Pharmacy / dispensing Books
Elsevier Health Sciences Differential Diagnosis for Nonmedical Prescribers
Book Synopsis
£31.34
John Wiley & Sons Inc Thermodynamics of Pharmaceutical Systems
Book SynopsisDesigned for pharmacy students Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-needed introduction to the mathematical intricacies of thermodynamics in relation to practical laboratory applications. Designed to meet the needs of the contemporary curriculum in pharmacy schools, the text makes these connections clear, emphasizing specific applications to pharmaceutical systems including dosage forms and newer drug delivery systems. Students and practitioners involved in drug discovery, drug delivery, and drug action will benefit from Connors'' and Mecozzi''s authoritative treatment of the fundamentals of thermodynamics as well as their attention to drug molecules and experimental considerations. They will appreciate, as well, the significant revisions to the Second Edition. Expanding the book''s scope and usefulness, the new edition: Explores in greater depth topics most relevantTable of ContentsPREFACE. PREFACE TO THE FIRST EDITION. 0. Review of Mathematics. 0.1. Introduction. 0.2. Dimensions and Units. 0.3. Logarithms and Exponents. 0.4. Algebraic and Graphical Analysis. 0.5. Dealing with Change. 0.6. Statistical Treatment of Data. Problems. I BASIC THERMODYNAMICS. 1. Energy and the First Law of Thermodynamics. 1.1. Fundamental Concepts. 1.2. The First Law of Thermodynamics. 1.3. The Enthalpy. Problems. 2. The Entropy Concept. 2.1. The Entropy Defined. 2.2. The Second Law of Thermodynamics. 2.3. Applications of the Entropy Concept. Problems. 3. The Free Energy. 3.1. Properties of the Free Energy. 3.2. The Chemical Potential. Problems. 4. Equilibrium. 4.1. Conditions for Equilibrium. 4.2. Physical Processes. 4.3. Chemical Equilibrium. Problems. II THERMODYNAMICS OF PHYSICAL PROCESSES. 5. Introduction to Physical Processes. 5.1. Scope. 5.2. Concentration Scales. 5.3. Standard States. Problems. 6. Phase Transformations. 6.1. Pure Substances. 6.2. Multicomponent Systems. Problems. 7. Solutions of Nonelectrolytes. 7.1. Ideal Solutions. 7.2. Nonideal Solutions. 7.3. Partitioning Between Liquid Phases. Problems. 8. Solutions of Electrolytes. 8.1. Coulombic Interaction and Ionic Dissociation. 8.2. Mean Ionic Activity and Activity Coefficient. 8.3. The Debye–Hückel Theory. Problems. 9. Colligative Properties. 9.1. Boiling Point Elevation. 9.2. Freezing Point Depression. 9.3. Osmotic Pressure. 9.4. Isotonicity Calculations. Problems. 10. Solubility. 10.1. Solubility as an Equilibrium Constant. 10.2. The Ideal Solubility. 10.3. Temperature Dependence of the Solubility. 10.4. Solubility of Slightly Soluble Salts. 10.5. Solubilities of Nonelectrolytes: Further Issues. Problems. 11. Surfaces and Interfaces. 11.1. Thermodynamic Properties. 11.2. Adsorption. Problems. III THERMODYNAMICS OF CHEMICAL PROCESSES. 12. Acid–Base Equilibria. 12.1. Acid–Base Theory. 12.2. pH Dependence of Acid–Base Equilibria. 12.3. Calculation of Solution pH. 12.4. Acid–Base Titrations. 12.5. Aqueous Solubility of Weak Acids and Bases. 12.6. Nonaqueous Acid–Base Behavior. 12.7. Acid–Base Structure and Strength. Problems. 13. Electrical Work. 13.1. Introduction. 13.2. Oxidation–Reduction Reactions. 13.3. Electrochemical Cells. 13.4. pH Measurement. 13.5. Ion-Selective Membrane Electrodes. Problems. 14. Noncovalent Binding Equilibria. 14.1. Introduction. 14.2. The Noncovalent Interactions. 14.3. Binding Models. 14.4. Measurement of Binding Constants. 14.5. Applications. Problems. APPENDIXES. Appendix A Physical Constants. Appendix B Kinetic Theory of Gases. Appendix C Extrathermodynamic Relationships. ANSWERS TO PROBLEMS. BIBLIOGRAPHY. INDEX.
£83.66
Elsevier Health Sciences The Unofficial Guide to Prescribing
Book SynopsisLays out the practical steps of how to assess, investigate and manage a patient, with a focus on what to prescribe and how to prescribe it. This title aims to empower newly graduated junior doctors to excel at dealing with emergencies and handling complex prescribing scenarios.Trade Review"As part of 'The Unofficial Guide to.' series, this excellent book is a must have for all students, as well as professionals involved in prescribing and hospital care - it provides a solid foundation for dealing with emergency situations and complex prescribing scenarios. It strengthens theoretical knowledge and applies it to 'real life' situations...it is an essential resource that should hold a place on all university reading lists".Reviewed by: Dr Irfan Rashid on behalf of the International Journal of Clinical Skills, Jan 2015Table of Contents1 Introduction to prescribing. 2 Cardiology. 3 Respiratory medicine. 4 Gastroenterology. 5 Neurology. 6 Endocrinology. 7 Obstetrics and gynaecology. 8 General surgery. 9 Paediatrics. 10 Additional important scenarios.
£28.49
Elsevier Health Sciences Research Methods in Pharmacy Practice
Book SynopsisTable of ContentsPART 1 INTRODUCTION 1 Introduction to research in pharmacy practice 2 Planning your research 3 Levels of Measurement PART 2 QUANTITATIVE RESEARCH: DATA COLLECTION & ANALYSIS 4 Introduction to quantitative research 5 Validity and reliability: How do you know you are measuring what you think you are measuring? 6 Planning a survey, designing your questionnaire, and setting up a database 7 Participants in your research 8 Experimental design and randomised controlled trials: deciding what treatment works 9 Managing your results: a step-by-step guide to the principles underpinning your choice of the right statistics to use 10 Descriptive statistics: how many people said what and who were they? 11 Inferential statistics PART 3 QUALITATIVE RESEARCH: DATA COLLECTION & ANALYSIS 12 Introduction to Qualitative Research 13 Qualitative interviewing 14 Focus Groups 15 Observational Methods 16 Data analysis and coding 17 Data synthesis and presentation of findings 18 Other qualitative methods PART 4 MIXED METHODS RESEARCH 19 Multimethod, or "Mixed-Methods" Research PART 5 CONCLUSIONS 20 Research Outputs and Knowledge Translation 21 Conclusions - for just getting started
£30.39
Elsevier Health Sciences Pharmacy Practice
Book SynopsisTrade ReviewFrom customer reviews of the previous edition: 'A great book. Everything is well organised and easy to understand. Covers all topics an undergraduate pharmacy student would need . useful for a practising pharmacist too.' 'This is an excellent introduction to pharmacy practice. It is an excellent read. Very well worth buying if you are a pharmacist or chemist.' 'I'm a final year medical student and found this great for all those learning outcomes that are really difficult to find. Things like details on the yellow card scheme and MHRA that I'd previously spent hours searching for - a concise, clear explanation of can be found here. There are also useful things like consent, capacity, health-behaviour models, prescription writing, controlled drugs and homeopathy information . mops up the learning outcomes that most other books don't cover. I've used it most for the practise drugs calculations as we have formatives on these and end of year OSCEs too!'Table of ContentsSection 1: The Patient Socio-behavioural aspects of health and illness Socio-behavioural aspects of treatment with medicines Communication skills for pharmacists and their team Consent History Taking/ Gathering Information Concordance Advice giving and the pharmacist as a health trainer Section 2: The Medicine Control of medicines The prescribing process and evidence-based medicine Drug evaluation and pharmacoeconomics Formularies in pharmacy practice Complementary and alternative medicines Using calculations in pharmacy practice Veterinary pharmacy Section 3: The Medicine Formulation Dispensing techniques (compounding and good practice) Oral unit dosage forms Packaging Solutions Suspensions Emulsions External preparations Suppositories and pessaries Powders and granules Section 4: The Specialized Pharmacy Product Production of sterile products Parenteral products Opthalmic products Inhaled products Parenteral nutrition and dialysis Radiopharmacy Specialized services Appliances Section 5: The Pharmacy Safety Process Clinical governance Risk management Standard operating procedures Audit Information retrieval in pharmacy practice Control of health professionals and their staff Continuing professional development and revalidation Section 6: The role of pharmacy in healthcare The role of pharmacy in healthcare Ethics - the theory Ethics in practice and ethical dilemmas Public health Structure and organization of pharmacy Intra- and inter-professional working Section 7: The patient, their medicine and beyond The prescription Patient charges of medicines and their impact on access Routes of administration and dosage forms Labelling of dispensed medicines Monitoring the patient The role of the pharmacist in medicines optimisation Public health and pharmacy interventions Substance use and misuse
£57.94
Elsevier Health Sciences Practical Paediatric Prescribing
Book SynopsisTable of ContentsAbidec® Acetazolamide Acetylcysteine Aciclovir Adrenaline (epinephrine) Amiloride Aminophylline and theophylline Amitriptyline Amoxicillin Second-generation antihistamines Atenolol Atropine Azithromycin Baclofen Beclometasone dipropionate Calcium Captopril Carbamazepine Carobel Cefotaxime Ceftriaxone Cefuroxime Chloral hydrate Chlorphenamine Ciclosporin Ciprofloxacin Clarithromycin Clobazam Codeine phosphate Colomycin Desmopressin Dexamethasone Digoxin Dobutamine Docusate Domperidone Dopamine Dornase alfa (DNAse) Erythromycin Ethosuximide Fluticasone Furosemide Gabapentin Gastrografin® Gaviscon® Gentamicin Glycopyrronium bromide (glycopyrrolate) Heparin (unfractionated) Hydrocortisone Hyoscine hydrobromide Hypertonic saline Ibuprofen Insulin Ipratropium bromide Iron (ferrous sulfate, ferrous fumarate, sodium feredetate) Isoniazid Ketamine Lactulose Lamotrigine Levetiracetam Levothyroxine sodium Lidocaine Low-molecular-weight heparin (LMWH) Magnesium Mannitol Melatonin Meropenem Methylphenidate (Ritalin®, Medikinet®, Concerta XL®, Equasym XL®) Methotrexate Methylprednisolone Metronidazole Midazolam Montelukast Morphine Macrogols Omalizumab Omeprazole Ondansetron Oxybutynin hydrochloride Paracetamol Paraldehyde Phosphate (enema and supplements) Piperacillin with tazobactam (Tazocin®) Prednisolone Propranolol Ranitidine Rifampicin Salbutamol Salmeterol Senna Sodium picosulfate Sodium valproate Spironolactone Surfactant: pulmonary Tacrolimus Tobramycin Tranexamic acid Trimethoprim Vitamin D Vitamin K (Phytomenadione) Warfarin Appendix 1 Appendix 2 Appendix 3
£25.64
Elsevier Health Sciences Pass the PSA
Book SynopsisTrade ReviewFrom customer reviews of the previous edition: 'Brilliant Book. I passed the PSA at 96% and was in the top 0.5% of the country.' 'Buy this book for the PSA, fantastic book, straight to the point.' 'Must-have book for the PSA, can enter the exam with so much more confidence knowing roughly what format/common things to know.' 'Excellent - really well-written book. short and sweet. Has all the important drugs, SE, interactions etc. prepares you well for the PSA (and other prescribing exams)' 'Brilliant book'Table of Contents1 Basic principles of prescribing 2 Prescription review: A foolproof plan 3 Data interpretation 4 Planning management 5 Communicating information 6 Calculation skills 7 Prescribing: Doing it yourself 8 Drug monitoring 9 Adverse drug reactions 10 Mock examinations
£35.14
Elsevier Health Sciences Dales Pharmacology Condensed
Book SynopsisTable of ContentsSection 1: Pharmacology and Drug Use 1 Preface 2 Pharmacology, Drug Names, and Classification Systems Section 2: Fundamentals of Pharmacology 3 General Principles of Drug Action 4 Molecular Aspects of Drug Action 5 Pharmacokinetic and Other Factors Influencing Drug Action 6 Pharmacodynamics and the Measurement of Drug Action Section 3: Drug Development 7 Drug Discovery and the Development of Small Molecules 8 Drug Discovery and the Development of Biologicals 9 Drug Safety, Toxicology, and Pharmacovigilance 10 Regulation of Drug Use Section 4: Drug Actions on Body Systems 11 Outline of Transmission and Drug Action in the Nervous System 12 Drugs and Neurological Disorders 13 Drugs and Pain 14 Drugs and the Cardiovascular System 15 Drugs and Blood: Haematopoiesis and Haemostasis 16 Drugs and the Inflammatory and Immune Response 17 Drugs and the Endocrine and Metabolic Systems 18 Drugs and the Renal System 19 Drugs and the Pulmonary System 20 Drugs and the Musculoskeletal System 21 Drugs and the Gastrointestinal System 22 Drugs and the Kidney and Genitourinary System 23 Drugs and the Skin 24 Drugs and the Eye 25 Drugs and the Ear 26 Drugs Used in Anaesthesia 27 Drug Use in Disorders of Nutrition 28 Drug Use in Dentistry Section 5: Drugs to Treat Infectious Diseases and Neoplasms 29 Antiviral Drugs 30 Antibacterial Drugs 31 Antifungal Drugs 32 Drugs and Parasites: Anti-protozoal and Antihelminthic Drugs 33 Drugs and Cancer Section 6: Drugs in the Community 34 Prescribing and Personalising Drug Treatments 35 Venoms, Toxins, Poisons, and Herbs 36 Drug Dependence and Drug Abuse
£30.39
Elsevier Health Sciences Aultons Pharmaceutics
Book SynopsisTable of ContentsPreface ....................................................................... vii Contributors ............................................................. ix Acknowledgements .................................................. xiii What is 'pharmaceutics'?......................................... xv Kevin M.G. Taylor and Michael E. Aulton 1. Design of dosage forms.................................. 1 Peter York 2. Dissolution and solubility ............................. 13 Michael E. Aulton 3. Properties of solutions ................................... 30 Michael E. Aulton 4. Surfaces and interfaces ................................... 39 Graham Buckton 5. Disperse systems.............................................. 50 David Attwood 6. Rheology........................................................... 81 Christopher Marriott 7. Kinetics ............................................................. 101 Gareth R. Williams and John P. Malkinson 8. Solid-state properties .................................... 114 Graham Buckton 9. Particle size analysis ..................................... 126 Kevin M.G. Taylor 10. Particle size reduction and size separation....................................................... 143 Michael E. Aulton 11. Mixing............................................................. 156 Andrew M. Twitchell 12. Powder flow................................................... 172 Michael E. Aulton 13. Fundamentals of microbiology................... 184 Lara-Marie Barnes and Geoffrey W. Hanlon 14. Pharmaceutical applications of microbiological techniques.......................... 208 Lara-Marie Barnes and Norman A. Hodges 15. Action of physical and chemical agents on microorganisms....................................... 229 Lara-Marie Barnes, Geoffrey W. Hanlon and Norman A. Hodges 16. Principles of sterilization ............................. 247 Susannah E. Walsh, Katie Laird and Jean-Yves Maillard 17. Sterilization in practice ................................ 257 Jean-Yves Maillard, Katie Laird and Susannah E. Walsh 18. Introduction to biopharmaceutics.............. 275 Marianne Ashford and Kevin M.G. Taylor 19. Gastrointestinal tract e physiology and drug absorption............................................. 279 Marianne Ashford and Kevin M.G. Taylor 20. Bioavailability e physicochemical, dosage form and formulation factors ........ 297 Marianne Ashford, Kevin M.G. Taylor and Hala M. Fadda 21. Assessment of biopharmaceutical properties ....................................................... 320 Marianne Ashford and Kevin M.G. Taylor 22. Dosage regimens ........................................... 343 Soraya Dhillon and Nkiruka Umaru 23. Pharmaceutical preformulation .................. 360 Simon Gaisford 24. Solutions ........................................................ 386 Sudaxshina Murdan 25. Clarification ................................................... 397 Andrew M. Twitchell 26. Suspensions ................................................... 407 Susan A. Barker 27. Emulsions and creams ................................. 424 Gillian M. Eccleston 28. Ointments, pastes, gels, cutaneous patches and topical sprays........................... 453 Majella E. Lane 29. Powders, granules and granulation ............ 463 Michael E. Aulton 30. Drying............................................................. 483 Michael E. Aulton and Satyanarayana Somavarapu 31. Tablets and compaction............................... 501 Göran Alderborn and Göran Frenning 32. Modified-release oral drug delivery ............ 542 Emma L. McConnell, Christine M. Madla and Abdul W. Basit 33. Coating of tablets and multiparticulates ... 558 Stuart C. Porter 34. Continuous manufacturing of tablets ........ 574 Aktham Aburub and Hala M. Fadda 35. Hard capsules ................................................ 586 Brian E. Jones 36. Soft capsules .................................................. 599 Stephen Tindal 37. Dissolution testing of solid dosage forms............................................................... 612 Ana Cristina Freire, Francesca K.H. Gavins and Abdul W. Basit 38. Parenteral drug delivery ............................... 626 Robert Lowe 39. Pulmonary drug delivery ............................. 641 Kevin M.G. Taylor 40. Nasal drug delivery....................................... 658 Gary P. Martin and Alison B. Lansley 41. Ocular drug delivery..................................... 677 Hala Fadda, Ashkan Khalili, Peng Tee Khaw and Steve Brocchini 42. Otic drug delivery ......................................... 701 Xu Liu, Hugh Smyth and Feng Zhang 43. Topical and transdermal drug delivery ...... 713 Adrian C. Williams 44. Rectal and vaginal drug delivery................. 735 Kalliopi Dodou 45. Preparation and delivery of biopharmaceuticals....................................... 752 Ijeoma F. Uchegbu and Andreas G. Schätzlein 46. Pharmaceutical nanotechnology and nanomedicines .............................................. 768 Yvonne Perrie 47. Radiopharmaceuticals................................... 789 Neil Hartman and Margaret Cooper 48. The formulation and manufacture of plant medicines............................................. 805 G. Brian Lockwood 49. Design and administration of medicines for paediatric and geriatric patients............ 818 Catherine Tuleu, Mine Orlu and David Wright 50. Packaging ....................................................... 833 Sudaxshina Murdan 51. Chemical stability in dosage forms............ 848 Andrew R. Barnes and Mark Santillo 52. Microbial contamination, spoilage and preservation of medicines............................ 860 Norman A. Hodges and Lara-Marie Barnes 53. Product stability and stability testing......... 871 Paul Marshall 54. Pharmaceutical quality: the application of pharmaceutics in medicines regulation ....................................................... 894 Kevin M.G. Taylor, Majella E. Lane and Khalid A. Sheikh Self-assessment questions Sudaxshina Murdan Please check your eBook at https://studentconsult. inkling.com/ for self-assessment questions. See inside cover for registration details. Index.......................................................................... 915
£50.39
Paradigm Education Solutions Pharmacy Calculations for Technicians Text
Book SynopsisWith Pharmacy Calculations for Technicians, students learn the essential mathematics concepts and skills pharmacy technicians use on the job. Clear, complete examples and practice problems guide students in learning the skills required for calculating and preparing drug doses in both community and institutional pharmacy settings.
£95.40
CRC Press Quantitative Structure Activity Relationship
Book SynopsisGenerally speaking, quantitative-structure activity relationship (QSAR) is a technique which correlates the biological activities of a set of compounds to their structures using a mathematical equation represented in its general form by Biological Activity = f (x1, ..., xn), where f is a mathematical function and x1, ..., xn are n molecular descriptors. Since the introduction of the initial concept of QSAR in the early 1960s, numerous advances have been introduced into the field transforming it into an essential tool in drug discovery and medicinal chemistry. Quantitative Structure Activity Relationship: A Practical Approach provides a detailed overview of computational approaches in QSAR studies. It covers the applications of different algorithms in various steps of a QSAR analysis and shows clear examples. Each chapter introduces the tools and software involvedTable of Contents1. QSAR at a Glance 2. Database and Dataset 3. Molecular Descriptors 4. Descriptor Selection 5. Model Building 6. Validation of QSAR Models 7. Practical Example 8. Concluding Remarks
£171.00
Pharmaceutical Press Pharmaceutical Statistics
Book SynopsisWritten specifically for pharmacy students, this book explains basic statistics. It contains chapters on basic concepts such as types of data, graphical representation of data, distribution and standard deviation. More advanced statistical techniques, such as ANOVA, are also discussed.Trade Review'This book is a welcome addition to the Pharmacy library...an undoubted strength of the book is its clarity in presentation...the book is highly recommended to any person interested in quantitative aspects of pharmacy...' Prof. Mike Roberts, the Department of Medicine, Department of Practice and Policy, Princess Alexandra Hospital, The University of Queensland, Australia, Journal of Pharmacy and Pharmacology, 1 May 2003 -- Mike Roberts * Journal of Pharmacy and Pharmacology *'Pharmaceutical Statistics is well thought out and well written, with a good layout that does not get bogged down with overly complex explanations.' Henry Skupek, Program Support Coordinator, Australian College of Pharmacy Practice, Canberra, Australian Pharmacist, 1 Feb 2003 -- Henry Skupek * Australian Pharmacist *'...the book is a useful addition to the range of books available on pharmaceutical statistics.' Alain Li Wan Po, The Pharmaceutical Journal, 7 June 2003 -- Alain Li Wan Po * The Pharmaceutical Journal *
£31.35
Pharmaceutical Press Pharmaceutical Calculations Workbook
Book SynopsisThis is a companion self-study aid to Introduction to Pharmaceutical Calculations for practising calculations similar to those that may be presented in pharmacy examinations and in practice.Trade Review'Pharmaceutical Calculations Workbook provides a source of practice problems for students desiring more preparation, as well as providing a self-assessment resource to assure basic pharmacy calculations skills.' Ann Zweber, BPharm, Oregon State University. American Journal of Pharmaceutical Education. v.70(5); Oct 15, 2006 -- Ann Zweber * American Journal of Pharmaceutical Education *
£25.65
Pharmaceutical Press Introduction to Renal Therapeutics
Book SynopsisThis work gives an introduction to all aspects of drug use in renal failure.Introduction to Renal Therapeutics is an introduction to all aspects of drug use in renal failure. Covering various diseases affecting the kidneys, each chapter discusses the disease process and treatment. It also addresses the role of the pharmacist in patient care. Case studies and questions and answers are included at the end of each chapter.Written by members of the UK Renal Pharmacy Group, this book will be of particular interest to anyone new to, or planning a career in, renal pharmacy. It will also be of interest to nonspecialists who deal with renal patients and to pharmacy students, and to any healthcare professional with an interest in renal medicine.Trade Review'The book is organized so that any topic can be referenced easily and individual chapters are structured so that information is provided in a logical and clear format. This is a useful reference for pharmacists working with renally impaired patients. It outlines some of the major challenges encountered in clinical practice when treating these patients. The chapters are organized nicely with topic headings and tables highlighting key concepts, and succeeds in capturing clinically pertinent topics in renal medicine today.'Melissa M. Ranieri, BS, PharmD (Temple University School of Pharmacy) Doody Enterprises, Inc. March 2008 -- Melissa M. Ranieri * Doody's Notes *'The text offers a good overview of the issues pertinent to chronic kidney disease. Introduction to Renal Therapeutics provides a broad overview of the diseases and complications commonly associated with chronic kidney diseases and will be of interest to pharmacists and pharmacy students not familiar with nephrology.'Marianna Leung, BSc Pharm, PharmD CHJP Vol. 61, No. 4 July- August 2008 -- Marianna Leung * CHJP *'This book will be of value to anyone interested in expanding his or her knowledge about drug therapy for the renally impaired patient. The devotion of separate chapters to complications such as renal bone disease encourages the reader to fully explore the nuances of these conditions and their drug therapy.'Hillary Wall Grillo PharmD, The Annals of Pharmacotherapy Volume 42 July/ August 2008 -- Hillary Wall Grillo * The Annals of Pharmacotherapy *Table of Contents1. Introduction; 2. Laboratory Tests and Investigations; 3. Acute Renal Failure; 4. Chronic Kidney Disease; 5. Renal Anaemia; 6. Renal Bone Disease; 7. Hypertension / Hyperlipidaemia; 8. Renal Replacement Therapy; 9. Renal Transplantation; 10. Drug Dosing in Patients with Renal Impairment; 11. Drug Induced Kidney Failure; 12. Autoimmune Kidney Disease; 13. Paediatric Kidney Disease; 14. Renal Pharmacy in Critical Care; 15. Pain Control in Renal Impairment; 16. Diabetes Management in Kidney Disease; 17. Myeloma and Kidney Disease; 18. Palliative care; 19. Dietary Management of Kidney Disease; 20. Travelling and Vaccines.
£34.20
Pharmaceutical Press An Introduction to Clinical Pharmaceutics
Book SynopsisConsiders the importance of pharmaceutics and pharmaceutical dosage form design by considering the clinical use of modern drugs. This book also considers the use and behaviour of dosage forms in different age groups and patient groups along with developments such as personalised therapies and genomics.Table of Contents1. Introduction; 2. Drugs and Excipients; 3. Oral Formulations; 4. Parenteral Formulations; 5. Adverse Reactions; 6. Pharmaceutics and the Neonate; 7. Pharmaceutics of Disease States; 8. Advanced Delivery Systems.
£25.65
Pharmaceutical Press Drugs and the Liver
Book SynopsisEnables the practitioner to assess liver function using biochemical markers, other tests, signs, symptoms and disease knowledge. This practical guide covers background information on liver function, the principles of drug use in liver disease and includes a section of worked examples of commonly asked questions.Trade Review'For those pharmacists involved in medication reviews, interpretation of liver function test results is an essential part of the process. This book provides an excellent explanation of each parameter and the limitations of using the results alone when assessing the degree of liver function.'Jackie Smith, a pharmaceutical advisor, Chemist and Druggist, October 2008 -- Jackie Smith * Chemist and Druggist *'This book combines all pertinent issues relating to liver dysfunction and medication use in one reference. The authors and contributors have done an excellent job to make the book a practical tool that can be used by clinicians when making therapeutic choices rather than merely presenting pharmacokinetic principles and expected alterations in liver disease.'Sharya Vaughan Bourdet, PharmD BCPS, The Annals of Pharmacotherapy Vol. 42, July/August 2008 -- Sharya Vaughan Bourdet * The Annals of Pharmacotherapy *'The book is written primarily for pharmacist clinicians, but it serves as a useful review for anyone who has an interest in drug metabolism and liver function...the thorough but easy to understand review of the liver anatomy and function is a highlight. This is a good read for those who need to brush up on these topics.'Patrick J. McDonnell, Temple University School of Pharmacy. Doody Enterprises, Inc. April 2008 -- Patrick J. McDonnell * Doody Enterprises *Table of ContentsPart 1 - Understanding Liver Function; 1. Introduction to the Anatomy of the Liver; 2. Functions of the Liver; 3. Causes of Liver Disease and Dysfunction; 4. Assessing Liver Function; Part 2 - Principles of Drug Use in Liver Disease; 5. Pharmacokinetics of Drugs in Liver Disease; 6. Undesirable Side Effects; Part 3 - Putting the Theory into Practice; 7. Applying the Principles - introduction; 8. Introducing the Aide Memoire; 9. Scenario 1 Choice of Analgesia; 10. Scenario 2 Choice of Anti-emetic; 11. Scenario 3 Choice of Anti-hyperlipidaemic Agent; 12. Scenario 4 Choice of Hormone Replacement Therapy (HRT); 13. Scenario 5 Choice of Contraceptive; Appendix 1 - Detailed Description of the Patient Cases; Appendix 2 - The Blank Aide Memoire Form.
£34.20
Pharmaceutical Press Pharmacy Case Studies
Book SynopsisHelps students to take an integral approach to pharmacy via a series of pharmacy cases. This book tests knowledge gained within the individual areas of law and ethics, pharmaceutics, pharmacology and pathology by examples, bringing together various areas taught on the degree course.Table of ContentsGastrointestinal; Cardiovascular; Respiratory; CNS; Infections; Endocrine; Obstetrics, Gynaecology and UTI; Malignant Disease; Nutrition and the Blood; Musculoskeletal and Joint; Eyes; ENT; Skin; Immunological / Vaccines; Liver Disease; Renal Disease; Paediatrics; Elderly.
£31.35
Pharmaceutical Press Foundation in Pharmacy Practice
Book SynopsisGives an introductory overview to pharmacy practice. This book is suitable for first year undergraduate students, providing a starting point for further study and is facilitated by regular signposting and referencing to specific texts. It also includes an easily navigated glossary of reference terms.Trade Review'This book is detailed enough to provide readers with a strong background in pharmacy practice and to serve as a useful reference for seasoned professionals. It is comprehensive guide to practice.'Richard P Berardi, RPh, BSc, MHA (Temple University Hospital) Doody Enterprises Sept 2008 -- Richard P Berardi * Doody's Notes *Table of ContentsWhat is Pharmacy Practice?; Structure and function of the NHS in England; An overview of community pharmacy - The role of the community pharmacist; past, present and future; An overview of hospital pharmacy; An overview of industrial sector pharmacy; Introduction to Medicines Management; An overview of the structure and function of the Royal Pharmaceutical Society of Great Britain; Essential Communication Skills for Pharmacists; Prescription types and legal requirements; Prescription interpretation and understanding; Packaging of medicines; Labelling of medicines; Extemporaneous dispensing: a beginner's guide; Compliance, adherence and concordance; Sale and supply of medicines: Risk and advice provision; Major Routes of Drug Administration; Glossary of common Pharmacy Practice terms.
£31.35
Pharmaceutical Press Lecture Notes in Pharmacy Practice
Book SynopsisA comprehensive study/revision guide which summarises the basic principles in pharmacy practice. It covers essential information in the following five sections: introduction to pharmacy; clinical pharmacy and pharmacotherapeutics; responding to symptoms in community pharmacy; pharmacy information and research; and pharmacy systems.Table of Contents1. Historical Perspectives: 2. Pharmacy Practice and the Healthcare System: 3. Medicine Presentation and Administration: 4. Medicine Safety: 5. Community Pharmacy Practice: 6. Dispensing Prescriptions: 7. Health Promotion: 8. Communication Skills and Patient Counselling: 9. Compliance, Adherence and Concordance: 10. Mathematical Principles of Drug Therapy: 11. Point-of-Care Testing: 12. Pharmaceutical Care Plans: 13. Medicine Action: 14. Clinical Pharmacokinetics: 15. Constipation and Diarrhoea: 16. Gastro-oesophageal Reflux Disease and Peptic Ulcer Disease: 17. Inflammatory Bowel Disease and Other Chronic Bowel Disorders: 18. Emesis: 19. Cardiovascular Disorders: 20. Hypertension: 21. Ischaemic Heart Disease: 22. Congestive Heart Failure: 23. Hyperlipidaemia: 24. Thrombosis: 25. Asthma, Chronic Obstructive Pulmonary Disorder and Allergic Rhinitis: 26. Schizophrenia: 27. Mood Disorders: 28. Anxiety Disorders: 29. Sleep Disorders: 30. Eating Disorders: 31. Pain Management and Fever: 32. Dementia and Alzheimer's Disease: 33. Parkinson's Disease: 34. Anti-infective Agents: 35. Human Immunodeficiency Virus Infection: 36. Viral Hepatitis: 37. Thyroid Disorders: 38. Diabetes Mellitus: 39. Menopause and Hormone Replacement Therapy: 40. Menstrual Cycle Disorders and Contraception: 41. Genito-urinary Disorders: 42. Cancer and Palliative Care: 43. Anaemia and Drug-induced Blood Dyscrasias: 44. Rheumatoid Arthritis: 45. Osteoarthritis and Gout: 46. Bone Disorders: 47. Skin Disorders: 48. Wound Management: 49. Drug Therapy in Geriatric Patients: 50. Drug Therapy in Paediatric Patients: 51.Drugs Used in Pregnancy and During Lactation: 52. Critical Care Therapeutics: 53. Recent Advances in Pharmacotherapy: 54. Colds and Influenza: 55. Eye: 56. Oral and Dental: 57. Foot: 58. Ear: 59. Musculoskeletal: 60. Abdominal Pain, Perianal and Perivulval Pruritus: 61. Travel Medicine: 62. Pharmacy Literature and Medicine Information: 63.Medical Writing: 64. Research Methodology: 65. Primary Care Health Services: 66. Community Pharmacy Management: 67. Hospital Pharmacy Services: 68. Formulary Systems: 69. Medicines Regulatory Affairs: 70. Quality Standards in Community Pharmacy Practice
£38.70
Pharmaceutical Press Research Methods for Pharmaceutical Practice and
Book SynopsisUsing a scientific approach, this title outlines a thorough process for conducting pharmaceutical practice and policy research and presents a theoretical and practical framework for research methods, supported by applications and examples.Trade Review"Although Research Methods for Pharmaceutical Practice and Policy was designed to be an introductory textbook for graduate students in the social and administrative sciences in pharmacy, this book will be useful to other groups, including faculty and researchers in this area, and professional program students who desire to learn more about this type of research. The book is scholarly in tone and exceptionally well referenced. The book is easy to read and makes extensive use of research that has been conducted in this field." David P. Zgarrick - ScienceDirect, 2011 -- David P. Zgarrick * ScienceDirect *"The editor has assembled a book that will take the reader through the steps of research from the conception of the research question through possible journals for submission...Individuals who are interested in teaching or performing research in the area of pharmacy practice and policy should consider obtaining this book as a resource for their library." Dean L. Arneson, PharmD, PhD, American Journal of Pharmaceutical Education Vol 75 (5), 2011 -- Dean L. Arneson * American Journal of Pharmaceutical Education *Table of Contents1. Scientific Approach to Pharmaceutical Practice and Policy Research 2. Conceptualizing Research 3. Operationalizing Research 4. Measurement Theory and Methods 5. Experimental Designs 6. Non-experimental Research 7. Sampling Methods 8. Systematic Review of Literature 9. Data Collection Methods 10. Survey Design 11. Statistical Analysis 12. Secondary Data Analysis: Administrative Data 13. Secondary Data Analysis: Commercial Data 14. Secondary Data Analysis: National Sample Data 15. Program Evaluation 16. Future of Pharmaceutical Policy Research
£34.20
Pharmaceutical Press Medicines Use Reviews
Book SynopsisMedicines Use Reviews: A practical guide provides evidence-based information, tips and guidance on how to conduct successful Medicines Use Reviews (MURs).Trade Review"I didn't expect Youssef's book to be as good as it is: very clear, covers topic from different points of view, brilliantly written."RLM, Day Lewis Pharmacy, July 2016
£25.65
Pharmaceutical Press Hospital Pharmacy
Book SynopsisHospital Pharmacy outlines the changes in pharmacy practice within the hospital setting and discusses the vast range of services that are provided. Each chapter is devoted to an area of pharmacy practice and discusses its history, current practice and future developments.Trade Review"a book that details the features of pharmacy services within and from hospital-based pharmacies in the United Kingdom...This book certainly provides readers with a solid understanding of the practice of hospital-based pharmacy in the U.K." Patrick McDonnell, Pharm.D. (Temple University School of Pharmacy) -- Patrick J. McDonnellTable of Contents1. Hospital Pharmacy within the NHS 2. Pharmacy in the acute independent sector 3. Purchasing medicines 4. Medicines supply and automation 5. Controlled drugs in hospital pharmacy 6. Technical services 7. Quality assurance 8. Medicines iInformation 9. Clinical pharmacy 10. Pharmacist prescribing 11. Strategic medicines management 12. Risks with medicines 13. Mental health pharmacy 14. Community health services 15. Information technology 16. Research and development 17. Workplace development 18. Consultant pharmacists 19. Managing services
£31.50
Pharmaceutical Press Handbook of Extemporaneous Preparation
Book SynopsisA comprehensive and easy-to-follow guide to good practice in extemporaneous compounding.Trade Review"...this resource offers a real advantage to both the prescriber and the pharmacist in the provision of quality oral liquids...Of particular use and unique to this text is the inclusion of a 'risk assessment' section in each monograph which addresses the clinical and technical risks associated with the extemporaneous preparation of each oral liquid...This book is not only a useful resource, but a valuable addition to the texts available on extemporaneous dispensing for those prescribers wanting quick access to suitable oral liquid alternatives..." Alison Haywood, Senior Lecturer, Griffith University, and Beverley Glass, Professor of Pharmacy, James Cook University Queensland, Australian Prescriber 34(5), October 2011. -- Alison Haywood * Australian Prescriber *Table of ContentsPart A - Standards 1. Glossary 2. Introduction 3. Risk Management 4. Quality Management 5. Personnel & Training 6. Premises & Equipment 7. Documentation 8. Preparation 9. Formulation & Stability 10. Quality Control 11. Complaints, Product Recalls & Adverse Events 12. Procurement & Quality Assessment 13. Audit & Monitoring Part B Extemporaneous Preparation Formulary 14. Introduction 15. Data Collection 16. Risk Assessment 17. Formulary of Extemporaneous Preparation
£43.20
Pharmaceutical Press Pharmaceutical Compounding and Dispensing
Book SynopsisThis is a modern, detailed and practical guide to the theory and practice of extemporaneous compounding and dispensing. Fully revised and updated, this new edition will be an indispensable reference for pharmacy students and practicing pharmacists.Trade Review"The book is well received, since there are few textbooks or reference books available devoted specifically to compounding. The authors should be commended for emphasizing the historical content in tandem with the preparation instruction...the book remains a good resource for anyone interested in compounding" Christine R. Birnie, PhD, American Journal of Pharmaceutical Education 75(1), Feb 2011 -- Christine R. Birnie * American Journal of Pharmaceutical Education *
£38.70
Pharmaceutical Press MCQs in Pharmaceutical Science and Technology
Book SynopsisMCQs in Pharmaceutical Science and Technology includes 600 MCQs progressing from basic science through to clinical considerations.
£31.35
Pharmaceutical Press Essentials of Pharmaceutical Chemistry
Book SynopsisEssentials of Pharmaceutical Chemistry is an introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. It covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules.Trade Review "...Donald Cairns is a well-known educator, mentor, and researcher...this is an excellent resource for pharmacy students taking pharmaceutical chemistry and for individuals who intend to pursue a career in the pharmaceutical industry...Readers will find this as a useful reference." Rahmat M Talukder, Ph.D.,Doody's Notes, May 2012. -- Rahmat M Talukder * Doody's Notes *"This is a great book detailing the basic chemistry of drugs...Throughout the book there are problems that can be worked, and it includes the answers at the end of the book. It is very easy-to-read and has very good graphics to support the discussions. In addition to being a good text, it is a good refresher for those that would like to review this topic."Compounding Today, 27 Jan 2012. * Compounding Today *Table of Contents1. Chemistry of Acids and Bases; 2. Partition Coefficient and Biopharmacy; 3. Physicochemical Properties of Drugs; 4. Stereochemistry; 5. Drug Metabolism; 6. Volumetric Analysis of Drugs; 7. Analytical Spectroscopy; 8. Chromatographic Methods of Analysis; 9. Stability of Drugs and Medicines; 10. Kinetics of Drug Stability; 11. Licensing of Drugs and the British Pharmacopoeia; 12. Medicinal Chemistry - the Science of Rational Drug Design; 13. Answers to Problems
£38.70
Pharmaceutical Press Stockleys Herbal Medicines Interactions
Book SynopsisInvaluable reference text for all healthcare professionals who require evidence-based information on the interactions of conventional medicines with herbal medicines, dietary supplements and nutraceuticals.
£74.25
Pharmaceutical Press FASTtrack Pharmacology
Book SynopsisProvides a brief account of drug action, as a study or revision aid. The authors have taken a therapeutic area and considered the major classes of drugs, their actions and, to a limited degree, their uses.Trade Review"This book is intended to enhance material covered in traditional pharmacology textbooks...Visuals, algorithms, diagrams, and key points interspersed throughout the book help reinforce and summarize the material. Readers will be able to assess their understanding of the material through self-assessment questions at the conclusion of each chapter...Undergraduate pharmacy students, as well as other healthcare students, will find this a useful guide to help prepare for examinations." Neela A. Bhajandas, PharmD, Doody's Notes, May 2013. -- Neela A. Bhajandas * Doody's Notes *"The book provides good basic knowledge of pharmacology and is well organized, with sections on principles, followed by sections on the drugs used to treat different therapeutic areas...Overall the authors have generally obtained a good balance of core information that is accessible, without it being a textbook in disguise!...Whilst this book is aimed primarily at Pharmacists, I am sure it would also be of value as a revision aid for Medical students...my own daughter who is a 4th year Medical student said she would buy it, an endorsement indeed!" Professor Clive Page, British Journal of Pharmacology, June 2012 -- Professor Clive Page * British Journal of Pharmacology *Table of Contents1. Pharmacodynamics 2. Receptors 3. G-proteins and Their Downstream Signaling Cascades 4. Ion Channels and Transporters 5. Quantitive Pharmacology 6. Autonomic Pharmacology 7. Local Mediators 8. Pharmacokinetics and Drug Metabolism 9. Gastric Pharmacology 10. Lower Gastrointestinal Pharmacology 11. Antiemetics 12. Antiarrhythmics 13. Cardiovascular Drugs 14. Renal and Urinary Pharmacology 15. Antithrombotic Agents 16. Antiobesity Drugs 17. Asthma and Chronic Obstructive Pulmonary Disease 18. Allergy 19. Anxiolytics and Hypnotics 20. Antidepressants 21. Antiepileptic Drugs 22. Antipsychotic Drugs 23. Parkinson's Disease 24. Analgesics 25. Drugs of Abuse 26. General Anaesthetics 27. Neuromuscular Blocking Drugs 28. Thyroid Disorders 29. Diabetes Mellitus 30. Antibacterial Agents 31. Non-bacterial Infections 32. Anticancer Drugs 33. Steroids 34. Oral Contraceptives 35. Immunopharmacology 36. Biopharmaceuticals 37. Variation in Clinical Efficacy
£26.60
Pharmaceutical Press Remington Education Pharmaceutics
Book SynopsisRemington Education: Pharmaceutics covers the basic principles of pharmaceutics, from dosage forms to drug delivery and targeting. It addresses all the principles covered in an introductory pharmacy course. As well as offering a summary of key information in pharmaceutics, it offers numerous case studies and MCQs for self assessment.Trade Review"Many chapters include patient counselling tips, which should be helpful for students. Providing examples of marketed products based on the delivery technology discussed in the chapter makes the concept interesting and relevant... The fundamental theoretical and practical aspects of various drug delivery systems that this book presents will help students develop a solid understanding of the subject." Rahmat M. Talukder, PhD, RPh, Doody's Reviews, November 2014. -- Rahmat M Talukder * Doody's Review Service *Table of Contents1. Introduction to dosage form design; 2. Intermolecular forces and the physical and pharmaceutical properties of drugs; 3. Dispersed systems; 4. Properties of solutions and manipulation of solubility; 5. Chemical stability of drugs; 6. Drug travel from dosage form to receptor; 7. Bioavailability, bioequivalence and the Biopharmaceutical Classification System; 8. Parenteral drug delivery; 9. Delivery of biopharmaceuticals and the use of novel carrier systems; 10. Drug delivery to the eye; 11. Drug delivery from the oral cavity; 12. Oral delivery of immediate release dosage forms; 13. Oral delivery of modified release solid dosage forms; 14. Rectal and vaginal drug delivery; 15. Nasal drug delivery; 16. Drug delivery to the lung and from the lung; 17. Drug delivery to the skin; 18. Transdermal dosage forms: drug delivery to the blood stream.
£31.35
Pharmaceutical Press FASTtrack Pharmaceutics Dosage Form and Design
Book SynopsisThis revision guide for students delivers the essentials of dosage formulation in a concise and easy-to-use format.Table of Contents1. Pharmaceutical solutions for administration to the gastrointestinal tract; 2. Pharmaceutical disperse systems 1: suspensions - general principles and the formulation of suspensions for oral administration; 3. Pharmaceutical disperse systems 2: emulsions and creams; 4. Pharmaceutical disperse systems 3: ointments, pastes, lotions, gels and related formulations; 5. Parenteral formulations; 6. Ocular, nasal and otic dosage forms; 7. Vaginal and rectal dosage forms; 8. Respiratory dosage forms; 9. Solid-dosage forms 1: tablets; 10. Solid-dosage forms 2: capsules; 11. Introduction to pharmaceutical engineering
£26.60
Pharmaceutical Press FASTtrack Chemistry of Drugs
Book SynopsisA revision guide on pharmaceutical and medicinal chemistry. The book covers all aspects of the chemistry of drugs and includes key points, tips, and self-assessment questions to aid in learning.Trade Review"4 stars. This book is a brilliant resource written by two experts in the field of pharmaceutical and medicinal chemistry. It is intended to complement lecture notes and prepare pharmacy undergraduates for their exams. It would also be a useful resource for practising pharmacists, researchers, scientists and all those with an interest in chemical structure and bonding, intermolecular interactions, drug licensing and pharmacopoeia. The text is well written, with a clear, consistent and open layout. There are overviews outlining what the reader should know after completing each section. The text is presented in concise bullet points, with key points, tips and simple diagrams." Oliver McGurk, medical science undergraduate, Nursing Standard 29(9) October 2014 -- Oliver McGurk * Nursing Standard *Table of Contents1. Chemical structure and bonding; 2. Intermolecular interactions; 3. Acids and bases; 4. Stereochemistry; 5. Chemical reaction mechanisms; 6. Chemistry of electrophiles and nucleophiles; 7. Chemistry of aromatic compounds; 8. Chemistry of carbonyl compounds; 9. Chemistry of aromatic heterocyclic compounds; 10. Amino acids, peptides and proteins; 11. Carbohydrates and nucleic acids; 12. Lipids and steroids; 13. Chemical stability of drugs; 14. Drug metabolism; 15. Molecular spectroscopy and pharmaceutical analysis; 16. Drug licensing and pharmacopoeia; Answers to self-assessment
£26.60
Pharmaceutical Press Making Medicines
Book SynopsisMaking Medicines is a concise, chronological discussion of the history of therapeutics and pharmacy from the Egyptians through to the present day. It focuses on the discovery and uses of medicines to treat illness through the ages, and the evolving role of the pharmacist.Trade Review'From the Egyptians to present-day, the reader will find a chronological discussion about the discovery and uses of medicines to treat illness. There are two sections that illustrate how pharmacy has developed and evolved over the years. Edited by Stuart Anderson, this book will appeal to a large audience and deliver unique content to you, the reader.'International Journal of Pharmaceutical Compounding, Volume 4. Issue 51. December 28, 2007 * International Journal of Pharmaceutical Compounding *'...an interesting read for the public, students, and those who want to find out more about the history of pharmacy. Although the title of the text suggested it was a "brief" history, it was clear to me that an extensive amount of information was compiled through many different resources.'Megan Thompson, Pharm.D. College of Pharmacy, University of New Mexico, Drug Development and Industrial Pharmacy, 32:909, 2006 -- Megan Thompson * Drug Development and Industrial Pharmacy *'Making Medicines merits a place in any library that shelves a historical collection about the field of health...'Pharmacy in History 48 (3), 148-149 * Pharmacy in History *Table of ContentsPart 1: The Development of Pharmacy: 1. Pharmacy in the Ancient World Up to 1231 AD: William Court; 2. Pharmacy in the Mediaeval World 1231 to 1617 AD: Juanita Burnby; 3. Pharmacy in the Early Modern World 1671 to 1841 AD: Peter M Worling; 4. Pharmacy in the Modern World 1841 to 1986 AD: John A Hunt; Part 2: The Practice of Pharmacy: 5. Pharmacy Education: Melvin Earles; 6. Retail Pharmacy Practice in UK: Peter G Homan; 7. Pharmacy Practice in Hospitals: Shirley Ellis; 8. The Growth of the Pharmaceutical Industry: Judy Slinn; Part 3: The Products of Pharmacy: 9. A History of Therapeutic Discovery: Walter Sneader, Viviane Quirke; 10. A History of Dosage Form: William A Jackson; 11. A History of Drug Safety: 12. From Secret Remedies to Prescription Medicines: Part 4: Pharmacy Today and Tomorrow: 13. Pharmacy Today: Nicholas Wood; 14. Pharmacy Tomorrow: David Taylor
£25.65
Pharmaceutical Press Remington Education Physical Pharmacy
Book SynopsisRemington Education: Physical Pharmacy provides a simple, concise view of the concepts and applications of physical pharmacy.Trade Review"The study of physical pharmacy often fills many students with trepidation but this book, published by Pharmaceutical Press, Royal Pharmaceutical Society, can help to alleviate this by providing a simple introduction to the topic. The author defines physical pharmacy as a subcategory of pharmaceuticals that focuses on the reasons that drug delivery systems behave as they do...The book is laid out in an easy to understand way, guiding the reader through each relevant component. By providing a summary of important information and including self-assessment questions and answers, the book offers a practical way for students to check knowledge and track progress before, during and after a course in physical pharmacy." Laurence A. Goldberg, The Pharmaceutical Journal, 22 December 2015 -- Laurence A. Goldberg * The Pharmaceutical Journal *Table of Contents1: Intermolecular Interactions; 2: Colligative Properties of Substances; 3: Solvents; 4: Solutions; 5: Interfacial Phenomena and Rheology; 6: Colloids; 7: Coarse Dispersions - Suspensions; 8: Coarse Dispersions - Emulsions; 9: Semisolid Drug Delivery Systems; 10: Powders and Granules; 11: Capsules; 12: Tablets; 13: Suppositories; 14: Transdermal Products; 15: Ophthalmic, Otic, Nasal Drug Delivery Systems; 16: Inhalation Drug Delivery System.
£34.20
Pharmaceutical Press Clinical Pharmacy Pocket Companion
Book SynopsisAn A-Z pocket book containing concise and practical pharmaceutical information for busy clinical pharmacists.Trade Review"The book can be described as having three main functions: an aide-memoire to resolve routine queries; a prompt to seek further information; and a means to record personal information by utilising blank spaces provided at the end of each entry and section... Although the topics are not presented in a standard format, each is well written and provides valuable information and relevant references... This book will be useful to any person delivering a clinical pharmacy service, either in a primary or secondary healthcare environment. It provides information on obscure problems, as well as routine queries... community pharmacists will find that the book has immense value in supporting their clinical activities, particularly when offering post-hospital discharge pharmaceutical care." Laurence A. Goldberg, The Pharmaceutical Journal, Feb 2016. -- Laurence A. Goldberg * The Pharmaceutical Journal *
£31.35
Pharmaceutical Press Handbook of Drug Administration via Enteral
Book SynopsisThe Handbook of Drug Administration via Enteral Feeding Tubes furnishes you with the background knowledge to inform clinical decision making as well as providing over 400 drug monographs.Trade Review"5 stars!...drug monographs are organized in a way that allows quick access to information and it is very easy to determine if the medication is safe to be administered through the enteral route. Information is current and properly referenced...This is a convenient and useful guide to have on the medical floor as a point of care reference for nurses, pharmacists, or any healthcare providers..." Melissa M. Ranieri, BS, PharmD, Doody's Notes, May 2015. -- Melissa M. Ranieri * Doody's Notes *Table of Contents1. Introduction; 2. Types of enteral feeding tubes; 3. Flushing enteral feeding tubes; 4. Restoring and maintaining patency of enteral feeding tubes; 5. Drug therapy review; 6. Choice of medication formulation; 7. The legal and professional consequences of administering drugs via enteral feeding tubes; 8. Health and safety and clinical risk management; 9. Syringes and ports; 10. Defining interactions; 11. Medicines optimisation; Individual drug monographs.
£50.40
Pharmaceutical Press Quality Assurance of Aseptic Preparation Services
Book SynopsisQuality Assurance of Aseptic Preparation Services Standards Handbook (also known as the Yellow Guide) provides standards for unlicensed aseptic preparation in the UK, as well as practical information to aid implementation of the standards.Table of ContentsPart A - standardsChapter 1 IntroductionChapter 2 Definitions/Glossary of termsChapter 3 Minimising risk with injectable medicinesChapter 4 Prescribing, clinical pharmacy and aseptic services verificationChapter 5 ManagementChapter 6 Formulation stability and shelf lifeChapter 7 Facilities and equipmentChapter 8 Pharmaceutical Quality SystemChapter 9 Personnel, training & competency assessmentChapter 10 Aseptic processingChapter 11 MonitoringChapter 12 Cleaning, sanitisation and biodecontaminationChapter 13 Starting materials, components and other consumablesChapter 14 Product approvalChapter 15 Storage and distributionChapter 16 Internal and external auditPart B – support resources1 Microbiological environmental monitoring techniques for the laboratory2 Validation of aseptic preparation procedures:2.1 Microbiological validation of the process2.2 Microbiological validation of the operator2.3 Product validation2.4 Validation of training2.5 Validation of cleaning processes2.6 Computerised system validation3 Technical (quality) agreements4 Products for short-term use – maximum shelf life 24 hours5 Capacity planning – technical services6 Advanced therapy medicinal products (ATMPs)
£41.40
Pharmaceutical Press Stockleys Drug Interactions
Book SynopsisStockley's Drug Interactions is still the most indispensible and authoritative international source of drug interaction information. Based upon the many thousands of published clinical papers and reports, it provides a series of detailed, yet concise, monographs designed for quick and easy reference.Trade Review"This incredibly detailed text is a must have for toxicologists who spend much time reviewing the known and potential effect of drugs when detected together......Like other Pharmaceutical Press publications (eg Clarke's Analysis of Drugs and Poisons) this quality publication provides an evidence based assessment of drugs and their interactions. The monographs are methodically set out providing the relevant clinical evidence of the drugs interaction, the mechanism, the significance of the findings as well as the management of clinical symptoms. All of the monographs are referenced with up to date reviews on available literature......contains in-depth yet concise monographs in an easy-to-read format and provides comprehensive details of the clinical evidence for the interactions under discussion, an assessment of their clinical importance, and clear guidance on managing the interaction in practice. The coverage of drugs is impressive, including drugs that are used around the world not just from a national jurisdiction......I can recommend this text for all toxicologists as it provides an authoritative and evidence based approach to documented drug interactions - an approach we should always maintain when interpreting our casework."Dimitri Gerostamoulos, TIAFT bulletin, 46(2) June 2016 -- Dimitri Gerostamoulos * TIAFT Bulletin *
£216.00
Pharmaceutical Press An Introduction to Clinical Pharmaceutics
Book Synopsis
£36.00
Springer London Ltd Cancer Chemotherapy in Clinical Practice
Book SynopsisA simple introduction explaining the broad principles underlying chemotherapy, this book gives trainees a framework within which they can place the specific aspects of cancer chemotherapy they encounter in their everyday experience.Table of Contents1. The Theoretical Basis of Cancer Chemotherapy.- 2. Practical aspects of chemotherapy.- 3. Part III: Chemotherapy in the management of cancer.
£40.49
Legare Street Press The Complete Herbalist
Book Synopsis
£30.35
Taylor & Francis Ltd Disaster and Emergency Pharmacy
Book SynopsisThis important book introduces pharmacists and pharmacy students to the basics of disaster and emergency management, illustrating not only the different roles that pharmacists can play within any disaster or emergency, but the practical steps they can take to prepare for these events. Starting with the UN-recognised Sendai Framework for disaster risk reduction, the book introduces the key concepts and models that pharmacists should understand, before detailing the place of pharmacists within each stage of an emergency or disaster. It also includes interviews with experts in disaster management, shedding light not only on the place of pharmacy within disaster and emergency management, but also the challenges and barriers involved in fulfilling this role. Concluding with practical advice and guidance, as well as how the lessons of disaster and emergency management can inform the everyday role of pharmacists within wider community healthcare, this will be essential readinTrade ReviewThis is exactly the multidisciplinary approach to crisis or disaster medicine I have spent my career teaching and advocating for….you are among the first scholars to accomplish such a level of multidisciplinary scholarship….just make sure it is marketed to all the professions….certainly should be on the shelf of every physician practicing disaster medicine! Dr Fredrick (Skip) Burkle Jnr- Professor (Ret.), Senior Fellow & Scientist, Harvard Humanitarian Initiative, Harvard University & T. H. Chan School of Public HealthTable of Contents1.Why a Disaster Pharmacy Researcher? My Autoethnography Narrative. Part I Introduction to Disaster and Emergency Management. 2.Definitions and Terminology. 3.Health Consequences of Emergencies. 4.Disaster Theories. 5.Disaster and Emergency Pharmacy Models. Part II Pharmacists’ Place in Disaster and Emergency Management. 6.History & Evolution of Pharmacists in Disasters and Emergencies. 7.PPRR Cycle & Pharmacists’ Roles. Part III Evidence from the Field. 8.Evidence from the Field: Disaster & Emergency Management Theme. 9.Story from the Field - An Interview with Dr Fredrick M. (Skip) Burkle Jr. 10.Community Theme. 11.Story from the Field - An Interview with Dr Robert Dunne. 12.Evidence from the Field: Pharmacy Theme. 13.Story from the Field - An Interview with Amanda Sanburg. 14.Evidence from the Field: Barriers and Enablers Theme. 15.Story from the Field - An Interview with Captain Tim Davis. Part IV Practical Guide for Pharmacists Working in Disasters and Emergencies. 16.Ethico-Legal Considerations. 17.How to Prepare for Disasters and Emergencies as Pharmacists and Pharmacy Students. 18.Teaching Disaster and Emergency Management in Pharmacy School. 19.Disasters and Emergencies that Change Us. 20.Conclusion
£28.49
Cambridge University Press Surviving Prescribing
Book SynopsisSafe and effective prescribing is one of the pillars of medical practice but is much more complicated than it seems. Many new prescribers find prescribing extremely challenging, and a plethora of independent, multidisciplinary prescribers are also seeking guidance. However, pharmacology textbooks are rarely practical. They warn to ''take care when prescribing erythromycin to a patient on warfarin, as the INR may rise''. But what should the prescriber actually do? Surviving Prescribing fulfils an important need by offering practical advice for real-world prescribing problems. The book complements existing educational resources but adds a new perspective. Written by experienced contributors from a variety of professional backgrounds, the content speaks directly to the problems routinely seen in hospital prescribing. And all in one, pocket-sized volume. Whether revising for the national Prescribing Safety Assessment, preparing for starting on the wards, or looking for a quick reference guTrade Review'Wow. This is a phenomenal piece of work. Excellent for medical students, specialty trainees and anyone prescribing outside specialty. It acknowledges both the complexity and risks of prescribing and provides a framework that spans pre-clinical pharmacology and prescribing at the bedside. I wish this book had been written 20 years ago. It's chatty and readable and will be an invaluable resource to students and doctors alike.' Dr Chris van Tulleken, Honorary Associate Professor, UCL, London'A valuable source of information and reference and a 'must read' text to support education and learning for prescribers in all health sectors.' Ian Bates, Professor of Pharmacy Education, UCL School of Pharmacy, London'Surviving Prescribing is a must have for new prescribers. An easy-to-use, practical guide to prescribing, it is full of useful tips and easy-to-remember acronyms, in a concise readable format. It will help the reader develop their knowledge of key therapeutic topics, calculation methods, serious drug interactions and electronic prescribing. The comprehensive content is primarily written for hospital-based prescribers though practitioners in care homes, general practice, domiciliary and other primary care settings will find much of the content useful too.' Nina L. Barnett, Consultant Pharmacist, London North West University Healthcare NHS Trust and NHS Specialist Pharmacy Service, and Visiting Professor, Kingston University, London'… it is probably best suited to a medical student on clinical rotations as an introduction to prescribing.' Sonya Shipley, Family MedicineTable of ContentsSection 1. Introduction; 1. The basics of safe drug use Yogini Jain; Section 2. Prescribing for patient groups; 2. Prescribing in renal disease Dipty Joshi; 3. Prescribing for children Abimbola Sanu; 4. Prescribing for older patients Shirley Ip; 5. Prescribing in pregnancy Alia Husain; 6. The basic principles of prescribing and breastfeeding Alia Husain; 7. Management of the delirious (acutely confused) patient Jim Bolton; 8. Prevention of delirium tremens and management of alcohol withdrawal syndrome Rob Shulman; Section 3. Emergency prescribing; 9. Diabetic ketoacidosis Lloyd E. Kwanten; 10. Hyperosmolar hyperglycaemic state Lloyd E. Kwanten; 11. Hypoglycaemia Lloyd E. Kwanten; 12. Paracetamol overdose Mayur Murali; 13. Emergency prescribing in cardiology Sebastian Vandermolen and David Brull; 14. Emergency prescribing in neurosurgery Sheetal Sumaria and Lindsey Stockford; 15. Respiratory emergencies Xolani Dereck Gondongwe; 16. Pulmonary embolism Rob Shulman; 17. Electrolyte and metabolic emergencies Ned Gilbert-Kawai; Section 4. Gastronintestinal; 18. Practical prescribing in general gastroenterology Angad Singh; 19. Constipation in the adult patient Angad Singh; 20. Nausea and vomiting Angad Singh; 21. Safe prescribing in liver disease Angad Singh; 22. Practical parental nutrition Laura Hyam and Angad Singh; Section 5. Central nervous system; 23. Analgesia Suparna Bali; 24. Patient controlled analgesia Suparna Bali; 25. Epidural analgesia Suparna Bali; 26. Fit for a fit: How to treat adults with seizures Lindsey Stockford and Sheetal Sumaria; 27. Pallative care prescribing Simon Noble; Section 6. Haemotology; 28. Warfarin prescribing Bridget Coleman; 29. Parenteral anticoagulation Rob Shulman; 30. Prescribing survival guide: Direct oral anticoagulants Rosalind Byrne and Alison Brown; Section 7. Surgery; 31. Practical prescribing in the surgical patient Mayur Murali; 32. Diabetes in surgery Jessal Mitual Palan; 33. Bowel preparation Mayur Murali; Section 8. Diabetes; 34. Treating diabetes Lloyd E. Kwanten and Miriam Conway; 35. Intravenous insulin infusions Lloyd E. Kwanten; Section 9. Calculations; 36. Calculations for the prescriber Gemma Wareing; 37. Therapeutic drug monitoring Nishma Gadher; Section 10. Interactions, hypersensitivity and contraindications; 38. Drug hypersensitivities and contraindications Roman Landowski; 39. Interactions that matter Roman Landowski; Section 11. Infections and other important topics; 40. Infections Peter Wilson; 41. Deprescribing Kat Le Bosquet; 42. Electronic prescribing Samrina Bhatti; 43. Corticosteriods Rob Shulman; 44. Intravenous therapy Rob Shulman; Index.
£21.99
Cambridge University Press Independent and Supplementary Prescribing
Book SynopsisWritten by a group of multi-professional authors, this fully updated third edition builds on the success of this classic text. The book explores a number of key areas for prescribers, including prescribing within a multidisciplinary team context, consultation skills, ethical and legal issues surrounding prescribing, the psychology and sociology of prescribing, and applied pharmacology. Among the other topics featured are monitoring skills, medicines concordance, evidence based prescribing, prescribing within a public health perspective, calculation skills, prescribing in dermatology, and minimizing the risk of prescribing errors. Each chapter has been revised and additional chapters on antimicrobial prescribing, education and training to become a prescriber, and a new section on renal impairment have been added. This book is an essential resource for both new and experienced prescribers and anyone undertaking the non-medical prescribing (NMP) programme including nurses, pharmacists, alTrade Review'I am delighted that the third edition of Independent and Supplementary Prescribing: An Essential Guide is now published. It all began with Neighbourhood Nursing report which I chaired in 1986, which was hugely valuable for community nurses, GPs, but above all the patients. With the strong support of The Royal College of Nursing, and others like Matt Griffiths and Molly Courtenay, it became embedded as an idea and a practice. Like all good ideas it grew, and other professions can now prescribe but healthcare changes fast and we must keep up-to-date. So, I warmly welcome this third edition building on the popularity of the first two. This book is essential reading for non-medical practitioners undertaking the prescribing course along with medical students learning to prescribe. With such valuable advice and educational materials the future is bright for better care for patients and skilled practitioners.' Baroness Julia Cumberlege, CBE, DL'This book offers good discussion on pertinent topics for prescribers, including good communication skills, ethical and legal issues, influences on prescribing habits, adverse drug reactions, drug interactions, research studies and statistical interpretation, and some useful information on disease states and prescribing for them.' Judith Klevan, Doody's ReviewsTable of Contents1. Non-medical prescribing: An overview Molly Courtenay and Matt Griffiths; 2. Non-medical prescribing in a multidisciplinary team context Barbara Stuttle, Sam Sherrington and Dianne Hogg; 3. Consultation skills and decision making Gary Morris and Anne Baird; 4. Legal aspects of independent and supplementary prescribing Mark Gagan; 5. Ethical issues in independent and supplementary prescribing Jo Taylor and John Adams; 6. Psychology and sociology of prescribing Angel Chater and Hannah Family; 7. Applied pharmacology Kat Hall and Michele Cossey; 8. Monitoring skills (asthma, diabetes, renal impairment) Sharon Sturney, Sian Bodman and Sally Haslam; 9. Promoting concordance in prescribing interactions Sue Latter; 10. Evidenced-based prescribing Gerry Morrow; 11. Independent/supplementary prescribing: A public health perspective Sarah O'Brien; 12. Calculation skills Alison Eggleton; 13. Prescribing in practice: How it works Polly Buchanan; 14. Minimising the risk of prescribing error Cate Whittlesea; 15. Prescribing for undergraduate students Rosemary Lim and Molly Courtenay; 16. Antimicrobial prescribing Enrique Castro-Sanchez.
£35.14
John Wiley and Sons Ltd Prescribing at a Glance
Book SynopsisThe principles of drug therapies are fundamental to medical practitioners in all branches; but are often difficult to get to grips with.Table of ContentsPreface v How to Use Your Textbook vi About the Companion Website ix Part 1 Basic Principles of Prescribing 1 1 Introduction: principles of good prescribing 2 2 Revision: pharmacokinetics 4 3 Using the British National Formulary 6 4 Taking a medication history 8 5 Reviewing current medicines 10 Part 2 Drug Selection 13 6 How to choose a drug 14 7 How to choose frequency 15 8 How to choose a dose 16 9 How to choose route of administration and formulation 18 10 How to choose duration of treatment, defi ne treatment objectives and measure outcomes 20 11 Assessing suitability of treatment regimens for patients 21 12 Worked example 1: Chapters 6–11 22 13 Worked example 2: Chapters 6–11 23 Part 3 Prescribing for Special Groups 25 14 Prescribing in liver disease 26 15 Prescribing in renal disease 28 16 Prescribing in children 30 17 Prescribing in the elderly 32 18 Prescribing in pregnancy and breast feeding 34 Part 4 Logistics of Prescribing 37 19 How to write a drug prescription 38 20 Communicating with patients about medicines 40 21 Therapeutic drug monitoring 42 22 Dealing with adverse drug reactions 44 23 Avoiding drug interactions (drugs, food and alternative medicines) 46 24 Avoiding prescribing errors 48 Part 5 Specific Drug Groups 51 25 Using drugs for the gastrointestinal system 52 26 Using drugs for the cardiovascular system I 54 27 Using drugs for the cardiovascular system II 56 28 Using drugs for the cardiovascular system III 58 29 Using drugs for the respiratory system 60 30 Using drugs for the neurological system I 62 31 Using drugs for the neurological system II 64 32 Using drugs for infection 66 33 Using drugs for the endocrine system I 68 34 Using drugs for the endocrine system II 70 35 How to use drugs for the musculoskeletal system 72 36 Using drugs in haematology and oncology 74 37 Using drugs in anaesthesia 76 38 An approach to common prescribing requests I 78 39 An approach to common prescribing requests II 80 Appendix Cross references to Prescribing Scenarios at a Glance 81 Index 82
£28.45
John Wiley & Sons Inc Green Techniques for Organic Synthesis and
Book SynopsisAn updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique's features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry.It is divided into 4 parts. The Table of ContentsList of Contributors xvii Foreword xxi Preface xxiii Part I General Topics in Green Chemistry 1 Green ChemistryMetrics 3Frank Roschangar and Juan Colberg 1.1 Business Case 3 1.2 Historical Context 3 1.3 Metrics, Awards, and Barriers 4 1.4 Metrics Unification Via Green Aspiration Level 9 1.5 Green Scorecard 12 1.6 Supply Chain 14 1.7 Outlook and Opportunities 15 References 17 Green Solvents 21Janet L. Scott and Helen F. Sneddon 2.1 Introduction 21 2.2 Solvent Selection Guides and Tools 23 2.3 Greener Molecular Solvents 24 2.4 Opportunities, Challenges, and Future Developments 34 References 34 Green Analytical Chemistry 43Paul Ferguson and Douglas Raynie 3.1 Introduction 43 3.2 Sample Preparation 47 3.3 Techniques and Methods 50 3.4 Process Analytical Technology 60 3.5 Biopharmaceutical Analysis 62 3.6 Conclusions 65 Acknowledgments 66 References 66 Green Engineering 71Christopher L. Kitchens and Lindsay Soh 4.1 Introduction: Green Engineering Misconceptions and Realizations 71 4.2 12 Principles of Green Engineering 72 4.3 Green Chemistry Metrics Applied to Engineering 73 4.4 Use of Green Solvents in the Chemical Industry 80 4.5 Presidential Green Chemistry Awards 86 4.6 Opportunities and Outlook 87 References 87 Greening of Consumer Cleaning Products 91David C. Long 5.1 History of Green Consumer Cleaning Products 91 5.2 Drivers for Greener Products 94 5.3 Development of Green Cleaning Criteria and Eco-Labeling 98 5.4 Development of Greener Ingredients for Cleaners 102 5.5 The Future of Green Cleaning 111 Acknowledgments 112 References 112 Innovation with Non-Covalent Derivatization 117John C.Warner and Emily Stoler 6.1 Introduction 117 6.2 NCD Overview 118 6.3 Pharmaceutical NCDs 121 6.4 Environmental and Green Chemistry Benefits 123 References 123 Part II Green Catalysts 131 Catalytic C-H Bond Cleavage for Heterocyclic Compounds 133Zhanxiang Liu and Yuhong Zhang 7.1 Introduction 133 7.2 Synthesis of Nitrogen Heterocycles 133 7.3 Synthesis of Oxygen-Containing Heterocycles 144 7.4 Synthesis of Sulfur-Containing Heterocycles 148 7.5 Medium-Sized Heterocyclic Compounds 150 7.6 Conclusion 152 References 152 Biocatalysis 161James Lalonde 8.1 Introduction 161 8.2 Enzymes for Biocatalysis 162 8.3 Advances in Enzyme Engineering and Directed Evolution 164 8.4 Biocatalytic Synthesis of Pharmaceuticals: Case Studies of Highly Efficient Pharmaceutical Syntheses 165 8.5 Summary and Future Outlook 178 References 180 Practical Asymmetric Organocatalysis 185Wen-Zhao Zhang, Samik Nanda, and Sanzhong Luo 9.1 Introduction 185 9.2 Aminocatalysis 185 9.3 Brønsted Acid Catalysis 191 9.4 Brønsted Base Catalysis 193 9.5 Hydrogen-Bonding Catalysis 197 9.6 Phase-Transfer Catalysis 202 9.7 Lewis Acid, Lewis Base, and N-Heterocyclic Carbene Catalysis 204 9.8 Large-Scale Reaction (>100-Gram Reaction) 207 9.9 Conclusion 209 References 209 Fluorous Catalysis 219L´aszl´o T. Mika and Istv´an T. Horv´ath 10.1 Introduction and the Principles of Fluorous Catalysis 219 10.2 Ligands for Fluorous Transition Metal Catalysts 224 10.3 Synthetic Application of Fluorous Catalysis 225 10.4 Fluorous Organocatalysis 256 10.5 Other Applications of Fluorous Catalysis 259 References 259 Solid-Supported Catalysis 269Sukanta Bhattacharyya and Basudeb Basu 11.1 Introduction 269 11.2 Immobilized Palladium Catalysts 270 11.3 Immobilized Rhodium Catalysts 276 11.4 Immobilized Ruthenium Catalysts 279 11.5 Other Immobilized Catalysts 284 11.6 Conclusions 286 References 287 Asymmetric Organocatalysis in Aqueous Media 291Kartick C. Bhowmick and Tanmoy Chanda 12.1 Introduction 291 12.2 Carbon-Carbon Bond-Formation Reactions 292 12.3 Reactions Other than C-C Bond Formation 313 12.4 Conclusion 314 References 314 Part III Green Synthetic Techniques 325 Solvent-Free Synthesis 327Kendra Leahy Denlinger and JamesMack 13.1 Introduction 327 13.2 Ball Milling 328 References 339 Ultrasonic Reactions 343Rodrigo Cella and H´elio A. Stefani 14.1 Introduction 343 14.2 How Does CavitationWork? 343 14.3 Aldol/Condensation Reactions 345 14.4 1,4-Addition 351 14.5 Heterocycles Synthesis 353 14.6 Coupling Reactions 356 14.7 Wittig Reaction 361 14.8 Diels-Alder Reaction 362 14.9 Miscellaneous 365 14.10 Conclusions 366 References 366 Photochemical Synthesis 373Stefano Protti,Maurizio Fagnoni, and Angelo Albini 15.1 Introduction 373 15.2 Synthesis and Rearrangement of Open-Chain Compounds 376 15.3 Synthesis of Three- and Four-Membered Rings 382 15.4 Synthesis of Five-, Six- (and Larger)-Membered Rings 391 15.5 Oxygenation and Oxidation 398 15.6 Conclusions 400 Acknowledgments 401 References 401 Pot Economy Synthesis 407Wenbin Yi, Xin Zeng, and Song Gao 16.1 Introduction 407 16.2 Multicomponent Reactions 407 16.3 One-Pot and Multi-Step Reactions 415 16.4 One-Pot Asymmetric Synthesis 424 16.5 Outlook 434 References 434 Microwave-Assisted Organic Synthesis: Overview of Recent Applications 441Nandini Sharma, Upendra K. Sharma, and Erik V. Van der Eycken 17.1 Introduction 441 17.2 C-H Functionalization 449 17.3 Insertion Reactions 452 17.4 Reduction 453 17.5 Synthesis of Peptides and Related Fine Chemicals 455 17.6 Newer Developments 459 17.7 Summary 461 References 461 Solid-Supported Synthesis 469Indrajeet J. Barve and Chung-Ming Sun Abbreviations 469 18.1 Introduction 471 18.2 Techniques of Solid-Phase Supported Synthesis 472 18.3 Solid-Phase Supported Heterocyclic Chemistry 476 18.4 Solid-Supported Synthesis of Natural Products 486 18.5 Solid-Supported Organometallic Chemistry 491 18.6 Solid-Phase Synthesis of Peptides 493 18.7 Solid-Phase Supported Stereoselective Synthesis 494 18.8 Interdisciplinary Solid-Supported Synthesis 499 References 505 Light Fluorous Synthesis 509Wei Zhang 19.1 Introduction 509 19.2 “Heavy” Versus “Light” Fluorous Chemistry 509 19.3 The Green Chemistry Aspects of Fluorous Synthesis 510 19.4 Fluorous Techniques for Discovery Chemistry 511 19.5 Conclusions 533 References 533 Part IV Green Techniques and Strategies in the Pharmaceutical Industry 539 Ionic Liquids in Pharmaceutical Industry 541Julia L. Shamshina, Paula Berton, HuiWang, Xiaosi Zhou, Gabriela Gurau, and Robin D. Rogers Abbreviations 541 20.1 Introduction 543 20.2 Finding the Right Role for ILs in the Pharmaceutical Industry 544 20.3 Conclusions and Prospects 567 References 568 Green Technologies and Approaches in theManufacture of Biologics 579Sa V. Ho and Kristi L. Budzinski 21.1 Introduction 579 21.2 Characteristics of Biologics 580 21.3 Manufacture of Therapeutic Biologics 581 21.4 Environmental Metrics Development and Impact Analysis 587 21.5 Some Future Directions 592 21.6 Conclusions 594 Acknowledgments 594 References 594 Benchmarking Green Chemistry Adoption by “Big Pharma”and Generics Manufacturers 601Vesela R. Veleva and BerkeleyW. Cue 22.1 Introduction 601 22.2 Literature Review 602 22.3 Pharmaceutical Industry Overview and Green Chemistry Drivers 604 22.4 Benchmarking Industry Adoption of Green Chemistry 607 22.5 Results and Discussion 610 22.6 Conclusion 616 References 616 Green Process Chemistry in the Pharmaceutical Industry: Case Studies Update 621Joseph M. Fortunak, Ji Zhang, Frederick E. Nytko III, and Tiffany N. Ellison 23.1 Introduction 621 23.2 Pharmaceutical Patents Driving Innovation 622 23.3 A Caution About Drug Manufacturing Costs 623 23.4 Process Evolution by Multiple Route Discovery Efforts—Dolutegravir 624 23.5 The Impact of Competition on Process Evolution—Tenofovir Disoproxil Fumarate 628 23.6 Simeprevir (Olysio/Sovriad) and Analogues: Chiral Phase-Transfer Catalyst-Promoted Optical Alpha-Amino Acid Synthesis: A Metal-free Process 633 23.7 Vaniprevir (MK 7009), Simeprevir (TMC435), and Danoprevir: Ring-Closing Metathesis (RCM) for Macrocyclic Lactam Synthesis: Now a Commercial Reality 635 23.8 Daclatasvir (BMS-790052, Daklinza), and Ledipasvir (GS-5885): Palladium Catalyzed Cross-Coupling for Greening a Process 638 23.9 Sitagliptin (Januvia) and Ponatinib (Iclusig): Greening the Process by Telescoping Multiple Steps Together 639 23.10 Febuxostat (Uloric): Greening the Process via Metal Catalyzed C-H Activation: A Prospect 641 23.11 Conclusions 644 References 644 Greener Pharmaceutical Science Through Collaboration: The ACS GCI Pharmaceutical Roundtable 649Julie B. Manley andMichael E. Kopach 24.1 Introduction 649 24.2 Establishing Pre-Competitive Collaborations 650 24.3 Informing and Influencing the Research Agenda 654 24.4 Developing Tools 661 24.5 Educating Leaders 666 24.6 Collaborating Globally 668 24.7 Future Opportunities 669 24.8 Success Factors 671 References 673 Index 675
£143.06
John Wiley and Sons Ltd Fundamentals of Pharmacology
Book SynopsisTable of ContentsChapter 1 Introduction to pharmacology 1Ian Peate Chapter 2 How to use pharmaceutical and prescribing reference guides 15Claire Pryor and Annette Hand Chapter 3 Legal and ethical issues 33Claire Leader, Emma Senior and Deborah Flynn Chapter 4 Medicines management and the role of the healthcare provider 49Annette Hand and Carol Wills Chapter 5 Pharmacodynamics and pharmacokinetics 69Barry Hill and Jaden Allan Chapter 6 Drug formulations 91Hayley Underdown and Nicola Clipperton Chapter 7 Adverse drug reaction 111Laura Park and Michelle Mitchell Chapter 8 Analgesics 127Claire Ford and Matthew Robertson Chapter 9 Antibacterials 153Deborah Flynn Chapter 10 Medications used in the cardiovascular system 187Jan Guerin and Cecilia Mihaila Chapter 11 Medications and the renal system 225Sadie Diamond‐Fox and Alexandra Gatehouse Chapter 12 Medications and diabetes mellitus 285Anne Phillips Chapter 13 Medications and the respiratory system 313Sadie Diamond‐Fox and Alexandra Gatehouse Chapter 14 Medications and the gastrointestinal system 369David Waters and Ian Naldrett Chapter 15 Medications used in cancer 389Elaine Walls and Leah Rosengarten Chapter 16 Medications and the nervous system 415Julie Derbyshire Chapter 17 Medications used in mental health 437Laura Stavert Chapter 18 Immunisations 465Aby Mitchell Normal Values 491 Answers 495 Index 49
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John Wiley and Sons Ltd Clinical Pharmacology and Therapeutics
Book SynopsisTable of ContentsPreface vi Contributors vii Part 1 Principles of clinical pharmacology 1 Pharmacodynamics and pharmacokinetics 3 2 Clinical trials and drug development 29 3 Pharmacoeconomics: the economic evaluation of new drugs 35 4 Practical prescribing 42 Part 2 Aspects of prescribing 5 Gastrointestinal system 51 6 Cardiovascular system: Management of coronary artery disease and its complications 63 7 Respiratory system 102 8 Nervous system 113 9 Infection 142 10 Drugs and endocrine disease 175 11 Genitourinary system 196 12 Malignant disease 211 13 Drugs and the blood 221 14 Musculoskeletal system 236 15 Immunopharmacology 242 16 Travel medicine 255 17 Analgesia and anaesthesia 266 18 Poisoning and drug overdose 281 Index 295
£42.02
Taylor & Francis Ltd Breastfeeding and Medication
Book SynopsisSadly, women often feel they have no alternative but to give up breastfeeding, having been prescribed or purchased medication. In many cases, however, this is unnecessary. This book outlines the evidence base for the use of medication during breastfeeding. Breastfeeding and Medication presents a comprehensive A to Z guide to the most frequently prescribed drugs and their safety for breastfeeding mothers. Evaluating the evidence for interventions and using a simple format for quickly identifying medications that are safe or unsafe to use, it also highlights those drugs where there is inconclusive evidence. Additional contextual information makes this the most complete text for those practitioners who support and treat breastfeeding women. It: provides an overview of the anatomy and physiology of the breast together with hormonal influences to better understand how complications, such as mastitis, arise and inform the approach to their treatmeTable of ContentsPart I Introduction Chapter 1 Breastfeeding in context Chapter 2 How does breastfeeding work? Chapter 3 Constituents of breastmilk and formula milk Chapter 4 Understanding the importance of breastmilk Chapter 5 Treating conditions related to breastfeeding Chapter 6 Decision-making on the safety of drugs in breastmilk Chapter 7 Professional responsibility and counselling Chapter 8 Chronic diseases and medication in the breastfeeding mother Part II Chapter 9 Information on level of drugs into breastmilk References
£37.99
