Immunology Books

Book SynopsisTable of Contents1. Cardiovascular pathology: guide to practice and training L. MAXIMILIAN BUJA, BIHONG ZHAO, ANA SEGURA, LAURA LELENWA, MICHELLE MCDONALD AND KATARZYNA MICHAUD 2. Anatomic considerations and examination of cardiovascular specimens (excluding devices) J.J. MALESZEWSKI, C.K. LAI, VIDHYA NAIR AND JOHN P. VEINOT 3. Age-related cardiovascular changes and diseases ATSUKO SEKI AND MICHAEL C. FISHBEIN 4. Fundamental principles in cardiovascular genetics MICHAEL A. SEIDMAN AND RICHARD NEAL MITCHELL 5. Pathophysiology of heart failure and an overview of therapies M.J. RANEK, J.M. BERTHIAUME, J.A. KIRK, R.C. LYON, F. SHEIKH, B.C. JENSEN, B.D. HOIT, J. BUTANY, M. TOLEND, V. RAO AND MONTE S. WILLIS 6. Congenital heart disease: pathology, natural history, and interventions GIULIA OTTAVIANI AND L. MAXIMILIAN BUJA 7. Vascular pathobiology atherosclerosis and large vessel disease QUINN A. BONAFIGLIA, MICHELLE BENDECK AND AVRUM I. GOTLIEB 8. Diseases of small and medium-sized blood vessels JAMES R. STONE 9. Aneurysms of the aorta: ascending, thoracic, and abdominal and their management RENU VIRMANI, YU SATO, ATSUSHI SAKAMOTO, MARIA E. ROMERO AND JAGDISH BUTANY 10. Myocardial ischemia and its complications GREGORY A. FISHBEIN, MICHAEL C. FISHBEIN, JESSICAWANG AND L. MAXIMILIAN BUJA 11. Pathology of sudden death, cardiac arrhythmias, and conduction system GAETANO THIENE, S. RIZZO AND C. BASSO 12. Toxins and the heart RYAN P. LAU AND MICHAEL C. FISHBEIN 13. Myocarditis MICHAEL A. SEIDMAN AND BRUCE MCMANUS 14. Cardiomyopathies GIULIA D’AMATI AND C. GIORDANO 15. The pericardium and its diseases SUSAN M. ARMSTRONG, P. THAVENDIRANATHAN AND J. BUTANY 16. Valvular heart disease PRADEEP VAIDEESWAR, JAGDISH BUTANY AND SARANYA SINGARAVEL 17. Cardiac valve replacement and related interventions J. BUTANY AND F.J. SCHOEN 18. The pathology of cardiovascular interventions and devices for coronary artery disease, vascular disease, heart failure, and arrhythmias L. MAXIMILIAN BUJA AND FRED J. SCHOEN 19. Tumors of the cardiovascular system, heart, and blood vessels MARIA E. ROMERO, YU SATO, MASAYUKI MORI AND RENU VIRMANI 20. Pathology of cardiac transplantation E. RENE RODRIGUEZ, CELESTE SANTOS-MARTINS AND CARMELA D. TAN 21. Basic pathobiology of cell-based therapies and cardiac regenerative medicine L. MAXIMILIAN BUJA AND RICHARD N. MITCHELL 22. Forensic aspects of cardiovascular pathology BARBARA SAMPSONA, J. HAMMERS AND MICHELLE STRAMA

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Book SynopsisAMR is arguably one of the most severe long-term threats to human, animal, and environmental health. There is momentum for global political action around novel and emerging disease threats and Steering Against Superbugs contributes with original and insightful research to inform ongoing and future debates.Trade ReviewThis volume collects together key insights from across social sciences on AMR governance. AMR is now the third-leading underlying cause of death globally, which is why a global approach and global governance is necessary. Through a global perspective, the case studies in this volume highlight both successes and challenges of local, regional, and global governance for AMR. As we work together across the world to tackle the 'silent' AMR pandemic, I strongly recommend this book for all in the global and public health and policy sphere to help galvanise action to address the insidious and complex health emergency of AMR. * Professor Dame Sally Davies, UK Special Envoy on Antimicrobial Resistance (AMR) *Steering Against Superbugs comprehensively unpacks the root social drivers of antimicrobial resistance and masterfully situates these drivers in their cultural, historical and political contexts. Rubin, Baekkeskov, and Munkholm have brought together some of the world's leading thinkers in this field and have pro¬vided us with some of the best ideas yet to tackle this intensifying global health challenge that already kills more than 1.2 million people each year. * Professor Steven J. Hoffman, Director of the Global Strategy Lab and the WHO Collaborating Centre on Global Governance of Antimicrobial Resistance, York University, Canada *This exciting volume achieves what many have been waiting for: a compen¬dium of social science approaches to antimicrobial resistance. With a focus on governance, the authors demonstrate the strengths of different disciplines by providing evidence at multiple scales of the ways in which antibiotics, and drug resistance, is-and can be-governed. From clinics, to bednets, to global policy spaces, the book introduces the reader to detailed case studies that enlighten and awaken interest in the multiple dimensions that make up the complex challenge of antimicrobial resistance globally. * Professor Clare Chandler, Anthropology of Antimicrobial Resistance lead and founding Director, AMR Centre, London School of Hygiene & Tropical Medicine. *Microbes, humans, One Health, and the interplay between them through AMR. This book introduces the reader to the conceptual issues of AMR, and then steers her through governance challenges, One Health aspects, global awareness, advocacy and regulatory matters. This is essential reading, not just for those working in this critical field but also for policy- makers, healthcare leaders, One Health professionals, and the wider community-providing an armament of knowledge, insight, and perspectives in the fight against AMR. * Professor & Head Sujith J Chandy, Department of Pharmacology & Clinical Pharmacology, Christian Medical College Vellore, India *Table of Contents1: Steering against Superbugs: Research agenda and four perspectives for global governance Part I: Framing and conceptualizing AMR 2: Pills and Politics - a historical analysis of international antibiotic regulation since 1945 3: Global eradicationism and AMR 4: Conceptualizing AMR as a creeping disaster in terms of pace and space Part II: Coordination and leadership in AMR governance 5: Combatting AMR in the EU - governmental dimensions 6: Contested governance of collective action against AMR in the EU 7: What would it take to move the global AMR agenda forward in the Global South? Part III: AMR Governance from below 8: The individual in global and national AMR governance 9: Governing AMR: a case for considering governance 10: A sociological look beyond the surface of the national action plans against AMR: How state professionals adjust to global governance Part IV: A One Health Perspective on AMR 11: One Health and AMR governance 12: From policy to practice: Challenges and opportunities for cross-sectoral AMR mitigation and response efforts 13: Joint action against AMR with a One Health perspective Part V: Global advocacy and awareness of AMR 14: Policy entrepreneurship and problem brokering in the global governance of AMR 15: Global attention to Antimicrobial Resistance and Climate Change in the era of Social Media 16: The policy context for responses to antimicrobial resistance in India Part VI: Regulatory responses to AMR 17: A case for the global governance of AMR by regulating the pharmaceutical supply chain 18: Sustainable procurement of pharmaceuticals - a tool to combat global antimicrobial resistance 19: International Law and AMR: Learning from 15 years implementing the International Health Regulations

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Book SynopsisIn this volume, the authors describe a rational and evidence-based approach to the integrative therapy of rheumatologic, allergic, and autoimmune disorders, integrating the principles of alternative and complementary therapies into the principles and practice of conventional medical therapy. The authors examine what works and what doesn''t and offer practical guidelines for physicians for incorporating integrative medicine into their practice and advising patients on reasonable and effective therapies. The text discusses areas of controversy and identifies areas of uncertainty where future research is needed. Chapters cite the best available evidence for both safety and efficacy of all therapies discussed. Information will be presented in accessible and easy-to-read formats, including clinical pearls, case histories, and key points, with a second text color for highlighting key information.Trade ReviewThis beautifully produced volume was not only a pleasure to handle but also a real pleasure to read. * International Musculoskeletal Medicine *

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Book SynopsisIn Defense of Self introduces some of most important medical advances of the past hundred years, from the development of vaccines and the treatment of allergies, autoimmunity and cancer, to prolonging organ transplants and combating AIDS. It not only explains how a vital part of our bodies works, but also provides background for continuing research.Table of ContentsPART I: HOW THE IMMUNE SYSTEM WORKS; PART II THE IMMUNE SYSTEM IN HEALTH AND DISEASE

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Book SynopsisTrade ReviewThis book is useful for general neurologists for review on the wards and in clinic, as well as neuroimmunologists. * Tzu-Ying Chuang, MD, PhD, (Thomas Jefferson University), DOODY'S *Table of ContentsSection I CNS Demyelinating Disease (Cases 1-21) Case 1 A Woman With Subacute Painful Vision Loss Jiraporn Jitprapaikulsan, MD, M. Tariq Bhatti, MD, Eric R. Eggenberger, DO, and Marie D. Acierno, MD Case 2 Rapidly Progressive Numbness and Weakness After Soft-Tissue Abscess Elia Sechi, MD, and Dean M. Wingerchuk, MD Case 3 Weakness With Neck Flexion Brian G. Weinshenker, MD Case 4 New-Onset Right-Sided Numbness and Double Vision W. Oliver Tobin, MB, BCh, BAO, PhD Case 5 Progressive Left Lower Extremity Weakness and Thoracic Spinal Cord Lesion B. Mark Keegan, MD Case 6 Progressive Spasticity With a Single Magnetic Resonance Imaging Lesion Samantha A. Banks, MD, and Eoin P. Flanagan, MB, BCh Case 7 Fluctuating Vision Loss, Seizures, and Left Parieto-Occipital Mass Alicja Kalinowska-Lyszczarz, MD, PhD, W. Oliver Tobin, MB, BCh, BAO, PhD, Yong Guo, MD, PhD, and Claudia F. Lucchinetti, MD Case 8 Diffuse Pain and Abnormal Brain MRI Findings Andrew McKeon, MB, BCh, MD Case 9 Lesions Found by Chance Dean M. Wingerchuk, MD Case 10 Encephalopathy and Quadriparesis After an Upper Respiratory Tract Infection A. Sebastian Lopez Chiriboga, MD Case 11 Severe Monocular Vision Loss Followed by Gait Difficulty Brian G. Weinshenker, MD Case 12 Multiple Sclerosis and Cognitive Impairment Cristina Valencia-Sanchez, MD, PhD, and Jonathan L. Carter, MD Case 13 New-Onset Gait Difficulty With Kappa Free Light Chains in Cerebrospinal Fluid Maria Alice V. Willrich, PhD, and Ruba S. Saadeh Case 14 A Girl With Back Pain, Paresthesias, and Painful Vision Loss Cecilia Zivelonghi, MD, and Andrew McKeon, MB, BCh, MD Case 15 A Septuagenarian With Progressive Hemiparesis Roman Kassa, MD, and B. Mark Keegan, MD Case 16 Recurrent Demyelinating Episodes I. Vanessa Marin Collazo, MD Case 17 Breakthrough Disease While on Multiple Sclerosis Immunomodulatory Therapy Jonathan L. Carter, MD Case 18 Highly Active Multiple Sclerosis Roman Kassa, MD, and W. Oliver Tobin, MB, BCh, BAO, PhD Case 19 Progressive Gait Difficulties I. Vanessa Marin Collazo, MD Case 20 Progressive Cerebellar Ataxia After Natalizumab Treatment Michel Toledano, MD Case 21 Weakness and Dysarthria After Radiosurgery Andrew McKeon, MB, ChB, MD Section II Autoimmune Neurologic Disorders (Cases 22-52) Case 22 Fatigue, Blurry Vision, and Swollen Optic Nerves Marie D. Acierno, MD, M. Tariq Bhatti, MD, John J. Chen, MD, PhD, and Eric R. Eggenberger, DO Case 23 Progressive, Symmetrical, Painless Visual Loss in an Elderly Woman Eric R. Eggenberger, DO, Marie D. Acierno, MD, M. Tariq Bhatti, MD, and John J. Chen, MD, PhD Case 24 Personality Changes, Cognitive Decline, and Jerking Movements A. Sebastian Lopez Chiriboga, MD Case 25 Rapidly Progressive Memory Loss, Mood Change, Mutism, and Abnormal Movements Shailee S. Shah, MD, and Marie F. Grill, MD Case 26 Behavioral and Cognitive Changes Followed by Coma Anastasia Zekeridou, MD, PhD Case 27 Episodic Hemiparesis, Cognitive Decline, and Seizures in a Woman With Pernicious Anemia Cristina Valencia-Sanchez, MD, PhD, and Andrew McKeon, MB, BCh, MD Case 28 Rapidly Progressive Dementia and Thyroid Antibodies Amy C. Kunchok, MBBS, MMED, and Eoin P. Flanagan, MB, BCh Case 29 Goosebumps and Memory Loss Jeffrey W. Britton, MD, Bhavya Narapureddy, MBBS, and Divyanshu Dubey, MBBS Case 30 A Patient With Headache and Progressive Tremor Anastasia Zekeridou, MD Case 31 A Man With Flulike Symptoms and Hemorrhagic Brain Lesions Michel Toledano, MD Case 32 Hearing Loss, Imbalance, and Diplopia in a 44-Year-Old Man Michelle F. Devine, MD, Divyanshu Dubey, MBBS, and Sean J. Pittock, MD Case 33 Chorea, Ataxia, and Disturbed Sleep John C. Feemster, and Erik K. St. Louis, MD, MS Case 34 Rapidly Progressive Gait and Coordination Difficulties Andrew McKeon, MB, BCh, MD Case 35 Dancelike Movements in a Patient With a History of Rash Andrew McKeon, MB, BCh, MD Case 36 Body Spasms in a Woman With Thyroid Disease Andrew McKeon, MB, BCh, MD Case 37 Stiffness, Spasms, and Frequent Falls in a 41-Year-Old Man Michelle Devine, MD, and A. Sebastian Lopez Chiriboga, MD Case 38 Rapid-Onset Weakness and Numbness in a Patient With Systemic Lupus Erythematosus Floranne C. Ernste, MD Case 39 Progressive Quadriparesis and Cancer Elia Sechi, MD, and Eoin P. Flanagan, MB, BCh Case 40 Progressive Numbness, Burning Pain, Imbalance, and Dryness Shahar Shelly, MD, and Divyanshu Dubey, MBBS Case 41 Ascending Painful Paresthesias, Progressive Ataxia, and Bilateral Foot Drop Rocio Vazquez Do Campo, MD, and Divyanshu Dubey, MBBS Case 42 Painless, Symmetric, Ascending Weakness and Sensory Loss Christopher J. Klein, MD Case 43 Difficult-to-Treat Polyradiculoneuropathy Marcus V. R. Pinto, MD, MS, and P. James B. Dyck, MD Case 44 Autoimmune Peripheral Nervous System Hyperexcitability Christopher J. Klein, MD Case 45 Orthostatism, Constipation, and Early Satiety Kamal Shouman, MD, and Eduardo E. Benarroch, MD Case 46 Constipation and Syncope Michelle F. Devine, MD, and Sean J. Pittock, MD Case 47 Bulbar-Predominant Weakness Jennifer A. Tracy, MD, and Vanda A. Lennon, MD, PhD Case 48 Difficulty Climbing the Stairs Anastasia Zekeridou, MD, PhD, and Vanda A. Lennon, MD, PhD Case 49 Rapidly Progressive Proximal Weakness Teerin Liewluck, MD, and Margherita Milone, MD, PhD Case 50 Progressive Weakness and Rash Margherita Milone, MD, PhD, and Teerin Liewluck, MD Case 51 "Restlessness" After Cancer Diagnosis and Treatment Anastasia Zekeridou, MD, PhD Case 52 Sudden Onset of Diplopia and a Skeletal Muscle Antibody John R. Mills, PhD Section III Other Inflammatory CNS Disorders and Neuroimmunologic Mimics (Cases 53-83) Case 53 Diplopia, Orbital Pain, and Vision Loss in a Middle-Aged Woman Lauren M. Webb, and Eoin P. Flanagan, MB, BCh Case 54 A Young Man With Visual Field Loss, Decreased Hearing, and Confusion M. Tariq Bhatti, MD, Eric R. Eggenberger, DO, Marie D. Acierno, MD, and John J. Chen, MD, PhD Case 55 A Woman With Progressive Gait Difficulty and White Matter Abnormalities Adrian Budhram, MD, and Ralitza H. Gavrilova, MD Case 56 Progressive Asymmetrical Limb Impairment and Cognitive Decline With Leukoencephalopathy B. Mark Keegan, MD Case 57 A Woman With Fever, Confusion, and Seizures Michel Toledano, MD Case 58 Encephalopathy With Alternating Hemispheric MRI Abnormalities Andrew McKeon, MB, BCh, MD Case 59 Rapid-Onset Hemibody Sensory Loss, Incoordination, and Muscle Jerking Andrew McKeon, MB, BCh, MD, and Nicholas L. Zalewski, MD Case 60 A History of Sarcoidosis and a New Brain Lesion Andrew McKeon, MB, BCh, MD, and Julie E. Hammack, MD Case 61 Headache and Hemiparesis in Middle Age Catalina Sanchez Alvarez, MD, and Kenneth J. Warrington, MD Case 62 Subacute Cognitive Decline in an 86-Year-Old Woman With Prior Lobar Intracerebral Hemorrhage Stephen W. English Jr, MD, MBA, and James P. Klaas, MD Case 63 A 75-Year-Old Man With 5 Days of Progressive Gait Difficulties and Confusion Julie E. Hammack, MD Case 64 Night Sweats and Paraparesis David N. Abarbanel, MD, and Ivan D. Carabenciov, MD Case 65 A Woman With Headaches and a Tumefactive Brain Lesion Andrew McKeon, MB, BCh, MD Case 66 Behavioral Change, Seizures, and Temporal Lobe Lesion Stuart J. McCarter, MD, and Andrew McKeon, MB, BCh, MD Case 67 A Young Woman With Vessel Dissection and Brainstem Lesions Burcu Zeydan, MD, and Orhun H. Kantarci, MD Case 68 Headache, Uveitis, and Leptomeningeal Enhancement Orhun H. Kantarci, MD Case 69 Weakness and Punctate Enhancement W. Oliver Tobin, MB, BCh, BAO, PhD Case 70 Bilateral Paresthesias in Crohn Disease Amy C. Kunchok, MBBS, and Andrew McKeon, MB, BCh, MD Case 71 Seizures and Enhancing Brain Lesions Josephe Archie Honorat, MD, PhD, and Andrew McKeon, MB, BCh, MD Case 72 A Man With Recurrent Headache and Focal Neurologic Deficits Jaclyn R. Duvall, MD, and Jerry W. Swanson, MD, MHPE Case 73 Headache, Radicular Pain, and Enhancing Lesions W. Oliver Tobin, MB, BCh, BAO, PhD Case 74 Seizures 3 Months After Endarterectomy Andrew McKeon, MB, BCh, MD, and Robert D. Brown Jr, MD, MPH Case 75 Progressive Bilateral Arm Pain, Gait Disturbance, Constipation, and Urinary Retention Ivan D. Carabenciov, MD, and Michael W. Ruff, MD Case 76 A Woman With Subacute Numbness of the Trunk, Arms, and Legs Eoin P. Flanagan, MB, BCh Case 77 A Septuagenarian With Progressive Lower Extremity Weakness and Pain Nicholas L. Zalewski, MD Case 78 Acute Quadriparesis in a Smoker Nicholas L. Zalewski, MD Case 79 A 25-Year-Old Man With Recurrent Back Pain and Rapid-Onset Paraplegia Nicholas L. Zalewski, MD Case 80 Progressive Myelopathy After Neck Pain Eoin P. Flanagan, MB, BCh Case 81 Progressive Imbalance and Visual Impairment in a Patient With Diabetes Neeraj Kumar, MD Case 82 Progressive Myelopathy After Spine Surgery Andrew McKeon, MB, BCh, MD, and Nicholas L. Zalewski, MD Case 83 Altered Mental Status During the COVID-19 Pandemic Sara Mariotto, MD, Silvia Bozzetti, Maria Elena De Rui, Fulvia Mazzaferri, Andrew McKeon, MB, BCh, MD, and Sergio Ferrari Section IV Questions and Answers Section I: Questions, Answers, Suggested Reading Section II: Questions, Answers, Suggested Reading Section III: Questions, Answers, Suggested Reading

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Book SynopsisSjögren's Syndrome summarises current understanding of the pathogenesis of the disease, including advances in the genetics, disease mechanisms, clinical diagnosis and assessment, secondary Sjögren's syndrome, and the role of laboratory investigations and imaging.Trade ReviewThe volume contains well written, succinct, and comprehensive chapters on disease mechanisms, diagnosis, assessments, and laboratory investigations. The layout is pleasing, and each chapter has key points highlighted at the beginning. Chapters are easy to read with useful subheadings and plenty of summary tables and figures showing important mechanisms and pathways of care. This book is indispensable for all interested and involved in the care of the patients with Sjögren's syndrome. * Dr. Vinod Ravindran, Indian Journal of Rheumatology *

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Book SynopsisIn 'The Inflamed Feeling' Mats Lekander explores the science behind how you perceive your own health, using visual illusions, personal experiences, placebo, hypochondriacs, and historical anecdotes. Placed against a backdrop of the latest psychoneuroimmunology, he explores why you might feel healthy or why you might feel sickTrade ReviewJoin a thriller-like journey between body and brain, a constantly ongoing tourism in your innermost, in which balance and just as often unbalance is described in an accessible scientific way. Instructive and fun! * Barbo Osher, philanthropist and Consul-General of Sweden in San Francisco *At last a book about the psychology and physiology of well-being, giving fascinating insights into questions about health which takes up so much room in contemporary society * Martin Ingvar, author and Professor of Integrative Medicine at the Karolinska Institutet, Sweden *This is a great read for those wanting a very readable insight into our inner world. Incorporating insights from psychoneuroimmunology, Mats Lekander gives us a personal tour of the way the brain experiences both our outer and inner worlds. The author includes anecdotes of his personal experiences, making the field very accessible to non-specialists as well as highly accomplished scientists * Benjamin Hart, Distinguished Professor Emeritus at the University of California, USA *A fascinating journey drawing together cognitive psychology, anthropology, sociology and immunology to reveal how perceptions or misperceptions of our inner world (body) impact on our health and wellbeing. A must read! * Neil Harrison, Clinical Professor in Neuroimaging at Cardiff University, UK *Despite major advances in understanding the human immune system over the past few decades, one area that remains mysterious is the intersection between the immune system and other body systems. Among the latter, the nervous system has long been understood to have significant effects on the immune response, and puzzling out the current state of knowledge in this area is the focus of this intriguing book. Lekander (Stockholm Univ., Karolinska Institute) expertly blends current immunological and psychological research with clinical vignettes in a highly readable account. * Choice *Table of Contents1: What does the brain know about the outside world 2: What does the brain know about the body 3: Our inner defence systems 4: The sickness response 5: Disgust and prejudice in disease defence 6: How do you rate your general health 7: Feeling sick and other emotions 8: Can you affect your perceived health? 9: How society affects our health 10: Perhaps its not that bad?

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Book SynopsisThis practical pocketbook provides an overview of the role of HPV in the pathophysiology of cervical cancer and its current screening and management, the principles of immune control of HPV infection in cervical cancer, and the challenges of implementing HPV vaccines and future developments.Table of Contents1. The UK cervical screening programme ; 2. Management of cervical intraepithelial neoplasia (CIN) ; 3. Role of HPV in cervical carcinogenesis ; 4. HPV and genital cancer: the essential epidemiology ; 5. The role of HPV testing in cervical screening ; 6. Natural immune control of HPV infection ; 7. Prophylactic HPV vaccines: pre-clinical and proof of principle studies ; 8. Prophylactic HPV vaccination: current status ; 9. Introduction of HPV prophylactic vaccination ; 10. HPV vaccination in the developing world ; 11. Screening post vaccination ; 12. Second-generation HPV prophylactic vaccines ; 13. Therapeutic HPV vaccines ; 14. Conclusion

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Book SynopsisGives a perfectly balanced overview of the field, describing the key infectious agents our bodies encounter and how our immune system responds to them. It also explains how diseases are spread and what measures we can take to control this spread, from vaccination to increasing public awareness.Trade ReviewInfectious disease affects everyone. If you are hoping to understand the mechanism of infections and immunity at an introductory level, then you will find this an excellent reference book: my copy is well thumbed and already sports a forest of bookmarks. * Susan Omar, The Biologist *Table of ContentsTHE INFECTIOUS ORGANISMS; THE IMMUNE SYSTEM; THE HOST-PATHOGEN BALANCE

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Book SynopsisBiomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible.The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Clinical Immunology gives the new biomedical scientist an insight into the function of the immune system, the fTrade ReviewReview from previous edition The main strength is the description of the methods used in a laboratory setting. This is a unique feature and makes it stand out from other textbooks in the area. * Dr Fiona L. Henriquez, University of the West of Scotland *Using case studies really helps to integrate knowledge in an applied context. Students not only get to understand what is happening, but they begin to see why this is important, how this can affect the patient, and what it could mean to them in the diagnostic laboratory. * Glenn Hussey, Keele University *This excellent book would be particularly useful for undergraduates aiming to enter a career in biomedical science, and also a worthwhile read for trainee and practising biomedical scientists. * Immunology News *Table of Contents1. Introduction to the clinical immunology laboratory ; 2. Immunoglobulins ; 3. Allergy ; 4. Complement ; 5. Autoimmune rheumatological disease ; 6. Autoimmune kidney disease ; 7. Organ specific autoimmunity ; 8. Autoimmune skin disorders ; 9. Autoimmune liver disease ; 10. Neuroimmunology ; 11. Flow cytometry and primary immunodeficiency ; 12. Human immunodeficiency virus (HIV) ; 13. Histocompatibility and immunogenetics

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Trade Review"An eye-opening tour de force of scientific writing that reads like the best kind of adventure story. As David Attenborough opens our goggling eyes to the natural world without, so Davis brings us face to face with the stunningly clever and, yes, beautiful world within--our immune system. One of those books that makes you look at everything human in a new, challenging, and thrilling way."--Stephen Fry "Brilliantly conveys the excitement of scientific discovery."--Bill Bryson "Davis deftly sketches the history of immune science and the surprising discoveries made by scientists who were initially ridiculed by their peers--the man who first named interferon, an antiviral agent in the blood, was met with disbelief by colleagues who jokingly called it 'misinterpreton.' Today, scientists are successfully tinkering with our natural immune response in the molecular equivalent of taking the brakes off, so that our hunter-killer cells launch war against tumors."-- "Telegraph, Best Books of 2018" "Gives extraordinary new details of an ancient remedy that is already more marvelous, powerful, and flexible than any medicine to come out of a lab."--Roger Highfield "The human body is the most complicated assemblage of chemicals in the known universe. It's a huge scientific challenge to understand how we metabolize, how we acquire immunity, and how drugs work. Daniel Davis is a distinguished expert in this field--and he's a fine writer too. He portrays vividly how great discoveries emerge--via prolonged effort, via cooperation and competition, and sometime sheer luck. This gripping book gives an authentic flavor of how science is actually done--and why it's important for humanity's future."--Martin Rees "This book is an insight into new, remarkable, and almost unnoticed advances in immunology and shows how medicine is moving on from the world of the gene to the world of the antibody."--Steve Jones "A layman's introduction to the current state of the science of immunology. It is not an easy read, not because Davis is wilfully obscure but because his subject matter is extremely complex. Explanations should be as clear as possible, but not clearer than possible."--Anthony Daniels "Literary Review" "An inspirational book that not only reveals the 'secret joys' of scientific discovery but is jam-packed full of revelations for non-scientists."--Jon Dennis "Mail on Sunday" "Davis came to immunology from physics and, like visions of outer space, his picture of the human immune system--the little we actually know of it--is dizzying, intriguing, and strange. . . . Emphasizing that 'no scientist is an island, ' Davis follows the strings of achievements and failures (always at least as valuable as the successes) that have led to radical reinterpretations of how the immune system works. His explanations are rich in technical detail, but always clear: as he recreates the revelatory moments in the labs, he puts the reader right there at the microscope, on the edge of discovery. I was surprised how quickly I became (temporarily) fluent in the language of dendritic cells, receptors, cytokines, and so on. Davis also clearly defines more familiar terms such as interferons and interleukins, explains cortisol's effects and how it's related to cortisone, and flags the truly revolutionary insights in this history of sometimes baffling eureka moments."--Laurie G. "Politics and Prose, Staff Picks" "Davis endeavors to tell the story of human immunology in eight chapters, spanning foundational concepts, pivotal discoveries by brilliant scientists and their collaborators, the personal drama that has accompanied Nobel prizes and other recognition awarded in this highly competitive field, and anecdotes about how individual choices can affect one's immune function and overall health. . . . A heroic effort. . . . The relatively brief overview reveals intriguing connections in immunology's history, helps tie together stove-piped areas of inquiry, and offers fresh perspective on future research strategies."--Audrey R. Glynn "Science" "Davis is a sure and engaging guide to these developments. . . . In each case, Davis shows how these scientific thinkers overturned the previous dogma and progressively deepened the story of immunology. His message is that although knowledge of the immune system has come on in leaps and bounds in the past hundred years, immunology still lacks a unifying theory. 'We must not expect everything the immune system does to fit any one over-arching principle, ' he concludes. 'The system discriminates between self and non-self, and it detects germs, and it responds to danger, and it does all these things concurrently--and messily.'"--Mark Honigsbaum "Observer" "Detailed and fascinating."--Emma Stoye "Chemistry World" "Five stars. We all think we know, at a rough level, how the immune system works. Cells in the blood identify foreign invaders and go into battle with them. Inflammation and perhaps a fever develop, and eventually the body destroys the illegal immigrants. From then on their card is marked: the system remembers the microscopic terrorists, and if they ever reappear they are ganged up on and eliminated immediately. That's immunity. In recent decades, though, the scientific picture has become hugely more complicated, as the immunologist Davis relates in this elegantly concise book."--Steven Poole "Telegraph" "Forget AI, robotics, the internet of things. This is where the future feels strange and exciting: in ourselves, in the 'inner universe' of our messy, complex immune system, and in the radically new therapies that are using it to conquer disease. Davis is passionate about the possibilities of his field. . . . He describes how these cells perform with the fervor of an enraptured dance critic. . . . Davis is right to call the immune system an inner universe. It is just as consciousness-raising and awe-inspiring as the outer universe of black holes and supernovas, yet far less widely known or understood. This eye-opening if demanding book starts to put that right."--James McConnachie "Sunday Times" "Refreshingly sober. . . . Intelligent and insightful."--Jerome Groopman "New York Review of Books" "Davis's wonderful book The Beautiful Cure recounts how research into the immune system in recent decades has resulted in what amounts to a health revolution. Immunotherapy drugs are now worth billions of dollars, and cancers and autoimmune diseases that were once considered untreatable can now be fought and, in a few cases, even cured. There is little doubt that there will be further progress in the years to come. Davis recounts in exceptionally clear and sympathetic prose how all this came about."--Henry Marsh "New Statesman" "A terrific book by a consummate storyteller and scientific expert considers the past and future of the body's ability to fight disease and heal itself. . . . We should all pay more attention to understanding the barricades that evolution has provided us with, that we have learned to train, because this war is endless. The Beautiful Cure is a worthy guide."--Adam Rutherford "Guardian" "The Beautiful Cure sets the stage for a coming revolution in immunology, with fascinating stories of how researchers solved puzzles they didn't know existed."--Jeremy Webb "New Scientist" "The Beautiful Cure is about the history and future of immunology. It is a sweeping tour d'horizon that never shies from complexity but manages, impressively for a science book by a scientist, to remain lucid and entertaining enough to take the reader with it. Much as Siddhartha Mukherjee did in his book The Gene, Davis expertly weaves together human stories and scientific endeavor to give a sense of the grand global collaboration that is still under way to understand 'the complexity, delicacy, and elegance of our immune system.' . . . If anything can be taken from this book it is that life and its mechanisms are too complex for neat stories, however satisfying those stories may be."--Tom Whipple "Times" "The Beautiful Cure . . . focuses on the science of immunology itself, taking us through the evolution of the discipline and the stories behind key advances in the field. . . . Davis conveys a visceral appreciation for how messy, and how human, medical science can be."--David A. Shaywitz "Wall Street Journal" "Davis leaves readers with a reminder that, for all the scientific innovations described here, the human immune system remains 'far more powerful than any medicine we have devised, ' and that sleep, healthy eating, mindfulness, and other complementary practices all appear to help. A modern equivalent of Paul de Kruif's 1926 classic, Microbe Hunters, Davis's work is concise and illuminating."-- "Publishers Weekly" "Davis is a leading immunologist himself and writes gracefully about a subject he knows well, brings alive not only the science, but the scientists themselves, many of whom he knows personally. The Beautiful Cure will give you a new appreciation for the marvels of our biology."-- "Medium"Table of ContentsA note to professional scientists Overview PART ONE: The Scientific Revolution in Immunity 1 Dirty Little Secrets 2 The Alarm Cell 3 Restraint and Control 4 A Multibillion-Dollar Blockbuster PART TWO: The Galaxy Within 5 Fever, Stress and the Power of the Mind 6 Time and Space 7 The Guardian Cells 8 Future Medicines Epilogue Acknowledgements Notes Index

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Book Synopsis''Thrilling, inspiring and informative page-turner.'' Walter Isaacson, author of The Code BreakerYou know what went wrong.This is the untold story of what went right.Few were ready when a mysterious respiratory illness emerged in Wuhan, China, in January 2020. Politicians, government officials, business leaders and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world''s biggest drug and vaccine makers were slow to react or couldn''t muster an effective response.It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist resented by his peers. Far from the limelight, each had spent years developing innovatTrade ReviewThe race to develop a COVID vaccine is one of the most exciting dramas in medical history, and A Shot to Save the World is a thrilling account based on great reporting and access to all of the teams. An inspiring and informative page-turner. * Walter Isaacson, author of The Code Breaker *An appropriately breathless account of the business and scientific rivalries between researchers and companies behind the successful coronavirus vaccines. Zuckerman shows how a global catastrophe transformed the fortunes of tiny, visionary ventures, and huge pharmaceutical enterprises, as they raced to stem the pandemic's spread. -- Andrew Hill * Financial Times *Zuckerman conveys decades of complex scientific research in a gripping fashion. His focus on the slow burn of discovery makes for a fascinating angle and offers plenty of inspiration. The result is tough to put down. * Publishers Weekly *

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Book SynopsisPsychoneuroimmunology is the first textbook to examine the complex functional relationships between the nervous system, the neuroendocrine and the immune system. The international leaders in this field have been brought together to create this pioneering text; each contributing from their area of expertise. The result is a comprehensive yet accessible interdisciplinary introduction to psychoneuroimmunology which also takes you further than the foundations of those fascinating topics by covering the most recent research in HIV/AIDS, autoimmune diseases, and the reactivation of latent herpes viruses. Attention is also given to the effects of behavior such as physical exercise, sleep, acute and chronic stress, and conditioning of immune functions in animals and humans. The whole is brought together with a wealth of cited research studies, and over 200 illuTable of Contents1.Functional Anatomy of the Immune System; J. Westermann, M.S. Exton. 2.Foundations in Immunology; R. Jacobs, R.E. Schmidt. 3.Principles of Endocrinology; T. H. Schürmeyer, E. J. Wickings. 4.Concepts in Psychology; U.Tewes. 5 Psychological Methods; U.Tewes, M. Schedlowski. 6.Endocrinological Methods; T. H. Schürmeyer, E. J. Wickings. 7.Methods in Immunology; R. Jacobs. 8. Molecular Anatomical Basis of Interactions between Nervous and Immune Systems in Health and Disease; E. Weihe, et al. 9.Neuroendocrine System and Immune Functions; M. Schedlowski, R. J. Benschop. 10. Opioid Peptide Production by the Immune System; C. J. Heijnen, A. Kavelaars. 11.The Immune-Neuroendocrine Network; H. O. Besedovsky, A. del Rey. 12.Sickness Behavior: A Neuroimmune-Based Response to Infectious Disease; R. Dantzer. 13.Stress Effects on Immune Function in Rodents; M. K. Demetrikopoulos, et al. 14.Behavior/Immune Relationships in Nonhuman Primates; M. L. Laudenslager, J. M. Worlein. 15.Acute Psychological Stress; R. J. Benshop, M. Schedlowski. 16.Concepts and Models of Immunological Change during Prolonged Stress; C. L. Coe. 17.Does Psychological Depression Cause Immune Suppression in Humans? M. Irwin, E. Friedman. 18.Exercise and Immune Functions; B. Klarlund Pedersen. 19.Biobehavioral Influences on Respiratory Immunity; J. Kugler. 20.Effects of PsychosocialInterventions on the Immune System; M. E. Kemeny, G. Miller. 21.Sleep and Immune Functions; J. Born. 22.Functional Relationship between the Olfactory and Immune Systems; F. Eggert, R. Ferstl. 23.Behavioral Conditioning of Immunity; M. S. Exton, et al. 24.Psychoneuroimmunology in Oncology; D. H. Bovbjerg, et al. 25.Psychoneuroimmunology and HIV/AIDS; N. Schneiderman, et al. 26.Psychoneuroimmunology and Autoimmune Diseases; A. Kavelaars, et al. 27.The Effects of Stress on the Immune System: Implications for Reactivation of Latent Herpesviruses; K. L. Applegate, et al. References. Index

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book SynopsisTrade ReviewDoody's Core Titles® 2022 "This book covers diagnosis and management of allergic diseases with emphasis on new therapies. Primary care providers and other specialists who care for allergic patients will find this collection a valuable reference book." ©Doody's Review Service, 2022, Massoud Mahmoudi, DO, PhD (University of California San Francisco)Table of ContentsTentative: 1 Introduction to Mechanisms of Allergic Disease 2 Origins of Allergic Disease 3 Epidemiology of Allergic Disease 4 Indoor and Outdoor Allergens and Pollutants 5 Principles of Allergy Diagnosis 6 Allergen-Specific Immunotherapy 7 Asthma 8 Allergic Rhinitis and Conjunctivitis 9 Drug Allergy 10 Urticaria and Angioedema Without Wheals 11 Atopic Dermatitis and Allergic Contact Dermatitis 12 Food Allergy and Gastrointestinal Syndromes 13 Anaphalaxis 14 Occupational Allergy 15 Insect Allergy

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Book SynopsisTable of Contents1. Introduction Part 1: Mechanisms of Autoimmunity induction by infectious agents and vaccination 2. Molecular Mimicry and Autoimmunity 3. Epitope Spreading in Autoimmune Diseases 4. The immune neuroendocrine system, infections, and rheumatic diseases 5. CD5-Expressing B-1 Cells and Infection 6. Lymphocytes and Infection in Autoimmune Diseases 7. Endothelial Cell Autoreactivity and Infection 8. Microbiota and Autoimmunity 9. Infection, Autoimmunity, and Vitamin D 10. Seasonality and Autoimmunity 11. The Protective Role of Helminths in Autoimmunity 12. Vaccination and Autoimmunity 13. BCG Vaccination 14. Opportunistic Infections and Autoimmune Diseases 15. Can Antibiotics Cure Autoimmune Diseases? Part 2: Viruses and Autoimmunity 16. Anti-Viral Therapy, Epstein–Barr Virus, Autoimmunity, and Chaos (The Butterfly Effect) 17. Roles for Cytomegalovirus in Infection, Inflammation, and Autoimmunity 18. Hepatitis C and Mixed Cryoglobulinemia: An Update 19. HIV Spectrum and Autoimmune Diseases 20. Parvovirus Infection and Its Association with Autoimmune Diseases 21. Human T-lymphotropic Virus Type 1 and Rheumatic Diseases: A Link Between Infection and Autoimmunity 22. Sjögren’s Syndrome: Role of Viruses and Viral-Like Sequences 23. Viral Infection and Heart Disease: Autoimmune Mechanisms 24. Celiac Disease and Rotavirus Infection 25. Theiler’s Murine Encephalomyelitis Virus-Induced Demyelinating Disease (TMEV-IDD) and Autoimmunity Part 3: Bacteria and Autoimmunity 26. Rheumatic Fever: How Streptococcal Throat Infection Triggers an Autoimmune Disease 27. Helicobacter pylori Infection and Gastric Autoimmunity: Coincidence or a Cause and Effect Relationship? 28. Multiple Sclerosis and Creutzfeldt–Jakob Disease are Autoimmune Diseases Probably Caused by Exposure to the Nasal Microbe Acinetobacter 29. Infection and Autoimmunity in Antibiotic-Refractory Lyme Arthritis 30. Streptococcus Pneumoniae and Autoimmunity: A Systematic Review of the Literature: How Pneumococcal Infection Might Be Related to Rheumatic Diseases 31. Mycobacteria and Autoimmunity 32. Mycobacterium avium Subspecies Paratuberculosis and Human Disease: Bridging Infection and Autoimmunity 33. Leprosy and Autoimmunity Part 4: Parasites and autoimmunity 34. Parasitic Infection and Autoimmunity 35. Toxoplasma and Autoimmunity 36. Malaria and Systemic Lupus Erythematosus: Complex Interactions and Reciprocal Influences Part 5: Autoimmune diseases and infections 37. Anti-Saccharomyces cerevisiae Antibodies Autoimmune Diseases 38. The Infectious Origin of the Anti-Phospholipid Syndrome 39. Infections and Systemic Lupus Erythematosus 40. Infections and Idiopathic Inflammatory Myopathies 41. Rheumatoid Arthritis and Infections: More Than an Association? 42. Infection and Systemic Sclerosis 43. Infection and Spondyloarthropathies 44. Infection and Behçet Disease 45. Vasculitides and Hepatitis C Infection 46. The Role of Infection in Inflammatory Bowel Disease: Initiation, Exacerbation and Protection 47. Post-Infectious Arthritis and Reactive Arthritis 48. Infection and Autoimmune Liver Diseases 49. The Role of infection in Immune-mediated Thrombocytopenia 50. Viral Infections and Type 1 Diabetes 51. Infection and Autoimmune Thyroid Diseases 52. Pemphigus and Infection 53. Infections and Autoimmune Renal Diseases 54. Infections Associated with Retinal Autoimmunity 55. Oral Infections and Autoimmune Diseases 56. infection and Guillain–Barré Syndrome 57. Acute Disseminated Encephalomyelitis Part 6: COVID-19 and autoimmunity SARS-CoV-2 (COVID-19) and Autoimmunity 58. COVID-19 and autoimmunity 59. COVID-19 and autoantibodies 60. COVID-19 and vasculitis 61. COVID-19 vaccines and autoimmunity

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Book SynopsisVaccines are a debate, whether we want them to be or not. Now more than ever, it''s easy to feel overwhelmed by the accusations and arguments that bloom across the news and internet.With a blend of science and history, HOW VACCINES WORK demystifies the strange and intricate world of vaccines: it explains what a vaccine is, how they are discovered and developed, and what happens when they meet our bodies.With over two decades of experience as an immunologist, David Miles gives expert insight into each vaccine routinely used in Britain, how they have kept us healthy, and why many people have come to worry about possible side effects. Through thrilling storytelling and in-depth exploration of the most common vaccination myths, HOW VACCINES WORK is the perfect guide to understanding all the vaccines we currently receive.Trade ReviewA very good combination of the history of current vaccines and an explanation of what they do and how they do it. As a book for the lay public it is exceptional and I would recommend it to any prospective vaccine recipient or parent -- Stanley A Plotkin, Emeritus Professor of Pediatrics, University of Pennsylvania

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Book SynopsisAn essential guide to optimising your immunity and feeling your best - all year roundThousands of us are struck down by colds, flu and other viruses every year. We know we should be taking steps to look after our immune system every day, but beyond taking vitamin C and getting a good night''s sleep it''s often difficult to know where to start.In How to Stay Healthy, registered nutritionist Jenna Hope provides an easy-to-follow guide that will show you the steps you need to take to optimise your immunity and feel at your best.Through well-explained science this book will help you to understand what the immune system is, why it is so important and how to keep it functioning well in a way that suits you. It will cover the impact of nutrition, gut health and the role of supplements on your immune system, as well as lifestyle factors including smoking, physical activity, sleep, stress and pollution. Hope''s smart, simple and sustainable approach will show you easy ways to incorporate immunity friendly foods into your diet, quick tips for when you''re feeling run down and guidance to set you on the road to recovery from illness.Looking after your immune system has never been more important. This book provides the expert advice you need to do just that.

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Book SynopsisCase Studies in Infectious Disease presents 40 case studies featuring the most important human infectious diseases worldwide. Fully revised and updated in this second edition, the book describes the natural history of infection from point of entry of the pathogen through to clinical management of the resulting disease or condition. A further 8 case studies have been provided online as supplementary material, and these can be downloaded by students. Five core sets of questions are posed in each case, with the answers covering the nature of the infectious agent, route(s) of spread and of infection, pathogenesis of disease, host response to infection, clinical manifestations, diagnosis, treatment and prevention. This standardized approach provides the reader with a logical basis for understanding these diverse and medically important organisms and diseases, fully integrating microbiology and immunology throughout.KEY FEATURES High-resolution photos accompany each case, from the causative agents of disease to the clinical manifestations of the infection. Exquisite artwork helps to illustrate important concepts throughout the book. Eight new cases added to this new edition, extending coverage of important infectious diseases of worldwide significance. A standardized set of core questions allows students to compare directly differences between microbes such as their structure, clinical manifestations, host response, pathogenesis and availability of vaccines. Questions and answers available online, test the readerâs understanding of each case study. The book provides essential case-based learning for undergraduate and graduate microbiology students, while medical students and trainee physicians will also find the up-to-date information on 48 globally important infectious diseases outlined in a clear, digestible form, invaluable during undergraduate studies and in future clinical practice. Trade Review"a handsome, excellent book on most common pathogens, with a clear orientation to immunology, physiopathology, and microbiology … It reads well and is an excellent textbook for medical students and a good source of illustrations, tables, and question ideas for teachers." Gary P. Wormser and Guillaume Béraud for Clinical Infectious Diseases."a valuable compilation of information on the most common diseases that cause illness and death worldwide. The presentation format with distinct sections makes it readable and well suited for either students just learning about the pathogens causing infectious disease or clinicians who need an update. The level of detail is well thought out and gives the reader a useful summary of each pathogen and disease state. The condensed presentations make it a good reference source for those with insufficient time to read through more detailed textbooks." Philip S. Brachman for Emerging Infectious Disease.Table of ContentsAspergillus fumigatus Borrelia burgdorferi and related species Campylobacter jejuni Candida albicansChlamydia trachomatis Clostridiodies difficile Cytomegalovirus Echinococcus spp. EnterovirusesEpstein-Barr virus Escherichia coli Giardia lamblia Helicobacter pylori Hepatitis B virus Hepatitis C virusHerpes simplex virus Histoplasma capsulatum Human immunodeficiency virus Influenza virus Leishmania spp. Leptospira spp. Listeria monocytogenes Mycobacterium leprae Mycobacterium tuberculosis Neisseria gonorrhoeae Neisseria meningitidis Norovirus Plasmodium spp. Respiratory syncytial virus Rickettsia spp. Salmonella typhi Schistosoma spp. Staphylococcus aureus Streptococcus pneumoniae Streptococcus pyogenes Toxoplasma gondii Trypanosoma spp.Trichophyton spp. and dermatophytesVaricella-zoster virus Wuchereria bancrofti Plus online cases:Bartonella bacilliformis BrucellaCoxiella burnetti Dengue virusEnterococcus faecalis and E. faeciumMycobacterium abscessusSARS-CoV-2 Streptococcus mitis

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Book SynopsisA NEW YORK TIMES BESTSELLERFINALIST FOR THE 2022 NATIONAL BOOK AWARD FOR NONFICTIONNamed one of the BEST BOOKS OF 2022 by NPR, The New Yorker, Time, and Vogue“Remarkable.” –Andrew Solomon, The New York Times Book ReviewAt once a rigorous work of scholarship and a radical act of empathy.”—EsquireA ray of light into those isolated cocoons of darkness that, at one time or another, may afflict us all.” —The Wall Street JournalEssential.—The Boston GlobeA landmark exploration of one of the most consequential and mysterious issues of our time: the rise of chronic illness and autoimmune diseasesA silent epidemic of chronic illnesses afflicts tens of millions of Americans: these are diseases that are poorly understood, frequently marginalized, and can go undiagnosed and unr

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Book SynopsisAn introductory overview of the immunology of cancer including therapeutic approaches, this book will be an invaluable source for clinicians, researchers and students of immunology and molecular biology.Table of ContentsIntroduction. Immune Recognition of Cancer-Tumor Antigens. Processing and Presentation of Antigen for the Activation of Lymphocytes. Cellular Recognition of Tumors by T and NK Cells. Humoral Recognition of Cancer. Immunotherapy of Cancer. Tumor Evasion of Immune System.

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Book SynopsisFrom diagnostic tools to therapy against cancer, infections and autoimmune diseases, antibodies serve many purposes, yet our knowledge of them is still incomplete. The Antibodies: Volume 7 continues with a comprehensive review of topics of contemporary interest including major breakthroughs such as the advent of monoclonal antibodies and the development of new techniques of antibody engineering that have kept antibodies at the forefront of immunology and medical science. While examining the ground-breaking discoveries of the last two decades this book also revisits more traditional aspects of the field to give an holistic approach to this increasingly popular area of medicine.Table of ContentsPositive Selection of B Cell Repertoire, Idiotype Networks and Immunological Memory. The Utility of Immunoglobulins Fusions in DNA Immunisation. Constraints on the Hydropathicity and Sequence Composition of HCDR3 are Conserved Across Evolution. Molecular Aspects of Anti-Polysaccharide Antibody Responses. Molecular Farming Antibodies in Plants: From Antibody Engineering to Antibody Production.

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