Physiology Books

Book SynopsisTough Test Questions? Missed Lectures? Not Enough Time?Fortunately for you, there's Schaum's. This all-in-one-package includes more than 1,400 fully solved problems, examples, and practice exercises to sharpen your problem-solving skills. Plus, you will have access to 20 detailed videos featuring Science instructors who explain the most commonly tested concepts--it's just like having your own virtual tutor! You'll find everything you need to build confidence, skills, and knowledge for the highest score possible.More than 40 million students have trusted Schaum'sto help them succeed in the classroom and on exams.Schaum's is the key to faster learning and higher gradesin every subject. Each Outline presents all the essentialcourse information in an easy-to-follow, topic-by-topicformat. You also get hundreds of examples, solvedproblems, and practice exercises to test your skills.This Schaum's Outline gives you 1,470 fully solved problems CTable of Contents1.Introduction to the Human Body2.Cellular Chemistry3.Cell Structure and Function4.Tissues5.Integumentary System6.Skeletal System7.Muscle Tissue and Mode of Contraction8.Muscular System9.Nervous Tissue10.Central Nervous System11.Peripheral and Autonomic Nervous System12.Sensory Organs13.Endocrine System14.Cardiovascular System: Blood15.Cardiovascular System: The Heart16.Cardiovascular System: Vessels and Blood Circulation17.Lymphatic System and Body Immunity18.Respiratory System19.Digestive System20.Metabolism, Nutrition, and Temperature Regulation21.Urinary System22.Water and Electrolyte Balance23.Reproductive System

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Book Synopsis''A wonderful book'' Bill Bryson''Ashcroft achieves the sort of rich simplicity most science writers can only dream about ... this book carries the eponymous spark of life'' Sunday Telegraph From before birth to the last breath we draw, from consciousness to sexual attraction, fighting infection to the beating of our hearts, electricity is essential to everything we think and do.In The Spark of Life award-winning physiologist Frances Ashcroft reveals the secrets of ion channels, which produce the electrical signals in our cells. Can someone really die of fright? How do cocaine, LSD and morphine work? Why do chilli peppers taste hot? Ashcroft explains all this and more with wit and clarity. Anyone who has ever wondered about what makes us human will find this book a revelation.''A rare gift for making difficult subjects accessible and fascinating'' Bill Bryson ''She communicates complex science with engaging passion and eloquencTrade ReviewThis is a wonderful book. Frances Ashcroft has a rare gift for making difficult subjects accessible and fascinating * Bill Bryson *

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Book SynopsisIn The Story of the Human Body, Daniel Lieberman, Professor of human evolutionary biology at Harvard, shows how we need to change our world to fit our hunter-gatherer bodiesThis ground-breaking book of popular science explores how the way we use our bodies is all wrong. From an evolutionary perspective, if normal is defined as what most people have done for millions of years, then it''s normal to walk and run 9 -15 kilometres a day to hunt and gather fresh food which is high in fibre, low in sugar, and barely processed. It''s also normal to spend much of your time nursing, napping, making stone tools, and gossiping with a small band of people. Our 21st-century lifestyles, argues Daniel Lieberman, are out of synch with our stone-age bodies. Never have we been so healthy and long-lived - but never, too, have we been so prone to a slew of problems that were, until recently, rare or unknown, from asthma, to diabetes, to - scariest of all - overpopulation.The Story of the Human Body asks how our bodies got to be the way they are, and considers how that evolutionary history - both ancient and recent - can help us evaluate how we use our bodies. How is the present-day state of the human body related to the past? And what is the human body''s future? ''Monumental. The Story of the Human Body, by one of our leading experts, takes us on an epic voyage'' - Neil Shubin, author of Your Inner Fish''Riveting, enlightening, and more than a little frightening'' - Christopher McDougall, author of Born to RunDaniel Lieberman is the Chair of the Department of Human Evolutionary Biology at Harvard and a leader in the field. He has written nearly 100 articles, many appearing in the journals Nature and Science, and his cover story on barefoot running in Nature was picked up by major media the world over. His research and discoveries have been highlighted in newspapers and magazines, including The New York Times, Boston Globe, Discover, and National Geographic.Trade ReviewMonumental. The Story of the Human Body, by one of our leading experts, takes us on an epic voyage that reveals how the past six million years shaped every part of us - our heads, limbs, and even our metabolism. Through Lieberman's eyes, evolutionary history not only comes alive, it also becomes the means to understand, and ultimately influence, our body's future -- Neil Shubin, author of Your Inner FishNo one understands the human body like Daniel Lieberman or tells its story more eloquently. He's found a tale inside our skin that's riveting, enlightening, and more than a little frightening -- Christopher McDougall, author of Born to Run

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Book SynopsisComprehensive, contemporary, and engaging, Animal Physiology provides evolutionary and ecological context to help students make connections across all levels of physiological scale. One of the major challenges instructors and students face in Animal Physiology is making connections across levels of biological scale. Animal Physiology addresses this challenge by providing ecological and evolutionary context to the study of physiology at all levels of organization: genome, molecular biology, biochemistry, cells, tissues, organs, and organ systems. Hill''s inclusion of ecology and evolution helps readers gain a holistic perspective on animal function and sets Animal Physiology apart from texts that focus more narrowly on physiology. Hill''s Animal Physiology is trusted by instructors and students because of its authoritative, current, engaging, and lavishly illustrated presentation.Table of ContentsPreface Part I Fundamentals of Physiology Chapter 1 Animals and Environments: Function on the Ecological Stage Chapter 2 Molecules and Cells in Animal Physiology Chapter 3 Genomics, Proteomics, and Related Approaches to Physiology Chapter 4 Physiological Development and Epigenetics Chapter 5 Transport of Solutes and Water Part II Food, Energy, and Temperature Chapter 6 Nutrition, Feeding, and Digestion Chapter 7 Energy Metabolism Chapter 8 Aerobic and Anaerobic Forms of Metabolism Chapter 9 The Energetics of Aerobic Activity Chapter 10 Thermal Relations Chapter 11 Food, Energy, and Temperature AT WORK: The Lives of Mammals in Frigid Places Part III Integrating Systems Chapter 12 Neurons Chapter 13 Synapses Chapter 14 Sensory Processes Chapter 15 Nervous System Organization and Biological Clocks Chapter 16 Endocrine and Neuroendocrine Physiology Chapter 17 Reproduction Chapter 18 Integrating Systems AT WORK: Animal Navigation Part IV Movement and Muscle Chapter 19 Control of Movement Chapter 20 Muscle Chapter 21 Movement and Muscle AT WORK: Plasticity in Response to Use and Disuse Part V Oxygen, Carbon Dioxide, and Internal Transport Chapter 22 Introduction to Oxygen and Carbon Dioxide in Physiology Chapter 23 External Respiration: The Physiology of Breathing Chapter 24 Transport of Oxygen and Carbon Dioxide in Body Fluids (with an Introduction to Acid- Base Physiology) Chapter 25 Circulation Chapter 26 Oxygen, Carbon Dioxide, and Internal Transport AT WORK: Diving by Marine Mammals Part VI Water, Salts, and Excretion Chapter 27 Water and Salt Physiology: Introduction and Mechanisms Chapter 28 Water and Salt Physiology of Animals in Their Environments Chapter 29 Kidneys and Excretion (with Notes on Nitrogen Excretion) Chapter 30 Water, Salts, and Excretion AT WORK: Mammals of Deserts and Dry Savannas Appendix A The Système International and Other Units of Measure Appendix B Prefixes Indicating Orders of Magnitude Appendix C Gases at Standard Temperature and Pressure Appendix D Logarithms Appendix E Exponential and Allometric Equations Appendix F Phylogenetically Independent Contrasts Appendix G The Standard Amino Acids Appendix H Basic Physics Terms Appendix I Summary of Major Bloodborne Hormones in Mammals E-book/online only: Appendix J Fitting Lines to Data Appendix K Mitosis and Meiosis Glossary Index

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Book SynopsisPlant Physiology and Development incorporates the latest advances in plant biology, making Plant Physiology the most authoritative and widely used upper-division plant biology textbook. Up to date, comprehensive, and meticulously illustrated, the improved integration of developmental material throughout the text ensures that Plant Physiology and Development provides the best educational foundation possible for the next generation of plant biologists.This new, updated edition includes current information to improve understanding while maintaining the core structure of the book. Figures have been revised and simplified wherever possible. To eliminate redundancy, stomatal function (Chapter 10 in the previous edition) has been reassigned to other chapters. In addition, a series of feature boxes related to climate change are also included in this edition.An enhanced ebook with embedded self-assessment, Web Topics and Web Essays and Study Questions is available with this edition.Trade ReviewAn excellent textbook for use in both plant physiology and plant biochemistry courses. The book presents concepts in language undergraduates readily grasp, with excellent illustrations, as well as great digital resources for the instructors." - Joshua BlakesleeThe integration of climate change is a huge bonus to me and one that I think will make the material more relevant to students." - Danielle WayWell organized description of the minerals needed by plants, why they are needed, and a good review of uptake and implications of this to the larger picture or general plant adaptions envinmental concerns." - Joseph SullivanIt is an excellent textbook for introductory plant physiology that covers all most all aspects of plant growth nd development." - Susheng GanAll things considered, this international 7th edition of Plant Physiology and Development by Lincoln Taiz, Ian Max Møller, Angus Murphy and Eduardo Zeiger is a most impressive textbook - for the subjects it covers. * Nigel Chaffey, Botany One *Table of ContentsI. Structure and Information Systems of Plant Cells 1 Plant and Cell Architecture 2 Cell Walls: Structure, Formation, and Expansion 3 Genome Structure and Gene Expression 4 Signals and Signal Transduction II. Transport and Translocation of Water and Solutes 5 Water and Plant Cells 6 Water Balance of Plants 7 Mineral Nutrition 8 Solute Transport III. Biochemistry and Metabolism 9 Photosynthesis: The Light Reactions 10 Photosynthesis: The Carbon Reactions 11 Photosynthesis: Physiological and Ecological Considerations 12 Translocation in the Phloem 13 Respiration and Lipid Metabolism 14 Assimilation of Inorganic Nutrients 15 Abiotic Stress IV. Growth and Development 16 Signals from Sunlight 17 Germination and Establishment 18 Vegetative Growth on the Primary Axis 19 Secondary Vegetative Growth 20 Control of Flowering and Floral Development 21 Gametophyte Development, Pollination, and Fruit Development 22 Embryogenesis: The Origin of Plant Architecture 23 Plant Senescence and Cell Death 24 Biotic Interactions

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Book SynopsisThe human body is a complicated and beautiful machine, governed by the laws of physics and chemistry. By understanding its physiology - how it performs its varied functions - it is possible to build strategies for diagnosis, treatment, and prevention of disease. In this latest edition, expanded and restructured coverage of sensory physiology and the respiratory system, a new comprehensive glossary of key terms, and additional online learning resources make Human Physiology even more student-friendly than its predecessors. Human Physiology provides clear explanations of the principles that govern the body''s physiological processes and shows how these can be applied. This is the ideal course companion for any student needing a solid foundation in the subject for a future career in human biology, biomedical science, or medicine. Online resourcesStudent resources- Numerical and clinical problems - Multiple choice questions - Web linksLecturer resources- Figures from the bookTrade ReviewReview from previous edition Helped me to pass my first year of university with a First Class. Would recommend as it details many important concepts and explains them really easily. * Amazon customer review *An excellent book; very well explained and very detailed. * Amazon customer review *This welcomed fourth edition builds upon the positive aspects of previous editions and provides a fresh perspective to a complex area of study. Ease of reading and understanding is a key strength for this text and students will obtain detailed content, balanced with key effective learning tools to enhance knowledge exchange. * Dr Jamie O'Driscoll, Department of Sport Science, Tourism and Leisure, Canterbury Christ Church University *Table of ContentsSECTION 1 BASIC CONCEPTS IN PHYSIOLOGY; SECTION 2 THE ORGANIZATION AND BASIC FUNCTIONS OF CELLS; SECTION 3 THE EXCITABLE TISSUES - NERVE AND MUSCLE; SECTION 4 THE NERVOUS SYSTEM AND SPECIAL SENSES; SECTION 5 THE ENDOCRINE SYSTEM; SECTION 6 BLOOD AND THE IMMUNE SYSTEM; SECTION 7 THE CARDIOVASCULAR SYSTEM; SECTION 8 THE RESPIRATORY SYSTEM; SECTION 9 THE REGULATION OF THE INTERNAL ENVIRONMENT; SECTION 10 THE GASTROINTESTINAL SYSTEM; SECTION 11 REPRODUCTION AND GROWTH

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Book SynopsisThe Thrive in Bioscience revision guides are written to help students achieve exam success in all core areas of bioscience. Each title encourages the reader to follow four steps to maximise their learning, with features to support this process. Step one: Review the factsThe revision guides are designed to help learning be quick and effective: Information is set out in bullet points, making it easy to digest Clear, uncluttered illustrations illuminate what is said in the text Key concept panels summarise the essential learning points Step two: Check your understandingReaders are encouraged to: Complete the questions at the end of chapters and online multiple-choice questions to reinforce their learning Use the flashcard app to master the essential terms and phrasesStep three: Take note of extra adviceRevision tips, and hints for getting those precious extra marks in exams, are presented throughout. Step four: Go the extra mileReaders can explore the suggestions for further reading to tTable of Contents1. Introduction to human physiology ; 2. Control and co-ordination I - the nervous system ; 3. Control and co-ordination II - the endocrine system ; 4. Musculoskeletal physiology and movement ; 5. Cardiovascular physiology ; 6. Respiratory physiology ; 7. Renal physiology ; 8. Gastrointestinal physiology ; 9. Reproductive physiology ; 10. Integrative physiology

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Book SynopsisHormones are vital to the workings of the body, and while many people are aware of what hormones do, few have an appreciation of the nature and importance of the endocrine system. In this Very Short Introduction, Martin Luck explains what hormones are, what they do, where they come from, and how they work.Trade Reviewan informative and readable overview to the subject * Guardian *Table of Contents1. Hormones, history, and the shoulders of giants ; 2. What and how ; 3. Nuns, catastrophes, and the mysteries of reproduction ; 4. Water, salt, and blood pressure ; 5. The hard stuff: calcium, cells, bones, and cancer ; 6. Appetite, fat, and obesity ; 7. The thyroid gland ; 8. Light and dark ; 9. Changing perspectives ; Further reading ; Index

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Book SynopsisBiomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible. The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science.Clinical Biochemistry provides a clear and comprehensive introduction to the biochemical basis of disease proceTable of Contents1: David Cameron: Biochemical investigations and quality control 2: Tim James: Automation 3: Edmund Lamb: Kidney disease 4: Joanne Marsden: Hyperuricaemia and gout 5: Tim James: Fluid and electrolyte disorders 6: David Tierney: Acid-base disorders 7: Paul Collinson and Amy Lloyd: Clinical enzymology and biomarkers 8: Roy Sherwood: Liver function tests 9: Mike France: Abnormalities of lipid metabolism 10: Nessar Ahmed: Disorders of calcium, phosphate, and magnesium homeostasis 11: Garry McDowell: Abnormal pituitary function 12: Garry McDowell: Thyroid disease 13: Allen Yates and Ian Laing: Diabetes mellitus and hypoglycaemia 14: John Honour: Adrenal disease 15: Ian Laing and Julie Thornton: Reproductive endocrinology 16: Pat Twomey and William Simpson: Biochemical nutrition 17: Garry McDowell and Gordon Brydon: Gastrointestinal disorders and malabsorption 18: Gerald Maguire: Specific protein markers 19: Joanne Adaway and Gilbert Wieringa: Cancer biochemistry and tumour markers 20: Mary Anne Preece: Inherited metabolic disorders and newborn screening 21: Robin Whelpton, Nigel Brown, and Robert Flanagan: Therapeutic drug monitoring 22: Gwendolen Ayers: Chemical toxicology

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Book SynopsisWhy does holding a hot drink make us like people more?How can a soldier under fire not even notice he''s been shot?What makes sex so much fun?Touch is the most important sense we have. Without it, we cannot entirely feel pleasure or pain - we are less than human.In fact, as David Linden demonstrates in the astonishing stories gathered here, touch is central to who we are - from choosing our partners to comforting us on our deathbeds.Exploring the many surprising facts and myths about our sense of touch, Linden reveals how it defines us - and how, by understanding it, we can better know ourselves.Trade ReviewIlluminating. Drawing on a wide range of cutting-edge scientific research, Linden provides plenty of insights into how our sense of touch shapes our experience of the world and our idea of self * Sunday Times *This book is excellent. It tells you why footballers hug each other when a goal is scored, and why there are vampire bats. Linden is very good and clear on the raw neurology * Spectator *Absorbing. The bizarre vagaries of touch affect us all, [and] all this is backed up with a good deal of hard neuroscience. Following Linden's thread is worth it * The Times *Most of us take the tactile senses for granted. You won't after reading this book. The best science writers infect you with their fascination for the subject - that's exactly what Linden achieves here * BBC Focus *A treasure trove for anyone wanting to decode the frisson of a lover's caress * Playboy *Will make you think more deeply about every itch, scrape and caress * Washington Post *Fascinating. This book has changed my life -- Salley Vickers * Observer *A touching story? A tactless comment? So elemental is the sense of touch that it permeates metaphors we live by. Linden explores the 'weird, complex, and often counter-intuitive' tactile system and its intimate impact on the human experience * Nature *

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Book SynopsisAlmost all bodily functions are dependent on activity of the autonomic nervous system from the cardiovascular system, the gastrointestinal tract, the evacuative and sexual organs, to the regulation of temperature, metabolism and tissue defence. Balanced functioning of each aspect of this system is an important basis of our life and well-being. In this long-awaited second edition, the author, a leading figure in this field, provides an up-to-date and detailed description of the cellular and integrative organization of the autonomic nervous system, covering both peripheral and central aspects. The book exposes modern neurobiological concepts that allow us to understand why this system normally runs so smoothly and why its deterioration has such disastrous consequences. This broad overview will appeal to researchers and advanced undergraduate students of the various biological and medical sciences studying how the autonomic nervous system works and to clinicians and physical therapists whose practice involves systems dependent on autonomic functions.Trade Review'This is the ultimate resource for anyone interested in autonomic neurosciences. Professor Jänig has tastefully updated a classic book which manages to distill a vast body of knowledge that will continue to be cherished by students as well as established scientists.' Kalyanam Shivkumar, Professor of Medicine, The University of California, Los Angeles (UCLA), and President, International Society for Autonomic Neuroscience (ISAN 2022)'Wilfrid Jänig has produced an outstanding synthesis of the state of knowledge of the autonomic nervous system (ANS). The book is far more than a summary of knowledge; Jänig has drawn out important principles from experimental work and his deep understanding of physiology. He shows how the ANS, in partnership with endocrine hormones, purposefully maintains cells, tissues, and organs in their optimal functional states. The book is beautifully illustrated, especially with diagrams of autonomic circuits. Also very helpful are the conclusions paragraphs at the ends of chapters. The book is essential reading for the seriously engaged physiologist and physician.' John B. Furness, Professor of Anatomy and Physiology, The University of Melbourne and The Florey Institute of Neuroscience and Mental Health'This is the 'Workshop Manual' of how the autonomic nervous system works. The integrative aspect of this book is quite superb. Jänig has avoided the traditional, and unhelpful, silo approach where bodily systems are separated in distinct chapters. This is inconsistent with how the body works. This new edition leaves no 'autonomic' stone unturned, covering endplates to emotion, credits the historical facts that have stood the test of time but kicks those into touch that have not. So pleasing was to see that the book challenges old/outdated dogma and sets the facts straight by reviewing the most current evidence. I know that my copy of this book will spend its life being read and not on a shelf; it will be poured over by professors and students alike. The illustrations require a mention: they are exceptional - clear, concise, and comprehensive. I believe this book will put the autonomic nervous system front and center in the field of neuroscience.' Julian F.R. Paton, Professor of Translational Physiology, University of Auckland, New ZealandTable of ContentsForeword to the Second Edition Elspeth McLachlan; Foreword to the First Edition Elspeth McLachlan; Preface; List of abbreviations; Introduction: The autonomic nervous system and the regulation of body functions; Part I. The Autonomic Nervous System: Functional Anatomy and Interoceptive Afferents: 1. Functional anatomy of the peripheral sympathetic and parasympathetic nervous system; 2. Interoceptive afferent neurons and autonomic regulation with special emphasis on the viscera; Part II. Functional Organization of the Peripheral Autonomic Nervous System: 3. The final autonomic pathway and its analysis; 4. The peripheral sympathetic and parasympathetic pathways; 5. The enteric nervous system; Part III. Transmission of Signals in the Peripheral Autonomic Nervous System: 6. Impulse transmission through autonomic ganglia; 7. Mechanisms of neuroeffector transmission; Part IV. Representation of the Autonomic Nervous System in Spinal Cord, and Lower Brain Stem: 8. Anatomy of central autonomic systems; 9. Spinal autonomic systems; 10. Regulation of organ systems by the lower brain stem; Part V. The Centers of Homeostasis in the Mesencephalon and Hypothalamus and their Telencephalic Control: 11. Integration of autonomic regulation in upper brain stem and limbic-hypothalamic centers: a summary; Epilogue The autonomic system in future research: some personal views; Index.

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Book SynopsisAbout our authors Frederic (Ric) H. Martini, Ph.D. Dr. Martini received his Ph.D. from Cornell University in comparative and functional anatomy for work on the pathophysiology of stress. In addition to professional publications that include journal articles and contributed chapters, technical reports, and magazine articles, he is the lead author of 10 undergraduate texts on anatomy and physiology. He has also published books on tropical islands, on WWII history, and in science fiction. Dr. Martini has a long-standing bond with the Shoals Marine Laboratory, a joint venture between Cornell University and the University of New Hampshire, where he received his undergraduate degree. He has been active in the Human Anatomy and Physiology Society (HAPS) for over 30 years and was a member of the committee that established the course curriculum guidelines for A&P. He is a President Emeritus of HAPS after serving as President-Elect, President, and Past-PresideTable of ContentsUNIT 1: LEVELS OF ORGANIZATION 1: An Introduction to Anatomy and Physiology The Chemical Level of Organization The Cellular Level of Organization The Tissue Level of Organization UNIT 2: SUPPORT AND MOVEMENT The Integumentary System Bones and Bone Structure The Axial Skeleton The Appendicular Skeleton Joints Muscle Tissue The Muscular System UNIT 3: CONTROL AND REGULATION Nervous Tissue The Spinal Cord, Spinal Nerves and Spinal Reflexes The Brain and Cranial Nerves Sensory Pathways and the Somatic Nervous System The Autonomic Nervous System and Higher Order Functions The Special Senses The Endocrine System UNIT 4: FLUIDS AND TRANSPORT Blood The Heart Blood Vessels and Circulation The Lymphatic System and Immunity UNIT 5: ENVIRONMENTAL EXCHANGE The Respiratory System The Digestive System Metabolism, Nutrition and Energetics The Urinary System Fluid, Electrolyte and Acid-Base Balance UNIT 6: CONTINUITY OF LIFE The Reproductive System Development and Inheritance APPENDICES A. Normal Physiological Values B. Gas Pressure Measurements C. Turnover Times for Selected Cells D. Codon Chart E. The Periodic Table

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Book SynopsisThere's a silent epidemic in western civilization, and it is right under our noses. Our jaws are getting smaller and our teeth crooked and crowded, creating not only aesthetic challenges but also difficulties with breathing. Modern orthodontics has persuaded us that braces and oral devices can correct these problems. While teeth can certainly be straightened, what about the underlying causes of this rapid shift in oral evolution and the health risks posed by obstructed airways? Sandra Kahn and Paul R. Ehrlich, a pioneering orthodontist and a world-renowned evolutionist, respectively, present the biological, dietary, and cultural changes that have driven us toward this major health challenge. They propose simple adjustments that can alleviate this developing crisis, as well as a major alternative to orthodontics that promises more significant long-term relief. Jaws will change your life. Every parent should read this book.Trade Review"Paul Ehrlich is the world's best-known and most distinguished ecologist, and one of the best known figures in any field of science. Now, teaming up with Sandra Kahn, he offers us his most personal and practical book to date. You'll discover the widespread consequences of how you carry out such seemingly mundane, automatic, and repetitive acts as breathing, smiling, and sleeping—and how your ways of doing those things affect peoples' perceptions of you. Read, enjoy, learn, and prepare to be astonished!"—Jared Diamond, Pulitzer-Prize-winning author of Guns, Germs, and Steel "The specialty of orthodontics has the potential to lead the way out of this epidemic of chronic disease (including malocclusion). We need only read and understand this book first."—Barry Raphael, Head of the Raphael Center for Integrative Orthodontics"People have some power to protect their children from this serious and cryptic environmental problem. Jaws lays out both causes and cures."—Gretchen C. Daily, Bing Professor of Environmental Science, Stanford UniversityJaws is a must read for every parent on this planet. It addresses the causes of our chronic health crisis and tells us how to prevent it while correcting our faces, jaws and airways. Airway health will give the most added value for this generation's overall wellness."—Michael Gelb DDS, MS"Jaws: The Story of a Hidden Epidemic is a well-researched book providing unique overview and insight in to a healthcare problem frequently overlooked by child healthcare professionals. Sleep is likely as important to health and well-being as food, but receives little attention. This book is an important read for all professionals who care for children. It also asks questions for possible future research in the field of pediatric obstructive sleep disordered breathing."—Stephen H. Sheldon, author of Principles and Practice of Pediatric Sleep Medicine"Drs. Kahn and Ehrlich's cogent narrative describing the structural, functional and behavioral changes in the human species truly challenges the cultural and educational orthodoxies in the West's disease management healthcare system. It begs the question, 'why did it take so long to bring this enlightened insight into mainstream thought with all the available evidence presented?' The answer to this question is meticulously answered in the very readable pages of this important work; read on!"—Mark A. Cruz, DDS, The Airway and Facial Development Collaborative"Elucidation of what can be called a classic public health risk factor for a little understood disease, one with heavy influence of both social determinants and individual behaviors as well as their interactions."—Kirk R. Smith, University of California, Berkeley"Your Oral Posture is your future."—John Mew, Head of the London School of Facial Orthotropics"Every parent wants their child to grow strong and healthy. Orthodontics chosen for your child can be the most important choice to give a structural foundation to health. Sandra and Paul present important information that any parent should know about in order to give their children the cranial facial structure for beauty and health. This is a brilliant work by two brilliant scientists."—Mark Abrahamson, Stanford Center for Integrative Medicine"This manuscript looks beyond the flashy smile that so many of us pay our orthodontists for and asks the hard question: Why is it we are almost all born with the faces of angels, yet so few maintain that face value of our innate and inborn beauty? The answer revealed is intriguing, thought provoking and a much needed call to action to fight for the fullest physical potential for all our children. A must read!"—Simon Wong, BDSc., London School of Facial Orthotropics"Everyone who is concerned about health needs to have this information."—William M. Hang DDS, MSD"About 90 percent of our children have bite problems. When more than 50 percent of a population has a problem it is an epidemic. Sandra Kahn and Paul Ehrlich present the causes and consequences of this epidemic affecting our young generations. This book educates the public and dental community on treating and preventing the underlying problem, instead of just aligning teeth."—German Ramirez-Yañez DDS, MDSc, MSc, PhD"Every new parent should chew on this book. Who knew that how we suckle, chew and breathe as an infant can set us off on a course toward serious orthodontic treatment, a life of sleep apnea, cardiovascular problems and sudden death while sleeping? Kahn and Ehrlich clearly and comprehensively describe a hidden epidemic that impairs the health of far too many people, young and old. They explore the causes of the epidemic, and crucially, provide practical advice that helps you prevent the epidemic from affecting your child, or amazingly, how its progress can be reversed in childhood if it has already started. This book should be in every new mom's care package when she leaves the hospital."—John Peterson Myers, Chief Scientist, Environmental Health Sciences"Sandra Kahn and Paul Ehrlich clearly define and explain the hidden epidemic that exists around us. Emphasizing prevention and cure rather than symptom management, this book is a must read."—Dror Aizenbud, DMD, MSc, Rambam Medical Campus, Technion-Israel Institute of Technology, Haifa, Israel"This epidemic has important consequences for heart health. I'm delighted Jaws is bringing it home to both citizens and health care professionals."—Dr. John S. Schroeder, Professor of Cardiovascular Medicine, Stanford UniversityTable of Contents1. Primitive Big Mouths to Modern Malocclusion 2. Mostly Chewing 3. The Diet, Posture, and Housing Revolutions 4. Appearance 5. Development and Oral Posture 6. Disorders of Breathing and Sleep 7. What Can You Do? 8. Orthodontics, Dental Orthopedists, Orthotropists, and Forwardontists 9. Changing Culture, Improving Health

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Book SynopsisDeveloped by internationally renowned neuro-surgeons, this book is designed for students of psychology and the biological sciences, and medical, dental, and nursing students.

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Book SynopsisTable of ContentsSECTION I, Fundamental Physicochemical Concepts CHAPTER 1, INTRODUCTION: HOMEOSTASIS AND CELLULAR PHYSIOLOGY Homeostasis Enables the Body to Survive in Diverse Environments The Body Is an Ensemble of Functionally and Spatially Distinct Compartments Transport Processes Are Essential to Physiological Function Cellular Physiology Focuses on Membrane-Mediated Processes and on Muscle Function Summary Key Words and Concepts CHAPTER 2, DIFFUSION AND PERMEABILITY Diffusion Is the Migration of Molecules down a Concentration Gradient Fick's First Law of Diffusion Summarizes our Intuitive Understanding of Diffusion Essential Aspects of Diffusion Are Revealed by Quantitative Examination of Random, Microscopic Movements of Molecules Fick's First Law Can Be Used to Describe Diffusion across a Membrane Barrier Summary Key Words and Concepts Study Problems CHAPTER 3, OSMOTIC PRESSURE AND WATER MOVEMENT Osmosis Is the Transport of Solvent Driven by a Difference in Solute Concentration Across a Membrane That Is Impermeable to Solute Water Transport during Osmosis Leads to Changes in Volume Osmotic Pressure Drives the Net Transport of Water during Osmosis Osmotic Pressure and Hydrostatic Pressure Are Functionally Equivalent in Their Ability to Drive Water Movement Through a Membrane Only Impermeant Solutes Can Have Permanent Osmotic Effects Summary Key Words and Concepts Study Problems CHAPTER 4, ELECTRICAL CONSEQUENCES OF IONIC GRADIENTS Ions Are Typically Present at Different Concentrations on Opposite Sides of a Biomembrane Selective Ionic Permeability Through Membranes Has Electrical Consequences: The Nernst Equation The Stable Resting Membrane Potential in a Living Cell Is Established by Balancing Multiple Ionic Fluxes The Cell Can Change Its Membrane Potential by Selectively Changing Membrane Permeability to Certain Ions The Donnan Effect Is an Osmotic Threat to Living Cells Summary Key Words and Concepts Study Problems SECTION II, Ion Channels and Excitable Membranes CHAPTER 5, ION CHANNELS Ion Channels Are Critical Determinants of the Electrical Behavior of Membranes Distinct Types of Ion Channels Have Several Common Properties Ion Channels Share Structural Similarities and Can Be Grouped into Gene Families Summary Key Words and Concepts Study Problems CHAPTER 6, PASSIVE ELECTRICAL PROPERTIES OF MEMBRANES The Time Course and Spread of Membrane Potential Changes Are Predicted by the Passive Electrical Properties of the Membrane The Equivalent Circuit of a Membrane Has a Resistor in Parallel with a Capacitor Passive Membrane Properties Produce Linear Current-Voltage Relationships Membrane Capacitance Affects the Time Course of Voltage Changes Membrane and Axoplasmic Resistances Affect the Passive Spread of Subthreshold Electrical Signals Summary Key Words and Concepts Study Problems CHAPTER 7, GENERATION AND PROPAGATION OF THE ACTION POTENTIAL The Action Potential Is a Rapid and Transient Depolarization of the Membrane Potential in Electrically Excitable Cells Ion Channel Function Is Studied with a Voltage Clamp Individual Ion Channels Have Two Conductance Levels Na+ Channels Inactivate during Maintained Depolarization Action Potentials Are Generated by Voltage-Gated Na+ and K+ Channels Action Potential Propagation Occurs as a Result of Local Circuit Currents Summary Key Words and Concepts Study Problems CHAPTER 8, ION CHANNEL DIVERSITY Various Types of Ion Channels Help to Regulate Cellular Processes Voltage-Gated Ca2+ Channels Contribute to Electrical Activity and Mediate Ca2+ Entry into Cells Many Members of the Transient Receptor Potential Superfamily of Channels Mediate Ca2+ Entry K+-Selective Channels Are the Most Diverse Type of Channel Ion Channel Activity Can Be Regulated by Second-Messenger Pathways Summary Key Words and Concepts Study Problems SECTION III, Solute Transport CHAPTER 9, ELECTROCHEMICAL POTENTIAL ENERGY AND TRANSPORT PROCESSES Electrochemical Potential Energy Drives All Transport Processes Summary Key Words and Concepts Study Problems CHAPTER 10, PASSIVE SOLUTE TRANSPORT Diffusion across Biological Membranes Is Limited by Lipid Solubility Channel, Carrier, and Pump Proteins Mediate Transport across Biological Membranes Carriers Are Integral Membrane Proteins That Open to Only One Side of the Membrane at a Time Coupling the Transport of One Solute to the "Downhill" Transport of Another Solute Enables Carriers to Move the Cotransported or Countertransported Solute "Uphill" against an Electrochemical Gradient Net Transport of Some Solutes across Epithelia Is Effected by Coupling Two Transport Processes in Series Na+ Is Exchanged for Solutes Such as Ca2+ and H+ by Countertransport Mechanisms Multiple Transport Systems Can Be Functionally Coupled Summary Key Words and Concepts Study Problems CHAPTER 11, ACTIVE TRANSPORT Primary Active Transport Converts the Chemical Energy from ATP into Electrochemical Potential Energy Stored in Solute Gradients The Plasma Membrane Na+ Pump (Na+, K+-ATPase) Maintains the Low Na+ and High K+ Concentrations in the Cytosol Intracellular Ca2+ Signaling Is Universal and Is Closely Tied to Ca2+ Homeostasis Several Other Plasma Membrane Transport ATPases Are Physiologically Important Net Transport across Epithelial Cells Depends on the Coupling of Apical and Basolateral Membrane Transport Systems Summary Key Words and Concepts Study Problems SECTION IV, Physiology of Synaptic Transmission CHAPTER 12, SYNAPTIC PHYSIOLOGY I The Synapse Is a Junction Between Cells That Is Specialized for Cell-Cell Signaling Neurons Communicate with Other Neurons and with Muscle by Releasing Neurotransmitters The Synaptic Vesicle Cycle Is a Precisely Choreographed Process for Delivering Neurotransmitter into the Synaptic Cleft Short-Term Synaptic Plasticity Is a Transient, Use-Dependent Change in the Efficacy of Synaptic Transmission Summary Key Words and Concepts Study Problems CHAPTER 13, SYNAPTIC PHYSIOLOGY II Chemical Synapses Afford Specificity, Variety, and Fine Tuning of Neurotransmission Receptors Mediate the Actions of Neurotransmitters in Postsynaptic Cells Acetylcholine Receptors Can Be Ionotropic or Metabotropic Amino Acid Neurotransmitters Mediate Many Excitatory and Inhibitory Responses in the Brain Neurotransmitters That Bind to Ionotropic Receptors Cause Membrane Conductance Changes Biogenic Amines, Purines, and Neuropeptides Are Important Classes of Transmitters with a Wide Spectrum of Actions Unconventional Neurotransmitters Modulate Many Complex Physiological Responses Long-Term Synaptic Potentiation and Depression Are Persistent Changes in the Efficacy of Synaptic Transmission Induced by Neural Activity Summary Key Words and Concepts Study Problems SECTION V, Molecular Motors and Muscle Contraction CHAPTER 14, MOLECULAR MOTORS AND THE MECHANISM OF MUSCLE CONTRACTION Molecular Motors Produce Movement by Converting Chemical Energy into Kinetic Energy Single Skeletal Muscle Fibers Are Composed of Many Myofibrils The Sarcomere Is the Basic Unit of Contraction in Skeletal Muscle Muscle Contraction Results from Thick and Thin Filaments Sliding Past Each Other (The "Sliding Filament" Mechanism) The Cross-Bridge Cycle Powers Muscle Contraction In Skeletal and Cardiac Muscles, Ca2+ Activates Contraction by Binding to the Regulatory Protein Troponin C The Structure and Function of Cardiac Muscle and Smooth Muscle Are Distinctly Different from Those of Skeletal Muscle Summary Key Words and Concepts Study Problems CHAPTER 15, EXCITATION-CONTRACTION COUPLING IN MUSCLE Skeletal Muscle Contraction Is Initiated by a Depolarization of the Surface Membrane Direct Mechanical Interaction Between Sarcolemmal and Sarcoplasmic Reticulum Membrane Proteins Mediates Excitation-Contraction Coupling in Skeletal Muscle Ca2+-Induced Ca2+ Release Is Central to Excitation-Contraction Coupling in Cardiac MuscleSmooth Muscle Excitation-Contraction Coupling Is Fundamentally Different from That in Skeletal and Cardiac Muscles Summary Key Words and Concepts Study Problems CHAPTER 16, MECHANICS OF MUSCLE CONTRACTION The Total Force Generated by a Skeletal Muscle Can Be Varied Skeletal Muscle Mechanics Is Characterized by Two Fundamental Relationships There Are Three Types of Skeletal Muscle Motor Units The Force Generated by Cardiac Muscle Is Regulated by Mechanisms That Control Intracellular Ca2+ Mechanical Properties of Cardiac and Skeletal Muscle Are Similar but Quantitatively Different Dynamics of Smooth Muscle Contraction Differ Markedly from Those of Skeletal and Cardiac Muscle The Relationships among Intracellular Ca2+, Myosin Light Chain Phosphorylation, and Force in Smooth Muscles Is Complex Summary Key Words and Concepts Study Problems SEction VI Epilogue and Appendicies EPILOGUE APPENDIX A, ABBREVIATIONS, SYMBOLS, AND NUMERICAL CONSTANTS Abbreviations Symbols Numerical Constants APPENDIX B, A MATHEMATICAL REFRESHER Exponents Logarithms Solving Quadratic Equations Differentiation and Derivatives Integration: The Antiderivative and the Definite Integral Differential Equations APPENDIX C, ROOT-MEAN-SQUARED DISPLACEMENT OF DIFFUSING MOLECULES APPENDIX D, SUMMARY OF ELEMENTARY CIRCUIT THEORY Cell Membranes Are Modeled with Electrical Circuits Definitions of Electrical Parameters Current Flow in Simple Circuits APPENDIX E, ANSWERS TO STUDY PROBLEMS APPENDIX F, REVIEW EXAMINATION Answers to Review Examination

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Book SynopsisTable of ContentsSection I: Pathophysiology: Background and Overview 1. Introduction to Pathophysiology 2. Fluid, Electrolyte, and Acid-Base Imbalances 3. Introduction to Basic Pharmacology and Other Common Therapies 4. Pain Section II: Defense/Protective 5. Inflammation and Healing 6. Infection 7. Immunity Section III: Pathophysiology of Body Systems 8. Skin Disorders 9. Musculoskeletal Disorders 10. Blood and the Circulatory System 11. Lymphatic System Disorders 12. Cardiovascular System Disorders 13. Respiratory System Disorders 14. Neurological Disorders 15. Eyes, Ears and Other Sensory Organs 16. Endocrine Disorders 17. Digestive System Disorders 18. Urinary System Disorders 19. Reproductive System Disorders 20. Neoplasms and Cancer Section IV: Factors Contributing to Pathophysiology 21. Congenital and Genetic Disorders 22. Complications Due to Pregnancy 23. Complications Due to Adolescence 24. Complications Due to Aging Section V: Environmental Factors and Pathophysiology 25. Immobility and Associated Problems 26. Stress and Associated Problems 27. Substance Abuse and Associated Problems 28. Environmental Hazards and Associated Problems

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Book SynopsisTable of ContentsSection 1 The body and its constituents 1 Anatomy and organisation of the body 2 Physiological chemistry and processes 3 Cells and tissues Section 2 Communication 4 The blood 5 The cardiovascular system 6 The lymphatic system 7 The nervous system 8 The special senses 9 The endocrine system Section 3 Intake of raw materials and elimination of waste 10 The respiratory system 11 Introduction to nutrition 12 The digestive system 13 The urinary system Section 4 Protection and survival 14 The skin 15 Resistance and immunity 16 The musculoskeletal system 17 Introduction to genetics 18 The reproductive systems Glossary Normal values Bibliography

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Book SynopsisTable of ContentsCellular Physiology The Nervous System Muscle The Cardiovascular System The Respiratory System Gastrointestinal Physiology The Renal System The Endocrine and Reproductive Systems

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Book SynopsisTable of Contents1. Life span-related mental health disorders and cognitive behavioral therapy Rajkumar Rajendram, Vinood B. Patel, and Victor R. Preedy Section A. Pregnancy and childbirth 2. Cognitive-behavioral therapy in female infertility Susmita Halder and Sampurna Chakraborty 3. Cognitive behavioral therapy for perinatal depression—Tailored face-to-face treatment and translation for online delivery of MumMoodBooster Jeannette Milgrom, Michele Burn, Andre L. Rodrigues, Alan W. Gemmill, and Yafit Hirshler 4. Childbirth-related fear, tokophobia, and cognitive behavioral therapy Colin R. Martin, Catriona Jones, Claire Marshall, and Julie Jomeen 5. Postnatal depression: Cognitive behavioral conceptualization and prevention and treatment approaches Ana Fonseca 6. Stress and cortisol regulation during pregnancy: Implications for cognitive behavioral stress management among low-income women Guido G. Urizar, Jr. Section B. Children and adolescents 7. Adolescent acne excorie: Features and the use of cognitive behavioral therapy Arezoo Moradi Tavallaei, Maryam Saeidi Sardabi, and Mahdi Razmara Ferezghi 8. Adolescent social anxiety: Bridging cognitive and social behavioral perspectives through a developmental lens Anne C. Miers and Carrie Masia Warner 9. Skin picking and hair pulling disorders in children and adolescents: The role of cognitive behavior therapy Andrea Pozza 10. Cognitive behavioral therapy for child and adolescent hoarding disorder Davíð R.M.A. Højgaard and Gudmundur Skarphedinsson 11. School-based cognitive behavioral interventions for youth with anxiety Bente Storm Mowatt Haugland, Gro Janne Wergeland, and Elisabeth Bakke Husabø 12. Adolescents, Asperger syndrome, depression, and cognitive behavioral therapy Jaiganesh Selvapandiyan 13. Cognitive behavioral therapy for cannabis use disorder: A focus on adolescents Alba González-Roz, Víctor Martínez-Loredo, Roberto Secades-Villa, and Sergio Fernández-Artamendi 14. Anxiety in youth with asthma and cognitive behavioral therapy Gemma Sicouri 15. Cognitive-behavioral therapy adapted for youth with comorbid anxiety and autism spectrum disorder Kristen H. Erps, Emily R. Jellinek, Lindsey N. Landry, Andrew G. Guzick, Sophie C. Schneider, and Eric A. Storch 16. Cognitive-behavioral therapy for children with autism and anxiety Amanda R. Johnson, Samara Wolpe, Ingrid S. Tien, Virginia Sklar Muscatello, and Jeffrey J. Wood 17. The use of dialectical behavior therapy in childhood and adolescent eating disorders Rebecca C. Kamody and E. Thomaseo Burton 18. CBT interventions for pediatric Type 1 diabetes mellitus Omer Shaked and Daniel Hamiel 19. Empirically supported cognitive-behavioral interventions for adolescent anorexia and bulimia nervosa Madelyn Johnson, Kathryn M. Huryk, Sasha Gorrell, and Daniel Le Grange 20. Inflammatory bowel disease and cognitive behavioral therapy (CBT) in the young L. Stapersma, J.C. Escher, and E.M.W.J. Utens 21. Pediatric obsessive-compulsive disorder, CBT, and fear extinction learning Abigail E. Candelari, Daniel A. Geller, and Eric A. Storch 22. Parent-child interactions and cognitive behavioral therapy: A focus on anxious children Daniëlle Van der Giessen and Francisca J.A. Van Steensel 23. Standard individual cognitive behavioral therapy for children and adolescents with pediatric obsessive-compulsive disorder Gudmundur Skarphedinsson, Davíð R.M.A. Højgaard, Katja Anna Hybel, Per Hove Thomsen, and Tord Ivarsson 24. Obsessive-compulsive disorder and body dysmorphic disorder: Pediatric manifestation and treatment Matthew Jacofsky, Madison Fitzpatrick, and Fugen Neziroglu 25. Cognitive behavior therapy for children with depression: Application, practical considerations, and challenges Tushar Singh, Debasruti Ghosh, Thomas Enias Pasipanodya, Saurabh Raj, and Shalini Mittal Section C. Aging, the elderly and related conditions 26. Cognitive-behavioral therapy for late-life insomnia Joseph M. Dzierzewski, Elliottnell Perez, Pablo Soto, and Scott G. Ravyts 27. Brief cognitive behavioral therapy for insomnia in community dwelling older adults Mika Tanaka and Katsutoshi Tanaka 28. Dementia: Features of treating anxiety and depression and the role of cognitive behavioral therapy: A new narrative Kok-Wai Tay and Ponnusamy Subramaniam 29. The elderly and fear of falling: Features and applications of cognitive-behavioral therapy Tai Wa Liu and Shamay S.M. Ng Section D. International aspects 30. Cognitive-behavioral therapy for children with anxiety in Japan: Bidirectional cultural adaptation and cross-cultural comparison studies Shin-ichi Ishikawa 31. Adolescent depression and cognitive behavior therapy: Indian aspects Paakhi Srivastava, Pragya Sharma, Ananya Mahapatra, and Samridhi Ahuja 32. Khat chewing and cognitive behavioral therapy Abdifatah Haji Daud, Zahid Mahmood, and Yakoub Aw Aden Abdi 33. CBT for anxiety disorders among children in Pakistan Anowra Khan and Tamkeen Ashraf Malik Section E. Case studies and resources 34. "I am so much more than OCD": A case illustration of key elements in a Danish group-based CBT program for youth with OCD Katja Anna Hybel, Sanne Jensen, and Davíð R.M.A. Højgaard 35. CASE STUDY: A child with body dysmorphic disorder and cognitive-behavioral therapy Danielle H. Gardini, Yvette Fruchter, and Fugen Neziroglu 36. Case study: A child with obsessive compulsive disorder and cognitive-behavioral therapy Yvette Fruchter, Danielle H. Gardini, and Fugen Neziroglu 37. Case study. Cognitive-behavioral therapy for nightmare disorder in a youth with comorbid autism spectrum disorder Lisa D. Cromer, Devin R. Barlaan, Kristi Pruiksma, Joanne L. Davis, and Tara R. Buck 38. New cognitive-behavioral intervention with Theory of Mind (ToM) training for children with epilepsy experiencing social difficulties Elizabeth Stewart and Suncica Lah 39. Cognitive behavioral therapy and death anxiety: A case of children in conflict settings during the COVID-19 pandemic Pegah AM Seidi and Dilshad Jaff 40. Children with academic difficulties and emotional problems: Use of cognitive behavior therapy Susmita Halder and Akash Kumar Mahato 41. Case study: Cognitive behavioral therapy for postnatal depression Mariana Branquinho, Verónica Martínez-Borba, and Ana Fonseca 42. Case study: Cognitive behavioral therapy for adolescent skin picking disorder Andrea Pozza 43. Pediatric type 1 diabetes CBT intervention in fear of hypoglycemia: Case study Omer Shaked and Daniel Hamiel 44. Recommended resources for cognitive-behavioral therapy across the lifespan Rajkumar Rajendram, Vinood B. Patel, and Victor R. Preedy

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Book SynopsisTable of ContentsAnatomy and organisation of the body Physiological chemistry and processes Cells and tissues The Blood The Cardiovascular System The Lymphatic System The Nervous System The Special Senses The Endocrine System The Respiratory System Introduction to nutrition The Digestive System The Urinary System The Skin Resistance and Immunity The Musculoskeletal System Introduction to Genetics The Reproductive Systems Answers

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Book SynopsisA guided tour through the strange science of hormones and the age-old quest to control them.Trade Review"A rollicking history certain to get your intellectual and physiologic juices flowing. Adrenaline-tinged tales and hot flashes of history—just what the doctor ordered." -- Lisa Sanders, Diagnosis columnist - New York Times Magazine"A sweeping, glorious story of hormones, threaded through with sex, suffering, neurology, biology, medicine and self-discovery, Randi Hutter Epstein’s book manages to excite the imagination as well as calm it. The story is grippingly told, and Epstein manages to bring a whole system of science alive to her reading public." -- Siddhartha Mukherjee"Hormones may be ringmasters of the bodily circus, controlling everything from sex to metabolic function, but in this invigorating history they become stars of the show." -- Nature"Congratulations to my friend @randihepstein on the publication of her book! I loved reading it and highly recommend it to anyone interested in public health or your own health!" -- Chelsea Clinton"I’m hitting up the public library for two. The first is Randi Hutter Epstein’s Aroused: The history of hormones and how they control just about everything (Norton), which I hope will answer the most banal of questions as I continue my reluctant march through midlife: What the hell is happening to me?" -- Jennie Erin Smith, Summer Books 2018 - Times Literary Supplement"The field of endocrinology, as this compelling history shows, has manifested extremes of ingenuity and hubristic error." -- The New Yorker"A well-written and informative book on the history of hormone research." -- The New York Times Book Review"Here, a leading medical writer and professor at Yale University uncovers the true science of hormones and looks back into the basements, labs and back rooms where the study of endocrinology began." -- What to Read - Mail on Sunday

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Book SynopsisTable of Contents1 Cells, Tissues and Organs 2 Thorax (Chest) 3 Vertebral Column (Back) 4 Head and Neck 5 Upper Limb 6 Abdomen, Pelvis and Perineum 7 Lower Limb APPENDIX A Answers to Self-Test Questions Index

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Book SynopsisAdam Wilkins draws on studies of nonhuman species, the fossil record, genetics, and molecular and developmental biology to reconstruct the evolution of the human face and its inextricable link to our species' evolving social complexity. The neural and muscular mechanisms that allowed facial expressions also led to speech, which is unique to humans.Trade ReviewMaking Faces makes faces fascinating by opening a window onto an intriguing biological landscape. Lucid accounts of the roles played by genes, bones, muscle, and brain foreshadow provocative questions about race, sex, and psychology. Wilkins’s elegant account is a guide not only to what we see in the mirror, but also to the latest and the best in human evolution. -- Richard Wrangham, author of Catching Fire: How Cooking Made Us HumanMaking Faces is a highly readable account of how and why the human face is the way it is. Wilkins lucidly weaves together over a century of research on the development, anatomy, and evolution with new provocative ideas. -- Daniel E. Lieberman, author of The Evolution of the Human HeadTracing our evolutionary history back to the emergence of the first vertebrates some 500 million years ago, Wilkins pairs biological and genetic studies with the archaeological record to examine how humans developed the most expressive faces in the animal kingdom. It was an intriguing transformation that also provided the foundation for someof our species’ unique characteristics, including the neural and muscular mechanisms necessary for speech, the cognitive ability to interpret emotional responses, and thereby sociability and culture. The book…gives a truly fresh appreciation of the wonders of the human face—even if they are still lost on us first thing in the morning. -- Nicholas Bartos * Current World Archaeology *This engaging and highly readable book offers a lucid account of the diverse areas of ‘scientific investigation’ that have shaped contemporary understanding of the evolution of the human face…[It] will appeal to any individual with an interest in human evolution and biology. -- T. Harrison * Choice *

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Book SynopsisTried and true - build A&P confidence every step of the way! Here's the approach that makes A&P easier to master. A student-friendly writing style, superb art program, and learning opportunities in every chapter build a firm foundation in this must-know subject to ensure success.Table of Contents Chapter 1 Organization and General Plan of the Body Chapter 2 Some Basic Chemistry Chapter 3 Cells Chapter 4 Tissues and Membranes Chapter 5 The Integumentary System Chapter 6 The Skeletal System Chapter 7 The Muscular System Chapter 8 The Nervous System Chapter 9 The Senses Chapter 10 The Endocrine System Chapter 11 Blood Chapter 12 The Heart Chapter 13 The Vascular System Chapter 14 The Lymphatic System and Immunity Chapter 15 The Respiratory System Chapter 16 The Digestive System Chapter 17 Body Temperature and Metabolism Chapter 18 The Urinary System Chapter 19 Fluid-Electrolyte and Acid-Base Balance Chapter 20 The Reproductive Systems Chapter 21 Human Development and Genetics Chapter 22 An Introduction to Microbiology and Human Disease Appendices Glossary Index

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Book SynopsisThis practical manual promotes an evidence-based paradigm of fetal heart rate monitoring during labour, moving away from the traditional 'pattern-based' interpretation to physiology-based interpretation. Aimed at obstetricians and midwives, it is useful to all those involved in multiprofessional intrapartum care.Table of ContentsList of contributors; Preface; Acknowledgment; Glossary; 1. 'An eye opener': perils of CTG misinterpretation. Lessons from confidential enquiries and medico-legal cases Edwin Chandraharan; 2. Physiology of fetal heart rate control and types of intrapartum hypoxia Anna Gracia-Perez-Bonfils and Edwin Chandraharan; 3. Fetal oxygenation Anna Gracia Perez-Bonfils and Edwin Chandraharan; 4. Understanding the CTG: technical aspects Harriet Stevenson and Edwin Chandraharan; 5. Applying fetal physiology to interpret CTG traces: predicting the NEXT change Edwin Chandraharan; 6. Avoiding errors: maternal heart rate Sophie Eleanor Kay and Edwin Chandraharan; 7. Antenatal cardiotocography Amar Bhide and Francesco D'Antonio; 8. Intermittent (intelligent) auscultation in the low risk setting Virginia Lowe and Abigail Archer; 9. Current scientific evidence on CTG Ana Piñas Carrillo and Edwin Chandraharan; 10. Role of uterine contractions and intrapartum re-oxygenation ratio Sadia Muhammad and Edwin Chandraharan; 11. Intrapartum monitoring of a preterm fetus Ana Piñas Carrillo and Edwin Chandraharan; 12. Role of chorioamnionitis and infection Jessica Moore and Edwin Chandraharan; 13. Meconium: why is it harmful? Leonie Penna; 14. Intrapartum bleeding Edwin Chandraharan; 15. Labour with a uterine scar: the role of CTG Ana Piñas Carrillo and Edwin Chandraharan; 16. Impact of maternal environment on fetal heart rate Ayona Wijemanne and Edwin Chandraharan; 17. Use of CTG with induction and augmentation of labour Ana Piñas Carrillo and Edwin Chandraharan; 18. Recognition of chronic hypoxia and the preterminal cardiotocograph Austin Ugwumadu; 19. Unusual fetal heart rate patterns: sinusoidal and saltatory patterns Madhusree Ghosh and Edwin Chandraharan; 20. Intrauterine resuscitation Abigail Spring and Edwin Chandraharan; 21. Management of prolonged decelerations and bradycardia Rosemary Townsend and Edwin Chandraharan; 22. ST-Analyser: case examples and pitfalls Sabrina Kuah and Geoff Matthews; 23. Role of a computerised CTG Sabrina Kuah and Geoff Matthews; 24. Peripheral tests of fetal wellbeing Charis Mills and Edwin Chandraharan; 25. ST-Analyser (STAN): principles and physiology Ana Piñas Carrillo and Edwin Chandraharan; 26. Operative interventions for fetal compromise Mary Catherine Tolcher and Kyle D. Traynor; 27. Non hypoxic causes of CTG changes Dovilė Kalvinskaitė and Edwin Chandraharan; 28. Neonatal implications of intrapartum fetal hypoxia Justin Richards; 29. Role of the anaesthetist in the management of fetal compromise during labour Anuji Amarasekara and Anthony Addei; 30. Medico-legal issues with CTG K. Muhunthan and Sabaratnam Arulkumaran; 31. Ensuring competency in intrapartum fetal monitoring: the role of GIMS Virginia Lowe and Edwin Chandraharan; 32. Physiology-based CTG training: does it really matter? Sara Ledger and Edwin Chandraharan; Index.

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Book SynopsisTable of ContentsForeword xix Acknowledgments xxi Abbreviations xxiii Book Navigation xxix Part I Understanding Cell Culture 1 1. Introduction 3 1.1 Terminology 3 1.2 Historical Development 4 1.3 Applications 12 1.4 Advantages of Tissue Culture 13 1.5 Limitations of Tissue Culture 15 References 18 2. Biology of Cultured Cells 23 2.1 The Culture Environment 23 2.2 Cell Adhesion 23 2.3 Cell Division 28 2.4 Cell Fate 30 2.5 Cell Death 35 References 36 3. Origin and Evolution of Cultured Cells 39 3.1 Origin of Cultured Cells 39 3.2 Evolution of Cell Lines 40 3.3 Changes in Genotype 43 3.4 Changes in Phenotype 46 3.5 Senescence and Immortalization 48 Minireview M3.1 Senescence and Immortalization 48 3.6 Transformation 50 3.7 Conclusions: Origin and Evolution 58 References 58 Part II Laboratory and Regulatory Requirements 63 4. Laboratory Design and Layout 65 4.1 Design Requirements 65 4.2 Layout of Laboratory Areas 74 4.3 Disaster and Contingency Planning 80 References 83 5. Equipment and Materials 85 5.1 Sterile Handling Area Equipment 85 5.2 Imaging and Analysis Equipment 97 5.3 Incubation Equipment 99 5.4 Preparation and Washup Equipment 104 5.5 Cold Storage Equipment 107 References 109 6. Safety and Bioethics 111 6.1 Laboratory Safety 111 6.2 Hazards in Tissue Culture Laboratories 117 6.3 Biosafety 121 6.4 Bioethics 129 References 132 7. Reproducibility and Good Cell Culture Practice 137 7.1 Reproducibility 137 7.2 Good Practice Requirements 141 7.3 Cell Line Provenance 145 7.4 Validation Testing 146 7.5 Quality Assurance (QA) 148 7.6 Replicate Sampling 150 References 151 Part III Medium and Substrate Requirements 155 8. Culture Vessels and Substrates 157 8.1 Attachment and Growth Requirements 157 8.2 Substrate Materials 158 8.3 Substrate Treatments 159 8.4 Feeder Layers 163 8.5 Choice of Culture Vessel 164 8.6 Application-Specific Vessels 170 References 173 9. Defined Media and Supplements 177 9.1 Medium Development 177 9.2 Physicochemical Properties 177 9.3 Balanced Salt Solutions 185 9.4 Media Formulations 186 9.5 Serum 189 9.6 Other Media Supplements 191 9.7 Choice of Complete Medium 191 9.8 Storage of Medium and Serum 194 Suppliers 194 References 194 10. Serum-Free Media 199 10.1 Rationale for Serum-Free Medium 199 10.2 Development of Serum-Free Medium 201 10.3 Serum-Free Media Formulations 202 10.4 Serum-Free Supplements 203 10.5 Serum Replacements 209 10.6 Use of Serum-Free Medium 209 10.7 Xeno-Free Media 213 10.8 Animal Product-Free Media 214 10.9 Conclusions: Serum-Free Media 214 Suppliers 214 References 215 11. Preparation and Sterilization 219 11.1 Terminology: Preparation 219 11.2 Sterilization Methods 220 11.3 Glassware 224 Protocol P11.1 Preparation and Sterilization of Glassware 224 11.4 Other Laboratory Apparatus 229 11.5 Water 229 11.6 Media and Other Reagents 233 11.7 Sterile Filtration 238 11.8 Medium Testing 242 Suppliers 247 References 247 Part IV Handling Cultures 249 12. Aseptic Technique 251 12.1 Objectives of Aseptic Technique 251 12.2 Elements of Aseptic Environment 252 12.3 Sterile Handling 258 12.4 Good Aseptic Technique 260 12.5 Controlling Equipment Contamination 265 Suppliers 267 References 267 13. Primary Culture 269 13.1 Rationale for Primary Culture 269 13.2 Initiation of Primary Culture 270 13.3 Tissue Acquisition and Isolation 274 13.4 Primary Explantation 281 Protocol P13.3 Culture of Primary Explants 281 13.5 Enzymatic Disaggregation 283 13.6 Mechanical Disaggregation 290 Protocol P13.7 Mechanical Disaggregation by Sieving 291 13.7 Enrichment of Viable Cells 292 Protocol P13.8 Enrichment of Viable Cells 292 13.8 Record Keeping for Primary Culture 293 13.9 Conclusions: Primary Culture 294 Suppliers 294 References 294 14. Subculture and Cell Lines 297 14.1 Terminology: Cell Line and Subculture 297 14.2 Initiating a Cell Line 298 14.3 Choosing a Cell Line 300 14.4 Maintaining a Cell Line 304 14.5 Replacing Medium (Feeding) 309 14.6 Subculture (Passaging) 312 14.7 Maintaining Suspension Cultures 320 14.8 Serum-Free Subculture 322 14.9 Record Keeping for Cell Lines 323 Suppliers 324 References 325 15. Cryopreservation and Banking 327 15.1 Principles of Cryopreservation 327 15.2 Apparatus for Cryopreservation 329 15.3 Requirements for Cryopreservation 335 15.4 Cryopreservation Procedures 336 15.5 Cell Banking Procedures 341 15.6 Cell Repositories 342 15.7 Record Keeping for Frozen Stocks 345 15.8 Transporting Cells 347 Suppliers 348 References 348 Part V Validation and Characterization 351 16. Microbial Contamination 353 16.1 Sources of Contamination 353 16.2 Management of Contamination 359 Protocol P16.1 Disposal of Contaminated Cultures 360 16.3 Visible Microbial Contamination 361 16.4 Mycoplasma Contamination 364 16.5 Viral Contamination 373 16.6 Dealing with Persistent Contamination 376 Suppliers 376 References 376 17. Cell Line Misidentification and Authentication 381 17.1 Terminology: Cross-Contamination, Misidentification, and Authentication 381 17.2 Misidentified Cell Lines 382 17.3 Cell Line Authentication 386 17.4 Authentication of Challenging Samples 401 17.5 Conclusions: Authentication 403 Suppliers 403 References 403 18. Cell Line Characterization 409 18.1 Priorities and Essential Characterization 409 18.2 Genotype-Based Characterization 416 18.3 Phenotype-Based Characterization 419 18.4 Cell Imaging 423 18.5 Cell Staining 428 Suppliers 430 References 430 19. Quantitation and Growth Kinetics 437 19.1 Cell Counting 437 19.3 Cell Proliferation 450 19.4 Cloning Efficiency 456 19.5 DNA Synthesis 460 19.6 Cell Cycle Analysis 461 Suppliers 461 References 461 Part VI Physical and Genetic Manipulation 465 20. Cell Cloning and Selection 467 20.1 Terminology: Cloning and Selection 467 20.2 Cloning by Limiting Dilution 468 20.3 Cloning in Suspension 473 20.4 Selection of Clones 477 20.5 Replica Plating 480 20.6 Stimulation of Cloning Efficiency 481 20.7 Selective Culture Conditions 485 20.8 Conclusions: Cloning and Selection 487 Suppliers 487 References 487 21. Cell Separation and Sorting 491 21.1 Cell Density and Isopycnic Centrifugation 491 21.2 Cell Size and Sedimentation Velocity 495 21.3 Magnetic Separation and Sorting 496 Protocol P21.2 Magnet-Activated Cell Sorting (MACS) 499 21.4 Fluorescence-Activated Cell Sorting (FACS) 500 21.5 Microfluidic Sorting 502 Minireview M21.1 Microfluidic Cell Culture 503 21.6 Conclusions: Sorting and Separation 505 Suppliers 505 References 505 22. Genetic Modification and Immortalization 509 22.1 Gene Delivery 509 22.2 Gene Editing 517 22.3 Immortalization 523 22.4 Screening and Artifacts 526 Suppliers 528 References 528 Part VII Stem Cells and Differentiated Cells 535 23. Culture of Stem Cells 537 23.1 Terminology: Stem Cells 537 23.2 Embryonic Stem Cells (ESCs) 540 23.3 Induction of Pluripotency 545 Protocol P23.1 Generation of iPSCs Using Sendai Viral Vectors 547 23.4 Human Pluripotent Stem Cell (hPSC) Lines 549 23.5 Perinatal Stem Cells 556 23.6 Adult Stem Cells 557 23.7 Stem Cell Characterization and Banking 558 23.8 Conclusions: Culture of Stem Cells 560 Suppliers 561 References 561 24. Culture of Specific Cell Types 567 24.1 Specialized Cells and Their Availability 567 24.2 Epithelial Cells 572 24.3 Mesenchymal Cells 577 24.4 Neuroectodermal Cells 580 24.5 Hematopoietic Cells 581 24.6 Culture of Cells from Poikilotherms 585 Suppliers 587 References 587 25. Culture of Tumor Cells 593 25.1 Challenges of Tumor Cell Culture 593 25.2 Primary Culture of Tumor Cells 594 25.3 Development of Tumor Cell Lines 596 25.4 Selective Culture of Tumor Cells 599 25.5 Specific Tumor Types 603 25.6 Cancer Stem Cells (CSCs) 606 Minireview M25.1 Culture of Cancer Stem Cells 606 Suppliers 608 References 608 26. Differentiation 615 26.1 In Vitro Models of Differentiation 615 26.2 Differentiation Status in Culture 617 26.3 Induction of Differentiation 620 26.4 Practical Aspects 628 26.5 Ongoing Challenges 629 Suppliers 631 References 631 Part VIII Model Environments and Applications 639 27. Three-Dimensional Culture 641 27.1 Terminology: 3D Culture 641 27.2 Technologies for 3D Culture 643 Minireview M27.1 Advances in Technologies Enabling 3D Cell Culture and the Formation of Tissue-Like Architecture In Vitro 643 27.3 Benefits and Limitations of 3D Culture 646 27.4 Scaffold-Free 3D Culture Systems 647 27.5 Scaffold-Based 3D Culture Systems 652 27.6 Organoid Culture 659 27.7 Organotypic Culture 660 27.8 Organ Culture 662 27.9 Characterization of 3D Cultures 662 Suppliers 663 References 663 28. Scale-Up and Automation 669 28.1 Terminology: Scale-Up and Bioreactors 669 28.2 Scale-Up in Suspension 671 28.3 Scale-Up in Monolayer 677 28.4 Monitoring and Process Control 685 28.5 Scale-Up for Manufacture 688 Minireview M28.1 Culture Scale-Up and Bioreactors 688 28.6 High-Throughput Screening 691 28.7 Automation and Bioprinting 691 Suppliers 696 References 696 29. Toxicity Testing 701 29.1 In Vitro Toxicity Testing 701 29.2 Cytotoxicity Assays 704 29.3 Genotoxicity Assays 715 29.4 Carcinogenicity Assays 716 29.5 Advanced Models for Toxicity Testing 716 Suppliers 719 References 719 Part IX Teaching and Troubleshooting 725 30. Training 727 30.1 Training Principles 727 30.2 Training Programs 729 References 731 31. Problem Solving 733 31.1 Microbial Contamination 733 31.2 Cross-Contamination and Misidentification 737 31.3 Chemical Contamination 738 31.4 Slow Cell Growth 738 31.5 Abnormal Cell Appearance 740 31.6 Problems with Materials 741 31.7 Problems with Primary Culture 744 31.8 Problems with Feeding or Subculture 746 31.9 Problems with Cryopreservation 748 31.10 Problems with Cloning 750 References 752 32. In Conclusion 753 Appendix A Glossary 755 Appendix B Calculations and Preparation of Reagents 761 Calculations 761 Counting Cells with a Hemocytometer 761 Dilution of a Cell Suspension 761 Population Doubling Level (PDL) 761 Molarity 762 Percentages and Dilutions 762 Pressure 762 Rotor Speed (rpm to g) 762 Preparation of Reagents 762 Acetic Acid: Methanol 762 Agar (2.5%) 762 Alcohol (70%) 762 Bacto™ Peptone (5%) 763 Balanced Salt Solutions 763 Carboxymethylcellulose (CMC; 4%) 763 Chick Embryo Extract 763 Collagenase 763 Collection Medium 763 Crystal Violet (0.1%) 764 Dexamethasone (1 mg/ml) 764 Dissection Balanced Salt Solution (DBSS) 764 Dulbecco’s Phosphate-Buffered Saline Without Ca2+ and Mg2+ (DPBS-A) 764 EDTA (10 mM in DPBS-A) 764 EGTA 764 Erythrosin B 764 Gelatin (1%) 765 Giemsa Stain 765 Glucose (20%) 765 Glutamine 200 mM 765 Hanks’s Balanced Salt Solution (HBSS) 765 HAT Medium 765 HB Medium 765 HEPES 765 Hoechst 33258 766 Media 766 2-Mercaptoethanol (𝛽-Mercaptoethanol; 0.1 M) 766 Methylcellulose (Methocel, 1.6%) 766 Mitomycin C (100 μg/ml) 766 MTT (50 mg/ml) 766 N2 Supplement 766 N2B27 Medium 767 Naphthalene Black (Amido Black; 1%) 767 Non-essential Amino Acids (NEAA, 100×) 767 Paraformaldehyde (4%) 767 Trypan Blue (0.4%) 767 Trypsin (2.5%) 768 Versene 768 Suppliers 768 References 768 Appendix C Media Formulations 769 References 779 Index 781

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Book SynopsisThe best review of renal physiology available for USMLE Step 1âcompletely updated with the latest researchCombining the latest research with a fully integrated teaching approach, Vanderâs Renal Physiology, Tenth Edition clearly and expertly explains how the kidneys affect other body systems and how they in turn are affected by these systems. There is no better way to learn the fundamental principles of the structure, function, and pathologies of the human kidney that are essential for an understanding of clinical medicine, than this time-tested resource.Hereâs why Vanderâs is the best review of renal physiology available for the USMLE Step 1: The text begins with the basics and works up to advanced principles All chapters have been revised to reflect the latest research and developments in the field Includes learning aids such as flow charts, diagrams, key concepts, clinical examples, boxed statements to emphasize major

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Book SynopsisThe thoroughly revised edition of Vander's Human Physiology is an integrated package of textual and digital material that delivers basic and clinical content, real-life applications, and educational technologies. All these pieces come together to facilitate learning and enthusiasm for understanding the mechanisms of body function. Key focus areas include homeostasis, exercise, and human health. These and other areas of interest are elaborated upon, beginning with Chapter 1, where the key General Principles of Physiology, an underlying theme in the book, is first introduced. Unifying themes, such as homeostasis, are explored throughout the book at all levels of system, organ, tissue, and cellular functionthemes that are always related to pathophysiology through the use of compelling clinical case studies in all chapters, and a final chapter with several cases that integrate material across the entire book. Table of ContentsChapter 1 Homeostasis: A Framework for Human Physiology Chapter 2 Chemical Composition of the Body and Its Relation to PhysiologyChapter 3 Cellular Structure, Proteins, and Metabolic PathwaysChapter 4 Movement of Solutes and Water Across Cell MembranesChapter 5 Cell Signaling in PhysiologyChapter 6 Neuronal Signaling and the Structure of the Nervous SystemChapter 7 Sensory Physiology Chapter 8 Consciousness, the Brain, and Behavior Chapter 9 Muscle Chapter 10 Control of Body Movement Chapter 11 The Endocrine System Chapter 12 Cardiovascular Physiology Chapter 13 Respiratory Physiology Chapter 14 The Kidneys and Regulation of Water and Inorganic Ions Chapter 15 The Digestion and Absorption of Food Chapter 16 Regulation of Organic Metabolism and Energy Balance Chapter 17 Reproduction Chapter 18 The Immune SystemChapter 19 Medical Physiology: Integration Using Clinical Cases

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Book SynopsisAnatomy & Physiology: The Unity of Form and Function tells a story comprised of many layers, including core science, clinical applications, the history of medicine, and evolution of the human body. Saladin combines this humanistic perspective on anatomy and physiology with vibrant photos and art to convey the beauty and excitement of the subject. To help students manage the tremendous amount of information in this introductory course, the narrative is broken into short segments, each framed by expected learning outcomes and self-testing review questions.Table of ContentsPART ONE- ORGANIZATION OF THE BODY1 Major Themes of Anatomy and Physiology -ATLAS A General Orientation to Human Anatomy2 The Chemistry of Life3 Cellular Form and Function4 Genes and Cellular Function5 The Human Tissues PART TWO- SUPPORT AND MOVEMENT 6 The Integumentary System 7 Bone Tissue8 The Skeletal System9 Joints10 The Muscular System -ATLAS B Regional and Surface Anatomy 11 Muscular Tissue PART THREE- INTERNAL COORDINATION AND CONTROL12 Nervous Tissue 13 The Spinal Cord, Spinal Nerves, and Somatic Reflexes 14 The Brain and Cranial Nerves15 The Autonomic Nervous System and Visceral Reflexes 16 Sense Organs 17 The Endocrine SystemPART FOUR- CIRCULATION AND DEFENSE18 The Circulatory System: Blood19 The Circulatory System: Heart 20 The Circulatory System: Blood Vessels and Circulation21 The Lymphoid and Immune SystemsPART FIVE- INTAKE AND OUTPUT 22 The Respiratory System 23 The Urinary System 24 Fluid, Electrolyte, and Acid–Base Balance25 The Digestive System 26 Nutrition and MetabolismPART SIX-REPRODUCTION AND THE LIFE CYCLE27 The Male Reproductive System 28 The Female Reproductive System 29 Human Development and Aging APPENDIX A: Answer Keys APPENDIX B: Symbols, Weights, and Measures APPENDIX C: Periodic Table of the Elements APPENDIX D: The Genetic Code and Amino Acids APPENDIX E: Medical Word Roots and Affixes

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Book SynopsisDesigned for the one-semester anatomy and physiology course, Hole''s Essentials of Human Anatomy and Physiology assumes no prior science knowledge and supports core topics with clinical applications, making difficult concepts relevant to students pursuing careers in the allied health field. The Learn, Practice, and Assess system is used throughout the text and digital content for immediate application. Learning outcomes begin the chapter and set the stage for what students will learn, Practice questions conclude each major section and help students recall the information they've consumed, and Assess end-of-chapter resources allow students to confirm their accurate recall of what they learned and practiced. The learn, practice, and assess system is highly effective in providing students with a solid understanding of the important concepts in anatomy and physiology.Table of ContentsUNIT 1- LEVELS OF ORGANIZATION1. Introduction to Human Anatomy and Physiology 2. Chemical Basis of Life 3. Cells 4. Cellular Metabolism5. TissuesUNIT 2- SUPPORT AND MOVEMENT6. Integumentary System7. Skeletal System8. Muscular SystemUNIT 3- INTEGRATION AND COORDINATION9. Nervous System10. The Senses11. Endocrine SystemUNIT 4- TRANSPORT12. Blood13. Cardiovascular System14. Lymphatic System and ImmunityUNIT 5- ABSORPTION AND EXCRETION15. Digestive System and Nutrition16. Respiratory System17. Urinary System 18. Water, Electrolyte, and Acid-Base BalanceUNIT 6- THE HUMAN LIFE CYCLE19. Reproductive Systems20. Pregnancy, Growth, Development, and Genetics

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Book SynopsisFrom cell chemistry to the respiratory system, Anatomy 101 is packed with hundreds of entertaining facts that you can't get anywhere else!

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Book SynopsisWritten by experts in the field, Advanced Exercise Physiology: Essential Concepts and Applications builds upon foundational topics and looks further into key physiological components to help advanced students gain a deeper level of understanding.Table of ContentsChapter 1. Exercise Metabolism Chapter 2. Dynamics of Skeletal-Neuromuscular and Gastrointestinal Physiology Chapter 3. Cardiovascular System: Function and Control Chapter 4. Pulmonary Exercise Physiology Chapter 5. Immune and Endocrine System Chapter 6. Principles for Testing and Training for Aerobic Power Chapter 7. Principles for Testing and Training Anaerobic Strength, Power, and Range of Motion Chapter 8. Body Composition and Weight Management Chapter 9. Performance: Environmental Stressors, Genetics, Nutrition, and Ergogenic Aids Chapter 10. Physical Activity and Exercise for Health and Fitness Chapter 11. Emerging Concepts: Exercise Pharmacology and Exercise Genomics Appendix A. Calculations for Oxygen Consumption and Carbon Dioxide Production Appendix B. Efficiency and Energy Expenditure Appendix C. Metabolic Equivalent of Task Values of Common Activities Appendix D. Professionalization of the Exercise Professional Appendix E. Common Scientific Abbreviations and Units

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Book SynopsisA comprehensive course in the power of energy medicine—drawing on polarity therapy, esoteric anatomy, and somatics—that reveals the vital role of consciousness in the healing arts   Esoteric Anatomy offers a spiritual approach to massage, bodywork, and somatic psychology, demystifying an ancient transpersonal model for understanding energy in nature and working with consciousness in the healing arts. It offers a comprehensive health care system based on understanding the body as a field of conscious energy—a system that promotes healing, health building, and self-actualization.   Author and spiritual healer Bruce Burger begins by introducing Polarity Therapy in a series of energy-balancing sessions that can be used in conjunction with other forms of therapy and bodywork. This holistic approach can alleviate physical, mental, emotional, and spiritual suffering, including clearing trauma from the cellular memory of the brain. Next, he turns his attention to Esoteric Anatomy in a section of essays that explore the role of energy—or life force—in the healing arts, drawing from the wisdom of ancient India. And finally, Burger builds upon his studies of Polarity Therapy and Esoteric Anatomy to present a unique system of Somatic Psychology that can promote further healing.   Thorough, insightful, and complete with illustrations, Esoteric Anatomy is a fascinating course in energy medicine that can guide you toward better health, personal growth, and spiritual transformation.

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Book SynopsisThis is the loose-leaf version of Physiology of Sport and Exercise, Eighth Edition With HKPropel Access, which offers students a less expensive printed version of the text.Physiology of Sport and Exercise, Eighth Edition With HKPropel Access, continues its legacy as a top physiology textbook and favorite of instructors and students alike. Combining research with extensive visual aids, this resource offers a simple way for students to explore the body’s response to various types and intensities of exercise and sports. Written by a team of distinguished researchers, all past presidents of the American College of Sports Medicine, this eighth edition has been updated based on the most recent standards and guidelines in the field of exercise physiology. The text builds upon the previous edition’s high standards for illustrations, photos, and medical artwork with a refreshed, more sophisticated look to encourage a deep understanding of complex topics. Related multimedia components delivered through HKPropel further enrich the learning experience with 26 animations that offer a dynamic way to experience physiological concepts and 66 audio clips that offer explanations of elaborate physiological processes. Leaders in the field help students connect theoretical and practical concepts in 27 video clips. Various types of online learning activities, key term flash card reviews, and key term quizzes offer interactive opportunities to engage with the content—all of which can be assigned, and progress tracked, by instructors directly through HKPropel. In addition, chapter quizzes (assessments) may also be assigned; these are automatically graded to test comprehension of critical concepts. QR codes throughout the text notify students when complementary digital components are available.Physiology of Sport and Exercise, Eighth Edition, features the following enhancements based on the latest research in the field: Additional information on cellular signaling and molecular adaptations Expanded content on obesity and sports nutrition Reorganized and expanded chapters on energy expenditure and exercise prescription that make the content more accessible to students Extensive updates on important topics, including bioinformatics and big data, reading research articles, molecular mechanisms of increased protein synthesis, muscle cramps, and mitochondrial oxidation Updated Research Perspective sidebars that emphasize emerging findings in the field and a Research Perspectives Finder to help students locate key content quickly As in previous editions, readability and ease of understanding make Physiology of Sport and Exercise different from other physiology resources. Unique learning aids, including chapter-opening outlines and review boxes throughout each chapter, will help students focus on the major concepts addressed. Study questions and a list of key terms at the end of each chapter provide opportunities for recall and self-assessment. A comprehensive glossary and lists of common abbreviations and conversions provide easy reference for students.Physiology of Sport and Exercise has been a pivotal textbook in the field of exercise physiology. Through this edition’s dynamic and interactive learning activities, easy-to-follow layouts, and research-oriented content enriched with visual supplements, students and instructors will find this an invaluable resource for their continued education. Note: A code for accessing HKPropel is included with all new print books.Table of ContentsResearch Perspectives FinderIntroduction. An Introduction to Exercise and Sport Physiology Focus of Exercise and Sport Physiology Acute and Chronic Responses to Exercise The Evolution of Exercise Physiology Exercise Physiology in the 21st Century Research: Turning Curiosity Into SciencePart I. Exercising MuscleChapter 1. Structure and Function of Exercising Muscle Anatomy of Skeletal Muscle Muscle Fiber Contraction Muscle Fiber Types Skeletal Muscle and ExerciseChapter 2. Fuel for Exercise: Bioenergetics and Muscle Metabolism Energy Substrates Controlling the Rate of Energy Production Storing Energy: High-Energy Phosphates The Basic Energy Systems Interaction of the Energy Systems The Crossover Concept The Oxidative Capacity of MuscleChapter 3. Neural Control of Exercising Muscle Structure and Function of the Nervous System Central Nervous System Peripheral Nervous System Sensory-Motor IntegrationChapter 4. Hormonal Control During Exercise The Endocrine System Endocrine Glands and Their Hormones: An Overview Hormonal Regulation of Metabolism During Exercise Hormonal Regulation of Fluid and Electrolytes During Exercise Hormonal Regulation of Caloric IntakePart II. Muscle EnergyChapter 5. Energy Expenditure Measuring Energy Expenditure Estimating Energy Expenditure Predicting Energy Expenditure Energy Expenditure at Rest and During ExerciseChapter 6. Fatigue, Muscle Soreness, and Muscle Cramps Fatigue and Its Causes Critical Power: The Link Between Energy Expenditure and Fatigue Muscle Soreness Exercise-Induced Muscle CrampsPart III. Cardiovascular and Respiratory FunctionChapter 7. The Cardiovascular System and Its Control The Heart Vascular System BloodChapter 8. The Respiratory System and Its Regulation Pulmonary Ventilation Pulmonary Volumes Pulmonary Diffusion Transport of Oxygen and Carbon Dioxide in the Blood Gas Exchange at the Muscles Regulation of Pulmonary Ventilation Afferent Feedback From Exercising Limbs Exercise Training and Respiratory FunctionChapter 9. Cardiorespiratory Responses to Acute Exercise Cardiovascular Responses to Acute Exercise Respiratory Responses to Acute Exercise Recovery From Acute ExercisePart IV. Exercise TrainingChapter 10. Principles of Exercise Training Terminology General Principles of Training Resistance Training Programs Anaerobic and Aerobic Power Training ProgramsChapter 11. Adaptations to Resistance Training Resistance Training and Gains in Muscular Fitness Mechanisms of Gains in Muscle Strength Interaction Between Resistance Training and Diet Resistance Training for Special PopulationsChapter 12. Adaptations to Aerobic and Anaerobic Training Adaptations to Aerobic Training Adaptations to Anaerobic Training Adaptations to High-Intensity Interval Training Specificity of Training and Cross-TrainingChapter 13. Prescription of Exercise for Health and Fitness Health Benefits of Regular Physical Activity and Exercise Exercise and Cognitive Function Physical Activity Recommendations Health Screening Exercise Prescription Monitoring Exercise Intensity Exercise Programming Exercise and Rehabilitation of People with DiseasesPart V. Environmental Influences on PerformanceChapter 14. Exercise in Hot and Cold Environments Body Temperature Regulation Physiological Responses to Exercise in the Heat Health Risks During Exercise in the Heat Acclimation to Exercise in the Heat Exercise in the Cold Physiological Responses to Exercise in the Cold Health Risks During Exercise in the ColdChapter 15. Altitude, Hyperbaric Environments, and Microgravity Environmental Conditions at Altitude Physiological Responses to Acute Altitude Exposure Exercise and Sport Performance at Altitude Acclimation: Chronic Exposure to Altitude Altitude: Optimizing Training and Performance Health Risks of Acute Exposure to Altitude Hyperbaric Environments MicrogravityPart VI. Optimizing Performance in SportChapter 16. Training for Sport Optimizing Training Periodization of Training Overtraining Tapering for Peak Performance DetrainingChapter 17. Nutrition, Body Composition, and Obesity Classification of Nutrients Water and Electrolyte Balance Nutrition and Athletic Performance Assessing Body Composition Body Composition, Weight, and Sport Performance Obesity Weight Loss Management Guidelines Role of Physical Activity in Weight Management and Risk ReductionChapter 18. Ergogenic Aids in Sport Researching Ergogenic Aids Ergogenic Aids with Established Evidence of Efficacy Ergogenic Aids with Emerging Evidence of Efficacy Prohibited Substances and TechniquesPart VI. Special Considerations in Sport, Exercise, and Physical ActivityChapter 19. Children and Adolescents in Sport and Exercise Growth, Development, and Maturation Physiological Responses to Acute Exercise Physiological Adaptations to Exercise Training Physical Activity Patterns Among Youth Sport Performance and Specialization Special IssuesChapter 20. Aging in Sport and Exercise Height, Weight, and Body Composition Physiological Responses to Acute Exercise Physiological Adaptations to Exercise Training Sport Performance Special IssuesChapter 21. Sex Differences in Sport and Exercise Sex Versus Gender in Exercise Physiology Body Size and Composition Physiological Responses to Acute Exercise Physiological Adaptations to Exercise Training Sport Performance Special IssuesChapter 22. Cardiovascular Disease and Physical Activity Prevalence of Cardiovascular Disease Forms of Cardiovascular Disease Understanding the Disease Process Cardiovascular Disease Risk Reducing Risk Through Physical Activity Risk of Heart Attack and Death During Exercise Exercise Training and Rehabilitation of Patients with Heart Disease

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Book SynopsisThis is the loose-leaf version of Physiology of Sport and Exercise, Eighth Edition With HKPropel Access, which offers students a less expensive printed version of the text.Physiology of Sport and Exercise, Eighth Edition With HKPropel Access, continues its legacy as a top physiology textbook and favorite of instructors and students alike. Combining research with extensive visual aids, this resource offers a simple way for students to explore the body’s response to various types and intensities of exercise and sports. Written by a team of distinguished researchers, all past presidents of the American College of Sports Medicine, this eighth edition has been updated based on the most recent standards and guidelines in the field of exercise physiology. The text builds upon the previous edition’s high standards for illustrations, photos, and medical artwork with a refreshed, more sophisticated look to encourage a deep understanding of complex topics. Related multimedia components delivered through HKPropel further enrich the learning experience with 26 animations that offer a dynamic way to experience physiological concepts and 66 audio clips that offer explanations of elaborate physiological processes. Leaders in the field help students connect theoretical and practical concepts in 27 video clips. Various types of online learning activities, key term flash card reviews, and key term quizzes offer interactive opportunities to engage with the content—all of which can be assigned, and progress tracked, by instructors directly through HKPropel. In addition, chapter quizzes (assessments) may also be assigned; these are automatically graded to test comprehension of critical concepts. QR codes throughout the text notify students when complementary digital components are available.Physiology of Sport and Exercise, Eighth Edition, features the following enhancements based on the latest research in the field: Additional information on cellular signaling and molecular adaptations Expanded content on obesity and sports nutrition Reorganized and expanded chapters on energy expenditure and exercise prescription that make the content more accessible to students Extensive updates on important topics, including bioinformatics and big data, reading research articles, molecular mechanisms of increased protein synthesis, muscle cramps, and mitochondrial oxidation Updated Research Perspective sidebars that emphasize emerging findings in the field and a Research Perspectives Finder to help students locate key content quickly As in previous editions, readability and ease of understanding make Physiology of Sport and Exercise different from other physiology resources. Unique learning aids, including chapter-opening outlines and review boxes throughout each chapter, will help students focus on the major concepts addressed. Study questions and a list of key terms at the end of each chapter provide opportunities for recall and self-assessment. A comprehensive glossary and lists of common abbreviations and conversions provide easy reference for students.Physiology of Sport and Exercise has been a pivotal textbook in the field of exercise physiology. Through this edition’s dynamic and interactive learning activities, easy-to-follow layouts, and research-oriented content enriched with visual supplements, students and instructors will find this an invaluable resource for their continued education. Note: A code for accessing HKPropel is included with all new print books.Table of ContentsResearch Perspectives FinderIntroduction. An Introduction to Exercise and Sport Physiology Focus of Exercise and Sport Physiology Acute and Chronic Responses to Exercise The Evolution of Exercise Physiology Exercise Physiology in the 21st Century Research: Turning Curiosity Into SciencePart I. Exercising MuscleChapter 1. Structure and Function of Exercising Muscle Anatomy of Skeletal Muscle Muscle Fiber Contraction Muscle Fiber Types Skeletal Muscle and ExerciseChapter 2. Fuel for Exercise: Bioenergetics and Muscle Metabolism Energy Substrates Controlling the Rate of Energy Production Storing Energy: High-Energy Phosphates The Basic Energy Systems Interaction of the Energy Systems The Crossover Concept The Oxidative Capacity of MuscleChapter 3. Neural Control of Exercising Muscle Structure and Function of the Nervous System Central Nervous System Peripheral Nervous System Sensory-Motor IntegrationChapter 4. Hormonal Control During Exercise The Endocrine System Endocrine Glands and Their Hormones: An Overview Hormonal Regulation of Metabolism During Exercise Hormonal Regulation of Fluid and Electrolytes During Exercise Hormonal Regulation of Caloric IntakePart II. Muscle EnergyChapter 5. Energy Expenditure Measuring Energy Expenditure Estimating Energy Expenditure Predicting Energy Expenditure Energy Expenditure at Rest and During ExerciseChapter 6. Fatigue, Muscle Soreness, and Muscle Cramps Fatigue and Its Causes Critical Power: The Link Between Energy Expenditure and Fatigue Muscle Soreness Exercise-Induced Muscle CrampsPart III. Cardiovascular and Respiratory FunctionChapter 7. The Cardiovascular System and Its Control The Heart Vascular System BloodChapter 8. The Respiratory System and Its Regulation Pulmonary Ventilation Pulmonary Volumes Pulmonary Diffusion Transport of Oxygen and Carbon Dioxide in the Blood Gas Exchange at the Muscles Regulation of Pulmonary Ventilation Afferent Feedback From Exercising Limbs Exercise Training and Respiratory FunctionChapter 9. Cardiorespiratory Responses to Acute Exercise Cardiovascular Responses to Acute Exercise Respiratory Responses to Acute Exercise Recovery From Acute ExercisePart IV. Exercise TrainingChapter 10. Principles of Exercise Training Terminology General Principles of Training Resistance Training Programs Anaerobic and Aerobic Power Training ProgramsChapter 11. Adaptations to Resistance Training Resistance Training and Gains in Muscular Fitness Mechanisms of Gains in Muscle Strength Interaction Between Resistance Training and Diet Resistance Training for Special PopulationsChapter 12. Adaptations to Aerobic and Anaerobic Training Adaptations to Aerobic Training Adaptations to Anaerobic Training Adaptations to High-Intensity Interval Training Specificity of Training and Cross-TrainingChapter 13. Prescription of Exercise for Health and Fitness Health Benefits of Regular Physical Activity and Exercise Exercise and Cognitive Function Physical Activity Recommendations Health Screening Exercise Prescription Monitoring Exercise Intensity Exercise Programming Exercise and Rehabilitation of People with DiseasesPart V. Environmental Influences on PerformanceChapter 14. Exercise in Hot and Cold Environments Body Temperature Regulation Physiological Responses to Exercise in the Heat Health Risks During Exercise in the Heat Acclimation to Exercise in the Heat Exercise in the Cold Physiological Responses to Exercise in the Cold Health Risks During Exercise in the ColdChapter 15. Altitude, Hyperbaric Environments, and Microgravity Environmental Conditions at Altitude Physiological Responses to Acute Altitude Exposure Exercise and Sport Performance at Altitude Acclimation: Chronic Exposure to Altitude Altitude: Optimizing Training and Performance Health Risks of Acute Exposure to Altitude Hyperbaric Environments MicrogravityPart VI. Optimizing Performance in SportChapter 16. Training for Sport Optimizing Training Periodization of Training Overtraining Tapering for Peak Performance DetrainingChapter 17. Nutrition, Body Composition, and Obesity Classification of Nutrients Water and Electrolyte Balance Nutrition and Athletic Performance Assessing Body Composition Body Composition, Weight, and Sport Performance Obesity Weight Loss Management Guidelines Role of Physical Activity in Weight Management and Risk ReductionChapter 18. Ergogenic Aids in Sport Researching Ergogenic Aids Ergogenic Aids with Established Evidence of Efficacy Ergogenic Aids with Emerging Evidence of Efficacy Prohibited Substances and TechniquesPart VI. Special Considerations in Sport, Exercise, and Physical ActivityChapter 19. Children and Adolescents in Sport and Exercise Growth, Development, and Maturation Physiological Responses to Acute Exercise Physiological Adaptations to Exercise Training Physical Activity Patterns Among Youth Sport Performance and Specialization Special IssuesChapter 20. Aging in Sport and Exercise Height, Weight, and Body Composition Physiological Responses to Acute Exercise Physiological Adaptations to Exercise Training Sport Performance Special IssuesChapter 21. Sex Differences in Sport and Exercise Sex Versus Gender in Exercise Physiology Body Size and Composition Physiological Responses to Acute Exercise Physiological Adaptations to Exercise Training Sport Performance Special IssuesChapter 22. Cardiovascular Disease and Physical Activity Prevalence of Cardiovascular Disease Forms of Cardiovascular Disease Understanding the Disease Process Cardiovascular Disease Risk Reducing Risk Through Physical Activity Risk of Heart Attack and Death During Exercise Exercise Training and Rehabilitation of Patients with Heart Disease

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