Regenerative medicine: stem cells Books

Book SynopsisThe normal functioning of the human female reproductive system is sacrosanct, as it allows for the essential nurturing of offspring. Conditions such as endometriosis and fibroid formation can have devastating consequences to the progeny, as well as the parents, both physically and mentally. This book has several chapters that deal with the role of stem cells in the safer outcome of pregnancies. Mesenchymal stem cells continue to make waves as various researchers dwell on their low immunogenicity to prevent graft rejection when used for therapeutic strategies. Dental pulp-derived stem cells are being sought after to address many therapies. However, researchers must exercise ethical caution to avoid resorting to pulling out the teeth of live, healthy animals, including those qualified for pets. The efficacy of cancer treatments with naturally occurring plant-derived substances and the characterization of cancer stem cells and lesions continue to engage researchers of this ever-perennial disease and its potentially lethal pathology. Stem cells to replenish the pancreatic islet cells from induced pluripotent stem cells are an actively pursued subject in regenerative medicine for diabetes patients. Stem cells in immune responses are also attracting researchers to investigate immune tolerance and autoimmunity.Table of ContentsPreface; Stem Cells of Female Reproductive System: Endometrium vs Fallopian Tube; Anti-angiogenic Potential of Itraconazole and Its Reversal by Endometrial Stem Cells Using Chick Embryo Model; Intrauterine Infusion of Human Autologous Peripheral Blood Mononuclear Cells Improves In Vitro Fertilization Success in Infertile Women; Development and Characterization of Hematopoietic Stem Cells from Human Embryonic Stem Cells; Mutation Analysis of MTHFR Gene in Indian Women with Unexplained Recurrent Miscarriages; Folic Acid Supplementation Improves Pregnancy Outcomes; Comparison of the Proliferation Potential of Bone Marrow and Adipose- Derived Mesenchymal Stem Cells Cultivating on Human Amniotic Membrane; Efficacy of the Mesenchymal Stem Cells Therapy Combined with Core Decompression in Avascular Necrosis of the Femoral Head: A Systematic Review and Meta-analysis of Clinical Trials; Proliferation Capacity and Osteogenic Potential of Human Gingival Stem Cells versus Human Dental Pulp Stem Cells; Comparison between the Effect of MTA and Biodentine on Proliferation and Odontogenic Differentiation of Dental Pulp Stem Cells (In Vitro Study); The Monomeric Resins TEGDMA and HEMA Regulate the Transcriptional Control of Matrix Metalloproteinases MMP-2 and MMP-9, in Human Pulp Fibroblasts and Mesenchymal Stem Cells; Effect of Dental Stem Cells on T Cell Proliferation; Amount of Bone Morphogenetic Protein-2, Epidermal Growth Factor, and Vascular Endothelial Growth Factor in Adipose Tissue, Umbilical Cord, and Bone Marrow Mesenchymal Stem Cell Derived Secretome: An In-Vitro Study; Identified Cancer Stem Cells (CSCs) in Ex- Vivo Cultured Acute Lymphoid Leukemia (B-ALL) Cells; Role of Simarouba glauca DC Plant in Cancer: A Short Review; Study of Histomorphological Spectrum of Thyroid Lesions in Thyroidectomy Specimens, Along with Cytological Correlation: Cross Sectional Study from 2015 to 2018; Generation of Pancreatic β Cells from Peripheral Blood Mononucleocytes Derived Induced Pluripotent Stem Cells; Stem Cells: An Exciting Avenue for Diabetes Mellitus; Regenerations Role in the Development of Desensitization and Immunological Tolerance; Features of the Immune Response to Ones Own Antigens and Foreign Antigens; Regenerative Approach to the Treatment of COVID-19 Patients; Medical Applications of Infrared Thermography: A Narrative Review; Index.

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Book SynopsisThis book provides the first comprehensive account of multilineage-differentiating stress-enduring (Muse) cells, a pluripotent and non-tumorigenic subpopulation of mesenchymal stem cells (MSCs) that have the ability to detect damage signals, migrate to damaged sites, and spontaneously differentiate into cells compatible with the affected tissue, thereby enabling repair of all tissue types. The coverage encompasses everything from the basic properties of Muse cells to their tissue repair effects and potential clinical applications—for example, in acute myocardial infarction, stroke, skin injuries and ulcers, renal failure, and liver disease. An important technical chapter provides a practical and precise protocol for the isolation of Muse cells, which will enable readers to use Muse cells in their own research. In offering fascinating insights into the strategic organization of the body’s reparative function and explaining how full utilization of Muse cells may significantly enhance the effectiveness of MSC treatment, the book will be of high value for Ph.D. students, postdocs, basic researchers, clinical doctors, and industrial developers. Table of ContentsForeword.- Preface.- Chapter 1 The Muse cell discovery; thanks to wine and science.- Chapter 2 Basic characteristics of Muse cells.- Chapter 3 Muse cells are endogenous reparative stem cells.- Chapter 4 Protocols for isolation and evaluation of Muse cells.- Chapter 5 Stem cells and DNA repair capacity: Muse stem cells are among the best performers.- Chapter 6 Immunomodulatory properties and potential therapeutic benefits of Muse cells administration in diabetes.- Chapter 7 The Role of the Mitochondria in the Evolution of Stem Cells, Including MUSE Stem Cells, and Their Biology.- Chapter 8 Acute myocardial infarction, cardioprotection, and Muse cells.- Chapter 9 Application of Muse Cell Therapy to Stroke.- Chapter 10 Muse Cell – A New Paradigm for Cell Therapy and Regenerative Homeostasis in Ischemic Stroke.- Chapter 11 Application of Muse cell therapy for kidney diseases.- Chapter 12 Liver regeneration supported by Muse cells.- Chapter 13 Current cell based therapies in the chronic liver diseases.- Chapter 14 Artificial pigmented-human skin created by Muse cells.- Chapter 15 Muse Cells and Aortic Aneurysm.- Chapter 16 Muse cells and ischemia-reperfusion lung injury.- Chapter 17 Clinical trials of Muse cells.- Chapter 18 Future of Muse Cells.

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Book SynopsisIs there a way to fight back against 'incurable' disease? California thought so — and put its money where its mind was — three billion dollars' worth! And when that was gone, how about five and a half billion dollars more — to build and expand the California Institute for Regenerative Medicine?For some, science excites; it is the great adventure, to challenge the impossible: like a real-life battle with a giant squid, or the proposed disassembly of the Eiffel Tower, or ejecting from a jet in the sky, from a height greater than Mount Everest.For others, regenerative medicine is a mystery — could the urge to do murder have a genetic cause — which might be reduced?And for everyone, there is the fight to protect our loved ones' lives— 133 million of us, suffering from chronic disease — from America alone, a colossal cost of $3 trillion dollars last year.An epic battle, 'Science, Politics, Stem Cells and Genes: CALIFORNIA'S WAR ON CHRONIC DISEASE' takes the reader behind the scenes.An award-winning teacher, Reed shares science in stories — including the systematic assault on Alzheimer's disease, cancer, autism, epilepsy, liver failure, schizophrenia, obesity, stroke, sickle cell, arthritis, blindness, paralysis, kidney failure, ALS, aging, and much, much more.Readers can expect a greater understanding of the intricate adventure of stem cell research, as well as the political wrestling it took to make progress possible — that California's effort may benefit the world.From early research to clinical trials, America should take pride in the accomplishments of the California Institute for Regenerative Medicine.Read on.

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Book SynopsisA scientist assesses the potential of stem cell therapies for treating such brain disorders as stroke, Alzheimer's disease, and Parkinson's disease.Stem cell therapies are the subject of enormous hype, endowed by the media with almost magical qualities and imagined by the public to bring about miracle cures. Stem cells have the potential to generate new cells of different types, and have been shown to do so in certain cases. Could stem cell transplants repair the damaged brain? In this book, neurobiologist Jack Price assesses the potential of stem cell therapies to treat such brain disorders as stroke, Alzheimer's disease, Parkinson's disease, and spinal cord injuries.Certainly brain disorders are in need of effective treatments. These disorders don't just kill, they disable, and conventional drug therapies have not had much success in treating them. Price explains that repairing the human brain is difficult, largely because of its structural, functional, and developme

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