Medical parasitology Books

Book SynopsisFully revised for its third edition, the Oxford Handbook of Expedition and Wilderness Medicine continues to be the essential resource for all expedition medics and well-informed travellers, as well as nurses, paramedics, medical students, and other expedition members travelling in remote, wilderness areas of the world. Now containing more guidance about caving medicine, the third edition includes revised and additional illustrations and essential maps of the spread of diseases. Clear and concise, readers can rely on this handbook to provide the key knowledge and practical advice they need. It enables efficient preparation and planning before the journey, advises on camp logistics, risk management, and medical problems during the expedition, as well as highlighting rare but important risks to those visiting remote areas. Focusing on preventative measures, it also contains chapters dealing with crisis management, emergency care, and evacuation from challenging environments, with guidance about the obligations of a clinician joining an expedition, ethical approaches to such work, and medicine in various extreme environments. This edition will give you the confidence and skills you need to travel to any extreme or remote environment. Incorporating the combined knowledge and experience of a team of experienced clinicians and expeditioners, this is a practical, easy-to-use guide to all aspects of expedition and wilderness medicine.Table of Contents1: Expedition medicine 2: Preparations 3: Caring for people in the field 4: Ethics and responsibilities 5: Crisis management 6: Emergencies: diagnosis 7: Emergencies: trauma 8: Emergencies: collapse and serious illness 9: Treatment: skin 10: Treatment: head and neck 11: Treatment: dental 12: Treatment: chest 13: Treatment: abdomen 14: Treatment: limbs and back 15: Treatment: infectious diseases 16: Psychological and psychiatric problems 17: Risks from animals 18: Plants and fungi 19: Anaesthesia in remote locations 20: Cold climates 21: Mountains and high altitude 22: Inland and coastal waters 23: Offshore 24: Underwater 25: Hot, dry environments: deserts 26: Hot, humid environments: tropical forest 27: Caving 28: Medical kits

Read more less

Book SynopsisThe new edition of this unique handbook continues to provide an accessible and comprehensive, signs-and-symptoms based source of information on medical problems commonly seen in the tropics. A practical guide to diagnosis and management for medical practitioners and students, it provides vital information at the reader's fingertips.Trade ReviewThis is a highly useful handbook for clinicians in tropical disease environments. The topics are presented with tremendousclarity and economy of language. * Kenneth Schaefle, MD (Albert Einstein College of Medicine), Doody's *Review from previous edition This book presents information in a simple manner combined with updated current knowledge, making it a useful adjunct for its intended readers. * BMA Book Awards 2014. Highly Commended *This is a useful resource for healthcare providers who work in limited-resource settings and/or in tropical areas. * Doody's *Overall, this book is well written, easy to read and practical, providing easy access to crucial information, from common problems to rare diseases. * Dipti Patel , Occupational Medicine Book Review *Table of Contents1: Management of the sick child 2: Malaria 3: HIV medicine 4: Tuberculosis 5: Chest medicine 6: Gastroenterology 7: Cardiovascular 8: Renal Medicine 9: Neurology 10: Haematology 11: Endocrine disorders 12: Ophthalmology 13: Dermatology 14: Bone, joint and soft tissue infections 15: Sexually Transmitted Infections 16: Nutrition 17: Multi-system diseases and infections 18: Mental health 19: Trauma 20: Poisoning and envenoming 21: Immunization 22: Health emergencies in humanitarian crises 23: Obstetric emergencies 24: Healthcare-associated infection, antimicrobial prescribing, and antimicrobial resistance

Read more less

Book SynopsisThe 4th edition of this book provides laboratory staff and clinicians with a quick benchtop reference on the identification and antifungal susceptibility of human and animal fungal infections. It contains descriptions of all the major medical fungal pathogens, 179 species from 109 genera. This updated edition includes new and revised descriptions and he authors have reconciled current morphological descriptions and name changes with more recent genetic data. The most common fungal species are described, including members of the yeasts, mucoromycetes, conidial moulds, dimorphic pathogens, and dermatophytes. The book features:updates to taxonomy and fungal names.more than 350 colour photographs. antifungal susceptibility profiles, including for new drugs where available.methods of identification including molecular and/or MALDI-ToF mass spectroscopy.This handy reference is essential for laboratory staff and clinicians dealing with the identification and management of human and animal fungal infections, researchers in medical microbiology and mycology laboratories.

Read more less

Book SynopsisTrade Review"A well-organized, -researched, and -illustrated overview of the parasitic world."---Tina Panik, Library Journal"[An] approachable and often fascinating primer on the subject."---Jerome Groopman, The New Yorker"[A] fascinating book. . . . you won’t look at parasites in the same way again."---Gege Li, New Scientist"[A] world-ranging study."---Andrew Robinson, Nature"Engrossing and well-illustrated. . . .A very readable, interesting, and well-presented introduction to the often overlooked evolutionary and ecological aspects of host-parasite interactions"---Leon Vlieger, The Inquisitive Biologist"Recommended."---D.A. Brass, Choice"The stories narrated by Gardner et al. are truly informative. . . . [If] you are looking for a new way to explore the planet, look no further than the microscopic, and sometimes macroscopic, world of parasites."---Francisco C. Ferreira, The Quarterly Review of Biology

Read more less

Book SynopsisTable of Contents1. Symbiosis and Parasitism 2. Parasite-Host Interactions Part I: The Protozoa 3. General Characteristics of the Euprotista (Protozoa) 4. Visceral Protozoa I: (Amoebae) and Ciliophorans 5. Visceral Protozoa II: Flagellates 6. Blood and Tissue Protozoa I: Hemoflagellates 7. Blood and Tissue Protozoa II: Human Malaria 8. Blood and Tissue Protozoa III: Other Protists Part II: The Trematoda 9. General Characteristics of the Trematoda 10. Visceral Flukes 11. Blood Flukes Part III: The Cestoda 12. General Characteristics of the Cestoda 13. Intestinal Tapeworms 14. Extraintestinal Tapeworms Part IV: The Nematoda 15. General Characteristics of the Nematoda 16. Intestinal Nematodes 17. Blood and Tissue Nematodes Part V: Arthropoda 18. Arthropods as Vectors Appendix A. Drugs for Parasitic Infections: Partial List of Generic and Name Brands B. Current Chemotherapeutic Regiments C. Adverse Effects of Antiparasitic Drugs

Read more less

Book SynopsisTable of Contents1. The structural organization of the cytoskeleton of Giardia 2. Microtubule organelles in Giardia 3. Recent Advances in Functional Research in Giardia duodenalis 4. Proteomics and transcriptomics of Giardia-epithelial cell-interactions 5. Pathogenesis and post-infectious complications of giardiasis 6. Drug Resistance in Giardia: Mechanisms and Alternative Treatments for Giardiasis

Read more less

Book SynopsisDescribes what a doctor can do if she/he cannot refer a patient, both in emergency and for 'cold surgery'. This work includes common problems such as Caesarean section, the resection of dead gut, and the release of pus from infected bones. It describes the organization and equipment found within an operating theatre.Trade ReviewIt is clear, thorough, well cross-referenced and deals with equipment and the organisation of the theatre, as well as with procedures themselves... almost certainly the best and most comprehensive text on surgery in developing countries. * Africa Health *Table of ContentsThe background to surgery; Theatres, antiseptics, and antibiotics; The control of bleeding; Basic methods and instruments; The surgery of sepsis: draining abscesses; Pus in the pleura, the pericardium, the peritoneum, and the pelvis; Pus in the muscles, bones and joints; Pus in the hands and feet; Methods for abdominal surgery; The acute abdomen: intestinal obstruction; The stomach; The appendix; The gall-bladder, pancreas, and spleen; Hernias; The surgery of conception; The surgery of pregnancy; The medicine of pregnancy; The surgery of labour; Other obstetric problems; Gynaecology; The breast and the thyroid; Proctology; Urology; The eye; The ear, nose, and throat; The teeth and mouth; Orthopaedics; Paediatric surgery; Surgery, AIDS, and hepatitis B; The surgery of tubercolosis; The surgery of leprosy; The surgery of `tropical' diseases; Oncology; Terminal care; Miscellaneous; Appendices.

Read more less

Book SynopsisTrade ReviewA well-written and fascinating introduction to human parasitology from an intriguing, seldom-used perspective: how we can learn from parasites to achieve medical breakthroughs. -- Rod Adam, University of Arizona Dickson D. Despommier's approach is unique, easy going, and insightful. His book will appeal to both scientists and laypeople interested in science and medicine-and will be of particular interest to travelers to exotic places. -- Robert Gwadz, National Institutes of Health There's a lot to learn from a tapeworm. Parasites have evolved stunningly successful strategies for thriving in our bodies for millions of years. Drawing on his long career as a parasitologist, Dickson D. Despommier explores the lessons we can gain from our passengers, creating a fascinating tour of the parasitic world. -- Carl Zimmer, author of A Planet of Viruses and Parasite Rex [An] illuminating book... Despommier is an excellent popularizer, lacing his accounts of our invaders' ingenuity with history and anecdotes that underscore how grateful a modern society should be for clean drinking water and sanitary facilities. Kirkus Reviews Reading this book may make your skin crawl... The facts are horrifying and fascinating... As Despommier argues, these body snatchers deserve respect. -- Marissa Fessenden Scientific American [People, Parasites, and Plowshares] chronicles the discovery-and destructive treachery-of parasites as well as the promise they offer modern medicine in curing a number of diseases. Washington Post [People, Parasites, and Plowshares] beautifully balances history and pathology. -- Dave Lee Discover A rich, fulsome feast. It is also a gift to tropical medicine. American Journal of Tropical Medicine An informative and entertaining view of parasitic life cycles and resulting human diseases... The use of illustrations, examples, and stories, combined with limited use of technical terms, works well to connect and engage the reader... Highly recommended. CHOICE Despommier's writing is precise, clear, and up to date... I highly recommend this book to anyone interested in parasitology. -- Scott L. Gardner BioScience A smoothly crafted mix of pathology, public and global health, how these parasites make their livings, and fascinating stories. -- Janice Moore BioScienceTable of ContentsForeword by William C. Campbell Preface Acknowledgments 1. This New House: Trichinalla spiralis 2. Hooked on Parasites: Ancylostoma duodenale and Necator americanus 3. Houdini's Nefarious Cousins: The Trypanosomes, the Schistosomes, and the Lymphatic Filariae 4. A Parasite for All Seasons: Toxoplasma gondii 5. The Unholy Trinity: Ascaris lumbricoides, Trichuris trichiura, and the Hookworms 6. The Long and the Short of It: Tapeworms-Taenia saginata, Taenia solium, Diphyllobothrium latum, Echinococcus granulosus, and Echinococcus multilocularis 7. All's Well That Ends Wells: Dracunculus medinensis 8. Nature Has All the Answers. What's Your Question? Glossary Further Reading Index

Read more less

Book SynopsisWritten for the educated patient and health care provider, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. Brian A. Fallon and Jennifer Sotsky argue forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully.Trade ReviewLyme disease is a more complicated and nuanced illness than has been previously recognized. Fallon and Sotsky's experience with the neuropsychological manifestations of Lyme, combined with their insights into the current patient experience, make this book a significant addition to the literature. A well-organized, comprehensive treatment of Lyme disease and the associated issues that patients face. -- John Aucott, Johns Hopkins University School of Medicine, Lyme Disease Research CenterTable of ContentsAcknowledgmentsPreface Basic Terminology1. What Is Lyme Disease?2. The Early History and Epidemiologic Surveillance3. What Are the Symptoms and Signs of Lyme Disease?4. What Do the Diagnostic Tests Tell Us?5. The Great Divide and the Lyme Wars6. Why Would Symptoms Persist After Antibiotic Treatment?7. What Are the Treatments for Lyme Disease? 8. Other Tick-Borne Infections9. What Other Non-infectious Diseases Cause Lyme-Like Symptoms?10. Lyme Disease Prevention and Transmission11. Suggestions to the Patient Seeking Evaluation or Treatment12. The Experience of the Patient with Chronic Symptoms13. Frequently Asked Questions14. The Good News Emerging from Lyme Disease ResearchGeneric (Brand) Drug NamesGlossary of TermsReferencesIndex

Read more less

Book SynopsisWritten for the educated patient and health care provider, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. Brian A. Fallon and Jennifer Sotsky argue forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully.Trade ReviewA lucid and important book, filled with moving case histories and vignettes, about an infectious illness that is threatening many lives. -- Siddhartha Mukherjee, author of The Emperor of All Maladies: A Biography of Cancer and The Gene: An Intimate History Lyme disease is a more complicated and nuanced illness than has been previously recognized. Fallon and Sotsky’s experience with the neuropsychological manifestations of Lyme, combined with their insights into the current patient experience, make this book a significant addition to the literature. A well-organized, comprehensive treatment of Lyme disease and the associated issues that patients face. -- John Aucott, director, Johns Hopkins Lyme Disease Clinical Research CenterConquering Lyme Disease is a balanced and factual synthesis of what is known and unknown about Lyme disease. Written in a clear and understandable way for a lay audience as well as medical professionals, it is a rich source of information on this complex subject, explaining the science behind current treatments and future directions for research. -- Stephen W. Barthold, University of California, DavisAn enlightening, informative, and up-to-date account of the key issues surrounding the complexity, controversy, prevention, diagnosis and treatment of Lyme borreliosis, especially the persistent form of the disease. Written by an outstanding and well-respected physician with tremendous experience, Conquering Lyme Disease will help to bridge the great divide and offer new hope in our fight against this debilitating disease. A must read for all interested in Lyme and associated diseases. -- Ying Zhang, MD, Johns Hopkins University, Bloomberg School of Public HealthA sturdy reference on an illness whose varied presentations can bedevil patients and caregivers alike. * Publishers Weekly *In Conquering Lyme Disease, colleagues and coauthors Fallon and Sotsky push readers to grapple with some underlying scientific principles. Readers will have a better sense of where the research is today, where treatment falls short, and what the future may hold. * Library Journal *What is science’s role in turning the corner on what some have labelled a 'public health failure'? Physicians Brian Fallon and Jennifer Sotsky tackle this question in their insightful study Conquering Lyme Disease, in which they journey beyond the history, biology and symptoms of the illness. Their greatest accomplishment, by far, is delivering multiple viewpoints with minimal bias and great sensitivity: the clinician’s, the researcher’s and, particularly, the patient’s. -- James G. Logan * Nature *Highly suggested to everyone. -- Anna Maria Polidori * Articles and more... *By presenting an accessible, measured examination of the disease and synthesizing current research, the authors offer readers a great service...Highly recommended. * Choice *Fallon and colleagues have produced a valuable book combining humanistic Forster-type narratives and scientific Fisher-like elements to examine the human condition of chronic illness while describing current research in the complexities of Lyme disease. -- Paul Auwaerter * The Lancet Infectious Diseases *A timely new book. * CMRubinWorld *Table of ContentsAcknowledgmentsPreface Basic Terminology1. What Is Lyme Disease?2. The Early History and Epidemiologic Surveillance3. What Are the Symptoms and Signs of Lyme Disease?4. What Do the Diagnostic Tests Tell Us?5. The Great Divide and the Lyme Wars6. Why Would Symptoms Persist After Antibiotic Treatment?7. What Are the Treatments for Lyme Disease? 8. Other Tick-Borne Infections9. What Other Non-infectious Diseases Cause Lyme-Like Symptoms?10. Lyme Disease Prevention and Transmission11. Suggestions to the Patient Seeking Evaluation or Treatment12. The Experience of the Patient with Chronic Symptoms13. Frequently Asked Questions14. The Good News Emerging from Lyme Disease ResearchGeneric (Brand) Drug NamesGlossary of TermsReferencesIndex

Read more less

Book SynopsisThis is a thorough revision and update of the highly successful first edition, which which achieved sales in excess of 4,500. The text serves as a comprehensive introduction to parasitology for both undergraduate and beginning graduate students. In this edition, particular emphasis is placed on parasites of human and veterinary importance. The first three chapters in the text are concerned with how parasites ''work,'' their biochemistry, molecular and cell biology and physiology. The remaining chapters cover ecology and epidemiology, immunology and chemotherapy, with the final chapter covering integrated control. This new edition contains new material on cell and molecular biology, vectors and control, which is in contrast to the general biological approach of the first edition. The second edition will succeed the first as the major text on parasitology for students in biology, zoology, microbiology, medicine, veterinary medicine, tropical medicine and public health.Table of ContentsParasitic protozoa; Parasitic helminths; Vectors; Epidemiology; Biochemistry; Molecular biology and molecular genetics; Physiology and nutrition; Immunology; Chemotherapy; Control

Read more less

Book SynopsisSUITABLE FOR KINDLE AND OTHER EBOOK DEVICESSwitch off the news and mute your tense WhatsApp chats - here are 101 family-friendly, fun, smart, silly, useful, good-to-know things to do and learn that will take your mind off what''s going on outside the comfort of your own home, providing you with plenty of much needed moments of positivity and calm. Including (but not limited to!): Quizzes Anagrams Poems Riddles Jokes Word games Fun facts And other ways to occupy your time in a fulfilling way.Suitable for those aged 7 to 107, with the quizzes requiring some grown-up knowledge.And whilst you #StayHome, don''t miss these other great titles from Sphere Books:** The Bumper Book of Would You Rather? Over 350 hilarious hypothetical questions for ages 6 to 106 **** Home Sweet Home: The Little Book of Natural Cleaning **

Read more less

Book SynopsisIn this provocative collection of essays, François Delaporte shows how every epistemological concern demands its own mode of engagement. Through six seemingly disparate cases, Figures of Medicine reanimates the methodological and intellectual stakes at the core of the history of science and medicine.Trade Review"As always with Delaporte the scholarship is impressive, innovative and impeccable, and the analyses acute." -- -Camille Limoges Centre interuniversitaire de recherche sur la science et la technologie (CIRST-UQAM) Montreal "Lucid, focused, and rigorous ... An outstanding book that makes important contributions to intellectual history, the history of medicine, and their methodologies." -- -Jonathan Strauss Miami University

Read more less

Book SynopsisIn this provocative collection of essays, François Delaporte shows how every epistemological concern demands its own mode of engagement. Through six seemingly disparate cases, Figures of Medicine reanimates the methodological and intellectual stakes at the core of the history of science and medicine.Trade Review"As always with Delaporte the scholarship is impressive, innovative and impeccable, and the analyses acute." -- -Camille Limoges Centre interuniversitaire de recherche sur la science et la technologie (CIRST-UQAM) Montreal "Lucid, focused, and rigorous ... An outstanding book that makes important contributions to intellectual history, the history of medicine, and their methodologies." -- -Jonathan Strauss Miami University

Read more less

Book SynopsisParasitic flatworms include Cestodes (tapeworms) and trematodes (flukes, schistosomes, etc) and are the cause of a number of major diseases of medical and veterinary significance. Much recent research has focused on molecular biology and genomics. this book aims to review advances in our understanding of these and related topics such as flatworm biochemistry, immunology and physiology. Where appropriate, comparisons are made between different parasitic flatworms and between parasitic and free-living species. Contributors to the book include leading authorities from Europe, North and South America, and Australia.Table of ContentsPart I: Phylogeny, Genetics and Transcriptomes 1: The Evolution of Parasitism in Flatworms, D T J Littlewood, Natural History Museum, UK 2: Genomes and Genomics of Parasitic Flatworms, D A Johnston, Natural History Museum, UK 3: Genetic Discrimination of Echinococcus Species and Strains, D P McManus, University of Queensland, Australia 4: Ribosomal DNA Variation in Parasitic Flatworms, D Blair, James Cook University, Australia 5: Genetic Studies on Monogeneas with Emphasis on Gyrodactylus, ,CO Cunningham and I Matějusová, FRS MarineLaboratory, Aberdeen, UK 6: The Schistosome Transcriptome, S Verjovski-Almeida and R DeMarco, Universidade de Sao Paulo, Brazil 7: Transgenic Flatworms, C G Grevelding, Justus-Liebig-University Giessen, Germany Part II: Immunobiology, Host-Parasite Interaction and Control 8: Immunobiology of Schistosomes, S G Forrester, University of Ontario, Canada and E J Pearce, University of Pennsylvania, USA 9: Cestode Infection: Immunological Considerations From Host and Tapeworm Perspectives, D M McKay, McMaster University, and R A Webb, York University, Canada 10: Parasitic Flatworms: Signal Transduction at the Host-Parasite Interface, T P Yoshino, J J Vermeire and J Humphries, University of Wisconsin-Madison, USA 11: Parasite Effects on the Snail Host Transcriptome, M Knight and N Raghavan, Biomedical Research Institute, USA 12: Developments in the chemotherapy of parasitic flatworms, G C Coles, University of Bristol, UK 13: Drug Resistance in Schistosomes, T A Day, Iowa State University, USA and S Botros, Theodor Bilharz Research Institute, Egypt 14: Praziquantel: Mechanism of Action, R M Greenberg, Marine Biological Laboratory, Woods Hole, MA, USA 15: Cestode Vaccine Development, M W Lightowlers, University of Melbourne, Australia 16: The Development of a Schistosome Vaccine, R A Wilson and P S Coulson, University of York, UK Part III: Protein Function, Metabolism and Physiology 17: Flatworm Parasite Proteomics, R M Morphew, J Barrett and P M Brophy, University of Wales, UK 18: Proteases in Trematode Biology, J P Dalton, C R Caffrey, M Sajid, C Stack, S Donnelly, A Loukas, T Don, J McKerrow, D W Halton & P J Brindley. 19: Signalling Molecules and Nerve-Muscle Function, A G Maule, N J Marks and T A Day 20: Unusual Aspects of Metabolism in Flatworm Parasites, A G M Tielens and J J van Hellemond, Utrecht University, Netherlands 21: Glycoconjugate Structures, M Wuhrer, Leiden University Medical Center, Netherlands and R Geyer, University of Giessen, Germany 22: Gene Silencing in Flatworms using RNA interference, P J Skelly, TuftsUniversity School of Veterinary Medicine, USA"

Read more less

Book SynopsisA detailed account of the embryology, growth and metamorphosis of mosquitoes, the nutrition of larvae and adults, and egg production by the adult females. Physiological adaptations of larvae to their aquatic environment are also described. Written in a manner to be comprehensible to any informed biologist, the book has received glowing reviews.Table of Contents1: Aspects of genetics 2: Embryology 3: The egg shell 4: Larval feeding 5: Larval nutrition, excretion and respiration 6: Osmotic and ionic regulation 7: Growth and development 8: Metamorphosis 9: The circulatory system 10: The endocrine system and hormones 11: Adult food and feeding mechanisms 12: The adult salivary glands and their secretions 13: Structure of the adult alimentary canal 14: Adult digestion 15: Adult energy metabolism 16: Adult diuresis, excretion and defaecation 17: Structure of the gonads and gonoducts 18: Spermatogenesis and the structure of spermatozoa 19: Oogenesis 20: Vitellogenesis 21: Hormonal regulation of ovarian development in anautogenous mosquitoes 22: Nutrition and fertility of anautogenous mosquitoes 23: Autogeny -: Published by Chapman and Hall in 1992, this volume is now available from CABI Publishing

Read more less

Book SynopsisThis second edition of the popular advanced student textbook (previously published as Worms and Disease: A Manual of Medical Helminthology) has been thoroughly updated and revised since it was first published in 1975. It includes contributions and a chapter by Prof. Derek Wakelin, University of Nottingham, UK. An authoritative handbook covering all human helminth infections with particular emphasis on diagnosis, treatment, clinical manifestations, pathogenesis, epidemiology and control. Practical guidelines are given for estimating the clinical and public significance of helminthiases, vital in areas where the majority of inhabitants are infected with many helminths but only a few are sick.Table of Contents1: The Trematodes 2: The Cestodes 3: The Acanthocephalans 4: The Nematodes 5: Oher Groups 6: Immunology of Helminths 7: Epidemiological Aspects of Helminth Infections 8: Helminthological Techniques

Read more less

Book Synopsis

Read more less

Book SynopsisDespite numerous scientific investigations on vector-borne human infections such as malaria, Lyme disease and typhus these diseases continue to threaten human health. Understanding the role of vectors in disease transmission, and the most appropriate control strategies, is therefore essential. This book provides information on the recognition, biology, ecology and medical importance of the arthropods that affect human health. The fifth edition of this popular textbook is completely updated and incorporates the latest strategies for controlling insects, ticks and mites. Numerous illustrations, with new colour photographs of some of the most important vectors, aid recognition. A glossary of entomological and epidemiological terms is included, along with a list of commonly used insecticides and their trade names. Clearly presented in a concise style, this text is aimed at students of medical entomology, tropical medicine, parasitology and pest control. It is also essential reading for phyTrade ReviewReviews of the third edition: '… a very well written book that is well suited for its purpose as an introduction for students … it would serve well as a quick refresher to the subject even for experienced medical entomologists.' The Lancet'… undergraduate and postgraduate masters students can continue to rely on this affordable and reliable basic introduction to the discipline of medical entomology.' Parasitology'This is an easy to understand introduction to the field of medical entomology for more readers than just students of biology and entomology … [another] appropriate title might be 'Medical Entomology for Health Care Providers and Public Health Practitioners'.' Doody's Review Service'… a 'must have' for those studying the discipline … a continuing strength is its frequent updating cycle and the helpful addition and revision of the further reading section.' Richard D. Ward, Keele UniversityTable of ContentsPreface to the first edition; Preface to the second edition; Preface to the third edition; Preface to the fourth edition; Preface to the fifth edition; Acknowledgements; 1. Introduction to mosquitoes (Culicidae); 2. Anopheline mosquitoes (Anophelinae); 3. Culicine mosquitoes (Culicinae); 4. Black flies (Simuliidae); 5. Phlebotomine sand flies (Phlebotominae); 6. Biting midges (Ceratopogonidae); 7. Horse flies (Tabanidae); 8. Tsetse flies (Glossinidae); 9. House flies and stable flies (Muscidae) and latrine flies (Fanniidae); 10. Flies and myiasis; 11. Fleas (Siphonaptera); 12. Sucking lice (Anoplura); 13. Bedbugs (Cimicidae); 14. Triatomine bugs (Triatominae); 15. Cockroaches (Blattaria); 16. Soft ticks (Argasidae); 17. Hard ticks (Ixodidae); 18. Scabies mites (Sarcoptidae); 19. Scrub typhus mites (Trombiculidae); 20. Miscellaneous mites; Appendix: names of some chemicals and microbials used in vector control; Glossary of common terms relevant to medical entomology; Select bibliography; Index.

Read more less

Book Synopsis

Read more less

Book SynopsisAntibiotics have vastly changed the way we fight diseases. History is replete with examples of infectious diseases that have killed millions of people worldwide in the past and continues to do so in the present. However, there is one major difference. In the past there were novel classes of antibiotics that were being discovered at regular intervals, and in the present we are running out of options. Moreover, whatever antibiotics we have, microbes have developed resistance, which could primarily be attributed to the injudicious usage of antibiotics, not only for humans but also for veterinary purposes. A previous report from World Health Organization (WHO, 2017) suggests that antimicrobial resistance is a serious hazard and antibiotics under clinical development may not be sufficient (or efficient enough) to treat these emerging resistant pathogens. That report had identified 51 antibiotics and 11 biologicals. Of those, only 12 were found to be active against WHO classified critical priority pathogens and only two of them were found to be active against more than one specific pathogen. Starting with the sulphonamides in the 1930s to lipopeptides in the early 2000s, research and development on novel antibiotics is usually a slow and painful process and currently it will suffice to say that it is on the decline. As per the Infectious Diseases Society of America (IDSA), we are facing what is known as an antibiotic paradox that is pushing against the development of novel antibiotics. Interestingly, though there are studies that keep reporting on antibiotics, most of these are on combinatorial use of antibiotics. What could be their effectiveness and more importantly what could be their biotoxicity in the long run, remains unknown. Microbial antibiotic resistance is not a new phenomenon and there are numerous studies that have demonstrated the various mechanisms underlying it. An interesting study by Indian Council of Medical Research (ICMR), has shown that commensals in the gastrointestinal tract of humans might be responsible for the increasing ineffectiveness of antibiotics, at least in Indians. This makes it clear that microbes will keep on producing resistance to antibiotics at a faster rate compared to our ability to develop them. Under these circumstances, natural compounds, primarily plant-based, have become valuable tools and could be our answer to not only effective antimicrobial principles, but also to antimicrobial resistance. These compounds are abundant in nature and there is already a very rich literature on their usage and efficacy based on the various traditional systems of medicine. These natural compounds have been shown to be effective against both Gram positive and Gram-negative pathogens and interestingly microbes have a limited chance (as far as studies show) of developing resistance towards them. This is primarily attributed to the fact that most of these compounds are used as polyherbal formulations. Another advantage in studying these natural compounds is that there is a better probability of hitting upon that jackpot molecule or molecules for antimicrobial applications. Being relatively safe and inexpensive makes them very attractive areas for clinical research. This book, in line with others in the field, is a small attempt to highlight the developments related to the antimicrobial compounds from natural sources and their mechanisms of action, particularly against ESKAPE pathogens. This book, we believe, will serve as a small but important piece of source material for students and researchers interested in this particular area of research. The chapters are divided to showcase the relevance and importance of natural compounds as novel antimicrobials, inhibitors of antimicrobial resistance and immunomodulators and we hope that the topics will kindle the interest of young researchers in these lines. In the end, we are grateful and whole heartedly acknowledge the authors for their valuable contribution and reviewers for their valuable suggestions and critical review of the manuscripts.

Read more less

Book SynopsisEntamoeba: Species, Classification and Biology outlines the current knowledge about the global epidemiology, clinical manifestations, pathogenesis, available diagnostic tools and management of pathogenic Entamoeba species in humans. The authors provide an overview of the various species belonging to the genus Entamoeba, including Entamoeba histolytica, Entamoeba dispar, Entamoeba gingivalis, Entamoeba coli, Entamoeba moshkovskii, Entamoeba invadens, Entamoeba polecki, Entamoeba hartmanni, Entamoeba suis, Entamoeba nuttalli, Entamoeba bangladeshi, Entamoeba struthionis and Entamoeba muris. The general pathogenic factors of Entamoeba histolytica are described, particularly focusing on how these factors participate in establishing infection. Additionally, an review of studies centered on the morphological, biochemical and genetic changes during programmed cell death of Entamoeba histolytica is provided. Current knowledge on the identification, characterisation, structure, and function of the enzymes of serine biosynthesis is also summarized.Table of ContentsPreface; Pathogenic Intestinal Entamoeba Species in Humans: Epidemiology, Pathogenesis and Man-agement; Pathogenic and Non-Pathogenic Species of Entamoeba; Infection by Entamoeba Histolytica and Immunity against This Enteric Parasite; Programmed Cell Death (PCD) in Entamoeba histolytica; Structural and Functional Studies of Serine Biosynthetic Pathway Enzymes in E. histolytica; Index.

Read more less

Book SynopsisNeurocysticercosis, a preventable parasitic infection of the central nervous system caused by tapeworm, is a serious, potentially fatal disease that can cause neurologic syndromes such as epileptic seizures. Chapter One of this monograph describes the existing treatment options for neurocysticercosis, along with possible therapeutic alternatives under different drug development phases. Chapter Two explains the difficulties associated with correctly diagnosing neurocysticercosis, resulting from its varied clinical presentation, and mentions current guidelines of diagnostic criteria for neurocysticercosis. Chapter Three describes the various merits and demerits of techniques for detecting the parasites associated with neurocysticercosis, which include radioimaging, genotyping of cysts, and antibody, antigen, and nucleic acid detection in body fluids.Table of ContentsPreface; Treatment of Neurocysticercosis: Current and Future Options; The Challenge of Deciphering Certainty from Ambiguity for the Laboratory Diagnosis of Neurocysticercosis; Trends in the Diagnosis of Human Neurocysticercosis: Issues and Challenges; Index.

Read more less

Book Synopsis

Read more less

Book SynopsisParasitology is the study of parasites, their hosts, and the relationship between them. Many molecular tools have been developed over the past decades to determine genotypes and subgenotypes of parasites. This book describes the use of DNA technology in epidemiological investigations for parasitic research. During recent years, a striking number of studies also provided new insight into the cellular interactions and molecular mechanisms of malaria parasites during liver infection. This book summarises novel findings on the malaria liver stage biology. Furthermore, organ transplants have become more frequent world-wide. Unfortunately, parasitic infections can be transmissible by transplantation. The authors of this book describe the most useful methodology, as well as its application for the precise diagnosis of the parasite in the laboratory. The transmission mechanisms and the main factors of risk of each one of the parasites involved is discussed as well. Other chapters in this book examine the toxoplasma gondii, an intracellular protozoan parasite which infects potentially any warm-blooded animal, and the giardia duodenalis trophozoites, which have a remarkable ability to attach to the surface of epithelial cells of infected hosts. The various approaches that have been used to identify, isolate and characterise novel genes from the parasite genome of Babesia gibsoni are examined as well.

Read more less

Book Synopsis

Read more less

Book SynopsisThe book entitled "Schistosomiasis: Epidemiology, Diagnosis and Treatment", published by Nova Science Publishers Inc. presents a very interesting overview on this tropical parasitic disease in the post-genomic era. The book is a collection of 8 chapters written by world-renown health professionals and researchers, highly active in the field. The mainly targeted public is MDs specialising in Tropical Medicine as well as experienced Researchers and Professionals who are faced with the challenges of this ancient threat to human health. This book is conceptually divided into two sections: (1) a broad recollection of the up-to-date state of the comprehension of Schistosomiasis, including its interplay with the human host; (2) a focused survey on specific field studies, presenting the actual challenges of the disease. The first part, composed of 4 chapters, is preparatory to a better understanding of the case studies in the second part. Special attention has been put on three selected at risk categories of people: pre-school aged children, women, and travellers/migrants; the first two living in endemic areas, and the latter in non-endemic regions. In between these two sections is the chapter on zoonotic schistosomiasis, a neglected research area that shows the dangerous role of infected livestock in maintaining the disease in endemic countries.

Read more less

Book SynopsisHuman African trypanosomiasis or sleeping sickness is caused by infection with the morphologically indistinguishable subspecies Trypanosoma brucei rhodesiense (in East and Southern Africa) and Trypanosoma brucei gambiense (in West and Central Africa). The disease is presently almost under control and less than 4000 cases are currently reported. In both, T. b. rhodesiense and T. b. gambiense infection, after the injection of infective metacyclic trypanosomes with tsetse fly vector saliva, the parasites establish in the skin, differentiate to the bloodstream stage and spread via the local draining lymph node into the vascular system. In this book, Chapter One presents an overview of the current epidemiology, clinical features, diagnosis and treatment options. Chapter Two provides an in-depth review of diagnostic methods for African trypanosomiasis. Chapter Three discusses the use of aminoadamantane derivatives against Trypanosoma brucei.

Read more less

Book SynopsisFor human health, leishmaniasis is among the most important protozoan diseases, superseded only by malaria. Globally, 10 to 12 million people are infected with 1.5 million new cases every year. The development of cheaper new drugs is urgently needed for this neglected disease that is developing resistance to current treatments. Chemotherapy remains the only treatment option for the bulk of patients. However, this is largely unaffordable for most. In the past three years numerous advances in drug discovery have been made for treating this disease by exploiting diverging metabolic pathways between the Leishmania enzymes and their hosts, using nanotechnology to target the immune cell phagolysosomes where Leishmania resides. Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania. Recent studies have shown that leishmaniasis affects some of the poorest people in the world, with 95% of fatal cases occurring in only 6 countries. With the WHO goal of eliminating this public health problem in the South-east Asia Region by 2020, this book will be important for anyone who is interested in neglected tropical diseases.Trade ReviewThis is a timely and highly relevant book that provides a comprehensive and in-depth overview of the current state and future directions of drug discovery for leishmaniasis. It has a broad scientific scope and wonderful insights from leading experts in the field which ensures that there is something for everyone, and that this book is truly a must-have for anyone working in the area of leishmaniasis. -- Dr. Steven L. Cobb, Durham University (UK) * ChemMedChem, DOI: 10.1002/cmdc.201800266 *Table of ContentsLeishmaniasis, Impact and Therapeutic Needs; Anti-leishmanial Drug Discovery: Past, Present and Future Perspectives; From Bench to Bedside: Development and Optimization of Clinical Therapies for Visceral Leishmaniasis; Drug Assay Methodology in Leishmaniasis: From the Microplate to Image Analysis; The Pursuit of Novel Anti-leishmanial Agents by High-throughput Screening (HTS) of Chemical Libraries; Omics and Their Impact on the Development of Chemotherapy Against Leishmania; In silico Tools for Target Identification and Drug Molecular Docking in Leishmania; Medicinal Chemistry Strategies to Discover New Leishmanicidal Drugs; Natural Products as a Source of New Drugs Against Leishmania; Organometallic Compounds in Chemotherapy Against Leishmania; New Avenues for Drug Delivery in Leishmania: Using Treatment of Visceral Leishmaniasis with Amphotericin B as an Exemplar; Addressing the Molecular Biology of Leishmania for Drug Development; The Physical Matrix of the Plasma Membrane as a Target: The Charm of Drugs with Low Specificity; Nutrient Transport and Sensing as Pharmacological Targets for Leishmaniasis; Carbon Metabolism as a Drug Target in Leishmania; The Redox Metabolism and Oxidative Stress in Leishmania as a Crossroads for the Lethal Effect of Drugs; DNA Topoisomerases as Promising Targets for Leishmania Chemotherapy; Molecular Basis of Drug Resistance in Leishmania; The Macrophage–Parasite Interface as a Chemotherapeutic Target in Leishmaniasis

Read more less

Book SynopsisSchistosomiasis is Africa's second most common parasitic disease. Less than 20 years ago, over 200 million were infected. In many high-risk areas the Schistosomiasis Control Initiative (SCI) has been helping to tackle the disease by offering treatments to millions of children. This book tells the story of a man, Alan Fenwick, who founded the SCI to control the worms and snails and so improve the lives of many burdened with the disease as well as reducing the numbers infected. Over this period SCI and the Ministries of Health and Education in 16 countries delivered over 220 million treatments. Treatment coverage of up to 75% has been achieved. Widely recognised as a cost-effective and successful intervention, SCI's knock-on effects include improving overall physical health, school attendance and future prospects for millions of people. The authors explore the work and experiences involved in forming, establishing and managing a health intervention system such as the SCI, while describing important lessons for anyone looking to replicate the success. This book covers: - Challenges faced and how the SCI overcame them to achieve its success; - Raising funds to deliver donated medicines; - Development of innovative partnerships; - Cultivation of working relationships and implementation across Africa; - A new model for other Neglected Tropical Disease programmes (NTDs); - Aspects of Alan's life in Africa told with memorable and often humorous anecdotes. A Tale of a Man, a Worm and a Snail is an essential resource for researchers, policymakers, health professionals and students of NTD control. The book is an enlightening, informative and enjoyable read for anyone interested in global health.Table of ContentsChapter 1: My Early Years, My Education and My First Job Chapter 2: Schistosomiasis and the Amazing Life-cycle of a Killer Worm Chapter 3: Coming of Age in Tanzania – Arusha, 1966–1971 Chapter 4: Research, Training and Drug Testing in Sudan, 1971–1988 Chapter 5: Assisting the Control of Bilharzia in Egypt, 1988–2002 Chapter 6: An Ambitious Programme for Africa (from 2002) Chapter 7: Establishing SCI – The Early Days, 2002-2003 Chapter 8: The Big Three versus NTDs – Finding Common Purpose Chapter 9: Planning for Success Chapter 10: Across Borders - Implementing Schistosomiasis Control from East to West Africa Chapter 11: Schistosomiasis - Mapping the Disease Chapter 12: Drugs - Mobilising the African Marketplace to Paralyse the Worm Chapter 13: Advocacy and Promotion of SCI Activity Chapter 14: M&E – What is Measured and Reaching Out to Donors Chapter 15: Building Partnerships - High Stakes for High Rewards Chapter 16: The SCI Target - Low Infection Rates Chapter 17: Research - Forewarned is Forearmed Chapter 18: Recognition for SCI Work Chapter 19: Accelerating Control of NTDs and Schistosomiasis in Particular, 2008–2020 Chapter 20: The Last Mile Chapter 21: What Next for Alan?

Read more less

Book SynopsisParasites are a major issue affecting animal and human health, welfare, and economic productivity. This book provides 555 questions to test your knowledge of animal and tropical parasitology, to help you study anywhere, with any amount of time. Key features: Covers the most important and the most neglected parasites in a concise manner. Questions address parasite biology, epidemiology, diagnostics and management, all in relation to animal health. Includes key zoonotic parasites and their impact on human health. Uses multiple choice questions, true or false statements, fill-in-the-blanks, and more, to enable independent learning and self-testing. Provides explanatory answers to aid further revision and study. A self-test resource for veterinary and animal science students that is also of interest to medical students interested in parasitology or zoonoses, this book provides a convenient, useful, and current source of information to anyone interested in learning, revising and assessing their knowledge in parasitology.Table of Contents1: Multiple Choice Questions 2: Matching Questions 3: Fill-In-The-Blank Questions 4: True or False Questions 5: Image-Based Questions

Read more less

Book SynopsisToxocara is a parasitic helminth worm which continues to stimulate both public concern and scientific interest. Toxocara canis and T.cati, the most studied species, are gastrointestinal parasites of dogs and cats and their eggs can contaminate the environment, thus exposing humans and other mammals and birds to infection. Many questions remain unanswered about the host-parasite relationship, its epidemiology and public health significance. Veterinarians and clinicians are interested in its importance as a zoonosis. The parasite's capacity to cause ocular disease is of concern to ophthalmologists, while its propensity to stimulate allergic manifestations is of interest to allergologists, dermatologists and respiratory medicine specialists. Furthermore Toxocara provides a unique model system to explore questions in parasite biology.This book provides a comprehensive review of Toxocara and the disease it causes known as toxocariasis.Table of ContentsSection 1: Biology of Toxocara 1: Molecular biology and immunology of Toxocara canis 2: Molecular genetic characterization of members of the genus Toxocara - taxonomic, population genetic & epidemiological considerations 3: The larval surface, M Kennedy, University of Glasgow, UK 4: Toxocara and asthma 5: The significance of cerebral toxocariasis 6: Critical assessment of existing and novel model systems models for Toxocariasis 7: Diagnostic limitations and future trends in the serodiagnosis of human toxocariasis 8: Management and treatment options for human disease 9: Ocular toxocariasis 10: Toxocariasis and the skin 11: Inflammatory and immunological responses to Toxocaracanis 12: Novel approaches to immunoprophylaxis for toxocariasis 13: Epidemiological surveillance of Toxocara and Toxocariasis 14: Exposure and environmental contamination 15: Baylisascariasis: an emerging and potentially fatal form of larval migrans Section 3: Toxocara in the Veterinary context 16: Future options for the prevention and treatment of canids 17: Toxocariasis: the Veterinarian's role in prevention of zoonotic transmission 18: Toxocara vitulorum in Livestock Section 4: Economic impact of the disease 19: Economic impact of Toxocara spp.

Read more less

Book SynopsisGiardia and Cryptosporidium are both parasites of considerable global interest due to the gastrointestinal problems the organisms can cause in humans as well as domestic and wild animals. This book presents a comprehensive overview of recent research. Chapters discuss topics from taxonomy, nomenclature and evolution to molecular epidemiology, advances in diagnostics and zoonotic, human and animal health issues.Table of Contents1: Taxonomy, Nomenclature and Evolution 2: Molecular Epidemiology and Typing 3: Zoonotic, Human and Animal Health issues 4: Molecular epidemiology and typing 5: Clinical and Molecular Epidemiology 6: Advances in Diagnosis 7: Treatment of Drinking Water 8: Control in Water 9: Metabolomics and Transcriptome 10: Genomics 11: Prototeomics 12: Biochemistry and Physiology 13: Cell Biology and Signalling 14: Pathogenesis and Host-Parasite Relationship 15: Drug Treatment and Novel Drug Targets 16: Other Waterborne Protozoa 17: Basic Biology

Read more less

Book SynopsisThis volume is a republication in one volume of the 10 part CIH Keys to the Nematode Parasites of Vertebrates, first published between 1974 and 1983. For many years the ‘Keys’ have provided a working tool to those within the field and laboratory needing to know 'what is this worm?'. Now due to popular demand and to coincide with the long awaited publication of the supplement volume, the ‘Keys’ will be presented as one volume, refreshed and reformatted with the additional convenience of reordering in to superfamily. As an indispensable guide the ‘Keys’ shall continue to be an essential resource to those working within medical, veterinary and biological departments worldwide for many more years to come.Trade Review"'These keys are unique and absolutely essential to anybody engaged in diagnostic or research work involving nematodes' Prof. Ian Beveridge, The University of Melbourne, Australia"Table of Contents1: Glossary and Keys to Subclasses 2: Enoplida 3: Rhaditida 4: Strongylida 5: Strongylida 6: Strongylida 7: Strongylida 8: Oxyurida 9: Ascaridida 10: Ascaridida 11: Ascaridida 12: Spirurida 13: Spirurida 14: Spirurida

Read more less

Book SynopsisParasitic Nematodes are amongst the most successful parasites on Earth. This fully-updated second edition constitutes a comprehensive volume that continues to discuss the molecular biology, biochemistry and immunology of nematode parasites of humans, domestic animals and plants. There is a strong focus on new advances including chapters on horizontal gene transfer, genetics of susceptibility in humans, nematode protein structures, role of bacterial symbionts, host immune system modulation, modulation of allergic and autoimmune diseases by parasitic nematodes and the use of these organisms or their products as therapeutics. This book will be of significant importance to advanced students and researchers in human and veterinary parasitology, plant nematology and pathogen immunology in general.Table of ContentsPart 1: Evolution of parasitism and life history adaptations 1: The genome of Pristionchus and the evolution of parasitism 2: Life history placticity and responses to host defense 3: Horizontal gene transmission in plant parasites 4: Innate Immunity in Caenorhabditis elegans Part 2: Modulation of the host immune response 5: Nematodes and T regulatory cells 6: The alternatively activated macrophage 7: Modulation of autoimmune and allergic responses by defined nematode molecules 8: Tracking the host response in nematode immunity 9: Nematodes and regulation of the inflammatory response Part 3: Genetics of susceptibility and resistance 10: Susceptibility of humans to Ascaris 11: Genetics of resistance to hookworm 12: Population genetics and anthelmintic resistance to nematodes of domestic animals 13: Asthma, allergy and parasitic worm infections 14: Genetics of susceptibility - wild animals Part 4: Protection systems - Immune effectors, therapeutics, vaccines 15: Wolbachia as a therapeutic target 16: The Molecular Biology, Immunology and Chemotherapy of Wolbachia bacterial endosymbionts of filarial nematodes 17: Nematodes and human therapeutic trials 18: Vaccination against hookworms 19: Vaccination against filarial nematodes 20: Vaccination against nematodes of domestic animals 21: Immune regulation and multiple species infections 22: Effect of nematode infection on the immune response to other pathogens 23: Genetics of drug resistance in nematodes Part 5: Specialised and novel structures 24: Nervous system and neural communication molecules 25: Host cell and tissue modification 26: Cuticle synthesis and modification 27: Proteinases, from free-living to parasite 28: Nematode polyprotein structure"

Read more less

Book Synopsis

Read more less

Book SynopsisThis book covers current aspects of important infectious diseases affecting human and animal health in Latin American countries. Readers are equipped with details on arthropod vectors as well as on neglected health problems. Diseases covered include Neglected Tropical Diseases such as Chagas Disease, schistosomiasis, tungiasis, myiasis and leishmaniasis, but also Zika and Chikungunya viral infections, plague and yellow fever. One focus is given on parasitic transmission routes.In addition, the authors describe current therapeutic options and sustainable control measures, considering both human and animal health. By highlighting options within the interdisciplinary One Health approach, they round off this work into a cutting-edge reference for diverse expert readers. Scientists and clinicians concerned on public health, entomology, tropical medicine and parasitology not only in Latin America will find this collection particularly valuable.Finally, these contributions are essential in the framework of the Sustainable Development Goals and the targets of SDG 3 (Good Health and Well-being) in order to combat and end epidemics of Neglected Tropical Diseases. Table of ContentsFinal Table of Contents 1. Yellow fever2. Chikungunya3. Zika virosis: a known, but long time underestimated disease that got new and high attention before, during and after the Olympic Games in Brazil 20164. Plague5. Trypanosoma cruzi: an ancient and successful enzootic parasite6. The social and environmental determinants of the leishmaniases in the Americas7. Toxoplasmosis in South America8. Tunga spp. and Tungiasis in Latin America9. Human myiasis on the South American continent10. Schistosomiasis control: present situation and perspectives11. Hookworms in South America – a constant threat especially to children12. One Health Approach to Control Human and Zoonotic Hookworm Infections

Read more less