Description

Book Synopsis
Human African trypanosomiasis or sleeping sickness is caused by infection with the morphologically indistinguishable subspecies Trypanosoma brucei rhodesiense (in East and Southern Africa) and Trypanosoma brucei gambiense (in West and Central Africa). The disease is presently almost under control and less than 4000 cases are currently reported. In both, T. b. rhodesiense and T. b. gambiense infection, after the injection of infective metacyclic trypanosomes with tsetse fly vector saliva, the parasites establish in the skin, differentiate to the bloodstream stage and spread via the local draining lymph node into the vascular system. In this book, Chapter One presents an overview of the current epidemiology, clinical features, diagnosis and treatment options. Chapter Two provides an in-depth review of diagnostic methods for African trypanosomiasis. Chapter Three discusses the use of aminoadamantane derivatives against Trypanosoma brucei.

African Trypanosomiasis: Clinical Symptoms,

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A Paperback / softback by Gerald T Hughes

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    View other formats and editions of African Trypanosomiasis: Clinical Symptoms, by Gerald T Hughes

    Publisher: Nova Science Publishers Inc
    Publication Date: 01/04/2016
    ISBN13: 9781634847124, 978-1634847124
    ISBN10: 1634847121
    Also in:
    Medical parasitology

    Description

    Book Synopsis
    Human African trypanosomiasis or sleeping sickness is caused by infection with the morphologically indistinguishable subspecies Trypanosoma brucei rhodesiense (in East and Southern Africa) and Trypanosoma brucei gambiense (in West and Central Africa). The disease is presently almost under control and less than 4000 cases are currently reported. In both, T. b. rhodesiense and T. b. gambiense infection, after the injection of infective metacyclic trypanosomes with tsetse fly vector saliva, the parasites establish in the skin, differentiate to the bloodstream stage and spread via the local draining lymph node into the vascular system. In this book, Chapter One presents an overview of the current epidemiology, clinical features, diagnosis and treatment options. Chapter Two provides an in-depth review of diagnostic methods for African trypanosomiasis. Chapter Three discusses the use of aminoadamantane derivatives against Trypanosoma brucei.

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