Infectious and contagious diseases Books

Book SynopsisGround-breaking, evidence-based book asks how many lives were lost because of Chinas negligence about lab-leaked SARS-CoV-2. In a disturbing reconstruction of events by two of the most reputable scientists in the world, a new book reveals for the first time how Chinese authorities and elite Wuhan scientists knew about SARS-CoV-2s menacing biological features from the start but remain silent to this day. In The Origin of the Virus (Clinical Press) Dr Steven Quay and Prof Angus Dalgleish, working with Italian reporter Paolo Barnard, show how China engaged in lies, omissions and obfuscations to cover up the laboratory origin of the virus. Had they immediately alerted the international community and policymakers of the extremely pathogenic molecular machinery present in SARS-CoV-2's genome, very large numbers of lives may have been spared, argue Quay, Dalgleish and Barnard. The authors provide a shocking account of the extreme experiments that led to the outbreak of the worst pandemic since the 1918 Spanish influenza. They broaden the censure to explain why some American and British scientists thwarted a proper investigation of the origin of COVID-19. Despite its impeccable scientific grounding the book is both a readable and gripping account that, for the first time, allows the public to partake in what lies at the heart of the many scandals surrounding the birth of the most deadly virus in modern times.Trade ReviewThe beauty of this book lies in its totally convincing narrative in a concise and entirely readable form. As a lay person with regard to medical matters I found the introductory chapter by the man who put the project together, Paolo Barnard, both fascinating and compelling, reading like a particularly enthralling story. Then the science kicks in with some hard academic research from Professor Dalgleish examining the genome of the virus and the peculiar nature of the spike proteins put there by Gain of Function studies of concern. Although impeccable in its reasoning the matters were explained in terms that are fully understandable. Then follows a nice cheeky chapter from doctor/scientist Steven Quay at the end of the book which lays out in a wonderfully logical manner how a bookie might view the odds of either zoonosis or lab-leak as the origin of the virus causing the Covid-19 pandemic .... an analysis supported by something called Bayesian statistics. I have read other books on the same matter but in my opinion this is the best .... the rival tomes are too large, filled out by journalese or just plain wrong. Once you realise that the virus has been made in a unique way such that it can attack almost any cell in the human body you begin to understand the importance of preventative measures and also become angry that the dangerous Gain of Function studies are continuing and worried that unless they are stopped the next pandemic of a novel virus will be even worse. Anthony Lloyd, primary schoolteacher and musician in Bristol, England (Review in Caduceus)

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Book SynopsisSince the onset of the coronavirus disease 2019 (COVID-19) pandemic in early 2020, many individuals infected with the virus that causes COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have continued to experience lingering symptoms for months or even years following infection. Some symptoms can affect a person's ability to work or attend school for an extended period of time. Consequently, in 2022, the Social Security Administration requested that the National Academies convene a committee of relevant experts to investigate and provide an overview of the current status of diagnosis, treatment, and prognosis of long-term health effects related to Long COVID. This report presents the committee conclusions. Table of ContentsFront MatterSummary1 Introduction2 Diagnosis of SARS-CoV-2 Infection3 Selected Long-Term Health Effects Stemming from COVID-19 and Functional Implications4 Global Functioning in Long COVID5 Chronic Conditions Similar to Long COVID6 Overall ConclusionsAppendix A: Public Meeting AgendasAppendix B: Literature Search StrategiesAppendix C: Biographical Sketches of Committee Members

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Book SynopsisA real-life thriller about a nation in crisis, and the controversial decisions its leaders made during the Covid-19 pandemic. First, the government instituted no restrictions. Then, it didn’t order the wearing of face masks. While the rest of the world looked on with incredulity, condemnation, admiration, and even envy, a small country in Northern Europe stood alone. As Covid-19 spread across the globe rapidly, the world shut down. But Sweden remained open. The Swedish Covid-19 strategy was alternately lauded and held up as a cautionary tale by international governments and journalists alike — with all eyes on what has been dubbed ‘The Swedish Experiment’. But what made Sweden take such a different path? In The Herd, journalist Johan Anderberg narrates the improbable story of a small nation that took a startlingly different approach to fighting the virus, guiding the reader through the history of epidemiology and the ticking-clock decisions that pandemic decision-makers were faced with on a daily basis.Trade Review‘One of Sweden’s most popular books about its pandemic.’ -- Derek Scally * The Irish Times *‘In his fine book The Herd, the Swedish journalist Johan Anderberg has chronicled the development of the Swedish policy and how tough it was for its architect, Anders Tegnell, to stay the course as country after country was stampeded into compulsory and comprehensive lockdowns.’ -- Matt Ridley * The Telegraph *‘The Herd is a thrilling read about tight-knit groups of microbiologists and epidemiologists, old grudges, new alliances, and fiery emails … Anderberg is ambitious, knowledgeable, and fearless.’ -- Dagens Nyheter‘The Herd is exemplary journalism of the kind that comes close to the truth through skilled craftsmanship. Anderberg portrays the events in the right order. He relies on relevant facts. He puts the last year in a historical context. He examines without preconceived opinions … Anderberg’s book is like a Corona commission in its own right and a beautiful example of the important role journalism plays in the service of the truth.’ * Barometern *‘Reading Johan Anderberg’s book is not just a way to get perspective and background, detailed descriptions of how the Swedish strategy was formed and what it led to. It is also a way to be released from the debate, both in social and other media. It is extremely cooling. The Herd is no debate book; it is a nuanced report from an incredibly strange time. So strange you need help finding the words to talk about it.’ * Aftonbladet *‘Journalist Johan Anderberg makes a brave effort to tell the story about how Sweden chose its path through the pandemic … Anderberg’s narrative has an effortless ease that manifests itself once the writer has a clear overview, and truly masters his subject without getting sidetracked and stuck on details.’ * Sydsvenskan *‘Anderberg masters to perfection the societal reportage that closely examines the authorities, effortlessly taking us into the meeting rooms and email inboxes where the Swedish Corona strategy took shape. With efficiency and humour, he visualises his protagonists … In a climate where media personalities — myself included — often acted as supporters, critics, and hobby epidemiologists, Anderberg has instead buried himself in facts and tried to paint the overall picture … Questions remain after having finished reading The Herd, but this in no way takes away the honour of having accomplished this impressive pioneering work with such energy and wit from Johan Anderberg. The Herd is sure to greatly impact the debate that we’ve only seen the nascent beginnings of so far.’ * Expressen *‘When the world went into lockdown, Sweden went its own way, and this is the fascinating inside story – superb long journalism.’ * The Sydney Morning Herald *‘A gripping history of Sweden’s Covid response. The people and the power struggles — and how science beat panic.’ -- Fraser Nelson * The Spectator *‘[C]onvincing debut from Swedish journalist Anderberg … Anderberg’s account is peppered with details that add depth to the colourful cast … This is a fascinating addition to the growing body of work on Covid-19.’ * Publishers Weekly *‘A gripping analysis of the Swedish response, which examines how tensions between science, policy and politics heightened as the virus held on. If any book were capable of turning scientific debate into a thriller, this one does so; and for the armchair experts on Covid-19 that many of us have become, it is a must-read.’ -- Frieda Klotz * Sunday Independent *

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Book SynopsisSince the start of the 21st century, the world has been experiencing numerous infectious disease outbreaks, with little time to breath between events. This fictional novel takes place in various countries across the globe that are dealing with large infectious disease outbreaks due to viruses causing yellow fever, Zika,, Ebola and COVID-19. David Ferguson, in the World Health Organization's Emergency Preparedness Division, attempts to deal with these outbreaks, but must overcome numerous logistical, political and ethical roadblocks while becoming involved in a romantic relationship with Aceline Durand, who works for Medecins Sans Frontiers.

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Book SynopsisThe book studies the impact of COVID-19 on the Chinese economy and the country's response to policies. It examines various aspects of national macroeconomic operations, industrial shocks, changes in financial markets, regional economic order, public governance challenges. It also analyzes changes in the world economy while integrating economic, financial, industrial, and environmental disciplines.At the macro level, the book emphasizes counter-cyclical responses, with an emphasis on comprehensive measures and precise efforts. It highlights differentiated development strategies for industries and promotes structural adjustment and supply-side reform. At the micro-level, the book emphasizes enterprises' resumption of work and production and supply chain management. The book promotes the concept of integration, stressing that China's economy was and is sufficiently resilient and the importance of maintaining and improving public confidence. At the same time, it attaches importance to prescribing the correct remedies for shortcomings, strengthening weaknesses, confronting the obstacles and difficulties in economic development, and restoring social order. The studies are not restricted to the facts but also focus on transforming and upgrading a modernized socialist economy and governance in the long term.

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Book SynopsisJonathan Kennedy teaches global public health at Queen Mary University of London. He has a PhD in sociology from the University of Cambridge. His interdisciplinary research has been published in leading medical, public health, sociology and history journals, and he has written for newspapers including the Guardian and El Pais. Pathogenesis is his first book.

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Book Synopsis'Manaugh and Twilley shed illuminating light on a phenomenon that seems utterly of the present moment.' Financial Times’ Best Books of the Year'Startlingly timely, authoritatively researched, and electrifyingly written.' Steve Silberman, author of NeuroTribes: The Legacy of Autism and the Future of NeurodiversityQuarantine has shaped our world, yet it remains both feared and misunderstood. It is our most powerful response to uncertainty, but it operates through an assumption of guilt: in quarantine, we are considered infectious until proven safe. An unusually poetic metaphor for moral and mythic ills, quarantine means waiting to see if something hidden inside of us will be revealed. Until Proven Safe tracks the history and future of quarantine around the globe, chasing the story of emergency isolation through time and space – from the crumbling lazarettos of the Mediterranean to the hallways of the CDC, to the corporate giants hoping to disrupt the widespread quarantine imposed by Covid-19 before the next pandemic hits through surveillance and algorithmic prediction.Yet quarantine is more than just a medical tool: Geoff Manaugh and Nicola Twilley drop deep into the Earth to tour a nuclear-waste isolation facility beneath the New Mexican desert, strip down to nothing but protective Tyvek suits to see plants stricken with a disease that threatens the world’s wheat supply, and meet NASA’s Planetary Protection Officer tasked with saving the Earth from extraterrestrial infections. The result is part travelogue, part intellectual history – a book as compelling as it is definitive, and one that could not be more urgent or timely.Trade ReviewReads like a global safari of humanity’s best-laid plans being never quite enough . . . [Manaugh and Twilley] are well-placed to tell the tale, weaving the spatial, social and scientific facets of medical isolation into an entertaining adventure. -- Oliver Wainwright * Guardian *A timely intellectual history of quarantine . . . As Manaugh and Twilley write, quarantine is enforced in cases of potential infection, of possible risk, and ­therefore admits a degree of uncertainty. One of the striking continuities in their history is how this uncertainty has been exploited to deepen gendered and racialised inequalities. -- Erin Maglaque * New Statesman *A compelling case that we must continue to refine the use of quarantine, balancing the needs of public health with those of human rights. * New Yorker *Until Proven Safe is not all doom and gloom, though: there are plenty of QI-style facts in this wide-ranging and colourful survey. -- Christopher Hart * Sunday Times *Until Proven Safe, by Geoff Manaugh and Nicola Twilley, dives into the crudely effective and widely abused strategy of quarantine, the separation of those feared to be sick from those deemed healthy. -- Ian Sample * Guardian Best Science Books of the Year *Brainy but accessible -- Mark Honigsbaum * Observer *Manaugh and Twilley shed illuminating light on a phenomenon that seems utterly of the present moment. * Financial Times' Best Books of the Year *[Manaugh and Twilley] bring an impressively wide range of interests to bear on a subject that involves not only infectious disease but also - in their ambitious yet seamless narration - politics, agriculture, surveillance and even outer space. -- Jennifer Szalai * New York Times Book Review *What makes [Until Proven Safe] compelling, besides [Manaugh and Twilley’s] extensive experience as journalists, is the depth of their research coupled with a firm conviction that quarantine, a mighty yet dangerous weapon, must be used ‘more wisely in the future’ . . . This is an exceptionally powerful book -- A. Roger Ekirch * Wall Street Journal *Until Proven Safe is uncanny in its prescience . . . Twilley and Manaugh see things that others don’t. Their insatiable curiosity reveals itself through all of their endeavors -- Allison Arieff * San Francisco Chronicle *Manaugh’s and Twilley’s extensive history of a concept we might otherwise take for granted is actually the perfect postpandemic read - an imaginative, layperson-friendly way to make sense of and contextualize what we just lived through. -- Arianna Rebolini * BuzzFeed *Quarantine provides a buffer and a delay, offering space and time, between the known (healthy folks) and the dangerous (potentially contagious people). Its complicated nature is adeptly explored, including ethical concerns, legal and moral questions, and enforcement challenges . . . Fascinating reading. -- Tony Miksanek * Booklist *A riveting and timely look at how humanity has protected itself by isolating segments of its populations. . . Manaugh and Twilley cull their research into a concise and logical series of recommendations for future public health crises, grounded in a deep appreciation of the human impact of quarantining. * Publishers Weekly *Captivating . . . Manaugh and Twilley meld a global view of a timely subject with vividly detailed accounts . . . But a larger charm of this smart book lies in their ability to bring potentially dry topics to life . . . An infectiously appealing overview of efforts to contain the potentially infectious. * Kirkus Reviews *Until Proven Safe is the book of our historical moment - a provocative meditation on how society uses quarantine to define the boundaries of self and other when faced with the terrifying unknown. Startlingly timely, authoritatively researched, and electrifyingly written. -- Steve Silberman, author of NeuroTribes: The Legacy of Autism and the Future of NeurodiversityUntil Proven Safe combines history, geography, epidemiology, and the ethics of space exploration – how can this be – Because, as the authors explain in a very entertaining and wide-ranging way, quarantine, ironically enough, crosses borders of space and time to make a complex knot of stories. Timely, eye-opening, provocative – you will see the world differently after reading it. -- Kim Stanley Robinson, author of Ministry for the FutureWhat does it mean to isolate threats: people carrying diseases; the microbes, themselves; radioactive materials? For centuries the primary tool of isolation has been quarantine, and in this globe-trotting tale of history and today’s COVID-19 crisis, Geoff Manaugh and Nicola Twilley offer answers that will make your jaw drop. Nothing about "quarantine" is as simple or straight-forward as you think. -- Laurie Garrett, author of The Coming Plague: Newly Emerging Diseases in a World out of BalanceAn engrossing study of the ways in which quarantines have changed social, emotional, and political life over hundreds of years, and a fascinating exploration of the perennial roles of fear, conspiracy theories, greed, and prejudice, to which we now add the threat of permanent digital surveillance in the name of public health. Perfect for our time and guidance for the future. -- Ellen Ullman, author of Close to the Machine and Life in CodeAs Twilley and Manaugh reveal in this timely but timeless, ambitious and flawlessly executed account, quarantines have shaped our history . . . The struggle to protect ourselves from invisible and deadly contagions is waged daily and largely out of sight - along borders and spore superhighways, in biosecure piggeries and nuclear waste facilities a half-mile underground. Quarantine: boring to live through, unbelievably interesting to read about. -- Mary Roach, author of Stiff and GruntStrap on your plague beaks and round up the loose women! In this intrepid, occasionally creepy jaunt through seven centuries of disease control, Twilley and Manaugh prove that the past is never dead; it’s just in quarantine. -- Alexis Coe, author of You Never Forget Your First: A Biography of George Washington

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Book SynopsisTrade Review"A Choice Outstanding Academic Title of the Year""An entry-level introduction to virology that fascinated me"---Leon Vlieger, Inquisitive Biologist"This book offers an excellent overview of the main tenets of viral biology, designed to help readers better understand why viruses cause infection while also highlighting how our environment could not function properly without them."---C. Kale, Choice"Throughout her infectiously enthusiastic, irresistibly illustrated analysis, [Roossinck] emphasizes viral complexity.`"---Andrew Robinson, Nature"[This book] will surely inspire future generations of scientists."---William P. Hanage, The Quarterly Review of Biology

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Book SynopsisFor over half a century, the CDC Yellow Book has been a trusted resource, providing international travelers and clinicians with expert guidance for safe and healthy travel abroad. Along with disease-specific prevention and treatment recommendations, this comprehensive reference text provides readers with the background and context needed to understand and address health threats associated with all types of international travel.FEATURED IN THIS EDITION: Precautions for international travelers during the coronavirus disease 2019 (COVID-19) pandemic, including links to updated information on related CDC and US government websites Updates on practicing travel medicine in a virtual environment New standalone vaccine tables for bacterial and viral diseases with links to the relevant Advisory Committee on Immunization Practices and US FDA websites Safe international travel with pets and service animals Advice for obtaining healthcare abroad including guidance on different types of travel insurance Guidelines for self-treating common travel conditions including altitude illness, jet lag, motion sickness, and travelers'' diarrhea Detailed maps showing the distribution of travel-associated infections and diseases, including dengue and meningococcal meningitis Country-specific mosquito avoidance, yellow fever vaccine, and malaria prevention recommendations Food and drink precautions, plus updated water-disinfection techniques Expanded content on safe international travel for specific groups including: LGBTQ+ individuals, highly allergic travelers, travelers with substance use issues, and medical tourists Specialized recommendations for non-leisure travelers, study abroad, work-related travel, and travel to mass gatherings Health insights for 14 popular destinations and itineraries in Africa and the Middle East, the Americas and the Caribbean, and Asia Considerations for newly arrived adoptees, immigrants, and refugeesTrade ReviewA beloved travel must-have for the intrepid wanderer." -Publishers WeeklyA truly excellent and comprehensive resource." -Journal of Hospital InfectionThis is a very well-written book that provides a great explanation of the core principles of travel medicine. This [2020] edition includes updated recommendations on some of the vaccines, such as the yellow fever vaccine. An understanding of the concepts in this book serves the needs of clinicians who aim to conquer the outbreaks of infectious diseases associated with travel. (Weighted Numerical Score: 100 - 5 Stars!) * Manasa Velagapudi, Doodys *This is the gold-standard in the field of travel medicine due to its enormous scope, expertise, and ease of use. * Kenneth Schaefle, MD, Albert Einstein College of Medicine, Doody's Book Review *Table of ContentsList of Maps, by topic CDC Contributors External Contributors Acknowledgments Preface Dedication 1 Introduction Disease Patterns in Travelers ...perspectives: Why Guidelines Differ Maps & Travel Medicine Improving the Quality of Travel Medicine through Education & Training 2 Preparing International Travelers The Pretravel Consultation ...perspectives: Travelers' Perception of Risk Vaccination & Immunoprophylaxis-General Principles Interactions Between Travel Vaccines & Drugs Yellow Fever Vaccine & Malaria Prevention Information, by Country Travelers' Diarrhea ...perspectives: Antibiotics in Travelers' Diarrhea-Balancing Benefit & Risk Food & Water Precautions Water Disinfection Travel Health Kits Last-Minute Travelers Mental Health LGBTQ+ Travelers Complementary & Integrative Health Approaches to Travel Wellness Prioritizing Care for Resource-Limited Travelers Telemedicine ...perspectives: Risk Management Issues in Travel Medicine 3 Travelers with Additional Considerations Immunocompromised Travelers Travelers with Disabilities Travelers with Chronic Illnesses Highly Allergic Travelers Substance Use & Substance Use Disorders 4 Environmental Hazards & Risks Sun Exposure Extremes of Temperature Air Quality & Ionizing Radiation Scuba Diving: Decompression Illness & Other Dive-Related Injuries High Elevation Travel & Altitude Illness Mosquitoes, Ticks & Other Arthropods Zoonotic Exposures: Bites, Stings, Scratches & Other Hazards Zoonoses-The One Health Approach Bringing Animals & Animal Products into the United States Food Poisoning from Marine Toxins Safety & Security Overseas Injury & Trauma Death During Travel 5 Travel-Associated Infections & Diseases BACTERIAL Vaccine-Preventable Diseases: Bacterial Anthrax Bartonella Infections Brucellosis Campylobacteriosis Cholera Diphtheria Escherichia coli, Diarrheagenic Helicobacter pylori Legionnaires' Disease & Pontiac Fever Leptospirosis Lyme Disease Melioidosis Meningococcal Disease Pertussis / Whooping Cough Plague Pneumococcal Disease Q Fever Rickettsial Diseases Salmonellosis, Nontyphoidal Shigellosis Tetanus Tuberculosis ...perspectives: Testing Travelers for Mycobacterium tuberculosis Infection Typhoid & Paratyphoid Fever Yersiniosis VIRAL Vaccine-Preventable Diseases: Viral B Virus Chikungunya COVID-19 Dengue Hand, Foot & Mouth Disease Henipavirus Infections Hepatitis A Hepatitis B Hepatitis C Hepatitis E Human Immunodeficiency Virus / HIV Influenza Japanese Encephalitis Middle East Respiratory Syndrome / MERS Mumps Norovirus Poliomyelitis Rabies ...perspectives: Rabies Immunization Rubella Rubeola / Measles Smallpox & Other Orthopoxvirus-Associated Infections Tick-Borne Encephalitis Varicella / Chickenpox Viral Hemorrhagic Fevers Yellow Fever Zika PARASITIC Amebiasis Angiostrongyliasis Cryptosporidiosis Cutaneous Larva Migrans Cyclosporiasis Cysticercosis Echinococcosis Enterobiasis / Pinworm Filariasis, Lymphatic Flukes, Liver Flukes, Lung Giardiasis Helminths, Soil-Transmitted Leishmaniasis, Cutaneous Leishmaniasis, Visceral Malaria Onchocerciasis / River Blindness Sarcocystosis Scabies Schistosomiasis Strongyloidiasis Taeniasis Toxoplasmosis Trypanosomiasis, African Trypanosomiasis, American / Chagas Disease FUNGAL Coccidioidomycosis / Valley Fever Histoplasmosis 6 Health Care Abroad Travel Insurance, Travel Health Insurance & Medical Evacuation Insurance Obtaining Health Care Abroad ...perspectives: Avoiding Poorly Regulated Medicines & Medical Products during Travel Medical Tourism 7 Family Travel Pregnant Travelers Travel & Breastfeeding Traveling Safely with Infants & Children Vaccine Recommendations for Infants & Children International Adoption Traveling with Pets & Service Animals 8 Travel by Air, Land & Sea Air Travel ...perspectives: Responding to Medical Emergencies when Flying Deep Vein Thrombosis & Pulmonary Embolism Jet Lag Road & Traffic Safety Cruise Ship Travel Motion Sickness Airplanes & Cruise Ships: Illness & Death Reporting & Public Health Interventions 9 Travel for Work & Other Reasons The International Business Traveler Advice for Aircrew ...perspectives: People Who Fly for a Living-Health Myths & Realities Health Care Workers, Including Public Health Researchers & Medical Laboratorians Humanitarian Aid Workers United States Military Deployments Long-Term Travelers & Expatriates Study Abroad & Other International Student Travel Visiting Friends & Relatives: VFR Travel Mass Gatherings Adventure Travel Sex & Travel 10 Popular Itineraries The Rationale for Popular Itineraries AFRICA & THE MIDDLE EAST African Safaris Saudi Arabia: Hajj & Umrah Pilgrimages South Africa Tanzania & Zanzibar THE AMERICAS & THE CARIBBEAN Brazil Dominican Republic Haiti Mexico Peru ASIA Burma (Myanmar) China India Nepal Thailand 11 Posttravel Evaluation General Approach to the Returned Traveler Rapid Diagnostic Tests for Infectious Diseases ...perspectives: Screening Asymptomatic Returned Travelers Fever in the Returned Traveler Antimicrobial Resistance Respiratory Infections Persistent Diarrhea in Returned Travelers Dermatological Conditions ...perspectives: Delusional Parasitosis Sexually Transmitted Infections Newly Arrived Immigrants, Refugees & Other Migrants

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Book SynopsisFully revised for its third edition, the Oxford Handbook of Expedition and Wilderness Medicine continues to be the essential resource for all expedition medics and well-informed travellers, as well as nurses, paramedics, medical students, and other expedition members travelling in remote, wilderness areas of the world. Now containing more guidance about caving medicine, the third edition includes revised and additional illustrations and essential maps of the spread of diseases. Clear and concise, readers can rely on this handbook to provide the key knowledge and practical advice they need. It enables efficient preparation and planning before the journey, advises on camp logistics, risk management, and medical problems during the expedition, as well as highlighting rare but important risks to those visiting remote areas. Focusing on preventative measures, it also contains chapters dealing with crisis management, emergency care, and evacuation from challenging environments, with guidance about the obligations of a clinician joining an expedition, ethical approaches to such work, and medicine in various extreme environments. This edition will give you the confidence and skills you need to travel to any extreme or remote environment. Incorporating the combined knowledge and experience of a team of experienced clinicians and expeditioners, this is a practical, easy-to-use guide to all aspects of expedition and wilderness medicine.Table of Contents1: Expedition medicine 2: Preparations 3: Caring for people in the field 4: Ethics and responsibilities 5: Crisis management 6: Emergencies: diagnosis 7: Emergencies: trauma 8: Emergencies: collapse and serious illness 9: Treatment: skin 10: Treatment: head and neck 11: Treatment: dental 12: Treatment: chest 13: Treatment: abdomen 14: Treatment: limbs and back 15: Treatment: infectious diseases 16: Psychological and psychiatric problems 17: Risks from animals 18: Plants and fungi 19: Anaesthesia in remote locations 20: Cold climates 21: Mountains and high altitude 22: Inland and coastal waters 23: Offshore 24: Underwater 25: Hot, dry environments: deserts 26: Hot, humid environments: tropical forest 27: Caving 28: Medical kits

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Book SynopsisVery Short Introductions: Brilliant, Sharp, Inspiring Throughout history plague has been the cause of many major catastrophes. It was responsible for the ''Plague of Justinian'' in 542, the Black Death of 1348, and the Great Plague of London in 1665, as well as for devastating epidemics in China and India between the 1890s and 1920s. In the 21st century Coronavirus pandemics have served as a powerful reminder that we have not escaped the global impact of epidemic diseases. In this Very Short Introduction, Paul Slack takes a global approach to explore the historical and social impact of plague over the centuries, looking at the ways in which it has been interpreted, and the powerful images it has left behind in art and literature. Examining what plague meant for those who suffered from it, and how governments began to fight against it, he demonstrates the impact plague has had on modern notions of public health, and how it has shaped our history. This new edition also includes evidence on the nature of plague taken from recent discoveries in ancient DNA as well as new research on plague in the Middle East. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.Trade ReviewReview from previous edition Slack takes a thematic approach to the global and comparative history of plague that provides a wonderful survey for the newcomer to the topic, while still providing food for thought to readers already well versed in the literature. * Patrick Wallis, LPS *This book is not a textbook on Pasteurella pestis. Rather, using the disease it causes as a link, the text has the potential to attract the interest and attention of a wide range of readers, encompassing historical, social, geographical and economic factors and the role they played in changing European and wider social development. In these days of internet access, soundbites and the decline of text on paper, this book presents an excellent opportunity for those who wish for an absorbing and educational narrative, contained within an extremely portable package and with no risk of the battery losing its charge at an inconvenient moment. * The Bulletin of The Royal College of Pathologists, April 2013 *Table of ContentsAcknowledgements List of Illustrations Introduction 1: Plague: what's in a name?? 2: Pandemics and epidemics 3: Big impacts: the Black Death 4: Private horrors 5: Public health 6: Enduring images 7: The lessons of histories References Further Reading Index

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Book SynopsisParasitic infections remain a significant cause of morbidity and mortality in the world today. Often endemic in developing countries many parasitic diseases are neglected in terms of research funding and much remains to be understood about parasites and the interactions they have with the immune system.Table of ContentsList of Contributors xiii Introduction: Immunoparasitology: The Making of a Modern Immunological science 1 Alan Sher Section 1 1 Notes on the Immune System 15 Tracey J. Lamb 1.1 The immune system 15 1.2 Innate immune processes 17 1.3 The complement cascade 19 1.4 Innate recognition 20 1.5 Pattern recognition receptors 21 1.6 Innate immune cells 23 1.7 Communication in the immune system 31 1.8 Adaptive immunity 31 1.9 The role of theMHC in the immune response 34 1.10 T cell activation and cellular-mediated immunity 36 1.11 B cells and the humoral response 43 1.12 Cell trafficking around the body 49 1.13 Cellular immune effector mechanisms 50 1.14 Hypersensitivity reactions 52 References for further reading 54 Section 2 2 Introduction to Protozoan Infections 61 David B. Guiliano and Tracey J. Lamb 2.1 The protozoa 61 2.2 Amoebozoa 62 2.3 Excavata 67 2.4 Harosa 75 2.5 Protozoa that are now fungi 81 2.6 Taxonomy and the evolution of the parasitic protozoa 82 2.7 Genomic and post genomic exploration of protozoan biology 83 2.8 Summary 87 2.9 General information on protozoa 88 References for further reading 88 3 Apicomplexa:Malaria 91 Tracey J. Lamb and Francis M. Ndung’u 3.1 Malaria 91 3.2 Recognition ofmalaria parasites 94 3.3 Innate effector mechanisms 95 3.4 Adaptive immunity 98 3.5 Memory responses 101 3.6 Immune evasion 101 3.7 Immunopathology 103 References for further reading 105 4 Apicomplexa: Toxoplasma gondii 107 EmmaWilson 4.1 Introduction 107 4.2 Life cycle and pathogenesis 107 4.3 Innate immune responses 111 4.4 Evasion strategies 113 4.5 Adaptive immune responses 115 4.6 CNS infection 117 4.7 Conclusions 118 References for further reading 118 5 Apicomplexa: Cryptosporidium 121 Jan R. Mead andMichael J. Arrowood 5.1 Life cycle 122 5.2 Clinical presentation 123 5.3 General immune responses in cryptosporidiosis 124 5.4 Innate effector mechanisms 125 5.5 Adaptive immunity 127 5.6 Memory responses 131 5.7 Antigens eliciting the immune response 132 5.8 Immune evasion 132 5.9 Immunopathology in the gut and intestinal tract 134 References for further reading 134 6 Diplomonadida: Giardia 139 Steven Singer 6.1 The life cycle and pathogenesis of Giardia infection 139 6.2 Recognition of Giardia by the immune system 141 6.3 Innate effector mechanisms against Giardia 142 6.4 Adaptive immunity against Giardia 143 6.5 Memory responses 145 6.6 Antigens eliciting the immune response 146 6.7 Immune evasion 147 6.8 Immunopathology 148 6.9 Summary 150 References for further reading 150 7 Kinetoplastids: Leishmania 153 IngridM¨ uller and Pascale Kropf 7.1 The pathogenesis of Leishmania infection 153 7.2 Life cycle 154 7.3 Parasite transmission and avoidance of immune responses 155 7.4 Innate effector mechanisms: the role of neutrophils in Leishmania infection 157 7.5 Adaptive immunity: lessons from L. major infections of mice 158 7.6 Arginase promotes Leishmania parasite growth 162 7.7 Memory responses 163 References for further reading 164 8 Kinetoplastids: Trypanosomes 165 Jeremy Sternberg 8.1 The African trypanosomes (Trypanosoma brucei ssp.) 165 8.2 Pathogenesis of sleeping sickness 167 8.3 Variant surface glycoprotein – the key to trypanosome-host interactions 168 8.4 The humoral response to African trypanosomes 172 8.5 T cell responses in African trypanosome infections 173 8.6 Innate defence mechanisms: trypanosome lytic factor 173 8.7 Immunopathology and VSG 174 8.8 Summary 175 References for further reading 176 9 Kinetoplastids: Trypanosoma cruzi (Chagas disease) 179 Rick Tarleton 9.1 Life cycle and transmission 180 9.2 Immune control and disease 181 9.3 Innate recognition of T. cruzi 182 9.4 Adaptive immunity 183 9.5 Regulation of immune responses and parasite persistence 186 9.6 Conclusions 189 References for further reading 189 Section 3 10 Introduction to Helminth Infections 195 David B. Guiliano 10.1 Acanthocephala 196 10.2 Nematodes 196 10.3 Pentastomida 203 10.4 Platyhelminthes 203 10.5 The evolution of parasitism within the helminths: divergent phyla with common themes 208 10.6 Genomic and post-genomic exploration of helminth biology 211 10.7 Summary 211 References for further reading 213 11 Nematoda: Filarial Nematodes 217 Sabine Specht and Achim Hoerauf 11.1 The life cycle and pathogenesis of filarial nematode infections 217 11.2 Animal models of filariasis 220 11.3 Immune responsesmounted against filarial nematodes 221 11.4 Innate immunity 221 11.5 Adaptive immunity 224 11.6 Immune evasion 225 11.7 Immunopathology 228 References for further reading 229 12 Nematoda: Ascaris lumbricoides 231 Christina Dold 12.1 Introduction 231 12.2 Ascaris infection displays an over-dispersed frequency distribution 232 12.3 Life cycle 232 12.4 Pathogenesis of infection 233 12.5 Animal models of Ascaris infection 234 12.6 Immune responses generated against the migratory phase of Ascaris 235 12.7 The cytokine response to Ascaris lumbricoides 237 12.8 The humoral response to Ascaris lumbricoides 238 12.9 Antigens eliciting immune responses in Ascaris infection 241 12.10 Conclusions 242 References for further reading 243 13 Nematoda: Hookworms 247 Soraya Gaze, HenryMcSorley and Alex Loukas 13.1 Pathogenesis of hookworminfection 247 13.2 The life cycle of hookworms 248 13.3 Animal models of hookworminfection 249 13.4 Innate immune responses to hookworms 251 13.5 Adaptive immunity 252 13.6 Cytokine responses 253 13.7 Antibody responses 254 13.8 Antigens eliciting the immune response 255 13.9 Memory responses 255 13.10 Immunoregulatory aspects of the anti-hookwormimmune response 256 13.11 Conclusion 258 References for further reading 259 14 Nematoda: Trichuris 263 Colby Zaph 14.1 Trichuris infection 263 14.2 Life cycle and pathogenesis 264 14.3 Immunity to Trichuris 265 14.4 Recognition by the immune system 265 14.5 Innate immune responses 265 14.6 Adaptive immune responses 269 14.7 Immune memory 269 14.8 Vaccines 270 14.9 Trichuris as a therapeutic 270 14.10 Summary 271 References for further reading 271 15 Nematoda: Trichinella 275 Judith A. Appleton, Lisa K. Blum and Nebiat G. Gebreselassie 15.1 Life cycle 275 15.2 Pathogenesis 277 15.3 Adaptive immunity 278 15.4 Immunopathology 282 15.5 Evasion strategies 283 References for further reading 284 16 Trematoda: Schistosomes 287 Mark Wilson 16.1 The schistosome life cycle 287 16.2 Immunological recognition of schistosomes 290 16.3 Innate effector mechanisms 291 16.4 Adaptive immunity 292 16.5 Memory responses 297 16.6 Schistosome antigens eliciting immune responses 298 16.7 Immune evasion 298 16.8 Schistosomiasis and immunopathology 299 References for further reading 303 17 Cestoda: Tapeworm Infection 307 C´esar A. Terrazas,Miriam Rodr´ýguez-Sosa and Luis I. Terrazas 17.1 The life cycle of tapeworms 307 17.2 Epidemiology 309 17.3 Pathology 310 17.4 Innate immunity 311 17.5 Adaptive immunity 312 17.6 Antigens eliciting the immune responses 315 17.7 Immunomodulation or evasivemechanisms 316 17.8 Echinococcosis 316 17.9 Conclusions 320 References for further reading 320 Section 4 18 Co-infection: Immunological Considerations 325 Joanne Lello 18.1 Co-infection is the rule rather than the exception 325 18.2 Interactions between co-infecting parasites 326 18.3 The Th1/Th2 paradigm in co-infection 327 18.4 Co-infection can alter disease severity 328 18.5 Modelling parasite interactions during co-infection 329 18.6 Co-infection as a therapy? 330 18.7 Consideration of co-infection in an ecological framework 331 18.8 Concluding remarks 332 References for further reading 333 19 HIV and Malaria Co-infection 335 Aubrey Cunnington and EleanorM. Riley 19.1 The endemicity of HIV and malaria 335 19.2 HIV infection 335 19.3 Immunopathogenesis of HIV 341 19.4 Interactions between malaria and HIV 343 19.5 Effect of co-infection on treatment of HIV and malaria infections 347 19.6 Combined effects of HIV and malaria on susceptibility to other diseases 348 19.7 Malaria and HIV vaccines 349 19.8 Summary 351 References for further reading 351 20 HIV and Leishmania Co-infection 353 JavierMoreno 20.1 Leishmania parasitaemia is increased in HIV-Leishmania co-infection 354 20.2 Leishmania infection increases viral replication rate 354 20.3 Cell specific interactions between HIV-1 and Leishmania 355 20.4 Immune response interactions between HIV-1 and Leishmania 357 20.5 Immune reconstitution inflammatory syndrome in HIV-1/Leishmania co-infection 358 References for further reading 359 21 Gastrointestinal Nematodes and Malaria 361 Mathieu Nacher 21.1 Introduction 361 21.2 Results from field studies in humans are conflicting 361 21.3 Immune responses in GI nematode and malaria co-infections 363 21.4 Stereotypical but different 370 21.5 Animal models of GI nematode-malaria co-infection 370 21.6 Conclusions 372 References for further reading 372 22 Malaria and Schistosomes 375 ShonaWilson and Jamal Khalife 22.1 The epidemiology of schistosomiasis and malaria co-infection 375 22.2 Study design for malaria/schistosome co-infection studies 376 22.3 Antibody responses 380 22.4 Cytokine responses 382 22.5 Contribution of experimental models to the understanding of Schistosoma mansoni and Plasmodium co-infection 384 22.6 Conclusions 385 References for further reading 385 Section 5 23 Hygiene and Other Early Childhood Influences on the Subsequent Function of the Immune System 391 Graham A.W. Rook 23.1 Introduction 392 23.2 The Hygiene Hypothesis (or ‘Old Friends’ hypothesis) 392 23.3 Epidemiological transitions 393 23.4 Compensatory genetic variants 394 23.5 The critical organisms and their immunological role 395 23.6 Helminth infections and allergic disorders 395 23.7 Helminths and non-allergic chronic inflammatory disorders: human data 396 23.8 Animal models of helminth infection used to test the Hygiene Hypothesis 397 23.9 Non-helminthic ‘Old Friends’ 397 23.10 Mechanisms of immunoregulation 398 23.11 Conclusions 399 References for further reading 400 24 Nematodes as Therapeutic Organisms 401 William Harnett andMargaretM. Harnett 24.1 Evidence that parasitic nematodes can protect humans from allergy and autoimmunity 401 24.2 Mechanism of action 404 24.3 Nematodemolecules involved in preventing allergic/autoimmune disease 408 24.4 Clinical aspects 412 References for further reading 413 25.1 Vaccination AgainstMalaria 417 AlbertoMoreno 25.1.1 Malaria vaccines: proof of concept 417 25.1.2 Vaccine development 419 25.1.3 Pre-erythrocytic vaccines 420 25.1.4 Erythrocytic vaccines 423 25.1.5 Transmission-blocking vaccines 425 25.1.6 Whole organism vaccines 426 25.1.7 P. vivax vaccines 427 25.1.8 Concluding remarks 429 References for further reading 429 25.2 Current Approaches to the Development of a Vaccine Against Leishmaniasis 431 Yasuyuki Goto and Steven G. Reed 25.2.1 Vaccination against leishmaniasis 432 25.2.2 Anti-amastigote vaccines 432 25.2.3 Anti-saliva vaccines 436 25.2.4 Transmission prevention vaccines 436 25.2.5 Role of an adjuvant in vaccine development 436 25.2.6 Future directions 438 References for further reading 438 25.3 Vaccination Against Hookworms 441 Brent Schneider,Maria Victoria Periago and Jeffrey M. Bethony 25.3.1 The need for a vaccine 441 25.3.2 The Human HookwormVaccine Initiative 442 25.3.3 The history of hookwormvaccines: experiments in dogs 443 25.3.4 Antibody production against canine hookworm 443 25.3.5 Vaccination against hookwormwith irradiated larvae 444 25.3.6 Lessons from vaccination with irradiated larvae 445 25.3.7 Research identifying target proteins for an anti-hookwormvaccine 446 25.3.8 A human hookwormvaccine phase 1 clinical trial based on Na-ASP2 453 25.3.9 The HHVI takes a different approach 454 25.3.10 Developments through the last century and the future 455 References for further reading 456 25.4 Current Approaches to the Development of a Vaccine Against Filarial Nematodes 459 Sara Lustigman 25.4.1 Introduction to anti-filarial nematode vaccines 459 25.4.2 Anti-O. volvulus and anti-LF vaccines are a valid approach to advance control measures against onchocerciasis and lymphatic filariasis 461 25.4.3 Future directions for vaccine development 466 25.4.4 Discovery of new vaccine candidates 467 References for further reading 468 Abbreviations 471 Glossary 479 Index 493

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Book SynopsisTable of Contents1 Introduction 2 The mouth as a microbial habitat 3 The resident oral microbiota 4 Distribution, development and benefits of the oral microbiota 5 Dental plaque 6 Plaque-mediated diseases: Dental caries and periodontal diseases 7 Orofacial bacterial infections 8 Oral fungal infections 9 Orofacial viral infections 10 Antimicrobial agents 11 Oral microbiota and systemic disease 12 Infection control

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Book SynopsisAn essential resource for practitioners in infectious diseases and microbiology, studying for the new FRCPath Part 1 infection examination accredited by the Royal College of Pathologists, and trainees sitting the membership exams of the Royal College of Physicians. Including over 300 multiple choice questions in an exam-style Q&A format, this guide provides an invaluable revision platform for domestic and international trainees alike, with scope to present infection-based support for other medical specialties, where infection forms a core component, including intensive care. Authored by leading specialists in infectious diseases and microbiology, this invaluable training guide is the first of its kind to cover both undergraduate and postgraduate material in infectious diseases. Mapping directly from the FRCPath and RCP infection curricula, students are able to explore areas of curriculum to gain knowledge and optimise decision-making skills, under pressure.Trade Review'An extremely useful resource for trainees in any speciality wanting to expand their knowledge about infection related issues or for trainees in microbiology and infectious diseases preparing for examinations. The content of this book spans the recently updated infection training curriculum; from the biology of microorganisms and laboratory practices, to clinical syndromes and the treatment of infections, to infection control, outbreak management and approaches to the returning traveller. The 'best of five' approach adopted by the authors is extremely effective; not only reflecting the current examination format, but it also promoting active learning by making the reader think about the topic area prior to consulting the clear and accurate answers provided by the authors. A must-have for anyone undertaking training in microbiology and infectious diseases or for anyone with an interest in infectious diseases wishing to update their knowledge.' Sanjay Patel, University Hospital Southampton'This is an excellent book covering a wide variety of infectious diseases. The first four chapters are very helpful in understanding pathogen biology and the role of the microbiology laboratory in infectious diseases. These will be an excellent quick read for trainees going into infectious disease specialization training. Although many of the questions are not written in the style of US boards, much of the information has some relevance to the ABIM infectious disease exam.' Rajendra Karnatak, Doody's Book Review ServiceTable of ContentsPreface; Reference ranges; Abbreviation; 1. Biology of bacteria, viruses, fungi and parasites and the host-pathogen interactions; 2. Microbiology and virology laboratory practice; 3. Health and safety for infectious diseases, microbiology and virology; 4. Principles of public health in relation to infectious diseases, microbiology and virology; 5. Infection prevention and control; 6. Important clinical syndromes presenting from the community and within healthcare organisations; 7. Understanding use of antimicrobial agents; 8. Vaccination; 9. The management of HIV infection; 10. Travel and geographical health; Imported infection and the provision of pre-travel health advice; Index.

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Book SynopsisCrisis and Contagion is a selection of fourteen interviews conducted by Ian McKay of the Wilson Institute at McMaster University. Interviews with Nancy Fraser, Mike Davis, Mack Penner, Andreas Malm, and Merrill Singer explore capitalism’s organic crisis and the ways it has made this and future pandemics inevitable. Nora Loreto, Tithi Bhattacharya, Chandrima Chakraborty, Merlin Chowkwanyun, and Sanjay Nepal discuss the experiences of ordinary people in the pandemic. J. Michael Ryan, Laura Spinney, Naomi Klein, and Noam Chomsky explore the long-term effects and likely historical legacy of a pandemic that has changed millions of lives–and, maybe, the trajectory of human civilization. These scholars propose that to understand the impact of Covid-19, we have to understand the conflictual history of capitalism–and to ward off future pandemics, we need to start building a post-capitalist alternative to the disease-generating and highly unequal global neoliberal order. As capitalist forces work to shove what we have learned from the Covid-19 pandemic down the memory hole, Crisis and Contagion offers a must-read for those wanting to seize this moment of change and revolution.Trade Review“While global profit-seekers and the states that protect them push to normalize the Covid-19 pandemic, Crisis and Contagion conveys the urgency of international solidarity amongst the wretched of the earth. There is nothing natural about the premature deaths and disposability caused by our current world order. The interviews in this book provide us with the sharp analysis we need to understand that the social and material crises inherent to capitalism are as mutable as the virus.” - Nanky Rai, MD MPH CCFP, physician and organizer with the Toronto Overdose Prevention Society and Toronto Street Medics // “This immersive, wide-ranging collection of interviews reveals many potential ways forward for organizers and activists to reclaim health as politics, away from the control of technocrats and professionals. These engaging, personable interviews rightly contextualize Covid-19 as an expression of multiple crises created by capitalism—with its atomization and commodification—which beg for a transformative vision from the Left. Crisis and Contagion is essential reading for all those invested in centering health, care, justice, and liberation in the world we are now building.” – Baijayanta Mukhopadhyay, MA MD CCFP DTM&H, author of Country of Poxes and A Labour of Liberation, co-coordinator of People’s Health Movement CanadaTable of ContentsAcknowledgements Introduction Part One: The Organic Crisis of Neoliberal Capitalism Nancy Fraser Mike Davis Mack Penner Andreas Malm Merrill Singer Part Two: Sacrificing the Subalterns Nora Loreto Tithi Bhattacharya Chandrima Chakraborty Merlin Chowkwanyun Sanjay Nepal Part Three: Choppy Waters Ahead J. Michael Ryan Laura Spinney Naomi Klein Noam Chomsky Notes Index

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Book SynopsisTable of ContentsPreface to the First Edition Preface to the Twenty-Fourth Edition Contributors 1 History of Tropical Medicine, and Medicine in the Tropics SECTION I 21st Century Drivers of Tropical Medicine 2 Global Health 3 Poverty and Inequality 4 Public Health in Settings of Conflict and Political Instability 5 Climate Change and Health in the Tropics: Current Status and Future Trends 6 Medical Products Quality and Public Health 7 The Economic Case for Devoting Public Resources to Health 8 Global Health Governance and Tropical Diseases SECTION II Health Research and Ethics 9 Ethics and Tropical Diseases: Some Global Considerations SECTION III Epidemiology 10 Issues and Challenges of Public Health Research in Developing Countries SECTION IV Clinical Assessment 11 Emergency and Intensive Care Medicine in Resource-Poor Settings 12 Ultrasound 13 Surgery in the Tropics SECTION V Viral Infections 14 HIV Epidemiology in the Tropics 15 Clinical Features and Management of HIV/AIDS in Adults 16 HIV in Children 17 HIV/AIDS Prevention 18 Viral Hepatitis 19 Yellow Fever 20 Arbovirus Infections 21 Dengue 22 Viral Haemorrhagic Fevers 23 Rabies 24 Rotavirus and Other Viral Diarrhoea 25 Respiratory Viruses and Atypical Bacteria 26 Viral Exanthems 27 Virus Infections of the Nervous System 28 COVID-19 SECTION VI Bacterial Infections 29 Tropical Rickettsial Infections 30 Sexually Transmitted Infections (Excluding HIV) 31 Bacterial Enteropathogens 32 Salmonella Infections 33 Pneumococcal Disease 34 Bacterial Meningitis 35 Brucellosis 36 Noma, Actinomycosis, and Nocardia 37 Bartonellosis, Cat-scratch Disease, Trench Fever, Human Ehrlichiosis 38 Anthrax 39 Tetanus 40 Plague 41 Melioidosis 42 Diphtheria 43 Spirochaetes Diseases of the Tropics SECTION VII Fungal Infections 44 Superficial and Subcutaneous Mycoses 45 Systemic Mycoses SECTION VIII Mycobacterial Infections 46 Tuberculosis 47 Leprosy 48 Mycobacterium ulcerans Disease (Buruli Ulcer) SECTION IX Protozoan Infections 49 Malaria 50 Babesiosis 51 Human African Trypanosomiasis 52 American Trypanosomiasis: Chagas Disease 53 Leishmaniasis 54 Toxoplasmosis 55 Intestinal Protozoa 56 Pathogenic and Opportunistic Free-Living Amoebae: Agents of Human and Animal Disease SECTION X Helminthic Infections 57 Schistosomiasis 58 Food-borne Trematodes 59 The Filariases 60 Soil-Transmitted Helminths (Geohelminths) 61 Cystic, Alveolar and Neotropical Echinococcosis 62 Other Cestode Infections: Intestinal Cestodes,Cysticercosis, Other Larval Cestode Infections SECTION XI Ectoparasites 63 Scabies 64 Human Lice, Bed Bugs, Sand Fleas, Myiasis, and Leeches SECTION XII Non-communicable Diseases in the Tropics 65 Non-Communicable Diseases: Equity, Action, and Targets 66 Cardiovascular and Vascular Disease in the Tropics Including Ischaemic Heart Disease, Stroke, and Hypertension 67 Diabetes in the Tropics 68 Cancer in the Tropics 69 Haematological Diseases in the Tropics 70 Renal Disease in the Tropics 71 Ophthalmology in the Tropics and Sub-tropics 72 Dermatological Problems in the Tropics 73 Musculoskeletal Disorders 74 Respiratory Problems in the Tropics 75 Tropical Neurology 76 Psychiatry 77 Oral Disease in the Tropics SECTION XIII Environmental Disorders 78 Environmental Stress 79 Venomous and Poisonous Animals 80 Plant Poisons, Hallucinogens, and Traditional Medicines SECTION XIV Nutrition 81 Nutrition-Associated Disease 82 Obesity in the Tropics SECTION XV Maternal/Child Health 83 Obstetrics in the Tropics 84 Paediatrics in the Tropics Appendices Appendix 1: Clinical Laboratory Diagnosis Appendix 2: Parasitic Protozoa Appendix 3: Medical Helminthology Appendix 4: Medical Acarology and Entomology Appendix 5: Sources of Information in Tropical Medicine Index

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Book Synopsis**THE SUNDAY TIMES BESTSELLER**'Brilliant! It's hard to change your life - but this book gives you all the reasons it's possible. From the first page to the last, one revelation after another.'JEREMY VINE'Brilliant . . . especially required reading in these COVID-19 days'LIZ EARLE'Metabolism, inflammation, and immunity are three sides of the same coin. Fix one and you fix them all. Dr Aseem Malhotra offers you a way to fix all three at once, and the solution is as easy as your fork.' PROFESSOR ROBERT LUSTIG, bestselling author of Fat Chance'This remarkable book will change your life. Beautifully written, it compiles in one place the health messages we all know make sense. PROFESSOR KAROL SIKORA, leading cancer specialist and Founding Dean, University of Buckingham Medical School'Read this book and follow the plan, it may save your life.' GURINDER CHADHA, OBE, director of Bend It Like Beckham'A crystal-clear roadmap to reverse the roots causes of our poor metabolic and immune health. It is the handbook of health for our time.' MARK HYMAN, New York Times bestselling author of Food Fix*******The simple, evidence-based diet plan to rapidly improve your metabolic health, help with normal immune function and likely reduce the risk of severe effects from Covid-19.Dr Aseem Malhotra is a leading NHS-trained cardiologist and a pioneer of lifestyle medicine. He has been at the forefront of citing the health conditions which make us vulnerable to the worst effects of Covid-19. Obesity, Type 2 diabetes and heart disease are high among them - and all indicators of poor metabolic health. The good news is that in just 21 days we can prevent, improve and even potentially reverse many of the underlying risk factors that exacerbate how infections, including Covid-19, affect us and improve our ability to recover from them. Giving us the evidence-based science behind the plan, Dr Malhotra shares how simple changes to our diet as well as daily exercise and stress relief can have remarkable results in improving our markers for metabolic health, even helping to put Type 2 diabetes into remission, reduce risk factors for heart disease, decrease weight and enhance vitality.Arguing for the huge benefits to global health of these highly effective lifestyle changes, he shows how just 21 days can help us to start the journey to lead a healthier and longer life.Trade Review'This valuable and timely book is a must read.' -- KIM PEARSON, Harley Street nutritionist * London Evening Standard *'You have to get immediately The 21 Day immunity plan and take action now.' * European Scientist *'Dr Aseem Malhotra is a quite remarkable man . . . his timely, evidence-based and brilliant new 21-day immunity plan is a perfect way to take the first step to transforming your life. I wish you well on your journey to better health.' -- From the Foreword by TOM WATSON'I've been unfortunate enough to have had #COVID19. I feel had I not focused on regaining my metabolic health and sending my type 2 diabetes into remission things could have been much worse. This amazing Doctor puts his head above the parapet. I have great respect for Dr Aseem Malhotra and owe my regained metabolic health to him.' -- DEBRA SCOTT, retired civil servant'Feel good today and increase your chance of living a longer and healthier life. In this well researched book Dr Malhotra provides the science and the steps for this double win.' -- DR CAMPBELL MURDOCH, Clinical Adviser, Royal College of GPs'This game-changing book is a must-read for anyone wishing to understand the link between metabolic health and immunity.' -- DR RAVI KUMAR KAMEPALLI, Board-Certified in Infectious Diseases, Wound Care and Obesity Medicine, Augusta, USA'Dr Aseem Malhotra spells it all out right here in front of you, with a perfect combination of smart, simple strategies for prevention or management of lifestyle conditions and keeping the immune system in best shape.' -- DR CARYN ZINN, Senior Lecturer, Dietitian, AUT University, Head of Research – School of Support and Recreation, Auckland, New Zealand'This groundbreaking book empowers the reader with knowledge of the practical steps we can all take to improve our health status and protect ourselves against diseases of all kinds.' -- KIM PEARSON, Harley Street nutritionist'Brilliant . . . especially required reading in these COVID-19 days' -- Liz Earle

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Book SynopsisThis book details out the esoteric history of biological warfare in a way that no other book has done, based on only official records, documents, science and medical journals, former intelligence officers, and more. The history of this war goes much deeper than any other book on the subject has presented, based on understandings and studies of science that have been purposefully buried and obscured. The author collected and studied the work of one of history’s most exceptional yet infamous pioneers in virology and immunology, a German scientist by the name of Dr. Erich Traub, for several years, in the process of writing this book, a process which perhaps no one else has managed to undertake, until now.

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Book SynopsisSelected as a Doody's Core Title for 2022 and 2023! Now in four convenient volumes, Fields Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Fields Virology: Emerging Viruses, Seventh Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, including coronavirus and COVID-19, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases. Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesis. Covers virus evolution, as well as Coronoviridae, Picornaviridae, Enteroviruses, Caliciviridae, Hepatitis C Virus, Filoviridae, Henipaviruses, Orthomyxoviruses, Bunyavirales, Arenaviridae, and much more. Features over 500 full-color illustrations, including key figures for use as lecture slides. Provides quick, flexible access to current information both in print and in an improved eBook format, searchable across all volumes. Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, virus evolution and immunization. New and forthcoming Fields Virology volumes, available in print and eBook format, which are sold separately: Emerging Viruses DNA Viruses RNA Viruses Fundamental Viruses Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

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Book SynopsisNow in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: RNA Viruses, Seventh Edition covers the latest information on RNA viruses, how they cause disease, how they can cause epidemics and pandemics, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field.Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases. Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesis Includes two new chapters on SARS - Coronavirus 2 covering both basic science and clinical aspects of CoV2 and COVID-19 Covers human immunodeficiency virus (HIV), rotaviruses, respiratory syncytial virus (RSV), measles virus, and more Features more than 400 full-color illustrations, including key figures for use as lecture slides Provides quick, flexible access to current information both in print and in an improved eBook format Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, viral persistence and latency for HIV, and mechanisms of viral oncogenesis for HTLV-1 and HCV New and forthcoming Field’s Virology volumes, available in print and eBook format:• Emerging Viruses - 2020• DNA Viruses - 2021• RNA Viruses• Fundamental Virology Enrich Your eBook Reading Experience Read directly on your preferred device(s),such as computer, tablet, or smartphone. Easily convert to audiobook,powering your content with natural language text-to-speech.

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Book SynopsisA virologist's insight into how viruses evolve and why global epidemics are inevitableIn 1993 a previously healthy young man was drowning in the middle of a desert, in fluids produced by his own lungs. This was the beginning of the terrifying Sin Nombre hantavirus epidemic and the start of a scientific journey that would forever change our understanding of what it means to be human.After witnessing the Sin Nombre outbreak, Dr Frank Ryan began researching viral evolution and was astonished to discover that it's inextricable from the evolution of all life on Earth. From AIDS and Ebola to the common cold, Ryan explores the role of the virus within every ecosystem on the planet. His gripping conclusions shed new light on the natural world, proving that what doesn't kill you really does make you (and your species) stronger.Trade ReviewPraise for Virusphere: ‘A fascinating book that is well structured … absorbing … [and] makes an engrossing and fervent argument’ The Inquisitive Biologist Praise for Frank Ryan: 'Extremely well written … Frank Ryan has the page-turning and spine-chilling ability of a good novelist'Sunday Telegraph 'Ryan is very good at making technical matters comprehensible to the lay reader, but more impressive still is the away he conveys the intellectual excitement and elation of scientific discovery'Literary Review ‘Dr Ryan writes well in a difficult technical field, weaving the technicalities of scientific history, medicine, molecular biology and evolution into the human narratives … Very readable and disturbing’New York Times…

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Book SynopsisTable of ContentsPreface 1. What are viruses, and how were they discovered? 2. Viruses and their particles 3. Virus origins and genetics 4. Virus genomes and their replication 5. Expression of virus genomes 6. Infection and immunity 7. Viral pathogenesis 8. Panics and pandemics 9. Subviral agents: Deltaviruses and prions Appendix 1 Index

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Book SynopsisCelebrated science writer Carl Zimmer’s classic book, updated in a new edition, is an eye-opening look at Covid-19 and the many other viruses that shape our planet and ourselves.Trade Review"A smart, beautiful, and somewhat demented picture book that's likely to give you a case of the willies. In the best way possible."-- "Boing Boing, on the first edition" "Absolutely top-drawer popular science writing. . . . Zimmer's information-packed, superbly readable look at virological knowledge awakens readers to the fact that not only are viruses everywhere but we couldn't live without them."-- "Booklist, starred review, on the first edition" "As with any great journey, this virtual tour opens your eyes and expands your horizons. . . . Reading Zimmer's work is like hanging out with the smartest, most interesting guy you have ever met as he regales you with tales of his travels and fascinating finds along the way."-- "Science News, on the first edition" "Just about everything you've always wanted to know--and a lot you'll probably wish you didn't know--about the viruses that have caused humanity so much grief throughout history."-- "Forbes, on the first edition" "Succinct yet elegantly written. . . . A fascinating and enlightening introduction."-- "Guardian, on the first edition" "Zimmer reshapes our understanding of the hidden realities at the core of everyday existence. . . . Concise and illuminating."-- "Washington Post, on the first edition" "Zimmer is one of the best science writers we have today. A Planet of Viruses is an important primer on the viruses living within and around all of us--sometimes funny, other times shocking, and always accessible. Whether discussing the common cold and flu, little-known viruses that attack bacteria or protect oceans, or the world's viral future as seen through our encounters with HIV or SARS, Zimmer's writing is lively, knowledgeable, and graced with poetic touches."--Rebecca Skloot, author of The Immortal Life of Henrietta Lacks "on the first edition"

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Book SynopsisAn empathic and practical guide to navigating life with the cognitive and mental health impairments that accompany Long Covid, from neuropsychologist and world-renowned Long Covid expert Dr. James C. Jackson.Trade ReviewClearing the Fog is a thoughtful and practical resource for people with long Covid. Dr. Jackson draws on his own personal experiences with managing his mental health as well as the experiences of his patients to provide a guide on how to manage the challenges of long Covid. -- Dr Sanjay Gupta, author of Keep SharpDr. Jackson expertly and compassionately explores the realities of Long Covid-from anxiety to brain fog-and reveals the actions we can take to support and empower ourselves and our loved ones. An essential guide for everyone touched by Long Covid. -- Dr Mark Hyman, author of Young ForeverDr. Jim Jackson, displaying his deep expertise and even deeper humanity, has produced a guide that provides a path forward for people living with long COVID, and for many more managing other severe, chronic conditions. The sheer abundance of useful strategies is astonishing-and conveyed in ways that are uplifting and encouraging. This book is sure to transform lives, enabling people to make meaningful progress despite dire health challenges. -- Dr. Harlan Krumholz, Director of the Center for Outcomes Research and Evaluation, Yale School of MedicineClearing the Fog is full of invaluable-potentially life-saving-information and could be an indispensable handbook for millions of patients. Dr. Jackson clearly lays out how to accept your illness, take steps to find specialist health providers or support services, and build a new life amid Long Covid. Following these steps may well save your career, your marriage, or your most deeply held dreams. -- Ryan Prior, author of The Long HaulFor two decades, I've witnessed my colleague, Dr. Jim Jackson, expertly care for and support patients struggling with newly-acquired cognitive impairment and mental health difficulties after illness and into survivorship. His wisdom and empathy-on display throughout the pandemic in his treatment of patients with Long Covid-is distilled here on the pages of Clearing the Fog, a kind, profoundly human, and practical resource for long haulers, their families, and Health Care professionals. Grounded in science and guided by compassion, Clearing the Fog presents a way forward to the millions navigating Long Covid and other chronic illnesses such as ME/CFS, Long Lyme, or fibromyalgia, people who have been dismissed for far too long. Dr. Jackson has listened to their concerns and provides solutions wherever possible and empathy when answers remain elusive. His book fulfills a driving unmet need in the literature and will bring hope to many. -- Dr Wes Ely, author of Every Deep-Drawn BreathA timely and essential book. Jackson is a world-renowned expert on the effects of illness on cognitive functioning, and he seamlessly weaves together patient narratives, his own personal struggles, and cutting-edge research to create a uniquely empowering and insightful book. Clearing the Fog is not only for those suffering from Long Covid; it should be read by family members, by healthcare workers, by anyone who has been touched by this pandemic-which is, ultimately, all of us. -- Daniela Lamas, author of You Can Stop Humming NowClearing the Fog is a thoughtful and practical resource for people with long Covid. Dr. Jackson draws on his own personal experiences with managing his mental health as well as the experiences of his patients to provide a guide on how to manage the challenges of long Covid. -- Sanjay Gupta, author of Keep SharpDr. Jackson expertly and compassionately explores the realities of Long Covid-from anxiety to brain fog-and reveals the actions we can take to support and empower ourselves and our loved ones. An essential guide for everyone touched by Long Covid. * Dr Mark Hyman, author of Young Forever *Dr. Jim Jackson, displaying his deep expertise and even deeper humanity, has produced a guide that provides a path forward for people living with long COVID, and for many more managing other severe, chronic conditions. The sheer abundance of useful strategies is astonishing-and conveyed in ways that are uplifting and encouraging. This book is sure to transform lives, enabling people to make meaningful progress despite dire health challenges. * Dr. Harlan Krumholz, Director of the Center for Outcomes Research and Evaluation, Yale School of Medicine *Clearing the Fog is full of invaluable-potentially life-saving-information and could be an indispensable handbook for millions of patients. Dr. Jackson clearly lays out how to accept your illness, take steps to find specialist health providers or support services, and build a new life amid Long Covid. Following these steps may well save your career, your marriage, or your most deeply held dreams. * Ryan Prior, author of The Long Haul *For two decades, I've witnessed my colleague, Dr. Jim Jackson, expertly care for and support patients struggling with newly-acquired cognitive impairment and mental health difficulties after illness and into survivorship. His wisdom and empathy-on display throughout the pandemic in his treatment of patients with Long Covid-is distilled here on the pages of Clearing the Fog, a kind, profoundly human, and practical resource for long haulers, their families, and Health Care professionals. Grounded in science and guided by compassion, Clearing the Fog presents a way forward to the millions navigating Long Covid and other chronic illnesses such as ME/CFS, Long Lyme, or fibromyalgia, people who have been dismissed for far too long. Dr. Jackson has listened to their concerns and provides solutions wherever possible and empathy when answers remain elusive. His book fulfills a driving unmet need in the literature and will bring hope to many. * Dr Wes Ely, author of Every Deep-Drawn Breath *A timely and essential book. Jackson is a world-renowned expert on the effects of illness on cognitive functioning, and he seamlessly weaves together patient narratives, his own personal struggles, and cutting-edge research to create a uniquely empowering and insightful book. Clearing the Fog is not only for those suffering from Long Covid; it should be read by family members, by healthcare workers, by anyone who has been touched by this pandemic-which is, ultimately, all of us. * Daniela Lamas, author of You Can Stop Humming Now *

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Book SynopsisAn empathic and practical guide to navigating life with the cognitive and mental health impairments that accompany Long Covid, from neuropsychologist and world-renowned Long Covid expert Dr. James C. Jackson.

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Book Synopsis

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Book SynopsisA timely and urgent investigation from John Vidal, Environment Editor of the Guardian for nearly thirty years, into how the destruction of nature is releasing disease into our societies''Urgent, fascinating and essential'' GEORGE MONBIOT''A searing, vital work'' BETTANY HUGHESCovid-19, mpox, bird flu, SARS, HIV, AIDS, Ebola; we are living in the Age of Pandemics one that we have created. As the climate crisis reaches a fever pitch and ecological destruction continues unabated, we are just beginning to reckon with the effects of environmental collapse on our global health.Fevered Planet exposes how the way we farm, what we eat, the places we travel to and the scientific experiments we conduct create the perfect conditions for deadly new diseases to emerge and spread faster and further than ever. Drawing on the latest scientific research and decades of reporting from more than 100 countries, former Guardian

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Book SynopsisA new coronavirus, most likely spilled over from an animal species, has plunged us into the third epidemic of this kind in the last twenty years, against which there were neither vaccines nor therapies.While we argue over the future of humanity, vulnerable to the ecological and environmental degradation that has enabled the pandemic, extraordinary technologies have been developed to combat infectious diseases. In just eleven months it was possible to develop, test and produce the vaccines that are gradually enabling us to escape the SARS-CoV-2 nightmare. In addition, with the legacy of the technologies developed against COVID-19, we will be able to overcome antimicrobial resistance—a slow but inexorable pandemic.As vaccinologists are churning out increasingly precise and effective solutions, vaccine acceptance seems to be receding. Outbreaks of preventable diseases have prompted the health authorities of several countries to make childhood vaccinations mandatory again. Much remains to be done, but a public capable of distinguishing authoritative voices from misleading ones will be able to enjoy the vaccines of tomorrow more widely. Vaccines in the Global Era is an easy-to-read book that can be read by virtually anyone who wants to learn about the importance, effectiveness and safety of vaccines in preventing infectious diseases.Vaccines are cheap, save countless lives, and are more effective than the best medicines. Let's try to make the best use of them for the health of the people and animals living together on this beautiful planet.

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Book SynopsisIn 1831, an unknown, horrifying and deadly disease from Asia swept across Continental Europe, killing millions in its path and throwing the medical profession into confusion. Cholera is a killer with little respect for class or wealth. When it arrived in Britain, its repercussions rocked Victorian England - from the filthy lanes of the Sunderland quayside and the squalid streets of Soho, to the great centres of power: the Privy Council, Whitehall and the Royal Medical Colleges. One man - alone and unrecognized - uncovered the truth behind the pandemic and laid the foundations for the modern scientific investigation of today's fatal plagues. John Snow was a reclusive doctor, without money or social position, who had the genius to look beyond the conventional wisdom of his day and work out that cholera was spread through drinking water. The book draws extensively on nineteenth-century medical, political and personal records in order to describe what is both an important breakthrough for medical science and also a dramatic story with a cast of colourful characters, from the heroic to the frighteningly incompetent. The book is also full of fascinating diversions into aspects of medical and social history, from Snow's tending of Queen Victoria in childbirth, to the Dutch microbiologist Leeuwenhoek's breeding of lice in his socks, and from Dickensian children's farms to riotous nineteenth-century anaesthesia parties.Trade ReviewRipping yarns from the dawn of proper medicine -- Ben Goldacre * Guardian *

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Book Synopsis'The authors of this absorbing book have a strong command of detail, context and narrative structure... the results are impressively claustrophobic.' - Times Literary Supplement'Gripping... The authors skillfully capture the fear and claustrophobia. A riveting real-life drama.' - Kirkus'Cabin Fever is riveting, taut, and extensively researched. Smith and Franklin have written a page-turning adventure that will keep you reading late into the night.' - Martin Dugard, #1 New York Times bestselling author of Taking Paris'A gripping account of how an invisible stowaway - the Covid-19 virus - transformed a fun-filled luxury cruise into an unimaginable nightmare.' - Sara Gay Forden, bestselling author of House of Gucci'Extensive first-hand testimony and the authors' brisk, matter-of-fact style enrich this propulsive account of how a holiday cruise turned into a nightmare. Readers will be riveted.' - Publishers WeeklyIn early 2020, the world was on edge. An ominous virus was spreading and no one knew what the coming weeks would bring. Far from the hotspots, the cruise ship Zaandam was preparing to sail from Buenos Aires loaded with 1,200 passengers - British, American, Australian, European and South American tourists, plus 600 crew. Most passengers were over the age of 65.There was concern about the virus in the news but that was oceans away. Escaping to sea at the ends of the earth for a few weeks seemed like it might be a good option. The cruise line had said the voyage would go ahead as scheduled and it would be safe. Within days, people aboard the Zaandam began to fall sick. The world's ports shut down. Zaandam became a top story on the news and was denied safe harbour everywhere. With only two doctors aboard and few medical supplies to test for or treat Covid-19, and with dwindling food and water, the ship wandered the oceans on an unthinkable journey.Cabin Fever is a riveting narrative thriller, taking readers behind the scenes of the ship's complex workings, and below decks into the personal lives of passengers and crew who were caught unprepared for the deadly ordeal that lay ahead. It is a story layered with moments of peril, perseverance and kindness. A remarkable tale that is filled with individual acts of heroism and the struggles and the tragedies of the crew and passengers.Trade Review'The authors of this absorbing book have a strong command of detail, context and narrative structure... the results are impressively claustrophobic.' -- Henry Hitchings * Times Literary Supplement *

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Book SynopsisExplore the microscopic world of bacteria, viruses and other microbes with this fascinating lift-the-flap book. Discover how germs spread, how the immune system works, the amazing vaccines and antibiotics humans have created, and much more. With Usborne Quicklinks to websites for activities and videos and up to date information about coronavirus.Table of Contents1 WHAT ARE GERMS?2 GOOD AND BAD BACTERIA3 VICIOUS VIRUSES4 PESKY PROTOZOA5 FASCINATING FUNGI6 SPREADING GERMS7 NATURAL DEFENCES8 VACCINES9 ANTIBIOTICS10 SUPERBUGS11 MICROBE HEROES

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Book SynopsisTrade Review"A New Statesman Essential Non-Fiction Book of 2021""Winner of the PROSE Award in the History of Science, Medicine, and Technology, Association of American Publishers""A Choice Outstanding Academic Title of the Year""[A] superb new history of infectious disease. Be so grateful you live now!"---David Frum"Magisterial. . . . [Harper’s] mastery of the science is only matched by the ease of his prose. If I were to nominate a book of the year, it would be this one."---Andrew Sullivan, The Dishcast"[A] sweeping masterpiece. . . . It’s difficult for me to think of anyone who will not find something eye-opening and enlightening in the pages of this comprehensive, beautifully written and eloquent book." * Forbes *"Plagues upon the Earth is a remarkable achievement."---Talha Burki, The Lancet"This magnificent book stood out as much for its nuance and academic rigour as it did for its readability." * Inquisitive Biologist *"An ambitious, engaging, and unified history of humanity’s interaction with infectious disease."---Gregory J. Morgan, Science"By integrating history, demography, economics, evolutionary biology and genomics into a seamless narrative, [Harper] does something that I, for one, have never seen before done so eloquently or persuasively: he demonstrates that any thorough understanding of health requires the kind of sweeping perspective that the humanities offers."---Steve Mintz, Inside Higher Ed"Comprehensive."---Tyler Cowen, Marginal Revolution"A remarkable accomplishment that weaves together microbiology, history, and economics to understand the role of diseases in shaping human history. Harper, an established historian known for his first three books on Rome and late antiquity, has an impressive command of virology, bacteriology, and parasitology as well as history and economics. In 'Plagues Upon the Earth.' he explains all of these clearly and with many arresting turns of phrase and insights."---Alex Tabarrok, Marginal Revolution"Well-conceived. … [Kyle] Harper combs through the literature of history, economics, epidemiology, and other disciplines to deliver a solid study of the role of infectious disease in the human story. ... Harper’s long-view study is a welcome addition to the spate of recent books on epidemic disease." * Kirkus Reviews *"This is a solid book, superbly referenced and interdisciplinary, covering disease from pre-human origins to the present, and making extensive use of published DNA comparisons and descriptions of plagues by historical observers." * Choice *"Completing the reading of this book leaves one with more than a feeling of satisfaction. Admiration for a major task that was written in an engaging style that retains a facile elegance throughout its 700 pages, that presents comprehensive and detailed information as though it were the sort of material that readers come across every day, is what one might not expect, but welcomes, in a serious work of this size."---Ian Lipke, Queensland Reviewers Collective"This timely work is the book of extraordinary brilliance and scope and the most significant in the field since William McNeill’s Plagues and Peoples from the mid-1970s."---David Lorimer, Paradigm Explorer"Magisterial." * Prospect *"Plagues Upon the Earth is a highly provoking and enjoyable read. It shows that our success as a species is equally paralleled to the success of pathogens"---Makayla Alderson Fox, World History Encyclopedia

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Book SynopsisAlthough an effective human rabies vaccine has existed since 1885, rabies continues to kill an estimated 59,000 people every year. Sixty per cent of these human deaths occur in Asia. The number of animals, especially dogs, who die of rabies is uncalculated. To work towards the global target of eliminating dog-mediated human rabies deaths, the rabies community is applying the One Health approach by jointly focusing on humans and dogs.Written by a multidisciplinary group of scholars and rabies control programme specialists, this book is a collection of experiences and observations on the challenges and successes along the path to rabies control and prevention in Asia. The book:-grounds chapters in solid scientific theory, but retains a direct, practice-focused and inspirational approach;-provides numerous examples of lessons learned and experience-based knowledge gained across countries at different levels of rabies elimination;-brings together and highlights the practices of a strong, international rabies network that works according to the One Health concept.Covering perspectives from almost a dozen Asian countries and a wide range of sectors and disciplines, such as healthcare facilities, veterinary services, laboratories, public health institutes, wildlife research centres and academia, this book is an invaluable resource for rabies practitioners and scholars, but also those working in the wider fields of disease control and cross-sectoral One Health.

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Book SynopsisNathan Wolfe is the Lorry I. Lokey Visiting Professor in Human Biology at Stanford University and Director of Global Viral Forecasting, a pandemic early warning system which monitors the spillover of novel infectious agents from animals into humans. Wolfe has been published in or profiled by Nature, Science, The New York Times, The New Yorker, The Economist, Forbes and many others. Wolfe was the recipient of a Fulbright fellowship in 1997 and was awarded the National Institutes of Health (NIH) International Research Scientist Development Award in 1999 and the prestigious NIH Director's Pioneer Award in 2005.Trade ReviewNathan Wolfe is saving the world from near-inevitable pandemic ... a kick-ass book -- Mary Roach, author of StiffAn excellent piece of scientific gothic, rich in descriptions of the threat we face from emerging viruses ... thought-provoking * Nature *Part autobiography, part warning ... enthralling * BBC Focus *Quietly terrifying ... It's hard not to feel a bit feverish at times while reading * Boston Globe *Wolfe has an important story to tell and as a virologist at the forefront of pandemic forecasting, he is the perfect person to tell it. He explains the science clearly and never stoops to sensationalism - the evidence of our increasing vulnerability to pandemics speaks for itself * Guardian *The world's most prominent virus hunter * New Yorker *The plague-ridden future imagined by this authoritative, measured, yet gripping book is extremely alarming * Sunday Times *A good place to start preparing for what might come * New Humanist *

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Book SynopsisTHE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world.The fully revised and updated 2018 edition codifies the U.S. government''s most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities Special considerations for neTrade Review[The CDC Yellow BooK 2018] is a truly excellent and comprehensive resource * Andrew Berrington, Journal of Hospital Infection *Table of ContentsList of Boxes, Figures, Maps, and Tables, by Topic List of Maps Editorial Staff CDC Contributors External Contributors Acknowledgments In Memoriam: Dedication to Alan J. Magill Preface 1. Introduction Introduction to Travel Health & the Yellow Book Planning for Healthy Travel: CDC Travelers' Health Website and Mobile Applications Travel Epidemiology Perspectives: The Role of the Traveler in Translocation of Disease Perspectives: Why Guidelines Differ Air Travel Trends 2. The Pre-Travel Consultation The Pre-travel Consultation Perspectives: Travelers' Perception of Risk Perspectives: Prioritizing Care for the Resource-Limited Traveler Perspectives: The Need for a Cost Analysis of to Justify the Travel MedicineConsult General Recommendations for Vaccination & Immunoprophylaxis Interactions among Travel Vaccines & Drugs Perspectives: Fear of Vaccines Self-Treatable Conditions Travelers' Diarrhea Perspectives: Antibiotics in Travelers' Diarrhea -- Balancing the Risks & Benefits For the Record: A History of the Definition & Management of Travelers' Diarrhea Altitude Illness For the Record: A History of the Definition & Management of Altitude Illness Jet Lag Motion Sickness Respiratory Infections Counseling & Advice for Travelers Food & Water Precautions Perspectives: Prevention of Travelers' Diarrhea-It's Not Only WHAT You Eat & Drink Water Disinfection for Travelers Food Poisoning from Marine Toxins Protection against Mosquitoes, Ticks, & Other Arthropods Sun Exposure Problems with Heat & Cold Injury Prevention Safety & Security Animal-Associated Hazards Natural Disasters Environmental Hazards Scuba Diving Medical Tourism Discussing Complementary and/or Alternative Integrative Health Approaches with Travelers Deep Vein Thrombosis & Pulmonary Embolism Mental Health Travel Health Kits Perspectives: Pharmaceutical Quality & Counterfeit Falsified Drugs Obtaining Health Care Abroad for the Ill Traveler Travel Insurance, Travel Health Insurance, & Medical Evacuation Insurance 3. Infectious Diseases Related to Travel Amebiasis Angiostrongyliasis, Neurologic Anthrax B virus Bartonella Infections Brucellosis Campylobacteriosis Chikungunya Cholera Coccidioidomycosis Cryptosporidiosis Cutaneous Larva Migrans Cyclosporiasis Cysticercosis Dengue Diphtheria Ebola Virus Disease and Marburg Virus Disease Echinococcosis Escherichia coli, Diarrheagenic Fascioliasis Filariasis, Lymphatic Giardiasis Hand, Foot, & Mouth Disease Helicobacter pylori Helminths, Soil-Transmitted Hepatitis A Hepatitis B Hepatitis C Hepatitis E Histoplasmosis HIV Infection Influenza Japanese Encephalitis Legionellosis (Legionnaires' Disease & Pontiac Fever) Leishmaniasis, Cutaneous Leishmaniasis, Visceral Leptospirosis Lyme Disease Malaria For the Record: A History of Malaria Chemoprophylaxis Measles (Rubeola) Melioidosis Meningococcal Disease Middle East Respiratory Syndrome (MERS) Mumps Norovirus Onchocerciasis (River Blindness) Pertussis Pinworm (Enterobiasis, Oxyuriasis, Threadworm) Plague (Bubonic, Pneumonic, Septicemic) Pneumococcal Disease Poliomyelitis For the Record: A History of Polio Eradication Efforts Q Fever Rabies Perspectives: Intradermal Rabies Preexposure Immunization Rickettsial (Spotted & Typhus Fevers) & Related Infections, including Anaplasmosis & Ehrlichiosis Rubella Salmonellosis (Nontyphoidal) Sarcocystosis Scabies Schistosomiasis Sexually Transmitted Diseases Perspectives: Sex & Tourism Shigellosis Smallpox & Other Orthopoxvirus-Associated Infections Strongyloidiasis Taeniasis Tetanus Tickborne Encephalitis Toxoplasmosis Trypanosomiasis, African (Sleeping Sickness) Trypanosomiasis, American (Chagas Disease) Tuberculosis Perspectives: Tuberculin Skin Testing of Travelers Typhoid & Paratyphoid Fever Varicella (Chickenpox) Viral Hemorrhagic Fevers Yellow Fever For the Record: A History of Yellow Fever Vaccine Requirements Yersiniosis Zika Virus Yellow Fever & Malaria Information, by Country 4. Select Destinations Rationale for Select Destinations Africa & The Middle East East Africa: Safaris Saudi Arabia: Hajj/Umrah Pilgrimage South Africa Tanzania: Kilimanjaro The Americas & The Caribbean Brazil Cuba Dominican Republic Haiti Mexico Peru: Cusco-, Machu Picchu, and Other Regions Asia Burma (Myanmar) Cambodia China India Nepal Thailand Vietnam The Middle East & North Africa Egypt & Nile River Cruises Saudi Arabia: Hajj Pilgrimage 5. Post-Travel Evaluation General Approach to the Returned Traveler Fever in Returned Travelers Persistent Travelers' Diarrhea Skin & Soft Tissue Infections in Returned Travelers Screening Asymptomatic Returned Travelers 6. Conveyance & Transportation Issues Air Travel Cruise Ship Travel Perspectives: What to Expect when Traveling during an International Outbreak Death during Travel Taking Animals & Animal Products across International Borders 7. International Travel with Infants & Children Traveling Safely with Infants & Children Vaccine Recommendations for Infants & Children Travel & Breastfeeding International Adoption 8. Advising Travelers with Specific Needs Immunocompromised Travelers Travelers with Chronic Illnesses Pregnant Travelers Travelers with Disabilities Immigrants Returning Home to Visit Friends & Relatives (VFRs) Health Care Workers Advice for Air Crews Humanitarian Aid Workers Long-Term Travelers & Expatriates Perspectives: Malaria in Long-Term Travelers & Expatriates Last-Minute Travelers Special Considerations for US Military Deployments Study Abroad & Other International Student Travel Travel to Mass Gatherings Newly Arrived Immigrants & Refugees Wilderness and Expedition Medicine Work-Related Travel Immunocompromised Travelers Appendices Appendix A: Promoting Quality in the Practice of Travel Medicine Appendix B: Travel Vaccine Summary Table Appendix C: Migrant Health Resources Index Photo credits

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Book SynopsisTuberculosis is characterized as a social disease and few have been more inextricably linked with human history. There is evidence from the archaeological record that Mycobacterium tuberculosis and its human hosts have been together for a very long time. The very mention of tuberculosis brings to mind romantic images of great literary figures pouring out their souls in creative works as their bodies were being decimated by consumption. It is a disease that at various times has had a certain glamour associated with it. From the medieval period to the modern day, Helen Bynum explores the history and development of tuberculosis throughout the world, touching on the various discoveries that have emerged about the disease over time, and focussing on the experimental approaches of Jean-Antoine Villemin (1827-92) and Robert Koch (1842-1910). Bynum also examines the place tuberculosis holds in the popular imagination and its role in various forms of the dramatic arts. The story of tuberculosisTrade ReviewThis is an ideal overview for the general reader that will also be of interest to historians. * Network Review, David Lorimer *Helen Bynum has written a book not only full of diverting asides but also of urgent importance. * Richard Horton, Guardian *Highly recommended. * M.L. Charleroy, CHOICE *Table of ContentsPrologue: George Orwell (1903-1950) ; 1. Ancient Bacteria, Old Diseases ; 2. All With 'A Touch of Consumption'? ; 3. Tubercles, Airs, Waters and Places ; 4. Consumption's Fashionistas ; 5. Consumption becomes Tuberculosis ; 6. Design for Living ; 7. Tuberculosis and the Health of the Race ; 8. Streptomycin & co ; 9. A Job Half Done ; Epilogue: 'There is no Dypraxa'

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Book SynopsisTrade Review"This book is easy to read, packed with a nice amount of useful information, and quite enjoyable.It focuses on many common conditions and syndromes that healthcare practitioners might encounter." -John S Czachor, MD (Wright State University Boonshoft School of Medicine) for Doody's Review ServiceTable of ContentsGraphic Guide to Infectious Disease Section 1. Viral Hepatitis 1.2. Hepatitis A 1.3. Hepatitis B 1.4. Hepatitis B-Serum Markers 1.5. Hepatitis C 1.6. Hepatitis D 1.7. Hepatitis E Section 2. Infectious Diarrhea 2.1. Bacterial 2.1.1. Shigellosis 2.1.2. Salmonellosis 2.1.3. Cholera 2.1.4. Campylobacteriosis 2.1.5. Enterohemorrhagic Escherichia Coli 2.1.6. Enterotoxigenic Escherichia Coli 2.1.7. Yersiniosis 2.1.8. Clostridium Difficile Infection 2.1.9. Vibriosis 2.2. Viral 2.2.1. Norovirus 2.2.2. Rotavirus 2.3. Protozoan 2.3.1. Giardiasis 2.3.2. Cryptosporidiosis 2.3.3. Amebiasis Section 3. Childhood Illness 3.1. Measles 3.2. Mumps 3.3. Rubella 3.4. Erythema Infectiousum 3.5. Examthum Subitum 3.6. Chickenpox 3.7. Congenital and Perinatal Infections 3.8. Pertussis 3.9. Hand, Foot, and Mouth Disease 3.10. Bronchiolitis 3.11. Kawasaki Disease 3.12. Croup Section 4. Tick Borne Illness 4.1Tick Borne Illness and Ticks as Vectors 4.2. Rocky Mountain Spotted Fever 4.3 Lyme Disease 4.4 Ehrlichiosis 4.5. Anaplasmosis 4.6. Babesiosis 4.7. Tularemia 4.8. Crimean-Congo Hemorrhagic Fever 4.9. Colorado Tick Fever Section 5. Worms 5.1. Roundworms 5.1.1. Ascariasis 5.1.2. Filariasis 5.1.3. Onchocerciasis 5.1.4. Pinworms 5.1.5. Hookworm 5.1.6. Whipworm 5.1.7. Trichinosis 5.1.8. Dracunculiasis 5.1.9. Cutaneous Larva Migrans 5.1.10. Threadworm 5.2. Tapeworms 5.2.1. Pork Tapeworm and Cysticercosis 5.2.2. Broad Fish Tapeworm 5.2.3. Beef Tapeworm 5.2.4. Dog Tapeworm 5.2.5. Dwarf Tapeworm 5.3 Flatworms 5.3.1. Schistosomiasis 5.3.2. Liver Fluke 5.3.3. Lung Fluke Section 6. Fungal 6.1. Sporotrichosis 6.2. Paracoccidiomycosis 6.3. Coccidiomycosis 6.4. Blastomycosis 6.5. Histoplasmosis 6.6. Tinea Infections of Skin 6.7. Tinea Versicolor 6.8. Aspergillosis 6.9. Mucormycosis Section 7. Sexually Transmitted Diseases 7.1. Gonorrhea 7.2. Condyloma Acuminata 7.3. Pubic Lice 7.4. Syphilis 7.5. Chlamydia 7.6. Trachoma 7.7. Reactive Arthritis 7.8. Herpes Simplex 7.9. Trichomoniasis 7.10. Scabies 7.11. Chancroid 7.12. Donovanosis 7.13. Vaginitis 7.14. Molluscum Contagiosum 7.15. Lymphogranuloma Venereum Section 8. Pulmonary 8.1. Middle Eastern Respiratory Syndrome 8.2. Tuberculosis 8.3. Legionnaires' Disease 8.4. Psittacosis 8.5. Avian Influenza 8.6. Influenza 8.7. Severe Acute Respiratory Syndrome Section 9. Mosquito Borne Illness 9.1. Zika Fever 9.2. Dengue 9.3. Yellow Fever 9.4. Malaria 9.5. Encephalitis 9.6. Chikungunya Section 10. Rat Borne Illness 10.1. Hanta Virus 10.1.1. Hemorrhagic Fever with Renal Syndrome 10.1.2. Hantavirus Pulmonary Syndrome 10.2. Plague 10.3. Leptospirosis 10.4. Rat Bite Fever 10.5. Trench Fever 10.6. Scrub Typhus 10.7. Epidemic Typhus 10.8. Endemic (Murine) Typhus 10.9. Arenaviridae Section 11. Oropharyngeal 11.1. Peritonsillar Abscess 11.2. Diphtheria 11.3. Herpangina 11.4. Thrush 11.5. Streptococcal Pharyngitis Section 12. Viral 12.1. Ebola 12.2. Rabies 12.3. AIDS: Opportunistic Infections 12.4. Smallpox 12.5. Mononucleosis 12.5. Polio Section 13. Parasites and Prions 13.1. Chagas Disease 13.2. African Sleeping Sickness 13.3. Pediculosis 13.4. Naegleriasis 13.5. Prion Diseases Section14. Bacterial 14.1. Anthrax 14.2. Botulism 14.3. Brucellosis 14.4. Typhoid Fever 14.5. Cat Scratch Fever 14.6. Leprosy 14.7. Infective Endocarditis 14.8. Tetanus 14.9. Listeriosis 14.10. Q Fever 14.11. Melioidosis

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Book SynopsisTable of Contents1. Vision Guiding Modernization of Global Health Security Section I International Regulatory Environment to Prevent, Detect, and Respond2. Ethics and Global Health Security3. National Interagency Collaboration for Public Health4. The imperative for global cooperation to prevent and control pandemics 5. International Legal Issues of National Sovereignty and Authority Impacting Global Health Security Section II Global One Health to Address Pandemics - Ecological and Biological Challenges in the Dynamic Planet6. (Re-)emerging Viral Zoonotic Diseases at the Human-Animal-Environment Interface7. EEmergence and Dissemination of Antimicrobial Resistance at the Interface of Humans, Animals, and the Environment8. Toxic and Environmentally Ubiquitous Chemical Agents9. Global Climate Change Impacts on Vector Ecology and Vector-borne Diseases10. Assessment of Critical Gaps in Prevention, Control, and Response to Major Bacterial, Viral, and Protozoal Infectious Diseases at the Human, Animal, and Environmental Interface11. Urbanization, Human Societies and Pandemic Preparedness and Mitigation Section III People and Goods on the Move12. The Interconnected World of Trade, Travel, and Transportation Networks13. Mitigating Negative Economic Impacts of Pandemics14. Health Measures at Points of Entry for Prevention15. Rights-based Global Health Security through all-hazard risk management Section IV Tools and Techniques to Modernize Prevention, Detection, and Response16. Global Laboratory Systems17. Modernizing Public Health Surveillance18. Creating One Health, Integrated, and Informatics-Savvy Health Organizations 19. Analytics and Intelligence for Public Health Surveillance20. Tools and Techniques for Modernizing Prevention, Detection, and Response 21. Countering Vaccine Hesitancy Section V Moving to the Best-protected Global Community22. Science and Political Leadership in Global Health Security23. Influence of Finance and Philanthropy24. Enhancing Trust and Transparency in Public Health Programs25. Workforce Development26. Advancing Conceptual and Practical Links between Health System Preparedness and Long-term Benefits to Achieve Health Security 27. Measuring Progress of Public Health Response and Preparedness

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Book SynopsisIn The Top Ten Diseases of All Time, Stacey Smith? presents the top ten deadliest diseases and their effects on society, providing a wealth of information about the trajectory and terrible impact of each disease, and humanity's reaction to these diseases throughout the millennia.Table of ContentsTable of ContentsPrefaceChapter 10: The Third PlagueChapter 9: CocoliztliChapter 8: HIV/AIDSChapter 7: Justinianic PlagueChapter 6: Spanish FluChapter 5: Black DeathChapter 4: MeaslesChapter 3: SmallpoxChapter 2: TuberculosisChapter 1: Well, that Would be TellingLessons Learned and the Way ForwardFurther ReadingAbout the Author

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Book SynopsisIn this book Michaela Gloeckler gives new inspiring perspectives on the significant role of the human heart in the development of the immune system, from early embryological growth through to adulthood. She explains the importance this has for an understanding not only of immunity but also conscience and common sense, hence also of the Covid crisi

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Book SynopsisIn the past years, COVID-19 caused millions of deaths and severely damaged not only public health, but also the global economy. New variants continue to threaten human health. Thus, natural compounds for retarding infection are in high demand. This book summarizes the emerging research with flavonoids, whose application holds great promise of antivirus, anti-inflammation, antioxidative stress, and immunomodulatory. Topics include the role of flavonoids in preventing an inflammatory storm and how flavonoids interact with critical protein targets that are involved in the infection stages of COVID-19.Key Features Highlights anti-SARS-CoV-2 drug discovery on natural products and medicinal plants Includes all major subclasses of flavonoids that promisingly combat COVID-19  Proposes molecular mechanisms of flavonoids against protein targets of SARS-CoV-2 Contributions from an international team of leading researchers Provides recommendations

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