Transplant surgery Books

Book SynopsisA beautifully written and compelling memoir of a largely unexplored area of medicine: transplant surgery.Leading transplant surgeon Dr Joshua Mezrich creates life from loss, moving organs from one body to another. In this intimate, profoundly moving work, he examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the stories of his own patients.Gripping and evocative, How Death Becomes Life takes us inside the operating room and presents the stark dilemmas that transplant surgeons must face daily: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? The human story behind the most exceptional medicine of our time, Mezrich's riveting book is a poignant reminder that a life lost can also offer the hope of a new beginning.Trade ReviewPart memoir and part historical account of the extraordinary pioneers who believed that people could berepaired and revived as the sum of their working parts... Moving * Financial Times *An outstanding memoir by a transplant surgeon who combines an autobiography and operating room dramatics with an equally engrossing history of his profession... this [medical memoir] ranks near the top [of the genre], in a class that includes arguably the best, Henry Marsh's Do No Harm * Kirkus Reviews *Monumental and enthralling. * New York Journal of Books *Fascinating... Compelling stories about an area of medicine shrouded in mystery. * Stephen Westaby *A beautifully written insight into an extraordinary area of medicine and a fascinating career. Heartbreaking and life-affirming in equal measure, it has all the makings of a classic. * Dr Max Pemberton, columnist and author of Trust Me, I'm a (Junior) Doctor *Table of Contents1: A Perfect Organ 2: Puzzle People 3: The Simple Beauty of the Kidney 4: Skin Harvest 5: Kidney Beans: Making Kidney Transplant a Reality 6: Open Heart: The Invention of Cardiopulmonary Bypass 7: Hearts on Fire: Making Heart Transplant a Reality 8: Sympathy for the Pancreas: Curing Diabetes 9: Prometheus Revisited: Liver Transplants and Thomas Starzl 10: Jason: The Secret Is to Live in the Present 11: Lisa and Herb: Should We Do Liver Transplants for Alcoholics? 12: Nate: The Selection Meeting, or Who Gets an Organ and Why? 13: Michaela: We Are All the Same on the Inside 14: As They Lay Dying 15: Healthy Donors: Do No Harm 16: Complications 17: Xenotransplantation: From One Species to Another 18: So, You Want to Be a Transplant Surgeon?

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Book Synopsis Manual de trasplante renal tiene el objetivo de mostrar todos los avances en el campo del trasplante renal de manera accesible, legible, práctica y bien ilustrada. Ideal para médicos, cirujanos, residentes y profesionales de enfermería que manejan pacientes con trasplante renal, abarca desde opciones de tratamiento para la enfermedad renal terminal hasta trasplante, manejo postoperatorio e inmunología de trasplantes, centrándose en cada aspecto clave de la práctica clínica.La 6.ª edición se ha actualizado y revisado para reflejar los conocimientos más actuales y la práctica en el campo. A lo largo de 23 capítulos, se muestran los tres pilares en los que se sustenta el complejo campo del trasplante de órganos: la investigación básica, que es la esencia del progreso y la innovación; la medicina del trasplante clínico, subespecialidad médica relativamente nueva; y los puntales éticos y culturales de toda la labor del trasplante, incluyendo el sentido de comunidad y solidaridad con respecto a la donación y la necesaria confianza absoluta entre personal médico, pacientes y familias. Características principales: Nuevos capítulos sobre asignación de órganos de donantes fallecidos y trasplante renal en países en desarrollo Ampliación de los capítulos sobre donación en vida y medicamentos inmunosupresores y protocolos Describe las principales preocupaciones relacionadas con el trasplante renal y los enfoques más exitosos con respecto a los problemas más habituales Abarca los aspectos inmunológicos que rodean a este importante tratamiento Apartado específico sobre el trasplante en países en vías de desarrollo y las implicaciones financieras y psicosociales del trasplante renal Secciones adicionales muy útiles como: trasplante renal pediátrico, aspectos psiquiátricos del trasplante, y aspectos legales y éticos que rodean al procedimiento Capítulo con la Declaración de Estambul sobre el tráfico de órganos y el turismo de trasplantes

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Book SynopsisIntracerebral interventions raise particular ethical issues. For instance, attempts at replacing lost or altered brain cells with the help of stem cells or the therapeutic application of Deep Brain Stimulation would have morally relevant implications. Many medically relevant questions and ethical concerns need to be clarified before these intracerebral interventions can become routine procedure: If the brain is conceived as the carrier of an individual's personality or of the self then operations on the brain can be seen as intrusions upon one's personality. The book addresses historical, philosophical, social and legal implications of these new developments in the neurosciences and aims at resolving some of the dilemmas that go hand in hand with "implanted minds".

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Book Synopsis Selected as a Doody's Core Title for 2022 and 2023! Concise, easy to read, and designed for quick reference, Quick Guide to Kidney Transplantation is a compact resource for general nephrologists, residents, fellows, nurse practitioners, and others involved in the care of post-transplant patients. Focusing on must-know clinical information needed to provide optimal patient care, this expertly written guide helps you gain the knowledge and expertise you need in this complex area. Offers high-yield, easy-to-reference information on areas of kidney transplantation relevant to the general nephrologist, including the management of immunosuppressive therapy, acute and long-term complications, transplant medications, drug interactions, selection and evaluation of potential living donors, and more. Features concise text presented in bullet-point format and highlighted by full-color illustrations. Shares the knowledge and exp

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Book SynopsisSaving lives through organ transplantation has become increasingly possible thanks to advances in research and care. Today, the complex field of transplantation continues to develop rapidly, fuelled by demographic change and further evolutions in scientific understanding. The Oxford Textbook of Transplant Anaesthesia and Critical Care has been written and edited by pioneers in the field of organ transplantation with an international team of authors, in order to equip anaesthetists and intensivists with the knowledge and training necessary to provide high quality and evidence-based care. The text addresses fundamentals aspects of scientific knowledge, care of the donor patient, transplant ethics and special considerations. Dedicated sections address each of the major organs; kidney, pancreas, liver, heart and lung, intestinal and multivisceral. Within each organ-based section, expert authors explore underlying disease, planning for transplantation, specialized procedures, perioperative Table of ContentsSECTION 1: INTRODUCTION; SECTION 2: INTRODUCTION TO TRANSPLANT ETHICS; SECTION 3: THE ORGAN DONOR; SECTION 4: THE SCIENTIFIC BASIS OF ORGAN TRANSPLANTATION; SECTION 5: KIDNEY AND KIDNEY - PANCREAS; SECTION 6: LIVER; SECTION 7: INTESTINAL AND MULTIVISCERAL; SECTION 8: HEART, LUNG, AND HEART-LUNG; SECTION 9: SPECIAL CONSIDERATIONS

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Book SynopsisAs the demand for blood and organs has grown, the value of a system that depends solely on gifts has been called into question. This title offers a fresh perspective on this ethical dilemma, by examining the social organization of blood and organ donation in Europe and the United States.Trade Review"In Last Best Gifts, Kieran Healy offers a timely, sophisticated, and original analysis of the complex organizational terrain of blood and organ donation. In doing so, he unpacks the crucial role that organizations and institutions play in creating the contexts for, and the meanings of, giving. His analysis suggests that the relationship between gifts and commodities, between giving and selling, is more complex than many scholars acknowledge." - Wendy Espeland, Northwestern University"

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Book SynopsisAs the demand for blood and organs has grown, the value of a system that depends solely on gifts has been called into question. This title offers a fresh perspective on this ethical dilemma, by examining the social organization of blood and organ donation in Europe and the United States.Trade Review"In Last Best Gifts, Kieran Healy offers a timely, sophisticated, and original analysis of the complex organizational terrain of blood and organ donation. In doing so, he unpacks the crucial role that organizations and institutions play in creating the contexts for, and the meanings of, giving. His analysis suggests that the relationship between gifts and commodities, between giving and selling, is more complex than many scholars acknowledge." - Wendy Espeland, Northwestern University"

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Book SynopsisAre our identities attached to our faces? If so, what happens when the face connected to the self is gone forever or replaced? In Face/On, Sharrona Pearl investigates the stakes for changing the face and the changing stakes for the face in both contemporary society and the sciences. The first comprehensive cultural study of face transplant surgery, Face/On reveals our true relationships to faces and facelessness, explains the significance we place on facial manipulation, and decodes how we understand loss, reconstruction, and transplantation of the face. To achieve this, Pearl draws on a vast array of sources: bioethical and medical reports, newspaper and television coverage, performances by pop culture icons, hospital records, personal interviews, films, and military files. She argues that we are on the cusp of a new ethics, in an opportune moment for reframing essentialist ideas about appearance in favor of a more expansive form of interpersonal interaction. Accessibly written and re

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Book SynopsisAre our identities attached to our faces? If so, what happens when the face connected to the self is gone forever or replaced? In Face/On, Sharrona Pearl investigates the stakes for changing the face and the changing stakes for the face in both contemporary society and the sciences. The first comprehensive cultural study of face transplant surgery, Face/On reveals our true relationships to faces and facelessness, explains the significance we place on facial manipulation, and decodes how we understand loss, reconstruction, and transplantation of the face. To achieve this, Pearl draws on a vast array of sources: bioethical and medical reports, newspaper and television coverage, performances by pop culture icons, hospital records, personal interviews, films, and military files. She argues that we are on the cusp of a new ethics, in an opportune moment for reframing essentialist ideas about appearance in favor of a more expansive form of interpersonal interaction. Accessibly written and re

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Book Synopsis''Compelling'' Christopher Hart, The Sunday Times''A fascinating book'' Daily Mail_______________________________________________________________We think of transplant surgery as one of the medical wonders of the modern world -- but it''s a lot older than you think. As ancient as the pyramids, its history is even more surprising. In Spare Parts, cultural historian Paul Craddock takes us on a fascinating journey and unearths incredible untold stories, from Indian surgeons regrafting lost noses in the sixth century BC, to the seventeenth century architect who helped pioneer blood transfusions, to the French seamstress whose needlework paved the way for kidney transplants in the early 1900s.Expertly weaving together philosophy, science and cultural history, Spare Parts explores how transplant surgery has constantly tested the boundaries between human, animal and machine. It shows us that the history -- and future -- of transplant surgery is tied up with questions not only about who we are, but also what we are, and what we might become._______________________________________________________________''By turns delightful and disturbing . . . A thoroughly engrossing read that I couldn''t put down'' LINDSEY FITZHARRIS, author of The Facemaker and The Butchering Art''Spare Parts is a fascinating read filled with adventure, delight and surprise'' RAHUL JANDIAL, surgeon and author of Life on a Knife''s Edge''This is a joyful romp through a fascinating slice of medical history'' WENDY MOORE, author of The Knife ManTrade ReviewA fascinating book * Daily Mail *Compelling -- Christopher Hart * The Sunday Times *The charm of Spare Parts comes from situating these landmarks in a wider history of ideas * Spectator *A thrilling and often terrifying ride through transplantation and the theories and techniques that made it possible . . . tantalizing -- Robert Sullivan * The New York Times *Anyone interested in the history of surgery will find much to amaze and startle in Paul Craddock's Spare Parts: A Surprising History of Transplants * Independent *Excellent . . . Much has been written about this subject, but with Spare Parts Paul Craddock has achieved something unique: a serious, entertaining and thoroughly researched work that usefully sets the history of transplantation in the context of the evolution of ideas about the human body -- Thomas Morris * TLS *Craddock combines meticulous scholarship with wry wit in lucid prose which is all the more powerful for being understated . . . Spare Parts is a triumph * Roger Kneebone, author of 'Expert' *I read Spare Parts with my mouth open, my eyes popping and my brain fizzing. It's a fascinating exploration of just how far humans will go to stay on the right side of death. I can't think of any other book whose pages will make you laugh, gasp, grimace and wince. Spare Parts is a triumph of medical story-telling * Michael Brooks, author of 'The Quantum Astrologer's Handbook' and 'Science(ish)' *This is a fascinating and sure-footed exploration of the medical, historical and mythological landscape in which humans use parts from each other to make themselves whole. With compassion and insight, Paul Craddock elucidates vital questions about what it means to be human and to realise our dreams of survival * Dr Emily Mayhew, author of 'Wounded' and 'The Four Horsemen' *This is a captivating and absorbing read that surprises on every page whether it be from prosthetic noses of the 16th Century to modern day bio-printing and stem cell technology * Professor Dame Sue Black, author of 'All That Remains' *Paul Craddock's book is a veritable tour de force, a tantalising journey through human efforts in understanding science, medicine, personal beliefs and ourselves over the past centuries . . .Packed with stories which bring to life the personalities, the heroes and villains, and, with benefit of hindsight, the sometime frankly incredulous ideas, we get a unique and inspiring tapestry of events . . . A thoroughly good read * Barry Fuller, Professor of Surgical Sciences at UCL Medical School *This compelling and impeccably researched history of transplant surgery puts you right at the heart of the gruesome action. An enthralling read * Richard Hollingham, author of 'Blood and Guts' *A riveting journey through the story of anatomical alchemy, Spare Parts is a fascinating read filled with adventure, delight and surprise * Rahul Jandial, surgeon and author of 'Life on a Knife’s Edge' *Spare Parts is such a pleasure to read, filled with so many fascinating characters and stories that seem almost too crazy to be real; I found myself chuckling, shaking my head and yet proud to be a part of this field. This is a must read for anyone that has ever been touched by transplantation or the gift of donation, a book that makes us proud of our macabre past and excited about what can only be a limitless future * Josh D Mezrich, author of 'How Death Becomes Life' *Stuffed with eccentric characters and questionable experiments, this is a joyful romp through a fascinating slice of medical history * Wendy Moore, author of 'The Knife Man' *A perfect blend of history, science and humanity on a thrilling journey around old and new parts of the human body * Matt Morgan, author of 'Critical' *Spare Parts uncovers the gripping birth of sharing body parts, and significantly, tells us all of our current 'good ideas and innovations' have been thought of and tested already - we are simply adding to the mix. This visceral book offers us an unparalleled historical treatise, as the world of complex transplantation continues to unravel and change * Daniel Saleh, award-winning consultant plastic and reconstructive surgeon *With curious and clinical precision ... Craddock raises questions about how we relate to one another, what stories we choose to privilege and who gets to tell them * Irish Times *By turns delightful and disturbing, even the most seasoned of medical history buffs will be astonished by Spare Parts. A thoroughly engrossing read that I couldn't put down. Hit that order button -- you won't regret it * Lindsey Fitzharris, author of The Butchering Art *An accessible and wide-ranging account . . . Amid the toe-curling descriptions of vivisected dogs and doomed trial runs at human-to-human tooth transplants are hopeful and inspiring accounts of how farmers and embroiderers shared their knowledge with medical practitioners . . . Thoroughly researched and appealingly digressive, this fascinating medical and cultural history sheds light on what it means to be human * Publishers Weekly *

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Book Synopsis1. The Early Surgeon-Anatomists.- 2. Physiology of the Exocrine Pancreas.- 3. The Endocrine Pancreas.- 4. Acute Pancreatitis.- 5. Chronic Pancreatitis, Including Pancreatic Lithiasis.- 6. Pancreatic Cysts, Pseudocysts, and Cystic Tumors.- 7. Trauma to the Pancreas.- 8. Congenital Anomalies.- 9. Tumors of the Ampulla of Vater and Pancreas (Non-Islet Cell).- 10. Treatment of Pancreatic and Ampullary Cancer.- 11. Progress in the Diagnosis of Pancreatic Diseases.- 12. Transplantation of the Pancreas and Islet Cells.- 13. The Lessons of History and Their Application to the Future.- Appendix: Notes on the Development of Pancreatology: Progress in Communications and Related Professional Societies.- Name Index.Trade ReviewFrom the reviews: "Although this book focuses on the history of the pancreas, it is a fascinating retreat into many other aspects of the history of medicine. John Howard and Walter Hess have spent their professional lives as academic pancreatic surgeons. Their book is the culmination of a prodigious effort to bring together a literature that begins with the Greek anatomist and surgeon Herophilus, who first described the pancreas around 300 b.c., and ends with the modern-day physicians and scientists who continue to expand our knowledge of the pancreas. History books can sometimes be a dull catalogue of events. Howard and Hess have made the journey personal with their insights into each investigator and into the ways in which various discoveries were made. Many of these discoveries were not focused efforts to understand the pancreas but observations made serendipitously. We are also treated to glimpses into the lives of many famous people, some of whom are well known for their discoveries outside the study of the pancreas but who also provided new knowledge of the anatomy and function of the pancreas. This well-organized book begins with early observations of the anatomy of the pancreas and accounts of the early experiments conducted to determine its function. We are brought from one of the first descriptions of the pancreas, as a "cushion of the stomach and pad supporting the vessels," to the discovery of the pancreatic duct by Johann Georg Wirsung in 1642. Wirsung made this discovery when he was a medical student in Padua, Italy, where he performed the autopsies before his mentor, Johann Wesling, presented the demonstration-lectures to the public in the anatomy theater. The next year, Wirsung was assassinated. His mentor, Wesling, was accused of the crime, the motive for which was rumored to be jealousy, but was eventually acquitted. Such vignettes add spice to the history of these discoveries and offer insight into the people who had a role in the history of knowledge about the pancreas and the times in which they lived. The studies that led to the determination of the function of the exocrine pancreas include those of Johann Conrad Brunner, who examined the effect of ligation of the pancreatic duct in dogs, the work of others who determined the acidity of pancreatic juice by tasting it, and Tiedemann and Gmelin's identification of the role of pancreatic juice and bile in digestion. Subsequent chapters focus on the history of acute and chronic pancreatitis, the discovery of the pancreatic islets and their relation to diabetes, and the identification of various tumors specific to this gland. The development of interventional approaches is presented in detail, including the first endoscopic retrograde cholangiopancreatography in 1965 by Rabinov and Simon, radiologists at Boston's Beth Israel Hospital, and the Whipple procedure in 1934 by Allen Whipple at the Columbia-Presbyterian Medical Center in New York. Many medical history books would stop at this point. This book, however, continues the journey into the present, bringing us up to date on contemporary researchers, new surgical procedures including islet-cell transplantation, and recently discovered genes. Although I initially found the size of this textbook daunting, the book is easy to read. This is in part owing to the fascinating portrayal of each of the major players who participated in developing our present understanding of the pancreas. It also reflects the authors' understanding of the history of medicine itself -- especially how discoveries were made before the era of high technology. This book will benefit not only anyone interested in the pancreas and the gastrointestinal tract, but also readers who want insights into the history of medicine." (Steven D. Freedman, M.D., Ph.D. in the New England Journal of Medicine, September 2003) "History Of The Pancreas creates a layered timeline meant to record the major discoveries surrounding the organ … . In sum, this treatise serves to outline the pancreas for clinicians and surgeons who now can use the information to formulate better approaches to patient treatment." (John Aiello, The Electric Review, January/February, 2009)Table of ContentsForeword. Preface. Acknowledgments. About the Authors. 1. The Early Surgeon-Anatomists. 2. Physiology of the Exocrine Pancreas. 3. The Endocrine Pancreas. 4. Acute Pancreatitis. 5. Chronic Pancreatitis, Including Pancreatic Lithiasis. 6. Pancreatic Cysts, Pseudocysts, and Cystic Tumors. 7. Trauma to the Pancreas. 8. Congenital Anomalies. 9. Tumors of the Ampulla of Vater and Pancreas (Non-Islet Cell). 10. Treatment of Pancreatic and Ampullary Cancer. 11. Progress in the Diagnosis of Pancreatic Diseases. 12. Transplantation of the Pancreas and Islet Cells. 13. The Lessons of History and Their Application to the Future. Appendix: Notes on the Development of Pancreatology: Progress in Communications and Related Professional Societies. Index of Persons. Index of Terminology.

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Book SynopsisEvery day, newspapers and television news programs present stories on the latest controversies over healthcare and medical advances, but they do not have the space to provide detailed background on the issues. This book provides an overview of the most controversial areas of healthcare.Trade Review"The first section of this book by Petechuk is titled Overview, but its four chapters, which cover history, organ procurement, organ allocation, and advances in transplantation, are all heavily imbued with ethical concerns. The six chapters of section 2, Controversies and Issues Relating to Transplantation, focus very specifically on the ethical issues of buying and selling organs, organ allocation, xenotransplantation, living donors, stem cell transplantation and research, and face transplants. An appendix of primary source documents provides a few brief government documents on various issues. The time line (in an appendix) reveals that the concept of organ transplantation existed as long ago as 400 BCE. A two-page glossary provides greater accessibility for readers without any health science knowledge. The bibliography is current, with entries as recent as 2005. A list of organizations and Web resources completes the text. This is a useful resource....Recommended. Lower-level undergraduates, two-year technical program students, and general readers." - Choice"Medical writer Petechuk explains all the sides of the issues for the informed general reader and beginning students, giving a brief history and describing organ procurement as an example of supply and demand, fair organ allocation, and future advanced anticipated, buying and selling organs, prioritizing potential recipients, animal use and infectious disease, living donors, stem cell transplantation, and the ethics behind face transplants. References given here include annotated primary source documents, a timeline, a glossary, and a list of further reading." - SciTech Book News

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Book SynopsisTable of ContentsEvolution of transplantation medicine BRIEF HISTORY OF PLT HEALTH SYSTEM BACKGROUND REQUIREMENTS FOR PLT Before transplantation Brain death criteria Non-heart beating donors Donor procurement Managing a scarce resource: Differences in donor allocation across the world INDICATIONS AND CONTRAINDICATIONS (and their evolution) - General aspects (List of diagnoses) PREPARATION FOR PLT Medical (immunisations/cardiac/renal/neurological aspects) Surgical and Radiological aspects Psychological/Social aspects Paediatric liver transplantation ANAESTHETIC ASPECTS (Risk assessment) SURGICAL ASPECTS (Choice of donor for PLT, Prevention of thrombosis/anticoagulation) SURGICAL TECHNIQUES Split graft Living-related Auxiliary Domino Techniques and present role of hepatocyte transplantation STRATEGIES IN IMMUNE SUPPRESSION (Immune ablation, renal-sparing, steroid-sparing) Management after Transplantation INTENSIVE CARE ASPECTS ANTI-INFECTION STRATEGIES Viral Bacterial Fungal EARLY COMPLICATIONS SURGICAL (biliary, vascular, etc.) MEDICAL ROLE OF HISTOLOGY AFTER PLT ROLE OF RADIOLOGY AND INTERVENTIONAL RADIOLOGY AFTER PLT LATE COMPLICATIONS SURGICAL (graft re-modelling, secondary portal hypertension/shunts) MEDICAL (recurrent disease post-PLT, de novo AIH, post-transplant lymphoproliferative disease, nephrotoxicity) PSYCHOSOCIAL ASPECTS AFTER PLT (social reintegration, medication adherence, family planning, education) PROSPECTS FOR IMMUNE TOLERANCE (possibilities for safe withdrawal of immunosuppression) TRANSITION TO ADULT SERVICES (smooth handover of care to a different system) FUTURE REQUIREMENTS

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Book SynopsisTrade ReviewDoody's Core Titles® 2022 "This is a one-of-a-kind book that presents very focused information in a simple, synthesized, and easy-to-digest format." -Natalie Neu, MD, MPH (Columbia University College of Physicians and Surgeons) Doody's Review Service

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Book SynopsisProvides transplant professionals with a step-wise approach to abdominal organ retrieval and bench surgery, illustrating complex anatomical situations and providing practice points and decision algorithms. A go-to reference for transplant surgeons, trainees and fellows, as well as for other professionals involved in abdominal organ transplantation.Table of ContentsList of Contributors vi Foreword viiPeter J. Morris Preface viii About the Companion Website ix 1 Organ Retrieval Logistics 1Murat Akyol and Victor L. Tswen Wen 2 Strategies in Preservation of Abdominal Organs 9Rutger J. Ploeg 3 Management of the Brainstem Dead Organ Donor 24Neil Young and Dermot McKeown 4 Multiorgan Retrieval 32Gabriel C. Oniscu 5 Kidney Retrieval and Bench Surgery 58John L. Forsythe 6 Liver Retrieval and Bench Surgery 73Gabriel C. Oniscu 7 Deceased Cardiac Donor Liver Retrieval 91Paolo Muiesan 8 In situ Liver Splitting 101Koji Hashimoto and John Fung 9 Ex situ Liver Splitting 116Dieter C. Bröering 10 Pancreas Retrieval and Bench Surgery 130Thomas Vogel and Peter J. Friend 11 Intestinal Retrieval and Bench Surgery 140Douglas G. Farmer Prawat Kositamongkol and Hasan Yersiz 12 Paediatric Age-Specific Aspects of Retrieval and Bench Surgery 155Chiara Grimaldi and Jean de Ville de Goyet Index 177

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Book SynopsisNeural transplantation can be used to treat neurodegenerative diseases through a variety of methods. The field is at a critical stage in its development, particularly in light of ongoing investigations into Parkinson's disease and alternatives to fetal transplantation.Trade Review"...well written with clear illustrations in many cases and extensively referenced..." (British Journal of Neurosurgery, Vol.16, No.6, 2002)Table of ContentsIntroduction (J. Gray). Cell Replacement Strategies for Neurodegenerative Disorders (A. Björklund). Functional Analysis of Fronto-Striatal Reconstruction by Striatal Grafts (S. Dunnett). Functional Reconstruction of the Hippocampus: Fetal Versus Conditionally Immortal Neuroepithelial Stem Cell Grafts (H. Hodges, et al.). Gene Transfer for Neuroprotection in Animal Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis (M. Bohn, et al.). Repair of Corticospinal Axons by Transplantation of Olfactory Ensheathing Cells (G. Raisman). Neural Transplantation in Parkinson's Disease (O. Lindvall). Transplantation of Human Fetal Striatal Tissue in Huntington's Disease: Rationale for Clinical Studies (T. Freeman, et al.). GENERAL DISCUSSION I: PROSPECTS FOR FETAL TRANSPLANTS. Neurotransplantation in Neurodegenerative Disease: A Survey of Relevant Issues in Developmental Neurobiology (J. Price, et al.). Molecular and Cellular Mechanisms in Immune Rejection of Intracerebral Neural Transplants (T. Brevig, et al.). Porcine Neural Xenografts: What are the Issues? (R. Barker). Gene Transfer Techniques for the Delivery of GDNF in Parkinson's Disease (J.-L. Ridet, et al.). Neurogenesis in the Adult Hippocampus (G. Kempermann & F. Gage). Neural Stem Cells are Uniquely Suited for Cell Replacement and Gene Therapy in the CNS (V. Ourednik, et al.). Functional Repair with Neural Stem Cells (J. Sinden, et al.). Remyelinating the Demyelinated CNS (W. Blakemore, et al.). GENERAL DISCUSSION II: THE ES CELL APPROACH. FINAL DISCUSSION: THE FUTURE FOR FETAL GRAFTS; STEM CELL STRATEGIES. Index of Contributors. Subject Index.

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Book Synopsis"Ethics of Organ Transplantation".Table of ContentsEDITORIAL BOARD. List of Contributors. Dedication. Preface. Organ donation and transplantation: a brief history of technological and ethical developments. Do we all have a responsibility to donate our organs?. Should we adopt a market strategy to organ donation?. Ethical issues in living related donors. Who should receive donor organs?. The ethics of organ retrieval. Ethical issues in non-heartbeating cadaver donors. The ethics of xenotransplantation. Public policy making in organ transplantation. An international perspective toward human organ donation and transplantation. The religious and spiritual perspective toward human organ donation and transplantation. The role and responsibility of the media in relation to organ donation and transplantation. Women, minorities and organ donation in transplantation. Organ transplantation issues in minors.

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Book SynopsisIn December, 1966, two patients dying of months after the transplants had been per­ uremia as a result of diabetic kidney disease formed.Table of Contents1. Experimental Pancreas Transplantation.- 2. Indications for Pancreas Transplantation.- 3. Pancreas Harvesting and Preservation Techniques.- 4. Anesthesia Management.- 5. Surgical Techniques.- 6. Cadaver Transplant Results.- 7. Living Related Pancreas Transplantation.- 8. Clinical Posttransplant Followup.- 9. Endocrine and Metabolic Response: Effect of Pancreas Transplantation on Diabetes Mellitus and Its Secondary Complications.- 10. Complications.- 11. Immunosuppression.- 12. Diagnosis and Management of Rejection.- 13. Pathology of Pancreatic Transplants.- 14. Duct-Occluded Pancreas Transplants.- 15. Bowel-Drained Pancreas Transplants.- 16. Urinary-Drained Pancreas Transplants.- 17. Future Prospects of Pancreas Transplantation.

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Book SynopsisLiver Transplantation, Part Three: Time for Surgery is a step-by-step guide to the experience of liver transplant surgery. It guides you right through the process, from receiving the call that your new liver is ready, through surgery, to recovery and discharge. With easy-to-understand language and vibrant illustrations, readers will learn what to expect during the surgery and how to prepare for the recovery process. This book is the third in a series on Liver Transplantation which, when used together, guides readers through the entire experience of having a liver transplant. Key facts and details about the surgery, including how long it takes and what happens during the procedure are included, to prepare and comfort you when it is time for your surgery. This informative and enjoyable book is part of the series The Strength of My Scars, written and illustrated by surgeon, Maria Baimas-George.

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Book SynopsisLung transplantation (LTx) is a life-saving treatment for people with very severe end-stage lung diseases. This concise, well-illustrated practical handbook provides a comprehensive overview of pre-, peri- and post-transplant care addressing the complexity of lung transplantation, general follow-up, and common post-transplant complications through simple, to-the-point, short topics that answer questions that trainees, fellows and consultants working in LTx departments have. It educates healthcare professionals involved in the care of LTx patients by explaining the general post-transplant journey, addressing typical post-transplant complications, and providing examples of real-life cases.Key Features:1. Provides answers to common clinical questions during the post-transplant journey of a lung transplant recipient. 2. Shares practical/pragmatic approach to diagnostic and management issues seen in the lung transplant population for clinicians from both within and e

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Book SynopsisA clinical guide to transplantation in lymphoma to present advanced knowledge on how to integrate, transplantat and other novel therapies in patients with lymphoid malignancies. It provides practical management guidance on how to integrate, transplant and other novel therapies in patients with lymphoid malignancies.Trade ReviewSir William Osler is reputed to have said, “Listen to the patient and he will give you the answer.” Had he been alive now and practicing transplantation for lymphoma, he could have well said “Read the Clinical Guide to Transplantation in Lymphoma and it will give you the answer.” These reviewers are very impressed by the breadth and scope of this book edited by Drs. Bipin Savani and Mohamed Mohty, ably aided by an array of expert contributors from all over the world.Clinical Guide to Transplantation in Lymphoma is extremely easy to read and very well written. In this era ofexponential information growth this book is surprisingly current, with the latest references. It has an ambitious scope, setting out to cover all aspects of transplantation in lymphoma and managing to meet that expectation.Chapters are laid out in logical sequence divided into 2 sections. Section 1 is particularly interesting and haschapters on the historical perspective of transplantation for lymphoma, transplant data collection and reporting, and analytical methods. The remainder of section 1 describes the general principles of transplantation in lymphomas, addressing issues such as mobilization, preparative regimens, and management of the early, late, and long-term issues arising after transplantation. Some chapters include transplantation for lymphoma in children, adults, and young adolescents; pretransplant evaluation; preparative regimens for autologous and allogeneic transplants; stem cell mobilization and stem cell source; post-transplant follow-up for autologousand allogeneic transplant, and a novel chapter, “First 100 Days of the Autologous Hematopoietic Stem Cell Transplantation Process in Lymphoma.” The chapters in section 1 are broadly applicable and would prove invaluable to trainees pursuing fellowships in hematopoietic cell transplantation.Section 2 is laid out as a chapter by chapter discussion of various lymphoma histologies and the applicability of hematopoietic cell transplantation in each. One can return to some of these chapters again and again because all common and most rare lymphoma subtypes (including HIV-associated lymphoma) are discussed in excellent detail. We found each one of these chapters to be remarkably up to date. In a field such ashematopoietic cell transplantation,where there is considerable ambiguity and few randomized studies, the authors and editors have maintained a neutral and unbiased tone,discussing the available data andguidelines exhaustively.Very few similar textbooks focus on transplantation in a disease group. Clinical Guide to Transplantation in Lymphoma is concise enough, practical, and clinically oriented to be considered a practical manual but at the same time manages to be comprehensive. Some unique features in this book are the numerous excellent graphs and tables and the discussion of case studies and clinical guidelines (United States and European) wherever applicable. We found very few typographic errors. For future editions we recommend at least 1 chapter devoted to the emerging field of cellular immunotherapy.The editors and the contributors need to be congratulated for an encyclopedic work that still manages to be a ready reference guide. This book will be used extensively and should be in the library of every transplanter.We hope it runs into many future editions and becomes the authoritative textbook for transplantation in lymphoma. (Yogesh Jethava, Parameswaran Hari, University of Arkansas for Medical Science, Biology of Blood and Marrow Transplantation, Nov 2015)Table of ContentsList of contributors vii Foreword xi Introduction 1 Section 1: Transplantation in lymphomas 1 Lymphoma and transplantation: historical perspective 5Andrew R. Rezvani 2 Lymphoma: working committee and data reporting after transplantation in lymphoma 13Wael Saber, Mehdi Hamadani, Shahrukh Hashmi and Parameswaran Hari 3 Use of transplantation in lymphoma: adults 23Parastoo Bahrami Dahi, Gabriela Soriano Hobbs and Miguel]Angel Perales 4 Hematopoietic stem cell transplantation for lymphoma in children, adolescents, and young adults 31Nader Kim El]Mallawany and Mitchell S. Cairo 5 Preparative regimens for lymphoma: autologous hematopoietic stem cell transplantation 45Taiga Nishihori, Karma Z. Salem, Ernesto Ayala and Mohamed A. Kharfan]Dabaja 6 Preparative regimens for lymphoma: allogeneic hematopoietic stem cell transplantation 57Mohamed A. Kharfan]Dabaja, Najla El]Jurdi, Mehdi Hamadani and Ernesto Ayala 7 Pretransplantation evaluation, comorbidities, and nondisease]related eligibility criteria for transplantation in lymphoma, 69Melissa Logue 8 Stem cell mobilization in lymphoma patients 75Tarah Ballinger, Bipin N. Savani and Mohamad Mohty 9 Allogeneic hematopoietic stem cell transplantation for lymphoma: stem cell source, donor, and HLA matching 85Michael Green and Mitchell Horwitz 10 Management of early and late toxicities of autologous hematopoietic stem cell transplantation 93Sai Ravi Pingali and Yago Nieto 11 Long]term follow]up of lymphoma patients after allogeneic hematopoietic cell transplantation 103Shylaja Mani and Navneet S. Majhail 12 First 100 days of the autologous hematopoietic stem cell transplantation process in lymphoma 109Angela Moreschi Woods 13 First 100 days of the allogeneic hematopoietic stem cell transplantation process in lymphoma 113Angela Moreschi Woods Section 2: Management 14 Stem cell transplantation in follicular lymphoma,119Satyajit Kosuri and Koen Van Besien 15 Chronic lymphocytic leukemia/small lymphocytic lymphoma 133Salyka Sengsayadeth and Wichai Chinratanalab 16 Diffuse large B]cell lymphoma 145Lauren Veltri, Bipin N. Savani, Mohamed A. Kharfan]Dabaja, Mehdi Hamadani and Abraham S. Kanate 17 Mantle cell lymphoma 161Sascha Dietrich and Peter Dreger 18 Hodgkin lymphoma 173Eva Domingo]Domenech and Anna Sureda 19 Peripheral T]cell lymphomas 187Giulia Perrone, Chiara De Philippis, Lucia Farina and Paolo Corradini 20 Transplantation in Burkitt and lymphoblastic lymphoma 201Gregory A. Hale 21 Transplantation in adult T]cell leukemia/lymphoma 209Ali Bazarbachi and Olivier Hermine 22 Hematopoietic cell transplantation for HIV]related lymphomas 217Joseph C. Alvarnas 23 Stem cell transplantation for mycosis fungoides/Sézary syndrome 233Eric D. Jacobsen 24 Role of transplantation in lymphoplasmacytic lymphoma 241Silvia Montoto and Charalampia Kyriakou 25 Transplantation outcome in primary mediastinal large B]cell lymphoma 247Amanda F. Cashen 26 Management of post]transplant lymphoproliferative disorders 253Jan Styczynski and Per Ljungman Appendix I Follow]up calendar after autologous stem cell transplantation in lymphoma 261Angela Moreschi Woods Appendix II Follow]up calendar after allogeneic stem cell transplantation in lymphoma 263Angela Moreschi Woods Index 265

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Book SynopsisProduced in association with the American Society of Transplantation, this new edition is full of practical advice for the next generation of transplant professionals. In addition to 5 organ-specific chapters: kidney, pancreas, heart, lung and liver, the book includes essential information on: immunobiology pharmacology donor management infectious complications pediatric transplantation general principles of patient management Fully updated and redesigned to make it even more user-friendly, the book now contains clinical vignettes, key point boxes, and self-assessment multiple choice questions in each chapter. Primer on Transplantation, Third Edition is an invaluable resource for all health professionals in the transplant team including trainees, residents, fellows, physicians, surgeons, nurses and transplant co-ordinators. Purchasing this book entitles you to access to the companTrade Review"This book strives to introduce a broad audience to the critical issues in solid organ transplantation. A book providing such an overview to people with a basic medical background is valuable to the educational mission of the American Society of Transplantation." (Doody's, 16 September 2011) Table of ContentsPreface vi Contributors vii Acknowledgments ix 1 Immunology of transplantation, 1Qiquan Sun, Jason M Zimmerer, and Gregg A Hadley 2 Pharmacology of transplantation, 18Ian AC Rowe and James M Neuberger 3 Medical management of the deceased donor in solid organ transplantation, 35John McCartney and Kenneth E Wood 4 Infectious diseases in transplantation, 51Robin K Avery and Jay A Fishman 5 Management of the successful solid organ transplant recipient, 73Elizabeth A Kendrick and Connie L Davis 6 Pediatric transplantation, 103William Harmon 7 Kidney and pancreas transplantation, 129Joshua J Augustine, Kenneth A Bodziak, Aparna Padiyar, James A Schulak, and Donald E Hricik 8 Heart transplantation, 171Maryl R Johnson, Walter G Kao, Elaine M Winkel, Joseph L Bobadilla, Takushi Kohmoto, and Niloo M Edwards 9 Lung transplantation, 205Jonathan E Spahr and Keith C Meyer 10 Liver transplantation, 238Kimberly A Brown, Mary Ann Huang, Marwan Kazimi, and Dilip Moonka Multiple choice questions, 274Answers to multiple choice questions, 291 Index 295

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Book Synopsis Selected as a 2023 Doody?s Core Title! With a strong focus on technical efficiency, Operative Techniques in Transplant Surgery takes you step by step through every aspect of solid organ transplantation surgery. Using concise text, full-color illustrations, and operative images, it provides detailed coverage of deceased and living donation, as well as liver, kidney, pancreas, and lung transplantation. You?ll find practical, step-by-step guidance on preoperative, intra-operative, and post-operative clinical decision making, helping you hone your skills and incorporate today?s innovative approaches into your surgical practice.Key Features More than 80 global contributors known for their technical expertise share their knowledge and skills. Each clinical issue is discussed in the same easy-to-follow format: definition, differential diagnosis, patient history and physical findings, imaging and other diagnostic studies, surgical management, techniques, pearls and pitfalls, postoperative care, outcomes, and complications. Comprehensive coverage keeps you up to date on every aspect of the field , including the management of complex portal hypertension in children and adults. Full-color, step-by-step explanations of operative procedures help you master each technique, avoid complications, and anticipate outcomes. Extensive tables and bulleted text allow for quick and easy reference, while intraoperative photographs provide a surgeons-eye view of each procedure. Ideal for anyone involved in transplantation, including medical students, residents, transplant physicians, surgical trainees, and practicing transplant surgeons. Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: Complete content with enhanced navigation . Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web. Cross-linked pages, references, and more for easy navigation. Highlighting tool for easier reference of key content throughout the text. Ability to take and share notes with friends and colleagues. Quick reference tabbing to save your favorite content for future use.

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Book SynopsisFocuses on every imaginable aspect of liver transplantation. This title offers you the protocols, surgical approaches, and techniques used in this challenging procedure.Trade Review2016 BMA Awards: Highly Commended, Surgical Specialties "Overall, the book should be an essential requirement in all liver transplantation units and be readily available to physicians and surgeons involved in liver transplantation at all stages in their training." --New England Journal of Medicine "This book is a rare gem - comprehensive, almost encyclopedic in scope, and highly authoritative with more than 200 medical doctors and other experts as contributors to its contents on a highly complex and detailed medical and surgical specialty - liver transplantation. It is essential to have, for anyone in this field." -Nano Khilnani, BizIndia.netTable of ContentsI: General Considerations 1. History of Liver Transplantation 2. Surgical Anatomy of the Liver 3. Molecular and Cellular Basics of Liver Failure 4. Influence of Transplantation on Liver Surgery 5. Organ Allocation: The US Model 6. Organ Allocation: The European Models 7. Donation After Cardiac or Brain Death: Regulatory and Ethical Principles II: Patient Evaluation: Adult 8. Current Indications, Contraindications, Delisting Criteria, and Timing for Transplantation 9. Transplantation for Hepatitis A and B 10. Natural History of Hepatitis C 11. Transplantation for Hepatitis C 12. Transplantation for Fulminant Hepatic Failure 13. Transplantation for Primary Biliary Cirrhosis 14. Transplantation for Sclerosing Cholangitis 15. Transplantation for Autoimmune Hepatitis 16. Transplantation for Primary Hepatic Malignancy 17. Transplantation for Cholangiocarcinoma 18. Transplantation for Metastases 19. Transplantation for Hematological Disorders 20. Transplantation for Budd-Chiari Syndrome 21. Transplantation for Alcoholic Liver Disease 22. Transplantation for Nonalcoholic Steatohepatitis 23. Unusual Indications for Transplantation III: Patient Evaluation: Pediatric 24. General Criteria for Transplantation in Children 25. Transplantation for Cholestatic Liver Disease in Children 26. Transplantation for Biliary Atresia in Children 27. Transplantation for Metabolic Disease in Children 28. Transplantation for Hepatic Malignancy in Children IV: Special Considerations in Patient Evaluation 29. Ethical Decisions in Transplantation 30. Psychiatric Assessment of Liver Transplant Candidates 31. Pretransplantation Evaluation: Cardiac 32. Pretransplantation Evaluation: Renal 33. Pretransplantation Evaluation: Infectious Disease 34. Role of the Clinical Nurse Coordinator 35. Radiological Evaluation in Transplantation 36. Monitoring and Care 37. Nutritional Aspects of Transplantation in Adults 38. Management of Portal Hypertensive Hemorrhage 39. Portopulmonary Hypertension and Hepatopulmonary Syndrome V: Operation 40. Donor Selection and Management 41. Extended Criteria Donors 42. Donating After Cardiac Death 43. The Donor Operation 44. Principles of Liver Preservation 45. Recipient Hepatectomy and Grafting 46. Anesthesia for Liver Transplantation VI: Split and Living Donor Transplantation 47. Imaging Techniques for Partial Grafting 48. Living Donor Transplantation in Children 49. Living Donor Transplantation: Evaluation and Selection in Adults 50. Adult Living Donor Right Hepatectomy and Recipient Operation 51. Adult Living Donor Left Hepatectomy and Recipient Operation 52. Split Liver Transplantation for Pediatric and Adult Recipients 53. Split Liver Transplantation for Two Adult Recipients 54. Biliary and Vascular Reconstruction in Living Donor Transplantation 55. Small-for-Size Syndrome 56. Minimally Invasive Living Donor Hepatectomy 57. Dual Grafts for Transplantation 58. Outcomes of Living Donor Transplantation: The Western Perspective 59. Outcomes of Living Donor Transplantation: The Eastern Perspective 60. Ethics of Living Donor Transplantation VII: Unusual Operative Problems 61. Arterial Reconstruction Pitfalls 62. Portal Vein Thrombosis and Other Venous Anomalies 63. Combined Liver-Kidney Transplantation 64. Retransplantation 65. Clinical Management of Necrotic Liver Before and After Transplantation 66. Intestinal and Multivisceral Transplantation 67. Transplantation: Situs Inversus and Polysplenia Syndrome 68. Auxiliary Transplantation VIII: Postoperative Care 69. Postoperative Intensive Care Management in Adults 70. Postoperative Intensive Care Management in Children 71. Postoperative Management Beyond the Intensive Care Unit: Adults 72. Postoperative Care of Pediatric Transplant Recipients 73. Transition of Pediatric Patients to Adulthood 74. Renal Failure in Adults 75. Graft Failure 76. Technical Problems: Biliary 77. Arterial Complications after Transplantation 78. Infections After Transplantation 79. Recurrent Hepatitis C After Transplantation 80. Late Complications and Recurrence of Disease After Transplantation 81. Neuropsychiatric Complications 82. Neurological Complications 83. Role of the Posttransplantation Clinical Nurse Coordinator IX: Transplant Pathology 84. Histopathology of Liver Transplantation 85. Pathology of NonNeoplastic Disease After Transplantation 86. Transplant-Related Malignancies X: Immunology of Liver Transplantation 87. Rejection After Transplantation 88. Leukocyte Chimerism- Meaning and Consequences 89. ABO, Tissue Typing, and Crossmatching Incompatibility 90. Graft-Versus-Host Disease XI: Immunosuppression 91. Induction and Maintenance of Immunosuppression 92. Special Considerations for Immunosuppression In Children 93. Treatment of Acute and Chronic Rejection 94. Novel Immunosuppression of Patients with Hepatic Malignancies 95. Novel Immunosuppressive Drugs 96. Immunosuppressive Biologic Agents 97. Long-term Toxicity of Immunosuppressive Therapy XII: Survival and Results 98. Outcome Predictors in Transplantation 99. U.S. Trends in Transplantation 100. Long-term Functional Recovery and Quality of Life 101. Survival and Quality of Life in Children XIII: Future Developments in Liver Transplantation 102. Genetic and Genomic Potentials in Liver Transplantation 103. Liver and Hepatocyte Xenotransplantation 104. Stem Cell and Liver Regeneration 105. Ischemia-Reperfusion Injury in Liver Transplantation 106. Extracorporeal Perfusion for Resuscitation of Marginal Grafts 107. Current Clinical Status of Extracorporeal Devices

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Book SynopsisLiver Anesthesiology and Critical Care Medicine emphasizes all aspects of this broad and important area and is the definitive textbook for anybody involved in the perioperative care of liver patients. The book is divided into three sections: Physiology and Pathophysiology, Anesthesiology, and Critical Care Medicine. The anesthesiology section contains information about liver transplantation and other liver surgeries and provides detailed practical direction and concise background information of all aspects of the anesthetic management of these patients based on the most recent evidence. The critical care section describes basic critical care management as it relates to liver surgical patients and addresses specific postoperative issues relevant for liver resection and liver transplant patients. The book combines practical guidance to the perioperative management with exTrade ReviewFrom the reviews:“The definitive resource for anesthesiologists and critical care physicians who provide perioperative care for the patient with liver disease.” (Ravindea Alok Gupta, Anesthesiology, Vol. 121 (1), July, 2014)“This is a comprehensive review of every aspect of liver transplant anesthesiology and associated critical care medicine. … The book is directed at anesthesiology and critical care attending physicians who provide care to liver patients. It should serve as the major reference on liver transplantation for fellows training in liver transplant anesthesia or in critical care. … It should also be available in every major medical library as a resource for anyone with an interest in any aspect of this field.” (Michael F. O’Connor, Doody's Book Reviews, April, 2013)Table of ContentsLiver Anesthesiology and Critical Care MedicineSection I: Physiology, Pathophysiology and Pharmacology of Liver Disease1. Physiology and Anatomy of the LiverTeresa A. MulaikalJean C. Emond2. Acute hepatic failureAndrew SlackNavjoyt LadherJulia Wendon3. Drug Metabolism in Liver FailureSimon Lam4. Evaluation of Liver Disease D. Robert DufourNazia QaziSection II: Anesthesiology for Liver Transplantation5. History of Liver TransplantationJ. R. Klinck6. Recipient and Donor Selection and Transplant Logistics – The European PerspectiveGabriela A. BerlakovichGerd R. Silberhumer7. Recipient and Donor Selection and Transplant Logistics - The US PerspectiveIngo KleinClaus U. Niemann8. Surgical Techniques in Liver TransplantationJuan del rio Martin9. Intraoperative MonitoringClaus-Georg Krenn10. Liver TransplantationAnna WaliaRoman Schumann11. Caval Cross-clamping, Piggyback & Veno-venous BypassRuairi MouldingPaul Picton12. Liver Transplantation: Hemodynamic Changes, Cardiac Output Monitoring and Inotropic SupportAnand D. PadmakumarMark C. Bellamy 13. Coagulopathy: Pathophysiology, Evaluation, and TreatmentMatthew R. KappusArun J. Sanyal14. Physiology, Prevention, and Treatment of Blood Loss During Liver TransplantationFreeha ArshadTon LismanRobert J. Porte15. The Marginal Liver Donor and Organ Preservation StrategiesConey BaeScot D. HenryGiridhar VedulaJames V. Guarrera16. Pediatric Liver TransplantationPhilipp J. Houck17. Combined Solid Organ Transplantation Involving the LiverGeraldine Diaz18. Liver Transplantation for the Patient with High MELDCynthia WangRandolph Steadman19. Perioperative Considerations for Transplantation in Acute Liver FailureChristopher P. SnowdenDavid M. Cressey20. Renal FailureLloyd MeeksJoseph Meltzer21. The Patient With Severe Co-Morbidities: Cardiac DiseaseShahriar ShayanAndre M. De Wolf22. Pulmonary Complications of Liver DiseaseMercedes Susan MandellMasahiko Taniguchi23. Liver Transplantation: The Patient with Severe Co-morbidities, CNS Disease, and Increased Intracranial PressureChris WillarsGeorg AuzingerSection III: Anesthesiology for Liver Surgery24. Hepatobiliary Surgery: Indications, Evaluation, and OutcomesMilan KinkhabwalaMarcelo Vivanco 25. Liver Resection Surgery: Anesthetic Management, Monitoring, Fluids and ElectrolytesJean MantzCatherine Paugam-Burtz26. Anesthetic Aspects of Living Donor HepatectomyNavraj KahlonTricia Brentjens27. Complications of Liver SurgeryOliver PanzerJennifer Sandadi28. The Patient with Liver Disease for Non-Hepatic SurgeryKatherine PalmieriRobert N. Sladen Section IV: Critical Care Medicine for Liver transplantation29. Routine Postoperative Care After Liver TransplantationJonathan HastieVivek K. Moitra30. ImmunosuppressionAmit GeraKosh Agarwal31. Acute Kidney Injury after Liver TransplantationRaymond M. PlaninsicTetsuro SakaiIbtesam A. Hilmi 32. Early Graft FailureJames TrotterSrinath Chinnakotla 33. Sepsis and InfectionFuat Hakan Saner34. Respiratory Failure and ARDSJames Y. FindlayMark T. Keegan 35. Pain Management in Liver TransplantationPaul WeykerChristopher WebbLeena Mathew Section V: Critical care Medicine for Liver surgery36. Post Operative Care Of Living Donor for Liver TransplantSubramanian SathishkumarTadahiro Uemura37. Liver Surgery – Early Complications: Liver Failure, Bile Leak and Sepsis Albert C.Y. ChanSheung Tat Fan

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Book SynopsisKidney transplantation is a medical procedure performed on patients with end-stage kidney disease that can increase their life expectancy by several years. However, the procedure involves some risk and potential complications. Chapter One of this monograph summarises the current strategy for diagnosis and treatment of chronic kidney disease-associated mineral bone disease (CKD-MBD) in kidney transplant recipients and aims to demonstrate the latest findings and therapeutic options in the field beyond recent published guidelines. Chapter Two describes the necessity of involving a psychiatrist in the transplant team to facilitate positive outcomes in kidney transplants, as psychological factors can contribute to treatment non-compliance and other issues. Chapter Three defines the surgical techniques used in living donor nephrectomy, discusses the use and reliability of these techniques in different patient groups, and examines the long-term follow-up results of donors and recipients. Lastly, Chapter Four discusses the variables involved in treating patients with autosomal dominant polycystic kidney disease (ADPCKD), whose enlarged and deformed kidneys can complicate kidney transplantation.Table of ContentsPreface; Calcium Phosphorus Metabolism and Mineral Bone Disease after Kidney Transplantation; Psychosocial Assessment of the Live Kidney Donor and Recipient; Donor Nephrectomy Techniques; Nephrectomy Timing for Polycystic Kidneys in Autosomal Dominant Polycystic Kidney Disease Patients Listed for Transplantation; Index.

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Book SynopsisA history of the little-known or forgotten academic origins of modern organ transplant surgery. This book investigates a crucial -- but forgotten -- episode in the history of medicine. In it, Thomas Schlich systematically documents and analyzes the earliest clinical and experimental organ transplant surgeries. In so doing helays open the historical origins of modern transplantation, offering a new and original analysis of its conceptual basis within a broader historical context. This first comprehensive account of the birth of modern transplantmedicine examines how doctors and scientists between 1880 and 1930 developed the technology and rationale for performing surgical organ replacement within the epistemological and social context of experimental university medicine. The clinical application of organ replacement, however, met with formidable obstacles even as the procedure became more widely recognized. Schlich highlights various attempts to overcome these obstacles, including immunologicalexplanations and new technologies of immune suppression, and documents the changes in surgical technique and research standards that led to the temporary abandonment of organ transplantation by the 1930s. Thomas Schlichis Professor and Canada Research Chair in the History of Medicine at McGill University.Trade ReviewSchlich highlights the fifty years preceding modern organ transplantation. This book. . . has historic interest referent to the biology discussed, demonstrating, for instance, that many ethical dilemmas are not the result of modern technology. . . This heavily annotated volume..should be a useful historical work for researchers generally. Recommended. * CHOICE *Table of ContentsAn ancient dream of mankind? What is special about organ transplantation? Before organ replacement: A natural history approach to disease The invention of organ transplantation Organotherapy and organ replacement Rise and decline of thyroid transplantation The discovery of a new organ: the parathyroid gland Laboratory and clinic: organ replacement for diabetes The many uses of the adrenal gland Reconstructing women: ovarian transplants Rejuvenating men: testicle transplants One principle, multiple applications: further organs From special case to prototype: the kidney Ethical problems with organ transplantation Laboratory and clinic: the epistemic and social context Methods of monitoring the success of transplants Disillusionment: The clinical failure of organ transplantation The strategy of technical perfection A new direction: transplant immunology Chance and necessity: a fresh start for organ transplantation

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Book SynopsisThe progress in HLA research achieved in the last decade has been extremely beneficial for understanding of the human genome structure, evolution of human beings and the association between HLA and complex related factors like immune responsiveness and patomechanism of some diseases. It was also found that some HLA specificities may bear a witness not only to a susceptibility to some diseases but also may reflect the ability of the host to mount immune responsiveness. All these achievements enabled successful clinical application of haematopoietic stem cells transplantation. Nowadays, it is apparent that the perfect matching at allele level of HLA specificities constitute the most important factor affecting surviving of patients transplanted from unrelated donors. This is also shown in this volume. To secure reliability of HLA typing , DNA techniques should be implemented and laboratories should comply with requirements expressed by European Federation for Immunogenetics (EFI) and American Society for Histocompatibility and Immunogenetics (ASHI). HLA typing is a complex procedure which should involve internal and external quality controls. Haematopoietic stem cell transplantation may be the best example of introducing modern technologies and very active translation of basic research in the fields of genetics and cell biology into the clinic. Even more impressive is international collaboration in searching for the best possible donor wherever in the world it might be. More than 8 million donors are registered world-wide. There is an ongoing interest in improving the international co-operation in order to secure the best donors for recipients. These chapters are of special interest as the co-operation for donors selection for HSCT is an activity across the oceans.

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Book SynopsisBlood and Marrow Transplantation (BMT) has evolved over the past 20 years into a successful therapy for a variety of malignant and non-malignant diseases. BMT allows for safer use of very high doses of radiotherapy and/or combination chemotherapy and can also allow for immunomodulation. The bone marrow -- the sponge-like tissue found in the centre of certain bones-contains stem cells that are the precursors of white blood cells, red blood cells, and platelets. These blood cells are vital for normal body functions, such as oxygen transport, defence against infection and disease, and clotting. Blood cells have a limited lifespan and are constantly being replaced; therefore, healthy stem cells are vital. In association with certain diseases, stem cells may produce too many, too few, or otherwise abnormal blood cells. Also, medical treatments may destroy stem cells or alter blood cell production. The resultant blood cell abnormalities can be life threatening. Bone marrow transplantation involves extracting bone marrow containing normal stem cells from a healthy donor, and transferring it to a recipient whose body cannot manufacture proper quantities of normal blood cells. The goal of the transplant is to rebuild the recipient''s blood cells and immune system and hopefully cure the underlying ailment. This book presents the latest research in this rapidly-growing field.

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Book SynopsisKidney transplantation has revolutionised the treatment of end-stage renal failure. Not only does it offer the best hope for complete rehabilitation, but it has also proved to be the most cost-effective of all treatment options, including dialysis. The surgical techniques involved have been mastered for half a century and are now considered routine. Nevertheless, this should not prevent us from appreciating the range and complexity of the issues surrounding kidney transplantation. This book examines the latest research in this field including rejection.

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Book SynopsisIn recent years, transplantation immunology has evolved as a distinct field founded on the recognition that rejection of a transplanted organ or tissue is mediated by immune mechanisms in the host responding to antigens in the donor tissue. Included within the scope are T cell immunity; Antigen presentation; Alloreactivity; Pancreas and islet cell transplantation; Allogeneic bone marrow transplantation Models of tolerance induction; Xenotransplantation and The swine leukocyte antigen (SLA) complex. This book gathers the latest research in the exciting new field of transplantation immunology.

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Book SynopsisThe issue of living organ donation is important because it represents one important set of possibilities for balancing the needs of people seeking organs with one another, and with the needs of potential organ donors. On one side of the balance, the drive to increase the supply of transplantable organs is fueled by people awaiting organ transplants. They are, in a sense, competing with one another on waiting lists for potentially life-saving scarce resources. On the other side of the balance, the drive to ensure that the transplant system is ethical and equitable precludes some mechanisms that would increase the supply of transplantable organs. Some options that have been rejected to date in the United States include paying healthy persons to donate their organs, and mandating that transplantable organs be harvested from all cadavers. To maintain the most ideal balance for the organ transplantation system, Congress may now wish to clarify whether certain new types of living organ donation should be adopted to increase the supply of transplantable organs, or prohibited for ethical and/or equitable reasons.

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Book SynopsisOrgan transplantation is one of the best therapeutic options for patients with end-stage organ failure. Experimental organ transplantation is an important link between basic science and clinical practice. Both editors, Dr Chen and Dr Qian, have been working in this area for over 20 years. Experts from the United States, Canada, China, Japan, Italy, Span, Turkey, Switzerland, Hungary, and Brazil contributed 25 chapters in this book, and provided detailed descriptions of techniques for vascularised organ allografts in mice, rats, pigs, and non-human primates, as well as detailed descriptions of non-vascularised pancreatic islet and spleen allografts. Furthermore, they discussed new advances in transplantation immunology. This book provides numerous important references which were carefully selected by the authors to extend their visions and knowledge. The appropriate readers of this book include medical students, graduate students, residents, surgeons, physicians and immunologists interested in the transplantation area.

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Book SynopsisIn Replacement Parts, internationally recognized bioethicist Arthur L. Caplan and coeditors James J. McCartney and Daniel P. Reid assemble seminal writings from medicine, philosophy, economics, and religion that address the ethical challenges raised by organ transplantation. Caplan's new lead essay explains the shortfalls of present policies. From there, book sections take an interdisciplinary approach to fundamental issues like the determination of death and the dead donor rule; the divisive case of using anencephalic infants as organ donors; the sale of cadaveric or live organs; possible strategies for increasing the number of available organs, including market solutions and the idea of presumed consent; and questions surrounding transplant tourism and "gaming the system" by using the media to gain access to organs. Timely and balanced, Replacement Parts is a first-of-its-kind collection aimed at surgeons, physicians, nurses, and other professionals involved in this essential lifesaving activity that is often fraught with ethical controversy.Trade ReviewThe variety of contributors keeps the subject material fresh. . . . The book is written in a way that is useful to both readers and those seeking a starting point for further research into the ethics related to organ donation and transplantation. . . . An excellent collaborative effort. * National Catholic Bioethics Quarterly *This is a high quality work with detailed arguments pertaining to increased organ donation. . . . Due to its comprehensive nature and argument compilation, this is a significant addition to the field. * Doody's Book Review *Table of ContentsIntroductionArthur L. Caplan Part One: The Dead Donor Rule, the Determination of Death, and Organ Transplantation from (Almost?) CadaversJames J. McCartney1. The Dead Donor Rule and the Concept of Death: Severing the Ties That Bind ThemElysa R. Koppelman2. The Theoretical and Practical Importance of the Dead Donor RuleJames J. McCartney3. The Dead-Donor Rule and the Future of Organ DonationRobert D. Truog, Frank G. Miller, Scott D. Halpern 4. The Dead Donor Rule: Effect on the Virtuous Practice of Medicine Frank C. Chaten 5. BRAIN DEATH without DefinitionsWinston Chiong 6. Accepting Brain Death David C. Magnus, Benjamin S. Wilfond, Arthur L. Caplan 7. Address to the International Congress on TransplantsKarol Wojtyla (Pope John Paul II) 8. Brain Death: Can It Be Resuscitated?D. Alan Shewmon 9. The Boundaries of Organ Donation after Circulatory DeathJames L. Bernat 10. Should We Allow Organ Donation Euthanasia? Alternatives for Maximizing the Number and Quality of Organs for TransplantationDominic Wilkinson and Julian Savulescu 11. The Ethics of Non-Heart-Beating Donation: How New Technology Can Change the Ethical LandscapeKristin Zeiler, Elisabeth Furberg, Gunnar Tufveson, Staffen Welin Part Two: The Use of Anencephalic Infants as Organ DonorsJames J. McCartney 12. Anencephalic Donors: Separate the Dead from the DyingAlexander Morgan Capron 13. Anencephalics as Organ DonorsRichard M. Zaner 14. Ethical Issues in the Use of Anencephalic Infants as a Source of Organs and Tissues for TransplantationArthur L. Caplan 15. Use of Anencephalic Newborns as Organ Donors: Position StatementCanadian Paediatric Society Part Three: Sale of Cadaveric or Live OrgansDaniel P. Reid16. Iranian Model of Paid and Regulated Living-Unrelated Kidney DonationAhad J. Ghods, and Shekoufeh Savaj 17. Regulated Payments for Living Kidney Donation: An Empirical Assessment of the Ethical ConcernsScott D. Halpern, Amelia Raz, Rachel Kohn, Michael Rey, David A. Asch, and Peter Reese 18. The Hidden Cost of Organ SaleSheila M. Rothman and David J. Rothman 19. Commercial Organ Transplantation in the PhilippinesLeigh Turner 20. Kidney Vending: The "Trojan Horse" of Organ TransplantationGabriel M. Danovitch, and Alan B. Leichtman 21. Financial Incentives for Cadaveric Organ DonationDavid Mayrhofer-Reinhartshuber and Robert Fitzgerald Part Four: Other Strategies for Increasing the Number of Available OrgansDanieil P. Reid22. Nudge, Nudge or Shove, Shove-The Right Way for Nudges to Increase the Supply of Donated Cadaver OrgansKyle Powys Whyte , Evan Selinger , Arthur L. Caplan, Jathan Sadowski 23. The Case for "Presumed Consent" in Organ DonationIan Kennedy, Robert A. Sells, Abdallah S. Daar, Ronald D. Guttmann, Raymond Hoffenberg, Michael Lock, Janet Radcliffe-Richards, and Nicholas Tilney24. A Critical Approach to the Current Understanding of Islamic Scholars on Using Cadaver Organs Without Prior PermissionSahin Aksoy 25. Priority in Organ Allocation to Previously Registered Donors: Public Perceptions of the Fairness and Effectiveness of Priority SystemsJennifer A. Chandler, Jacquelyn A. Burkell, and Sam D. Shemie 26. The Use of Prisoners as Sources of Organs-An Ethically Dubious PracticeArthur L. Caplan 27. Presumed Consent to Organ Donation in Three European Countries Barbara L Neades 28. Kidney Paired Donation 2011David Serur and Marion Charlton 29. Kidney Paired Donation C. Bradley Wallis, Kannan P. Samy, Alvin E. Roth, and Michael A. Rees 30. Some High Risk Kidneys Safe for TransplantKristina Fiore Part Five: Gaming the System Arthur L. Caplan31. The Declaration of Istanbul on Organ Trafficking and Transplant Tourism Participants in the International Summit on Transplant Tourism and Organ Trafficking Convened by the Transplantation Society and International Society of Nephrology in Istanbul, Turkey, April 30-May 2, 2008 32. The Hazards of Transplant TourismFrancis L. Delmonico 33. Transplant Tourism in China: A Tale of Two TransplantsRosamond Rhodes & Thomas Schiano 34. Multiple Listing in Kidney Transplantation Mohammad Sanaei Ardekani and Janis M. Orlowski5. Can Any System of Rationing Withstand the Plea of a Ten-Year-Old Girl? Arthur L. Caplan and Jennifer deSante ContributorsPermissions and CreditsIndex

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Book SynopsisClinical transplantation is still in the infancy stage with less than 60 years history. Despite recent successes, there are still several unresolved problems. This book tries to tackle some of these problems such as organ shortage, live donation, expanding the donor pool, ethical and legal issues regarding brain death concepts, the consent for donation process, and the use of human tissue for transplantation. The diversity of authors with different backgrounds such as physicians, philosophers, and ethicists, makes this book unique. The book tries to comprehensively discuss different issues from different angles that transplantation faces today. This book has 12 chapters discussing a wide variety of topics related to organ donors and donation.

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Book SynopsisThis book brings together researchers from three different continents who present different perspectives on the complex issue of organ donation. Several important authors have contributed to this edited book on organ donation discussing the phenomenon from different aspects, particularly the psychological, medico-legal, religious and communications perspectives. Some of the authors have not only studied these questions academically, but they themselves are live organ donors or organ recipients as well. The chapters by Cole, Camilleri-Zahra, Schweda and Wolhke, Siegel, Anker and Jansen give importance to the voice of organ donors, recipients and their families. They discuss the dilemmas which donors, recipients and their families face when they come to learn that a family member needs an organ transplant, and the subsequent difficult decisions that have to be made by the recipients, possible donors and family members. The phases before and after the donation of organs are as important as the donation itself. Fear, guilt and other strong emotions are intrinsic to the donation process both in live donation as well as in cadaveric donation. The psychological and health challenges presented by organ donation, discussed by Lauri, Maloney, Walker and Charlton, Shanteau and Hyde, are compounded by legal, religious and cultural issues, which will also be discussed in different chapters of the book by Ellul, Borg and Reinhart. Finally, the chapters by Alvaro, Feeley and Yang discuss how the media can influence and inform public attitudes towards organ donation and discuss how it can help increase the number of organ donors. This book is meant for those who, in some way, come in contact with people who need an organ transplant and those who have to help people come to reach informed decisions.

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Book SynopsisThis book depicts the basic aspects of all surgeries for kidney transplantation in both adults and children, including procurement of kidney, preparation of the kidney graft, vessel reconstruction, kidney implantation in various conditions and the diagnosis and management of surgical complications post-transplant. This book also describes the surgery for kidney transplant with abnormal lower urinary tract; the surgery for third or subsequent kidney transplant and the surgery for transplant nephrectomy by the extra capsule or intra capsule technique. Furthermore, it has been emphasized that early recognition of vascular complications is critical in order to avoid the kidney graft loss. This book provides numerous images to illustrate the abnormal findings during the investigation of kidney graft, in order to facilitate prompt diagnosis and management of post-transplant complications. Moreover, the different techniques in management of urological complications are discussed such as Boari flap urinary tract reconstruction. This book also introduces advanced laparoscopic surgery for kidney implantation. The authors share their experiences in developing the large animal training model and early clinical experience. Importantly, editors invited Professor Modi to contribute to the chapters on laparoscopic kidney transplant and robotic kidney transplant. Professor Modi is a well-known pioneer in advanced laparoscopic kidney transplant and robotic kidney transplant. Last but not least, the assessment of live kidney donor has been thoroughly discussed based on the review of the guidelines from a few societies. The surgery for donor nephrectomy by either transperitoneal or retroperitoneal approach has been well illustrated in details with pictures. This book is written based on the authors'' 20 years'' experience in kidney transplantation. It is hoped to be helpful for transplant fellows and junior transplant surgeons.

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