Surgical oncology Books

Book SynopsisSelected as a Doody’s Core Title for 2023! Now with additional review content and a larger page size, The MD Anderson Surgical Oncology Manual, Seventh Edition, focuses on multidisciplinary, cooperative management approaches to issues confronting today’s surgical oncologist. Lead editor Dr. Barry W. Feig is joined by recently graduated surgical oncology fellows Michael G. White, Cameron E. Gaskill, Anai N. Kothari, and Sandra R. DiBrito to bring you comprehensive yet concise information on the complete range of oncologic considerations needed to effectively understand cancer and all aspects of its treatment. Walks you through epidemiology and etiology, pathology, staging, clinical presentation and diagnosis, surgical treatment, and adjuvant therapies for each disease site or system Includes new case studies with multiple choice review questions at the end of each chapter Features a new, larger page size, up-to-date information on the latest staging and protocols, and well-written, easy-to-read content throughout Written by current and former MD Anderson surgical oncology fellows Ideal for fellows in surgical oncology, general surgery residents, medical students facing a surgical/oncology rotation, and practicing surgeons Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

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Book SynopsisNow fully revised and in its fourth edition, the Oxford Handbook of Oncology has been the essential go-to guide for students and practitioners in oncology for over a decade. The scientific basis and diagnosis of cancers is covered, as well as drugs, biomarkers, and the presentation and psychosocial aspects of oncology. Concise, practical, and comprehensive, there is no better companion for both common conditions and challenging emergencies.The field of oncology has surged forward since the last edition was published and the Oxford Handbook of Oncology has been fully revised and updated to reflect these recent advances so you can be sure that the vital information you need is in your hands. This handbook incorporates changes such as the understanding of the science of cancer, novel therapies in breast, lung, renal, and melanoma, molecular sub-classification of common solid cancers, personalized therapy approaches, new agents in hard to treat cancers, the benefits of new technologies in Trade ReviewWritten by experts in the field to ensure that it is grounded in real life clinical practice, this Handbook provides a concise guide to all aspects of oncology for all students, nurses, and junior faculty responsible for the care of cancer patients, while also providing further reading and highlighting areas of controversy for those who need a more detailed understanding. * Anticancer Research *Table of Contents1. Multidisciplinary approach to cancer ; 2. Aetiology and epidemiology ; 3. Genetics of cancer ; 4. Surgical oncology ; 5. Principles of radiation oncology ; 6. Principles of chemotherapy ; 7. Principles of symptom control in palliative care ; 8. Late effects of radiotherapy and chemotherapy ; 9. Hormone therapy ; 10. Biological and targeted therapies ; 11. Clinical trials ; 12. Cancer prevention ; 13. Population screening for cancer ; 14. Thoracic cancer ; 15. Breast cancer ; 16. Colorectal cancer ; 17. Anal cancer ; 18. Upper gastrointestinal cancer ; 19. Endocrine cancers ; 20. Genitourinary cancers ; 21. Gynaecological cancer ; 22. Head and neck cancer ; 23. Tumours of the central nervous system ; 24. Skin cancer ; 25. Haematological malignancies ; 26. Bone and soft tissue malignancies ; 27. Cancer of unknown primary site ; 28. Paraneoplastic syndromes ; 29. AIDS-related malignancies ; 30. Childhood cancers presenting in adulthood ; 31. Overview of Acute Oncology ; 32. Spinal cord compression and bone marrow suppression ; 33. Superior vena cava obstruction and raised intracranial pressure ; 34. Stridor ; 35. Thromboembolic and cardiac emergencies ; 36. Obstruction ; 37. Biochemical crises ; 38. Complications of long-term central venous lines and chemotherapy extravasation ; 39. Novel therapeutic strategies ; 40. Gene therapy and immunotherapy for cancer ; 41. Biomarkers and Cancer ; Appendices

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Book SynopsisTable of ContentsIntroduction A- Basics of breast diffusion MRI - General principles and challenges of diffusion MRI (Le Bihan, Iima, Partridge) This section will provide the physical basis of Diffusion MRI, give the key concepts necessary to understand and use DWI in clinical practice B- Breast Clinical Applications - Overview of conventional breast imaging (MMG, US, MRI except DWI) (Mann and/or Kuhl) This chapter will give a general overview of the field of breast imaging, with pros and cons, to help positioning DWI among all other approaches - Overview of breast DWI: Diagnosis of suspicious lesions using DWI in combination with standard MRI (20 pages) (Baltzer, Clauser, Gilbert) This chapter will review how DWI is currently used as a breast imaging modality and how breast lesions appear with DWI - Biomarkers, prognosis and prediction factors (10 pages) (Iima, Moy) This chapter will explain how DWI could be specifically used to provide information on prognosis and prediction factors (eg Her, Pg, ER, Ki67 receptors expression) and help lesion management - Disease and treatment monitoring (10 pages) (Partridge, Hylton, Li) This chapter will provide guidance on how DWI can be used to manage breast lesions, from diagnosis to treatment monitoring, using examples for most common types of lesions - Diffusion MRI as a stand-alone unenhanced breast imaging approach and screening (10 pages) (Amornsiripanitch, Hee Jung Shin, Partridge) This chapter will foresee how DWI could be used as a stand-alone approach (without DCE): patient population, technical requirement - DWI and breast physiology status (menstrual cycle, pregnancy, lactation) (10 pages) (Iima, Nissan) This chapter will review how changes in hormonal context and physiology may affect appearance of DWI normal breast tissues and lesions C- Challenges and Advanced Techniques - IVIM/perfusion Non-Gaussian diffusion (20 pages) (Sigmund, Iima, Le Bihan) This chapter will show how tissue microcirculation (perfusion) can be obtained from DWI without the need for tracers or contrast agent, explain why boosting sensitivity to diffusion provides added contrast and information on tissue microstructure, and how to combine both approaches in a clinical setting - DTI (20 pages) (Sigmund, Partridge) This chapter will explain how Diffusion Tensor Imaging could potentially reveal oriented features in the breast (eg ducts) and how lesions might modify them - Tissue characterization, radiomics, Artificial Intelligence, multiparametric imaging and integration of diffusion MRI to BIRADS (20 pages) (Pinker, Morris) This chapter will explain how DWI could be combined to other advanced breast imaging approaches to provide higher sensitivity, specificity and prognosis - Novel/Alternative Acquisition Techniques - (20 pages) o DWIBS (Takahara) o MS-EPI, RS-EPI, SMS, RSI, etc - (Hargreaves) Those short chapters will provide glances at novel or alternative methods to perform DWI with specific focus for breast applications D- Let us get practical - Clinical interpretation of diffusion MRI, ROI assessment, common errors, pitfalls and artifacts, challenges in acquisition (20 pages) (Gilbert, Patterson) This chapter will provide guidance on the interpretation of DWI in the breast, qualitatively and quantitatively, showing how common errors can be avoided and artifacts corrected - Quality control, standardization, test-objects (20 pages) (Chenevert, Newitt, Malyarenko, Keenan) This chapter will provide guidance on how to optimize DWI protocols, verify and control settings to obtain accurate and reproducible results

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Book SynopsisThis acclaimed text continues to focus on the essential techniques for effective surgical management of patients with ovarian cancer and related peritoneal surface malignancies. With a wealth of accompanying illustrations and operative videos; this fourth edition reflects the evolution - and controversies - in the use of minimally invasive and robotic surgery and the introduction of HIPEC treatment options.Trade Review"...amply meets its goals and fulfills a need for a comprehensive text."- Doody's Review Service"The updates in this fourth edition of a classic textbook amply justify its publication. The book has been thoroughly revised throughout, and several topics have been expanded."- Carol Scott-Conner, MD, PhD, MBA, University of Iowa Hospitals and ClinicsTable of Contents1. Historical development of cytoreductive surgery for ovarian cancer and scientific update.2. Epidemiology, staging, and clinical characteristics. 3. Preoperative risk stratification and intraoperative supportive care.4. Instrumentation, retractors, ablative technologies and techniques, set-up and conduct of operation.5. Management of Early-Stage Ovarian Cancer.6. Cytoreductive surgery: Principles and rationale. 7. Predicting Surgical Outcome: Patient Selection for Initial Surgery or Chemotherapy. 8. Cytoreductive Surgery: Pelvis and Radical Oophorectomy. 9. Cytoreductive surgery: Abdominal retroperitoneum and adenopathy. 10. Cytoreductive surgery: Intestinal tract and Omentum.11. Cytoreductive surgery: Right upper abdomen—Diaphragm. 12. Cytoreductive surgery: Right upper abdomen—Liver, gallbladder, and porta hepatis. 13. Cytoreductive surgery: Left upper quadrant. 14. Peritonectomy procedures for ovarian cancer. 15. Regional Therapeutics and Peritonectomy Procedures for Ovarian Cancer. Robert DeBernardo. 16. Secondary cytoreductive surgery. 17. Minimally Invasive Surgery in Ovarian Cancer. 18. Palliative surgery for ovarian cancer. 19. Postoperative management. 20. Quality indicators for ovarian cancer surgery. 21. Ovarian Cancer Surgery in Low Resource Settings: Global Health Program Development Infrastructure.

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Book SynopsisThis is the only reference and textbook of its kind to cover perioperative and supportive care in gynecologic oncology within the framework of evidence-based medicine.Table of ContentsForeword to the Second Edition ix Contributors xi Part One General Principles 1. Introduction 1 Steven A. Vasilev and Scott E. Lentz 2. Evidence-Based Medicine and Decision Support 11 Steven A. Vasilev 3. Vascular Access and Other Invasive Procedures 43 Paul Koonings and Scott E. Lentz 4. Fluids, Electrolytes, and Nutrition 69 Howard Silberman and Matthew Powers Part Two Perioperative Management of Gynecologic Surgery 5. Preoperative Evaluation 145 Devansu Tewari 6. Postoperative Surveillance and Perioperative Prophylaxis 161 Harriet O. Smith and Lejla Delic 7. Perioperative Infections: Prevention and Therapeutic Options 235 Amy Stenson 8. Intraoperative and Perioperative Considerations in Laparoscopy 261 Steven A. Vasilev and Scott E. Lentz Part Three Oncologic Perioperative Decision Making 9. Cervical Carcinoma 299 Fidel A. Valea 10. Endometrial Cancer 329 R. Wendel Naumann 11. Pelvic Masses and Ovarian Carcinoma 361 Margarett C. Ellison 12. Molar Gestation 377 Allison E. Axtell and Steven A. Vasilev 13. Perioperative Issues in the Management of Vulvar Cancer 389 Kathryn F. McGonigle and Maliaka W. Amneus Part Four Complimentary Medicine/Supportive Care 14. Perioperative Psychosocial Considerations 419 Judith McKay and Steven A. Vasilev 15. Pain Management in Gynecologic Oncology 443 Laszlo Z. Galffy and Clayton A. Varga 16. Fertility Preservation in the Gynecologic Cancer Patient 469 Nicole Fleming 17. Perioperative Herbal and Supplement Use 487 Alexander Vasilev and Steven Vasilev 18. End-of-Life Decision Making 509 Scott E. Lentz Index 539

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Book SynopsisOne in two of us will develop cancer at some point in our lives and yet many of us don''t understand how cancers arise. How many different kinds of cancer are there? What treatments are available? What does the future hold in terms of developing new therapies? This book demystifies cancer by explaining the underlying cell and molecular biology in a clear and accessible style. It answers the questions commonly asked about cancer such as what causes cancer and how cancer develops. It explains how DNA makes proteins and how mutations can corrupt those proteins. It also gives an overview of current therapies and how treatments may advance over the next decades, as well as explaining what actions we can take to help prevent cancer developing. Understanding Cancer is an accessible and engaging introduction to cancer biology for any interested reader.Trade Review'How often have we attended a lecture or opened a book to find that within minutes we are smothered by complicated facts that are way beyond our understanding? There has been no simple introduction. The speaker/author is so involved in the topic that they could no longer see out of the intellectual hole that they had dug for themselves. If ever a book was written to dispel this fault, then this is the one, as Robin Hesketh has managed to provide a remarkably clear and readable account of the science behind cellular behaviour and faults that lead to the development of cancer. The book reads like a novel, and I found that I could hardly put it down. The literary style is at times light-hearted with humorous analogies.' Robert Whitaker, anatomist, University of Cambridge'Understanding Cancer presents a carefully crafted, clear and concise book on aspects of cancer; a disease of importance to us all. Most readers will come to Robin Hesketh's book with questions about cancer. Understanding Cancer will not disappoint. The most usual questions and answers are presented in the first chapter and ways of reducing the risk of some cancers are suggested later. This book puts cancer into a historical and very interesting context; it then explores cancer, its biochemistry and functioning in an approachable way. Information is given about the latest treatments and the science behind them. This very readable book contains something for everyone. It is positioned, and very adequately fills, the gap between personal accounts by patients of their experiences, and more advanced medical and cell biology texts. Understanding Cancer is well researched and greatly recommended.' David Archer, schools liaison officer, British Society for Cell Biology'Understanding Cancer is a fascinating and engaging perspective on the evolution of cancer research and treatment. Dr Hesketh provides insight into the key clinicians and scientists, following their discoveries in clinical care and research. He overviews the likely mutagenic causes of cancer spurring on the oncogenic transitions leading to a cancer cell that can replicate uncontrollably, highlights new avenues in cancer research, and conveys that preventive measures and advances in early cancer detection could make an impact on cancer incidence and patient outcomes/survival. This book is certainly a triumph and a must-read for all current and future scientists, physicians at any stage of their professional careers and anyone interested in cancer research and the quest for effective anti-cancer treatments.' David Lyden, David Lyden, cancer researcher and paediatric oncologist, Weill Cornell Medicine, Cornell UniversityTable of Contents1. Painting a clear picture; 2. Ancient history; 3. Counting cancer; 4. From DNA to protein; 5. What is a cell?; 6. Mutations; 7. Causes of cancer that can be controlled; 8. Causes of cancer that are difficult to control, accidents … and other things; 9. Treating cancer by chemotherapy; 10. The road to utopia?

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Book SynopsisA concise summary of the most important clinical trials in cardiac and thoracic surgery. The focus is on how evidence-based decision making has helped to shape modern practice and guidelines. The key trials are described and an overview of their impact provided.Much research has been undertaken to study the efficacy of different drugs, techniques, and treatment strategies within cardiothoracic surgery. As a result, many randomised controlled trials have been published which discuss a wide variety of topics and with the intention of improving current practice and patient care. This volume presents a selection of the key trials and assesses their impact. Compact and easy to read, the distillation of core information will enable the reader to understand the importance of the key papers that have influenced best practice across operating theatres, clinics, multi-disciplinary meetings, and inpatient management.Including full summaries of more than 30 trials and reflecting tTable of ContentsPreface. Acknowledgment. Contributors. THORACIC CHAPTERS. Lung Cancer Screening. Surgical Approach. Resection of Lung Cancer: Lobectomy vs. Sublobar Resection. Lung Cancer Surveillance after Definitive Treatment. Management of Primary Spontaneous Pneumothorax. Thymectomy in Non-Thymomatous Myasthenia Gravis. Surgical Treatment of Mesothelioma. Rib Fixation in Rib Fractures. Treatment of Advanced Emphysema. Surgery vs. SABR in Operable Stage I Lung Cancer. Pulmonary Metastasectomy in Colorectal Cancer. Role of Targeted Therapy In Resectable Lung Cancer. Role of Immunotherapy in Lung Cancer Treatment. Management of Prolonged Air Leak. CARDIAC CHAPTERS. On-Pump vs. Off-Pump CABG. TAVI vs. Standard Approach. Surgery in Ischaemic Mitral Valve Regurgitation. Radial Artery Graft Patency. Surgical Prevention of Stroke during Cardiac Surgery in Patients with Atrial Fibrillation. Surgical Treatment of Asymptomatic Severe Aortic Stenosis. Restrictive vs. Liberal Red-Cell Transfusion for Cardiac Surgery. Multivessel Revascularisation in Patients with Diabetes. Early Surgery vs. Conventional Treatment for Infective Endocarditis. LIMA Alone vs. LIMA and RIMA. Percutaneous Coronary Intervention (PCI) vs. Coronary artery bypass graft (CABG). Index.

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Book Synopsis Achieve the best outcomes with expert, practical, highly visual guidance! Operative Techniques in Foregut Surgery features just the foregut surgery content from Operative Techniques in Surgery, the comprehensive 2-volume set edited by Michael W. Mulholland, MD, PhD. Ideal for practitioners who wish to focus on mastering today’s best foregut surgery procedures, it you step-by-step through each technique in a consistent manner, using concise, bulleted text, full-color illustrations, and full-color intraoperative photographs to clearly convey exactly what to look for and how to proceed.Key Features Master the full range of essential procedures with comprehensive coverage of paraesophageal hernia surgery, GERD treatment of esophageal cancer and esophageal perforation, surgery of the stomach and duodenum, bariatric operations, and surgery of the gall bladder, spleen, and abdominal wall. Select the best open or minimallTrade Review'a worthwhile purchase for the aspiring foregut surgeon''perioperative work-up , patient positioning , and key operative steps are immensely valuable to surgeons in training''covers most every operation that occurs in the foregut''emphasizes both figures and crisp operative images to convey the information rather than relying heavily on text'Weighted Numerical Score: 83 - 3 Stars-Doodys Publishers' Club, June 19, 2015

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Book SynopsisThe second edition of Endocrine Surgery is a comprehensive update of the previous edition published in 2003. Edited by three leading authorities in the field of surgical endocrinology, the book encompasses the clinical, imaging, nuclear, molecular, technological and evidence-based principles that are applied in the diagnosis and treatment of all categories of endocrine tumors. Authored by experts from across the globe, this textbook reflects the best international clinical practice and also provides an outstanding educational resource. With full color illustrations throughout, the new edition emphasizes contemporary approaches in successive stages including: pituitary endocrine tumors; pathology and pathophysiology of pulmonary neuroendocrine cells; surgery of endocrine tumors of the lungs and thymus; robotic endocrine surgery; molecular testing of thyroid nodules; pediatric surgery for neuroblastoma and ganglioneuroma; multiple endocrine neoplasia; retroperitoneoscopiTable of ContentsIntroduction.Molecular Endocrinology.Robotic Endocrine Surgery.Brain, Lung and Thymus.The Endocrine Brain.Selective Sampling of Petrosal Veins.Pituitary Tumors.The Endocrine Lung and Thymus.Broncho-Pulmonary and Thymic Carcinoids, Other Endocrine Tumors.Pulmonary Endocrine Pathology.Thyroid.Thyroid Physiology.Cytology and Surgical Pathology.Thyroid Imaging: Ultrasound, Thyroid Imaging: Radionuclide.Intrathoracic Goiter.Hyperthyroidism.Thyroid Nodules.Molecular Testing of Thyroid Nodules.Well Differentiated Thyroid Cancer Surgery.Medullary Thyroid Carcinoma.Anaplastic Cancer-Pathology.Endoscopic + Robotic Thyroidectomy.Video-Assisted Thyroidectomy.Principles of Thyroid Surgery and Outcomes.Parathyroid.Presentation of Hyperparathyroidism.Imaging of Parathyroids:.Imaging 4D CT Scanning.Surgery for Hyperparathyroidism.Reoperation for Hyperparathyroidism.Parathyroid Carcinoma.Adrenals.Adrenocortical Function, Adrenal Insufficiency.Pathology of Adrenal Tumors.Imaging: CT, MRI, PET Scans.Radionuclear Imaging.Adrenal Vein Sampling For Diagnosis and Localization Of Aldosteronoma And Cushing's Adenoma.Cushing's Syndromes, Cortical Carcinoma, Estrogen and Androgen Secreting Tumors.Primary Aldosteronism.Neuroblastoma and Ganglioneuroma.Pheochromocytoma.Adrenal Incidentaloma.Laparoscopic Adrenalectomy.Techniques of Adrenalectomy.Pancreas.Pathology of the Endocrine Pancreas.Imaging of the Pancreas CT, MRI, PET.Radionuclide Imaging of Pancreas.Insulinoma.Hyperinsulinism (Nesidioblastosis) in Newborns.Gastrinoma (Zollinger-Ellison Syndrome) and Rare Neuroendocrine Tumors.Pancreatectomy Traditional.Laparoscopic Pancreatectomy.Inherited Syndromes.Multiple Endocrine Neoplasia and Other Familial Endocrine Tumor Syndromes.Gastro-Entero-Pancreatic System.Carcinoid Tumors.Serotonin-Induced Cardiac Valvular Disease and Pulmonary Hypertension.Endocrine Tumors of the Gastrointestinal Tract.Multimodality Management of Primary and Metastatic Neuroendocrine Tumors.Cytoreduction.Liver Transplantation for Neuroendocrine Tumors.Medical Management.Metabolic Surgery.Pathophysiology and Surgery if Type II Diabetes.Post-Bariatric Surgery, Non-Pancreatogenous Hyperinsulinemic Hypoglycemia.Surgical Management of Metabolic Syndrome.Gut Peptides

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Book SynopsisWeaving the personal story of an oncologist dealing with his father's terminal cancer with stories inspired by encounters in his practice, Cancer Confidential uncovers the emotional responses of people living with cancer and those who care for them.Table of ContentsDisclaimer Prologue: Medicine as Theatre 1. The Medical Son 2. The Reticent Doctor 3. The Scared Patient 4. The Puppeteer Doctor 5. The Disobedient Patient 6. The Ornery Surgeon 7. The Confused Patient 8. The Interfering Child I 9. The Pushy Patient 10. The Fractured Family 11. The Failed Patient 12. The Shunned Patient 13. The Brave Patient 14. The Interfering Child II 15. The Desperate Couple 16. The Dying Father Epilogue: The Authentic Doctor Acknowledgments

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Book Synopsis Selected as a Doody's Core Title for 2022 and 2023! Fourth in a new four-volume series, Operative Techniques in Gynecologic Surgery: Gynecologic Oncology provides superbly illustrated, authoritative guidance on operative techniques along with a thorough understanding of how to select the best procedure, how to avoid complications, and what outcomes to expect. Easy to follow, up to date, and highly visual, this step-by-step reference covers the most common operations in gynecology and is ideal for residents and physicians in daily practice. Succinct text, bulleted points, and quick-reference tables allow you to review information quickly and understand best practices and potential problems for each procedure. Forty two videos of 56 operations performed by 14 international experts show in detail  how to perform the procedures step by step and help you immediately apply your knowledge. This is supplemented by illustrations and int

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Book SynopsisGastric cancer is the fourth most common cancer in the world. Most gastric cancers are diagnosed in advanced stages, and the prognosis remains poor. The 5-year survival rate is 40-60% in eastern countries and around 25% in the west. Among advanced gastric cancer cases, peritoneal implantation is one of the most common forms of metastasis and around 14% of cases present peritoneal metastases at initial diagnosis, presenting a survival of 3-6 months. Until the early 1990s it was considered a terminal disease. But today these patients have some opportunities to be treated with curative intent or to prolong their life. Although the prognosis remains poor, there are some treatment options including cytoreductive surgery, neoadjuvant therapy, and some forms of intraperitoneal chemotherapy with or without hyperthermia. These are aggressive treatments, so we must be careful when selecting patients. Imaging and preoperative staging are also crucial in selecting patients for appropriate treatment. The surgical technique is described and a detailed demonstration video is available in the e-book version. New forms of treatment such as PIPAC and new scientific advances and future perspectives are discussed. This book is an update on this topic and attempts to provide an overview for all medical personnel involved in the treatment of these patients.Table of ContentsPreface; Epidemiology of gastric cancer; Role of imaging in peritoneal surface malignancies; Diagnosis and staging in advanced gastric cancer; Histopathological and molecular classifications of gastric cancer; Patient selection and preoperative considerations; Neoadjuvant and adjuvant therapy; Principles of cytoreductive surgery; Role of intraperitoneal chemotherapy.; Current role of PIPAC in peritoneal metastases of gastric origin; Scientific Advances and future perspectives; Index.

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Book SynopsisBone tumours are very rare, accounting for less than 0.2% of all cancers. As our understanding of these tumours at the molecular level is improving, as well as recent advances in imaging and treatments, there is an obvious need for an update in this field. This comprehensive book is the result of the contribution of different internationally renowned expert teams in the management of bone tumours and particularly spinal neoplasms. The first five chapters deal with spinal tumours, either primary or metastatic, giving the reader a clear clinical review of the disease and its pathophysiology, as well as therapeutic options. The following chapters are dedicated to new insights in the medical treatment of bone tumours, an overview on the mechanism of malignant transformation of benign bone tumours, the modern management of pain in bone metastases, and the modern therapeutics of bone tumours in prostate cancer patients.

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Book SynopsisA focused guide from the world's experts on metastatic spine tumors" This first volume in the AOSpine Masters Series integrates the expertise of oncologists and radiology interventionalists with that of master spine surgeons, all of whom are actively involved in the care of patients with metastatic spine tumors. The book provides expert guidance to help clinicians make the right treatment decisions and provide the best care for their patients. Chapter topics range from evaluation and decision-making principles to a spectrum of non-operative and operative treatment options that have been rapidly evolving over the past decade. Key Features: Editors are internationally-recognized authorities on metastatic spine tumors Includes contributions from key opinion leaders working in spine oncology Synthesizes the best available evidence and consensus expert advice on metastatic spine tumors, leading to optimal clinical recommendations Each chapter includes clinical pearls, tips on complication avoidance, and "top 5 must-read references" The AOSpine Masters Series, a co-publication of Thieme and the AOSpine Foundation, addresses current clinical issues whereby international masters of spine share their expertise and recommendations on a particular topic. The goal of the series is to contribute to an evolving, dynamic model of an evidence-based medicine approach to spine care. All neurosurgeons, orthopedic surgeons, neuro-oncologists, and orthopedic oncologists specializing in spine, along with residents and fellows in these areas, will find this book to be an excellent guide that they will consult often in their treatment of patients with metastatic spine tumors. Table of Contents1 Evaluation and Decision Making for Metastatic Spinal Tumors 2 Neoplastic Spinal Instability 3 Major Complications Associated with Stereotactic Ablative Radiotherapy for Spinal Metastasis 4 En Bloc Resection in the Treatment of Spinal Metastases: Technique and Indications 5 Region-Specific Approaches 6 Spinal Reconstruction and Fixation/Fusion 7 Minimally Invasive Surgery for Metastatic Spine Disease 8 Vertebral Augmentation for Metastatic Disease 9 Surgical Complications and Their Avoidance

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Book SynopsisRenal Cancer: Current Status and Innovations provides a useful guide to the fundamental basics and latest diagnostic and treatment techniques for Renal Cancer. It features clearly structured and easy-to-understand chapters enabling the reader to develop a thorough understanding of screening, surveillance, diagnostics, pathology, robotic and open surgical approaches, ablation, medical treatment, psychology, and future innovations. The book provides a valuable resource for the full spectrum of clinicians involved in the multidisciplinary management of Renal Cancer.Table of ContentsIntroduction to the Multidisciplinary approach to Renal Cancer.- Imaging in Renal Cancer.- Application of Simulation Techniques.- Cognitive Simulation & Non technical skills training.- Team training.- Active surveillance and Percutaneous Treatment.- Endoscopic Surgery.- Laparoscopic Renal Surgery.- Robotic Surgery.- Focal Therapies.- Pre and Post-surgery, treatments.- Big Data and Renal Outcomes.- Future perspectives.

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Book SynopsisOver the last several decades breast cancer management has made great strides in the improvement of oncologic treatment outcomes, particularly so in patients with early stage disease. While wide-spread access to screening resulting in early detection is undoubtedly to be credited for this trend, at the same time, the management of breast cancer has evolved to be an intricate multidisciplinary collaboration between breast imagers, surgeons, medical oncologists and radiation oncologist. As a result, with better mutual understanding of multidisplinary goals and challenges, the treatment strategies have become more individualized, with a great emphasis being placed on the intrinsic disease biology. Furthermore, the indications for neoadjuvant systemic therapy have significantly broadened, with a substantial number of patients with early stage breast cancer being able to take advantage of this strategy to decrease the extent of breast surgery they would undergo at its completion. As such, the management of the axilla in these patients has presented with new challenges as well as with new opportunities to scale down on the extent of local therapy and, consequently, its toxicity.This text will provide a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians (surgeons, medical oncologists, radiation oncologists) and researchers with an interest in breast cancer. The book will review novel and evoling strategies in neoadjuvant systemic therapy forn early stage breast cancer, provide new perspectives about appropriate axillary imaging in anticipation of neoadjuvant systemic therapy, and describe new data on innovative surgical techniques and Radiation Oncology concepts designed to deescalate the extent and toxicity of local therapy while insuring oncologic safety. Several landmark clinical trials have been published in the last few years and will be placed in context with respect to current management. Integration of novel diagnostic and interventional breast imaging, local therapy (surgery and radiation) with contemporary systemic therapy will also be discussed. This text will serve as a very useful resource for physicians and researchers dealing with, and interested in, this challenging field. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.Table of ContentsEvolution of the indications for neoadjuvant systemic therapy.- Defining response.- Imaging of the breast.- Imaging of the axilla and approach to node-negative vs. node-positive disease at presentation.- Guidelines for imaging during neoadjuvant systemic therapy.- Neoadjuvant systemic therapy based on the underlying tumor biology.- Adjuvant vs. neoadjuvant systemic therapy.- Molecular testing and personalized neoadjuvant treatment.- Pre-and post-neoadjuvant systemic therapy imaging assessment.- Surgical management of the axilla in node-negative and node-positive disease at diagnosis.- Surgical considerations and expectations in patients receiving neoadjuvant hormonal therapy and neoadjuvant chemotherapy.- Postmastectomy radiation considerations in patients receiving neoadjuvant chemotherapy.- Pathologic evaluation in neoadjuvant systemic therapy setting.- Guidelines for Neoadjuvant systemic therapy.- Ongoing Clinical studies and future direction.

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Book SynopsisThis latest book in the Management of Urology Series provides insight into how to appropriately manage patients undergoing pelvic robotic urological surgery for renal cancer. Extensive guidance is provided on how to perform a range of procedures including the retroperitoneal renal approach along with information on how to utilize the latest robots effectively. Cases are also presented on how to best manage complications associated with partial nephrectomy. Each chapter also contains learning objectives to assist the reader in extrapolating the key information covered.Robotic Surgery for Renal Cancer is an up-to-date overview of the latest techniques utilized in this field along with potential management strategies for these patients, making it a critical resource for urologists, oncologists, and specialist nurses.Table of ContentsSuturing techniques in robot-assisted partial nephrectomy (RAPN).- Resection techniques robotic-assisted partial nephrectomy.- Clamping techniques for partial nephrectomy.- Robotic retroperitoneal partial nephrectomy.- Robotic partial nephrectomy.- Pushing the boundaries in robot-assisted partial nephrectomy for renal cancer.- Perioperative surgical complications in robotic partial nephrectomy.- Renal robotic surgery for lefties - Left-handedness in upper tract robotic surgery.- Training with new robots and how to transition from one system to the next in renal cancer surgery.- New robots and how this has changed operative technique in renal cancer surgery.- Use of indocyanine green (ICG) during robotic surgery for renal cancer.- 3D virtual models and augmented reality for robot-assisted partial nephrectomy.- Open partial nephrectomy: Current status in the minimally-invasive surgery era.- Decision-making for patients with localized renal masses.- Management of localized renal masses: The European Association of Urology (EAU), American Urological Association (AUA) and American Society of Clinical Oncology (ASCO) guidelines’ perspective.- Active surveillance and watchful waiting in renal cancer.- Ablative therapies in renal cancer.- Open radical nephrectomy.- Robotic surgery for renal cancer: Transperitoneal and retroperitoneal port placement.- Robot assisted laparoscopy for renal cancer: Transperitoneal vs retroperitoneal approach.- Robotic radical nephrectomy.- Preoperative set-up of patients undergoing robotic inferior vena cava thrombectomy.- Renal cell carcinoma with tumour thrombus: A review of relevant anatomy and surgical techniques for the general urologist.- Cytoreductive nephrectomy in metastatic renal cell carcinoma.

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Book SynopsisThis book will offer a practical guide for the surgical management of oncologic emergencies, that pose great challenges to both surgeons and oncologists. Combining the knowledge of experienced surgeons and oncologists, it describes the experience gained from daily life into a tertiary hospital. Every chapter will be focused on radical treatment of primary tumors, metastatic disease and palliation, and will include an “Highlight” section with 4-5 key messages at the beginning of each chapter, whereas at the end a flow-diagram will be employed to summarize the subject discussed topic. Every chapter will be written by at least two authors, including a surgeon and an oncologist, to guarantee a 360 degrees analysis of each topic. This work will benefit both surgeons and oncologists: surgeons will found in it a step to step practical tool that helps the decision making process, while oncologists will find interesting indications about how and when to involve a general surgeon into the management of an oncologic emergent condition.Table of ContentsHead and neck.- Adrenal glands.- Lung.- Esophagus.- Stomach.- Duodenum.- Small Bowel.- Right colon.- Appendix.- Left colon.- Rectum.- Liver.- Pancreas.- Gallbladder and biliary tract.- Spleen.- Uterus and Ovaries.- Kidney.- Urinary Bladder.- Peritoneal carcinosis.- Miscellaneous rare malignancies - Intra-abdominal lymphomas.- Miscellaneous rare malignancies – GIST.- Miscellaneous rare malignancies – Desmoplastic.- Miscellaneous rare malignancies – Sarcomas.- Miscellaneous rare malignancies - Pseudomixoma peritoneum.- Ethical issues.

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Book SynopsisThis book is a revision companion for the UEMS breast exam. The contents extract and distil the key messages and facts of the exam-linked textbook, published in 2017, giving self-test opportunities in the last chapter. Each chapter starts by listing the key facts. The chapters have been edited by the exam board in collaboration with most of the authors of the original chapters of key relevance.The book is specifically designed to complement the UEMS breast surgery exam which is held once a year. In addition there are two feeder courses for the exam, the EBSQ exam Preparatory Course by the Division of Breast Surgery and the Advanced Course on Breast Cancer by the ESSO, each of which run yearly. There are several other postgraduate courses that could support by the book. The book is also of interest to candidates sitting the FRCS exam with a special interest in breast surgery. The last Chapter describes the format of the exams, the scoring system and presents examples of both, the written (MCQ) and the oral examination. The MCQ part contains a questions section with 25 MCQs, including the correct answers at the end. A Clinical Case scenario is also presented with indicative questions similar to those discussed during the oral exam and a list of Academic papers included for discussion in recent oral exams, along with indicative questions is also included.Table of ContentsForeword by the UEMS: Vassilios Papalois: President.- Foreword by C Markopoulos, President of Division of Breast Surgery.- Foreword by ESSO: Tibor Kovacs, President.- Foreword by EUSOMA: Isobel Rubio, President.- Section 1. LW and CM to lead.- Anatomy and physiology of the breast and axilla..- Epidemiology of breast cancer and risk factors.- The genetic basis of breast cancer, risk assessment and management.- Breast screening in normal and high risk populations.- Breast pathology (including multifocal, multicentric, biological subtypes, gene arrays, margins).- Breast imaging.- Diagnosis and staging of breast cancer.- DCIS.- Section 2. Surgery to the breast and axilla. IR and LW to lead.- Mastectomy (including SSM, NSM).- Breast conservation.- Axillary surgery and management, including SLNB, ANC, tSLNB, axillary RT, Z11, adverse effects such as lymphoedema..- Surgery for stage 3, stage 4 and locally recurrent disease (including surgical principles after NACT).- Section 3. Oncoplastic and reconstructive surgery. LW and TK.- Therapeutic mammoplasty: oncology, techniques, outcomes..- Breast reconstruction (immediate and delayed, immediate delayed, techniques, oncology, RT impacts, implants, flaps etc).- Lipomodelling.- Breast implants (to include types, practical aspects of use, adverse events including BIALCL, leakage, capsule formation etc.- Section 4. Adjuvant and neoadjuvant therapies. LW and CM.- Endocrine therapy.- Chemotherapy.- Biological therapy.- Bisphosphonates.- Radiotherapy (IMRT, CT, Protons, IORT, brachytherapy).- Section 5. Management of metastatic breast cancer, LW and CM.- Systemic therapy.- Surgery for metastatic disease (oligometastatic, primary cancer, bone metastases).- Radiotherapy for metastatic disease: bone, soft tissue, brain (SABR, gamma knife).- Section 6. Breast cancer in special groups, LW and CM.- Elderly.- Young patients, including fertility preservation, BRCA carriers.- Pregnancy.- Male BC.- Occult primary.- Section 7. The academic viva. CM .- Statistics for clinical trials.- How to critique a paper.- Key trials.

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book SynopsisThis comprehensive, illustrated guide presents representative general surgery, including gastrointestinal tract, hepatobiliary and inguinal hernia. Surgery is generally based on the microanatomy; however, in practice surgery involves more dynamic and floating anatomy. In the last decade, the methods have been constantly improved, shedding new light on classical anatomical science. Laparoscopic is one such methodology. All illustrations presented in this book have been drawn by the author – a pioneering surgeon – and show real-world procedures. All the methods introduced are practical and have been refined based on the precise clinical and embryological anatomy. This unique book offers readers essential insights into efficient and high-integrity surgeries in abdominal region. As such, it is a valuable resource for all gastrointestinal surgeons.Table of Contents1. Anatomy of the Stomach: Theoretical.- 2. Anatomy of the Stomach: Simplified.- 3. Distal Gastrectomy.- 4. Total Gastrectomy.- 5. Esophagectomy.- 6. Right Hemicolectomy.- 7. Anatomy of the Rectum.- 8. Appendectomy.- 9. Sigmoidectomy.- 10. Low Anterior Resection of the Rectum.- 11. Abdominoperineal Resection of the Rectum.- 12. Operation for Rectal Prolapse (Altemeier's Operation).- 13. Hemorrhoidectomy.- 14. Right Hepatectomy.- 15. Lateral Segmentectomy of the Liver.- 16. Laparoscopic Cholecystectomy.- 17. Open Cholecystectomy.- 18. Pancreatoduodenectomy.- 19. Anatomy of the Inguinal Canal.- 20. Repair of Inguinal Hernia.

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Book SynopsisThis highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.Table of Contents1 History, Advancements, and Future Strategies 2 Molecular basis of BRCA1 and BRCA2 - Homologous recombination deficiency and tissue-specific carcinogenesis 3 Genetic Testing 4 Variants of uncertain significances in hereditary breast and ovarian cancer 5 Genetic counseling in Hereditary Breast and Ovarian Cancer 6 Hereditary Breast Cancer 7 Hereditary Ovarian Cancer 8 Risk-Based Breast Cancer Screening 9 Chemoprevention for Breast Cancer 10 Chemoprevention for Ovarian Cancer 11 Risk-Reducing Mastectomy (RRM) 12 Risk-reducing salpingo-oophorectomy (RRSO) 13 Panel Testing 14 Germline Findings through Precision Oncology for Ovarian Cancer 15 Germline Findings from Genetic Testing for Breast Cancer 16 Hereditary Breast and Ovarian Cancer (HBOC) Database 17 Ethical Issues: Overview in Genomic analysis and Clinical Context 18 PARP Inhibitors-Mechanism of action 19 PARPi - Efficacy in Hereditary Breast Cancer 20 Efficacy of Poly ADP-Ribose Polymerase Inhibitors for Hereditary Ovarian Cancer

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