Pharmacy / dispensing Books

Book SynopsisThe eighth edition of the Palliative Care Formulary (PCF), from Pharmaceutical Press, the Royal Pharmaceutical Society's knowledgebusiness, is an essential resource for health professionals who care for patients with progressive end-stage disease.

Read more less

Book SynopsisThis book traces the evolution of the pharmacist from compounder-dispenser to advisor counselor. It explores the impact on pharmacy of broad sociologic, demographic, and economic trends and examines controversial issues such as professional versus business objectives, managed cost care, coginitive services, pharmaceutical care, and the future roles

Read more less

Book SynopsisTable of ContentsChapter 1 Introduction to pharmacology 1Ian Peate Chapter 2 How to use pharmaceutical and prescribing reference guides 15Claire Pryor and Annette Hand Chapter 3 Legal and ethical issues 33Claire Leader, Emma Senior and Deborah Flynn Chapter 4 Medicines management and the role of the healthcare provider 49Annette Hand and Carol Wills Chapter 5 Pharmacodynamics and pharmacokinetics 69Barry Hill and Jaden Allan Chapter 6 Drug formulations 91Hayley Underdown and Nicola Clipperton Chapter 7 Adverse drug reaction 111Laura Park and Michelle Mitchell Chapter 8 Analgesics 127Claire Ford and Matthew Robertson Chapter 9 Antibacterials 153Deborah Flynn Chapter 10 Medications used in the cardiovascular system 187Jan Guerin and Cecilia Mihaila Chapter 11 Medications and the renal system 225Sadie Diamond‐Fox and Alexandra Gatehouse Chapter 12 Medications and diabetes mellitus 285Anne Phillips Chapter 13 Medications and the respiratory system 313Sadie Diamond‐Fox and Alexandra Gatehouse Chapter 14 Medications and the gastrointestinal system 369David Waters and Ian Naldrett Chapter 15 Medications used in cancer 389Elaine Walls and Leah Rosengarten Chapter 16 Medications and the nervous system 415Julie Derbyshire Chapter 17 Medications used in mental health 437Laura Stavert Chapter 18 Immunisations 465Aby Mitchell Normal Values 491 Answers 495 Index 49

Read more less

Book SynopsisNurses! Test Yourself in Non-medical Prescribing is the essential self-test resource for nurses studying a prescribing qualification and preparing for exams.The book includes over 450 questions including full answers and explanations. The book includes: True or false questions Multiple choice questions Fill in the blanks questions Full glossary of terms Topics covered in this book include: Pharmacology Legal and ethical issues Therapeutic decision making Consultation skills Principles of safe prescribing Adverse drug reactions Drug licensing and handling Drug calculations Written by experienced non-medical prescribing lecturers, this test book will help you improve your results and tackle your exams with confidence!"I would like to congratulate the authors on an excellent revision aid. The resources identified, along with the questions designed to test students' knowledge, provides an eTable of ContentsAbout the AuthorsUsing this BookGuide to Useful Resources1. History of Prescribing - Independent and Supplementary2. Drug Development, Marketing and Administration3. Drug Licensing and Handling4. Getting to Know your BNF5. Legal and Ethical Issues in Prescribing6. Principles of Pharmacology7. Drug Calculations8. Consultation Skills and Clinical Decision Making9. Therapeutic Decision Making and Principles of Safe Prescribing10. Prescribing Errors11. Adverse Drug Reactions12. Cultural and Religious Issues13. ConcordanceGlossaryReferences

Read more less

Book SynopsisAdverse reactions to medicines continue to present a considerable burden on healthcare, causing considerable morbidity and mortality. As well as knowing about the benefits of medicines, healthcare professionals need to understand the problem of adverse drug reactions and be aware of how they can be prevented and managed.Trade Review'this book should be kept on the shelf to be used for frequent reference by professionals in primary care...while detailed in places...it is extremely readable and contains enough breadth to make it suitable for those who are visiting the topic for the first time.' Journal of Advanced Nursing 57, 01-Oct-06 * Journal of Advanced Nursing *Table of ContentsIntroduction to adverse drug reactions and pharmacovigilance: Melinda Cuthbert;Side effects and patients: Sheila C Noble;Pharmacogenetics: Munir Pirmohamed, Victoria Rollinson;Pregnancy: Jane Bass, Matthew Caldwell, Sophie Lumley, Catherine Nelson-Piercy, Nanda Surabhi ;Drug-induced cutaneous reactions: David Clifford, Sylwia Michlewska, Joanna Skwarski;Gastrointestinal system: Benjamin Kelly Hannan, Lynne Michelle Merchant, Duncan James Wilson;Hepatic disorders: Robbie Cord;Renal disorders: Aileen Dunleavy;Endocrine disorders: Yvonne Clark; Elaine McIvor;Respiratory disorders: Fiona McTaggart, Jenny Scott;Musculoskeletal disorders: Christine Randall;Blood disorders: Kelly Baillie;Mental health disorders: Anne Lee;Cardiovascular effects: Aaron Linstead;Neurological disorders: Fiona Needleman;Sexual dysfunction and infertility: Sherry A Wright, Joo Thong;

Read more less

Book SynopsisPharmacy OSCEs is the only pharmacy-specific OSCE revision guide. This easy-to-use book covers the key competencies that will be tested during your Objective Structured Clinical Examinations whether you are still studying or in practice.Table of Contents1. Responding to symptoms and history-taking; 2. Systems-based client assessment; 3. Legal aspects of prescriptions, and record-keeping; 4. Data retrieval and interpretation; 5. Clinical prescription management problems; 6. General health advice; 7. Counselling (medication and devices); 8. Problems involving calculations.

Read more less

Book SynopsisUpdated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition, explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications. Key updates reflect advances in PK/PD as related to clinical decision-making and drug research and development. An emphasis on the clinical relevance of drugs makes the book especially applicable to pharmacy students preparing for a career in clinical practice. Hundreds of graphs and tables provide visual representations of key pharmacokinetic/pharmacodynamic principles and effects. More than 200 carefully written study questions, with answers and in-depth explanat

Read more less

Book SynopsisTable of ContentsSection 1: Pharmacology and Drug Use 1 Preface 2 Pharmacology, Drug Names, and Classification Systems Section 2: Fundamentals of Pharmacology 3 General Principles of Drug Action 4 Molecular Aspects of Drug Action 5 Pharmacokinetic and Other Factors Influencing Drug Action 6 Pharmacodynamics and the Measurement of Drug Action Section 3: Drug Development 7 Drug Discovery and the Development of Small Molecules 8 Drug Discovery and the Development of Biologicals 9 Drug Safety, Toxicology, and Pharmacovigilance 10 Regulation of Drug Use Section 4: Drug Actions on Body Systems 11 Outline of Transmission and Drug Action in the Nervous System 12 Drugs and Neurological Disorders 13 Drugs and Pain 14 Drugs and the Cardiovascular System 15 Drugs and Blood: Haematopoiesis and Haemostasis 16 Drugs and the Inflammatory and Immune Response 17 Drugs and the Endocrine and Metabolic Systems 18 Drugs and the Renal System 19 Drugs and the Pulmonary System 20 Drugs and the Musculoskeletal System 21 Drugs and the Gastrointestinal System 22 Drugs and the Kidney and Genitourinary System 23 Drugs and the Skin 24 Drugs and the Eye 25 Drugs and the Ear 26 Drugs Used in Anaesthesia 27 Drug Use in Disorders of Nutrition 28 Drug Use in Dentistry Section 5: Drugs to Treat Infectious Diseases and Neoplasms 29 Antiviral Drugs 30 Antibacterial Drugs 31 Antifungal Drugs 32 Drugs and Parasites: Anti-protozoal and Antihelminthic Drugs 33 Drugs and Cancer Section 6: Drugs in the Community 34 Prescribing and Personalising Drug Treatments 35 Venoms, Toxins, Poisons, and Herbs 36 Drug Dependence and Drug Abuse

Read more less

Book SynopsisMedicine itself is sick. We hardly understand any disease and therefore need to chronically treat symptoms but not the causes. Consequently, drugs and other therapies help only very few patients; yet we are pumping more and more money into our healthcare system without any added value.Thus, the internationally renowned physician researcher, Harald Schmidt, predicts the end of medicine as we know it. On a positive note, digitization will radically change healthcare and lead to one of the greatest socioeconomic revolutions of mankind. He is one of the pioneers of "systems medicine", a complete redefinition of what we actually call a "disease", how we organize medicine and how we use Big Data to heal rather than treat, to prevent rather than cure. In this book the author first proves the deep crisis of medicine, but describes how medicine will become more precise, more uniform, safer and, surprisingly, also more affordable. Making a diagnosis will be taken over by artificial intelligence. Current, mainly organ-based medical specialists, disciplines and hospital departments will disappear. Physicians will become patient coaches working in interdisciplinary teams with pharmacists, physiotherapists, nutritionists, etc. and relieved of their workload. Illnesses, including cancer, will be prevented or cured in a precise manner. We will become 100 years and older. Health care spending will shift from chronic treatment of diseases to prevention and health maintenance, thereby dramatically reducing overall costs. Health will become a common good. But Harald Schmidt also warns that those who are not open to digitization will not benefit from these advances and will be left behind. Anyone who wants to benefit from the revolution of medicine must have a digital twin. Is this futurism? No, each of us can have his or her personal genome sequenced, microbiome analyzed, keep an electronic health record. The future has begun.Schmidt convincingly explains the limitations in the current practice of medicine and the need for big data and a systems approach. Prof. Ferid Murad MD, PhD, Nobel Laureate in Medicine 1998, USA Network Medicine, a new discipline that offers a network-based understanding of the cell and disease, is unavoidable if we wish to translate the advances in genomics into cures. Professor Harald Schmidt, a prominent expert in this space, offers the first coherent treatment of the topic, explaining the potential of a network-based perspective of human disease. Prof. Albert-László Barabási, Northeastern University and Harvard Medical School, Boston, USAVisionary, provocative, and full of insights. Professor Schmidt gives a unique and authoritative perspective to the past, present and future of medical science and clinical practice. And all presented in such an inimitable style. Prof. Robert F.W. Moulds, MBBS PhD FRACP, Former Dean Royal Melbourne Hospital Clinical School, AustraliaTable of ContentsPart I: Crisis, what crisis...? 1. Too Late2. Don’t Rely on Your Prescription3. Chronic Disease?4. No Prevention5. Male Plus Low Income = Double Whammy6. False Incentives7. The End of Big Pharma8. Research Not for Patients9. Organ-Based Medicine10. Interjection 1: How Healthy Do You Want to Be? Part II: The Medicine of the Future 11. Re-Discover the Whole Patient 12. Research for patients 13. Know Your Genes 14. Outnumbered 15. Your Exposome 16. Big Data Medicine 17. Healed 18. Well-Tech 19. Interjection 2: Superhumans Part III: The Future has Begun... 20. Self-diagnosis 21. Self-therapy 22. Your Digital Twin

Read more less

Book Synopsis

Read more less

Book SynopsisIntroduction to Pharmaceutical Calculations is an essential study aid for pharmacy students. The book contains worked examples and sample questions and answers.Table of Contents1 Introduction; 2 Rational Numbers; 3 Systems of Units; 4 Concentrations; 5 Dilutions; 6 Formulations; 7 Calculation of Doses; 8 Doses in Children; 9 Density, Displacement Volumes and Displacement Values; 10 Calculations Involving Molecular Weights; 11 Parenteral Solutions and Isotonicity; 12 Accuracy of Measurement; 13 Calculations Involving Information Retrieval.

Read more less

Book SynopsisThe revised fourth edition of this comprehensive handbook continues to provide a reliable, compact guide to all aspects of dialysis, incorporating best practice guidelines and including the most to up-to-date information on new techniques and patient management options.Trade ReviewIt is a good book. . . ideal for healthcare professionals new to dialysis or those wanting to learn more. . . A quality and practical book which helps you to manage patients. * Dr Harry Brown, Glycosmedia.com *Table of Contents1. The new patient with renal failure ; 2. Haemodialysis ; 3. Nursing a patient on haemodialysis ; 4. Home and Frequent Haemodialysis ; 5. Peritoneal dialysis ; 6. Nursing issues in peritoneal dialysis ; 7. Renal replacement therapy in acute kidney injury ; 8. Nutrition on dialysis ; 9. Special situations ; 10. Complications of ESKD: anaemia ; 11. Complications of ESKD: bone mineral disorders ; 12. Complications of ESKD: cardiovascular disease ; 13. Complications of ESKD: infection ; 14. Symptoms related to ESKD ; 15. Other complications of ESKD ; 16. Death in dialysis patients ; 17. Transplantation for dialysis patients ; 18. Drug Dosing ; 19. Standards and guidelines

Read more less

Book Synopsis

Read more less

Book SynopsisAlkylation of Enolates and Other Carbon Nucleophiles.- Reactions of Carbon Nucleophiles with Carbonyl Compounds.- Functional Group Interconversion by Substitution, Including Protection and Deprotection.- Electrophilic Additions to Carbon-Carbon Multiple Bonds.- Reduction of Carbon-Carbon Multiple Bonds, Carbonyl Groups, and Other Functional Groups.- Concerted Cycloadditions, Unimolecular Rearrangements, and Thermal Eliminations.- Organometallic Compounds of Group I and II Metals.- Reactions Involving Transition Metals.- Carbon-Carbon Bond-Forming Reactions of Compounds of Boron, Silicon, and Tin.- Reactions Involving Carbocations, Carbenes, and Radicals as Reactive Intermediates.- Aromatic Substitution Reactions.- Oxidations.- Multistep Syntheses.Trade ReviewFrom the reviews of the fifth edition: "Advanced Organic Chemistry … the well-known textbook for graduate students – has now appeared in a 5th edition. … Carey & Sundberg will be interesting to all students who seek a detailed understanding of organic chemistry, and who wish to refresh and embellish their existing knowledge. On the strength of the scope and quality of the explanations, this pair of texts is recommended for use as the resource of first resort for specific research questions in one’s later career." (www.organische-chemie.ch, January, 2008)Table of ContentsAlkylation of Enolates and Other Carbon Nucleophiles.- Reactions of Carbon Nucleophiles with Carbonyl Compounds.- Functional Group Interconversion by Substitution, Including Protection and Deprotection.- Electrophilic Additions to Carbon-Carbon Multiple Bonds.- Reduction of Carbon-Carbon Multiple Bonds, Carbonyl Groups, and Other Functional Groups.- Concerted Cycloadditions, Unimolecular Rearrangements, and Thermal Eliminations.- Organometallic Compounds of Group I and II Metals.- Reactions Involving Transition Metals.- Carbon-Carbon Bond-Forming Reactions of Compounds of Boron, Silicon, and Tin.- Reactions Involving Carbocations, Carbenes, and Radicals as Reactive Intermediates.- Aromatic Substitution Reactions.- Oxidations.- Multistep Syntheses.

Read more less

Book SynopsisTable of ContentsChapter 1. Introduction Chapter 2. Clinical check pre-dispensing and final check on dispensed medication Chapter 3 Responding to symptoms and counselling Chapter 4 Medication Reconciliation Chapter 5. Inter- and intra- professional assessments Chapter 6. Prescribing Skills Chapter 7. Competency-based Assessments Chapter 8. Dealing with Symptoms in the Community Pharmacy

Read more less

Book SynopsisTable of ContentsSection 1 Introduction and Background 1. Development of the pharmaceutical industry 2. Nature of disease and purpose of therapy 3. Therapeutic modalities Section 2 Drug Discovery 4. Drug target identification 5. Selecting the modality and planning the project 6. High throughput screening 7. Medicinal Chemistry 8. Biopharmaceuticals and related molecules 9. Emerging modalities: nucleotide based therapy, cell based therapy, gene therapy / Novel and Advanced Process 10. Metabolism and Pharmacokinetical strategies. 11. Role of pharmacology to include pharmacology of newer modalities 12. In vitro in vivo translation 13. Vaccines Section 3 Drug Development 14. Drug development introduction 15. Drug safety 16. Pharmaceutical development 17. Clinical development 18. Clinical imaging 19. Intellectual property 20. Regulatory affairs 21. Marketing and Patient access to medicines Section 4 Facts and Figures 22. Facts and Figures; and the Future

Read more less

Book SynopsisThis volume summarizes current research on the influence of plant polyphenols on human health, promoting collaboration between chemists and biologists to improve our understanding of their biological significance, and expanding the possibilities for their use. Table of ContentsPreface. 1. Introduction. 2. Hydrolyzable Tannins. 3. Condensed Tannins and Related Compounds. 4. Biotechnology. 5. Antioxidant Properties and Heart Disease. 6. Conformation, Complexation, and Antimicrobial Properties. 7. Polyphenols and Cancer. 8. Polyphenols in Commerce. 9. Polyphenols and Ecology. 10. Concluding Remarks. 11. Indexes.

Read more less

Book SynopsisTrade Review"This new edition may be recommended highly for purchase by undergraduate and professional doctoral students in pharmacy, as well as beginning graduate students in programmes in the pharmaceutical sciences and related areas. It will also be of great interest for use in continuing education courses for pharmacists, dentists, nurses and physicians. In addition, those with a scientific interest in herbalism and traditional medicine and nutrition will find the content of value. Moreover, this book will serve as a reliable source of information on natural product drugs for the interested lay reader. The previous editions of Fundamentals of Pharmacognosy and Phytotherapy have proven to be very highly regarded by readers. This updated and partially reorganised volume should be welcomed especially by educators of future pharmacists and of other healthcare professionals." -Prof. A. Douglas Kinghorn Columbus, OH, USA "This fourth edition of a work that has gained significant prominence and respect as a leading textbook contains highly valuable and authoritative information for anyone who is a student of pharmacy and/or pharmacognosy. It is also a valuable reference for industry quality-control personnel, herbalists, natural product researchers and others in the health professionals who wish to learn about the growing popularity of MAPs and how natural botanical and fungal preparations can provide a growing range of safe and reliable health benefits for consumers worldwide." -Mark Blumenthal Austin, Texas, USATable of ContentsPART A Fundamentals of Pharmacognosy SECTION 1 Pharmacognosy and Phytotherapy 1 Importance of Plants in Modern Pharmacy and Medicine 2 Pharmacognosy and Its History: People, Plants and Natural Products SECTION 2 Medicinal Plant Sciences 3 General Principles of Botany: Morphology and Systematics 4 Plant Families Yielding Important Medicines 5 Ethnobotany and Ethnopharmacology SECTION 3 Natural Products: An Introduction 6 Natural Product Chemistry 7 Analytical Methods for Natural Products 8 Natural Product Isolation and Structure Elucidation 9 Natural Products With Anticancer and Chemopreventive Effects 10 Antimicrobial Natural Products SECTION 4 Herbal Medicinal Products 11 The Complex Pharmacology of Herbal Medicines 12 Production, Quality Control and Standardisation of Herbal Medicines 13 Toxicity of Herbal Constituents 14 Herbal Medicine Interactions 15 Regulation and Pharmacovigilance for Herbal Medicines 16 Plants in Traditional Medicine Systems 17 Complementary, Alternative and Integrative Plant Therapies PART B Important Plant Medicines 18 The Gastrointestinal and Biliary System 19 The Cardiovascular System 20 Weight-Loss Supplements 21 The Respiratory System 22 The Central Nervous System 23 The Musculoskeletal System 24 Female Hormonal and Reproductive Conditions 25 The Male Reproductive System 26 Supportive Therapies for Stress, Ageing, Cancer and Debility 27 Topical Phytotherapy: Skin, Hair, Eye, Ear, Nose and Throat ANNEX Naming Herbal Drugs: Pharmaceutical (Latinised), Common English and Accepted Botanical Names (Binomials) and Synonyms Index

Read more less

Book SynopsisTrade ReviewFrom customer reviews of the previous edition: 'A great book. Everything is well organised and easy to understand. Covers all topics an undergraduate pharmacy student would need . useful for a practising pharmacist too.' 'This is an excellent introduction to pharmacy practice. It is an excellent read. Very well worth buying if you are a pharmacist or chemist.' 'I'm a final year medical student and found this great for all those learning outcomes that are really difficult to find. Things like details on the yellow card scheme and MHRA that I'd previously spent hours searching for - a concise, clear explanation of can be found here. There are also useful things like consent, capacity, health-behaviour models, prescription writing, controlled drugs and homeopathy information . mops up the learning outcomes that most other books don't cover. I've used it most for the practise drugs calculations as we have formatives on these and end of year OSCEs too!'Table of ContentsSection 1: The Patient Socio-behavioural aspects of health and illness Socio-behavioural aspects of treatment with medicines Communication skills for pharmacists and their team Consent History Taking/ Gathering Information Concordance Advice giving and the pharmacist as a health trainer Section 2: The Medicine Control of medicines The prescribing process and evidence-based medicine Drug evaluation and pharmacoeconomics Formularies in pharmacy practice Complementary and alternative medicines Using calculations in pharmacy practice Veterinary pharmacy Section 3: The Medicine Formulation Dispensing techniques (compounding and good practice) Oral unit dosage forms Packaging Solutions Suspensions Emulsions External preparations Suppositories and pessaries Powders and granules Section 4: The Specialized Pharmacy Product Production of sterile products Parenteral products Opthalmic products Inhaled products Parenteral nutrition and dialysis Radiopharmacy Specialized services Appliances Section 5: The Pharmacy Safety Process Clinical governance Risk management Standard operating procedures Audit Information retrieval in pharmacy practice Control of health professionals and their staff Continuing professional development and revalidation Section 6: The role of pharmacy in healthcare The role of pharmacy in healthcare Ethics - the theory Ethics in practice and ethical dilemmas Public health Structure and organization of pharmacy Intra- and inter-professional working Section 7: The patient, their medicine and beyond The prescription Patient charges of medicines and their impact on access Routes of administration and dosage forms Labelling of dispensed medicines Monitoring the patient The role of the pharmacist in medicines optimisation Public health and pharmacy interventions Substance use and misuse

Read more less

Book SynopsisTrade ReviewFrom customer reviews of the previous edition: 'Brilliant Book. I passed the PSA at 96% and was in the top 0.5% of the country.' 'Buy this book for the PSA, fantastic book, straight to the point.' 'Must-have book for the PSA, can enter the exam with so much more confidence knowing roughly what format/common things to know.' 'Excellent - really well-written book. short and sweet. Has all the important drugs, SE, interactions etc. prepares you well for the PSA (and other prescribing exams)' 'Brilliant book'Table of Contents1 Basic principles of prescribing 2 Prescription review: A foolproof plan 3 Data interpretation 4 Planning management 5 Communicating information 6 Calculation skills 7 Prescribing: Doing it yourself 8 Drug monitoring 9 Adverse drug reactions 10 Mock examinations

Read more less

Book SynopsisTable of ContentsPreface ....................................................................... vii Contributors ............................................................. ix Acknowledgements .................................................. xiii What is 'pharmaceutics'?......................................... xv Kevin M.G. Taylor and Michael E. Aulton 1. Design of dosage forms.................................. 1 Peter York 2. Dissolution and solubility ............................. 13 Michael E. Aulton 3. Properties of solutions ................................... 30 Michael E. Aulton 4. Surfaces and interfaces ................................... 39 Graham Buckton 5. Disperse systems.............................................. 50 David Attwood 6. Rheology........................................................... 81 Christopher Marriott 7. Kinetics ............................................................. 101 Gareth R. Williams and John P. Malkinson 8. Solid-state properties .................................... 114 Graham Buckton 9. Particle size analysis ..................................... 126 Kevin M.G. Taylor 10. Particle size reduction and size separation....................................................... 143 Michael E. Aulton 11. Mixing............................................................. 156 Andrew M. Twitchell 12. Powder flow................................................... 172 Michael E. Aulton 13. Fundamentals of microbiology................... 184 Lara-Marie Barnes and Geoffrey W. Hanlon 14. Pharmaceutical applications of microbiological techniques.......................... 208 Lara-Marie Barnes and Norman A. Hodges 15. Action of physical and chemical agents on microorganisms....................................... 229 Lara-Marie Barnes, Geoffrey W. Hanlon and Norman A. Hodges 16. Principles of sterilization ............................. 247 Susannah E. Walsh, Katie Laird and Jean-Yves Maillard 17. Sterilization in practice ................................ 257 Jean-Yves Maillard, Katie Laird and Susannah E. Walsh 18. Introduction to biopharmaceutics.............. 275 Marianne Ashford and Kevin M.G. Taylor 19. Gastrointestinal tract e physiology and drug absorption............................................. 279 Marianne Ashford and Kevin M.G. Taylor 20. Bioavailability e physicochemical, dosage form and formulation factors ........ 297 Marianne Ashford, Kevin M.G. Taylor and Hala M. Fadda 21. Assessment of biopharmaceutical properties ....................................................... 320 Marianne Ashford and Kevin M.G. Taylor 22. Dosage regimens ........................................... 343 Soraya Dhillon and Nkiruka Umaru 23. Pharmaceutical preformulation .................. 360 Simon Gaisford 24. Solutions ........................................................ 386 Sudaxshina Murdan 25. Clarification ................................................... 397 Andrew M. Twitchell 26. Suspensions ................................................... 407 Susan A. Barker 27. Emulsions and creams ................................. 424 Gillian M. Eccleston 28. Ointments, pastes, gels, cutaneous patches and topical sprays........................... 453 Majella E. Lane 29. Powders, granules and granulation ............ 463 Michael E. Aulton 30. Drying............................................................. 483 Michael E. Aulton and Satyanarayana Somavarapu 31. Tablets and compaction............................... 501 Göran Alderborn and Göran Frenning 32. Modified-release oral drug delivery ............ 542 Emma L. McConnell, Christine M. Madla and Abdul W. Basit 33. Coating of tablets and multiparticulates ... 558 Stuart C. Porter 34. Continuous manufacturing of tablets ........ 574 Aktham Aburub and Hala M. Fadda 35. Hard capsules ................................................ 586 Brian E. Jones 36. Soft capsules .................................................. 599 Stephen Tindal 37. Dissolution testing of solid dosage forms............................................................... 612 Ana Cristina Freire, Francesca K.H. Gavins and Abdul W. Basit 38. Parenteral drug delivery ............................... 626 Robert Lowe 39. Pulmonary drug delivery ............................. 641 Kevin M.G. Taylor 40. Nasal drug delivery....................................... 658 Gary P. Martin and Alison B. Lansley 41. Ocular drug delivery..................................... 677 Hala Fadda, Ashkan Khalili, Peng Tee Khaw and Steve Brocchini 42. Otic drug delivery ......................................... 701 Xu Liu, Hugh Smyth and Feng Zhang 43. Topical and transdermal drug delivery ...... 713 Adrian C. Williams 44. Rectal and vaginal drug delivery................. 735 Kalliopi Dodou 45. Preparation and delivery of biopharmaceuticals....................................... 752 Ijeoma F. Uchegbu and Andreas G. Schätzlein 46. Pharmaceutical nanotechnology and nanomedicines .............................................. 768 Yvonne Perrie 47. Radiopharmaceuticals................................... 789 Neil Hartman and Margaret Cooper 48. The formulation and manufacture of plant medicines............................................. 805 G. Brian Lockwood 49. Design and administration of medicines for paediatric and geriatric patients............ 818 Catherine Tuleu, Mine Orlu and David Wright 50. Packaging ....................................................... 833 Sudaxshina Murdan 51. Chemical stability in dosage forms............ 848 Andrew R. Barnes and Mark Santillo 52. Microbial contamination, spoilage and preservation of medicines............................ 860 Norman A. Hodges and Lara-Marie Barnes 53. Product stability and stability testing......... 871 Paul Marshall 54. Pharmaceutical quality: the application of pharmaceutics in medicines regulation ....................................................... 894 Kevin M.G. Taylor, Majella E. Lane and Khalid A. Sheikh Self-assessment questions Sudaxshina Murdan Please check your eBook at https://studentconsult. inkling.com/ for self-assessment questions. See inside cover for registration details. Index.......................................................................... 915

Read more less

Book SynopsisMaking Medicines is a concise, chronological discussion of the history of therapeutics and pharmacy from the Egyptians through to the present day. It focuses on the discovery and uses of medicines to treat illness through the ages, and the evolving role of the pharmacist.Trade Review'From the Egyptians to present-day, the reader will find a chronological discussion about the discovery and uses of medicines to treat illness. There are two sections that illustrate how pharmacy has developed and evolved over the years. Edited by Stuart Anderson, this book will appeal to a large audience and deliver unique content to you, the reader.'International Journal of Pharmaceutical Compounding, Volume 4. Issue 51. December 28, 2007 * International Journal of Pharmaceutical Compounding *'...an interesting read for the public, students, and those who want to find out more about the history of pharmacy. Although the title of the text suggested it was a "brief" history, it was clear to me that an extensive amount of information was compiled through many different resources.'Megan Thompson, Pharm.D. College of Pharmacy, University of New Mexico, Drug Development and Industrial Pharmacy, 32:909, 2006 -- Megan Thompson * Drug Development and Industrial Pharmacy *'Making Medicines merits a place in any library that shelves a historical collection about the field of health...'Pharmacy in History 48 (3), 148-149 * Pharmacy in History *Table of ContentsPart 1: The Development of Pharmacy: 1. Pharmacy in the Ancient World Up to 1231 AD: William Court; 2. Pharmacy in the Mediaeval World 1231 to 1617 AD: Juanita Burnby; 3. Pharmacy in the Early Modern World 1671 to 1841 AD: Peter M Worling; 4. Pharmacy in the Modern World 1841 to 1986 AD: John A Hunt; Part 2: The Practice of Pharmacy: 5. Pharmacy Education: Melvin Earles; 6. Retail Pharmacy Practice in UK: Peter G Homan; 7. Pharmacy Practice in Hospitals: Shirley Ellis; 8. The Growth of the Pharmaceutical Industry: Judy Slinn; Part 3: The Products of Pharmacy: 9. A History of Therapeutic Discovery: Walter Sneader, Viviane Quirke; 10. A History of Dosage Form: William A Jackson; 11. A History of Drug Safety: 12. From Secret Remedies to Prescription Medicines: Part 4: Pharmacy Today and Tomorrow: 13. Pharmacy Today: Nicholas Wood; 14. Pharmacy Tomorrow: David Taylor

Read more less

Book SynopsisWritten by a group of multi-professional authors, this fully updated third edition builds on the success of this classic text. The book explores a number of key areas for prescribers, including prescribing within a multidisciplinary team context, consultation skills, ethical and legal issues surrounding prescribing, the psychology and sociology of prescribing, and applied pharmacology. Among the other topics featured are monitoring skills, medicines concordance, evidence based prescribing, prescribing within a public health perspective, calculation skills, prescribing in dermatology, and minimizing the risk of prescribing errors. Each chapter has been revised and additional chapters on antimicrobial prescribing, education and training to become a prescriber, and a new section on renal impairment have been added. This book is an essential resource for both new and experienced prescribers and anyone undertaking the non-medical prescribing (NMP) programme including nurses, pharmacists, alTrade Review'I am delighted that the third edition of Independent and Supplementary Prescribing: An Essential Guide is now published. It all began with Neighbourhood Nursing report which I chaired in 1986, which was hugely valuable for community nurses, GPs, but above all the patients. With the strong support of The Royal College of Nursing, and others like Matt Griffiths and Molly Courtenay, it became embedded as an idea and a practice. Like all good ideas it grew, and other professions can now prescribe but healthcare changes fast and we must keep up-to-date. So, I warmly welcome this third edition building on the popularity of the first two. This book is essential reading for non-medical practitioners undertaking the prescribing course along with medical students learning to prescribe. With such valuable advice and educational materials the future is bright for better care for patients and skilled practitioners.' Baroness Julia Cumberlege, CBE, DL'This book offers good discussion on pertinent topics for prescribers, including good communication skills, ethical and legal issues, influences on prescribing habits, adverse drug reactions, drug interactions, research studies and statistical interpretation, and some useful information on disease states and prescribing for them.' Judith Klevan, Doody's ReviewsTable of Contents1. Non-medical prescribing: An overview Molly Courtenay and Matt Griffiths; 2. Non-medical prescribing in a multidisciplinary team context Barbara Stuttle, Sam Sherrington and Dianne Hogg; 3. Consultation skills and decision making Gary Morris and Anne Baird; 4. Legal aspects of independent and supplementary prescribing Mark Gagan; 5. Ethical issues in independent and supplementary prescribing Jo Taylor and John Adams; 6. Psychology and sociology of prescribing Angel Chater and Hannah Family; 7. Applied pharmacology Kat Hall and Michele Cossey; 8. Monitoring skills (asthma, diabetes, renal impairment) Sharon Sturney, Sian Bodman and Sally Haslam; 9. Promoting concordance in prescribing interactions Sue Latter; 10. Evidenced-based prescribing Gerry Morrow; 11. Independent/supplementary prescribing: A public health perspective Sarah O'Brien; 12. Calculation skills Alison Eggleton; 13. Prescribing in practice: How it works Polly Buchanan; 14. Minimising the risk of prescribing error Cate Whittlesea; 15. Prescribing for undergraduate students Rosemary Lim and Molly Courtenay; 16. Antimicrobial prescribing Enrique Castro-Sanchez.

Read more less

Book SynopsisAre you considering studying pharmacology or pharmacy at university? Do you want to know more about the course? Or where it could take you? From employment prospects and places to work to finding funding and writing the personal statement, this fully revised and updated edition of Getting into Pharmacy and Pharmacology provides you with all the information and guidance to submit your application and start a career in one of the UK’s growing industries. Learn what it takes from experienced admissions tutors from top universities to have your application at the top of the pile. Getting into Pharmacy and Pharmacology Courses includes: - A typical day in the life of a pharmacy and pharmacology student - Examples of courses and teaching methods - The requirements of entry for different pharmacy and pharmacology courses - Future career paths and industries to work in Founded in 1973, MPW, a group of independent sixth-form colleges, has one of the highest number of university placements each year of any independent school in the UK and has developed considerable expertise in the field of applications strategy. They author the Getting Into Guides which explain the application process for many popular university subjects.Table of ContentsAbout the author Acknowledgements Introduction Chapter 1 What are pharmacy and pharmacology? Chapter 2 Studying pharmacy and pharmacology Chapter 3 Choosing your course Chapter 4 Work experience Chapter 5 The UCAS application process Chapter 6 Personal statement Chapter 7 Interviews Chapter 8 Non-standard applications Chapter 9 Results day Chapter 10 Fees and funding Chapter 11 Careers in pharmacy and pharmacology Further information Glossary

Read more less

Book SynopsisEssential Prescribing provides medical students with an easy-to-follow overview of the drugs they are most likely to encounter at medical school and as they start their medical careers. The book benefits from the same landscape format and approach as Scion’s bestselling Essential Examination. Each class of drug is detailed using a common tabular format, based on the following sections: Examples Mode of Action Routes of Delivery Indications, Cautions and Contraindications Interactions Monitoring Side-effects Patient counselling This consistent approach helps the reader quickly find the pertinent information for the common drugs and situations they are likely to come across, so they can become confident of prescribing the correct drugs for the patient in appropriate doses. The book also features a questions and answer section at the end of the book for the reader to assess their knowledge. All medical students and foundation doctors now have to prove their prescribing competence by taking the Prescribing Safety Assessment (PSA). Essential Prescribing not only arms the reader with the key knowledge for the PSA, but also provides them with the core prescribing knowledge they will need as their medical careers progress. The book is also ideal for Independent Prescriber V300 courses.Trade ReviewGreat book with all the common drugs 'I love this book. It’s set up just like Essential Examination (Ruthven) and includes all the common drugs a newly qualified doctor is expected to know, including knowledge to face the PSA. It has lots of mnemonics for every drug which I am personally not a big fan of but that’s only because I don’t learn from mnemonics generally. Really liked the sections on emergency drugs and fluid presc ribing.' Amazon reviewer Easy, concise, systematic guidelines for prescribing essentials of patient care! 'This book is a wealth of information! Well written in a simple concise, easy to follow guidelines for prescribing medications, oxygen, intravenous fluids ...extra and is divided by the system involved and has a section specifically for patient counseling which makes this book unique.' Amazon reviewer Useful 'A straight forward and useful book which gives you the essential info about many common drugs.' Amazon reviewer Good book 'A well written book...good for medical revision!!' Amazon reviewer Table of ContentsPreface; Acknowledgments; Abbreviations General prescribing rules Section I: Prescribing by system 1. Cardiovascular system 2. Haematological system 3. Respiratory system 4. Gastrointestinal system 5. Renal system 6. Endocrine system 7. Female reproductive system 8. Male reproductive system 9. Central nervous system 10. Musculoskeletal system Section II: Prescribing by situation 11. Intravenous fluids 12. Oxygen therapy 13. Antibiotics 14. Analgesia 15. Emergency drugs 16. Prescribing in the elderly Section III: Self-assessment questions and answers 17. PSA-style questions and answers 18. Test your knowledge questions and answers Appendix: Mnemonic acknowledgments Index

Read more less

Book Synopsis The most trusted source on the subject available today, Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 12th Edition equips pharmacy students with everything they need to master the intricacies of pharmaceutical dosage form design and production and achieve successful outcomes in their courses and beyond. Reflecting the latest CAPE, APhA, and NAPLEX® competencies, this trusted, extensively updated resource clarifies the interrelationships between pharmaceutical and biopharmaceutical principles, product design, formulation, manufacture, compounding, and the clinical application of the various dosage forms in patient care, as well as regulations and standards governing the manufacturing and compounding of pharmaceuticals. New and revised content throughout keeps students up to date with current approaches to key coverage areas, and additional case studies demonstrate concepts in action to reinforce understanding and prepare students for the clinical challenges ahead. NEW! Patient counseling content in each chapter helps students confidently address this increasing role for pharmacists. UPDATED! Content familiarizes students with the latest practices and approaches to pharmaceutical dosage form design and production, including emerging topics such as biologics. UPDATED! Additional clinical case studies demonstrate pharmaceutical concepts in a real-world context and ready students for practice. UPDATED! Chapter review questions test students’ retention and understanding of key content. Clinical emphasis ensures the scientific understanding and practical application for success in practice.

Read more less

Book SynopsisMedicine itself is sick. We hardly understand any disease and therefore need to chronically treat symptoms but not the causes. Consequently, drugs and other therapies help only very few patients; yet we are pumping more and more money into our healthcare system without any added value.Thus, the internationally renowned physician researcher, Harald Schmidt, predicts the end of medicine as we know it. On a positive note, digitization will radically change healthcare and lead to one of the greatest socioeconomic revolutions of mankind. He is one of the pioneers of "systems medicine", a complete redefinition of what we actually call a "disease", how we organize medicine and how we use Big Data to heal rather than treat, to prevent rather than cure. In this book the author first proves the deep crisis of medicine, but describes how medicine will become more precise, more uniform, safer and, surprisingly, also more affordable. Making a diagnosis will be taken over by artificial intelligence. Current, mainly organ-based medical specialists, disciplines and hospital departments will disappear. Physicians will become patient coaches working in interdisciplinary teams with pharmacists, physiotherapists, nutritionists, etc. and relieved of their workload. Illnesses, including cancer, will be prevented or cured in a precise manner. We will become 100 years and older. Health care spending will shift from chronic treatment of diseases to prevention and health maintenance, thereby dramatically reducing overall costs. Health will become a common good. But Harald Schmidt also warns that those who are not open to digitization will not benefit from these advances and will be left behind. Anyone who wants to benefit from the revolution of medicine must have a digital twin. Is this futurism? No, each of us can have his or her personal genome sequenced, microbiome analyzed, keep an electronic health record. The future has begun.Schmidt convincingly explains the limitations in the current practice of medicine and the need for big data and a systems approach. Prof. Ferid Murad MD, PhD, Nobel Laureate in Medicine 1998, USA Network Medicine, a new discipline that offers a network-based understanding of the cell and disease, is unavoidable if we wish to translate the advances in genomics into cures. Professor Harald Schmidt, a prominent expert in this space, offers the first coherent treatment of the topic, explaining the potential of a network-based perspective of human disease. Prof. Albert-László Barabási, Northeastern University and Harvard Medical School, Boston, USAVisionary, provocative, and full of insights. Professor Schmidt gives a unique and authoritative perspective to the past, present and future of medical science and clinical practice. And all presented in such an inimitable style. Prof. Robert F.W. Moulds, MBBS PhD FRACP, Former Dean Royal Melbourne Hospital Clinical School, AustraliaTable of ContentsPart I: Crisis, what crisis...? 1. Too Late2. Don’t Rely on Your Prescription3. Chronic Disease?4. No Prevention5. Male Plus Low Income = Double Whammy6. False Incentives7. The End of Big Pharma8. Research Not for Patients9. Organ-Based Medicine10. Interjection 1: How Healthy Do You Want to Be? Part II: The Medicine of the Future 11. Re-Discover the Whole Patient 12. Research for patients 13. Know Your Genes 14. Outnumbered 15. Your Exposome 16. Big Data Medicine 17. Healed 18. Well-Tech 19. Interjection 2: Superhumans Part III: The Future has Begun... 20. Self-diagnosis 21. Self-therapy 22. Your Digital Twin

Read more less

Book SynopsisBillions of people worldwide take medicines every day to treat important diseases. In many cases, however, neither the doctor nor the pharmacist has the time to explain to the patient why a particular drug should be taken, how the drug works and what side effects to expect. Of course, the patient can find "everything" about a particular drug on the Internet. But how reliable and understandable is this information? In addition, most Internet sources do not point out the interrelationships between different diseases and drug interactions. Written by an experienced and well-known textbook author, this book provides an overview of the most common diseases and the drugs used to treat them. The book is designed for a general audience. It provides patients with essential information about how medications work and what side effects and interactions to expect. Finally, the book gives patients advice on what they can do themselves to improve drug therapy and safety. Summaries, bullet points, tables and diagrams support the information process.Table of ContentsChapter 1. What Should I Know About Drugs?.- Chapter 2. Painkillers (analgesics).- Chapter 3. Drugs for Gastrointestinal Disorders.- Chapter 4. Drugs for Respiratory Diseases.- Chapter 5. Drugs for Cardiovascular Diseases.- Chapter 6. Drugs for Metabolic Disorders.- Chapter 7. Drugs for Her and Him.- Chapter 8. Drugs for Neurological Disorders.- Chapter 9. Drugs for Mental Disorders.- Chapter 10. Drugs for Eye Diseases.- Chapter 11. Drugs for Cancer and Autoimmune and Infectious Diseases.

Read more less

Book SynopsisWhile palliative care has adopted a holistic approach to treatment, medication driven symptom management ostensibly forms the critical aspect of care. Prescribing in palliative care can be extremely complex because the patient may often have comorbidity, or occasionally multimorbidity. The associated polypharmacy further complicates the pharmacological management of symptoms being caused by the palliative condition. This can be daunting for healthcare professionals and can negatively impact upon the effectiveness of care provided.Fully revised and updated, the third edition of Drugs in Palliative Care provides an accessible and succinct overview of the main drugs that are encountered in palliative care clinical practice. The text begins by providing a clinical pharmacology overview and prescribing guidance, then contains over 160 monographs of palliative care drugs, in an easy to access A-Z format.Trade ReviewReview from previous edition I like the handy pocket-size and the drug monographs are organised in an easy-to-use A-Z format. This book would be very useful as a quick reference on any palliative care unit. * IAHPC Newsletter *Table of ContentsDetailed contents Symbols and abbreviations 1: Clinical pharmacology overview 2: Prescribing guidance 3: Drug Monograph A-Z Index

Read more less

Book SynopsisThis established textbook covers every aspect of drug properties from the design of dosage forms to their delivery by all routes to sites of action in the body.Trade Review"The text is highly illustrated throughout and includes key points and appropriate examples, providing clinicians with some easily accessible and relevant information. Some examples of adverse events due to excipients, impurities, the influence of dosage forms, materials in delivery devices and even light-induced effects are also included. Although the detection of adverse events is not an easy task, these examples may assist clinicians in asking the right questions to predict or identify adverse effects. The new focus on applications to clinical practice in this edition has extended its usefulness from pharmacy and pharmaceutical scientist courses to clinicians seeking an understanding of formulations, especially for children and older people, and in identifying the cause of adverse events."Beverley Glass, Australian Prescriber October 2016 -- Beverley Glass * Australian Prescriber *

Read more less

Book Synopsis

Read more less

Book Synopsis

Read more less

Book SynopsisDrug Design and Development outlines the processes involved in the design and development of new drugs and emphasises the significance of these processes to the practice of pharmacy. The book highlights why it is important that all practicing pharmacists, including those working in hospitals or high street stores, have a solid understanding of the process of the design and development of the drugs they interact with. It adopts an integrated approach, formulated to complement courses which are designed in line with the General Pharmaceutical Council''s new curriculum requirements. Furthermore, this is the only integrated textbook to consider both drug design and development within one volume. Throughout the book, the journey of the drug, from discovery to market, is presented in an integrated fashion, emphasising the interconnection of all the processes involved.Trade ReviewWell written text that guides students through the complex elements of the drug development process. It has a chemistry focus and utilises 'key points' to reinforce the important aspects at regular opportunities. * Dr James F. Brown, University of Portsmouth *Table of Contents1: Introduction Part 1 Drug targets 2: Receptors and signal transduction 3: Enzymes as drug targets 4: Nucleic acids and protein synthesis as drug targets 5: Other drug targets Part 2 Origins of drug molecules 6: Sources of lead compounds 7: Drug synthesis 8: Optimisation of lead compounds 9: Computer-aided drug design 10: Combinatorial chemistry and high-throughput screening 11: Biotechnology and biopharmaceuticals Part 3 Biological aspects of drug development 12: Drug metabolism 13: Pharmacogenetics and pharmacogenomics 14: Toxicity testing Part 4 Preformulation studies 15: Solubility and drug development 16: Solid state characteristics 17: Drug stability Part 5 Clinical research 18: Clinical research and its regulation 19: Design and management of clinical trials

Read more less

Book SynopsisSomatic Gene Therapy, Paradigm Shift or Pandora's Box: A Perspective on Gene Therapy.- Gene Therapy for Cancer: Deceiving the Malignant Cell.- Gene Self-Assembly (GENSA): Facilitating the Construction of Genes and Vectors.- Gene Expression.- Tumour Genotype and Response to Cytotoxic Gene Therapy.- Protein Binding Matrices: Tools for Phenol-free Cloning and Vector Assembling.- Gene Transfer into Eukaryotic Cells.- Plasmid DNA Manufacturing.- Quality Assurance and Quality Control for Viral Therapeutics.- Analytical Assays to Characterise Adenoviral Vectors and Their Applications.- Validation of Gene Therapy Manufacturing Processes: A Case Study for Adenovirus Vectors.- Gene Delivery.- Regulatory Issues in Gene Therapy. Good Science - Good Sense.- Regulatory Aspects in Gene Therapy: Special Highlights on European Regulation.- Regulatory Issues for Process Development and Manufacture of Plasmids Under Contract.- Risk Assessment in Gene Therapy.Table of ContentsSomatic Gene Therapy, Paradigm Shift or Pandora's Box: A Perspective on Gene Therapy; M. Lawler. Gene Therapy for Cancer: Deceiving the Malignant Cell; M. Lawler. Gene Self-Assembly (GENSA): Facilitating the Construction of Genes and Vectors; C.P. Hodgson. Gene Expression; J. Kaur, et al. Tumour Genotype and Response to Cytotoxic Gene Therapy; P.T. Daniel, et al. Protein Binding Matrices: Tools for Phenol-free Cloning and Vector Assembling; V.I. Evtushenko. Gene Transfer into Eukaryotic Cells; M. Weber. Plasmid DNA Manufacturing; M. Schleef, et al. Quality Assurance and Quality Control for Viral Therapeutics; S.S. Kuwahara. Analytical Assays to Characterise Adenoviral Vectors and Their Applications; E. Lehmberg, et al. Validation of Gene Therapy Manufacturing Processes: A Case Study for Adenovirus Vectors; D. Vacante, et al. Gene Delivery; A. Anand. Regulatory Issues in Gene Therapy. Good Science - Good Sense; N. Chew, J.A. Cavagnaro. Regulatory Aspects in Gene Therapy: Special Highlights on European Regulation; O. Cohen-Haguenhauer. Regulatory Issues for Process Development and Manufacture of Plasmids Under Contract; J.M. Jenco. Risk Assessment in Gene Therapy; A. Anand, S.K. Arora. Index.

Read more less

a huge range and FREE tracked UK delivery on ALL orders.

Read more less

Book SynopsisThis fifth issue in the Industry and Health Care series takes a quick turn through unpredictable and only partially charted waters.Table of Contents1. What Can Industry Do for HMOs and HMOs for Industry?.- HMOs and Health Care Costs.- Industry and HMOs.- Notes.- 2. Defining Corporate Strategies and Goals.- Organizational Patterns and Beginning Steps.- Savings Potential in an HMO: The First Cut and a Second Look.- Data Deficiencies: Approximations and Proxies.- The Current Benefit Package and Management—Labor Relations.- The Physician—Patient Relationship and the Tightrope of Medical Politics.- Geography: Concentration and Clout.- The “Bottom Line” Is the Bottom Line….- …Or Is It?.- Notes.- 3. Identifying Available Options.- Salaried Group HMOs: Roots in Prepaid Group Practices.- Fee-for-Service HMOs.- Other Emerging HMO Models.- Potential Partners for HMO Development.- Notes.- 4. Assessing Legal Obstacles.- Liability Issues for the HMO.- Corporate Liability.- State Law.- ERISA.- Antitrust Law.- Conclusion.- Notes.- 5. Issues for the Future.- The Issues for Industry: Setting Realistic Expectations and Goals.- The Issues for HMOs: Amassing Useful Data and Establishing Credible Records.- The Broader Policy Issue: Who Ought to Realize the Savings?.- Notes.- Appendix I A National Call to Action: Secretary Califano’s HMO Conference.- Appendix II Bay State Health Care Foundation Hearings.- Appendix III Panel Discussion: Should Industry Sponsor Fee-for-Service HMOs?.

Read more less

Book Synopsis

Read more less

Book SynopsisTable of ContentsPreface vi Contributors vii Part 1 Principles of clinical pharmacology 1 Pharmacodynamics and pharmacokinetics 3 2 Clinical trials and drug development 29 3 Pharmacoeconomics: the economic evaluation of new drugs 35 4 Practical prescribing 42 Part 2 Aspects of prescribing 5 Gastrointestinal system 51 6 Cardiovascular system: Management of coronary artery disease and its complications 63 7 Respiratory system 102 8 Nervous system 113 9 Infection 142 10 Drugs and endocrine disease 175 11 Genitourinary system 196 12 Malignant disease 211 13 Drugs and the blood 221 14 Musculoskeletal system 236 15 Immunopharmacology 242 16 Travel medicine 255 17 Analgesia and anaesthesia 266 18 Poisoning and drug overdose 281 Index 295

Read more less

Book SynopsisFrom "pharma bros" to everday household budgets, just how did the pharmaceutical industry betray its own history—and how can it return to its tradition of care?It’s an unfortunate and life-threatening fact: one in five Americans has skipped vital prescriptions simply because of the cost. These choices are being made even though we have reached a point in the conveyance of medical options where cancers can be cured and sight restored for those blinded by rare genetic disorders. How, in this time of such advancements, did we reach a point, where people cannot afford the very things that could save their lives? As the COVID-19 global pandemic has pointed out, we need the leadership of scientists, researchers, public health officials and lawmakers alike to guide us through not only in times of a global health crisis, but also during far more mundane times. For the first time in decades, people from all walks of life face the same need for medicine. It is time to discuss the tough questions about drug pricing in an open, honest and, hopefully, transparent manner. But first we must understand how we, as a society, got here. Medicines are arguably the most highly regulated—and cost-inflated—products in the United States. The discovery, development, manufacturing and distribution of medicines is carried out by an ever more complex and crowded set of industries, each playing a part in a larger “pharmaceutical enterprise” seeking to maximize profits. But this was not always the case. The Price of Health is the reveals the story of how the pharmaceutical enterprise took shape and led to the present crisis. The reputation of the pharmaceutical industry is suffering from self-inflicted wounds and its continued viability, indeed survival, is increasingly questioned. Yet the drug makers do not shoulder all the blame or responsibility for the current price crisis. Deeply researched, The Price of Health gives us hope as to how we can still right the ship, even amidst the roiling storm of a global pandemic. How have medicines have been made and distributed to consumers throughout the years? What sea of changes that have contributed to rising costs? Some individuals, actions, and systems will be familiar, others may surprise. Yet the combined implications of these actions for will be surprising and at times shocking to both industry professionals and average Americans alike. Like so much else in human history, the history of the pharmaceutical enterprise is populated mostly by well-intended and even noble individuals and organizations. Each contributed to the formation or maintenance of structures meant to improve the quality and quantity of life through the development and distribution of medicines. And yet systems originally created to do good have often been subverted in ways contrary to the motivations of their creators. Only by understanding this disconnect can we better tackle the underlying problems of the industry head on, preventing foreseeable, and thus avoidable, medical calamities to come.

Read more less

Book SynopsisConsistently revised and updated for more than 60 years to reflect the most current research and practice, Martin’s Physical Pharmacy and Pharmaceutical Sciences, 8th Edition, is the original and most comprehensive text available on the physical, chemical, and biological principles that underlie pharmacology and the pharmaceutical sciences. An ideal resource for PharmD and pharmacy students worldwide, teachers, researchers, or industrial pharmaceutical scientists, this 8th Edition has been thoroughly revised, enhanced, and reorganized to provide readers with a clear, consistent learning experience that puts essential principles and concepts in a practical, approachable context. Updated content reflects the latest developments and perspectives across the full spectrum of physical pharmacy and a new full-color design makes it easier than ever to discover, distinguish, and understand information—providing users the most robust support available for applying the elements of biology, physics, and chemistry in work or study. NEW! Enhanced organization clarifies the clinical relevance of content throughout the text and makes learning more efficient for PharmD students. NEW! Full-color design emphasizes essential information and delivers an engaging learning experience. Revised content throughout, including areas such as Molecular Dispersions, Pharmaceutical Micromeritics, Formulation Engineering, Pharmaceutical Biotechnology, and more, provide further clarification and understanding. Abundant examples reinforce how physical chemical and biopharmaceutical principles apply to practice. Key Concept boxes keep students focused on the most important chapter content.

Read more less

Table of Contents1 Duncan, H. Ringsdorf, R. Satchi-Fainaro: Polymer Therapeutics: Polymers as Drugs, Drug and Protein Conjugates and Gene Delivery Systems: Past, Present and Future Opportunities.- 2 P.K. Dhal, S.R. Holmes-Farley, C.C. Huval, T.H. Jozefiak: Polymers as Drugs.- 3 R.J. Amir, D. Shabat: Domino Dendrimers.- 4 G. Pasut, F.M. Veronese: PEGylation of Proteins as Tailored Chemistry for Optimized Bioconjugates.- E. Wagner, J. Kloeckner: Gene Delivery Using Polymer Therapeutics.-

Read more less

a huge range and FREE tracked UK delivery on ALL orders.

Read more less