Immunology Books

Book SynopsisTrade Review"The Autoimmune Solution is a medical breakthrough. Dr. Myers' protocol is a proven way to heal and reverse any illness on the autoimmune spectrum. This book revolutionizes the way we understand and treat autoimmunity and I am thrilled to be able to recommend it to my patients." -- Mark Hyman, M.D., author of The Blood Sugar Solution 10- Day Detox Diet "Dr. Amy Myers is an inspiring, pioneering voice in the prevention and treatment of autoimmune conditions. This guide presents her straightforward, action-oriented plan for healing your gut and detoxifying your surroundings. The Autoimmune Solution has the power to change the lives of millions." -- Robb Wolf, author of The Paleo Solution "Dr. Amy Myers begins by writing that modern medicine failed her when her immune system failed. I believe this was a blessing in disguise. Dr. Myers has made this her life's work and her book The Autoimmune Solution is a gift to humanity." -- Alejandro Junger, M.D. author of Clean "The Autoimmune Solution is a long awaited and scientifically validated approach to autoimmune conditions that relegates the standard approach of simply managing symptoms to being a relic of the past. Dr. Myers' plan will fundamentally change the trajectory of your health for the better." -- David Perlmutter, M.D., author of Grain Brain "At long last, a solution to autoimmune disorders! With her proven, easy-to-follow health protocol, Dr. Amy Myers turns conventional medicine on its head and, in the process, offers hope, answers, and security to the millions of people coping with a full spectrum of inflammatory illness and autoimmune diseases." -- Frank Lipman, M.D., author, educator, and founder of the Eleven Eleven Wellness Center in New York City "Dr. Amy Myers lives and breathes advocacy. She supports the unfolding of you most easeful, fulfilled self and helps to uncover and clear what's in the way with gentle (but firm) support, humor and comprehensive tools. I so appreciate her passion for learning and health and trust her completely." -- Kathlyn Hendricks, Ph.D., BC-DMT, Co-Author of Conscious Loving and The Conscious Heart "Those with autoimmune issues should welcome this helpful and hopeful resource from a physician who walks her talk." -- Publishers Weekly "Americans who suffer from psoriasis, type 1 diabetes, and other autoimmune diseases will find many alternative ideas in this guide...her recipes for dishes like a salmon avocado bowl seem healthy and tasty, and her bibliography is thorough." -- Booklist "The Autoimmune Solution busts many of the conventional wisdom myths surrounding autoimmune disease, explaining where conventional medicine goes wrong and empowering patients to be proactive...The best part of all of this is that Amy's language is very approachable and down-to-Earth." -- The Paleo Mom

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Book SynopsisFully updated to include the latest guidelines for treatment, new diseases and therapies, and filled with cross-references for a comprehensive overview of the field, the Oxford Handbook of Clinical Immunology and Allergy 4th edition is the invaluable guide for all clinicians and laboratory staff interested in immunology.Trade ReviewThis is a good pocket reference for trainees (medical students, residents, and fellows) undergoing training/rotation in clinical immunology and allergy. It presents the main relevant information in bulleted lists under each diagnosis commonly encountered in the clinical setting. * Patty Chi, Doodys book reviews *Review from previous edition This is an excellent pocket reference for clinical immunology and allergy. The sections are arranged to allow for quick retrieval of key facts. It is small and convenient to carry...[it] will be particularly helpful to students or physicians who want a quick, convenient resource to retrieve key facts in a broad range of topics related to this field. * Doody's Notes *Table of Contents1: Primary immunodeficiency 2: Secondary immunodeficiency and other host-defence syndromes 3: Allergic disease 4: Autoimmunity and the endocrine system 5: Autoimmunity affecting the nervous system 6: Autoimmunity associated with cardiac, respiratory, and renal disease 7: Autoimmunity in gastrointestinal disease 8: Autoimmunity in liver disease 9: Autoimmune haematological disorders 10: Autoimmune skin disorders 11: Autoimmune eye disease 12: Connective tissue disease 13: Vasculitis 14: Miscellaneous conditions, including autoinflammatory syndromes 15: Transplantation 16: Immunotherapy 17: Immunochemistry 18: Autoantibodies 19: Allergy tests 20: Cellular investigations 21: Tissue typing 22: Quality and managerial issues

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Book SynopsisCelebrated science writer Carl Zimmer’s classic book, updated in a new edition, is an eye-opening look at Covid-19 and the many other viruses that shape our planet and ourselves.Trade Review"A smart, beautiful, and somewhat demented picture book that's likely to give you a case of the willies. In the best way possible."-- "Boing Boing, on the first edition" "Absolutely top-drawer popular science writing. . . . Zimmer's information-packed, superbly readable look at virological knowledge awakens readers to the fact that not only are viruses everywhere but we couldn't live without them."-- "Booklist, starred review, on the first edition" "As with any great journey, this virtual tour opens your eyes and expands your horizons. . . . Reading Zimmer's work is like hanging out with the smartest, most interesting guy you have ever met as he regales you with tales of his travels and fascinating finds along the way."-- "Science News, on the first edition" "Just about everything you've always wanted to know--and a lot you'll probably wish you didn't know--about the viruses that have caused humanity so much grief throughout history."-- "Forbes, on the first edition" "Succinct yet elegantly written. . . . A fascinating and enlightening introduction."-- "Guardian, on the first edition" "Zimmer reshapes our understanding of the hidden realities at the core of everyday existence. . . . Concise and illuminating."-- "Washington Post, on the first edition" "Zimmer is one of the best science writers we have today. A Planet of Viruses is an important primer on the viruses living within and around all of us--sometimes funny, other times shocking, and always accessible. Whether discussing the common cold and flu, little-known viruses that attack bacteria or protect oceans, or the world's viral future as seen through our encounters with HIV or SARS, Zimmer's writing is lively, knowledgeable, and graced with poetic touches."--Rebecca Skloot, author of The Immortal Life of Henrietta Lacks "on the first edition"

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Book SynopsisA Waterstones science book of the yearA book of the year for The Times and Sunday TimesNew York Times editor''s choice Winner of the Giles St Aubyn Award for Non-Fiction''The book that might change the world ... This is luxury-class science writing'' TELEGRAPH''One of the best books of any genre that I''ve read in 2023, this superbly-written book ... will fascinate absolutely everyone'' FORBES''A delight. To learn more about phages is to discover fascinating details about a hidden world'' NATURE''Outstanding'' CLIVE MYRIEThe viruses that do us harm are vastly outnumbered by viruses that can actually save lives. These good viruses are called ''phages'', and they are the most abundant life form on Earth.The Good Virus reveals how these weird and wonderful microbes shape our health, support our ecosys

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Book SynopsisThe Inflammation Spectrum, Dr Will Cole's follow up to Ketotarian, teaches us how inflammation is often the catalyst for most common health woes.Arriving at a time where issues of inflammation and gut health are becoming increasingly prominent within mainstream discourses, Dr Will Cole offers us a solution to this growing issue. The Inflammation Spectrum teaches us that ultimately how we feel is symbiotically linked to what we consume; indeed, food, in Cole's words, 'constantly and dynamically influences' our health. Subsequently he teaches readers how to do nutrition the right way, providing us with a personal guide which seeks to aid readers to find out which foods their bodies love, hate and need to feel great!Cole's book informs us to think twice before consuming pharmaceutical drugs to "fix" issues of inflammation and instead proposes that readers reassess their eating habits, using 'food as thy medicine'. This book, Dr Mark Hyman suggests, is for 'anyone who is fed up with fad diets' as Cole uses his years of experience in functional-medicine to teach us how to love our bodies enough to nourish it with delicious, healing foods. From personal quizzes to scientific breakdowns The Inflammation Spectrum offers empowering advice and puts readers on the path to achieving food freedom and optimal health.

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Book SynopsisDonald Thomas provides information for women who wish to become pregnant and advises readers about working with a disability, complementary and alternative medicine, infections, cancer, and a host of other topics.Trade ReviewA wealth of detail on the many ways lupus affects the human body, the various related treatment options, a range of patient resources for support, and more... a caring, comprehensive guide to understanding and coping with lupus. Library Journal The Lupus Encyclopedia is [a] carefully-researched, easily-understood and comprehensive book. It is, as it claims, an ENCYCLOPEDIA... If you [could have] only one book in your library about lupus, The Lupus Encyclopedia might well be it. The Lupus Guru There is great depth and much to learn from reading and referring to this important book... This book should stand the test of time as one of the great books about this complex auto-immune disease. Lupus, the Adventure Between the Lines I highly recommend The Lupus Encyclopedia. It's an amazing source of information, and I feel empowered by the fact that I have a reliable resource to turn to whenever I need it. No matter what your symptoms are or the level of severity, you owe it to yourself to get this book. Lupine Life The Lupus Encyclopedia is a book that that every lupus patient should have in their home library. It's the most comprehensive lupus book out there, and is a valuable resource for anyone searching for a detailed and in-depth explanation of this complicated and mysterious disease. -- Sara Gorman Despite Lupus This is a highly readable medical text... This encyclopedia would be useful for public libraries, medical libraries, or academic libraries. -- Amy B. Parsons American Reference Books Annual ... packed with facts, advice and encouragement... The Nursing Times This title strikes a pitch perfect balance: on one side, there is information of value to those suffering from or caring for the condition, on the other, data suitable for clinicians seeking a better general understanding of the condition. This volume represents outstanding value for money and would be a useful addition to medical, healthcare and personal bookshelves. Reference Reviews We can't imagine a more thorough, readable guide to lupus than this. Pain-Free LivingTable of ContentsList of IllustrationsList of TablesForeword, by George C. Tsokos, MDPrefaceAcknowledgmentsPart I: Definitions, Causes, and Diagnosis of Autoimmune Disease1. What Is Lupus and How Is It Diagnosed?2. The Other Systemic Autoimmune Diseases3. What Causes Lupus?4. The Meaning of All Those Test ResultsPart II: How Lupus Affects the Body5. How SLE Directly Affects the Body6. Constitutional Symptoms7. The Musculoskeletal System8. Skin and Mucous Membranes9. Blood and Lymph Systems10. The Respiratory System11. The Heart and Blood Vessels12. The Urinary System13. The Nervous System14. The Exocrine Gland System15. The Digestive System16. Eyes17. The Endocrine System18. The Reproductive System and Pregnancy19. Special Populations and Surgery20. PrognosisPart III: Other Complications of Lupus and Their Treatments21. Heart Attacks and Strokes22. Infections23. Cancer and SLE24. Osteoporosis25. Avascular Necrosis of Bone26. Adrenal Insufficiency27. Fibromyalgia28. Gastroesophageal Reflux and Stomach UlcersPart IV: Treatment of Lupus29. General Treatment of Lupus30. Anti-Malarials31. Steroids32. Immunosuppressants33. Biologic Agents34. Benlysta: The First FDA-Approved Drug for Lupus in More Than Fifty Years35. Other Therapies for SLE36. Prescription Pain Medicines37. Future Treatments for SLE38. Nonmedical Therapies for Lupus39. Complementary and Alternative MedicinePart V: Practical Matters40. Talking to Your Doctor and Deciphering Symptoms41. Becoming Pregnant, Breast-Feeding, and Using Contraception42. Health Insurance and Affording Healthcare43. Working and Dealing with Disability44. The Lupus Secrets ChecklistPatient ResourcesBibliographyIndex

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Book SynopsisSelected as a Doody's Core Title for 2022 and 2023! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. Reflects the latest advances in the field, including current insights on immune system function, both basic and translational. Contains 50 chapters written by leaders in all subfields of immunology. Provides extensive coverage of the molecular biology that explains the dynamics underlying immune disorders and their treatment. Includes 10 entirely new chapters covering invertebrate and plant immunity, eosinophils, innate lymphoid cells, gamma/delta T cells, NKT and MAIT cells, immunometabolism, maternal-fetal immunology and more. Contains abundant full-color illustrations and tables that provide essential information at a glance. Features annual updates from the authors to the VST version, keeping you current with changes in this dynamic field from the experts. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. Table of ContentsContents Contributors viiForeword xiiiPreface xvii Section I. Introduction to Immunology1 Overview of the Immune System — 1Martin F. Flajnik, Steven M. Holland, Nevil J. Singh2 History of Immunology — 29Edward J. Moticka Section II. Evolution of the Immune System3 The Insect Immune System — 52Sara Cherry, Nicolas Buchon4 Evolution of the Vertebrate and Lower Deuterostome Immune System — 79Martin F. Flajnik5 The Plant Immune System — 134Roger W. Innes Section III. Cellular Pathways and Processes in Immunity6 Immunometabolism — 161Jonathan D. Powell, Chirag H. Patel, Im- Hong Sun7 Regulated Cell Death in the Immune System — 204Douglas R. Green, Sebastian Ruehl8 Lymphoid Tissues and Organs — 228Martin F. Flajnik, Nancy H. Ruddle9 Type I Cytokines, Interferons, and Their Receptors — 258Achsah D. Keegan, Warren J. Leonard10 Tumor Necrosis Factor Superfamily of Cytokines and Receptors — 308Carl F. Ware, Nancy H. Ruddle11 Chemokines and Chemokine Receptors — 344Philip M. Murphy Section IV. Innate Immunity12 Pattern Recognition Receptors and the IL- 1 Family — 386Rajendra Karki, Thirumala- Devi Kanneganti13 The Complement System — 416Erin E. West, Claudia Kemper14 Neutrophils — 455Andres Hidalgo, Mariana J. Kaplan15 Macrophages — 469Gwendalyn J. Randolph16 Mast Cells and Basophils — 487Mindy Tsai, Stephen J. Galli17 Eosinophils — 519Elizabeth A. Jacobsen, Hirohito Kita18 The Biology of Natural Killer Cells and Innate Lymphoid Cells — 537Vincent Peng, Marco Colonna Section V. Adaptive Immunity19 The Major Histocompatibility Complex — 573David H. Margulies, Kannan Natarajan, Jamie Rossjohn, James McCluskey20 Classical Antigen Processing and Presentation — 622Jonathan W. Yewdell, Paul Roche, Laurence C. Eisenlohr21 Immunoglobulins: Structure and Function — 644Mohamed Khass, David Wald, Neil S. Greenspan, Harry W. Schroeder, Jr22 Immunoglobulins: Molecular Genetics — 671Sebastian D. Fugmann23 T Cell Antigen Receptors and Antigen Recognition — 702Mark M. Davis, Yueh- Hsiu Chien24 Antigen Receptor Signaling — 734Nevil J. Singh, Gideon Wolf 25 B Cell Development in Mice — 774Nicole Baumgarth26 B Cell Responses — 798Claude- Agnès Reynaud, Jean- Claude Weill27 T Cell Development in the Thymus — 823Avinash Bhandoola, Remy Bosselut, Yousuke Takahama28 CD4+ Helper T Cells: Differentiation, Flexibility, and Heterogeneity — 856John J. O’Shea, Marion Pepper, Marc K. Jenkins, Danielle A. Chisolm29 Regulatory T Cells — 874Ethan M. Shevach30 CD8+ T Cell Memory — 924Francis R. Carbone, Thomas Gebhardt31 Cytotoxic Effector Functions — 944Morgan Huse Section VI. Integrative Immunology32 Immunologic Tolerance — 971Colin C. Anderson, Troy A. Baldwin, Peter A. Bretscher33 Fc Receptors and Their Role in Immune Regulation and Inflammation — 1008Jeffrey V. Ravetch, Aaron Gupta, Falk Nimmerjahn34 Dendritic cells — 1034Roxane Tussiwand, Pierre Guermonprez, Simon Yona35 Gamma Delta T Cells — 1054Adrian C. Hayday36 CD1- Restricted T Cells — 1102Pankaj Sharma, Florian Winau37 Mucosal- Associated Invariant T Cells and Other MR1- Reactive T Cells — 1137Sidonia B. G. Eckle, Wael Awad, Jamie Rossjohn, James McCluskey, Alexandra J. Corbett38 The Mucosal Immune System — 1178Yasmine Belkaid, Brian L. Kelsall, Warren Strober39 Introduction to Neuroimmunology — 1212Andrea Francesca Salvador, Jonathan Kipnis40 Vaccines — 1231Bali Pulendran41 Maternal- Fetal Immunology — 1283Gabrielle Rizzuto, Adrian Erlebacher Section VII. Immune Responses to Pathogens42 Response to Parasites — 1325David Sacks, Marion Pepper, Mary F. Fontana, P’ng Loke43 Immune Responses to Bacteria — 1355S. Celeste Morley, Moon H. Nahm44 Response to Viruses — 1399Hildegund C. J. Ertl45 Immunology of HIV Infection — 1445Gaurav D. Gaiha, Douglas S. Kwon Section VIII. Immunological Disease States and Immunodeficiency46 Autoimmunity and Autoimmune Diseases — 1465Gustaf Christoffersson, Ken T. Coppieters, Matthias von Herrath, Dirk Homann47 Immunologic Mechanisms of Allergic Disorders — 1515Stéphanie Lejeune, Kari C. Nadeau, David W. Scott, Joshua D. Milner48 Transplantation Immunology — 1549Megan Sykes, Anita S. Chong, Markus Y. Mapara49 Cancer Immunology and Immunotherapy — 1589Thomas F. Gajewski, Justin Kline50 Inborn Errors of Immunity — 1619Isabelle Meyts, Jean- Laurent Casanova, Luigi D. Notarangelo Index 1649

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Book SynopsisUnderstand how our immune system fights disease and enables the body to heal itself.'Thrilling... Reads like the best kind of adventure story' STEPHEN FRY'Excellent' TIM SPECTOR, Sunday Times bestselling author of Spoon-Fed Here, Professor Daniel Davis charts the groundbreaking scientific quest to understand how it fights disease and enables the body to heal itself. He explains how it is affected by stress, sleep, age and our state of mind, and reveals how all of this knowledge is now unlocking a revolutionary approach to medicine and well-being. The Beautiful Cure tells a dramatic story of detective work and discovery, of puzzles solved and of the mysteries that remain, and of lives sacrificed and saved. SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE 'Wonderful... recounts in exceptionally clear and sympathetic prose how research into the immune system has resulted in a health revolution' HENRY MARSH 'Thoroughly absorbing... Davis is a wonderful storyteller' BILL BRYSONTrade ReviewThrilling ... An eye-opening tour de force of scientific writing that reads like the best kind of adventure story -- Stephen FryOne of the best accounts I have yet come across of the nature of biological science … Daniel Davis’s wonderful book recounts in exceptionally clear and sympathetic prose how research into the immune system has resulted in a health revolution -- Henry Marsh * New Statesman *Thoroughly absorbing ... Davis is a wonderful storyteller -- Bill BrysonTerrific ... Davis relates the extraordinary modern developments in supercharging the body’s own immune system to fight disease, and one day maybe even eliminate cancer -- Steven Poole * *****Telegraph *Thrilling … Do not underestimate the importance of immunology. This field relates to you personally -- Adam Rutherford * Guardian *An inspirational book that not only reveals the secret joys of scientific discovery but is jam-packed full of revelations for non-scientists * Mail on Sunday *Forget AI, robotics, the internet of things. This is where the future feels strange and exciting: in the 'inner universe' of our immune system, and in the radically new therapies that are using it to conquer disease * Sunday Times *Highly readable, beautifully researched, backed up with notes, references and interviews by Davis himself, whose status as an immunology professor confers added credibility. He believes that we now know enough about the major components and interactions of the immune system to begin manipulating them to cure diseases such as cancer. We stand, he predicts, on the threshold of a medical revolution * New Scientist *A sweeping tour d’horizon … lucid and entertaining … Much as Siddhartha Mukherjee did in his book The Gene, Davis expertly weaves together human stories and scientific endeavour * The Times *New ways to treat cancer, diabetes, arthritis and other age-related diseases … Davis is a sure and engaging guide to these developments * Observer *

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Book SynopsisLippincott® Illustrated Reviews: Immunology, 3rd Edition, offers an engaging, vividly illustrated presentation and all of the popular learning features of the Lippincott® Illustrated Review series to reinforce essential immunology concepts and connect basic science to real-life clinical situations. Like other titles in this series, this dynamic resource follows an intuitive outline organization and boasts a wealth of vibrant illustrations and study aids that clarify complex information and ensure retention. Whether used as a review text for a short immunology course or paired with Lippincott® Illustrated Reviews: Microbiology for a combined microbiology/immunology course, this revised and updated edition familiarizes readers with the latest practices in immunology and emphasizes clinical application to deliver unparalleled preparation for exams and clinical practice. Revised and expanded content equips you with the most current perspectives and practices in clinical immunology. More than 300 full-color, annotated illustrations clarify complex immunology concepts in vivid detail. Clinical Application boxes demonstrate the practical application of immunology concepts in clinical scenarios. Chapter Study Questions and Answers test your retention and comprehension. NEW! Cross-references to other Lippincott® Illustrated Reviews titles help you grasp how immunological concepts relate to other basic sciences. Chapter summaries and chapter overviews highlight the most important concepts and takeaways in each chapter. Updated end-of-text review questions boost your test-taking confidence.

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Book SynopsisIn this revelatory memoir, doctor Cynthia Li shares the truth about her struggle with a disabling autoimmune illness, the limitations of Western medicine, and what sufferers need to know to truly begin healing-mind, body, and spirit.Cynthia Li had it all: a successful career in medicine, a loving marriage, children on the horizon. But it all came crashing down when, within months of having her first child, she developed mysterious symptoms that baffled her doctors. After two years of "normal" test results with no relief from Western medicine, Li was no longer well enough to practice. Her quest for health became a solo odyssey-she had to find a way to heal herself.Brave New Medicine details the disabling autoimmune crisis that forced Li to question her own medical training and embrace the integrative principles of functional medicine to unlock her body's innate healing capacity . With the insight of an MD who was able to dissect and heal the root causes of her own autoimmune illness-one that conventional medicine said was incurable and irreversible-Li relates her story, including the emotional and spiritual shifts that occurred while investigating her true self, beyond illness and the conditions of the body.Millions of people are affected by chronic health conditions in the United States. But while issues such as chronic fatigue syndrome (CFS/ME) and fibromyalgia are receiving more and more attention, patients struggling with these mysterious autoimmune conditions are still dismissed by doctors and scientists in the established medical community. This is the harsh reality that doctor-turned- "difficult patient" Li faced firsthand when she developed autoimmune thyroiditis and chronic hypothyroidism (or Hashimoto's).Drawing on ancient healing arts, cutting-edge science, evolutionary biology, and the power of laughter and pleasure, this memoir offers support, validation, and a new perspective for anyone dealing with chronic illness or another health crisis. By sharing her own autoimmunity struggle, Li reveals the insider knowledge you need to start your own healing journey.

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Book SynopsisSystemic sclerosis or scleroderma is an autoimmune disease characterised by widespread microangiopathy, immune system alterations and fibrosis of the skin and internal organs. This book presents current research in the study of the symptoms, diagnosis and treatment of scleroderma. Topics discussed include the identification and treatment of the pulmonary manifestations of systemic sclerosis; interstitial lung disease in systemic sclerosis; nailfold capillaroscopy and early diagnosis of systemic sclerosis; localised scleroderma; evaluation of a new CENPB epitope array for systemic sclerosis-associated centromere autoantibodies; and iloprost in the treatment of Raynaud phenomenon secondary to scleroderma.

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Book SynopsisThe human body is a marvel - but what happens when it comes under attack? A fascinating guide to why we get sick and how we get better.The human body is a marvel - but what happens when it comes under attack? A fascinating guide to why we get sick and how we get better. ‘Lovely, warm, erudite and, above all, chatty.’ Chris van Tulleken, author of Ultra Processed People Nature wants you dead. Not just you, but your children and everyone you have ever met and everyone they have ever met; in fact, everyone. It wants you to cough and sneeze and poop yourself into an early grave. It wants your blood vessels to burst and pustules to explode all over your body. And - until recently - it was really good at doing this… The subject of infection and how to fight it grows more urgent every day. How do pathogens cause disease? And what tools can we give our bodies to do battle? Infectious is not onlyTrade Review‘Tregoning is a gifted writer of popular science. He has a knack for explaining the intricacies of vaccines and immunity without dumbing them down, and he moves things briskly along with a barrage of often self-deprecating humor.’ * Wall Street Journal *‘This book catapults us to the frontier of the vital science of infections and immune responses. Tregoning is a perfect guide, writing with wit and intelligence about a subject that surely everyone feels the importance of now. Brilliant and right on the zeitgeist.’ -- Daniel M. Davis, author of The Beautiful Cure‘Packed with fascinating facts, intriguing anecdotes and more than a few Dad jokes, Infectious is an expertly guided, pacey tour through the world of all the stuff that’s trying to kill us and how our immune systems and human ingenuity are fighting back.’ -- Dr Kat Arney, science communicator and author of Rebel Cell‘What a book! A book for everyone, an expert, or an interested lay person, young or retired or somewhere in the middle. Informed, engaging, generous and superbly written. If you have secretly wondered about some of the information of the last year (as we all have) and want one book to explain it all with total clarity – this is the book for you. I started it and could not put it down. The best, most accessible, high-quality science book I have read this year. Utterly brilliant.’ -- Jeremy Farrar, Director of the Wellcome Trust‘To call this book timely would be yet another contender for understatement of this strange decade. As the pandemic has upended the world and ravaged the population, it’s a duty for all of us civilians to turn to experts like Dr Tregoning with due humility, and educate ourselves about what’s happening to us, how we got here, how we’ve dealt with similar events in the past, and how we might get through this. This book is thorough, engaging, entertaining and utterly vital.’ -- Frank Turner, singer-songwriter‘Lovely, warm, erudite and, above all, chatty.’ -- Chris van Tulleken‘Despite the serious subject, Tregoning (who got COVID-19) maintains a sense of humor… This is a fascinating and timely account of often unheralded scientists heroically battling bacteria and viruses.’ * Booklist *

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Book SynopsisCase Studies in Infectious Disease presents 40 case studies featuring the most important human infectious diseases worldwide. Fully revised and updated in this second edition, the book describes the natural history of infection from point of entry of the pathogen through to clinical management of the resulting disease or condition. A further 8 case studies have been provided online as supplementary material, and these can be downloaded by students. Five core sets of questions are posed in each case, with the answers covering the nature of the infectious agent, route(s) of spread and of infection, pathogenesis of disease, host response to infection, clinical manifestations, diagnosis, treatment and prevention. This standardized approach provides the reader with a logical basis for understanding these diverse and medically important organisms and diseases, fully integrating microbiology and immunology throughout.KEY FEATURES High-resolution photos accompany each case, from the causative agents of disease to the clinical manifestations of the infection. Exquisite artwork helps to illustrate important concepts throughout the book. Eight new cases added to this new edition, extending coverage of important infectious diseases of worldwide significance. A standardized set of core questions allows students to compare directly differences between microbes such as their structure, clinical manifestations, host response, pathogenesis and availability of vaccines. Questions and answers available online, test the readerâs understanding of each case study. The book provides essential case-based learning for undergraduate and graduate microbiology students, while medical students and trainee physicians will also find the up-to-date information on 48 globally important infectious diseases outlined in a clear, digestible form, invaluable during undergraduate studies and in future clinical practice. Trade Review"a handsome, excellent book on most common pathogens, with a clear orientation to immunology, physiopathology, and microbiology … It reads well and is an excellent textbook for medical students and a good source of illustrations, tables, and question ideas for teachers." Gary P. Wormser and Guillaume Béraud for Clinical Infectious Diseases."a valuable compilation of information on the most common diseases that cause illness and death worldwide. The presentation format with distinct sections makes it readable and well suited for either students just learning about the pathogens causing infectious disease or clinicians who need an update. The level of detail is well thought out and gives the reader a useful summary of each pathogen and disease state. The condensed presentations make it a good reference source for those with insufficient time to read through more detailed textbooks." Philip S. Brachman for Emerging Infectious Disease.Table of ContentsAspergillus fumigatus Borrelia burgdorferi and related species Campylobacter jejuni Candida albicansChlamydia trachomatis Clostridiodies difficile Cytomegalovirus Echinococcus spp. EnterovirusesEpstein-Barr virus Escherichia coli Giardia lamblia Helicobacter pylori Hepatitis B virus Hepatitis C virusHerpes simplex virus Histoplasma capsulatum Human immunodeficiency virus Influenza virus Leishmania spp. Leptospira spp. Listeria monocytogenes Mycobacterium leprae Mycobacterium tuberculosis Neisseria gonorrhoeae Neisseria meningitidis Norovirus Plasmodium spp. Respiratory syncytial virus Rickettsia spp. Salmonella typhi Schistosoma spp. Staphylococcus aureus Streptococcus pneumoniae Streptococcus pyogenes Toxoplasma gondii Trypanosoma spp.Trichophyton spp. and dermatophytesVaricella-zoster virus Wuchereria bancrofti Plus online cases:Bartonella bacilliformis BrucellaCoxiella burnetti Dengue virusEnterococcus faecalis and E. faeciumMycobacterium abscessusSARS-CoV-2 Streptococcus mitis

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Book SynopsisWe''re told that we need to exercise to stay healthy, but we''re not told HOW to exercise. We''re certainly not told how to exercise with an autoimmune condition. This is the definitive book you need to help you understand and support your body when exercising with an autoimmune condition.Here, Zoe tells us of her own health journey, whilst exploring the benefits of exercise for someone with an autoimmune condition and how you can get onto a plan that suits your needs. She uses case studies, experts and her own research to explore:- the benefits of exercising with a chronic condition- the barriers to exercising with a chronic condition and how to overcome them- how to keep motivation high when exhausted - which exercises you should do (complete with illustrations)- how to adapt your exercises depending on your condition- how to get into the right mindset with exerciseZoe teaches with compassion and understanding that is unique in this

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Book SynopsisTable of ContentsPART I Principles of Immune Response 1 The Human Immune Response 2 Organization of the Immune System 3 Innate Immunity 4 Antigen Receptor Genes, Gene Products, and Co-Receptors 5 The Major Histocompatibility Complex 6 Antigens and Antigen Presentation 7 B-Cell Development and Differentiation 8 Immunoglobulin Function 9 T-Cell Development 10 T-Cell Activation and Tolerance 11 Helper T-Cell Subsets and Control of the Inflammatory Response 12 Cytotoxic T Lymphocytes and Natural Killer Cells 13 Regulatory Immune Cells 14 Cytokines and Cytokine Receptors 15 Chemokines and Chemokine Receptors 16 Lymphocyte Adhesion and Trafficking 17 Death Pathways and Immunogenicity PART II Fundamentals of Host-Environmental Interactions 18 Human Genomics in Immunology 19 Regulatory RNA in Immunologic Diseases 20 Immunometabolism 21 Immune Deficiencies at the Extremes of Age 22 The Microbiota in Immunity and Inflammation PART III Host Defenses to Infectious Agents 23 Immunology of the Skin 24 Immunology of Mucosal Surfaces 25 Host Defenses to Viruses 26 Host Defenses to Intracellular Bacteria 27 Host Defenses to Extracellular Bacteria, Including Spirochetes 28 Host Defenses to Fungi 29 Host Defenses to Protozoa 30 Host Defenses to Helminth Infection 31 Emerging Pandemic Infectious Disease Threats PART IV Immune Deficiency and Immune Regulatory Disorders 32 Approach to the Evaluation of the Patient With Suspected Immunodeficiency 33 Primary Antibody Deficiencies 34 Primary T-Cell Immunodeficiencies 35 Genetic Disorders of Interferons-, Interleukin-17, Interleukin-18, and Nuclear Factor-?B-Mediated Immunity 36 Hemophagocytic Lymphohistiocytosis 37 Autoinflammatory Syndromes 38 Immune Regulatory Disorders 39 Neutrophils and Neutrophil Disorders 40 Complement and Complement Disorders 41 Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome 42 Autoantibody-Mediated Phenocopies of Primary Immunodeficiency Diseases PART V Allergic Diseases 43 Allergic Airway Diseases 44 Mast Cells and Mast Cell Disorders 45 Eosinophils and Eosinophilic Disorders 46 Urticaria, Angioedema, and Anaphylaxis 47 Allergic Reactions to Stinging and Biting Insects 48 Atopic and Contact Dermatitis 49 Food Allergy 50 Drug Hypersensitivity PART VI Systemic Immune Diseases 51 Mechanisms of Autoimmunity 52 Systemic Lupus Erythematosus 53 Rheumatoid Arthritis 54 Juvenile Idiopathic Arthritis 55 Sjögren's Syndrome 56 Scleroderma-Systemic Sclerosis 57 Inflammatory Muscle Diseases 58 Spondyloarthritis 59 Small- and Medium-Vessel Primary Vasculitis 60 Large Vessel Vasculitides 61 Antiphospholipid Syndrome PART VII Organ-Specific Inflammatory Disease 62 Immunohematologic Disorders 63 Bullous Diseases of the Skin and Mucous Membranes 64 Immunology of Psoriasis 65 Myasthenia Gravis 66 Multiple Sclerosis 67 Autoimmune Peripheral Neuropathies 68 Immunologic Renal Diseases 69 Immunologic Mechanisms of Atherosclerosis and Myocarditis 70 Autoimmune Thyroid Diseases 71 Type 1 Diabetes 72 Immunologic Lung Diseases, 919 73 Chronic Obstructive Pulmonary Disease and Emphysema 74 Immunologic Ocular Disease 75 Immunologic Diseases of the Gastrointestinal Tract 76 Inflammatory Hepatobiliary Diseases PART VIII Immunology and Immunotherapy of Neoplasia 77 Lymphoid Leukemias 78 Lymphomas 79 Monoclonal Gammopathies 80 Immune Responses to Solid Tumors and Immune Checkpoint Therapy 81 CAR T-Cell Therapy PART IX Medical Management of Immunological Diseases 82 Immunoglobulin Therapy: Replacement and Immunomodulation 83 Glucocorticoids 84 Immunomodulating Drugs 85 Protein Kinase Antagonists 86 Biologic Response Modifiers 87 Vaccines 88 Allergen Immunotherapy for Allergic Diseases PART X Transplantation 89 Solid Organ Transplantation: Rejection, Immunosuppression, and Tolerance 90 Allogeneic Transplantation for Immunodeficiency 91 Gene Therapy for Primary Immune Deficiency Diseases 92 Hematopoietic Stem Cell Transplantation for Malignant Diseases PART XI Diagnostic Immunology 93 Flow Cytometry 94 Assessment of Functional Immune Responses in Lymphocytes 95 Assessment of Neutrophil Function 96 Assessment of Human Allergic Diseases Appendix 1: Selected CD Molecules and Their Characteristics Appendix 2: Laboratory Reference Values Index

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Book SynopsisWinner, 2018 Donald W. Light Award for Applied Medical Sociology, American Sociological Association Medical Sociology SectionWinner, 2018 Distinguished Scholarship Award presented by the Pacific Sociology AssociationHonorable Mention, 2017 ESS Mirra Komarovsky Book Award presented by the Eastern Sociological SocietyOutstanding Book Award for the Section on Altruism, Morality, and Social Solidarity presented by the American Sociological AssociationA rich, multi-faceted examination into the attitudes and beliefs of parents who choose not to immunize their childrenThe measles outbreak at Disneyland in December 2014 spread to a half-dozen U.S. states and sickened 147 people. It is just one recent incident that the medical community blames on the nation's falling vaccination rates. Still, many parents continue to claim that the risks that vaccines pose to their children are far greater than their benefits. Given the research and the unanimity of opinion within the medical community, many asTrade Review"Several recent books have delved into the history and science of vaccines and immunity, and the anxieties that accompany them. Jennifer Reich … brings meticulousness and sensitivity to this emotional issue. … It is Reich’s book that may prove the most convincing to anti-vaxxers." -- New York Review of Books"Risk is one of the operative words central to sociologist Jennifer Reichs remarkably calm book on current vaccination practices in North America. Risk is what parents, paediatricians and policymakers must evaluate in their roles as caregivers, primary-care doctors and advisers The group of parents Reich interviewed over a 10-year period that has informed this book are the university-educated ubermoms who favour organic food and have a tendency to avoid gluten and dairy productsThe doctors Reich interviewed recognise that some vaccination is better than none and that being patronising, bossy or confrontational is not in the best interest of the child or the wider community. It is a stance Reich shares." * Times Higher Education *"Recent outbreaks of preventable diseases such as measles and whooping cough are focusing attention on this issue, making Reich's able contribution especially pertinent." * Kirkus Reviews *"In her engaging book,Calling the Shots: Why Parents Reject Vaccines, Jennifer Reich focuses on this last group of privileged, vocal parents, a group with the potential to disrupt the balance of infectious disease control across the country. This exceptionally timely book also confronts the challenges posed by science skepticism amid a declining sense of public obligation and the increasing dictate that health is each familys personal responsibility." * Contemporary Sociology *"Jennifer Reichs new book, Calling the Shots: Why Parents Reject Vaccines, is an essential contribution to the story of vaccines in contemporary U.S. society that should make it impossible to tell such simple stories about vaccine resisters any longer." * American Journal of Sociology *"A timely intervention into recent anti-vaccination controversies, Jennifer Reich’s Calling the Shots unpacks the logics behind vaccine refusal through interviews and ethnographic studies of parents who refuse vaccinations." -- Science, Medicine, and Anthropology"Calling the Shots is intellectually rigorous and politically engaged scholarship of the highest quality. Jennifer Reich illuminates the attitudes, beliefs, and behaviors surrounding childhood immunization, one of the most important and contested public health policy issues of our day. Debates about vaccine refusal have too often been marked by over-simplification and unfounded assumptions, and Reichs thorough, meticulous analysis provides a much-needed corrective.-James Colgrove,author of State of Immunity: The Politics of Vaccination in Twentieth" * Century America *"Calling the Shots treads confidently into the explosive terrain of vaccine refusal. In this must-read exploration of the burdens of modern mothering, Reich takes seriously the desires of mothers to make their own decisions to protect their children from risks. But she also shows how anti-vaccine stances by the privileged few may undermine the social compact and threaten the public good. This is a well-written, important, and very timely book." -- Steven Epstein,author of Inclusion: The Politics of Difference in Medical Research"In this gripping book, Reich illumines the processes through which (mostly affluent) parents reject vaccines. The book impressively situates these anti-vaccine parents in a broader context. Reich carefully documents how a range of organizations including medical offices, drug companies, and child protective servicesare all players in this social drama. Reichs concept of & individualistic parenting is valuable. Since parents decisions can have dire consequences for other children, the book is not only interesting, but it is of enormous social significance.Highly recommended!" -- Annette Lareau,author of Unequal Childhoods: Class, Race, and Family Life

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Book SynopsisTrade Review“Dr. Mayer will not only open your eyes to the critical importance of the variety of microbes that inhabit our gut, but also to the broader picture of how food choices that support biodiversity can save lives, shield us from novel infections, and protect the planet. It is fascinating how choices to improve our personal health are connected to the preservation and creation of fertile soils, clean waterways and ultimately our mothership, Earth and our progeny." — Joel Fuhrman, M.D., seven-time New York Times bestselling author “In Medicine, the ‘Holy Trinity’ means something different: the brain, the gut, and the immune system. Each contributes to health through its effects on the others. We’re lucky, because Emeran Mayer is an expert in each. And he knows the only way to fix all three at once is to fix the food.” — Robert Lustig, MD., author of Fat Chance and The Hacking of the American Mind “Our entire world – the soil, the plants, even us humans – are bound together by networks of invisible microbes. In The Gut-Immune Connection, Dr. Emeran Mayer is a microbiome magician pulling back the veil on our interconnected world and then showing us how to harness nature’s healing energy. This is a life changing book by one of the great scientists of our generation. “ — Will Bulsiewicz, New York Times bestselling author of Fiber Fueled “We live in an environment dominated by ultra-processed, fast food, which is fueling disease and hurting the planet. In The Gut-Immune Connection, Dr. Emeran Mayer, draws important connections between the gut microbiome and our immune system, describing how individuals can take action to harness this powerful force to promote well-being. It is a must read for those searching for a path to better human and planetary health.” — Erica Sonnenburg, PhD, co-author of The Good Gut "Now more than ever we need to understand the critical connection between what we put in our body, and our resistance to disease. Focusing on the three foundational pillars of the gut endocrine system, immune system, and nervous system, Dr. Mayer breaks down the science and lays out a clear and attainable path to reclaim immunity, vitality, and health." — Robynne Chutkan, MD, FASG, author of Gutbliss, The Microbiome Solution & The Bloat Cure “In his new book, Dr. Mayer beautifully points out the close interconnectedness between our own health, and the health of the soil and the environment, and the crucial role that the trillions of microbes play in this planetary network. The book is both a unique collection of information, as well as an urgent call to action for everybody concerned about the deteriorating state of our universal health. “ — Yvon Chouinard, founder and owner of Patagonia, Inc. “Finally, a book that treats gut health, human health, and ecological health as one subject. A revelatory read from a doctor, writer and thinker we all need to hear from, now more than ever.” — Dan Barber, NYT Bestselling author of The Third Plate and chef of the 2 Michelin star restaurant Blue Hill and Blue Hill at Stone Barns “Dr. Mayer takes a fascinating deep dive into the microbial world that links the health of our bodies with the health of our environment, revealing the deep interconnections between the planet’s life support systems and our own.” — Liz Carlisle, PhD., author of Lentil Underground

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Book Synopsis**THE SUNDAY TIMES BESTSELLER**'Brilliant! It's hard to change your life - but this book gives you all the reasons it's possible. From the first page to the last, one revelation after another.'JEREMY VINE'Brilliant . . . especially required reading in these COVID-19 days'LIZ EARLE'Metabolism, inflammation, and immunity are three sides of the same coin. Fix one and you fix them all. Dr Aseem Malhotra offers you a way to fix all three at once, and the solution is as easy as your fork.' PROFESSOR ROBERT LUSTIG, bestselling author of Fat Chance'This remarkable book will change your life. Beautifully written, it compiles in one place the health messages we all know make sense. PROFESSOR KAROL SIKORA, leading cancer specialist and Founding Dean, University of Buckingham Medical School'Read this book and follow the plan, it may save your life.' GURINDER CHADHA, OBE, director of Bend It Like Beckham'A crystal-clear roadmap to reverse the roots causes of our poor metabolic and immune health. It is the handbook of health for our time.' MARK HYMAN, New York Times bestselling author of Food Fix*******The simple, evidence-based diet plan to rapidly improve your metabolic health, help with normal immune function and likely reduce the risk of severe effects from Covid-19.Dr Aseem Malhotra is a leading NHS-trained cardiologist and a pioneer of lifestyle medicine. He has been at the forefront of citing the health conditions which make us vulnerable to the worst effects of Covid-19. Obesity, Type 2 diabetes and heart disease are high among them - and all indicators of poor metabolic health. The good news is that in just 21 days we can prevent, improve and even potentially reverse many of the underlying risk factors that exacerbate how infections, including Covid-19, affect us and improve our ability to recover from them. Giving us the evidence-based science behind the plan, Dr Malhotra shares how simple changes to our diet as well as daily exercise and stress relief can have remarkable results in improving our markers for metabolic health, even helping to put Type 2 diabetes into remission, reduce risk factors for heart disease, decrease weight and enhance vitality.Arguing for the huge benefits to global health of these highly effective lifestyle changes, he shows how just 21 days can help us to start the journey to lead a healthier and longer life.Trade Review'This valuable and timely book is a must read.' -- KIM PEARSON, Harley Street nutritionist * London Evening Standard *'You have to get immediately The 21 Day immunity plan and take action now.' * European Scientist *'Dr Aseem Malhotra is a quite remarkable man . . . his timely, evidence-based and brilliant new 21-day immunity plan is a perfect way to take the first step to transforming your life. I wish you well on your journey to better health.' -- From the Foreword by TOM WATSON'I've been unfortunate enough to have had #COVID19. I feel had I not focused on regaining my metabolic health and sending my type 2 diabetes into remission things could have been much worse. This amazing Doctor puts his head above the parapet. I have great respect for Dr Aseem Malhotra and owe my regained metabolic health to him.' -- DEBRA SCOTT, retired civil servant'Feel good today and increase your chance of living a longer and healthier life. In this well researched book Dr Malhotra provides the science and the steps for this double win.' -- DR CAMPBELL MURDOCH, Clinical Adviser, Royal College of GPs'This game-changing book is a must-read for anyone wishing to understand the link between metabolic health and immunity.' -- DR RAVI KUMAR KAMEPALLI, Board-Certified in Infectious Diseases, Wound Care and Obesity Medicine, Augusta, USA'Dr Aseem Malhotra spells it all out right here in front of you, with a perfect combination of smart, simple strategies for prevention or management of lifestyle conditions and keeping the immune system in best shape.' -- DR CARYN ZINN, Senior Lecturer, Dietitian, AUT University, Head of Research – School of Support and Recreation, Auckland, New Zealand'This groundbreaking book empowers the reader with knowledge of the practical steps we can all take to improve our health status and protect ourselves against diseases of all kinds.' -- KIM PEARSON, Harley Street nutritionist'Brilliant . . . especially required reading in these COVID-19 days' -- Liz Earle

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Book SynopsisPublisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Maximum Retention in Minimal Time! This high-yield, rapid-fire Q&A book simulates flashcards in a book to help you review microbiology and immunology for your course exams as well as prepare for the USMLE Step 1. The convenient two-column âœflashcardâ Q&A format reinforces familiar material, while accelerating mastery of commonly tested topics. Youâll efficiently absorb a large amount of pertinent information and streamline study time by focusing only on the correct answers. Ideal for studying when time is limited, Deja Review: Microbiology and Immunology lets you review in a way that helps you cover a lot of questions in a short period of time. Featuresâ Ideal, two-column flashcard-like format helps you revi

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Book SynopsisEvery year in September the spectre of cold and flu season arrives. It has become a fact of life. We might as well allot for our sick days knowing that we will be hit at least once, if not two to three times before Spring's arrival. This title explains why some of us get sick more regularly than others and offer a proven program to stay healthy.Trade Review"This book proves that eating high nutrient dense foods is the best path to building a super immune system, leading to a healthy long life with a "sound mind" and the recipes are superb." -- Dr. Rudy Kachmann, Neurosurgeon, Kachmann Mind Body Institute "Super Immunity should be the book everyone is talking about. I encourage you to buy it, read it, and apply it so you can join the conversation on true health." -- Wayne S. Dysinger, MD, MPH, Chair, Department of Preventive Medicine, Loma Linda UniversityPresident, American College of Lifestyle Medicine "Super Immunity is a much needed book that contains the key to ending the cycle of sickness that plagues many of our lives. This is enlightened medicine, at last!" -- Dr. Alejandro Junger, New York Times bestselling author of CLEAN "Super Immunity"is a fantastic read that scientifically explains the origins of Western disease and lays out viable solutions to our unhealthy lifestyles. I will definitely be recommending this book to my patients!" -- Garth Davis MD Star of TLC's "Big Medicine", Medical Director of Bariatric Surgery at Memorial City Hospital, Houston, Texas "When it comes to diet and health, the scientific evidence shows that one size really fits all. Super Immunity offers everybody the most sensible, most effective dietary approach to become and stay truly healthy." -- James Craner, MD, MPH, FACOEM, FACP Occupational & Environmental Medicine, Reno, NV Assistant Clinical Professor, University of California San Francisco School of Medicine "Super Immunity expertly yet succinctly combines the latest nutrition and scientific research, plus a handful of anecdotes from Fuhrman's patients, into 170 pages of air-tight, irrefutable advice on how to get and stay healthy, even in an increasingly toxic and processed world." -- VegNews Magazine

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Book SynopsisTrade Review“Vividly told. ... Explicates for the lay reader the intricate biology of our immune system. ... Richtel succeeds in this formidable task.” — JEROME GROOPMAN, New York Review of Books “Deeply affecting. … A compelling modern history of—as well as an elegant defense for—the preeminent science of our time.” — Los Angeles Review of Books “Richtel brilliantly blurs the lines between biology primer, medical historical text and the traditional first-person patient story. ... Richtel harnesses his reporter’s eye for the human condition.” — Washington Post “In this thorough investigation, Richtel details the explosion of knowledge over the past 70 years. ... He weaves into his narrative four case studies [that] add a moving personal dimension.” — BBC, “10 Books to Read This Month” “One of those rare nonfiction books that transcends the genre. ... A fascinating and engrossing account of the latest, and quite astonishing, discoveries involving the human immune system. ... An inspiring and wonderful read. ... I highly recommend this extraordinary book.” — Douglas Preston, #1 bestselling author of The Lost City of the Monkey God “A thorough, richly entertaining and just-wonky-enough beginner’s class in immunology through the case studies of four patients.” — Wall Street Journal “Remarkable. … Richtel is a gifted storyteller. … A story about cutting-edge science, humanely told.” — Matt McCarthy, USA Today “Matt Richtel’s An Elegant Defense is a comprehensive and engaging primer on the body’s ‘ever-vigilant, omnipresent peacekeeping force.’ The immune system plays an essential role in fighting infections and cancer and in regulating our normal health. Read this superb book to better understand one of the enduring mysteries of human biology.” — SANDEEP JAUHAR, New York Times bestselling author of Heart: A History “An expert examination of the immune system. … Richtel illuminates a complex subject so well that even physicians will learn.” — Kirkus, STARRED review “Richtel approaches this essential subject with awe, his writing meticulous and empathic.” — Booklist, STARRED Review “Award-winning reporter Matt Richtel examines the scientific and human realities of immune anomaly through four case studies. … Through these harrowing accounts, Richtel interweaves the research history.” — Nature, “Best Science Picks” “A deeply reported and entertainingly written exploration of the human immune system and how it works.” — USA Today (”5 Books Not to Miss”) “Plumbs the enormous impact of the human immune system. … Despite the topic’s staggering complexity… the heart and craft of a fine storyteller emerges most memorably.” — Mercury News “A remarkable journey of exploration inside the human body. … Richly informative and engaging. … Eminently readable and with so many important takeaways, An Elegant Defense is well worth one’s investment of time.” — Shelf Awareness “An engaging deep dive into our immune system.” — Men’s Health “Richtel’s new book is so useful. ... Give[s] lay readers a means of understanding what’s known so far about the intricate biology of our immune systems.” — The Week, “Book of the Week” “Compelling. … Richtel enthusiastically and compassionately demystifies the science and the story of one of the most intricate and misunderstood landscapes of human biology. … A celebration of life and the journey we all share.” — Washington Independent Review of Books “Enlightening. … Readers who suffer from challenged immune systems will welcome validation for the physical and emotional trials they endure, gain deeper understanding of their ailments, and find hope for the future. Readers who are interested in the human body’s capacity to both harm or heal itself will be fascinated.” — New York Journal of Books “A deeply reported account of how the immune system works. … Richtel weaves dense, complex research into suspense and human drama; his book reads, at times, like a harrowing mystery novel.” — Spirituality and Health magazine “A hard-to-put-down account of the body’s first line of defense.” — Publishers Weekly “A sweeping overview of immunology’s history. ... The prose in An Elegant Defense is vibrant, conversational, direct and often funny. … The content is captivating and useful.” — Science News “[An] entertaining and a worthwhile read.” — The Missourian “Fascinating. ... Rooted in evidence-based research. ... Compelling.” — AudioFile "Books like An Elegant Defense give mainstream readers insights into that process, insights that run deeper than those a textbook might provide. When we understand how science really works, perhaps we will be a bit less susceptible to anti-scientific seductions. Richtel’s elegant analogies and compelling human stories will help us remember the basic concepts of modern immunology long after the jargon and acronyms have been forgotten." — Commentary “A mind-blowing page-turner with moving yet playful human dramas.” — MindBodyGreen "Fascinating read, especially in the context of a pandemic. Through four personal stories, you discover the captivating complexity of our immune system, written in such a way that it’s an easy read for the layman." — Bloomberg News, A Best Book of 2020 “A valuable read that will help you understand what it takes to stop COVID-19. … A super interesting look at the science of immunity.” — Bill Gates

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Book SynopsisTrade Review“Dr. Mayer will not only open your eyes to the critical importance of the variety of microbes that inhabit our gut, but also to the broader picture of how food choices that support biodiversity can save lives, shield us from novel infections, and protect the planet. It is fascinating how choices to improve our personal health are connected to the preservation and creation of fertile soils, clean waterways and ultimately our mothership, Earth and our progeny." — Joel Fuhrman, M.D., seven-time New York Times bestselling author “In Medicine, the ‘Holy Trinity’ means something different: the brain, the gut, and the immune system. Each contributes to health through its effects on the others. We’re lucky, because Emeran Mayer is an expert in each. And he knows the only way to fix all three at once is to fix the food.” — Robert Lustig, MD., author of Fat Chance and The Hacking of the American Mind “Our entire world – the soil, the plants, even us humans – are bound together by networks of invisible microbes. In The Gut-Immune Connection, Dr. Emeran Mayer is a microbiome magician pulling back the veil on our interconnected world and then showing us how to harness nature’s healing energy. This is a life changing book by one of the great scientists of our generation. “ — Will Bulsiewicz, New York Times bestselling author of Fiber Fueled “We live in an environment dominated by ultra-processed, fast food, which is fueling disease and hurting the planet. In The Gut-Immune Connection, Dr. Emeran Mayer, draws important connections between the gut microbiome and our immune system, describing how individuals can take action to harness this powerful force to promote well-being. It is a must read for those searching for a path to better human and planetary health.” — Erica Sonnenburg, PhD, co-author of The Good Gut "Now more than ever we need to understand the critical connection between what we put in our body, and our resistance to disease. Focusing on the three foundational pillars of the gut endocrine system, immune system, and nervous system, Dr. Mayer breaks down the science and lays out a clear and attainable path to reclaim immunity, vitality, and health." — Robynne Chutkan, MD, FASG, author of Gutbliss, The Microbiome Solution & The Bloat Cure “In his new book, Dr. Mayer beautifully points out the close interconnectedness between our own health, and the health of the soil and the environment, and the crucial role that the trillions of microbes play in this planetary network. The book is both a unique collection of information, as well as an urgent call to action for everybody concerned about the deteriorating state of our universal health. “ — Yvon Chouinard, founder and owner of Patagonia, Inc. “Finally, a book that treats gut health, human health, and ecological health as one subject. A revelatory read from a doctor, writer and thinker we all need to hear from, now more than ever.” — Dan Barber, NYT Bestselling author of The Third Plate and chef of the 2 Michelin star restaurant Blue Hill and Blue Hill at Stone Barns “Dr. Mayer takes a fascinating deep dive into the microbial world that links the health of our bodies with the health of our environment, revealing the deep interconnections between the planet’s life support systems and our own.” — Liz Carlisle, PhD., author of Lentil Underground

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Book SynopsisFrom Dr. Peter H. R. Green, internationally renowned expert on celiac disease and director of the Celiac Disease Center at Columbia University, and medical author Rory Jones, an updated fourth edition of the definitive book on celiac disease, one of the most underdiagnosed autoimmune diseases in the U.S.  Celiac Disease: A Hidden Epidemic is an indispensable guidebook for anyone with celiac disease as well as for those with gluten intolerance or food sensitivities on a gluten-free diet. Since the last edition in 2016, scientific advances have changed what we know about the disease, how it is diagnosed and treated, and the long-term effect of a gluten-free diet on the brain and body.Celiac disease is a hereditary autoimmune condition that damages the lining of the small intestine so that it cannot properly absorb food. Without essential nutrients, the entire body begins to suffer. The disease is triggered by gluten,

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Book SynopsisThe full inside story of the high-stakes, global race for the lifesaving vaccine to end the pandemic Heroic science. Chaotic politics. Billionaire entrepreneurs. Award-winning journalist Brendan Borrell brings the defining story of our times alive through compulsively readable, first-time reporting on the players leading the fight against a vicious virus. The First Shots, soon to be the subject of an HBO limited series with superstar director and producer Adam McKay (Succession, Vice, The Big Short), draws on exclusive, high-level access to weave together the intense vaccine-race conflicts among hard-driving, heroic scientists and the epic rivalries among Washington power players that shaped 18 months of fear, resolve, and triumph. From infectious disease expert Michael Callahan, an American doctor secretly on the ground in Wuhan in January 2020 to gauge the terrifying ravages of Disease X; to Robert (Dr. Bob

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Book SynopsisTable of ContentsSection 1: Immunologic Basis of Autoimmunity 1. Prelude: Historical introduction to autoimmunity and autoimmune disease 2. Structural and Functional Aspects of the Innate and Adaptive Systems of Immunity 3. General Features of Autoimmune Diseases 4. Antigen Presentation, Dendritic Cells, and Autoimmunity 5. T cells and their subsets 6. Role of Th1 Th2 Th17 Cells in Autoimmunity 7. Tolerance and Autoimmunity: T Cells 8. Regulatory T Cells 9. B Cells and Autoimmunity 10. Immunological memory T cells 11. Immunological memory B cells 12. Apoptotic Cells as a Source of Autoantigens 13. Effector Mechanisms of Autoimmunity: Antibodies and Immune Complexes 14. Functional Effects of Autoantibodies 15. Cytokine Chemokines 16. Signaling Pathways in T and B Lymphocytes 17. HLA Genetics and Autoimmunity 18. Non HLA Genetics 19. AIRE related Autoimmunity 20. Immune Deficiencies and Autoimmunity 21. Infections and Autoimmunity 22. Noninfectious Environmental Agents and Autoimmunity 23. Sex, Pregnancy and Autoimmunity 24. Animal Models of Autoimmune Disease Section 2: Multisystem Diseases 25. Systemic Lupus Erythematosus 26. Systemic Sclerosis, Scleroderma 27. Antiphospholipid Syndrome 28. Sjogren Syndrome 29. Rheumatoid Arthritis 30. Spondyloarthritis and Chronic Idiopathic Arthropathies 31. Myositis 32. Thyroid Disease 33. Type 1 Diabetes 34. Adrenalitis 35. Polyendocrine Syndromes 36. Gastritis and Pernicious Anemia 37. Hypophysitis 38. Hemolytic Anemia 39. Thrombocytopenic Purpura 40. Neutropenia 41. Aplastic Anemia 42. Clotting Disorders 43. Multiple Sclerosis 44. Peripheral Neuropathy 45. Myasthenia Gravis 46. Ocular Disease 47. Inner Ear Disease 48. Celiac Disease 49. Inflammatory Bowel Diseases: Ulcerative Colitis and Crohn’s Disease 50. Chronic Hepatitis 51. Primary Billiary Cirrhosis 52. Primary Sclerosing Cholangitis 53. Pancreatitis 54. Bullous Skin Diseases: Pemphigus and Pemphigoid 55. Non-Bullous Skin Diseases: Alopecia, Vitiligo, Psoriasis and Urticaria 56. Kidney Disease: Goodpasture’s Disease, Lupus Nephritis, ANCA-Associated Glomerulonephritis 57. Orchitis and Male Infertility 58. Oophoritis 59. Rheumatic Heart Disease 60. Myocarditis and Dilated Cardiomyopathy 61. Necrotizing Arteritis and Small Vessel Vasculitis 62. Large and Medium Vessel Vasculitides 63. Autoimmune Disorders of the Lung 64. Paraneoplastic Diseases 65. Antibody-Associated Neurological Diseases 66. Autoinflammatory and other Related Diseases Section 3: Diagnosis, Prevention, and Therapy 67. Autoantibody Assays, Testing, and Standardization 68. Prediction of Autoimmune Disease 69. Emerging Therapies for Autoimmune Diseases 70. Postlude

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