Medical toxicology Books

Book SynopsisThe must-have health bible that explains exactly how to stay in radiant, optimal health all year round.Are you confused about what supplements you should be taking? Do you want to know how you can reverse the effects of pollution on your body? Would you like to eat seasonally?Drawing on Dr Jenny Goodman's 20+ years' experience as a medical doctor, lecturer and qualified nutritionist, Staying Alive in Toxic Times sets out exactly what to eat in order to live our healthiest lives, and how to adapt our lifestyle according to the season we are in.Dr Jenny Goodman lays out how to safely and effectively supplement your diet with vitamins and minerals, explains what really works in terms of detoxing your body, and sorts through the confusing myriad of diets and healthy eating fads, using her expertise to myth-bust. Staying Alive in Toxic Times also reveals how to avoid seasonal health hazards, such as indoor pollution, hay fever and SAD.With so many people feeling tired, ill and run-down, this timely guide is what everyone needs to read in order to live vibrant, happy and long lives.

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Book SynopsisNamed a ‘Best Book of the Year’ by Kirkus Reviews ‘Urgent and eye-opening, the book serves as a loud-and-clear alarm.’ – The Boston Globe From an MIT scientist, mounting evidence that the active ingredient in the world’s most commonly used weedkiller is contributing to skyrocketing rates of chronic disease. Glyphosate is the active ingredient in Roundup, the most commonly used weedkiller in the world. Over 300 million pounds of glyphosate-based herbicide are sprayed on farms – and food – every year. Agrochemical companies claim that glyphosate is safe for humans, animals and the environment. But emerging scientific research on glyphosate’s deadly disruption of the gut microbiome, its crippling effect on protein synthesis and its impact on the body’s ability to use and transport sulfur – not to mention several landmark legal cases – tells a very different story. In Toxic Legacy, senior research scientist Stephanie Seneff, PhD, delivers compelling evidence based on countless published, peer-reviewed studies – all in frank, illuminating and always accessible language. As Rachel Carson did with DDT in the 1960’s with Silent Spring, Seneff sounds the alarm on glyphosate, giving you guidance on simple changes you can make right now and essential information you need to protect your health, your family’s health and the planet on which we all depend. ‘A game-changer that we would be foolish to ignore.’ – Kirkus Reviews (starred) ‘Toxic Legacy will stand shoulder to shoulder with Rachel Carson’s Silent Spring. [This is] unquestionably, one of the most important books of our time.’ – David Perlmutter, MD, #1 New York Times bestselling author of Grain Brain ‘Dr. Seneff’s work will change the way we all think about food.’ – Mark Hyman, MD, New York Times bestselling authorTrade Review“Toxic Legacy is a bold and heroic work that reveals how today’s most well-respected science confirms the existential threat posed by the herbicide glyphosate. Dr. Seneff courageously defends her position in the face of seemingly insurmountable opposition from industry at every turn. And for this we owe her incalculable gratitude. Toxic Legacy will stand shoulder to shoulder with Rachel Carson’s Silent Spring, not just defining the pervasive threat to us and future generations, but more importantly, articulating what we can do right now to change our destiny. Unquestionably, one of the most important books of our time.”—David Perlmutter, MD, #1 New York Times bestselling author of Grain Brain and Brain Wash“A highly readable, fascinating look at how man-made chemicals invade the air we breathe, the water we drink, and the food we eat. Toxic Legacy is both a scientific exposé and an inspiring call to action. In revealing the diabolical mechanisms by which glyphosate damages human health, Dr. Seneff’s work will change the way we all think about food.”—Mark Hyman, MD, founder and director, The UltraWellness Center; Head of Strategy and Innovation, Cleveland Clinic Center for Functional Medicine; and a thirteen-time New York Times bestselling author“Anyone who wants to understand a root cause of the massive epidemics of chronic diseases we are experiencing—from autism to non-alcoholic fatty liver and 30+ other devastating diseases rampant in today’s society—can find the answers in Toxic Legacy. Dr. Seneff is to be complimented in her comprehensive, in-depth connection of the dots from glyphosate through the myriad biochemical and physiological processes altered, to the tragic consequences from the indiscriminate application of the Roundup and other glyphosate-based herbicides. The complex chemical perturbations are presented in an easily-understood manner, and the systems are well documented. Her ‘relaxed’ writing style makes for easy reading and ready comprehension of this important information.”—Don M. Huber, professor emeritus, Purdue University and retired colonel, US Army, Medical Intel“Dr. Seneff is a senior scientist at MIT. She not only understands molecular biology at a deep level but also has the unique ability to translate extremely complex technical concepts into easy-to-understand language. This is a must-read book to help you comprehend one of the most significant toxic threats unleashed on the world. Toxic Legacy is the modern-day equivalent of Rachel Carson’s Silent Spring from 1962—one of the greatest science books of all time.”—Dr. Joseph Mercola, founder, mercola.com, the most visited natural health site for eighteen years“Monsanto knew for decades that glyphosate causes cancer and a deadly retinue of other devastating illnesses. Instead of warning its customers and consumers about those risks, Monsanto manipulated the science, defrauded regulators, bribed prominent researchers, transformed the EPA pesticide division into a cesspool of corruption, and promoted propaganda worldwide, systematically lying to the public that the deadly pesticide was safe. This company injured public health, destroyed our soils, exterminated species, wiped out small farmers, and deprived the public of their fundamental civil right of informed consent. Monsanto made a special project of discrediting and destroying scientists, advocates, and reformers who exposed its corrupt cover-up. Among the most prominent of these was heroic MIT researcher Dr. Stephanie Seneff. In 2018, I was fortunate enough to be a part of the legal team that finally brought Monsanto to justice. We relied heavily on Dr. Seneff’s research to achieve this victory.”—Robert F. Kennedy, Jr.“Glyphosate (the active ingredient in Roundup) and the other toxic chemicals and GMOs of industrial agriculture are the primary drivers of the chronic disease epidemic that has degenerated public health and the environment. Until we drive these poisons off the market and make the transition to organic and regenerative farming practices, our health, the health of our children, and the health of the planet are at risk. Glyphosate is the DDT of the twenty-first century, and Toxic Legacy is essential reading for everyone who cares about food and health.”—Ronnie Cummins, Organic Consumers Association; author of Grassroots Rising“Seneff takes us on a shocking biochemical journey through the deleterious effects of glyphosate on the environment and humans. The author clearly explains the ever-growing body of scientific evidence of the insidious consequences of its continued, massive application across the world. As Seneff shows, the herbicide is the common denominator to a swath of environmental and human health problems, from obesity to autism to toad die-offs. The herbicide disrupts the uptake of minerals by plants and kills the bacteria, fungi, and other organisms that have symbiotic relationships with plants for mutual health. The direct effect on humans is dire, as glyphosate damages the gut microorganisms our bodies use to synthesize the amino acids that build body proteins. This affects everything from liver and kidney functions to fertility and autoimmunity. Seneff is precise about the biochemistry involved, but she is a genial, attentive guide. “I know this is technical but stay with me,” she writes. When she ventures into new, even controversial work, she is diligent in her analysis but candid about such territory: ‘I propose . . . ,’ ‘may be damaging . . . ,’ ‘Autism is not due to glyphosate exposure alone. . . .’ The two most salient—and devastating—points that Seneff highlights: First, glyphosate, which shows up in our soil, water, and even air, is disturbingly pervasive . . . ubiquitous . . . ‘nearly impossible for even the most diligent person to avoid.’ Second, the agricultural industry, taking a page from the tobacco industry’s playbook, does everything it can to hide the dangers: Monsanto and other companies censor research and proliferate junk science, raking in profits by turning a blind eye to the chronic illnesses resulting from glyphosate use. Comparisons will be made to Rachel Carson’s Silent Spring—and they should be. We can only hope Seneff’s work goes on to rival Carson’s in reach and impact.”—Kirkus Reviews (starred)“At last, a scientist with impeccable credentials has painstakingly assembled, categorized, and presented the growing body of evidence that highlights the negative impacts of the most widely used pesticide in the world. “Stephanie’s forensic analysis demonstrates beyond reasonable doubt that the use of Roundup and its active ingredient glyphosate is not only poisoning the planet but also its human population. “Everyone should read this book. It’s about our future health and the health of the planet. What issue could be more important than that? As an organization that has been highlighting these potential harms for more than a decade, The Sustainable Food Trust hopes that this milestone publication gets the publicity it needs and deserves.”—Patrick Holden, founder and chief executive, Sustainable Food Trust“Stephanie Seneff’s Toxic Legacy continues on the path laid by Rachel Carson in Silent Spring. Seneff provides the scientific evidence of how, by disrupting our bodies’ metabolic pathways, glyphosate is at the root of multiple metabolic, neurological, autoimmune diseases that have taken epidemic form. More significantly, Seneff’s book introduces us to the complex, sophisticated, metabolic processes of life, from the soil to our gut microbiome. It is a book for governments who want to ban glyphosate. It is a book for every citizen who seeks to regenerate the health of the planet and people.”—Dr. Vandana Shiva, director, Navdanya; coauthor of Oneness vs. the 1%“There is nothing more important than the health of our current and future generations. There is nothing more costly than jeopardizing the physical and mental health of generations of our populations. Without our health, we cannot effectively combat climate change, homelessness, poverty, racial injustice, addiction, or other daunting issues. This book unlocks why we should and how we can resolve a myriad of skyrocketing health issues plaguing society. If heeded, the result of banning glyphosate would put us in the direction of recovering our health and the future of human life on this planet.”—Zen Honeycutt, founding executive director, Moms Across America“Dr. Stephanie Seneff, established and out-of-the-box critical thinker/researcher, lays down the foundation of our understanding of the toxicity from glyphosate, in a clear and concise format, from the practical to the molecular mechanisms on how glyphosate does harm. Although Dr. Seneff leans heavily on the biochemical basis of glyphosate’s modes of action, her information is understandable and carefully cited for the more investigative readers. She carefully describes the blueprint for the myriad of chronic diseases now prevalent globally and how they are created around the ubiquitous glyphosate. Her book is not only an analytic reference treasure, but a call to action to denounce and reverse our self-imposed toxic legacy.”—Michelle Perro, MD; coauthor of What’s Making our Children Sick?; executive director and cofounder, GMO Science“While I’d always intuited that glyphosate exposure—with all of its other deleterious effects—is a contributor to the stark rise in autoimmunity, Dr. Seneff presents unequivocal evidence of this truth.”—Jill McLaughlin (Grunewald), HNC, FMCHC, bestselling author of The Essential Thyroid Cookbook“I’ve long been impressed with Dr. Stephanie Seneff’s published work on neurological damage, environmental toxins, and chronic disease. She’s a brave and meticulous scientific researcher. She’s also one of the smartest people I know.”—Paul Thomas, MD, #1 Amazon bestselling author of The Vaccine-Friendly Plan and The Addiction Spectrum“For the last decade, while ‘science’ and ‘health’ journalists were gleefully content to repeat the limited corporate talking points about glyphosate’s safety, Dr. Seneff was on the hunt for deeper truths. Toxic Legacy may be one of the most important literary journeys, weaving in a bounty of irrefutable evidence, essential science, and the personal journey of one of the most treasured scientific researchers of our time.”—Jefferey Jaxen, investigative health reporter“Stephanie Seneff is one of the most important, original, and brilliant scientific researchers of our time.”—Jennifer Margulis, PhD, award-winning journalist and author “Dr. Stephanie Seneff’s deep dive into the science of glyphosate helps us as consumers make choices that protect ourselves, our families, and the environment.”—Kate Hanley, author of How to Be a Better Person and host, How to Be a Better Person podcast“Glyphosate has become a bit like sugar, used by everyone for everything, everywhere. It has spread, largely invisibly, across farms and gardens and parks and so, too, into our food, bodies, and lives. This book lays out, in expert technical detail by a scientist with huge and broad knowledge, what this ubiquitous and ‘uniquely diabolical’ chemical and its formulations could be doing. And how the deeply worrying, chronic consequences this may have for our health are only being recognized—from affecting our critically important gut microbes to causing hormone disruption and DNA damage. It’s also an intriguing, if complex, lesson on the dense web of interconnected bodily functions, structures, enzymes, and chemicals. Glyphosate has also allowed a kind of sterilization of farming with even wider consequences for the ecosystems on which we all depend. Dr. Seneff shows clearly how we need to act fast to curb its use and so change our diets, our green spaces, and how we farm.”—Vicki Hird, MSc, FRES, food and environmental writer and campaigner; author of Rebugging the Planet “I am so thankful for Stephanie Seneff’s work, which is invaluable in protecting the health of generations to come. I did a toxin screen on my three children a few years back and found they were all high in glyphosate even though we used organic products for our home and garden and tried our best to eat organic food! Dr. Seneff’s work is spreading much-needed awareness so our children and our children’s children can grow up less toxic.”—Cammy Benton, MD, founder, Benton Integrative Medicine“It’s crucial we all understand the harm environmental toxins are doing to people and the planet. Like Rachel Carson who blew the whistle in her book Silent Spring, Stephanie Seneff is educating us about current poisons. There’s no question in my mind that she is the scientist to help us open our eyes.”—Vera Sharav, president, Alliance for Human Research Protection and Holocaust survivor

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Book SynopsisShortlisted for the BMA Book Awards and Macavity Awards 2016Fourteen novels. Fourteen poisons. Just because it''s fiction doesn't mean it''s all made-up ...Agatha Christie revelled in the use of poison to kill off unfortunate victims in her books; indeed, she employed it more than any other murder method, with the poison itself often being a central part of the novel. Her choice of deadly substances was far from random the characteristics of each often provide vital clues to the discovery of the murderer. With gunshots or stabbings the cause of death is obvious, but this is not the case with poisons. How is it that some compounds prove so deadly, and in such tiny amounts?Christie''s extensive chemical knowledge provides the backdrop for A is for Arsenic, in which Kathryn Harkup investigates the poisons used by the murderer in fourteen classic Agatha Christie mysteries. It looks at why certain chemicals kill, how they interact with the boTrade ReviewA is for Arsenic: The Poisons of Agatha Christie has lethal charm. Harkup leads every chapter with a literary quote, then proceeds to tell us what the poison is, how and under what circumstances it kills, some real-life instances of its use and what role it plays in the Christie plot ... good fun. * The Washington Post *This book is fascinating, and anyone who is interested in the myriad painful and unpleasant ways in which people can be killed will relish it. * The Times *Harkup superbly captures the texture of Christie's books, the sunshine and the surreptitious villainy. * Daily Mail *A cracking compendium of Christie's poisonings ... A Is For Arsenic will appeal to any fan of Christie's work, but as a potted history of poisons, antidotes and medicines it has much wider reach than that. * BBC Focus *Fact and fun packed, A is for Arsenic looks at why certain chemicals kill, how they interact with th body, and the feasibility of obtaining, administering and detecting these poisons. * Agatha Christie Website *An enjoyable, alphabetical overview of the renowned mystery writer's frequent weapon of choice. * Washington Independent Review of Books *A knockout analysis of poisons used in Christie's novels and short stories … Each chapter gives riveting information on the poison's chemical makeup, how it kills, whether there's an antidote, its history and its use in Christie's works and in real life ... This is an absolutely bravura chemical compound. * Booklist *If you are coming to Agatha Christie's work for the first time, an avid fan, have an interest in crime or toxicology, or just like being taken on an adventure through time, A is for Arsenic is a must read. * Chemistry World *A killing read that combines scientific expertise with fan-based knowledge. * Saga *Table of Contents1. Dame Agatha’s Deadly Dispensary 2. A is for Arsenic – Murder is Easy 3. B is for Belladonna – The Labours of Hercules 4. C is for Cyanide – Sparkling Cyanide 5. D is for Digitalis – Appointment with Death 6. E is for Eserine – Crooked House 7. H is for Hemlock – Five Little Pigs 8. M is for Monkshood – 4:50 from Paddington 9. N is for Nicotine – Three Act Tragedy 10. O is for Opium – Sad Cypress 11. P is for Phosphorus – Dumb Witness 12. R is for Ricin – Partners in Crime 13. S is for Strychnine – The Mysterious Affair at Styles 14. T is for Thallium – The Pale Horse 15. V is for Veranol – Lord Edgware Dies Appendix Glossary Bibliography

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Book SynopsisTrade ReviewFrom customer reviews of the previous edition: 2018 BMA Awards: Winner, Internal Medicine "This book is amazing helpful. It goes through every core condition you need and is simply written and to the point but has all the information that is needed. As a medical student this book has been great for my studies" "Great book, small enough to take on the wards, full of information on the go. I love it." "Excellent little companion book." "Good book. It has all the basics that student needs to revise, write assignments etc"Table of Contents1 Ethics and Communication 2 Infectious Diseases 3 Gastroenterology and Nutrition 4 Liver, Biliary Tract, and Pancreatic Disease 5 Haematological Disease 6 Malignant Disease 7 Rheumatology 8 Water, Electrolytes, and Acid-Base Balance 9 Renal Disease 10 Cardiovascular Disease 11 Respiratory Disease 12 Critical Care Medicine 13 Clinical Pharmacology and Toxicology 14 Endocrine Disease 15 Diabetes Mellitus and Other Disorders of Metabolism 16 The Special Senses 17 Neurology 18 Dermatology 19 Elderly Medicine and Frailty

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Book SynopsisThis second edition of Clarke's Analytical Forensic Toxicology offers a fresh perspective on the drugs and poisons that you are most likely to encounter in forensic toxicology, with a focus on collection, extraction and analysis.Trade Review"...a useful reference for students both undergraduate and postgraduate, as well as toxicologists who are relatively new to this discipline...There are many chapters from experienced toxicologists (many who are familiar to us) and the book is well structured and follows a consistent approach to understanding the essentials of forensic toxicology...There is a comprehensive number of chapters on techniques (extraction and analysis) and the major chromatographic approaches are covered well by recognised authors with considerable expertise...So if you have the 4th edition of Clarke's Analysis of Drugs and Poisons would you also buy this volume as well? Yes I would because the book is geared to a more novice readership - students, researchers and inexperienced toxicologists." Dimitri Gerostamoulos, TIAFT Bulletin 43(2), July 2013. -- Dimitri Gerostamoulos * TIAFT Bulletin *"This new edition is based on content in volume 1 of Clarke's Analysis of Drugs and Poisons, and modified for student use...this volume is full of useful information that will allow students to become familiar with the field. Summing up: Recommended. Upper-division undergraduates and graduate students." J. Allison, The College of New Jersey, CHOICE (51:3) November 2013. -- J. Allison * CHOICE *Table of Contents1. Introduction to Forensic Toxicology 2. Pharmacokinetics and Metabolism 3. Drugs of Abuse 4. Other Poisons 5. Workplace Drug Testing 6. Alternative Specimens 7. Postmortem Toxicology 8. Clinical Toxicology 9. Drug Abuse in Sport 10. Drug-Facilitated Sexual Assault 11. Alcohol, Drugs and Driving 12. Forensic Chemistry & Solid Dosage Form Identification 13. Sampling, Storage and Stability 14. Extraction 15. Colour Tests and Thin-Layer Chromatography 16. Immunoassays 17. Ultraviolet, Visible and Fluorescence Spectrophotometry 18. Infrared Spectroscopy 19. Gas Chromatography 20. High-Performance Liquid Chromatography 21. Mass Spectrometry 22. Quality Control and Assessment

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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Book SynopsisTable of ContentsI. Oxidative Stress and Disease 1. Oxidative stress causes 2. Historical perspective 3. Chemicals and chemical mixtures 4. Particles and fibers 5. Air pollution 6. Alcohol, tobacco and recreational drug use 7. Radiation 8. Chronic inflammation 9. Chronic Trauma 10. Dietary choices 11. Sleep deprivation 12. Hot and cold Environmental temperature extremes 13. Pre-existing disease 14. Pharmaceutical drugs 15. Chronic psychological stress 16. Genetic and epigenetic factors II. Mechanism of Disease Onset 17. Disease hallmarks and biomarkers 18. Disease clusters 19. Disease co-morbidities 20. Free radical attack on DA 21. Free radical attack on proteins 22. Free radical attack on lipophilic cell membranes 23. Free radical stability factors 24. Free radical attack on mitochondria and energy production 25. Immune System role 26. Obesity-oxidative stress-disease triangle: Impact of obesity oxidative stress and disease 27. Acute versus chronic oxidative stress 28. Age and late onset disease 29. Total oxidative stress III. Oxidative Stress Index and Its Applications 30. Oxidative stress index and its premise 31. Predicting likelihood of disease onset 32. Identifying primary causes of specific diseases 33. Oxidative Stress Index as a public health survey instrument 34. Adverse drug reaction prediction 35. Predicting severity of COVID-19 and other diseases 36. Oxidative Stress Index as a virtual diagnostic tool 37. Disease prevention 38. Future applications

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Book SynopsisForensic professionals, particularly medical examinersâoften working through heavy caseloadsârequire quick and easy access to reliable sources of information to help interpret toxicology results. While several in-depth resources are available, they are often large, cumbersome, and contain more information than is often needed. The Handbook of Forensic Toxicology for Medical Examiners is a concise handbook referencing the most common toxic substances and their reported non-toxic, toxic, and lethal concentrations, making it an ideal text for quick reference in the lab or autopsy room.Features of the Second Edition: Explains the principles of postmortem toxicology and the factors which must be considered Provides tables of toxicologic data for over 200 commonly encountered substances, including drugs of abuse, poisons, prescription drugs, and over-the-counter medications Includes discussion andTable of ContentsList of Abbreviations 1. How to Use This Book 2. Special Drug Groups 3. Specific Drugs (Alphabetical Listing) Appendix A. Specimen Types and Collection Appendix B. Common Methodologies Appendix C. Normal Values Reference Charts Appendix D. Conversion Chart

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Book SynopsisAs with the previous editions, Introduction to Toxicology, Fourth Edition, continues to chart the evolution of the field of toxicology, from the use of natural toxins by ancient tribes through the developments established by Paracelsus, and progresses through to the current topics in the public interest. For centuries, the study of toxicology has fascinated students. The book begins with basic toxicological principles, including an historical summary, dose-response relationships (NEW chapter), exposure-response relationships (NEW chapter), disposition, and metabolism of xenobiotic toxic substances. Other important new chapters include target organ toxicity, toxicity of carcinogenic agents and new and updated concepts in toxicity testing, and antidotes and treatment of poisonings. In all, nine new or expanded chapters from the third edition are advanced.Current concerns about the effects of therapeutic drugs, carcinogens, industrial toxins, pesticides, and herbicides onTable of Contents1. Introduction. 2. Dose-Response Relationship. 3. Exposure-Response Relationship. 4. Disposition of Toxic Compounds. 5. Metabolism of Xenobiotic Compounds. 6. Target Organ Toxicity. 7. Carcinogenic and Mutagenic Compounds. 8. Drugs as Toxic Substances. 9. Industry Toxicology. 10. Food Additives and Contaminants. 11. Pesticides and Herbicides. 12. Environmental Pollutants. 13. Natural Products. 14. Commercial and Domestic Products. 15. Fundamentals of Toxicity Testing. 16. Risk Assessment. 17. Antidotes and Treatment of Poisoning. Answers to Chapter Questions. Glossary.

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Book SynopsisEnvironmental issues such as ozone layer depletion, overpopulation, biodiversity loss, global warming, natural resource depletion, and so on affect every organism on the planet somehow. Environmental biotechnology applications can help to protect and restore the quality of the environment. The goal is to use biotechnology with other technologies and safety procedures to prevent, arrest, and reverse environmental degradation. Environmental biotechnology is one of the most rapidly expanding and practically useful scientific fields. Biochemistry, physiology and genetic research of microorganisms can be converted into commercially available technologies for reversing and preventing further deterioration of the earth''s environment. Solid, liquid, and gaseous wastes can be altered either by recycling new by-products or by purifying to make the end product less harmful to the environment. Biotechnology for Toxic Remediation and Environmental Sustainability discusses the remoTable of ContentsPreface. About the Editors. List of Contributors. Recent Literature on Biosorption as a Sustainable Environmental Technology to Remove Pollutants. Production of Biofuels and Value-Added Products Using Anaerobic Digestion of Wastewater. Biodiesel Production by Organic Transformations. An Overview of Green Corrosion Inhibitors. Biochemical, Molecular, and Microbial Ecological Aspects of Bioelectrochemical Systems. Food Microbiome: Ecology, Functions, and Emerging Trends in Food Safety and Security. What We Know and What We Don’t on Antimicrobial Resistance: A Call for Action. Overall Thymoquinone Pharmacological Properties and Its Use as an Anticancer Agent. Function of ZnS Nanoparticles on Stress-Mediated Apoptosis in Mouse Retinal Pigment Epithelial Cells. Index.

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Book SynopsisIn the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology and classic human toxicology, Mixture Toxicity: Linking Approaches from Ecological and Human Toxicology incorporates extensive reviews of exposure to toxicants, toxicokinetics and toxicodynamics, toxicity of mixtures, and risk assessment.The book examines developments in both fields, compares and contrasts their current state of the art, and identifies where one field can learn from the other. Each chapter provides an essential overview of the state of the art in both human and ecotoxicological mixture risk assessment, focusing on the work published in the last fifteen years. The coverage progresses from exposuTable of ContentsExposure. Introduction. Emission Scenarios. Interactions Affecting Availability and Exposure to Chemical Mixtures. Environmental Fate Modeling. Exposure Scenarios and Monitoring. Summary and Conclusions. Toxicokinetics and Toxicodynamics. Introduction. Fundamental Principles. Toxicokinetics. Toxicodynamics. Toxicity from Combined Exposure to Chemicals. Introduction. Approaches to Mixture Effect Assessment. Mechanisms and mixture effects. The predictability of mixture effects – a brief review. Defining Determinants of Synergistic Mixture Effects. Mixture Effects at Low Levels. What About the Real World? Test Design, Mixture Characterization and Data Evaluation. Introduction. Testing Aims. Concentration Addition and Independent Action: Empirical Modeling. Technical Issues and Pitfalls. Component-Based Approaches, Test Designs and Methods. Whole Mixture Approaches, Test Designs and Methods. Case Studies. Risk Assessment. Introduction. Typical Features of Mixture Assessment. State of the Art in Mixture Assessment. Conceptual Framework for Human and Ecological Risk Assessment of Mixtures. Issues in Human and Ecological Risk Assessment of Mixtures. Appendix. Glossary.

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Book SynopsisDangerous, dark and difficult to detect, poisons have been a common character in literature from ancient times to the modern day. Their ability to perform deadly deeds at a distance is a common device for creating dramatic tension and playing on our real life fears. But what is fact and what is pure fiction? From Shakespeare and Dickens to Hugo and Poe, the macabre world of literary poisonings is as large as it is fascinating. Utilising real forensic science Poisonous Tales explores the real science inspiring the toxins and tinctures in our favourite works. Could a poison really mimic death in Romeo and Juliet? What is the cause of the mad Hatter’s malady in Alice in Wonderland? And could a stone from the stomach of a goat really have been used as an antidote in Harry Potter and the Half-Blood Prince? Through these and many more ‘cases’ we discover the captivating truth in the texts and how real-life tragedies can replicate themselves in fiction.Table of ContentsUseful Herb or Dreadful Poison;The Cry of Death;A Ghostly Encounter with Poison;The Flattering Truth of Sleep;The Queen of Poisons;Outfoxed by Digitalis;Poison for a Broken Heart;The Power to Heal as well as Harm;Beautiful but Deadly;Nature’s Toxic Gift;Mad as a Hatter;The Silent Killer

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Book SynopsisHuman biomonitoring has developed from a research tool in occupational and environmental health to identify and quantify exposures to harmful substances in urine and blood. The analytical methods for detection of substances in biological media have considerably improved with smaller detection limits and more precise and specific measurements. Human biomonitoring is a valuable tool in exposure estimation of selected populations and currently used in surveillance programs all over the world. This two volume set provides an overview of current available biomarkers and human biomonitoring programs in environmental health, which is timely given the present debate on adverse health effects from environmental exposures. The books decribe both previous and ongoing studies as well as the newer biomarkers of exposure and effects. Volume one describes current human biomonitoring programs in Germany, Romania, France, Canada, India and Belgium, providing convincing evidence of a global decline in human exposures to lead and increasing concern from exposure to endocrine disruptors and the genotoxic compound. Biomarkers of specific exposures to a wide range of widely used everyday compounds such as phthalates, PFCs, bisphenol A, brominated flame retardants, PAHs, dioxins, mercury and arsenic are also discussed. Volume two decribes human biomonitoing of exposures to environmental tobacco smoke, mycotoxins, physiological stress, hormone activity, oxidative stress and ionizing radiation, as well as effect biomarkers of hemoglobin adducts, germ cells, micronuclei and individual susceptability. The books will be essential reading for toxicologists, environmental scientists and all those working in the safety and risk assessment of chemicals.Table of ContentsBiomarkers of exposure - Hemoglobin adducts; Biomarkers of human exposure to environmental tobacco smoke (ETS); Biomarkers of exposure û mycotoxins: aflatoxin, deoxynivalenol and fumonisins; Biological measures and the psychosocial working environment; Micronuclei for human biomonitering; Biomarkers of individual susceptibility: genetic polymorphisms and their interplay with micronucleus frequencies Biomarker of effects on hormone functions; Biomarkers of Exposure - Oxidative Stress to DNA and Lipids û Relation to Air Pollution; Male and female germ cell biomarkers Biomarkers of exposure and effect: ionizing radiation; Ethics and data protection in human biomarker studies

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Book SynopsisPopular among students and clinicians for its easy-to-read, case-study format, Winter’s Basic Clinical Pharmacokinetics, 7th Edition, clarifies complex concepts to help you confidently apply pharmacokinetics and therapeutic drug monitoring to patient care. This straightforward text is divided into two parts, reviewing basic pharmacokinetic principles in Part I and illustrating the clinical application of these principles to the most commonly encountered problems in Part II. The significantly updated and expanded 7th Edition adds essential coverage of the use of pharmacokinetics in managing obesity, pregnancy, as well as anticoagulation. NEW! Chapters unique to this 7th Edition equip students with proven pharmacokinetic approaches to obesity, pregnancy, and anticoagulation. Straightforward two-part format reinforces fundamental concepts and related clinical applications to ensure an advanced-level mastery. Case-based approach, similar to Applied Therapeutics, cultivates essential clinical reasoning capabilities. Detailed drug monographs familiarize students with the most commonly prescribed drugs for a wide range of problems and conditions.

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Book SynopsisCovering areas of drug toxicity which address the major issues including registration requirements of new drugs and pharmacovigilance, this book provides an overview of the methodology and requirements of pre-clinical safety assessment of new medicines. It discusses mechanisms by which drugs cause toxic effects in living organisms.Trade Review'The text is well written, concise and easy to understand with informative and helpful illustrations, figures and tables...it serves as an excellent companion to pharmacology textbooks, dealing with the issues relevant for assessing the safety of new drugs...a good starting point for the novice toxicologist, ambitious undergraduate student or graduate students working in the pharmaceutical sciences.' Irish Pharmacy Journal, November 2006, p418 * Irish Pharmacy Journal *'...this is a great little book...the text is aimed primarily at new PHD students in the pharmaceutical and related sciences but could equally well serve taught postgraduate students on toxicology, clinical pharmacology, drug development and safety or similar courses. The book 'does exactly what it says on the tin' and will definitely whet the appetite of enthusiastic young researchers for toxicology.' Heather M Wallace, Summer 2007 issue of the British Toxicology Society Newsletter -- Heather M Wallace * British Toxicology Society Newsletter *Table of Contents1. General toxicology; 2. Drug metabolism: inactivation and bioactivation of xenobioptics; 3. Molecular and cellular mechanisms of toxicity; 4. Teratology; 5. Genotoxicity; 6. Carcinogenicity of drugs; 7. Liver toxicity; 8. Kidney toxicity; 9. Toxicology in the respiratory system; 10. Immunotoxicity; 11. Clinical toxicology; 12. Safety assessment of pharmaceuticals: regulatory aspects; 13. Pharmacovigilance.

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Book SynopsisAn essential, 2-volume reference for everyone interested in herpetology—professional herpetologists and their students conducting research in the classroom, at the zoo, and in the field, as well as amateurs.Trade ReviewThe discussion of envenomation identification, grading, and treatment is fascinating and clinically valuable. I was very impressed with the organization and readability of the text. I nearly forgot to mention the wonderful color photographs.... The amount of information packed into these two volumes is truly mindboggling. This is a 'must have' reference for anyone interested in these creatures. -- Grady Calhoun * "The Forked Tongue," The Monthly Newsletter of the Greater Cincinnati Herpetological Society *The information available is overwhelming, yet it is presented in scholarly and clearly understandable fashion, utilizing every available form of still documentation.... The two volumes are indeed a masterful compilation and overview of the venomous reptiles in this geographic region. The volumes are well-produced and published, with sturdy binding, easily readable font size and style, and excellent quality printing of illustrations, colored figures, and the abundant colored photographic plates.... The chapter on 'Venom Poisoning by North American Reptiles' and the following contribution entitled 'Snake Bites in Central and South America: Epidemiology Clinical Features and Clinical Management' offers abundant experiences, observations, and recommendations that often support those currently used by toxicologists and emergency room physicians in North America, yet are diverse enough to highlight some of the controversies and continuing debates on what is most appropriate when and how!... One could easily spend many hours reviewing the clinical recommendations made and observing the excellent documented color photographs of effects and the good-and-bad results from various management procedures.... Just to skim through the illustrations and accompanying text for elaboration opens up a new world for students, herpetologists, zoologists, and veterinary and human toxicologists conducting research in the field or at the zoo, or managing envenomated patients. * Veterinary and Human Toxicology *

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Book SynopsisThe outbreak of the “Minamata Disease” in 1950s Japan remains one of the most horrific examples of environmental poisoning in history. Based on primary documents and interviews, this book describes responses to this incidence of mercury poisoning, focusing on the efforts of its victims and their supporters to secure redress.Trade ReviewThis is the first account, in any language, which covers the controversies surrounding the infamous mercury poisoning in Minamata in southern Kyushu over the time frame of ninety years, from the founding of the factory which caused the pollution, up to the settlement for compensation reached in 1995… George’s monograph provides an excellent point of departure for further inquiries. -- Anja Osiander * Social Science Journal *

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Book SynopsisDerived from the definitive guide to medical toxicology, this hands-on companion provides accurate information for diagnosing and treating poisoned patients on the spotA Doody's Core Title for 2024!After more than a decade on the market, Goldfrankâs Toxicologic Emergencies has established itself as the go-to reference for medical toxicologyâand this companion manual distills the most important information into a portable, easy-to-navigate resource.Goldfrankâs Manual of Toxicologic Emergencies distills critical information into short summaries and synopses, so you can use it to treat patients in clinical settings or for quick review of critical topics. Fully updated to ensure all information is completely current, this new edition is filled with tables, figures, images, and other visuals to make finding the right answers quick and easy. Each chapter is a direct distillation of the corresponding chapter in Goldfrankâs Toxicologic EmeTable of ContentsThe table of contents (below) will mirror the main text, both for completeness and ease of cross-referencing. Historical Principles and Perspectives Toxicologic Misfortunes and Catastrophes in History PART A THE GENERAL APPROACH TO THE PATIENT Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes Principles of Managing the Acutely Poisoned or Overdosed Patient SC1. Principles of Antidote Stocking Decontamination Principles: Prevention of Gastrointestinal Absorption SC2. Decontamination Principles: Prevention of Dermal, ophthalmic and inhalational Absorption A1. Activated Charcoal A2. Whole-Bowel Irrigation and Other Intestinal Evacuants Principles and Techniques Applied to Enhance Elimination Laboratory Principles Principles of Diagnostic Imaging Pharmacokinetic and Toxicokinetic Principles PART B THE FUNDAMENTAL PRINCIPLES OF MEDICALTOXICOLOGY SECTION I BIOCHEMICAL AND MOLECULAR CONCEPTS Chemical Principles Biochemical and Metabolic Principles Fluid, Electrolyte, and Acid–Base Principles Neurotransmitters and Neuromodulators Withdrawal Principles SECTION IIPATHOPHYSIOLOGIC BASIS: ORGAN SYSTEMS Cardiologic Principles I: Electrophysiologic and Electrocardiographic Principles Cardiologic Principles II: Hemodynamics Dermatologic Principles SC3. Transdermal Toxicology Gastrointestinal Principles Genitourinary Principles Hematologic Principles Hepatic Principles Neurologic Principles Oncologic Principles Ophthalmic Principles Otolaryngologic Principles Psychiatric Principles SC4. patient violence Respiratory Principles Thermoregulatory Principles SECTION IIISPECIAL POPULATIONS Reproductive and Perinatal Principles Pediatric Principles Geriatric Principles PART C THE CLINICAL BASIS OF MEDICAL TOXICOLOGY SECTION I A. ANALGESICS AND ANTIINFLAMMATORY MEDICATIONS Acetaminophen A3. N-Acetylcysteine Colchicine, Podophyllin, and the Vinca Alkaloids Nonsteroidal Antiinflammatory Drugs Opioids A4. Opioid antagonists SC5. Internal Concealment of Xenobiotics SC6. Harm Reduction for Opioid Overdose Salicylates A5. Sodium bicarbonate B. Food, Diet, and Nutrition Botulism A6. botulinum antitoxin Food Poisoning Dieting Xenobiotics and Regimens Athletic Performance Enhancers Essential Oils Plantand Animal-Derived Dietary Supplements Vitamins Iron A7. deferoxamineC. pharmaceuticals Pharmaceutical Additives Antidiabetics and Hypoglycemics/Antiglycemics A8. Dextrose(d-Glucose) A9. octreotide Antiepileptics A10. l-carnitine Antihistamines and Decongestants A11. physostigmine salicylate Chemotherapeutics Methotrexate,5-Flourouracil, and Capecitabine A12. folates :leucovorin (Folinic acid) and Folic Acid A13. glucarpidase(carboxypeptidase g2) A14. uridine triacetate SC7. Inadvertent Intrathecal Administration of Xenobiotics SC8. Extravasation of Chemotherapeutics Antimigraine Medications Thyroidand Antithyroid Medications D. Antimicrobials Antibacterials, Antifungals, and Antivirals Antimalarials Antituberculous Medications A15. pyridoxine E. Cardiopulmonary Medications CASE STUDY 4 Antidysrhythmics A16. Magnesium Sulfate Antithrombotics A17. Protein Complex Concentrate and Novel Antithrombotic Antidotes A18. Vitamin k1 A19. protamine β-Adrenergic Antagonists A20. Glucagon

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Book SynopsisTable of ContentsSection I: Principles of Pharmacology Chapter 1 Introduction to Pharmacology Chapter 2 Pharmacokinetics Chapter 3 Pharmacodynamics Chapter 4 Drug Development and Safety Chapter 5 Toxicology and the Treatment of Poisoning Section II: Autonomic and Neuromuscular Pharmacology Chapter 6 Peripheral Neuropharmacology and Acetylcholine Agonists Chapter 7 Acetylcholine Receptor Antagonists Chapter 8 Sympathetic Neurotransmission and Adrenoceptor Agonists Chapter 9 Adrenoceptor Antagonists Section III: Cardiovascular, Renal, and Hematologic Pharmacology Chapter 10 Antihypertensive Drugs Chapter 11 Antianginal Drugs Chapter 12 Drugs for Heart Failure Chapter 13 Diuretics Chapter 14 Drugs for Cardiac Dysrhythmia Chapter 15 Drugs for Hyperlipidemia Chapter 16 Antithrombotic and Thrombolytic Drugs Chapter 17 Hematopoietic Drugs Section IV: Central Nervous System Pharmacology Chapter 18 Introduction to Central Nervous System Pharmacology Chapter 19 Sedative-Hypnotic and Anxiolytic Drugs Chapter 20 Antiepileptic Drugs Chapter 21 Local and General Anesthetics Chapter 22 Psychotherapeutic Drugs Chapter 23 Opioid Analgesics and Antagonists Chapter 24 Drugs for Neurodegenerative Diseases Chapter 25 Drugs of Abuse Section V: Pharmacology of Respiratory and Other Systems Chapter 26 Autacoid Drugs Chapter 27 Respiratory Pharmacology Chapter 28 Gastrointestinal Pharmacology Chapter 29 Drugs for Headache Disorders Chapter 30 Drugs for Pain, Inflammation, and Arthritic Disorders Section VI: Endocrine Pharmacology Chapter 31 Hypothalamic and Pituitary Drugs Chapter 32 Thyroid Drugs Chapter 33 Adrenal Steroids and Related Drugs Chapter 34 Drugs Affecting Fertility and Reproduction Chapter 35 Drugs for Diabetes Chapter 36 Drugs Affecting Calcium and Bone Section VII: Chemotherapy Chapter 37 Principles of Antimicrobial Chemotherapy Chapter 38 Inhibitors of Bacterial Cell Wall Synthesis Chapter 39 Inhibitors of Bacterial Protein Synthesis Chapter 40 Quinolones, Antifolate Drugs, and Other Antimicrobial Agents Chapter 41 Antimycobacterial Drugs Chapter 42 Antifungal Drugs Chapter 43 Antiviral Drugs Chapter 44 Antiparasitic Drugs Chapter 45 Antineoplastic Drugs Chapter 46 Immunotherapeutic Agents

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Book SynopsisThe hands-on study companion for the most respected, rigorous medical toxicology text availableGoldfrank's Toxicologic Emergencies has long been the go-to guide for accurately diagnosing and effectively treating poisoned and overdosed patients. Now, this practical companion provides everything you need to get even more out of Goldfrankâs.Study Guide for Goldfrank's Toxicologic Emergencies provides 1,400 questions with answers for testing your knowledgeâa process that increases information retention and serves as invaluable practice for board exams. Each chapter has its own question set using both general factual and case-based questions. The guide is ideal for students, nurses, pharmacists, and physicians.Study Guide for Goldfrank's Toxicologic Emergencies covers: General approaches to the poisoned patient Principles of medical toxicology Clinical basis of medical toxicology Poison prevention and eduTable of Contents Historical Principles and Perspectives Toxicologic Misfortunes and Catastrophes in History PART A THE GENERAL APPROACH TO THE PATIENT Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes Principles of Managing the Acutely Poisoned or Overdosed Patient SC1. Principles of Antidote Stocking Decontamination Principles: Prevention of Gastrointestinal Absorption SC2. Decontamination Principles: Prevention of Dermal, ophthalmic and inhalational Absorption A1. Activated Charcoal A2. Whole-Bowel Irrigation and Other Intestinal Evacuants Principles and Techniques Applied to Enhance Elimination Laboratory Principles Principles of Diagnostic Imaging Pharmacokinetic and Toxicokinetic Principles PART B THE FUNDAMENTAL PRINCIPLES OF MEDICALTOXICOLOGY SECTION I BIOCHEMICAL AND MOLECULAR CONCEPTS Chemical Principles Biochemical and Metabolic Principles Fluid, Electrolyte, and Acid–Base Principles Neurotransmitters and Neuromodulators Withdrawal Principles SECTION II PATHOPHYSIOLOGIC BASIS: ORGAN SYSTEMS Cardiologic Principles I: Electrophysiologic and Electrocardiographic Principles Cardiologic Principles II: Hemodynamics Dermatologic Principles SC3. Transdermal Toxicology Gastrointestinal Principles Genitourinary Principles Hema tologic Principles Hepatic Principles Neurologic Principles Oncologic Principles Ophthalmic Principles Otolaryngologic Principles Psychiatric Principles SC4. patient violence Respiratory Principles Thermoregulatory Principles SECTION III SPECIALPOPULATIONS Reproductive and Perinatal Principles Pediatric Principles Geriatric Principles PART C THE CLINICAL BASIS OF MEDICAL TOXICOLOGY SECTION I A. ANALGESICS ANDANTIINFLAMMATORY MEDICATIONS Acetaminophen A3. N-Acetylcysteine Colchicine, Podophyllin, and the Vinca Alkaloids Nonsteroidal Antiinflammatory Drugs Opioids A4. opioid antagonists SC5. Internal Concealment of Xenobiotics SC6. Harm Reduction for Opioid Overdose Salicylates A5. sodium bicarbonate B. Food, Diet, and Nutrition Botulism A6. botulinum antitoxin Food Poisoning Dieting Xenobiotics and Regimens Athletic Performance Enhancers Essential Oils Plant and Animal-Derived Dietary Supplements Vitamins Iron A7. deferoxamine Mary Ann Howland C. pharmaceuticals Pharmaceutical Additives Antidiabetics and Hypoglycemics/Antiglycemics A8. Dextrose(d-Glucose) A9. octreotide Antiepileptics A10. l-carnitine Antihistamines and Decongestants A11. physostigmine salicylate Chemotherapeutics Methotrexate,5-Flourouracil, and Capecitabine A12. folates: leucovorin (Folinic acid) and Folic Acid A13. glucarpidase(carboxypeptidase g2) A14. uridine triacetate SC7. Inadvertent Intrathecal Administration of Xenobiotics SC8. Extravasation of Chemotherapeutics Antimigraine Medications Thyroid and Antithyroid Medications D. Antimicrobials Antibacterials, Antifungals, and Antivirals Antimalarials Antituberculous Medications A15. pyridoxine E. Cardiopulmonary Medications CASE STUDY 4 Antidysrhythmics A16. Magnesium Sulfate Antithrombotics A17. Protein Complex Concentrate and Novel Antithrombotic Antidotes A18. Vitamin k1 A19. protamine β-Adrenergic Antagonists A20. Glucagon

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Book SynopsisNatural toxicants have been known from ancient times and man used them to gain various benefits by producing remedies, preserving goods or using them as a means for homicide. During the past century many new, toxicologically undefined industrial substances were introduced to the environment. It was an inevitable risk that substances dangerous to man, biota and environment, every man should contribute by being aware of his surroundings. In ''General Toxicology'' the vastness of the toxicological scope is presented by outlining the possible encounter with toxicants of different origins, their fate in the human body and the effects produced. The book smoothly introduces the reader to the basic principles and mechanisms in the body exposed to ubiquitous foreign substances. The path from the exposure to xenobiotics to final effects is to encompass basic aspects of toxicokinetics, i.e. absorption, distribution, biotransformation and excretion of the substances. The mechanisms of adverse health effects are outlined by the insight in toxicodynamic processes which explains the difference between acute and chronic exposures. The occurrence, physico-chemical properties and toxicity of most important categories of both natural and anthropogenic toxicants including detailed depiction of the poisoning symptoms, are described in the important new book.

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Book SynopsisIn the midst of national concern over illicit drug use and abuse, prescription drug abuse has been identified as the United States'' fastest growing drug problem. Nearly all prescription drugs involved in overdoses are originally prescribed by a physician (rather than, for example, being stolen from pharmacies). Thus, attention has been directed toward preventing the diversion of prescription drugs after the prescriptions are dispensed. Prescription drug monitoring programs (PDMPs) maintain statewide electronic databases of prescriptions dispensed for controlled substances. This book provides an overview of PDMPs with a focus on supporting access to legitimate medical use of controlled substances; identifying or preventing drug abuse and diversion; facilitating the identification of prescription drug-addicted individuals and enabling intervention and treatment; and outlining and educating the public on drug use and abuse trends to inform public health initiatives.

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Book SynopsisBotulinism toxins are widely used for the treatment of medical and aesthetic disorders. They are considered the gold standard for the treatment of muscular spasticity and facial dynamics wrinkles. The authors'' of this book discuss botulinum toxin resistance in medical and aesthetic arenas; recommendations of dilutions for treatment applications (general recommendations were to inject the toxin diluted, because highly concentrated toxins were believed to be more toxic and dangerous); a novel methodology of transdermal delivery of botulinum toxin with the aid of a dermic pen for hyperhidrosis; emerging treatment options for lower urinary tract symptoms that involve a bladder neck injection of a botulinum toxin; and a discussion on the cases of botulism that arise from consuming certain foods particularly in the Arctic regions.

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Book SynopsisThis book offers readers an overview of the field of toxicology while incorporating historical context with present day advances. The chapters, written in a style that facilitates the reader''s connection of past developments with the present state-of-the-art practices in specific fields of toxicology, provide a detailed coverage of diverse areas in toxicology. The areas of chapters chosen for detailed discussion are characteristic of the overall field and helps to reinforce the basic principles of toxicology. As such, this book will be a valuable resource not only for those scientists in the field of toxicology, but also for those in related fields (e.g., pharmacology, physiology, microbiology, biochemistry, immunology and others). Additionally, this book will be a valuable resource for teaching graduate students in not only toxicology, but also in the related fields above. While this book is not primarily intended as an introductory text for undergraduate students'' first exposure to the field of toxicology, it would serve very useful as a text for an advanced undergraduate level biology or chemistry course. The chapters are filled with appropriate tables and figures which help illustrate and reinforce the information in each chapter. The referencing of material cited is carefully prepared and provides links to additional information that will aid the reader in understanding and appreciating the information within the text. The reader will find this book to be of significant depth and breadth so as to meet the needs of many groups of students and established scientists.

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Book SynopsisMost of What You Know About Addiction is Wrong sends out a set of well-researched, informed and timely messages about how mature societies should be handling addictive drugs. This makes the book essential reading for policy makers, politicians, health professionals as well as general readers everywhere.

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Book SynopsisThe fundamental principles of environmental toxicology are clearly presented here for university students and professionals in related fields. This book consists of two parts. In the first part basic metabolic, physiological, and pharmacological concepts are used to explain the fate of toxic chemicals in the body, with emphasis on carcinogenesis and mutagenesis. This part also contains a chapter on chemicals disrupting the endocrine system and a chapter on risk assessment and the precautionary principle. The second section deals with specific environmental problems - air pollution, alteration of the earth''s atmosphere, water and land pollution, including sections on wetlands, organic agriculture and genetically modified crops. It also deals with health and environmental effects of ionized radiation, and the effect of a rapid population growth on the environmental and human welfare. Chapter on pollution control and regulatory policies are also included.Table of ContentsPreface to the First Edition ; Preface to the Second Edition ; Preface to the Third Edition ; 1. Environment: Past and Present ; 2. Review of Pharmacologic Concepts ; 3. Metabolism of Xenobiotics ; 4. Factors That Influence Toxicity ; 5. Chemical Carcinogenesis and Mutagenesis ; 6. Endocrine Disrupters ; 7. Risk Assessment ; 8. Occupational Toxicology ; 9. Air Pollution ; 10. Pollution of the Atmosphere ; 11. Water and Land Pollution ; 12. Pollution Control ; 13. Radioactive Pollution ; 14. Population, Environment and Women's Issues ; 15. Regulatory Policies and International Treaties ; Appendix: Subject for Student Seminars ; Index

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Book SynopsisIn a devastating exposé in the tradition of Silent Spring and Fast Food Nation, investigative journalist Randall Fitzgerald warns how thousands of man-made chemicals in our food, water, medicine, and environment are making humans the most polluted species on the planet. A century ago, when Congress enacted the Pure Food and Drug Act, Americans were promised “better living through chemistry.” Fitzgerald provides overwhelming evidence to shatter this myth, and many others perpetrated by the chemical, pharmaceutical, and processed foods industries. Consider this: ·         The average American carries a body burden of 700 synthetic chemicals; ·         Chemicals in tap water can cause reproductive abnormalities and hermaphroditic birth; ·         One study of lactating women found p

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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