Geriatric medicine Books

396 products


  • Geriatric Medicine at a Glance

    John Wiley and Sons Ltd Geriatric Medicine at a Glance

    1 in stock

    Book SynopsisGeriatric Medicine at a Glance logically presents the core principles of geriatric medicine, including mechanisms of ageing, changes in physiology commonly seen in older adults, and the clinical management and treatment of the key medical presentations affecting older patients.Table of ContentsList of Contributors vi Preface vii Acknowledgements viii How to use your revision guide ix Part 1 Core Concepts 1 1. Why is geriatric medicine different? 2 2. Population ageing 4 3. Theories of ageing 6 4. Physiology of ageing 8 5. Frailty 10 6. Comprehensive geriatric assessment 12 7. The international classification of functioning, disability and health 14 8. Physiotherapy 16 9. Occupational therapy 18 10. Assessment scales – physical function 20 11. Assessment scales – mental health 22 12. Ethical issues 24 Part 2 Common problems in older adults 26 13. Polypharmacy 28 14. Osteoporosis 30 15. Falls 32 16. Gait 34 17. Dizziness 36 18. Syncope 38 19. Urinary incontinence 40 20. Constipation 42 21. Delirium 44 22. Dementia 1: causes and classification 46 23. Dementia 2: assessment and management 48 24. Stroke 50 25. Parkinsonism 52 26. Nutrition 54 27. Pressure ulcers 56 Part 3 CGA in practice 58 28. Elder abuse 60 29. Surgical care 62 30. Geriatrics at the interface 64 31. Care homes 66 32. End-of-life care 68 MCQ questions 70 MCQ answers 78 References 80 Index 81

    1 in stock

    £27.50

  • The 36Hour Day

    Johns Hopkins University Press The 36Hour Day

    4 in stock

    Book SynopsisTable of ContentsForewordPreface1. Dementia2. Getting Medical Help for the Person Who Has Dementia3. Characteristic Behavioral Symptoms in People Who Have Dementia4. Problems in Independent Living5. Problems Arising in Daily Care6. Medical Problems7. Managing the Behavioral and Neuropsychiatric Symptoms of Dementia8. Symptoms Associated with Mood Change and Suspiciousness9. Special Arrangement If You Become Ill10. Getting Outside Help11. You and the Person Who Has Dementia12. How Caring for a Person Who Has Dementia Affects You13. Caring for Yourself14. Financial and Legal Issues15. Long-Term Care Arrangements16. Preventing and Delaying Cognitive Decline17. Brain Disorders and the Causes of Dementia18. Research in DementiaIndex

    4 in stock

    £16.50

  • The 36Hour Day

    Johns Hopkins University Press The 36Hour Day

    Out of stock

    Book SynopsisTable of ContentsForewordPreface1. Dementia2. Getting Medical Help for the Person Who Has Dementia3. Characteristic Behavioral Symptoms in People Who Have Dementia4. Problems in Independent Living5. Problems Arising in Daily Care6. Medical Problems7. Managing the Behavioral and Neuropsychiatric Symptoms of Dementia8. Symptoms Associated with Mood Change and Suspiciousness9. Special Arrangement If You Become Ill10. Getting Outside Help11. You and the Person Who Has Dementia12. How Caring for a Person Who Has Dementia Affects You13. Caring for Yourself14. Financial and Legal Issues15. Long-Term Care Arrangements16. Preventing and Delaying Cognitive Decline17. Brain Disorders and the Causes of Dementia18. Research in DementiaIndex

    Out of stock

    £19.47

  • Living Safely Aging Well

    Johns Hopkins University Press Living Safely Aging Well

    3 in stock

    Book SynopsisA chapter devoted to health literacy helps people and caregivers make the best use of the medical care system and a chapter on driving helps evaluate when it is no longer safe to be behind the wheel.Trade ReviewThis is a wonderful resource for anyone thinking about how to increase the safety of the home to allow for independence as people live longer. Publisher's Weekly I think anyone who's over the age of 50 needs this book on their shelf. If you're concerned about safety for a loved one or want to maintain independence yourself, Living Safely, Aging Well will give you the steps you need. -- Terri Schlichenmeyer Bookworm An excellent guide that describes the types of injuries that commonly happen at home, and how to prevent them... This is a top reference for any who would live well. Midwest Book ReviewTable of Contents1. What's "Old" Got to Do with It?2. Don't Fall!3. Too Hot and Too Cold4. Poisoning5. Preventing Asphyxia6. When Driving Is Dangerous7. The Backyard and the Workshop8. All around the House9. Seeing the DoctorAppendix A: Injury Statistics for People 65 and OlderAppendix B: Agencies and Organizationsthat Can HelpReferencesIndex

    3 in stock

    £16.62

  • Successful Aging as a Contemporary Obsession

    Rutgers University Press Successful Aging as a Contemporary Obsession

    15 in stock

    Book SynopsisExplores how the successful aging movement is playing out across five continents. Contributors investigate a variety of people to offer a fresh look at a major cultural and public health movement of our time, questioning what has become for many a taken-for-granted goalûaging in a way that almost denies aging itself.Trade Review"With public conversation about control of aging at an all-time high, these rich ethnographies from around the globe challenge stereotypes of success, failure, and ageism as they illustrate how vitality and vulnerability, independence, need, and care are resourcefully enacted. A timely corrective, this volume is essential for anyone interested in the diverse practices of interdependence and self-making in the world's ever-aging societies." -- Sharon R. Kaufman * author of Ordinary Medicine *"Lamb provides incisive deconstruction of modern notions of ‘successful aging,’ offering a wealth of theoretical perspectives on, and ethnographic illustrations of, approaches to aging in different cultural settings across the globe." -- Jeanne Shea * Department of Anthropology and Center on Aging, University of Vermont *"[A] valuable aspect of Successful Aging as a Contemporary Obsession is its global perspective....Lamb has done extensive fieldwork in West Bengal, where, far from being idealized, 'too much independence is commonly regarded as the worst thing that can befall one in old age.'" * This Chair Rocks *"The book offers insightful and sometimes highly emotional accounts of how we find meaning in the limits of our human condition, making it a delightful read regardless of one’s professional orientation." * Anthropology News *Table of ContentsPreface Acknowledgments Introduction: Successful Aging as a Twenty-first-Century Obsession Sarah Lamb, Jessica Robbins-Ruszkowski, and Anna Corwin Part I Gender, Sexuality, and the Allure of Anti-Aging 1 Successful Aging, Ageism, and the Maintenance of Age and Gender Relations Toni Calasanti and Neal King 2 Opting In or Opting Out? North American Women Share Strategies for Aging Successfully with (and without) Cosmetic Intervention Abigail T. Brooks 3 Aging Out: Ageism, Heterosexism, and Racism among Aging African American Lesbians and Gay Men Imani Woody 4 Erectile Dysfunction as Successful Aging in Mexico Emily Wentzell Part II Ideals of Independence, Interdependence, and Intimate Sociality in Later Life 5 Beyond Independence: Older Chicagoans Living Valued Lives Elana D. Buch 6 Growing Old with God: An Alternative Vision of Successful Aging among Catholic Nuns Anna I. Corwin 7 Aspiring to Activity: Universities of the Third Age, Gardening, and Other Forms of Living in Postsocialist Poland Jessica Robbins-Ruszkowski 8 Should Old Acquaintance Be Forgot? Friendship in the Face of Dementia Janelle S. Taylor Part III National Policies and Everyday Practices: Individual and Collective Projects of Aging Well 9 Getting Old and Keeping Going: The Motivation Technologies of Active Aging in Denmark Aske Juul Lassen and Astrid Pernille Jespersen 10 Foolish Vitality: Humor, Risk, and Success in Japan Jason Danely 11 Nurturing Life in Contemporary Beijing Judith Farquhar and Qicheng Zhang 12 Depreciating Age, Disintegrating Ties: On Being Old in a Century of Declining Elderhood in Kenya Janet McIntosh Part IV Medicine, Morality, and Self: Lessons from Life’s Ends 13 Successful Selves? Heroic Tales of Alzheimer’s Disease and Personhood in Brazil Annette Leibing 14 Comfortable Aging: Lessons for Living from Eighty-five and Beyond Meika Loe 15 Ageless Aging or Meaningful Decline? Aspirations of Aging and Dying in the United States and India Sarah Lamb Epilogue: Successful Aging and Desired Interdependence Susan Reynolds Whyte Notes on Contributors Index

    15 in stock

    £32.40

  • Oxford Handbook of Geriatric Medicine

    Oxford University Press Oxford Handbook of Geriatric Medicine

    2 in stock

    Book SynopsisThis new edition of the Oxford Handbook in Geriatric Medicine has been expanded and updated to reflect the substantial changes in clinical practice since the previous edition, including the Francis report and the impact on care for the older patient, the National Dementia Strategy and screening, and the evolution of the role of Geriatricians in other specialities. It includes new material on risk scoring management of TIA, and a new chapter on the older surgical patient. With an ageing population, geriatric medicine is increasingly central to emergency and internal medicine in hospital settings and in general practice. Diseases are more common in the older person, and can be particularly difficult to assess and to treat effectively in a field that has limited evidence, yet makes up a substantial proportion of the work of most clinicians. Using clinical vignettes and how-to boxes to provide practical advice on common problems, this is a practical, accessible, and essential handbook for all medical staff who manage older patients.Trade ReviewThe book gives a very good overview of the main and most common areas of elderly care ... it has a really good, user-friendly layout and covers a wide range of conditions in a simplified way. * BMA reviewing panel, BMA Medical Book Awards 2019 *... Packed with clinical tips and case examples to help put knowledge into practice, [...] this comprehensive handbook is well worth the investment and lends itself to being used in day-to-day clinical practice. * A Illsley, British Journal of Hospital Medicine *This is an excellent book. It is succinct yet easy to read ... there are useful little boxes of 'How To's e.g. How To Give Sub-Cut Fluids, Use Digoxin, Assess Depression etc. I thought I know how to do many of these tips but I still found then useful and interesting. This is a useful book for anyone spending time looking after old patients. * BMA Medical Book Competition (from a review of the previous edition) *This is a thoughtful and challenging book that is very serious reading for clinicians who frequently encounter elderly patients in their practice. * Doody's Notes, Dec 2012 *All physicians who treat older people must have geriatric expertise. It goes without saying that internists, hospital doctors and GPs need easy access to geriatric knowledge, but also surgeons, neurologists, rheumatologists, and other specialists who encounter older patients should know something about the special challenges regarding elderly health and disease, clinical, ethical and practical. The target group is therefore most hospital doctors and all general practitioners sturdy, handheld book like this - along with the online encyclopedia - provides flexible and customized access to the knowledge, advice and guidance. * Tidsskrift for Den norske legeforening, Feb 2013 *...this is a brilliantly crafted book and a wonderful contribution to the field. * Doody's Notes (from a review of the previous edition) *Table of Contents1: Ageing 2: Organizing geriatric services 3: Clinical assessment of older people 4: Rehabilitation 5: Falls and funny turns 6: Drugs 7: Neurology 8: Stroke 9: Psychiatry 10: Cardiovascular 11: Chest medicine 12: Gastroenterology 13: Renal medicine 14: Homeostasis 15: Endocrinology 16: Haematology 17: Musculoskeletal system 18: Pressure injuries 19: Genitourinary medicine 20: Incontinence 21: Ears 22: Eyes 23: Skin 24: Infection and immunity 25: Malignancy 26: Death and dying 27: Ethics 28: Finances 29: Peri-operative Medicine

    2 in stock

    £36.09

  • Breakfast with the Centenarians: The Art of

    Atlantic Books Breakfast with the Centenarians: The Art of

    5 in stock

    Book SynopsisLearn the art of growing old from the supercentenarians living life to the fullest.It's said that life begins at 40 - but that number is constantly revised upwards as we live longer and longer. With the number of centenarians having quadrupled in the last thirty years, more of us can now hope to reach the 100-year mark than ever before. But how can we navigate this journey with grace, dignity and style? In this charming and informative book, Daniela Mari - the Italian doctor caring for some of the oldest people on the planet - draws on her experiences as a renowned gerontologist to reveal the science behind a healthy, happy old age. It turns out that the world's centenarians can teach us a thing or two about ageing well. And the secrets are not always what you'd think. Informed by the latest medical studies and incredible stories of individual longevity, Mari shows how our lifestyles can far surpass the influence of our genetics and why a daily glass of liquor isn't the end of the world. From our sleeping habits and diet to the crucial importance of our passions and interests, Breakfast with the Centenarians is the essential handbook for a fruitful and fulfilling old age.

    5 in stock

    £10.44

  • Pflege mini Psychopharmaka im Alter

    Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Pflege mini Psychopharmaka im Alter

    15 in stock

    Book SynopsisEin praktisches Taschenbuch zum schnellen Nachschlagen für Pflegefachkräfte in stationären und ambulanten Pflegeeinrichtungen. Für einen verantwortungsvollen und bewussten Umgang mit Psychopharmaka in der Betreuung älterer Menschen.Hier finden Pflegende die wichtigsten Fakten zur Psychopharmakotherapie: - Wirkung und Nebenwirkungen verschiedener Medikamentengruppen- Wechselwirkungen mit anderen Medikamenten- Medikamentenprofile nach Handelsnamen und Wirkstoffen in alphabetischer Reihenfolge Dieses Wissen befähigt Pflegekräfte in der Kommunikation mit dem Arzt: über negative Wechselwirkungen und Folgeerscheinungen, z.B. z.B. Desorientierung, erhöhte Sturzgefahr, Immobilität, einer eingestellten Medikation zu informieren. Auch informiert die erfahrene Autorin über alternative Angebote z.B. der Basalen Stimulation, Seelsorge, Physiotherapie, Ergotherapie, Aromatherapie.Table of ContentsUmgang mit Medikamenten.- Antidementiva.- Antidepressiva.- Schlaf- und Beruhigungsmittel.- Antipsychotika.- Besondere Probleme älterer Menschen.- Alternativen.- Anhang.- Literatur.

    15 in stock

    £13.38

  • Healthy Aging An Issue of Clinics in Geriatric Medicine

    Elsevier Health Sciences Healthy Aging An Issue of Clinics in Geriatric Medicine

    1 in stock

    1 in stock

    £66.59

  • Alzheimers Disease and Infectious Causes

    McFarland & Co Inc Alzheimers Disease and Infectious Causes

    Out of stock

    Book Synopsis With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer''s disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer''s disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer''s patients. Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer''s disease. Sources of infection in Alzheimer''s disease vary from childhood infections to gut microbes that find their way into the brain as a result of aging, leaky gut syndrome, and increased permeability of the blood brain barrier. Studies and ongoing clinical trials show that treatment of viral and bacterial infections, as well as restoring a healthy balance to Trade Review[Moore's] writing is informed by her knowledge of medical literature, but her accessible prose allows any interested patient or caregiver to understand recent advances in various topics. [She] starts with basic information about Alzheimer's disease, and includes accessible data on genetic and environmental risk factors implicated in research, but the focus is on infectious causes...excellent." —Library JournalTable of Contents Table of Contents Acknowledgments vi Preface 1 Introduction 3 One—The Mystery of the Mind and Consciousness 7 Two—Infection as a Primary Cause 32 Three—Microorganisms and the Microbiome 48 Four—The Immune System, Neurodegeneration and the Blood-Brain Barrier 71 Five—Stages and Pathology of the Disease 86 Six—Herpes Viruses 105 Seven—Other Associated Viruses and the Prion Connection 119 Eight—Bacterial Infections 130 Nine—Fungal and Protozoan Infections 144 Ten—Risk Factors 153 Eleven—Genetic Influences 170 Twelve—Risk Reduction and Therapies 184 Bibliography 203 Index 215

    Out of stock

    £20.89

  • Elderhood: Redefining Aging, Transforming

    Bloomsbury Publishing USA Elderhood: Redefining Aging, Transforming

    15 in stock

    Book Synopsis

    15 in stock

    £16.00

  • Creative Care A Revolutionary Approach to

    HarperCollins Publishers Inc Creative Care A Revolutionary Approach to

    10 in stock

    Book SynopsisTrade Review“Creative Care is a love letter to aging. Not a prescription filled with should, it’s a beautifully rendered invitation to be curious and flexible, meeting elders wherever they happen to be in the moment and making that moment richer, sweeter, and more meaningful for all.” — Cynthia Orange, author of Take Good Care and Shock Waves "Moving, honest, and timely, Creative Care’s inspiring stories will comfort families struggling with dementia across the world." — Diane E. Meier MD, director of the Center to Advance Palliative Care and MacArthur Fellow "Basting brings hope and meaning to millions of families living in the shadow of Alzheimer's disease. A powerful book of healing." — R. Sean Morrison, MD, chair of the Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai “Alzheimer's is devastating because it doesn't only affect the person suffering from the disease. In the face of this challenge the response from the academic and policy side has been feeble. For the first time, this book gives people hope and powerful ways to deal with its challenges.” — Dean Sherzai, MD, PhD, author of The Alzheimer’s Solution "Invites us to shift focus from how well we remember the past to how well we inhabit the present--for ourselves and with others. Basting reveals the power of creativity to expand our humanity and enrich the time we have." — Marie-Therese Connolly, MacArthur Fellow and senior scholar at The Wilson Center “Upends the bleak ideas of caregiving and dementia as a disease that robs us of our humanity. Basting shows otherwise. Together–caregiver and person with dementia–can create something meaningful. Caregivers will value this; it ought to be required reading for all clinicians and policymakers.” — Jason Karlawish, MD, co-director of the Penn Memory Center, University of Pennsylvania and author of The Disease of the Century “Creative Care brims with essential wisdom that may forever change the way we care for one another. In these pages Basting gives readers the most precious gift of all: hope.” — Dave Isay, founder of StoryCorps "As an artist and scholar, Basting has infused art into dementia and elder care, leveraging song, dance, improvisation, and theater to elicit communication and joy. Her ideas have spread to care centers across the country and individual families hoping to forge meaningful connections with loved ones." — Psychology Today

    10 in stock

    £19.00

  • PersonCentered Communication with Older Adults

    Elsevier Science PersonCentered Communication with Older Adults

    Out of stock

    Book SynopsisTable of ContentsChapter 1 - Providers, Older Adults, and Communication Chapter 2 - How to Learn and Implement the Person-Centered Approach to Communication Chapter 3 - The Professional Relationship: The Foundation of Person-Centered Communication Chapter 4 - Nuts and Bolts of Interpersonal Communication: The Clinical Face of Service Chapter 5 - Person-Centered Communication: Ageism-The Core Problem communication Chapter 6 - Person-Centered Communication: Age-Related Changes, Cultural Challenges, and Difficult Conversations Chapter 7 - Person-Centered Communication and Stress: The Eighth "C" - Calmness Chapter 8 - Person-Centered Communication: Mental Imagery and Imagined Interactions Chapter 9 - Neurocardiology of Communication: The Ninth "C"—Coherence Chapter 10 - The Physics of Interpersonal Communication: The Tenth "C"—Connection Chapter 11 - Person-Centered Interpersonal Communications: The Future of Aging

    Out of stock

    £49.58

  • Handbook of Mental Health and Aging

    Elsevier Science Handbook of Mental Health and Aging

    15 in stock

    Table of ContentsList of Contributors Preface 1. Concepts and Issues in Mental Health and Aging Nathan Hantke and Ruth O'Hara 2. Epidemiology of Selected Mental Disorders in Later Life Brenna N. Renn, Patricia A. Arean and Jurgen Unutzer 3. Culture and Ethnicity in the Mental Health of Older Adults Lucas Torres, Claire Bird and Felicia Mata-Greve 4. Stress, Mental Health, and Aging Raeanne C. Moore, Elizabeth Straus and Laura M. Campbell 5. Structural Changes in the Aging Brain Meghan Riddle and Warren D. Taylor 6. Sleep-Dependent Cellular Chemical Changes in the Aging Brain Gordon X. Wang and Philippe Mourrain 7. Biomarkers of Cognitive Impairment in Late-Life Depression Breno S. Diniz and Meryl A. Butters 8. Accelerated Brain Molecular Aging in Depression Rammohan Shukla and Etienne Sibille 9. Cognitive Dysfunction in Late-Life Psychiatric Disorders: Phenotypes, Risk Factors, and Treatment Targets Christina F. Chick, Casey Buck and Ruth O'Hara 10. Suicide in Late Life Joshua T. Jordan and Lauren A. Anker 11. Anxiety and its Disorders in Old Age Sherry A. Beaudreau, Christine E. Gould, Susan Sharp Kolderup and Nehjla Mashal 12. Bipolar Disorders in Older Adults Laura Hein, Annemiek Dols and Lisa T. Eyler 13. Positive Psychiatry and Successful Aging in People with Schizophrenia Dilip V. Jeste, Ryan Van Patten and Ellen E. Lee 14. Alzheimer's Disease and Other Neurocognitive Disorders Lucy Y. Wang, Beth Ann LaBardi, Murray A Raskind and Elaine R Peskind 15. Substance Use Disorders in the Elderly Tylor J. Jilk and Martin S. Mumenthaler 16. Sleep Disorders and Aging Logan Schneider, Rosy Karna, Makoto Kawai and Kai Parker-Fong 17. Aging of Persons with Neurodevelopmental Disabilities Lauren A. Anker, Christina F. Chick and Joachim F. Hallmayer 18. Bereavement and Grief Danielle K. Florioso, Alana Iglewicz and Sidney Zisook 19. Neuropsychology with Older Adults Nathan Hantke and Nicholas T. Bott 20. Integrative Precision-Medicine Approach to Cognitive Assessment in Older Adults Sharon Naparstek, Omer Linkovski and Limor Gertner 21. Functional Assessment in Geriatric Mental Health Adriana Seelye, Sarah Brown, Katherine Dorociak, Jeffrey Kaye, Katherine Wild and Snezana Urosevic 22. Psychotherapeutic Interventions with Older Adults: Now and Into the Future Leander K. Mitchell and Nancy A. Pachana 23. Psycopharmacologic Treatment Vimal M. Aga, Mujeeb U. Shad, Hongru Zhu and Carl Salzman 24. Technology-Based Mental Health Assessment and Intervention Christine E. Gould, Flora Ma, Julia R. Loup, Christine Juang, Erin Y. Sakai and Renee Pepin 25. Community and Home Care for Mentally Ill Older Adults Erin Cassidy-Eagle 26. Forensic and Ethical Issues Mousa S. Botros, Julie E. Guzzardi, Regina M. Carney, Spencer Eth and Gregory B. Leong 27. The Economics of Geriatric Mental Health Care Nicholas T. Bott 28. The Future of Mental Health and Aging Nathan Hantke, Ruth O'Hara, Sherry A. Beaudreau and Amit Etkin Author Index Subject Index

    15 in stock

    £101.15

  • Geriatric Neurology

    Elsevier Science Publishing Co Inc Geriatric Neurology

    Book SynopsisTable of ContentsSection I. Foundations and Principles of Geriatric Neurology 1. Geriatric pharmacotherapy: Appraising new drugs for neurological disorders in older patients 2. Animal models of cognitive aging and circuit-specific vulnerability 3. Psychopharmacology and pharmacokinetics 4. Models of care 5. Neurologic examination in the elderly 6. Cognitive and neuropsychological evaluation of the elderly 7. Chronic neurological disorders and related comorbidities: Role of age-associated physiological changes 8. Autonomic dysfunction: diagnosis and management 9. Epidemiology of aging and associated neurological disorders: Prevalence and incidence of Alzheimer disease and other dementias 10. Neuropsychology of aging 11. Cognitive reserve 12. Neuroimaging in aging and neurological diseases Section II. Neurological Disorders of Late-Life 13. Alzheimer disease 14. Parkinson disease – diagnosis and appreciation of comorbidities 15. Frontotemporal dementia 16. Recognizing and treating atypical Parkinson disorders 17. Down syndrome 18. The long-term consequences of repetitive head impacts: Chronic traumatic encephalopathy 19. Delirium in the critically ill patient 20. Vascular cognitive impairment: a preventable component of dementia 21. Stroke in the elderly 22. Gait and dementia 23. Assessment and treatment of major depression in older adults 24. Neuropsychiatric symptoms in dementia 25. Epilepsy and aging 26. Sleep physiology and disorders in aging and dementia Section III. General Topics in Geriatric Neurology 27. Urological function and dysfunction in aging: Diagnosis and treatment 28. Geriatric rehabilitation 29. Palliative medicine and end-of-life care 30. Headache in the elderly 31. Driving in the elderly in health and disease 32. The evolution of geriatric neurology

    £187.00

  • Integrative Geriatric Medicine

    Oxford University Press Inc Integrative Geriatric Medicine

    Out of stock

    Book SynopsisIntegrative geriatrics is a new field of medicine that advocates for a whole-person, patient-centered, primarily non-pharmacological approach to medical care of the elderly. Most current geriatric practices overprescribe medications and procedures and underutilize non-pharmacological, low-cost, high-touch methods. Patients, however, often show reluctance towards these standard practices, as the interventions they rely upon are often invasive. The practice of integrative geriatrics is rooted in lifestyle interventions, such as nutrition, movement therapies, and mind-body and spirituality approaches, that allow patients to have different path to their healthcare-one that utilizes pharmaceuticals and invasive procedures only when safer integrative approaches are not available or not effective.This first definitive textbook of this new field presents detailed, evidence-based information for all healthcare providers and advocates who work with the geriatric population. It is intended not only for providers in outpatient settings, but also for those who work in nursing homes, assisted and independent living facilities, and senior community centers. In addition, Integrative Geriatric Medicine will provide valuable information for leaders and politicians who are involved with implementing policies and procedures for care of elderly patients looking for safer, less costly, and more patient-centered approaches.Trade ReviewIntegrative Geriatric Medicine provides a critical understanding of the current evidence base and application of integrative approaches to elder care. It is a fitting member of Dr. Weil's Integrative book series, and a valuable source of information to be referenced time and time again. * Erika Rogan, Journal of Applied Gerontology *Table of Contents1: Mikhail Kogan and Kyle Meehan: Introduction 2: Julie Wendt, Anna Rotkiewicz, and Alice Berg: Geriatric Nutrition 3: Joseph P. Cleaver, Alice Schmidt Kehaya, and Mikhael Kogan: Exercise, Frailty and Functional Reserve: Concepts and Optimization 4: Ronak Mehta, Mariatu Koroma-Nelson, Elizabeth Mackenzie , and Birgit Rakel: Preventative Geriatrics 5: Angela Gabriel and Tiffany C. Hoyt: Acupuncture and Traditional Chinese Medicine (TCM) 6: Maryclaire O'Neill, Eric J. Roseen, Mary Starich, Anne McDonald, Yael Flusberg, and Aaron A. Davis: Manual and Movement Therapies 7: Luann Jacobs, Mary Kendell, and Yael Flushberg: Energy Modalities and Aromatherapy 8: Deirdre Orceyre and Meredith Bull: Naturopathic Medicine 9: Christina M. Puchalski and Patricia A. Bloom: Spirituality and Mind-Body Medicine in Geriatrics 10: George Muñoz and Mikhail Kogan: Men's Health 11: Mary Kendell and Margie Wentzel: Women's Health 12: Marc Brodsky and Ann E. Hasen: Pain 13: Mara Caroline, Ryan Bradley, and Mimi Guarneri: Cardiovascular Disease 14: James Yang: Endocrine disorders: Integrative treatments of hypothyroidism, diabetes, and adrenal dysfunction 15: Angela J. Shepherd and Juliet M. McKee: Integrative Osteoporosis 16: Victor Sierpina, Karen Welch, Dimple Desai, and Anna Rotkiewicz: The Healthy Gut in Older Adults 17: Christina Prather, Mariatu Koroma-Nelson, and Mikhail Kogan: Common Geriatric Infections 18: Seema Rao: Integrated Approaches to Treating Lung Diseases in the Geriatric Population 19: Ronald Glick, Marie Anne Gebara, and Eric Lenze: Integrative Geriatric Psychiatry 20: Aviva Ellenstein, Christina Prather, and Mikhail Kogan: Neurodegenerative Diseases: Parkinson's and Alzheimer's Diseases 21: Amy Littlefield, Deirdre Orceyre, and Stephanie Cheng: Integrative Oncology 22: Nisha Manek and George Muñoz: Common Rheumatic Diseases in the Elderly 23: Anca Dinescu and Mikhail Kogan: Falls 24: Ilana Seidel and Justin Sevier: Skin, Vision, and Hearing 25: Deirdre Orceyre, Ronak Mehta, and Mikhail Kogan: Functional Laboratory Studies 26: Robert L. Jayes and Robert M. Kaiser: Primary Care for Homebound Patients 27: Elizabeth L. Cobbs, Amanda Hull, and Alyssa Adams: Person-Directed Health Care across the Life Span: The Veterans Affairs Health Care System 28: Tahira I. Lodhi and Tania Alchalabi: Long-Term Residential Care 29: Beverly Lundsford and Terry A. Mikovich: Inter-Disciplinary Team-based Care 30: Katalin Roth: Bioethical Issues in Integrative Geriatrics 31: Angela Lee, Stephanie Cheng, and Dale Lupu: Integrative Palliative Care 32: Michelle Sierpina and Beverly Lunsford: Positive Aging

    Out of stock

    £103.79

  • The REACH OUT Caregiver Support Program A Skills

    Oxford University Press Inc The REACH OUT Caregiver Support Program A Skills

    Out of stock

    Book SynopsisThe REACH OUT Caregiver Support Program offers a multi-component, tailored, and flexible intervention for caregivers of people with dementia that is focused on the evidence-based therapeutic strategy of problem solving.Trade ReviewA unique and detailed blueprint for using the evidence-based REACH intervention. Includes a caregiver risk appraisal, flexible and detailed scripts, assessments, and handouts, tailored to and proven effective in the frontlines of care. An essential resource for professionals and students working with dementia family caregivers. Will be required reading in my courses." * William E. Haley, PhD, University of South Florida *Absolutely essential! This REACH OUT guide offers 'must-use' practical resources for clinicians working in community and primary care settings. These strategies truly represent the best of science and practice for addressing the complex needs of informal dementia care providers." * Ann M. Steffen, PhD, ABPP, University of Missouri-St. Louis. Author of Treating Later-Life Depression, Second Edition *Table of ContentsChapter 1: Development And Overview Chapter 2: Risk Appraisal And Action Plans Chapter 3: Risk Area 1: Home Safety Chapter 4: Risk Area 2: Keeping The Caregiver Physically Healthy Chapter 5: Risk Area 3: Caregiver Emotional Well-Being Chapter 6: Risk Area 4: Managing Challenging Behaviors Chapter 7: Risk Area 5: Social Support Chapter 8: Filling In The Gaps APPENDICES Appendix A: Caregiver Notebook Appendix B: Generic Problem-Solving Form: Action Plan Template Appendix C: Sample Challenging Behavior Action Plans Appendix D: REACH OUT Home Safety Checklist Appendix E: Healthy Lifestyle Guide Appendix F: REACH OUT Pleasant Events Summary Form Appendix G: ABCs of Challenging Behaviors Appendix H: Supplemental Material for Deciding Risk Priority Appendix I: Adverse Events Appendix J: REACH OUT Clinician Treatment Implementation and Tracking Checklists

    Out of stock

    £50.72

  • Growing Old in America

    Oxford University Press Growing Old in America

    15 in stock

    Book SynopsisA history of aging in America surveys and compares actualities and attitudes in the eighteenth, nineteenth, and twentieth centuries and suggests practical improvements on the current inadequate system of pensions, social security, medicare, and other programs.Trade Review"The only major interpretive study of a very important and, needless to say, timely subject...deserves a wide audience, not only among historians, but among members of the helping professions and all others concerned with the welfare of our senior citizens."--Journal of American History

    15 in stock

    £14.24

  • The Osteoporosis Book A Guide for Patients and Their Families

    Oxford University Press The Osteoporosis Book A Guide for Patients and Their Families

    15 in stock

    Book SynopsisOsteoporosis currently affects 25 million people in the United States, and as the baby boomers enter their fifties, the disease is poised to strike millions more. In this text, readers will find everything they need to know to slow, stop, and even reverse the bone loss that causes osteoporosis.Trade Review"This comprehensive book was written as a guide for patients and their families and, as such, covers a variety of topics related to osteoporosis in a simple, well-explained way....This is an excellent reference."--Physiotherapy Canada"Although much more widespread among women, osteoporosis also strikes men, so this overview of the disease speaks to a larger audience than many may suspect. Lane uses her experience as a clinician to add greatly to the book, notably in the case histories she cites and the understanding of patients she expresses."--Booklist"A concise, authoritative overview of this major health problem largely affecting women.... Lane makes effective use of case studies throughout the text to illustrate typical risk situations and treatment options. Recommended for both public and academic libraries for the more sophisticated consumer."--Library Journal"The Osteoporosis Book by osteoporosis researcher Nancy E. Lane, M.D., codirector of rheumatology at San Francisco General Hospital, covers all bases: a description of the disease and its causes, who is at risk, diagnosis, prevention, treatment and dealing with its pain and problems."--Consumers Digest

    15 in stock

    £19.79

  • A Means to an End

    Oxford University Press, USA A Means to an End

    15 in stock

    Book SynopsisWhy do we age? Is aging inevitable? Will advances in medical knowledge allow us to extend the human lifespan beyond its present limits? Because growing old has long been the one irreducible reality of human existence, these intriguing questions arise more often in the context of science fiction than science fact. But recent discoveries in the fields of cell biology and molecular genetics are seriously challenging the assumption that human lifespans are beyond our control. With such discoveries in mind, noted cell biologist William R. Clark clearly and skillfully describes how senescence begins at the level of individual cells and how cellular replication may be bound up with aging of the entire organism. He explores the evolutionary origin and function of aging, the cellular connections between aging and cancer, the parallels between cellular senescence and Alzheimer''s disease, and the insights gained through studying human genetic disorders--such as Werner''s syndrome--that mimic theTrade Review"Clark effortlessly takes readers from the simple to the complex, from a discussion of single-celled organisms to human beings.... He also does a nice job of exploring the causes of Alzheimer's disease, various forms of cancer and an array of genetic disorders that afflict the young by making them age prematurely.... Neatly informative."--Publishers Weekly"Why in spite of healthy, well-fed, well-watered lives do people age and die? The well-informed physician-researcher, William R. Clark, excitedly reveals new studies of progeric and normal mammals as he tracks the inevitable corollary to human life: the inexorable rhythmic march to human death."--Lynn Margulis, Distinguished University Professor, Department of Geosciences, University of Massachusetts, Amherst and co-author of What is Life" and What is Sex""Fascinating and informative.... One of the book's most engaging elements is Clark's ability to show how scientists think about problems and approaches in the field."--BooklistTable of ContentsINTRODUCTION ; 1. Aging, Senescence, and Lifespan ; 2. The Nature of Cellular Senescence and Death ; 3. The Evolution of Senescence and Death ; 4. Of Embryos and Worms and Very Old Men: The Developmental Genetics of Senescence and Lifespan ; 5. Human Genetic Diseases that Mimic the Aging Process ; 6. Cycling to Senescence ; 7. Replicative Immortality: Cancer and Aging ; 8. Caloric Restriction and Maximum Lifespan ; 9. With Every Breath We Take: Oxidative Stress and Cellular Senescence ; 10. The Aging Brain ; 11. A Conditional Benefit

    15 in stock

    £24.74

  • Psychiatry in LongTerm Care

    Oxford University Press Psychiatry in LongTerm Care

    15 in stock

    Book SynopsisAs the baby boom generation ages, the number of people requiring long-term care will grow dramatically in developed nations. A majority of them will become increasingly frail and suffer from dementia and associated neuropsychiatric symptoms. Against this backdrop, Psychiatry in Long-Term Care, Second Edition (first published under the title Psychiatric Care in the Nursing Home) comprehensively reviews the present state of knowledge on how to identify the major psychiatric disorders affecting residents of long-term care facilities and how to intervene. Edited and written by some of the world''s foremost authorities, the book provides in-depth coverage of topics such as these: - General approaches to assessment and treatment of behavioral disturbances - Depression - Anxiety - Dementia - Sleep impairment - Psychosis - Substance use disorders - Contemporary strategies for successful psychopharmacological and psychotherapeutic interventions Complementing these chapters with clinical guideTable of ContentsSection One: Psychiatric Disorders 1: Epidemiology of Psychiatric Conditions in Nursing Homes, Ann L. Gruber-Baldini, Hannah Day, and Jay Magaziner 2: Dementia in Nursing Home Patients: Assessment and Management, Solasinee Hemrungrojn and Jeffrey L. Cummings 3: Delirium in the Nursing Home Setting, Steven F. Huege and Joel E. Streim 4: Mood Disorders, Ashok J. Bharucha and Soo Borson 5: Anxiety Disorders, Art Walaszek and Timothy Howell 6: Schizophrenia and Other Psychotic Disorders, Gauri N. Savla, Jody DelaPena-Murphy, Daniel D. Sewell, Daniel S. Kim, and Dilip V. Jeste 7: Sleep-Wake Disorders in Long-Term Care Facility Residents, Yohannes Endeshaw 8: Sexual Disorders, Peggy A. Szwabo 9: Personality Disorders, Marc E. Agronin 10: Mental Retardation, C. Michael Henderson 11: Substance Use Disorders, Kenneth Schwartz Section 2: Psychiatric Interventions 12: General Approaches to Behavioral Disturbances, Lisa L. Boyle, Anton P. Porsteinsson, and Pierre N. Tariot 13: Principles of Geriatric Psychopharmacology, Adrian Leibovici and Laurie Daiello 14: Insight-Oriented, Interpersonal and Integrative Psychotherapy, Richard A. Zweig, Patricia Marino, and Gregory A. Hinrichsen 15: Cognitive and Behavioral Therapy, Lurgis Karuza and Paul Katz 16: Family Interventions, Lee Hyer, Shailaja Shah, and Amanda Sacks 17: Environmental and Milieu Interventions, Jiska Cohen-Mansfield and Rene Laje 18: Staff Education in Long-term Care Facilities, David K. Conn and Joy Richards 19: Psychiatric Consultation and Liaison, Gary S. Moak Section 3: Societal Influences 20: An Overview of Residents, Care Providers and Regulation of Medical Practice in the Long-Term Care Continuum, Suzanne Gillespie and Paul R. Katz 21: Ethical and Medicolegal Issues, Marshall B. Kapp 22: Mental Health in the Assisted Living Setting Quincy M. Samus and Adam Rosenblatt Index

    15 in stock

    £66.00

  • Coping with Aging

    Oxford University Press, USA Coping with Aging

    15 in stock

    Book SynopsisCoping with Aging is the final project of the late Richard S. Lazarus, the man whose landmark book Emotion and Adaptation put the study of emotion in play in the field of psychology. In this volume, Lazarus examines the experience of aging from the standpoint of the individual, rather than as merely a collection of statistics and charts. This technique is in line with his long-standing belief that experiences should be looked at in their specific contexts, rather than squeezed into an overly general statistical viewpoint that loses the subjects'' motivations. Drawing on his five decades of pioneering research, Lazarus looks aging, emotion, and coping, and stability and change in both environment and personality. Because Lazarus mixes academic rigor with everyday examples, this volume will be both useful to scholars and accessible to the lay audience that has so much gain from a systematic understanding of aging and emotion.Trade Review"...may mark a breakthrough of sorts in this area...this book enlightens, engages, and outlines very clearly and concisely what aging is like, what problems we will have as we all age, and what we can possibly do to confront the massive challenges of aging head-on and cope as best as we can. I dare say that this book should be recommended reading for those of us who think about the daily process of aging."--PsycCRITIQUES "...may mark a breakthrough of sorts in this area...this book enlightens, engages, and outlines very clearly and concisely what aging is like, what problems we will have as we all age, and what we can possibly do to confront the massive challenges of aging head-on and cope as best as we can. I dare say that this book should be recommended reading for those of us who think about the daily process of aging."--PsycCRITIQUESTable of ContentsPREFACE ; PART I: INSPIRATION AND OVERVIEW ; INTRODUCTION: AGING, ONCE OVER LIGHTLY ; PART II: THEORETICAL FRAMEWORK ; PART III: STABILITY AND CHANGE ; PART IV: CENTRAL EXPERIENCES OF AGING: CASE HISTORIES ; PART V: PRACTICAL APPLICATIONS ; REFERENCES

    15 in stock

    £44.09

  • Geriatric Palliative Care

    Oxford University Press Inc Geriatric Palliative Care

    15 in stock

    Book SynopsisThe growing geriatric population in the United States has created an increasing need for palliative medicine services across the range of medical and surgical specialties. Yet, palliative medicine lacks the resources to carry such a workload itself. Geriatric Palliative Care addresses this need by encouraging individual specialties to own the management of elderly with the same vigor as they own other key management competencies within their specialty. This clinically focused and highly practical handbook, which compliments the more comprehensive text Geriatric Palliative Care by Sean Morrison and Diane Meier (Oxford University Press, 2003), encourages this process of learning and ownership across many medical specialties. Designed to be readable and easily accessible to a range of health care providers, Geriatric Palliative Care outlines specific strategies for caring for specific palliative care issues common in elderly patients. The handbook also provides evidence based advice for hTrade ReviewAny member of the health care team who is engaging with geriatric patients in need of palliative care would benefit from having this guide on the bookshelf. * R. Kevin Mallinson, Oxford University Press Journals: Gerontologist *This is a well-written, easy-to-read book. It covers many topics at a very basic level, making it an exceptional reference for students, trainees, and generalists. There are many other books specific to palliative care and to geriatrics, but none that blend the two. * Doody's Notes *I think this book provides a good coverage and it is very practical and useable. Given that we are encountering an increasing number of older adults in palliative care, this would be a useful book to have on the shelf for quick day-to-day reference, providing the geriatric perspective on the problems we encounter... Palliative Care Book of the Month * IAHPC Newsletter *Table of ContentsSection 1: Overview ; 1. Introduction to Geriatric Palliative Care ; 2. Principles of Care ; 3. Medication Management ; 4. Introduction to Caregiving ; 5. Financing Palliative Care and Hospice ; 6. Ethical Decision-Making ; 7. Prognostication ; 8. Advance Care Planning ; 9. Communication Skills ; 10. Managing Conflict ; 11. Care Transitions ; 12. The Hospice Model of Palliative Care ; 13. Insurance ; Section 2: Special Issues in Geriatric Palliative Care ; 14. Palliative Care Emergencies ; 15. Dying at Home ; 16. Cultural Considerations ; 17. Complementary and Alternative Therapies ; 18. Clinician Self Care ; 19. Last Hours of Living ; 20. Bereavement ; 21. Spirituality ; 22. Palliative Sedation ; 23. Requests for Hastened Death ; 24. Assistive Aids and Devices ; 25. Rehabilitation ; 26. Mechanical Ventilation ; 27. Artificial Nutrition and Hydration ; Section 3: Caregivers ; 28. Caregiving ; Section 4: Symptoms ; 29. Pain Management ; 30. Fatigue ; 31. Failure to Thrive ; 32. Sweating and Fever ; 33. Behavioral Disorders in Dementia ; 34. Delirium ; 35. Terminal Delirium ; 36. Sleep Disorders ; 37. Dizziness ; 38. Headache ; 39. Myoclonus ; 40. Cough and Secretion ; 41. Dyspnea ; 42. Anorexia and Cachexia ; 43. Ascites ; 44. Bowel Obstruction ; 45. Constipation ; 46. Diarrhea and Fecal Incontinence ; 47. Mucositis ; 48. Dyspepsia ; 49. Dysphagia ; 50. Encephalopathy ; 51. Gastroparesis ; 52. Hiccups ; 53. Nausea and Vomiting ; 54. Urinary Retention ; 55. Urinary Incontinence ; 56. Bleeding ; 57. Thromboses ; 58. Lymphoedema ; 59. Pressure Ulcers ; 60. Pruritus ; 61. Malodorous Wounds ; Section 5: Diseases and Syndromes ; 62. Frailty ; 63. Falls ; 64. Depression ; 65. Anxiety ; 66. Alcohol Abuse and Dependence ; 67. Dementia ; 68. Seizure ; 69. Stroke ; 70. Parkinson Disease and Essential Tremor ; 71. Malignant Spinal Cord Compression ; 72. End Stage Lung Disease ; 73. Aspiration Pneumonia ; 74. Diverticulitis ; 75. Mesentric Ischemia ; 76. End Stage Liver Disease ; 77. Feeding Tube Management ; 78. End Stage Renal Disease ; 79. Recurrent Urinary Tract Infection ; 80. Diabetic Management in Advanced Illness ; 81. End Stage Heart Disease ; 82. Arrhythmias ; 83. Valvular Heart Disease ; 84. Peripheral Arterial Disease ; 85. Hip Fracture Management ; 86. Osteoarthritis ; 87. Lumbar Spinal Stenosis ; 88. Osteoporotic Fracture ; 89. Polymyalgia Rheumatica ; 90. Rheumatoid Arthritis ; 91. Osteomyelitis ; 92. Herpes Zoster ; 93. HIV-AIDS ; 94. Skin Cancers ; 95. Colorectal Cancer ; 96. Head and Neck Cancer ; 97. Breast Cancer ; 98. Prostate Cancer ; 99. Lung Cancer ; 100. Leukemia ; 101. Lymphoma ; 102. Intracranial Malignancies ; Section 6: The Interdisciplinary Team ; 103. Clinical Psychologist ; 104. Complementary and Alternative Practitioners ; 105. Dietician ; 106. Massage Therapist ; 107. Music Therapist ; 108. Registered Nurse ; 109. Physical Therapist ; 110. Pharmacist ; 111. Physician ; 112. Social ; 113. Speech and Language Pathologist ; 114. Chaplain

    15 in stock

    £91.38

  • Dementia

    Oxford University Press Inc Dementia

    Book SynopsisAdults 65 and older are the fastest growing segment of the population worldwide, which means there will be more people living with mild cognitive impairment and dementia. Written at a resident level, the Primer on Dementia provides early career professionals with the information necessary to care for the often complex clinical presentations of people with age-associated neurocognitive disorders. This book is organized into three sections: (1) core concepts, (2) dementia syndromes, and (3) disease management. The chapters in section one focus on clinical knowledge and skills applicable across all dementias, including the diagnostic interview and neurologic examination, frequently used cognitive screening measures, neuropsychological assessment, neuroimaging, and differential diagnosis. Chapters in section two review the most common dementia syndromes and cover epidemiology, neuropathology, biomarkers, genetics, and clinical signs and symptoms, providing at least one illustrative case. The final section presents the latest evidence-based interventions from risk management to pharmacologic and nonpharmacologic approaches, while also addressing safety considerations, legal issues, palliative and advanced care planning, and attending to caregivers.

    £79.00

  • Parkinsons Disease and other Movement Disorders

    Oxford University Press Parkinsons Disease and other Movement Disorders

    1 in stock

    Book SynopsisThis book allows the movement disorder clinician or therapist access to concise, practical, comprehensive and expert information on movement disorder diagnosis and treatment, in a convenient handbook form.Trade ReviewReview from previous edition 'The individual segments are well-edited, illustrative, and accompanied by excellent narration.' * Neurology *'The book's clinical focus and detailed sections on theraputics are its biggest assets.' * Neeraj Kumar, MD, Neurology *'...a comprehensive, portable, and robust reference on Parkinson's disease and other movement disorders...a more useful way of accessing movement disorders-related information than even Google. Recommended.' * ACNR *Table of Contents1. Approach to patients with movement disorders ; 2. Anatomy and function of the basal ganglia ; 3. Parkinson's disease ; 4. Atypical parkinsonism ; 5. Tremor ; 6. Tics ; 7. Chorea ; 8. Myoclonus ; 9. Dystonia ; 10. Drug-induced movement disorders ; 11. Paroxysmal movement disorders ; 12. Movement disorders and ataxia ; 13. Movement disorders and sleep ; 14. Other dyskinetic syndromes ; 15. Functional (Psychogenic) movement disorders ; 16. Startle and stiff-person syndromes

    1 in stock

    £64.00

  • Stroke The Facts The Facts Series

    Oxford University Press Stroke The Facts The Facts Series

    1 in stock

    Book SynopsisStroke is the second most common cause of death worldwide. This fully-updated new edition provides clear facts and practical advice as to why strokes occur and how they can be prevented. Supplemented with case studies, the book concentrates on important facts, reliable evidence, practical advice, and up-to-date treatments.Trade ReviewReview from previous edition ... an interesting addition to the available material for patient information ... very comprehensive ... useful to anyone wanting to understand a long-term condition - and that would include medical staff. * Pulse GP Magazine *This isn't a 'soft' book on stroke that holds the hand of the reader from diagnosis to treatment - it's dry, full of medical studies and hits you with the facts. But don't let this put you off. Full of tips on how to recognise stroke and the latest in research into therapies, it's well worth persevering with. * Ros Holness in The Daily Mail *This engaging little book is highly readable and packed with up-to-date information ... it covers clearly, concisely and quite comprehensively the aspects of risk factor management, causes and pathology of stroke, ... and answers many questions that would benefit the patients themselves. ... It would be an invaluable aid to junior doctors working on a stroke unit, and it clearly deserves a space on the bookshelf. * Diane Ames, Age and Ageing *Table of Contents1: What is stroke? 2: How common is stroke? 3: Who gets strokes? 4: The causes of stroke 5: What can be done for people who have a stroke? 6: Rehabilitation after stroke 7: Living after stroke 8: How do you prevent stroke?

    1 in stock

    £20.49

  • Dementia

    Oxford University Press Dementia

    2 in stock

    Book SynopsisAs more of us live longer, the fear of an old age devastated by brain diseases like dementia is growing. Many people are already facing the challenges posed by these progressive and terminal conditions, whether in person or because they are caring for loved ones. Dementia is now the fifth most common cause of death across the world. It is small wonder that understanding, preventing, and finally curing these illnesses is now a global priority. Recent advances in brain research have given scientists a better chance than ever of finding ways to help patients, carers, and clinicians dealing with dementia. Yet there is still no effective treatment. Why has progress been so slow? And what can we all do to reduce our chances of getting the disease? In this Very Short Introduction Kathleen Taylor offers a guide to the science of dementia and brain ageing. Never forgetting the human costs of brain disorders - movingly illustrated throughout the book - she also discusses their costs to society. Clearly explaining the research, she sets out the main ideas which have driven dementia science, and the new contenders hoping to make a breakthrough. Taylor also looks at risk factors, and how to lower our chances of succumbing to dementia. Assessing current and potential treatments, including both drugs and other approaches, she explains, clearly and gently, what help is available for someone who is diagnosed with dementia, and how to boost the chances of living well with the condition.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.Table of Contents1: The challenge of dementia 2: What causes dementia? 3: Beyond amyloid 4: Risk factors 5: Diagnosis and treatment 6: The future of dementia References Further reading Useful organisations and websites

    2 in stock

    £9.49

  • Best of Five MCQs for the Geriatric Medicine SCE

    Oxford University Press Best of Five MCQs for the Geriatric Medicine SCE

    15 in stock

    Book SynopsisCandidates can prepare with confidence for the Geriatric Medicine Specialty Certificate Examination with this revision guide designed specifically for the exam. Containing 300 Best of Five questions, the content is carefully mapped to the curriculum ensuring comprehensive preparation. The questions mirror the format of those candidates can expect to find in the exam, and cover all of the key topics, including dementia and delirium, palliative care, nutrition, and stroke. Explanatory answers include references to guidelines and other sources to enable further reading and study.The second edition addresses the latest clinical guidelines and supporting literature, Non-vitamin K Antagonist Oral Anticoagulants (NOACs), and changes in health and social care policy. This new edition is also suitable for candidates preparing for the Diploma in Geriatric Medicine exam. Providing a thorough assessment of the reader''s geriatric medicine knowledge, this is the only revision guide candidates will need to pass the Geriatric Medicine Specialty Certificate Examination first time.Table of Contents1: Exam 1 Questions and Answers 2: Exam 2 Questions and Answers 3: Exam 3 Questions and Answers

    15 in stock

    £51.30

  • Best of Five MCQs for the Geriatric Medicine SCE

    OUP Oxford Best of Five MCQs for the Geriatric Medicine SCE

    15 in stock

    Book SynopsisBest of Five MCQs for the Geriatric Medicine SCE is the first revision guide designed specifically for this new high-stakes exam. It contains 300 best of five questions with explanatory answers, each accurately reflecting the layout of questions in the exam.

    15 in stock

    £54.00

  • Geriatric Psychiatry

    Oxford University Press Geriatric Psychiatry

    15 in stock

    Book SynopsisPart of the Pittsburgh Pocket Psychiatry series, this volume comprehensively and definitively addresses geriatric psychiatry, focusing on depression, dementia, anxiety as well as managing the caregivers. Additional chapters cover psychotherapy, legal issues, alcohol and drug use, and chronic pain management. Designed to be a highly practical, clinical guide for practitioners, each chapter is clearly written by one or more faculty members from Western Psychiatric Institute and Clinic, many of whom are recognized experts in their field. Self-assessment questions help the student learn the material.Trade ReviewThe range of chapters provides a comprehensive examination of the area of geriatric psychiatry, truly distinguishing it as a unique field and not just as an application of general psychiatry to the geriatric patient... an excellent addition to the literature on geriatric psychiatry. As a physician dually trained in internal medicine and psychiatry who also completed a geriatric medicine fellowship, I will be recommending this book to all of my colleagues in geriatric medicine, geriatric psychiatry, general psychiatry, family practice, and even internists in primary care. * Steve Paschos for Doody's, July 2013 *I could find little to fault in this excellent text ... All who are working or training to work with old people affected by psychiatric and cognitive disorders (i.e. nearly every health professional in the world) should try to get their hands on this book and then read it from cover to cover. * David Ames, Journal of International Psychogeriatrics *Table of ContentsChapter 1 Clinical Approach to the Geriatric Psychiatry Patient ; Jamie Tew, Mark Miller and Sharon Altman ; Chapter 2 Psychiatry and Medicine at the Geriatric Crossroads ; Eric Rodriguez ; Chapter 3 Legal Issues Geriatric Psychiatrists Should Understand ; Robert Wettstein ; Chapter 4 Aging Changes and Pharmacotherapy Principles ; Tanya Fabian ; Chapter 5 Delirium ; LalithKumar K. Solai ; Chapter 6 Evaluation and Management of Cognitive Disorders and Dementia Part I ; Eric McDade and Oscar Lopez ; Chapter 7 Evaluation and Management of Cognitive Disorders and Dementia Part II ; Eric McDade and Oscar Lopez ; Chapter 8 Late-Life Anxiety Disorders ; Carmen Andreescu ; Chapter 9 Late-Life Depression: Evidenced Based Treatment ; Mark Miller, Charles F. Reynolds III, Ariel Gildengers, Ellen Whyte and Carmen Andreescu ; Chapter 10 Psychotherapeutic Approaches for Depression, Cognitive Impairment and ; Personality Disorders in Late-Life ; Mark Miller and Jennifer Morse ; Chapter 11 Late-Life Psychosis ; LalithKumar K. Solai ; Chapter 12 Late-Life Sleep Disorders ; Anne Germain ; Chapter 13 Late-Life Substance Use Disorders ; Antoine Douaihy ; Chapter 14 Geriatric Psychiatry Management of Chronic Pain ; Jordan Karp and Mark Miller ; Chapter 15 Long Term Care Geriatric psychiatry ; Ann Zachariah ; Chapter 16 Psychosocial Factors, Health, and Quality of Life ; Richard Schulz and Rick Morycz ; Future Directions ; Mark Miller, Lalith Kumar Solai, Carmen Andresscu and Charles Reynolds ; Index

    15 in stock

    £62.25

  • Neuroinfections

    Oxford University Press Neuroinfections

    15 in stock

    Book SynopsisNeuroinfections presents 35 subjects, each with a different neurologic infectious or inflammatory disorder. A short vignette provides salient clinical symptoms and signs, laboratory studies, spinal fluid and imaging findings for each patient. A highly focused discussion leads the reader to the final diagnosis. Important features of the history, neurologic examination, findings on CSF and imaging are emphasized. There is no other book that provides a careful case description that includes all the neurologic features of 19 neurologic diseases produced by virus, as well as cases of bacterial meningitis and other infections produced by spirochetes, protozoans and prions, as well as inflammatory diseases of the nervous system of unknown etiology. A unique feature of the book is that every patient described is a real-time case that the author has seen or on whom he provided consultation. Anyone who reads every case in this book will know the essentials needed to diagnose and care for patientTrade ReviewThis is a useful, easy to read, 'charming' book highlighting the clinical presentation of common and not so common infections of the nervous system, written by one of the leaders in clinical and research neurovirology. By using the format of clinical vignettes the reader is immediately engaged and then is asked and told what to do next... Treatment is evidence based when such evidence is available and when not; the reader is provided the approach of an experienced neurologist with a career in neuroinfectious diseases... While this book serves as a resource to which one return when confronted with a patient with a clinical presentation that might well be due to infection or inflammation of the nervous system, it is also possible to simply read the book just for 'enjoyment'. I know I did. -- Robert P Lisak, MD, FRCP, FAAN, Parker Webber Chair in Neurology, Professor of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, MI Dr Gilden has written a remarkably concise and useful guide to the management of a wide range of infections of the nervous system... and he has managed the very difficult feat of giving a wealth of key information about each condition while at the same time getting over with commendable clarity all the key aetiological, clinical and management points... I am unaware of any previous book on this subject, in particular in relation to virus infections of the nervous system, which manages to present such an integrated, comprehensive, and practical approach as has been achieved here. This book will undoubtedly be of considerable value to a wide range of readers including neurologists, infectious diseases and general medicine consultants, specialist trainees, medical students and other health professionals. -- Professor Peter GE Kennedy CBE, MD, PhD, DSc, FRCP, FMedSci, FRSE, Burton Chair of Neurology, Glasgow University, College of Medical, Veterinary and Life Sciences, Scotland, UK Thirty-five succinctly analyzed and cogently discussed vignettes are written by a world renowned clinical neurologist with extensive experience in infections and inflammatory diseases of the nervous system. The cases are practical, well-written and packed with important teaching points and clinical pearls. The author does not shy away from controversy and provides strong opinions on management when scientific data is not available. This is a book that all clinical neurologists should keep on their desk. -- Professor Oded Abramsky, MD, PhD, FRCP, Chairmen Emeritus of the Department of Neurology, Dean Emeritus of the Hebrew University Hadassah Medical School, Jerusalem, Israel "Neuroinflammatory diseases are among the most important, inherently interesting, sometimes exotic, constantly changing, and always challenging problems in medicine. In this wonderful volume, Don Gilden has brought together a lifetime of clinical experience to highlight, in an accessible case method format, both the common and the rare. The result is a unique survey of the field by one of its true giants, with insightful pedagogical insights that burst forth from every page. There is new, practical information here for everyone, from students to the most seasoned practitioner." -- Stephen L. Hauser, MD, Professor & Chair, Department of Neurology, University of California, San Francisco, CA In this book, Dr. Gilden addresses 35 different cases of clinical infectious and inflammatory diseases of the nervous system through highly insightful presentations. Each case tells a practical story of how such diseases begin, are diagnosed and are managed and treated. -- Howard L. Lipton, MD, Department of Microbiology-Immunology, University of Illinois at Chicago, Chicago, IL Dr. Gilden has provided a very engaging approach to helping clinicians who care for individuals with a wide variety of infections and inflammatory diseases of the nervous system. The challenge of a case description is followed by his analysis of pathogenesis, then management, and finally bulleted "Key Points to Remember." Brief bibliographies list carefully selected references. Neuroinfections will be most useful to neurology and internal medicine residents, and to experienced clinicians who may not be dealing with these disorders on a daily basis. -- Donald Silberberg, MD, Professor and Chair Emeritus, Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA "This volume will have a significant place in the clinician's library. The format of 1) a case report, 2) what to do now (diagnosis and treatment), 3) key points about the infection and 4) further reading will serve as an excellent manual for students, residents and clinicians. It is clearly and concisely written and will be important in both academic settings and to private practitioners." -- Leslie P. Weiner, MD, Department of Neurology, Keck Medical Center of USC, University of Southern California, Los Angeles, CA "A helpful and informative summary of major etiologies of neurologic infections, in an enjoyable, easy-to-read format." -- Emerging Infectious Diseases "The narrative is very clear and well written and flows smoothly. ... It is an excellent introduction to a complicated and difficult field and should be available to the neurology resident and general neurologist as well as the specialist." --Journal of the Neurological SciencesTable of ContentsSECTION I Virus infections ; 1. Varicella Zoster Virus Vasculopathy ; 2. Aseptic Meningitis ; 3. Herpes Simplex Virus Encephalitis ; 4. HIV Encephalitis ; 5. Ramsey Hunt Syndrome ; 6. West Nile Virus Meningoencephalitis ; 7. Progressive Outer Retinal Necrosis ; 8. Rabies ; 9. Cytomegalovirus Polyradiculoneuropathy ; 10. Varicella Zoster Virus Myelopathy ; 11. Subacute Sclerosing Panencephalitis ; 12. Eastern Equine Encephalitis ; 13. Human Herpesvirus-6 Encephalitis ; 14. Zoster Sine Herpete ; 15. Human T-lymphotropic Virus-1 (HTLV-1) Myelopathy ; 16. Herpes Simplex Virus-2 Meningitis ; 17. HIV Vacuolar Myelopathy ; 18. Progressive Multifocal Leukoencephalopathy ; 19. Postherpetic Neuralgia ; SECTION II Bacterial, Spirochetal, Protozoan and Prion Disorders of the Nervous System ; 20. Listeria Rhombencephalitis ; 21. Neurosyphilis ; 22. Tuberculous Meningoencephalitis ; 23. Raeder's Paratrigeminal Syndrome ; 24. Fungal Meningitis ; 25. Whipple's Disease ; 26. Lyme Disease ; 27. CNS Toxoplasmosis ; 28. Cysticercosis ; 29. Jakob-Creutrzfeldt Disease ; SECTION III Inflammatory Diseases of the Nervous System of Unknown Etiology ; 30. Acute Disseminated Encephalomyelitis ; 31. Behcet's Disease ; 32. CNS Sarcoidosis ; 33. Giant Cell (Temporal) Arteritis ; 34. Melkersson-Rosenthal Syndrome ; 35. Vogt-Koyanagi-Harada Syndrome (Uveomeningoencephalitis)

    15 in stock

    £39.99

  • Aging Our Way

    Oxford University Press Aging Our Way

    15 in stock

    Book SynopsisAmerica is quickly going grey. There are more Americans alive today over the age of 80 than ever before in our history; by 2030, that number is expected to almost triple. But when we discuss how long people live, we must also consider how well they live. Aging Our Way follows the everyday lives of 30 elders (ages 85-102) living at home and mostly alone to understand how they create and maintain meaningful lives for themselves. Through extensive interviews, Meika Loe explores how elders navigate the practical challenges of living as independently as possible while staying healthy, connected, and comfortable. Aging Our Way celebrates these men and women as they really are: lively, complicated, engaging people finding creative ways to make their aging as meaningful and manageable as possible. Written with remarkable warmth and depth of understanding, Aging Our Way offers a vivid look at a group of people who too often remain invisible--those who have lived the longest - and all they have Trade ReviewAmericans are living longer lives today than ever before. But are these quality years? How are we experiencing 'these additional years' in our 80s, 90s, and even 100s? In Meika Loe's Aging Our Way, men and women tell how they are making the best of their time, even with personal limitations. These 'ways of aging' are summed up as lessons for reflection and action. I urge you to read and share this inspiring book with others for it enriches understanding of life paths that many will follow. * Glen H. Elder, Jr., Howard W. Odum Distinguished Research Professor of Sociology, University of North Carolina at Chapel Hill *Loe's writing is clear, jargon-free, and warm-she clearly likes and often admires her subjects. She has done an excellent job in organizing her book topically and lets her subjects speak for themselves, then distills their most important points. While there are few startling revelations, there is a great deal of wisdom. * Publisher's Weekly *Useful for its thoroughness, examples of resiliency, and attention to this growing phenomenon. * CHOICE *A lively, engaging, and moving read. Loe shows how the personal resources needed to cope with aging are closely tied to structural factors like race, class, gender, birth cohort, and socioeconomic status. Nearly any reader will find Aging Our Way relevant to their own life or the lives of their aging parents or relatives. * Deborah Carr, Professor of Sociology, Rutgers University *In this delightfully written book, Meika Loe illustrates how we continue to develop and become more diverse as we age. Aging Our Way is an engagingly written introduction to this new understanding of aging and will serve its readers well. * Peter V. Rabins, MD, MPH, Johns Hopkins School of Medicine, co-author of The 36-Hour Day *Table of ContentsPrologue: 30-60-90: A Short Meditation on Age and Perspective ; Introduction: Living at Home and Making it Work ; Lesson 1: Continue to Do What You Did ; Lesson 2: (Re) Design Your Living Space ; Lesson 3: Live in Moderation ; Lesson 4: Take Time for Self ; Lesson 5: Ask for Help; Mobilize Resources ; Lesson 6: Connect with Peers ; Lesson 7: Resort to Tomfoolery ; Lesson 8: Care for Others ; Lesson 9: Reach out to Family ; Lesson 10: Get Intergenerational; Redefine Family ; Lesson 11: Insist on Hugs ; Lesson 12: Be Adaptable ; Lesson 13: Accept and Prepare for Death ; Conclusion: New Perspectives on the Oldest Old ; Postscript: On Doing Ninety (by Ann, research participant) ; Epilogue: Updates on Study Participants ; Appendix: Best Practices in Supporting Aging in Place ; References ; Index

    15 in stock

    £26.99

  • Analyses in the Economics of Aging NBER National

    The University of Chicago Press Analyses in the Economics of Aging NBER National

    10 in stock

    Book SynopsisCarefully compiled and containing some of the most cutting-edge research and analysis available, this volume should be of interest to any specialist or policymaker concerned with ongoing changes in savings and retirement behaviors.

    10 in stock

    £104.00

  • Gerontology and Geriatrics for NPs and PAs

    Elsevier - Health Sciences Division Gerontology and Geriatrics for NPs and PAs

    15 in stock

    Book SynopsisTable of ContentsSection I AGING 1 Biological and Physiological Change Theories 2 Normal Aging 3 Principles of Care 4 Ethical Issues in Care 5 Sexuality in Older Adults Section II HEALTH PROMOTION AND DISEASE PREVENTION 6 Preventive Screenings and Immunizations 7 Promotion of Healthy Aging 8 Medication Use in Older Adults 9 Complementary and Integrative Therapies for Older Adults Section III ASSESSMENT AND MANAGEMENT OF HEALTH PROBLEMS COMMON TO OLDER ADULTS 10 Clinical Assessment: Cognitive, Psychological, Social, Functional, and Medications 11 Common Geriatric Syndromes 12 Sensory Changes 13 Chronic Conditions 14 Infectious Diseases 15 Acute, Emergent, and Urgent Conditions 16 Musculoskeletal and Rheumatologic Conditions in the Older Adult 17 Cancer 18 Mental Health/Behavioral Health Section IV CARE SYSTEMS FOR PROBLEMS OF OLDER ADULTS 19 Home Care 20 Acute Care 21 Long-Term Care 22 Palliative Care and Hospice Appendix 1: Tools Appendix 2: IPEC Competencies Index

    15 in stock

    £74.69

  • The Mental Status Examination Handbook

    Elsevier - Health Sciences Division The Mental Status Examination Handbook

    15 in stock

    Book Synopsis

    15 in stock

    £64.79

  • Cardiac Rehabilitation An Issue of Clinics in

    Elsevier Health Sciences Cardiac Rehabilitation An Issue of Clinics in

    Out of stock

    Book Synopsis

    Out of stock

    £70.29

  • Hams Primary Care Geriatrics

    Elsevier - Health Sciences Division Hams Primary Care Geriatrics

    15 in stock

    Book SynopsisTrade Review"This book is well done and easy to use. It includes cases in each of the chapters, which many readers will find relatable and will add to their learning. In terms of content, this book truly is well done." © Doody's Review Service, 2021, Belinda Setters, MD, MS, FACP, AGSF (Robley Rex VA Medical Center) Doody's Score: 94-4 Stars!Table of ContentsUNIT ONE: PRINCIPLES AND PRACTICE 1. Principles of Primary Care of Older Adults 2. Interprofessional Team Care 3. Assessment 4. Wellness and Prevention 5. Advanced Cultural Competency in Caring for Geriatric Patients 6. Appropriate Prescribing 7. Ethics 8. Financing and Organization of Health Care 9. Billing and Coding 10. Hospital Care 11. Long-Term Care 12. Home Care 13. Rehabilitation 14. Palliative Care UNIT TWO: GERIATRIC SYNDROMES AND COMMON SPECIAL PROBLEMS 15. Emergency Care 16. Delirium 17. Alzheimer's Disease and Other Dementias 18. Depression 19. Balance, Gait and Mobility 20. Falls 21. Dizziness 22. Syncope 23. Urinary Incontinence 24. Constipation and Fecal Incontinence 25. Hearing Impairment 26. Visual Impairment and Eye Problems 27. Persistent Pain 28. Malnutrition and Feeding Problems 29. Frailty 30. Pressure Ulcers 31. Sleep Disorders 32. Sexual Health 33. Mistreatment and Neglect 34. Alcoholism 35. Driving UNIT THREE: SELECTED CLINICAL PROBLEMS OF THE ORGAN SYSTEMS 36. Hypertension 37. Coronary Artery Disease and Atrial Fibrillation 38. Congestive Heart Failure 39. Peripheral Vascular Disease 40. Transient Ischemic Attacks and Stroke 41. Diabetes Mellitus 42. Thyroid Disorders 43. Osteoporosis 44. Arthritis and Related Disorders 45. Foot Problems 46. Cancer 47. Anemia 48. Pulmonary Disease 49. Infectious Diseases 50. The Acute Abdomen 51. Benign Prostate Disease 52. Parkinson's Disease 53. Oral Disorders 54. Skin Problems

    15 in stock

    £80.99

  • Gastroenterology An Issue of Clinics in Geriatric Medicine

    1 in stock

    £66.59

  • Practical Aspects of Cognitive Impairment and the

    Elsevier Health Sciences Practical Aspects of Cognitive Impairment and the

    Out of stock

    Book SynopsisTable of ContentsThe Burden of Dementia Spectrum Disorders and Associated Comorbid and Demographic Features Office- and Bedside-based Screening for Cognitive Impairment and the Dementias:Which Tools to Use, Interpreting the Results, and What Are the Next Steps? Formal Neuropsychological Testing: Test Batteries, Interpretation, and Added Value in Practice Brain Networks, Clinical Manifestations, and Neuroimaging of Cognitive Disorders:The Role of Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), and Other Advanced Neuroimaging Tests Blood and Cerebrospinal Fluid Biomarkers in Vascular Dementia and Alzheimer's Disease: A Brief Review What Are the Key Diagnostic Cognitive Impairment and Dementia Subtypes and How to Integrate all of the Diagnostic Data to Establish a Diagnosis? Neuropathology of the Common Forms of Dementia Vascular and Nonvascular Mechanisms of Cognitive Impairment and Dementia The Role of Vascular Risk Factors in Cognitive Impairment and Dementia and Prospects for Prevention Treatment of Vascular and Neurodegenerative Forms of Cognitive Impairment and Dementias Brain Reserve, Resilience, and Cognitive Stimulation Across the Lifespan: How Do These Factors Influence Risk of Cognitive Impairment and the Dementias? Diagnostic and Management Strategies for Common Neurobehavioral and Psychiatric Disturbances Among Patients with Cognitive Impairment and the Dementias Harmonizing Ethno-Regionally Diverse Datasets to Advance the Global Epidemiology of Dementia

    Out of stock

    £70.19

  • Tom Kitwood on Dementia A Reader and Critical

    Open University Press Tom Kitwood on Dementia A Reader and Critical

    15 in stock

    Book Synopsis"The book will be valuable for undergraduate and postgraduate students, researchers and lecturers involved in the field of dementia care and the health-care sciences. Furthermore, it provides a useful resource for clinicians who wish to explore their understanding of 'personhood', person-centred care and the nature of Kitwood's critical appraisal of how 'care' should be constructed and delivered."Ageing and Society"Baldwin and Capstick have produced an honest appraisal that is undeniably a reader and critical commentary, and have not shirked from any responsibilities. ... This paperback would serve two distinct strands of readership equally well - those coming afresh to dementia care, or practitioners steeped in the concepts, who are looking to reanalyse and consider future developments. As such, it is difficult to underestimate its value."Nursing in PracticeHow does Kitwoodâs work contribute to our understanding of âthe dementing proceTable of ContentsAcknowledgements About the EditorsIntroductionSection 1: Critique of the standard paradigmSection 2: Ill-being, well-being and psychological need Section 3: PersonhoodSection 4: Organisational culture and its transformation BibliographyReferences

    15 in stock

    £26.59

  • Psychotropic Drugs and The Elderly

    WW Norton & Co Psychotropic Drugs and The Elderly

    2 in stock

    Book SynopsisPsychotropic drugs are used widely with the elderly, but formal knowledge and training are often poor. With a focus on geriatric considerations such as medical issues, disabilities and nursing-home situations, this handbook gives clinicians the facts they need to work with elderly clients.

    2 in stock

    £49.39

  • Geriatric Dental Medicine An Issue of Clinics in

    Elsevier Health Sciences Geriatric Dental Medicine An Issue of Clinics in

    1 in stock

    Book SynopsisTable of ContentsDemographics and Oral Health Care Utilization for Older Adults Oral Health Disparities and Inequities in Older Adults Physiology of Aging of Older Adults: Systemic and Oral Health Considerations-2021 Update Geriatric Phenotypes and Their Impact on Oral Health Poor Oral Health in the Etiology and Prevention of Aspiration Pneumonia Oral Implications of Polypharmacy in Older Adults Cognitive Impairment in Older Adults and Oral Health Considerations: Treatment and Management Consideration in Planning Dental Treatment of Older Adults Interdisciplinary Education and Health Care in Geriatric Dental Medicine Innovations in Geriatric Oral Health Care

    1 in stock

    £70.19

  • Age Differences in Word and Language Processing

    Elsevier Science Age Differences in Word and Language Processing

    1 in stock

    Book Synopsis

    1 in stock

    £128.25

  • Prescribing for Elderly Patients

    John Wiley & Sons Inc Prescribing for Elderly Patients

    10 in stock

    Book SynopsisPrescribing for elderly patients is complex and challenging for many reasons. Prescribing for Elderly Patients assists clinicians working with the elderly to make accurate diagnoses and safely prescribe the correct dose of the appropriate medication.Table of ContentsList of Contributors. Foreword. Preface. Acknowledgement. 1 Clinical Pharmacology of Ageing (Arduino Mangoni, Paul Jansen and Stephen Jackson). Epidemiology. Age-related changes in pharmacokinetics. Age-related changes in pharmacodynamics. Adverse drug reactions and drug interactions. Adherence. Polypharmacy versus appropriate prescribing. Over-the-counter medicines. Prescribing audit. Medication review. Undertreatment. References. 2 Dementia, Delirium, Agitation and Behavioural Problems (Catherine Bryant). Dementia. Delirium. Agitation and behavioural problems. References. 3 Depression in Elderly Patients (Richard Weeks, Ross Kalucy and Jo Hill). Introduction. Aetiology. Signs and symptoms. Diagnosis. Therapy. References. 4 Psychotic Illness in Elderly Patients (Ross Kalucy, Jo Hill and Richard Weeks). Introduction. Aetiology. Symptoms and signs. Diagnosis. Therapy. Key points. References. 5 Sleep Disorders in the Elderly: the Pros and Cons of Prescribing (R. Doug McEvoy and Karin S. Nyfort-Hansen). Insomnia. Restless legs syndrome and periodic limb movements of sleep. Nocturnal leg cramps. REM behaviour disorder. References. 6 Stroke (Joseph A. Harbison and Gary A. Ford). Introduction. Aetiology. Modifiable risk factors for stroke. Therapy. Key points. References. 7 Orthostatic Hypotension, Postprandial Hypotension and Syncope in Older Patients (René W.M.M. Jansen). Orthostatic hypotension in older patients. Key points. Postprandial hypotension in older patients. Key points. Syncope in older patients. Key points. Guidelines. References. 8 Parkinson’s Disease (Gerrit Tissingh and Erik Ch. Wolters). Introduction. Symptoms and signs of PD. Aetiology and pathology. Diagnosis. Therapy. Key points. Links. References. 9 Epilepsy (John O. Willoughby, Joseph Frasca and Emma M. Whitham). Introduction. Aetiology. Symptoms and signs. Diagnosis. Therapy. Newer anti-epileptic drugs. Safety of anti-epileptic drugs. Therapy scheme of the advised drugs. Clinically-important drug interactions within anti-epileptic drugs. Clinically-important drug interactions with other drugs. Important adverse effects. Drug withdrawal. Key points. References. 10 Hypertension (Sanjeev Khindri and Stephen Jackson). Introduction. Aetiology. Symptoms and signs. Diagnosis. Investigation. Therapy. Clinical pharmacology of antihypertensive therapy. Key points. Links. References. 11 Lipid-Lowering in the Elderly Patient (Anthony S. Wierzbicki). Introduction. Aetiology. Symptoms and signs. Diagnosis. Therapy. Statins. Fibrates. Nicotinic acid. Ezetimibe. Bile acid sequestrants. Omega-3 fatty acids. Guidelines. Key points. Links. References. 12 Acute Coronary Syndrome (Derek Yiu and Arduino Mangoni). Introduction. Aetiology. Symptoms and signs. Diagnosis. Therapy. Therapy scheme of the advised drugs. Key points. Guidelines. Acknowledgements. References. 13 Heart Failure (Arduino Mangoni). Introduction. Epidemiology. Aetiology. Clinical presentation. Diagnosis. Therapy. Key points. Guidelines. Acknowledgements. References. 14 Atrial Fibrillation and Other Rhythm Disturbances in the Elderly (Abhay Bajpai, Irina Savelieva and A. John Camm). Introduction. Atrial arrhythmias. The epidemiology and cost of AF. The mechanism of atrial tachyarrhythmias. Symptoms and signs. Diagnosis. Classification of AF. Causes of AF. Principles of management of AF. Treatment of acute onset AF. Suppression of paroxysms of AF. Strategies in persistent AF—rate versus rhythm control. Rate control in permanent AF. Risk of stroke and antithrombotic therapy in AF. Non-pharmacological techniques to prevent thrombus formation. Key points. References. 15 Valvular Heart Disease (Andrew T. Elder). Introduction. Infective endocarditis. Prevention of endocarditis. Diagnosis and treatment of endocarditis. Prevention of thromboembolism. Prevention of progression of degenerative valvular disease. References. 16 Anticoagulants for Thrombosis and Embolism in the Elderly (Alexander Gallus and Dolly Daniel). Introduction. The anticoagulants. Thrombosis in the elderly and indications for anticoagulants. References. 17 Haematological Disorders (Bryone J. Kuss and Sabria Alhashami). Introduction. Anaemia. Vitamin B12 and folic acid deficiencies. Thrombocytopenia. Myelodysplastic syndromes. Acute leukaemia. Lymphoproliferative conditions. Multiple myeloma. Key points. References. 18 COPD and Asthma in the Elderly (Martin Connolly and Tina L. Davies) Risk factors and triggers. Presentation and diagnosis. Objective tests. Differential diagnoses. Management of COPD and asthma. Acute asthma. Management of exacerbations of COPD. Management of stable COPD. Conclusion. Key Points. Learning Resources. Guidelines. References. 19 Pneumonia in the Elderly (Peter A. Frith and Karin S. Nyfort-Hansen). Introduction. Epidemiology. Aetiology and pathogenesis. Symptoms and signs. Diagnosis. Patient assessment. Therapy. Important considerations for drug usage. Prevention. References. 20 Therapeutic Aspects of Pulmonary Tuberculosis (Paul van den Brande). Introduction. Pathogenesis. Presentation of tuberculosis in the elderly. Diagnosis of tuberculosis. Treatment of tuberculosis. Treatment of latent tuberculosis infection. Key points. References. 21 Interstitial Lung Disease in the Elderly (Jeffrey Bowden). Introduction. Presentation of interstitial lung disease. Particular problems in the elderly. General comments with regard to therapy. Assessing the response to therapy. Drugs used in ILD. Treatment for specific forms of lung disease. Key points. Links. References. 22 Lung Cancer in the Elderly (Jeffrey Bowden). Introduction. Aetiology. Symptoms and signs. Diagnosis and staging. Goals of therapy. Chemotherapeutic agents. Treatment protocols for NSCLC. Non cytotoxic agents: EGFR Inhibitors. Treatment of small cell carcinoma. Treatment of mesothelioma. Anti-emetic therapy. Key Points. Guidelines. References. 23 Nutritional Disorders and the Older Person (Robert K. Penhall and Renuka Visvanathan). Introduction. Obesity and the older person. Nutritional frailty. Under-nutrition in older people. Screening and assessment of under-nutrition. The management of the under-nourished older person. Monitoring and change. Conclusion. References. 24 Mouth and Dental Disorders (Cees de Baat and Isaac van der Waal). Introduction. Periodontal disease. Dental caries. Odontogenic infections. Alveolar osteitis. Xerostomia and hyposalivation. Candidiasis. Angular cheilitis. Denture stomatitis. Burning mouth syndrome. Recurrent aphthous stomatitis. Recurrent herpes simplex. Oral lichen planus. 25 Swallowing Disorders and Medication in the Elderly (Eddy Dejaeger). Introduction. Normal deglutition. Changes with Age. Aetiology of deglutition disorders. Symptoms and signs. Diagnosis. Therapy. Deglutition disorders and medication. Key points. Links. References. 26 Upper Gastrointestinal Disorders (Geoffrey S. Hebbard). Gastrooesophageal reflux disease. Oesophageal motility disorders. Non-cardiac chest pain. Oesophageal infections. Pill-induced oesophagitis. Peptic ulcer disease. Gastritis. Non-ulcer dyspepsia. References. 27 Gastric Emptying in Older Patients (Robert J. Fraser). Introduction. Aetiology of disturbed gastric motor function in ageing. Symptoms and signs. Diagnosis. Therapy. Therapy scheme of advised drugs for gastroparesis. Key points. Guidelines. Effect of healthy ageing on appetite regulation—anorexia of ageing. References. 28 Lower Gastrointestinal Disorders (Daniel L. Worthley, Graeme P. Young and Robert J. Fraser). Malabsorption. Inflammatory bowel disease. Diverticulosis. Mesenteric ischaemia. Constipation. Diarrhoea and faecal incontinence. Haemorrhoids. References. 29 Abdominal Malignancies (Sarah Zaidi and Guy Chung-Faye). Introduction. Epidemiology. Aetiology. Symptoms and signs. Therapy. Chemotherapy. Key points. Links. References. 30 Liver Diseases in the Elderly (Réme Mountfield and Alan J. Wigg). Introduction. Physiological changes associated with ageing. Drug induced liver disease. Cirrhosis. Alcoholic liver disease. Non-alcoholic steatohepatitis (NASH). Hepatitis C. Hepatitis B. Liver transplantation. References. 31 Disorders of the lower urinary tract (Adrian Wagg). Pathophysiology. Incontinence subtypes. Treatment cessation. Assessment with a bearing on drug addition or withdrawal. Rectal examination. Vaginal examination. The pharmacological treatment of urinary incontinence. Cognition and antimuscarincs. Bladder outflow tract obstruction. Other pharmacological measures. Stress urinary incontinence. Summary. References. 32 Management of Benign Prostatic Hyperplasia in Elderly Men (Ming Liu and Gordon H. Muir). Assessment. Prostate specific antigen (PSA). Urinary retention. Nocturnal frequency. Treatment. References. 33 Management of Erectile Dysfunction in the Elderly (Kevin Dennison). Introduction. Prevalence and aetiology of ED. Physical or psychogenic? Diagnosis and assessment of ed in primary care. Treatment options. Key points. References. 34 Benign Gynaecological Disorders (Maria Vella, James Balmforth and Linda Cardozo). Urogenital atrophy. Prolapse. Traditional anatomical site prolapse classification. Urinary incontinence. Detrusor overactivity. Drug therapies. Lichen sclerosis. Lichen planus. References. 35 Breast Cancer in Elderly Patients (Bogda Koczwara). Introduction. Presentation and diagnosis—special considerations in elderly patients. Management of breast cancer. Management of early breast cancer. Treatment of advanced breast cancer. Supportive care during breast cancer treatment. Breast cancer therapeutics in an elderly patient. Conclusion. Key points. References. 36 Pharmacological Management of Endocrine Conditions in the Elderly Patient (Nikolai Petrovsky). Introduction. Diabetes aetiology. Diabetes symptoms and signs. Diabetes diagnosis. Type 2 diabetes management. Pharmacokinetic and pharmacodynamic data of diabetes medications in elderly patients. Clinically important drug interactions within diabetes drugs. General adverse effects of diabetes medications in elderly patients. Specific adverse effects and clinically-important drug interactions of diabetes drugs. Pituitary adenomas. Thyroid disease. Hyperparathyroidism. Hormone replacement. Endocrine disease in the elderly—key points. Further Reading. 37 Rheumatoid Arthritis, Osteoarthritis, Polymyalgia Rheumatica, Gout and Pseudogout (E. Michael Shanahan and Stephen Hedger). Rheumatoid arthritis. Key points in rheumatoid arthritis. Osteoarthritis. Key points in osteoarthritis. Polymyalgia rheumatica. Key points in PMR. Gout and calcium pyrophosphate disease (CPPD). Key points in gout and CPPD. Links. References. 38 Falls, Osteoporosis, Paget’s Disease and Osteomalacia (Harald J.J. Verhaar and Paul Jansen). Falls and osteoporosis. Paget’s disease. Osteomalacia. Key points. References. 39 Drugs and Falls (Nathalie van der Velde and Tischa J.M. van der Cammen). Introduction. Pathophysiology. Fall-risk-increasing drugs. Clinical approach. Treatment: drug withdrawal. Key points. References. 40 Pressure Ulcers (Rob J. van Marum). Introduction. The role of pressure in pressure ulcer development. The role of nutrition in pressure ulcer development. Risk assessment. Prevention. Local treatment. Key points. References. 41 Leg Ulceration (Gabrielle M. McMullin). Introduction. Aetiology. Symptoms and signs. Diagnosis. Therapy. Key points. Guidelines. References. 42 Xerosis and Asteatotic Eczema (Michael Yeung and Daniel Creamer). Xerosis. Actinic keratoses and Bowen’s disease. Bullous pemphigoid Candidiasis. Erysipelas and cellulitis. Contact dermatitis. Herpes zoster (shingles). Lichen planus. Malignant melanoma. Mycosis fungoides. Basal cell carcinoma and squamous cell carcinoma. Psoriasis. Scabies. Tinea. Urticaria and angio-oedema. Venous eczema and the dependency syndrome. 43 Age-Related Eye Diseases (Genevieve Larkin). Cataract. Glaucoma. Age related macular degeneration. Diabetic retinopathy. References. 44 Ear Disorders (Wynia Derks and Gerrit Hordijk). Introduction. Hearing loss. Tinnitus. External otitis. Drugs causing hearing problems. References. 45 Pain (Albert J.M. van Wijck). Introduction. Aetiology. Diagnosis. Therapy. Key points. References. 46 Palliative Care in the Elderly (Alexander de Graeff and Saskia Teunissen). Introduction. Symptoms. Palliative care in the elderly. Treatment of common symptoms in elderly patients. References. Index.

    10 in stock

    £110.95

  • The Management of Pain in Older People

    John Wiley & Sons Inc The Management of Pain in Older People

    Out of stock

    Book SynopsisThis book enables the reader to understand the principles underpinning the management of pain, with a particular emphasis upon the care of the older adult. The chapters explore concepts that are recognized to be involved in the pain experience.Trade Review"Provides the reader with a comprehensive review of the management of pain." (International Emergency Nursing, 2008) "Some of the case studies make interesting reading…" (Nursing Standard, January 2008)Table of ContentsChapter 1: Anatomy & Physiology of Pain. Pain & Sensation. Neural Pain Pathways. A Delta fibres. Dorsal Roots. Spinal cord to brain. Descending tracts & Substantia gelatinosa. The pain gate. Chronic pain. Peripheral sensitisation. Central Senstization. Older People. Chapter 2: Relating socio-economic issues with older people and pain: Independence dignity and choice. Health Economics. Cultural issues in older age. Resources linked with being older and in pain . Policy in health services, economics and older people. Diet and health in older age, related to economics. Independence. Dignity. Choice. Chapter 3: Creaking joints, a bit of arthritis, and aches and pains’: Older people’s experiences and perceptions of pain. The Study. Is pain different for older people Equating older age with aches and pains. Salience of older age linked to whether people experienced pain. Effect of pain on everyday lives. Managing the pain Keeping a positive attitude. Others in relation to pain. Implications for practice Exercises. Case studies. Mr Uddim. Violet Jones. Learning points. Chapter 4: Assessment of Pain. Visual Analogue Scale. Numerical Rating Scale. Verbal Descriptors. Faces Pain Scale. Colour Scale. McGill Pain Questionnaire (MPQ). Sensory Impairment. Learning disability. Cognitive impairment. Perception of Pain. Behavioural Pain Assessment Tools. DS DAT Scale. Checklist of non-verbal Pain Indicators (CNPI). ADD Protocol. DOLOPLUS Scale. The NOPAIN Scale. Pain Assessment Scale for Dementing Elderly (PADE). PAINAD. PACSLAC. Abbey Scale. Terminal Care. Chapter 5 : Communication. Research. Care workers and mentioning dementia. Explaining memory loss. Chapter 6: Acute versus Chronic Pain. Assessing Acute with Chronic Pain. Treatment for Acute with Treatment for Chronic. Opiophobia and Other Barriers. Chapter 7: Cancer Pain in the elderly in palliative care settings. How is cancer pain addressed in palliative care settings? The total pain concept - the patient experience. Multidimensional assessment. The family in palliative care. What are the issues for older people Expectations of pain in later life. Co-morbidity. Lack of access to specialist palliative care services. Compliance with pharmacological treatments. Age related alterations in drug disposition Management of cancer pain in the elderly in palliative care. Drugs compliance/concordance. Other treatments. Recommendations for practice Assessment and management Roles of MDT. SPCS intervention. Chapter 8: Care Settings. Problems with Chronic Pain in Older people. Physiological Changes. Getting used to pain. Assessment. Management. Education. Assets. Research Ongoing. Reluctance to report pain/ an acceptance that being in pain is normal and low expectations for help with medical interventions Age related perceptions of pain. Lack of Awareness of potential strategies for dealing with pain. Multidisciplinary Management. Cognitive Behavioural Therapy. Care Home Settings.

    Out of stock

    £44.96

  • The Old Age Psychiatry Handbook A Practical Guide

    John Wiley & Sons Inc The Old Age Psychiatry Handbook A Practical Guide

    15 in stock

    Book SynopsisThe Old Age Psychiatry Handbook provides a comprehensive but concise overview of psychiatric, medical and practical issues that may arise within the speciality. The book is written in an easy assimilated format, ideal for use in the clinic and on the ward.Trade Review"A practical guide to “coal-face” old age psychiatry. The book is packed with the kind of information it takes many years of practice to accumulate, and presents the information in a very easily digestible form. If the giants of old age psychiatry had told stories to trainees, this is what they would have told. It is clearly and concisely written." (International Journal of Geriatric Psychiatry, February 2009) "The book is written in an easy assimilated format, ideal for use in the clinic and on the ward." (Doody's, June 2008)Table of ContentsPreface. Acknowledgements. 1 The Assessment of Patients in Old Age Psychiatry. Introduction. Setting. The psychiatric history in older patients. The Mental State Examination (MSE). Assessing cognition with limited time. Assessment of everyday functioning. Physical examination. Investigations. Neuropsychiatric testing and the memory clinic. Assessment of carers. Summary. Further reading. 2 Dementia. Definition and diagnosis of dementia. Assessment of a patient with dementia. General management of dementia. Behavioural and psychological symptoms of dementia. Why differentiate between the dementias? Alzheimer’s disease. Vascular dementia. Dementia with Lewy bodies. Frontotemporal dementia. Less common causes of dementia. Mild cognitive impairment. Functional and molecular neuroimaging in dementia. Further reading. 3 Depression. Epidemiology. Clinical features and diagnosis. Risk factors for depression in old age. Treatment. Outcome. Prevention of depression in the elderly. Depression and dementia. Bereavement. Suicide. Further reading. 4 Bipolar Affective Disorder. Epidemiology. Aetiology. Clinical features and diagnosis. Management. 5 Anxiety Disorders and Obsessive Compulsive Disorder. Anxiety in the elderly. Generalised anxiety disorder. Panic disorder. Phobic disorders. Post-traumatic stress disorder. Other reactions to stress. Obsessive compulsive disorder. Further reading. 6 Psychotic Illness. Schizophrenia. Schizoaffective disorder. Delusional disorder. Further reading. 7 Personality Disorders. Personality. Personality and age. Definition and classification of personality disorders. Personality disorders in old age. Management of personality disorder in old age. Further reading. 8 Alcohol. Current guidelines for alcohol consumption. Definitions. Epidemiology. Detection and screening. Consequences. Management. Further reading. 9 Insomnia. Sleep architecture. Circadian rhythm. Insomnia and consequences in the elderly. Causes of insomnia. Assessment of a patient with insomnia. Non-pharmacological management. Pharmacological management. Further reading. 10 Psychopharmacology. Principles of drug treatment in old age psychiatry. Adherence. Pharmacokinetics and pharmacodynamics. Adverse drug reactions and interactions. Antidepressant drugs. Lithium. Anticonvulsant mood stabilisers. Antipsychotic drugs. Anxiolytics and hypnotics. Drugs used in dementia. Further reading. 11 Electroconvulsive Therapy. Indications. Mechanism of action. Efficacy. Adverse effects. Cautions. Consent. ECT and the Mental Health Act. Pre-ECT physical work-up. Medication and ECT. ECT procedure. Prevention of relapse. Further reading. 12 Psychological Therapies. Cognitive behavioural therapy. Behavioural therapy. Psychoanalytic psychotherapy. Further reading. 13 Practical, Legal and Social Issues. Provision of services. Legal issues in old age psychiatry. Social and financial issues in old age. Further reading. 14 Physical Illness and Old Age Psychiatry. Delirium. Vascular disease. Neurological disease. Rheumatological disease. Endocrinological disease. Nutritional deficit. Neoplastic disease. Palliative care. Further reading. Appendices. Index.

    15 in stock

    £49.46

  • BACE

    John Wiley & Sons Inc BACE

    Out of stock

    Book SynopsisThis book covers virtually all aspects of the rapidly developing field of beta secretase (BACE), from the original isolation and cloning of BACE, to the discovery of various classes of BACE inhibitors, to challenges in clinical development.Trade Review"Overall this book is a timely and comprehensive resource covering developments in BACE-targeted therapeutic agents from infancy to the present time. It will prove to be valuable to researchers working in the AD field, as well as to medicinal chemists seeking to learn more about rational design of aspartyl protease inhibitors." (ChemMedChem, November 2010) Table of ContentsPREFACE. ACKNOWLEDGMENTS. CONTRIBUTORS. CHAPTER 1 BACE, APP PROCESSING, AND SIGNAL TRANSDUCTION IN ALZHEIMER'S DISEASE (Dale E. Bredesen and Edward H. Koo). 1.1 Introduction. 1.2 BACE Cleavage of APP as a Molecular Switching Mechanism. 1.3 AD: An Imbalance in Cellular Dependence? 1.4 BACE Cleavage, Caspase Cleavage, and Neuronal Trophic Dependence. 1.5 BACE Cleavage of APP, Dependence Receptors, and Alzheimer Pathology. 1.6 Key Mutations Proximal of APP Processing to Aβ. 1.7 Final Remarks. CHAPTER 2 IDENTIFICATION OF BACE AS A TARGET IN ALZHEIMER'S DISEASE (Robert L. Heinrikson and Sukanto Sinha). 2.1 Introduction. 2.2 The Search for β-Secretase. 2.3 Validation of the BACE Target. 2.4 Final Remarks. CHAPTER 3 BACE BIOLOGICAL ASSAYS (Alfredo G. Tomasselli and Michael J. Bienkowski). 3.1 Introduction. 3.2 Clinical and Physiological Hallmarks of Alzheimer’s Disease (AD). 3.3 APP Processing. 3.4 Aspartyl Protease Classification. 3.5 BACE Structure. 3.6 Mechanism, Kinetics, Inhibition, and Specificity. 3.7 Assay Strategies for Inhibitor Finding and Development. 3.8 Common Assays Used to Identify and Study Inhibitors. 3.9 BACE Assays. 3.10 Final Remarks. CHAPTER 4 PEPTIDIC, PEPTIDOMIMETIC, AND HTS-DERIVED BACE INHIBITORS (James P. Beck and Dustin J. Mergott). 4.1 Introduction. 4.2 Elan/Pharmacia (Pfizer). 4.3 Oklahoma Medical Research Foundation (OMRF)/Multiple Collaborators. 4.4 Eli Lilly. 4.5 Merck. 4.6 GlaxoSmithKline. 4.7 Schering Plough. 4.8 Bristol-Myers Squibb. 4.9 Novartis. 4.10 Amgen. 4.11 Wyeth. 4.12 Final Remarks. CHAPTER 5 FRAGMENT-BASED APPROACHES FOR IDENTIFICATION OF BACE INHIBITORS (Andreas Kuglstatter and Michael Hennig). 5.1 Introduction. 5.2 Biophysical Methods Applied to BACE Fragment Screens. 5.3 BACE Inhibitors Identified by Fragment Screening. 5.4 Final Remarks. CHAPTER 6 STRUCTURE-BASED DESIGN OF BACE INHIBITORS: TECHNICAL AND PRACTICAL ASPECTS OF PREPARATION, 3-DIMENSIONAL STRUCTURE, AND COMPUTATIONAL ANALYSIS (Felix F. Vajdos, Veerabahu Shanmugasundaram, and Alfredo G. Tomasselli). 6.1 Introduction. 6.2 Preparation of BACE for Structural Studies. 6.3 Crystallographic Studies of BACE. 6.4 Structural Studies with BACE Inhibitors: Peptidomimetics and Nonpeptidomimetics. 6.5 Computational Approaches. 6.6 Final Remarks. CHAPTER 7 PHARMACOLOGICAL MODELS FOR PRECLINICAL TESTING: FROM MOUSE TO DOG TO NONHUMAN PRIMATES (Jason L. Eriksen, Michael Paul Murphy, and Elizabeth Head). 7.1 Introduction. 7.2 BACE1 and Mouse Models of AD. 7.3 Testing BACE Inhibitors in the Canine Model of Human Aging and AD. 7.4 BACE Inhibitors and Nonhuman Primates. 7.5 Final Remarks. CHAPTER 8 ADSORPTION, DISTRIBUTION, METABOLISM, EXCRETION (ADME), EFFICACY, AND TOXICOLOGY FOR BACE INHIBITORS (Ishrut Hussain and Emmanuel Demont). 8.1 Introduction. 8.2 Development of BACE Inhibitors with Optimized ADME Properties. 8.3 In Vivo Efficacy of BACE Inhibitors. 8.4 Toxicology of BACE Inhibitors. 8.5 Final Remarks. CHAPTER 9 CLINICAL TRIALS FOR DISEASE-MODIFYING DRUGS SUCH AS BACE INHIBITORS (Henry H. Hsu). 9.1 Introduction. 9.2 Update on Beta-Amyloid Therapies in Clinical Development. 9.3 Clinical Development of BACE Inhibitors and Other Disease-Modifying Drugs. 9.4 Final Remarks. CHAPTER 10 FUTURE STRATEGIES FOR DEVELOPMENT OF NOVEL BACE INHIBITORS: ANTI-APP β-SITE ANTIBODY AND APP BINDING SMALL MOLECULE APPROACHES FOR ALZHEIMER'S DISEASE (Beka Solomon, Michal Arbel-Ornath, Clare Peters-Libeu, and Varghese John). 10.1 Introduction. 10.2 β-Secretase: Discovery, Function, and Inhibitors. 10.3 Generation of Aβ Peptides via the Endocytic Pathway. 10.4 Generation of Anti-APP β-Site Antibodies. 10.5 Antibody Interference with Aβ Production in Cellular Model. 10.6 Antibody Interference with Aβ Production in Animal Models. 10.7 Identification of APP Binding Small Molecules that Block β-Site Cleavage of APP. 10.8 Final Remarks. AFTERWORD (Ruth Abraham). Introduction. Artwork as a Measure of the Progression of AD. INDEX.

    Out of stock

    £99.86

  • Elderly Care Medicine

    John Wiley and Sons Ltd Elderly Care Medicine

    Out of stock

    Book SynopsisElderly Care Medicine Lecture Notes provides all the necessary information, within one short volume, for a sound introduction to the particular characteristics and needs of elderly patients.Table of ContentsPreface vi Abbreviations vii 1 The world grows old 1 2 Health and social care for elderly people in the UK 11 3 Special features of medicine in the elderly 30 4 Old age psychiatry 44 5 Falls and immobility 63 6 Bones, joints and muscles 77 7 Stroke made simple 91 8 Other diseases of the nervous system 105 9 Cardiovascular disorders 119 10 Respiratory disease 137 11 Gastrointestinal disease and nutrition 148 12 Disorders of homeostasis and metabolism 169 13 Genitourinary disease 178 14 Blood and bone marrow 191 15 Eyes, ears, mouth and skin 203 16 Legal and ethical aspects of medical care of elderly people 220 17 Palliative care 231 Index 241

    Out of stock

    £29.40

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