Description
Book SynopsisThis book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide organ system–based summaries of spontaneous pathology and common responses to xenobiotics. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 1, Immunobiology, Investigative Techniques, and Special Studies, offers an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays.
These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system.
Trade Review“The purpose is to provide organ system-based summaries of spontaneous pathology and common responses to xenobiotics. … used as a textbook or reference for students, as an informative resource for novices in the field, and as a reference for researchers in the immune toxicology field. It also can be educational for the lay public who are interested in learning immunopathology in xenobiotics or general basic immunology. … a terrific book that I will certainly integrate into my graduate teaching.” (Hongmin Ni, Doody's Book Reviews, November, 2017)
Table of ContentsThymus.- Spleen.- Lymph node.- Mucosa-associated lymphoid tissues.- Immunopathology of the nervous system.- Immunopathology of the urinary system.- Immunopathology of the hepatobiliary system.- Immunopathology of the respiratory system.- Immunopathology of the cardiovascular system.- Immunopathology of the male reproductive tract.- Immunopathology of the female reproductive tract and mammary gland.- Immunopathology of the musculoskeletal system.- Immunopathology of the endocrine system.- Ocular Immunopathology.- Immunopathology of Drug and Toxin-related Skin Reactions.
