Congenital diseases and disorders Books

Book SynopsisThe indispensable guide to all aspects of clinical care, the Oxford Handbook of Endocrinology and Diabetes has been fully updated for its fourth edition, providing comprehensive coverage of both disciplines in a practical and concise format. Featuring new chapters on transition in endocrinology and diabetes, practical nursing considerations, and the genetics of endocrinology, and expanded sections on inherited endocrine syndromes and MEN, it retains the clear organisation and layout for ease of reference as the previous edition over a broader range of topics. Combining authority, relevance, and reliability, this title includes new therapies and guidelines alongside ''clinical pearl'' and ''tricky situation'' boxes to aide readers in rare or complicated situations. This is the must-have guide for all trainees and specialist nurses in endocrinology and diabetes.Trade ReviewI highly recommend this book, which is useful for subspecialty trainees to reference in day-to-day practice when they have certain clinical questions. Not only does the book do a great job of concisely organizing the extensive information related to endocrinologic disorders, but it also provides additional reading articles and guidelines for readers looking to comprehend and navigate the field of endocrinology. * Keunyoung Kim, MD(Rush University Medical Center), Doody's Listings *Overall, this is an excellent, high quality and considering it is a handbook, it is quite in depth and would appeal to a wide number of healthcare professionals. * Dr Harry Brown, Glycosmedia *This book is a useful reference text for diabetes and endocrinology that can be used in the day-to-day workplace. * BMA Medical Book Competition 2010 *This is an excellent pocket guide for endocrine disorders. This edition has been extensively updated, providing a great resource for endocrinologists and non-endocrinologists alike. * Ronald N Cohen MD, University of Chicago Medical Center, Doody's Notes *...this is an incredible resource with immense attention to detail...it is hugely valued by SpRs. The micro-details on genetics...impact of complementary medicine...specific aspects of perinatal care...reproductive etc etc...all fantastic...this book is at the highest level...no computer login required...it's cyber-attack proof, is sitting in my work bag and likely staying there... * Dr Andrew Solomon, FRCP, Consultant Physician Diabetes, Endocrinology and General (Internal) Medicine *Review from previous edition Pleasingly the coverage in both endocrinology and diabetes is pretty comprehensive and is useful to be both junior and senior hospital staff as well as GPs. Even so, despite the excellent and good depth coverage, the book remains a portable and accessible volume. I used it in primary care both as a reference source, particularly trying to sort out a patient problem and reading for interest. Its readability and ability to get straight to the point were for me the highlights...There are also topics covered that you may not expect, for example near the end there is an excellent chapter on obesity which impacts on a great deal of everyday practice, all in all this is an excellent, well priced book which can be most useful in everyday clinical practice. * Dr Harry Brown *Table of Contents1: Mark Vanderpump: Thyroid 2: Niki Karavitaki, Chris Thompson, and Iona Galloway: Pituitary 3: Jeremy Tomlinson: Adrenal 4: Waljit Dhilo, Melanie Davies, Channa Jayasena, and Leighton Seal: Reproductive endocrinology 5: Catherine Williamson and Rebecca Scott: Endocrinology in pregnancy 6: Neil Gittoes and Richard Eastell: Calcium and bone metabolism 7: Ken Ong and Emile Hendricks: Paediatric endocrinology 8: Helena Gleeson: Transition in endocrinology 9: Karin Bradley: Neuroendocrine disorders 10: Paul Newey: Inherited endocrine syndromes and MEN 11: Antonia Brooke and Andrew McGovern: Endocrinology and aging 12: Antonia Brooke, Kagabo Hirwa, Claire Higham, and Alex Lewis: Endocrinology aspects of other clinical or physiological situations 13: Marta Korbonits and Paul Newey: Genetics of endocrinology 14: Anne Marland and Mike Tadman: Practical and nursing aspects of endocrine conditions 15: Gaya Thanabalasingham, Alistair Lumb, Helen Murphy, Peter Scanlon, Jodie Buckingham, Solomon Tesfaye, Ana Pokrajac , Pratik Choudhary, Patrick Divilly, Ketan Dhatariya, Ramzi Ajjan, and Rachel Besser: Diabetes 16: Fredrik Karpe: Lipids and hyperlipidaemia 17: John Wilding: Obesity 18: Peter Trainer and Phillip Monaghan: Laboratory endocrinology

Read more less

Book SynopsisDown syndrome is a developmental disorder caused by the presence of an extra copy of chromosome 21. This extra genetic material causes changes in the production of various proteins, such as enzymes and cell adhesion molecules, which can disrupt metabolic pathways and cause defects in organ development. This title explains this genetic disease.

Read more less

Book SynopsisDrs. Bharati and Lev share the knowledge they''ve accumulated through the study of the pathology of congenital heart disease as seen in this century. Their detailed studies of over 6,300 congenitally malformed hearts give them a unique and comprehensive perspective on this topic. This monograph reports the results of their analyses and includes 2,700 excellent photographs. This book will be of significant interest to those working with or studying about congenital heart disease. This book will help clinicians and surgeons to diagnose congenital heart disease. Likewise, it offers protocol for correcting the lesions, nonsurgically and surgically. Concurrently, the text offers fertile ground for selective basic science specialities: genetics, immunology and molecular biology. Epidemiologists, statisticians and computer experts will want to review this book.Trade Review"This is a good, short compilation of data on relatively rare forms of ventricular tachycardia, that is, those found in the structurally normal heart. This book provides a ready reference on these patients as well as an extensive reference list for further review in a specific area as needed." (Cardiology News) "...an excellent book which serves as a superb summary of an exploding field of knowledge. I would highly recommend this text for cardiology house officers, general cardiologists, and internists interested in arrhythmias." (PACE)Table of ContentsAcknowledgments. Preface. Abbreviations Used in This Book.. VOLUME 1. Part I. 1. Introduction. 2. General Concepts in Pathology of Congenital Heart Disease. 3. Methods of Examination. 4. Dissection of the Heart. 5. Internal Examination. 6. Anatomy of the Normal Heart. 7. Architecture of the Ventricular Myocardium. 8. Embryology of the Heart. 9. Terminology and Classification.. Part II. 10. Tetralogy of Fallot. 11. Double Outlet Right Ventricle: General Concepts and Subaortic Ventricular Septal Defect. 12. Double Outlet Right Ventricle with Doubly Committed and Noncommitted Type of Ventricular Septal Defect. 13. Double Outlet Right Ventricle: Complicated Types. 14. Double Outlet Right Ventricle with Subpulmonic Ventricle Septal Defect: Taussig-Bing Right Ventricular Type and Mild Overriding of the Pulmonary Trunk. 15. Taussig-Bing Group of Hearts: Taussig-Bing Intermediate and Left Ventricular Types. 16. A Concept of Transposition: Complete Transposition with Normal Architecture Without Ventricular Septal Defect. 17. Complete Transposition with Normal Architecture with Ventricular Septal Defect. 18. Complete Transposition with Pulmonary Stenosis. 19. Complete Transposition with Common Ventricle. 20. Complete Transposition with Tricuspid Stenosis. 21. Complete Transposition with Tricuspid Atresia. 22. Complete Transposition with Mitral Atresia or Marked Mitral Stenosis. 23. Complete Transposition with Common Atrioventricular Orifice. 24. Unusual Complete Transposition Complexes: Double Outlet Left Ventricle. 25. Truncus Arteriosus Communis. 26. Pulmonary Atresia with Ventricle Septal Defect: Pseudotruncus. 27. Tricuspid Atresia: Tricuspid Atresia Without Transposition. 28. Tricuspid Stenosis Complexes: Tricuspid Stenosis with Pulmonary Atresia. 29. Unusual Tricuspid Stenosis Without Transposition - With Normal or Increased Pulmonary Flow: Tricuspid Stenosis Without Transposition. 30. Atrial Septal Defect, Secundum. 31. Atrial Septal Defect, Primum. 32. Atrial Septal Defect, Proximal Septal: Sinus Venosus Type. 33. Atrial Septal Defect, Coronary Sinus Type. 34. Atrial Septal Defect, Combined Secundum and Primum, or Common Atrium. 35. Ventricular Septal Defect. 36. Common Atrioventricular Orifice: Complete Type. 37. Common Atrioventricular Orifice: Intermediate Type. 38. Total Anomalous Pulmonary Venous Drainage. 39. Partial Anomalous Pulmonary Venous Drainage. 40. Patent Ductus Arteriosus. 41. Aorticopulmonary Septal Defect. 42. Atrial Septal Defect and Ventricular Septal Defect. 43. Atrial Septal Defect and Patent Ductus Arteriosus. 44. Atrial Septal Defect, Ventricular Septal Defect, and Patent Ductus Arteriosus. 45. Ventricular Septal Defect and Patent Ductus Arteriosus. 46. Hypoplasia of the Aortic Tract Complex. 47. Coarctation of the Aorta: Fetal Coarctation. 48. Transitional Coarctation of the Aorta. 49. Paraductal (Juxtaductal or Adult) Coarctation of the Aorta. 50. Isolated or Pure Pulmonary Stenosis (Normal Aortic Root). VOLUME 2. 51. Ventricular Septal Defect with Pulmonary Stenosis. 52. Aortic Stenosis. 53. Idiopathic Hypertrophy with Fibroelastosis. 54. Origin of One or Both Coronary Arteries from the Pulmonary Arterial Tree. 55. Ebstein's Anomaly. 56. Vascular Rings. 57. Abnormal Position of the Heart or its Component Chambers: Mixed Levocardia. 58. Positional Variations of the Heart and Their Significance. 59. Dextroposition. 60. Dextracardia. 61. Isolated Levocardia. 62. Mesocardia. 63. Single Ventricle with Small Outlet Chamber. 64. Straddling and Displaced Atrioventricular Orifices and Valves (Tricuspid and Mitral). 65. Relationship of Single Ventricle and Small Outlet Chamber to Straddling and Displaced Tricuspid Orifice and Valve. 66. The Concept of Single Ventricle Complex as Distinct from that of Tricuspid Atresia Complex. 67. Inverted Transposition with Left Atrioventricular Valve Atresia: Mixed Levocardia with Ventricular Inversion and Inverted Transposition with Left Atrioventricular Valve Atresia. 68. Glycogen Storage Disease. 69. Gargoylism. 70. Connective Tissue Dyscrasia: Marfan's Syndrome. 71. Congenital Polyvalvular Disease. 72. Congenital Mitral Stenosis. 73. Congenital Mitral Insufficiency. 74. Mitral Atresia with Ventricular Septal Defect Complex. 75. Aortic Atresia with Ventricular Septal Defect. 76. Pulmonary Atresia with Tricuspid Insufficiency. 77. Aortic Stenosis and Mitral Stenosis Complex. 78. Cor Triatriatum Sinistrum (Double Left Atrium). 79. Aneurysm or Ruptured Aneurysm of the Aortic Sinus of Valsalva (or Fistula). 80. Aneurysm of the Coronary Artery with Fistulous Communication with Cardiac Chambers. 81. Abnormal Course or Narrowing of the Pulmonary Trunk and its Branches. 82. Origin of a Right Pulmonary Artery from the Ascending Aorta (Hemitruncus). 83. Abnormal Blood Supply to a Lung from the Thoracic or Abdominal Aorta. 84. Double Heart. 85. Primary Pulmonary Hypertension. 86. Premature Closure or Narrowing of the Foramen Ovale. 87. Absence of Transverse Arch (Interrupted Aortic Arch) with Ventricular Septal Defect. 88. Stenosis or Atresia of the Pulmonary Veins. 89. Other Complexes. 90. Incidental Anomalies. 91. Undiagnosed Hearts. 92. Postoperative Congenital Hearts. 93. Conduction System Problems (Including Sudden Death, Uhl's, Floppy Mitral Valve, Coronary Artery Anomalies, and Atypical Hypertrophic Cardiomyopathy). 94. Congenital Cardiac Malformations Related to Cocaine and/or Other Drug Addiction in the Mother; Normal or Aquired Heart Diseases. 95. Hearts not Examined or Animal. 96. Congenital Hearts Seen According to Complex. 98. The Future. 99. References. Index to Volumes 1 and 2.

Read more less

Book SynopsisNeurology trainees will learn of presentations and diagnostic features from a wide range of neurological disorders including infective, inflammatory, neoplastic and functional neurology. Patient perspectives offer the personal impact of the specific neurological condition to further understanding of the different disorders and enhance patient care.Table of ContentsSection I. Visual Disturbance; 1. Weight loss effects on vision and limbs; 2. Adult-onset visual loss; 3. A bee of a syndrome; 4. Multiple problems; 5. Chasing periorbital nerves; 6. High pressure; 7. Test characteristic limitations; 8. Temporary visual failure; 9. Chasing the clot; Section II. Headache and Pain: 10. Losing volume; 11. Where is the pus?; 12. Recurrent acute headaches; 13. A 'never' recurring event; 14. Headache and fever; 15. Brain infection; 16. Headache and droopy eye; 17. Facial somatic mosaicism; 18. An alarm clock headache; Section III. Weakness: 19. Bleeding brain; 20. A battery issue; 21. Symptoms took years to develop; 22. High-frequency improvement; 23. Singling out dermatomes; 24. Asthmatic neurology; 25. Neurological consequences of infection; 26. When speech and swallow fail; 27. Recurrent weakness; 28. Increasing golfing handicap; Section IV. Behavioural and Language Changes: 29. Emotional consequences; 30. Covalent cascade; 31. Progressive silence; 32. Personality change; 33. Evolving and changing neurology; Section V. Confusion: 34. Clouding of consciousness in hospital; 35. Leaky effects of rising pressure; 36. Smoking encephalopathy; 37. Losing running memories; Section VI. Movement Disturbances: 38. Involuntary arm movement; 39. Salt control; 40. A young man with more than dizziness; 41. Late Familial Falling; 42. Non-familial falling; 43. Shaking leg; 44. A viral opportunity; 45. More searching for causes of progressive unsteadiness; Section VII. Acute Onset of Neurological Symptoms: 46, A neurological miscarriage; 47. Am I repeating myself?; 48. A raspberry causing trouble; 49. Different spells; 50. Following the eyes; 51. Fuming loss of consciousness; 52. From skin to brain; 53. Self-tolerance failure; 54. Not a minor problem; 55. Seized; Index.

Read more less

Book SynopsisTest your knowledge or prepare for Boards with this collection of unusual and challenging patient studies focused on detecting valvular, congenital or vascular disease. Contains over 90 case histories with self-test questions designed to test the reader's knowledge and reinforce clinical best practices Focuses on diseases of valvular, vascular or congenital origin, and on comparatively rare disorders/diseases, rather than coronary artery disease, to help readers improve their skills at interpreting and making decisions based on physical examination and basic, non-invasive imaging modalities Each case is paired with original materials - e.g. x-rays, echocardiograms, lab reports, charts so readers can work through their diagnosis using the same information as the physician who treated the patient originally An ideal companion for those approaching board review or recertification or who want to improve skills in physical diagnosis of cardiTrade Review“This book will challenge the problem-solver, improve the reader's knowledge of cardiology, and help prepare the trainee for the cardiology board examination. Its specific strong points include an attractive cover, paper of high-grade stock, excellent colored illustrations, well-constructed diagrams and tables, an assortment of worthwhile images, and a wealth of detailed and practical information on a wide variety of valvular, congenital, and rare forms of cardiovascular disease. Especially useful are the discussion, key points, and references that conclude most of the patient studies.” (Texas Heart Institute Journal, 1 August 2015) Table of ContentsAbout the Author vii Preface ix Acknowledgments xi Abbreviations xiii Worked Example xv Companion Website xix Patient Study 1 46-year-old chronic alcoholic man with heart failure and sudden death (1968) 1 Patient Study 2 24-year-old man with dyspnea, edema, and a heart murmur (1973) 7 Patient Study 3 27-year-old man with hemoptysis and dyspnea (1973) 19 Patient Study 4 22-year-old female with exertional chest pain and palpitations (1974) 23 Patient Study 5 40-year-old man and the perils of walking in the street (1997) 30 Patient Study 6 54-year-old man with dyspnea and a lifelong murmur (1974) 37 Patient Study 7 26-year-old man with an asymptomatic heart murmur (1979) 44 Patient Study 8 20-year-old man with chest pain and a life-long heart murmur (1979) 50 Patient Study 9 23-year-old female with heart failure and a heart murmur (1975) 59 Patient Study 10 17-year-old man with fever, myalgias, and a heart murmur (1977) 71 Patient Study 11 24-year-old man with left leg pain (1977) 80 Patient Study 12 48-year-old female with dyspnea (1976) 87 Patient Study 13 19-year-old man with easy fatiguability, cyanosis, and clubbing (1977) 93 Patient Study 14 29-year-old man with an asymptomatic murmur and an abnormal chest X ray (1977) 100 Patient Study 15 32-year-old man with a history of dyspnea and syncope over last 38 years (1967) 107 Patient Study 16 55-year-old female with chest pain and hematemesis (1993) 120 Patient Study 17 27-year-old man with decreased exercise tolerance and a heart murmur (1982) 126 Patient Study 18 29-year-old man with pleuritic chest pain, dyspnea, and cardiomegaly (1985) 135 Patient Study 19 25-year-old man with new onset of hemoptysis (1986) 142 Patient Study 20 80-year-old man with hemoptysis and dyspnea (1998) 149 Patient Study 21 21-year-old man with hemoptysis, cyanosis, and a heart murmur (1989) 157 Patient Study 22 23-year-old female with chest pain and visual symptoms (1992) 167 Patient Study 23 Approximately 40-year-old man with new onset of a murmur and heart failure (1975) 173 Patient Study 24 54-year-old female with altered mental status (1993) 182 Patient Study 25 74-year-old female admitted with abdominal pain followed by shock (1994) 187 Patient Study 26 Approximately 82-year-old female admitted with recurrent lower GI bleeding and a known abdominal aortic aneurysm (2001) 191 Patient Study 27 41-year-old female with chest pain and a heart murmur (1994) 197 Patient Study 28 48-year-old man with leg numbness and weakness (1994) 201 Patient Study 29 67-year-old female with chest pain and a new heart murmur (1995) 208 Patient Study 30 62-year-old man with chest pain and hypertension (1996) 214 Patient Study 31 17-year-old female with fatigue and a heart murmur (1997) 219 Patient Study 32 31-year-old female with fatigue and syncope (1997) 224 Patient Study 33 33-year-old female with dyspnea, edema, and a murmur (1995) 231 Patient Study 34 21-year-old man with dyspnea and chest pain (1995) 238 Patient Study 35 54-year-old man with chest pain, hypertension, and abdominal pain (2005) 245 Patient Study 36 19-year-old female with aching legs on exertion (1995) 249 Patient Study 37 58-year-old man with dyspnea, chest pain, and Sjorgen’s syndrome (1996) 256 Patient Study 38 37-year-old ex cocaine user with dyspnea and a heart murmur (1998) 261 Patient Study 39 24-year-old female with a heart murmur (1997) 266 Patient Study 40 34-year-old Asian female with heart failure(2001) 272 Patient Study 41 73-year-old man with chest pain and hypertension (2000) 278 Patient Study 42 42-year-old female with dyspnea and a heart murmur (2001) 283 Patient Study 43 37-year-old female with dyspnea and cyanosis (1999) 289 Patient Study 44 27-year-old female with dyspnea, a murmur, and kyphoscoliosis (1996) 296 Patient Study 45 41-year-old man with presumed cardiomyopathy (2002) 302 Patient Study 46 78-year-old female with chest pain and a heart murmur (2002) 310 Patient Study 47 31-year-old man with long-standing clubbing (1997) 317 Patient Study 48 79-year-old man with dyspnea and edema 3 years after an operation (1995) 328 Patient Study 49 37-year-old female with recurrent syncope and heart failure (1984) 336 Patient Study 50 33-year-old man with new onset of hemiplegia (1985) 342 Patient Study 51 44-year-old female with chest pain and dyspnea (2008) 345 Patient Study 52 80-year-old diabetic female with an abnormal echocardiogram and no CVS symptoms (2008) 352 Patient Study 53 42-year-old female with palpitations and an abnormal echocardiogram (2006) 355 Patient Study 54 53-year-old alcoholic man and the perils of winter (2009) 360 Patient Studies 55–56 90-year-old female with dyspnea and hemoptysis (2000) 366 Patient Study 57 1-month-old Infant with unsuspected cardiac pathology on echocardiography (2002) 372 Patient Study 58 69-year-old man with lower extremity pain (2008) 374 Patient Study 59 71-year-old man with dizziness and weakness (2010) 379 Patient Study 60 20-year-old man with pleuritis and fever (1995) 383 Patient Study 61 20-year-old man with swollen face and chest pain (2008) 389 Patient Study 62 17-year-old female with an acute myocardial infarction (2013) 395 Patient Study 63 66-year-old diabetic female with ICD dysfunction (2008) 401 Patient Study 64 39-year-old man with chest pain and syncope (2011) 406 Patient Study 65 58-year-old female with dyspnea, hypertension, and hematuria (2008) 413 Crossword Puzzle Pediatric cardiology and general medical crossword puzzle 419 Subject Index 421 Patient Studies Index 423 Disease Classification Index 425 Answers to Crossword Puzzle 427

Read more less

Book SynopsisThis volume commences with a survey of the history of VCFS and provides an exhaustive description of the 190 phenotypes associated with the syndrome, including speech and language, hearing, cognition, and many other critically affected areas. The genetics of VCFS are extensively covered.

Read more less

Book SynopsisThis book on Hirschsprung''s disease (HD) contains a complete update on the various aspects of this disease. It is the collaboration of an international group of paediatric surgeons well-known in their fields who are experts in this pathology and of other prestigious professionals -- neurobiologists, physiologists, geneticists, paediatricians, and histopathologists. Over the course of 28 chapters, these authors describe the latest advances in the diagnosis and treatment of this pathology. The first part is an update of the anorectal physiology, pathophysiology, genetics, and histopathology. The second part deals with the clinical manifestations and diagnosis in the new-born, with especial reference to manometric diagnosis during the neonatal period and to the morphological and radiological study. Other important chapters are devoted to differential diagnosis, preoperative care, indications for ostomy, and preparing the child for the pull-through. The third part describes the various classical surgical options (Swenson, Duhamel, Soave, Rehbein), and the new methods using laparoscopy and transanal pull-through, which have been the major breakthrough in the treatment of this condition. Total colonic aganglionosis and the critical review of the different surgical techniques occupy two magisterial chapters. The fourth part comprises an extensive exposition of enterocolitis in HD, the long-term results following surgery, other variants of HD, and two novel chapters in treatises on this disease (intestinal transplants and nutrition). In the Annex, parents of children with this disease describe their experience. The book ends with a final chapter devoted to informed consent. This book will be an invaluable reference for paediatric surgeons and paediatricians and gastroenterologists, and has a special interest for parents of children with Hirschsprung''s disease.

Read more less

Book SynopsisIt has been almost 150 years since Dr Langdon Down first brought to our attention people with Down syndrome. Life expectancy, level of intellectual functioning, physical health, psychological health, social functioning, and integration into society are all issues that have markedly changed since 1866. The matter of ageing in people with Down syndrome has consistently remained an area of intense interest. This book documents the most important published literature on the issue of dementia and Down syndrome published since Dr Langdon Down''s momentous paper. Further, a number of publications from the general population which have had significant impact in the field of dementia and Down syndrome, and a number of papers in young adults and children with Down syndrome that have important implications for the ageing population have been included.

Read more less

Book SynopsisPrader-Willi syndrome (PWS) is a rare, genetic, multisystemic disorder, characterised by short stature, muscular hypotonia, intellectual disability, behavioural and psychological problems and frequently hypogonadism and impaired growth hormone secretion. PWS arises due to loss of function of paternally-expressed, imprinted genes from chromosome region 15q11-q13. In new-borns and infants, the syndrome presents symptoms of muscular hypotonia and nutritional difficulties, which from the age of approximately two years is replaced by hyperphagia often leading to severe obesity. With increasing age the behavioural and psychological problems increase while the muscular hypotonia improves. During the last decades the knowledge of different aspects of PWS has increased and accordingly the treatment possibilities. However, no specific treatment exists and thus problems continue lifelong. Taking care of PWS patients is therefore a demanding task and necessitates a solid knowledge and understanding of the disorder as well as a multidisciplinary approach. This book will provide professionals taking care of patients with PWS with updated and comprehensive information and advise. The content is built up logically and it will be easy to navigate between the chapters, which cover all clinically relevant issues, genetics, signs and symptoms in children and adults, treatment, words from patients and parents, supporting organisations, and from a parent to a PWS patient.

Read more less

Book SynopsisArteriovenous malformations (AVM) represent some of the most complex and challenging pathologies for the modern physician to properly diagnose and manage. In this comprehensive guide, we detail the natural history, diagnosis and management of AVMs. The first eight chapters are dedicated to brain AVMs. Chapter 1 describes the natural history of brain AVMs, the understanding of which is crucial to deciphering the relative risks and benefits of AVM treatment. Chapter 2 focuses on the surgical treatment of brain AVMs. Chapters 3 and 4 delineate the role of endovascular embolization in the management of brain AVMs. Chapter 5 analyzes the outcomes of stereotactic radiosurgery for Spetzler-Martin grade III AVMs, which are the most heterogeneous subgroup of AVMs. Chapter 6 describes the role of stereotactic radiosurgery for large brain AVMs, which are notoriously difficult to safely and effectively treat by any means. Chapter 7 focuses on heavily charged particle beam radiosurgery for brain AVMs. Chapter 8 puts it all together by analyzing the relationships and interactions among the different treatment modalities for brain AVMs; when utilized synergistically, the morbidity of each therapy is minimized while its maximum benefit is extracted. The last two chapters are dedicated to Osler-Weber-Rendu syndrome, also known as hereditary hemorrhagic telangiectasia (HHT). Chapter 9 describes the genetics, pathogenesis, and management of HHT, with a focus on the diagnosis of pulmonary AVMs. Chapter 10 evaluates the role of endovascular intervention in the treatment of pulmonary AVMs.

Read more less

Book SynopsisIt is the year 2019, and fear looms in on the world. A deadly virus, one with the ability and venom to wipe away half of the world's 7.8 billion people, or even extinct humanity forever, has emerged. And now, mankind must summon all the strength, knowledge, experiences, science, technology, resilience, courage, and everything else that they have at their disposal, to combat this dark, mysterious, dangerous disease and all its entities. World War III could just end up being between man and the Coronavirus Disease.Table of Contents1. Introduction viii 2. Chapter 1 - Brief history of pandemics and how they changed the world? 1 3. Chapter 2 - Life before COVID-19 7 4. Chapter 3 - Living in fear 13 5. Chapter 4 - How COVID-19 attacks the body? 24 6. Chapter 5 - Living with Anosmia and Parosmia 33 7. Chapter 6 - UK government's unprecedented stimulus package response 37 8. Chapter 7 - COVID-19 and the rest of the world 43 9. Chapter 8 - The second wave 56 10. Chapter 9 - The vaccines and their problems 63 11. Chapter 10 - The out of control second wave and the new variants 73 12. Chapter 11 - A third deadly wave 85 13. Chapter 12 - Track and trace and privacy concerns 90 14. Chapter 13 - A new global financial crisis 94 15. Chapter 14 - When pandemics collide. COVID-19 and Obesity 103 16. Chapter 15 - COVID-19 and mental health 108 17. Chapter 16 - New Coronavirus UK government's acts 117 18. Chapter 17 - How COVID-19 changed the world? 124 19. Chapter 18 - Learning from the mistakes. WHO and UK government's errors 131 20. Chapter 19 - Is it fair? 139 21. Chapter 20 - COVID-19 conspiracies 145 22. Epilogue - Will COVID-19 ever be eradicated? 152 23. Confirmed cases and death tolls country by country table data 156 24. Country by country vaccine data 172 25. Bibliography 174

Read more less

Book SynopsisIrritable Bowel Syndrome, commonly known as IBS, causes misery to millions. After the common cold, it is the most frequent reason for visiting a GP. Fortunately, much can be done to control and even overcome the worst symptoms through diet and exercise. The First Year: Irritable Bowel Syndrome is an informative patient-expert's guide to managing this condition. Heather Van Vorous, herself an IBS sufferer for over two decades, helps the reader understand how the digestive system works and why things go wrong. She then details the range of treatment options and vital lifestyle changes necessary for improvement, explaining:· Five key strategies to control symptoms· Ten commandments of eating for IBS· How exercise can help· How stress affects IBS and how to manage it· Effective complementary therapies· How to eat safely at restaurants, with friends and when travelling

Read more less

Book SynopsisFragile X syndrome is one of the main causes of child developmental delay and autism spectrum disorders. A premutated form of the same gene is also the basis for neurological disabilities in adults. This book breaks down the complex science of this genetic disorder and provides the facts and advice that every bewildered parent or professional needs to support individuals with Fragile X syndrome.This is a straightforward introduction that clearly explains the condition on both a scientific and practical level. With sections on diagnosis, symptoms and treatment, as well as discussions of various emotional and behavioural considerations, this guide covers all aspects of Fragile X syndrome, its implications, and the possibilities open to families affected by it. It demonstrates how, with the right therapies, progress can be made and emphasises how music can be used effectively to promote communication, interaction, fine motor skills and responsiveness in children with the condition.This is an essential reference tool for families of individuals with Fragile X syndrome, as well as therapists and healthcare professionals who are unfamiliar with the condition and are looking to find out more.Trade ReviewFernandez, a scientific advisor in the Spanish Fragile X Federation, and Aldridge, co director of the Nordoff-Robbins Zentrum, Witten, Germany, walk readers through the heredity aspects of Fragile X, its symptoms, diagnosing the syndrome, and appropriate interventions...Professionals may find more support here than parents, yet the lack of popular material on Fragile X means this is an important contribution. -- Library JournalTable of Contents1. What is Fragile X Syndrome? 2. Understanding Heredity: Genetic Factors and Inheritance. 3. The Common Symptoms of Fragile X Syndrome. 4. Associated Fragile X Syndromes: Primary Ovarian Insufficiency and Fragile X Tremor/Ataxia Syndrome. 5. Diagnosing Fragile X Syndrome and Its Implications. 6. Interventions for Fragile X Syndrome. 7. Talking with the Family. Glossary. Further Reading. Fragile X Weblinks.

Read more less

Book SynopsisA number of books have been written relating to congenital heart disease, but generally, they reflect individualised medical management of local practice and philosophies. Although this book assumes a prior working knowledge of congenital heart disease, it aims to provide the reader with a reference guide to be utilised at the bedside.The main aspiration of this book is to provide a comprehensive, affordable guide for paediatric, neonatal and adult nurses of young people with congenital heart disease, in this highly challenging speciality. This book is primarily written for nursing staff focusing on a multidisciplinary team approach to managing children. It is also a valuable tool for community staff, dieticians, doctors, neonatal staff, perfusionists, pharmacists, physiological measurment technicians, physiotherapists, psychologists, social workers, theatre staff, and other personnel who come into contact with this group of children.Table of ContentsThe Normal Heart. Cardiac Assessment and Investigations. Acyanotic defects, Obstructive Defects. Cyanotic Defects. Cyanotic and Acyanotic Defects. Acquired Heart Disease. Ardiopulmonary Bypass. Elective Admission for Cardiac surgery. Respiratory Management. Cardiovascular Management. Haematological and neurological Management. Renal, Fluid and Electrolyte Management and gastrointestinal. Management. The Dying Child. Drug Management.

Read more less

Book SynopsisDesigned as reference material to increase knowledge of the human body. Beautiful full-colour illustrations help enhance understanding of the body or illness. Suitable for healthcare professions, patients, students, educators and parents.

Read more less

Book SynopsisDesigned as reference material to increase knowledge of the human body. Beautiful full-colour illustrations help enhance understanding of the body or illness. Suitable for healthcare professions, patients, students, educators and parents.

Read more less

Book Synopsis

Read more less

Book Synopsis

Read more less