systematic reviews Covers the essential, practical components of how to perform a systematic review, such as defining a review’s purpose and scope, developing research questions, building a team, and managing the project to maximize efficacy Offers a useful framework to help understand how evidence is evaluated, what it means, its weaknesses or assumptions, and more Shares the knowledge and expertise of Dr. Heidi D. Nelson, a leader in the field of systematic reviews for more than 25 years, whose work has been used in shaping healthcare guidelines and policy in the United States, along with a select group of expert contributing authors An ideal resource for investigators conducting their own systematic reviews; guideline and policy committees tasked with interpreting and applying systematic reviews; students learning the science of research design, critical appraisal, and grading strength of evidence; and practitioners or others outside of health care who need a better understanding of evidence

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Book SynopsisIntroduction to Pharmaceutical Calculations is an essential study aid for pharmacy students. The book contains worked examples and sample questions and answers.Table of Contents1 Introduction; 2 Rational Numbers; 3 Systems of Units; 4 Concentrations; 5 Dilutions; 6 Formulations; 7 Calculation of Doses; 8 Doses in Children; 9 Density, Displacement Volumes and Displacement Values; 10 Calculations Involving Molecular Weights; 11 Parenteral Solutions and Isotonicity; 12 Accuracy of Measurement; 13 Calculations Involving Information Retrieval.

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Book Synopsis"An invaluable portrait of the evolution of international health in recent decades." —William Bynum, Wall Street JournalTrade Review"An invaluable portrait of the evolution of international health in recent decades…We need more people like Peter Piot who will rise to the occasion with spirit and passion." -- William Bynum - Wall Street Journal"[A] fascinating account of the complex behavioural responses that epidemics trigger among their human hosts." -- José Esparza - Nature"From laboratories to field epidemiology, boardrooms and political chambers, [No Time To Lose] charts an incredibly impactful career in science and the fine arts of diplomacy, communication and political engagement in difficult situations." -- Chikwe Ihekweazu - Nature"Insightful." -- Andrew Jack - Financial Times"A riveting read." -- Laurie Garrett - The Lancet"A timely and accessible memoir…enthralling reading…will appeal to budding young scientists." -- Booklist (starred review)"Piot helped assure that affordable drugs revolutionizing AIDS treatment would be available to the poorest victims. He leaves a legacy of change and hope in two worlds—medicine and politics—and an urgent reminder that their cooperation saves lives." -- Publishers Weekly (starred review)

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Book SynopsisThe ultimate guide to dissemination and implementation research for public health, medicine, and the social sciencesIn the past twenty years, dissemination and implementation (D&I) research has sought to narrow the gap between the discovery of new knowledge and its application in public health, mental health, and health care settings. The challenges of moving research to practice and policy are universal, and future progress calls for collaborative partnerships and cross-country research. The fundamental tenet of D&I research-taking what we know about improving health and putting it into practice-must be the highest priority. Dissemination and Implementation Research in Health is the definitive roadmap to effecting change in health and science from today''s leading D&I researchers. With insights from around the globe, these scholars collectively address key issues in the field including how to evaluate evidence based on effective interventions, how to design an appropriate study, and hTrade ReviewThe third edition of Dissemination and Implementation Research in Health is comprehensive, relevant, insightful, and practical. It addresses one of the greatest challenges across health and many other fields—the persistent gap between evidence and its implementation to benefit people and the planet. This new edition builds upon the outstanding foundation of earlier editions, with an even stronger focus on equity and global settings. It is a must-read book. * Barbara K. Rimer, DrPH, Alumni Distinguished Professor and Dean Emerita, Gillings School of Global Public Health, University of North Carolina at Chapel Hill *This third edition arrives at the right time for scholars and all others committed to implementing effective strategies into health practice and policy. The coronavirus pandemic has challenged us to rethink our assumptions about how quickly care can change, while also revealing the scope and impact of longstanding inequities in health care. With some of the top global scholars in dissemination and implementation research, this book guides readers through each component of robust implementation research practices for modern day care. It should be required reading for all those who seek to achieve a learning healthcare system and evidence informed health policy. * Lisa Simpson, MB, BCh, MPH, FAAP, President and Chief Executive Officer, AcademyHealth *

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Book SynopsisThe 2014 Ebola epidemic demonstrated the power of pandemics and their ability not only to destroy lives locally but also to capture the imagination and terrify the world. Christian W. McMillen provides a concise yet comprehensive account of pandemics throughout human history, illustrating how pandemic disease has shaped history and, at the same time, social behavior has influenced pandemic disease. Extremely interesting from a medical standpoint, the study of pandemics also provides unexpected, broader insights into culture and politics.This Very Short Introduction describes history''s major pandemics - plague, tuberculosis, malaria, smallpox, cholera, influenza, and HIV/AIDS - highlighting how each disease''s biological characteristics affected its pandemic development. McMillen discusses state responses to pandemics, such as quarantine, isolation, travel restrictions, and other forms of social control, and pays special attention to the rise of public health and the explosion of medical research in the wake of pandemics, especially as the germ theory of disease emerged in the late nineteenth and early twentieth centuries. Today, medicine is able to control all of these diseases, yet some of them are still devastating in much of the developing world. By assessing the relationship between poverty and disease and the geography of epidemics, McMillen offers an outspoken and thought-provoking point of view on the necessity for global governments to learn from past experiences and proactively cooperate to prevent any future epidemic.Table of ContentsIntroduction Chapter 1: Plague Chapter 2: Smallpox Chapter 3: Malaria Chapter 4: Cholera Chapter 5: Tuberculosis Chapter 6: Influenza Chapter 7: HIV/AIDS References Further Reading Index

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Book SynopsisFrom the bestselling author of Everything Bad is Good For You, Steven Johnson''s The Ghost Map vividly recreates Victorian London to show how huge populations live together, how cities can kill - and how they can save us. Steven Johnson is one of today''s most exciting writers about popular culture, urban living and new technology. In The Ghost Map he tells the story of the terrifying cholera epidemic that engulfed London in 1854, and the two unlikely heroes - anesthetist Doctor John Snow and affable clergyman Reverend Henry Whitehead - who defeated the disease through a combination of local knowledge, scientific research and map-making. In telling their extraordinary story, Steven Johnson also explores a whole world of ideas and connections, from urban terror to microbes, ecosystems to the Great Stink, cultural phenomena to street life. ''A wonderful book''  Mail on Sunday ''A thumping page-turne

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Book SynopsisDesigned to support the best-selling third edition of Medical Statistics at a Glance, this comprehensive workbook contains a variety of self-assessment methods allowing readers to test their statistical knowledge, put it into practice, and apply it to a medical context and when reading published literature.Trade ReviewGreat workbook that compliments the respective textbook. Excercises are practical, short to the point. Good book of helping to understand the underlying concepts. (Anthony Murray, Faculty of Health & Science, University of Cumbria)Table of ContentsIntroduction 6 Part 1: Multiple-choice questions 8 Handling data 8 Sampling and estimation 10 Study design 11 Hypothesis testing 13 Basic techniques for analysing data 13 Additional techniques 20 Part 2: Structured questions 24 Part 3: Critical appraisal 44 Randomised controlled trial: template 44 Randomised controlled trial: Paper 1 46 Observational study: template 51 Observational study: Paper 2 53 Part 4: Data analysis 61 Dataset 1 analysed by Stata v11 (StataCorp LP, Texas, USA) 61 Dataset 2 analysed using IBM SPSS Statistics v20 70 Part 5: Solutions 76 Solutions to multiple-choice questions 76 Model answers for structured questions 93 Randomised controlled trial: critical appraisal of Paper 1 109 Observational study: critical appraisal of Paper 2 113 Appendices 117 Appendix I: list of multiple-choice questions with relevant chapter numbers from Medical Statistics at a Glance (3rd edn) and associated topics 117 Appendix II: list of structured questions with relevant chapter numbers from Medical Statistics at a Glance (3rd edn) and associated topics 119 Appendix III: chapter numbers from Medical Statistics at a Glance (3rd edn) with relevant multiple-choice questions and structured questions 120

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Book SynopsisThis book provides an up-to-date, comprehensive, clinically oriented account of the molecular biology, pathogenesis, clinical features, diagnosis and management of human bacterial diseases, as well as their control and prevention.Trade Review"...this book is written well..." (Statistics in Medical Research, Vol.12, No. 2, 2003)Table of ContentsThe Scope of Survival Analysis. Randomized Clinical Trials: General Principles and Some Controversial Issues. Estimation of Survival Probabilities. Non-Parametric Methods for the Comparison of Survival Curves. Distribution Functions for Failure Time T . The Cox Regression Model. Validation of the Proportional Hazards Models. Parametric Regression Models. The Study of Prognostic Factors and the Assessment of Treatment Effect. Competing Risks. Meta-Analysis. References. Indexes.

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Book SynopsisFay and Brittain present statistical hypothesis testing and compatible confidence intervals, focusing on application and proper interpretation. The emphasis is on equipping applied statisticians with enough tools - and advice on choosing among them - to find reasonable methods for almost any problem and enough theory to tackle new problems by modifying existing methods. After covering the basic mathematical theory and scientific principles, tests and confidence intervals are developed for specific types of data. Essential methods for applications are covered, such as general procedures for creating tests (e.g., likelihood ratio, bootstrap, permutation, testing from models), adjustments for multiple testing, clustering, stratification, causality, censoring, missing data, group sequential tests, and non-inferiority tests. New methods developed by the authors are included throughout, such as melded confidence intervals for comparing two samples and confidence intervals associated with WilTrade Review'A necessary book for the applied statistician seeking to understand the theoretical underpinnings of statistical methods and for graduate students knowledgeable about statistical theory but lacking experience in application. The book is chock full of challenging examples that point to the complexities of choice of method. A particularly valuable feature of the book is the authors' description of competing methods coupled with their clarity in explaining and justifying why they prefer one method over others. Fay and Brittain should sit on every statistician's bookshelf.' Janet Wittes, WCG Statistics Collaborative'Good statistical hypothesis testing and confidence interval construction involves mathematical aspects of finding a good test given a probability model and scientific aspects of determining the appropriateness of a probability model for answering a scientific question. This book provides a lucid discussion of both these mathematical and scientific aspects with compelling scientific examples. I most highly recommend this book.' Dylan Small, University of Pennsylvania'Congratulations to Fay and Brittain for this wonderful reference book that does what its somewhat unusual title suggests: puts hypothesis testing in the context of science. The vast coverage of topics, extensive bibliography and notes, and easy to understand explanations make 'Statistical Hypothesis Testing in Context: Reproducibility, Inference, and Science' an indispensable tool in the arsenal of any applied or theoretical statistician or biostatistician. I enthusiastically recommend buying the book!' Michael A. Proschan, National Institute of Allergy and Infectious DiseasesTable of Contents1. Introduction; 2. Theory of tests, p-values, and confidence intervals; 3. From scientific theory to statistical hypothesis test; 4. One sample studies with binary responses; 5. One sample studies with ordinal or numeric responses; 6. Paired data; 7. Two sample studies with binary responses; 8. Assumptions and hypothesis tests; 9. Two sample studies with ordinal or numeric responses; 10. General methods for creating decision rules; 11. K-Sample studies and trend tests; 12. Clustering and stratification; 13. Multiplicity in testing; 14. Testing from models; 15. Causality; 16. Censoring; 17. Missing data; 18. Group sequential and related adaptive methods; 19. Testing fit, equivalence, and non-inferiority; 20. Power and sample size.

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Book SynopsisIn 2014, a 28-year old British doctor found himself co-running the Ebola isolation unit in Sierra Leone’s main hospital after the doctor in charge had been killed by the virus. Completely overwhelmed and wrapped in stifling protective suits, he and his team took it in turns to provide care to patients while removing dead bodies from the ward. Against all odds he battled to keep the hospital open, as the queue of sick and dying patients grew every day. Only a few miles down the road the Irish Ambassador and Head of Irish Aid worked relentlessly to rapidly scale up the international response. At a time when entire districts had been quarantined, she travelled around the country, and met with UN agencies, the President and senior ministers so as to be better placed in alerting the world to the catastrophe unfolding in front of her. In this blow-by-blow account, Walsh and Johnson expose the often shocking shortcomings of the humanitarian response to the outbreak, both locally and internationally, and call our attention to the immense courage of those who put their lives on the line every day to contain the disease. Theirs is the definitive account of the fight against an epidemic that shook the world.Trade ReviewGetting to Zero is a compelling read, full of compassion, grief, ingenuity and stories of courage and unstinting commitment of local nurses, cleaners and others who remain unsung heroes of Ebola. But it is also full of tales of denial, extraordinary lapses in leadership and awkward truths that will make uncomfortable reading for many, locally and internationally. * Guardian *Written in an honest and engaging tone, their experience behind the scenes of the outbreak is illuminating and highlights important lessons for the management of future outbreaks, and the operational errors that increased the number of lives lost in the west African outbreak of 2014–16. * Lancet *Hundreds of reports have been written on the 2014 epidemic – the most widespread Ebola outbreak since the virus was discovered – but none is nearly as insightful, compassionate or unsparing as this. * Irish Times *A brave, bold, yet humble account from the frontlines of the Ebola outbreak in Sierra Leone. This is vital reading to help us all do better next time. * David Miliband, President and CEO of the International Rescue Committee *Courage in extreme clinical danger, courage to challenge obstructive bureaucracy, courage to make tough decisions and the courage to endure. This is the courage that Sinead Walsh and Oliver Johnson displayed in Sierra Leone. Their compelling book is essential reading for all who care about global health. * Eldryd Parry, founder of the Tropical Health and Education Trust *A captivating and brutally honest account of the Ebola epidemic from two brave, committed individuals who unexpectedly found themselves at its epicentre. The authors pull no punches, and leave us asking: will these lessons be learned, or will the world once again forget and move on? * Jeremy Farrar, Director of the Wellcome Trust *This powerful book asks important questions about aid and development and offers insights that everyone working in global health should absorb – as well as being a personal and very moving account of an epidemic that killed thousands. * Lord Nigel Crisp, Co-Chair of the All Party Parliamentary Group on Global Health *Walsh and Johnson represent the best of international intervention. This book reveals the complexities and level of cooperation that made “getting to zero” possible. Offers excellent insight into those trying times. * O.B. Sisay, Director of the Situation Room at the National Ebola Response Centre, Sierra Leone *An extraordinary account from the thick of the battle against Ebola. This is history’s first draft, and a powerful example of persistent and pragmatic leadership. Mandatory reading for anyone concerned with global health in the broadest sense. * Paul Farmer, Harvard Medical School, and co-founder of Partners in Health *Takes us behind the scenes to the harrowing frontlines of the Ebola epidemic – highlighting a set of lessons that an inter-connected world would ignore at our peril. A compelling read. * Samantha Power, former US Ambassador to the UN *A detailed, up-close-and-personal perspective on the Ebola epidemic in Sierra Leone, important for all who want to understand what it is to confront a terrible health threat. * Tom Frieden, President and CEO of Resolve to Save Lives, and former Director of the Centers for Disease Control and Prevention *Johnson and Walsh provide a frank, beautifully written, and essential guide to the lessons learned from the heart of the outbreak. Their first-hand experiences in battling this terrible disease will take your breath away. A must read. * Tulip Mazumdar, Global Health Correspondent for BBC News *Table of ContentsMaps Preface 1. New Beginnings: Sierra Leone before the Outbreak of Ebola 2. A Dubious Start: Ebola in Guinea 3. Ebola Emerges in Sierra Leone 4. Kenema Explodes 5. Armageddon 6. The Long Wait for Action 7. The Response Kicks Off 8. The Response Bears Fruit 9. Getting to Zero 10. Conclusion Afterword: If We Had to Do It All Again…

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Book SynopsisA time-tested, landmark approach to health promotion and communication projects and everything that goes into making them successful. For more than 40 years, the PRECEDE-PROCEED model, developed in the early 1970s by Lawrence W. Green and first published as a text in 1980 with Marshall W. Kreuter, Sigrid G. Deeds, and Kay B. Partridge, has been effectively applied worldwide to address a broad range of health issues: risk factors like tobacco and lack of exercise, social determinants of health such as lack of access to transportation and safe housing, and major disease challenges like heart disease and guinea worm disease. In Health Program Planning, Implementation, and Evaluation, Green and his team of senior editors and chapter authors combine their expertise to offer a high-level guide to public health programming. This guide aligns with foundational public health competencies required by increasingly rigorous certification and accreditation standards. Driven by the coronavirus panTable of ContentsForeword by Jonathan E. FieldingPrefaceAcknowledgmentsAbout the EditorsContributors Part I. Hallmarks of the PRECEDE-PROCEED ModelChapter 1 A Model for Population Health Planning, Implementation, and EvaluationLawrence W. Green, Andrea Carlson Gielen, Marshall W. Kreuter, Darleen V. Peterson, and Judith M. Ottoson Chapter 2 Participation and Community Engagement in PlanningLawrence W. Green, Andrea Carlson Gielen, and Marshall W. KreuterPart II. PRECEDE-PROCEED Phases: Planning, Implementation, and EvaluationChapter 3 Social Assessment: Quality of LifeLawrence W. Green, Marshall W. Kreuter, and Andrea Carlson GielenChapter 4 Epidemiological Assessment I: Population HealthLawrence W. Green, Andrea Carlson Gielen, and Marshall W. KreuterChapter 5 Epidemiological Assessment II: Behavioral and Environmental FactorsLawrence W. Green, Marshall W. Kreuter, and Andrea Carlson GielenChapter 6 Educational and Ecological Assessment: Predisposing, Enabling, and Reinforcing FactorsMaría E. Fernández, Gerjo Kok, Guy Parcel, and Lawrence W. GreenChapter 7 Health Program and Policy Development I: Intervention StrategiesMichelle C. Kegler and Rodney LynChapter 8 Health Program and Policy Development II: Implementation StrategiesCam Escoffery and Lawrence W. GreenChapter 9 Health Program and Policy Development III: Evaluation StrategiesChris Y. Lovato and Judith M. OttosonPart III. Applications of PRECEDE-PROCEED in Specific SettingsIntroduction to PRECEDE-PROCEED ApplicationsChapter 10 Applications in Community SettingsAmelie G. Ramirez and Patricia ChalelaChapter 11 Applications in Occupational SettingsPaul Terry, Nico Pronk, and Shelley GoldenChapter 12 Applications in School SettingsLloyd J. Kolbe, Holly Hunt, and Faten Ben AbdelazizChapter 13 Applications in Health Care SettingsJohn P. Allegrante and Janey C. PetersonChapter 14 Applications in Communication TechnologyRobert S. GoldAppendixesA. Frequently Asked QuestionsAndrea Carlson Gielen and Vanya C. JonesB. Public Health Competencies by ChapterDarleen V. PetersonC. The Evaluation Standards: A ChecklistD. CDC Evaluation Framework Steps and PRECEDE-PROCEED PhasesE. Commonly Used Evaluation DesignsGlossaryIndex

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Book SynopsisTEXTBOOK OF EPIDEMIOLOGY The gold standard in epidemiological texts In the second edition of Textbook of Epidemiology, a distinguished team of researchers deliver an extensively updated and comprehensive exploration of epidemiological methods, illuminating the tools for studying the distribution and risk factors of health states and events in populations. An introduction to epidemiological methods with recent and broadly applicable examples End-of-chapter self-assessment questions for readers to check their understanding of key concepts, with answer keys and further enrichment materials available on a companion website A brand-new chapter covering methods for systematic review and meta-analysis Accessible material appropriate for clinical practitioners and researchers from around the world Perfect for professionals working in clinical medicine and public health, Textbook of Epidemiology will also earn a place in the libraries of allied health professionals seeking a one-stop resource or to reimmerse themselves in specific methodological topics and practices.Table of ContentsPreface xiAbout the companion website xiii1 Epidemiology 1 2 Frequency 13 3 Association 31 4 Study Design 47 5 Precision and Validity 65 6 Etiology and Causality 101 7 Genetic Epidemiology 117 8 Outbreak Epidemiology 133 9 Diagnostic and Prognostic Research 159 10 Intervention 191 11 Systematic Review and Meta-Analysis 207Answers to knowledge assessment questions 221Index 233

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Book SynopsisTrade ReviewDr. Alfredo Morabia's book takes us through many fascinating chapters in the history of public health....compelling.—Family MedicineTable of ContentsPreface1. Public Health2. Plague3. Smallpox4. Cholera5. Tuberculosis6. Cancer and Cardiovascular Diseases7. HIV/AIDS8. Social Determinants of Health9. 1918 Influenza And SARS/COVID-19Epilogue: The Public Health ApproachAppendix: How Old Is the Public Health Approach?AcknowledgementsReferencesNotesIndex

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Book SynopsisThis great-value pack offers students a definitive resource on clinical medicine.

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Book SynopsisOpioids. Concussions. Obesity. Climate change. America is a country of everyday crises -- big, long-spanning problems that persist, mostly unregulated, despite their toll on the country''s health and vitality. And for every case of government inaction on one of these issues, there is a set of familiar, doubtful refrains: The science is unclear. The data is inconclusive. Regulation is unjustified. It''s a slippery slope. Is it?The Triumph of Doubt traces the ascendance of science-for-hire in American life and government, from its origins in the tobacco industry in the 1950s to its current manifestations across government, public policy, and even professional sports. Well-heeled American corporations have long had a financial stake in undermining scientific consensus and manufacturing uncertainty; in The Triumph of Doubt, former Obama and Clinton official David Michaels details how bad science becomes public policy -- and where it''s happening today. Amid fraught conversations of alternative facts and truth decay, The Triumph of Doubt wields its unprecedented access to shine a light on the machinations and scope of manipulated science in American society. It is an urgent, revelatory work, one that promises to reorient conversations around science and the public good for the foreseeable future.Trade Review[Michaels] documents not only a shocking disregard for human welfare on the part of big business, but also a co-ordinated effort to compromise the culture of knowledge itself. * Times Literary Supplement *...chock full of good examples that were clearly researched (averaging over 30 references per chapter) and supplemented with Michaels' personal experiences. I think any scientist who wants to bridge the realm of research, policy, politics and ethics would benefit from reading this book. * JULIE POLLOCK, Chemistry World *David Michaels opens our eyes to the methods corporations employ that bend the facts of science in order to make a profit. * Chemistry World *Table of Contents1. Introduction 2. The Science of Deception 3. The Forever Chemical 4. The NFL's Head Doctors 5. A Spirited Denial 6. The Deal with Diesel 7. On Opioids 8. Deadly Dust 9. Working the Refs 10. Volkswagen's Other Bug 11. The Climate Denial Machine 12. Sickeningly Sweet 13. The Party Line 14. Science for Sale 15. Future in Doubt

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Book SynopsisInstant #1 New York Times and Wall Street Journal bestsellerNow in paperback and with a new afterword, Washington Post journalists Yasmeen Abutaleb and Damian Paletta''s definitive account of the Trump administration’s tragic mismanagement of the COVID-19 pandemic, and the chaos, incompetence, and craven politicization that has led to more than a half million American deaths and counting.Since the day Donald Trump was elected, his critics warned that an unexpected crisis would test the former reality-television host—and they predicted that the president would prove unable to meet the moment. In 2020, that crisis came to pass, with the outcomes more devastating and consequential than anyone dared to imagine. Nightmare Scenario is the complete story of Donald Trump’s handling—and mishandling—of the COVID-19 catastrophe, during the period of January 2020 up to Election Day that

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Book SynopsisTrade ReviewEarnest and exhaustive. — New York Times Book Review The best account we have so far of how Trump’s team botched the pandemic response so badly. . . . Significant . . . the book that should be an indispensable resource for future historians. . . . Deborah Birx offers more detail and nuance than anyone else. — The Atlantic There’s an underappreciated quiet heroism in the steadfast bureaucrat who day after day, for months on end, insists on seeking and spreading the truth. With Silent Invasion, Birx shows us she is a person of extraordinary tenacity who, armed with sound data and a deep sense of duty, fought corrupt forces to save lives as best she knew how. — Washington Post In-depth...In Silent Invasion, Birx reveals just how untenable her position was and, more importantly, what changes need to happen in order to win against the COVID-19 pandemic." — People

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Book SynopsisTHE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world.The fully revised and updated 2018 edition codifies the U.S. government''s most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities Special considerations for neTrade Review[The CDC Yellow BooK 2018] is a truly excellent and comprehensive resource * Andrew Berrington, Journal of Hospital Infection *Table of ContentsList of Boxes, Figures, Maps, and Tables, by Topic List of Maps Editorial Staff CDC Contributors External Contributors Acknowledgments In Memoriam: Dedication to Alan J. Magill Preface 1. Introduction Introduction to Travel Health & the Yellow Book Planning for Healthy Travel: CDC Travelers' Health Website and Mobile Applications Travel Epidemiology Perspectives: The Role of the Traveler in Translocation of Disease Perspectives: Why Guidelines Differ Air Travel Trends 2. The Pre-Travel Consultation The Pre-travel Consultation Perspectives: Travelers' Perception of Risk Perspectives: Prioritizing Care for the Resource-Limited Traveler Perspectives: The Need for a Cost Analysis of to Justify the Travel MedicineConsult General Recommendations for Vaccination & Immunoprophylaxis Interactions among Travel Vaccines & Drugs Perspectives: Fear of Vaccines Self-Treatable Conditions Travelers' Diarrhea Perspectives: Antibiotics in Travelers' Diarrhea -- Balancing the Risks & Benefits For the Record: A History of the Definition & Management of Travelers' Diarrhea Altitude Illness For the Record: A History of the Definition & Management of Altitude Illness Jet Lag Motion Sickness Respiratory Infections Counseling & Advice for Travelers Food & Water Precautions Perspectives: Prevention of Travelers' Diarrhea-It's Not Only WHAT You Eat & Drink Water Disinfection for Travelers Food Poisoning from Marine Toxins Protection against Mosquitoes, Ticks, & Other Arthropods Sun Exposure Problems with Heat & Cold Injury Prevention Safety & Security Animal-Associated Hazards Natural Disasters Environmental Hazards Scuba Diving Medical Tourism Discussing Complementary and/or Alternative Integrative Health Approaches with Travelers Deep Vein Thrombosis & Pulmonary Embolism Mental Health Travel Health Kits Perspectives: Pharmaceutical Quality & Counterfeit Falsified Drugs Obtaining Health Care Abroad for the Ill Traveler Travel Insurance, Travel Health Insurance, & Medical Evacuation Insurance 3. Infectious Diseases Related to Travel Amebiasis Angiostrongyliasis, Neurologic Anthrax B virus Bartonella Infections Brucellosis Campylobacteriosis Chikungunya Cholera Coccidioidomycosis Cryptosporidiosis Cutaneous Larva Migrans Cyclosporiasis Cysticercosis Dengue Diphtheria Ebola Virus Disease and Marburg Virus Disease Echinococcosis Escherichia coli, Diarrheagenic Fascioliasis Filariasis, Lymphatic Giardiasis Hand, Foot, & Mouth Disease Helicobacter pylori Helminths, Soil-Transmitted Hepatitis A Hepatitis B Hepatitis C Hepatitis E Histoplasmosis HIV Infection Influenza Japanese Encephalitis Legionellosis (Legionnaires' Disease & Pontiac Fever) Leishmaniasis, Cutaneous Leishmaniasis, Visceral Leptospirosis Lyme Disease Malaria For the Record: A History of Malaria Chemoprophylaxis Measles (Rubeola) Melioidosis Meningococcal Disease Middle East Respiratory Syndrome (MERS) Mumps Norovirus Onchocerciasis (River Blindness) Pertussis Pinworm (Enterobiasis, Oxyuriasis, Threadworm) Plague (Bubonic, Pneumonic, Septicemic) Pneumococcal Disease Poliomyelitis For the Record: A History of Polio Eradication Efforts Q Fever Rabies Perspectives: Intradermal Rabies Preexposure Immunization Rickettsial (Spotted & Typhus Fevers) & Related Infections, including Anaplasmosis & Ehrlichiosis Rubella Salmonellosis (Nontyphoidal) Sarcocystosis Scabies Schistosomiasis Sexually Transmitted Diseases Perspectives: Sex & Tourism Shigellosis Smallpox & Other Orthopoxvirus-Associated Infections Strongyloidiasis Taeniasis Tetanus Tickborne Encephalitis Toxoplasmosis Trypanosomiasis, African (Sleeping Sickness) Trypanosomiasis, American (Chagas Disease) Tuberculosis Perspectives: Tuberculin Skin Testing of Travelers Typhoid & Paratyphoid Fever Varicella (Chickenpox) Viral Hemorrhagic Fevers Yellow Fever For the Record: A History of Yellow Fever Vaccine Requirements Yersiniosis Zika Virus Yellow Fever & Malaria Information, by Country 4. Select Destinations Rationale for Select Destinations Africa & The Middle East East Africa: Safaris Saudi Arabia: Hajj/Umrah Pilgrimage South Africa Tanzania: Kilimanjaro The Americas & The Caribbean Brazil Cuba Dominican Republic Haiti Mexico Peru: Cusco-, Machu Picchu, and Other Regions Asia Burma (Myanmar) Cambodia China India Nepal Thailand Vietnam The Middle East & North Africa Egypt & Nile River Cruises Saudi Arabia: Hajj Pilgrimage 5. Post-Travel Evaluation General Approach to the Returned Traveler Fever in Returned Travelers Persistent Travelers' Diarrhea Skin & Soft Tissue Infections in Returned Travelers Screening Asymptomatic Returned Travelers 6. Conveyance & Transportation Issues Air Travel Cruise Ship Travel Perspectives: What to Expect when Traveling during an International Outbreak Death during Travel Taking Animals & Animal Products across International Borders 7. International Travel with Infants & Children Traveling Safely with Infants & Children Vaccine Recommendations for Infants & Children Travel & Breastfeeding International Adoption 8. Advising Travelers with Specific Needs Immunocompromised Travelers Travelers with Chronic Illnesses Pregnant Travelers Travelers with Disabilities Immigrants Returning Home to Visit Friends & Relatives (VFRs) Health Care Workers Advice for Air Crews Humanitarian Aid Workers Long-Term Travelers & Expatriates Perspectives: Malaria in Long-Term Travelers & Expatriates Last-Minute Travelers Special Considerations for US Military Deployments Study Abroad & Other International Student Travel Travel to Mass Gatherings Newly Arrived Immigrants & Refugees Wilderness and Expedition Medicine Work-Related Travel Immunocompromised Travelers Appendices Appendix A: Promoting Quality in the Practice of Travel Medicine Appendix B: Travel Vaccine Summary Table Appendix C: Migrant Health Resources Index Photo credits

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Book SynopsisThe first edition of The Struggle for Health was published in 1985 and was widely acclaimed by those seeking a broader and deeper political understanding of ill health, beyond the medical model of care. It was a revolutionary book, charting new ways of understanding and tackling the causes of ill health, and suggesting strategies to enable health for all. This second edition includes health problems that have emerged since the 1980s, notably HIV/AIDs, COVID-19, and other epidemics, and the increase in non-communicable diseases, such as cardiovascular disease and diabetes. It examines some of the health impacts of globalization, specifically on the food and pharmaceutical value chains, and considers the consequences of climate change on the health of populations. However, this edition does not depart from the core message of the original book: Health for All can only be achieved through a more equitable distribution of wealth, resources, and power. The Struggle for Health, Second EditioTrade ReviewThis book presents an accessible, comprehensive, and revealing analysis of the political economy of health. It provides a much-needed discussion of the alternatives to the pure capitalist approach to achieving equity in health outcomes. It provides hopeful solutions for the provision of comprehensive primary health care based on local needs. * Doody's Book Review *For years, attendees at global health conferences saw Sanders rise to ask, politely, pointed questions that many felt unable to ask. How had technology and metrics gained such prominence while engagement with communities and their local conditions and priorities were too often discounted? Sanders is now gone. But in this book, and in the work of People's Health Movement to which he devoted his final years, can be found the critical analyses, courage, and facts needed to stand up and speak truth to power. * Mary T Bassett, The Perspectives *Table of Contents1: Snapshots of (ill)health around the world 2: Global disease patterns 3: Health, population and inequality 4: The medical contribution 5: Health policies and health care in the context of neoliberal globalization 6: The commercialization of health care: Medicine, business and the state 7: Changing medicine, changing society

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Book SynopsisHealth Measurement Scales is the ultimate guide to appraising, developing, and validating measurement scales that are used in the health sciences. Written in a clear and practical style, this guide enables clinicians and researchers to both develop scales to measure subjective states and non-tangible health outcomes, as well as evaluate and differentiate among existing tools.Topics presented in the order that scales are constructed: how the individual items are developed, biases that can affect responses, various response options, how to select the best items in the set, how to combine them into a scale; and finally how to determine the reliability and validity of the scale.Fully updated to reflect recent developments in the field and the latest survey methods. The new edition contains updated information on generalizability theory and item response theory, and integration of qualitative research methods into scale design and testing. Including guidelines, appendices and checklists, this useful book is a must-read for any practitioner dealing with any kind of subjective measurement.

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Book SynopsisAMR is arguably one of the most severe long-term threats to human, animal, and environmental health. There is momentum for global political action around novel and emerging disease threats and Steering Against Superbugs contributes with original and insightful research to inform ongoing and future debates.Trade ReviewThis volume collects together key insights from across social sciences on AMR governance. AMR is now the third-leading underlying cause of death globally, which is why a global approach and global governance is necessary. Through a global perspective, the case studies in this volume highlight both successes and challenges of local, regional, and global governance for AMR. As we work together across the world to tackle the 'silent' AMR pandemic, I strongly recommend this book for all in the global and public health and policy sphere to help galvanise action to address the insidious and complex health emergency of AMR. * Professor Dame Sally Davies, UK Special Envoy on Antimicrobial Resistance (AMR) *Steering Against Superbugs comprehensively unpacks the root social drivers of antimicrobial resistance and masterfully situates these drivers in their cultural, historical and political contexts. Rubin, Baekkeskov, and Munkholm have brought together some of the world's leading thinkers in this field and have pro¬vided us with some of the best ideas yet to tackle this intensifying global health challenge that already kills more than 1.2 million people each year. * Professor Steven J. Hoffman, Director of the Global Strategy Lab and the WHO Collaborating Centre on Global Governance of Antimicrobial Resistance, York University, Canada *This exciting volume achieves what many have been waiting for: a compen¬dium of social science approaches to antimicrobial resistance. With a focus on governance, the authors demonstrate the strengths of different disciplines by providing evidence at multiple scales of the ways in which antibiotics, and drug resistance, is-and can be-governed. From clinics, to bednets, to global policy spaces, the book introduces the reader to detailed case studies that enlighten and awaken interest in the multiple dimensions that make up the complex challenge of antimicrobial resistance globally. * Professor Clare Chandler, Anthropology of Antimicrobial Resistance lead and founding Director, AMR Centre, London School of Hygiene & Tropical Medicine. *Microbes, humans, One Health, and the interplay between them through AMR. This book introduces the reader to the conceptual issues of AMR, and then steers her through governance challenges, One Health aspects, global awareness, advocacy and regulatory matters. This is essential reading, not just for those working in this critical field but also for policy- makers, healthcare leaders, One Health professionals, and the wider community-providing an armament of knowledge, insight, and perspectives in the fight against AMR. * Professor & Head Sujith J Chandy, Department of Pharmacology & Clinical Pharmacology, Christian Medical College Vellore, India *Table of Contents1: Steering against Superbugs: Research agenda and four perspectives for global governance Part I: Framing and conceptualizing AMR 2: Pills and Politics - a historical analysis of international antibiotic regulation since 1945 3: Global eradicationism and AMR 4: Conceptualizing AMR as a creeping disaster in terms of pace and space Part II: Coordination and leadership in AMR governance 5: Combatting AMR in the EU - governmental dimensions 6: Contested governance of collective action against AMR in the EU 7: What would it take to move the global AMR agenda forward in the Global South? Part III: AMR Governance from below 8: The individual in global and national AMR governance 9: Governing AMR: a case for considering governance 10: A sociological look beyond the surface of the national action plans against AMR: How state professionals adjust to global governance Part IV: A One Health Perspective on AMR 11: One Health and AMR governance 12: From policy to practice: Challenges and opportunities for cross-sectoral AMR mitigation and response efforts 13: Joint action against AMR with a One Health perspective Part V: Global advocacy and awareness of AMR 14: Policy entrepreneurship and problem brokering in the global governance of AMR 15: Global attention to Antimicrobial Resistance and Climate Change in the era of Social Media 16: The policy context for responses to antimicrobial resistance in India Part VI: Regulatory responses to AMR 17: A case for the global governance of AMR by regulating the pharmaceutical supply chain 18: Sustainable procurement of pharmaceuticals - a tool to combat global antimicrobial resistance 19: International Law and AMR: Learning from 15 years implementing the International Health Regulations

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Trade Review"A fluent text . . . This timely book helps fill an important gap." --Journal of the American Medical Association "Clear and direct . . . Fulfills its promise to provide epidemiologists and statisticians with a useful resource on a topic that had previously been neglected. It could serve as a most useful addition to anyone designing or evaluating case-control studies." --American Statistical Association Newsletter "The language is clear, there are many examples, and the text forms a uniform discussion of a wide range of topics which up until now could be covered only by review of the original epidemiologic and biostatistical literature." --Epidemiology Monitor "A fluent text . . . This timely book helps fill an important gap." --Journal of the American Medical Association "Clear and direct . . . Fulfills its promise to provide epidemiologists and statisticians with a useful resource on a topic that had previously been neglected. It could serve as a most useful addition to anyone designing or evaluating case-control studies." --American Statistical Association Newsletter "The language is clear, there are many examples, and the text forms a uniform discussion of a wide range of topics which up until now could be covered only by review of the original epidemiologic and biostatistical literature." --Epidemiology Monitor

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Book SynopsisThe book offers a comprehensive view of the health of Native Americans in the United States and Canada. The author emphasizes the interaction of biology and culture in disease causation, distribution, and control.Trade Review'without peer as an introduction to the health problems of the indigenous peoples of North America ... I will recommend it to undergraduate, graduate, and medical students seeking information on Indian health. Physicians and public health professionals serving Native American populations, even those with years of experience, will have much to learn from the book, I certainly did.' Jonathan R. Sugarman, JAMA, February 1995, Vol. 273, No. 6an excellent review of the literature with careful attention to the limitations inherent in much of the research ... This book is a valuable reference for researchers and health professionals working with Native communities. * Canadian Journal of Public Health, Vol. 86, No. 3, May/June 1995 *Table of Contents1: An Introduction to Native Americans 2: An Overview of Population and Health 3: Decline and Persistence of Infectious Diseases 4: Emergence of Chronic Diseases (I) 5: Emergence of Chronic Diseases (II) 6: Injuries and Social Pathologies 7: Towards a Biocultural Epidemiology

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Book SynopsisThis text deals with the design and accuracy of epidemiological studies. It gives students a clear understanding of the research strategies used in experimental and non-experimental studies to ask the right questions, select the study population and follow-up period, obtain information on exposures, follow up disease occurrence, etc.Trade Review"A very useful book, and I am looking forward to using it for teaching and discussion groups....I recommend the book highly."--Doody's Health Sciences Book Review JournalTable of Contents1: Basic Concepts 2: Asking the Right Questions 3: Selecting the Study Population and Follow-up Period 4: Obtaining Information on Exposure 5: Follow-up of Disease Occurrence 6: Sampling from the Base (Case-referent Studies) 7: Assignment of Exposure (Experimental Strategies) 8: General Exercises

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Book SynopsisThis is the first comprehensive text about the design and analysis of community or group-randomized trials, which are usually done to evaluate the effect of health promotion efforts. It reviews the underlying issues, describes the most widely used research designs, and presents the many approaches to analysis that are now available.Trade Review"This book is an important addition to any public health or medical library. It is well-written and much needed."--Doody's JournalTable of Contents1. Introduction ; 2. Planning the Trials ; 3. Research Design ; 4. Planning the Analysis ; 5. Analysis for Nested Cross-Sectional Designs ; 6. Analysis for Nested-Cohort Designs ; 7. Applications of Analyses for Nested Cross-Sectional Designs ; 8. Applications of Analyses for Nested-Cohort Designs ; 9. Sample Size, Detectable Difference and Power ; 10. Case Studies

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Book SynopsisPhysical activity clearly is associated with decreased risk of many chronic diseases, as well as with longer life. Utilizing modern epidemiologic methods, studies of physical activity and health have been conducted since the 1940s. However physical inactivity did not gain widespread acknowledgement as a major risk factor for poor health until 1992, when the American Heart Association recognized it as a risk factor for heart disease, on par with risk factors such as smoking. This text includes chapters describing the associations between physical activity and major diseases. With a major emphasis on the methods underpinning studies that can be conducted to elucidate these associations, this book is an important guide for those performing the informative epidemiologic studies needed to reduce the increasing number of people diagnosed with chronic disease due to inactivity.Trade ReviewA thorough and thought-provoking overview of the rapidly evolving field of physical activity and inactivity measurement and of data analytic techniques... an excellent companion for physical activity researchers and students alike. * American Journal of Epidemiology *Table of ContentsCONTENTS; CONTRIBUTORS; EPIDEMIOLOGIC METHODS, I-MIN LEE, RALPH S. PAFFENBARGER, JR; EPIDEMIOLOGIC DATA, SECTION EDITOR: JOANN MANSON; PROMOTING PHYSICAL ACTIVITY, SECTION EDITOR: STEVEN N. BLAIR

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Book SynopsisTwo decades after the third edition of Lilienfeld''s Foundations of Epidemiology advanced the teaching of epidemiology, this completely revised fourth edition offers a new and innovative approach for future generations of students in population health. Authored by two longtime educators in epidemiology, this all-new Foundations frames the field''s fundamental concepts within a mix of classic examples and recent case studies, as well the inclusion of recently developed measures now finding commonplace usage in the field. The result is a comprehensive introduction to modern epidemiology accessible to readers of all backgrounds and interests.Features in this new Foundations include:- Coverage of all the fundamentals of epidemiology, including measuring health status, characteristics of outbreaks, design and construct of epidemiologic studies- Exercises to check understanding- Chapters devoted to clinical epidemiology, fieldwork, evidence-based medicine, and evidence-based public health contextualize epidemiology and its place in medicine and societyDevoid of the digressions and inaccessibility that characterize many other introductory epidemiology texts, this new Foundations of Epidemiology will inform thinking and learning in the population sciences for decades to come. It is affordable, comprehensive, and enjoyable to read, one not likely to sit on the shelf collecting dust but to be consulted over time as one would when seeking guidance from a wise friend or mentor.Table of ContentsI INTRODUCTION TO EPIDEMIOLOGY ; 1. Laying the Foundations: The Epidemiologic Approach ; 2. Threads of Epidemiologic History ; 3. Selected Epidemiologic Concepts of Disease ; 4. Inferring Causal Relationships from Epidemiologic Studies ; II DEMOGRAPHIC STUDIES ; 5. Vital Statistics ; 6. Vital Statistics: Studies ; 7. Morbidity Statistics ; 8. Morbidity Statistics: Studies ; III EPIDEMIOLOGIC STUDIES ; 9. Observational Studies I: Cohort Studies ; 10. Observational Studies II: Case-Control Studies ; 11. Experimental Studies I: Randomized Controlled Trials ; 12. Experimental Studies II: Community and Cluster Randomized Trials ; IV USING EPIDEMIOLOGIC INFORMATION ; 13. Clinical Applications ; 14. Field Epidemiology ; 15. Evidence-Based Practices ; APPENDICES ; 1. Guide to Reading the Epidemiologic Literature ; 2. Standards for Reporting the Results of Epidemiologic and Health-Related Studies ; 3. Answers to Problem Sets ; INDEX

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Book SynopsisFor over half a century, the CDC Yellow Book has been a trusted resource, providing international travelers and clinicians with expert guidance for safe and healthy travel abroad. Along with disease-specific prevention and treatment recommendations, this comprehensive reference text provides readers with the background and context needed to understand and address health threats associated with all types of international travel.FEATURED IN THIS EDITION: Precautions for international travelers during the coronavirus disease 2019 (COVID-19) pandemic, including links to updated information on related CDC and US government websites Updates on practicing travel medicine in a virtual environment New standalone vaccine tables for bacterial and viral diseases with links to the relevant Advisory Committee on Immunization Practices and US FDA websites Safe international travel with pets and service animals Advice for obtaining healthcare abroad including guidance on different types of travel insurance Guidelines for self-treating common travel conditions including altitude illness, jet lag, motion sickness, and travelers'' diarrhea Detailed maps showing the distribution of travel-associated infections and diseases, including dengue and meningococcal meningitis Country-specific mosquito avoidance, yellow fever vaccine, and malaria prevention recommendations Food and drink precautions, plus updated water-disinfection techniques Expanded content on safe international travel for specific groups including: LGBTQ+ individuals, highly allergic travelers, travelers with substance use issues, and medical tourists Specialized recommendations for non-leisure travelers, study abroad, work-related travel, and travel to mass gatherings Health insights for 14 popular destinations and itineraries in Africa and the Middle East, the Americas and the Caribbean, and Asia Considerations for newly arrived adoptees, immigrants, and refugeesTrade ReviewA beloved travel must-have for the intrepid wanderer." -Publishers WeeklyA truly excellent and comprehensive resource." -Journal of Hospital InfectionThis is a very well-written book that provides a great explanation of the core principles of travel medicine. This [2020] edition includes updated recommendations on some of the vaccines, such as the yellow fever vaccine. An understanding of the concepts in this book serves the needs of clinicians who aim to conquer the outbreaks of infectious diseases associated with travel. (Weighted Numerical Score: 100 - 5 Stars!) * Manasa Velagapudi, Doodys *This is the gold-standard in the field of travel medicine due to its enormous scope, expertise, and ease of use. * Kenneth Schaefle, MD, Albert Einstein College of Medicine, Doody's Book Review *Table of ContentsList of Maps, by topic CDC Contributors External Contributors Acknowledgments Preface Dedication 1 Introduction Disease Patterns in Travelers ...perspectives: Why Guidelines Differ Maps & Travel Medicine Improving the Quality of Travel Medicine through Education & Training 2 Preparing International Travelers The Pretravel Consultation ...perspectives: Travelers' Perception of Risk Vaccination & Immunoprophylaxis-General Principles Interactions Between Travel Vaccines & Drugs Yellow Fever Vaccine & Malaria Prevention Information, by Country Travelers' Diarrhea ...perspectives: Antibiotics in Travelers' Diarrhea-Balancing Benefit & Risk Food & Water Precautions Water Disinfection Travel Health Kits Last-Minute Travelers Mental Health LGBTQ+ Travelers Complementary & Integrative Health Approaches to Travel Wellness Prioritizing Care for Resource-Limited Travelers Telemedicine ...perspectives: Risk Management Issues in Travel Medicine 3 Travelers with Additional Considerations Immunocompromised Travelers Travelers with Disabilities Travelers with Chronic Illnesses Highly Allergic Travelers Substance Use & Substance Use Disorders 4 Environmental Hazards & Risks Sun Exposure Extremes of Temperature Air Quality & Ionizing Radiation Scuba Diving: Decompression Illness & Other Dive-Related Injuries High Elevation Travel & Altitude Illness Mosquitoes, Ticks & Other Arthropods Zoonotic Exposures: Bites, Stings, Scratches & Other Hazards Zoonoses-The One Health Approach Bringing Animals & Animal Products into the United States Food Poisoning from Marine Toxins Safety & Security Overseas Injury & Trauma Death During Travel 5 Travel-Associated Infections & Diseases BACTERIAL Vaccine-Preventable Diseases: Bacterial Anthrax Bartonella Infections Brucellosis Campylobacteriosis Cholera Diphtheria Escherichia coli, Diarrheagenic Helicobacter pylori Legionnaires' Disease & Pontiac Fever Leptospirosis Lyme Disease Melioidosis Meningococcal Disease Pertussis / Whooping Cough Plague Pneumococcal Disease Q Fever Rickettsial Diseases Salmonellosis, Nontyphoidal Shigellosis Tetanus Tuberculosis ...perspectives: Testing Travelers for Mycobacterium tuberculosis Infection Typhoid & Paratyphoid Fever Yersiniosis VIRAL Vaccine-Preventable Diseases: Viral B Virus Chikungunya COVID-19 Dengue Hand, Foot & Mouth Disease Henipavirus Infections Hepatitis A Hepatitis B Hepatitis C Hepatitis E Human Immunodeficiency Virus / HIV Influenza Japanese Encephalitis Middle East Respiratory Syndrome / MERS Mumps Norovirus Poliomyelitis Rabies ...perspectives: Rabies Immunization Rubella Rubeola / Measles Smallpox & Other Orthopoxvirus-Associated Infections Tick-Borne Encephalitis Varicella / Chickenpox Viral Hemorrhagic Fevers Yellow Fever Zika PARASITIC Amebiasis Angiostrongyliasis Cryptosporidiosis Cutaneous Larva Migrans Cyclosporiasis Cysticercosis Echinococcosis Enterobiasis / Pinworm Filariasis, Lymphatic Flukes, Liver Flukes, Lung Giardiasis Helminths, Soil-Transmitted Leishmaniasis, Cutaneous Leishmaniasis, Visceral Malaria Onchocerciasis / River Blindness Sarcocystosis Scabies Schistosomiasis Strongyloidiasis Taeniasis Toxoplasmosis Trypanosomiasis, African Trypanosomiasis, American / Chagas Disease FUNGAL Coccidioidomycosis / Valley Fever Histoplasmosis 6 Health Care Abroad Travel Insurance, Travel Health Insurance & Medical Evacuation Insurance Obtaining Health Care Abroad ...perspectives: Avoiding Poorly Regulated Medicines & Medical Products during Travel Medical Tourism 7 Family Travel Pregnant Travelers Travel & Breastfeeding Traveling Safely with Infants & Children Vaccine Recommendations for Infants & Children International Adoption Traveling with Pets & Service Animals 8 Travel by Air, Land & Sea Air Travel ...perspectives: Responding to Medical Emergencies when Flying Deep Vein Thrombosis & Pulmonary Embolism Jet Lag Road & Traffic Safety Cruise Ship Travel Motion Sickness Airplanes & Cruise Ships: Illness & Death Reporting & Public Health Interventions 9 Travel for Work & Other Reasons The International Business Traveler Advice for Aircrew ...perspectives: People Who Fly for a Living-Health Myths & Realities Health Care Workers, Including Public Health Researchers & Medical Laboratorians Humanitarian Aid Workers United States Military Deployments Long-Term Travelers & Expatriates Study Abroad & Other International Student Travel Visiting Friends & Relatives: VFR Travel Mass Gatherings Adventure Travel Sex & Travel 10 Popular Itineraries The Rationale for Popular Itineraries AFRICA & THE MIDDLE EAST African Safaris Saudi Arabia: Hajj & Umrah Pilgrimages South Africa Tanzania & Zanzibar THE AMERICAS & THE CARIBBEAN Brazil Dominican Republic Haiti Mexico Peru ASIA Burma (Myanmar) China India Nepal Thailand 11 Posttravel Evaluation General Approach to the Returned Traveler Rapid Diagnostic Tests for Infectious Diseases ...perspectives: Screening Asymptomatic Returned Travelers Fever in the Returned Traveler Antimicrobial Resistance Respiratory Infections Persistent Diarrhea in Returned Travelers Dermatological Conditions ...perspectives: Delusional Parasitosis Sexually Transmitted Infections Newly Arrived Immigrants, Refugees & Other Migrants

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Book SynopsisWell-heeled American corporations have long had a financial stake in undermining scientific consensus and manufacturing uncertainty. In The Triumph of Doubt, former Obama and Clinton official David Michaels details how corrupt science becomes public policy -- and where it''s happening today. Opioids. Concussions. Obesity. Climate Change.America is a country of everyday crises -- big, long-spanning problems that persist despite their toll on the country''s health. And for every case of government inaction on one of these issues, there is a set of familiar, doubtful refrains: The science is unclear. The data are inconclusive. Regulation is unjustified. It''s a slippery slope.Is it?The Triumph of Doubt traces the ascendance of science-for-hire in American life and government, from its origins in the tobacco industry in the 1950s to its current manifestations across government, public policy, and even professional sports. Amid fraught conversations of alternative facts and truth decay, The Triumph of Doubt wields its unprecedented access to shine a light on the machinations and scope of manipulated science in American society. It is an urgent, revelatory work, one that promises to reorient conversations around science and the public good for the foreseeable future.Trade Review[Michaels] documents not only a shocking disregard for human welfare on the part of big business, but also a co-ordinated effort to compromise the culture of knowledge itself. * Times Literary Supplement *...chock full of good examples that were clearly researched (averaging over 30 references per chapter) and supplemented with Michaels' personal experiences. I think any scientist who wants to bridge the realm of research, policy, politics and ethics would benefit from reading this book. * JULIE POLLOCK, Chemistry World *It is so refreshing to read David Michaels' The Triumph of Doubt. He has the facts researched, vetted and thoroughly cited, and is not afraid to lay blame, call people liars and companies frauds. * San Francisco Review of Books *David Michaels opens our eyes to the methods corporations employ that bend the facts of science in order to make a profit. * Chemistry World *David Michaels is that rare combination: the fearless expert. He not only knows where the bodies are buried, he knows who buried them. The Triumph of Doubt and its predecessor, Doubt Is Their Product, are timely, readable, and essential guides for anyone seeking to understand how the corruption of science is damaging the health of everyone from football players and factory workers to soda drinkers and truck drivers-in short, anyone with a pulse. * Dan Fagin, author of the Pulitzer Prize-winning Toms River *David Michaels lays bare the dark money and the corporate science racket that kept the lethalities of tobacco, asbestos, lead, silica, pesticides, and scores of other life- and health-destroying products on the market and in the workplace, escaping the reach of the law. He names names of people and companies fronted by their so-called 'product defense' business and its corporate attorney enablers; delays, obfuscation, falsehood, and retaliation against ethical whistleblowers are the coins of their insidious realms. This book is written to get you angry enough to want to learn how to defend yourselves, your communities, and our vulnerable planet. Let it grip you toward detection and defiance." * Ralph Nader *As a society, it's vital we properly debate issues using data and research. The Triumph of Doubt, David Michaels's wonderfully deep dive into the well-funded war on scientific consensus and certainty, makes the stakes clear: our planet. Read this." * Adam Savage, Mythbusters *No one has done more to expose the deep corruption in American safety regulation that harms us all-and especially our kids. After spending seven years as America's chief safety regulator, David Michaels offers a beautifully crafted argument for how much more we need to do. Required-if frightening-reading for anyone who cares about a clean and safe environment for America and the world." * Lawrence Lessig, author of Fidelity and Constraint *A page-turner-one you'll wish was fiction. From hired guns to dark money, The Triumph of Doubt unravels corporations' playbook for deceiving the public through misinformation.^ * Mona Hanna-Attisha, author of What the Eyes Don't See *The Triumph of Doubt is an industry-by-industry account of how corporations manipulate science and scientists to promote profits, not public health. Nothing less than democracy is at stake here, and we all should be responding right away to David Michaels' call for action. * Marion Nestle, author of Unsavory Truth *It takes real courage to speak out against entrenched corporate interests and big industry. I saw that courage firsthand when I worked alongside Dr. Michaels in the Obama administration to protect workers at construction sites from cancer-causing silica dust. The Triumph of Doubt doesn't just tell the story of how we overcame the falsehoods of industry-funded studies, it shines a disinfecting light on the ways corporations obscure the truth and downplay risk to pump up their bottom line. This is a must-read." * Tom Perez, former U.S. Labor Secretary *A compelling and necessary work for anyone interested in the truth and those who seek to bury it. Michaels details the methods used by those in power to hide the truth-and the moral bankruptcy at work when they do so." * Demaurice Smith, National Football League Players Association Executive Director *As a third-generation coal miner from a family who has suffered the deadly consequences of Black Lung, I know firsthand that worker safety should never be politicized. David Michaels's book is a must-read for business, labor and the scientific community." * Richard Trumka, AFL-CIO President *David Michaels provides well-written evidence in his book about how corporations that produce dangerous products-tobacco, big oil, chemicals, pharmaceuticals-use 'product defense' science to sow doubt about the hazards hidden in their products to consumers. His evidence highlights the important role unbiased government scientists play in protecting the public health of Americans and our environment from exposure to toxic materials and from corporate deceit. * Senator Tom Udall *From the pharmaceutical industry's role in the opioid crisis to the Koch brothers' climate denial apparatus, Michaels examines big industry's jarring history of manufacturing false scientific doubt in the name of profit. This is an important book that will serve as a tool in exposing corporate deceit. * Senator Sheldon Whitehouse *Whether it's the tobacco industry, the pharmaceutical industry, or the fossil fuel industry, vested interests have repeatedly sought to attack and discredit scientific findings that have revealed the public endangerment by their products. David Michaels should know-he's been fighting the good fight for more than a decade to expose the bad actors and bring them to justice. Read this book to learn what we're up against and how to fight back. * Michael E. Mann, author of The Madhouse Effect *Poisoning the well of public debate is the ultimate act of cynicism. As David Michaels makes breathtakingly clear, one industry after another has lied and manipulated in order to make more money, and the rest of us have borne the terrible costs." * Bill McKibben, author of Falter *While the truth can be inconvenient, corporations and government leaders cannot continue to manufacture alternative narratives that place their interests and profits above our humanity; this culture, if left unchallenged, will result in our doom. The Triumph of Doubt reminds us that there can only be one truth." * Bennet Omalu, author of Truth Doesn't Have a Side *Few people have done more to document disinformation about science than David Michaels. His new book is an important addition to the growing literature on doubt, disinformation, and deception. * Naomi Oreskes, author of Merchants of Doubt *In the NFL, team doctors answer to the organization; players joke that it's like Dracula running the blood bank. It's a microcosm of what David Michaels brilliantly illuminates in The Triumph of Doubt: When corporations manipulate science and launch marketing campaigns to sow doubt, they ensure human suffering. Michaels's work is vital reading for everyone to understand these industry tactics. * Chris Borland, former NFL player *Scientist, public servant, and passionate advocate for health and safety, Michaels has written an absorbing sequel to his path-breaking work on manufactured doubt. He documents how powerful corporations have turned 'product defense' into a new political strategy, using dark money to pummel good science and keep dangerous products on the market. A must-read in the fight to restore public trust in regulatory science." * Sheila Jasanoff, Harvard Kennedy School *Driven by scientific interest, The Triumph of Doubt is a measured but passionate argument for protecting the public from harmful substances via federal oversight." * Foreword Reviews *[An] excoriating account of the corporate denial industry... It is a brave and important book, raising the alarm about the systemic corruption of science. * Felicity Lawrence, Nature *A tour de force that examines how frequently, and easily, science has been manipulated to discredit expertise and accountability on issues ranging from obesity and concussions to opioids and climate change. * Science *David Michaels shows that Big Tobacco's well-known denial tactics have not faded into history, but instead have become an integral part of corporate America's standard business practices. * Undark Magazine *A no-holds barred page-turner. In a series of case studies, it names names and describes how powerful players prioritize a requirement of absolute proof over precaution when it comes to exposures' impacts on human health. * Union of Concerned Scientists *[Michaels'] book is a timely, must read indictment of product defense 'science.'" * Pittsburgh Post-Gazette *David Michaels opens our eyes to the methods corporations employ that bend the facts of science in order to make a profit. * Chemistry World *[A] close look at how powerful corporations fund junk science and misinformation campaigns in order to obscure evidence and undercut regulatory efforts." * Vox *The Triumph of Doubt is a carefully researched review of corporate-funded strategies and practices that undermine public health policies of all kinds. And while it sometimes makes one's blood boil, it is still a gripping read. * New Solutions *[An] excoriating account of the corporate denial industry.... It is a brave and important book, raising the alarm about the systemic corruption of science. * Nature *Table of Contents1. Introduction 2. The Science of Deception 3. The Forever Chemical 4. The NFL's Head Doctors 5. A Spirited Denial 6. The Deal with Diesel 7. On Opioids 8. Deadly Dust 9. Working the Refs 10. Volkswagen's Other Bug 11. The Climate Denial Machine 12. Sickeningly Sweet 13. The Party Line 14. Science for Sale 15. Future in Doubt

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Book SynopsisThe field of molecular evolution has experienced explosive growth in recent years due to the rapid accumulation of genetic sequence data, continuous improvements to computer hardware and software, and the development of sophisticated analytical methods. The increasing availability of large genomic data sets requires powerful statistical methods to analyse and interpret them, generating both computational and conceptual challenges for the field.Computational Molecular Evolution provides an up-to-date and comprehensive coverage of modern statistical and computational methods used in molecular evolutionary analysis, such as maximum likelihood and Bayesian statistics. Yang describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes. The book emphasizes essential concepts rather than mathematical proofs. It includes detailed derivationsTrade ReviewWhat sets this books apart is the authority and thoughtfulness with which it is written, the thorough coverage of the relevant literature, and the great care that has been taken in the computational examples to compare different methods on the same set of data, and to present the results clearly. It will be an invaluable resource both for new graduate students and established researchers. It will be a major source for insight and enormously helpful for anyone who wants to understand molecular phylogenies. * The Quarterly Review of Biology *Table of ContentsPREFACE ; APPENDIXES ; REFERENCE

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