Description
Book SynopsisSomatic Gene Therapy, Paradigm Shift or Pandora's Box: A Perspective on Gene Therapy.- Gene Therapy for Cancer: Deceiving the Malignant Cell.- Gene Self-Assembly (GENSA): Facilitating the Construction of Genes and Vectors.- Gene Expression.- Tumour Genotype and Response to Cytotoxic Gene Therapy.- Protein Binding Matrices: Tools for Phenol-free Cloning and Vector Assembling.- Gene Transfer into Eukaryotic Cells.- Plasmid DNA Manufacturing.- Quality Assurance and Quality Control for Viral Therapeutics.- Analytical Assays to Characterise Adenoviral Vectors and Their Applications.- Validation of Gene Therapy Manufacturing Processes: A Case Study for Adenovirus Vectors.- Gene Delivery.- Regulatory Issues in Gene Therapy. Good Science - Good Sense.- Regulatory Aspects in Gene Therapy: Special Highlights on European Regulation.- Regulatory Issues for Process Development and Manufacture of Plasmids Under Contract.- Risk Assessment in Gene Therapy.
Table of ContentsSomatic Gene Therapy, Paradigm Shift or Pandora's Box: A Perspective on Gene Therapy; M. Lawler. Gene Therapy for Cancer: Deceiving the Malignant Cell; M. Lawler. Gene Self-Assembly (GENSA): Facilitating the Construction of Genes and Vectors; C.P. Hodgson. Gene Expression; J. Kaur, et al. Tumour Genotype and Response to Cytotoxic Gene Therapy; P.T. Daniel, et al. Protein Binding Matrices: Tools for Phenol-free Cloning and Vector Assembling; V.I. Evtushenko. Gene Transfer into Eukaryotic Cells; M. Weber. Plasmid DNA Manufacturing; M. Schleef, et al. Quality Assurance and Quality Control for Viral Therapeutics; S.S. Kuwahara. Analytical Assays to Characterise Adenoviral Vectors and Their Applications; E. Lehmberg, et al. Validation of Gene Therapy Manufacturing Processes: A Case Study for Adenovirus Vectors; D. Vacante, et al. Gene Delivery; A. Anand. Regulatory Issues in Gene Therapy. Good Science - Good Sense; N. Chew, J.A. Cavagnaro. Regulatory Aspects in Gene Therapy: Special Highlights on European Regulation; O. Cohen-Haguenhauer. Regulatory Issues for Process Development and Manufacture of Plasmids Under Contract; J.M. Jenco. Risk Assessment in Gene Therapy; A. Anand, S.K. Arora. Index.
