Description

Book Synopsis
Organized by substance and featuring the latest research on industrial toxicants, this book provides academics and professionals with an accessible reference and resource. The book offers comprehensive coverage, employing a succinct chapter format that has become Hamilton & Hardy s hallmark.

Trade Review

'Hamilton and Hardy�s Industrial Toxicology is now 80 years old, and the new sixth edition links us with a pioneer era.' (British Occupational Hygiene Society 2016)

'...a useful reference text for occupational practitioners seeking a one-stop overview of the occupational toxicology of specific substances...' (Occupational Medicine,7th September 2016https://academic.oup.com/occmed/article-abstract/66/7/588/2222779/Hamilton-and-Hardy-s-Industrial-Toxicology?redirectedFrom=fulltext)



Table of Contents

Contributors xiii

Abbreviations xvii

The Heritage of Alice Hamilton MD and Harriet Hardy MD xix

In Memory xxi

Preface xxiii

Section I Introduction 1
Section Editor: Raymond D. Harbison

1 The Modern Approach to the Diagnosis of Occupational Disease 3
Raymond D. Harbison and Jeffrey H. Mandel

2 Controls of Occupational Diseases 13
Daniel A. Newfang, Giffe T. Johnson, and Raymond D. Harbison

Section II Metals and Metalloids 19
Section Editor: Richard V. Lee

3 Introduction 21
Richard V. Lee

4 Alkali Compounds 25
Steve Morris and Ann Lurati

5 Aluminum 33
Giffe T. Johnson

6 Antimony 39
Marie M. Bourgeois

7 Arsenic 45
Janice S. Lee and Santhini Ramasamy

8 Barium 57
Marie M. Bourgeois

9 Beryllium 63
Alison J. Abritis and Raymond D. Harbison

10 Bismuth and Related Compounds 73
Paul Jonmaire

11 Boron 79
Giffe T. Johnson

12 Cadmium 85
Frank D. Stephen

13 Chromium 95
Kathleen Macmahon

14 Cobalt 101
Davinderjit Singh and Raymond D. Harbison

15 Copper 109
Marie M. Bourgeois

16 Gallium and Indium 115
Jayme P. Coyle and Raymond D. Harbison

17 Germanium 119
Marek Banasik

18 Gold 123
Marek Banasik

19 Iron 127
Steve Morris and Jayme P. Coyle

20 Lead 131
Frank D. Stephen

21 Lithium 141
Ushang Desai

22 Manganese 149
Alex Lebeau

23 Mercury 157
Frank D. Stephen

24 Molybdenum 167
Paul Jonmaire

25 Nickel 173
Robyn L. Prueitt and Julie E. Goodman

26 Tantalum and Niobium 183
Jayme P. Coyle and Raymond D. Harbison

27 Platinum Group Elements: Palladium, Iridium, Osmium, Rhodium, and Ruthenium 187
Alex Lebeau

28 Platinum 193
Alex Lebeau

29 Rare Earth Metals 199
Raymond D. Harbison and David R. Johnson

30 Selenium and its Compounds 205
Anna M. Fan and Marco Vinceti

31 Silver 229
Giffe T. Johnson

32 Tellurium 233
Marek Banasik

33 Thallium 239
Nikolay M. Filipov

34 Tin 247
Raymond D. Harbison and David R. Johnson

35 Titanium 253
Ushang Desai and Raymond D. Harbison

36 Tungsten 257
Kambria K. Haire and Raymond D. Harbison

37 Vanadium 261
James C. Ball and Maureen R. Gwinn

38 Zinc 277
Giffe T. Johnson

39 Hafnium and Zirconium 283
Kambria K. Haire, Jayme P. Coyle, and Raymond D. Harbison

40 Metal Fume Fever and Metal-Related Lung Disease 289
Thomas Truncale

Section III Chemical Compounds I 301
Section Editor: Raymond D. Harbison

41 Introduction 303
Raymond D. Harbison

42 Carbon Dioxide 305
Debra J. Price

43 Carbon Monoxide 309
Erin L. Pulster and James V. Hillman

44 Carbon Disulfide 317
Debra J. Price

45 Hydrogen Sulfide 325
Stephen C. Harbison and Jacob R. Bourgeois

46 Cyanide 331
Erin L. Pulster and James V. Hillman

47 Halogens 341
Joseph A. Puccio

48 Phosgene 357
Benjamin Wong, Michael W. Perkins, and Alfred M. Sciuto

49 Nitrogen Compounds 363
Kathleen T. Jenkins

50 Oxygen and Ozone 371
Robert A. Klocke

51 Phosphorus Compounds 383
M. Rony Francois and Frank Stephen

52 Sulfur Compounds 391
Frank Stephen and M. Rony Francois

Section IV Organic Compounds 401
Section Editor: Raymond D. Harbison

53 Aliphatic Hydrocarbons 403
Mayowa Amosu, Nicole Nation, and Mary Alice Smith

54 Alcohols and Glycols 419
Kelly W. Hall

55 Aldehydes and Ketones 445
Jason S. Garcia and Raymond D. Harbison

56 Ethers and Epoxides 491
Erin L. Pulster, Jacob R. Bourgeois, and Raymond D. Harbison

57 Esters 505
Raymond D. Harbison and C. Clifford Conaway

58 Chlorinated Hydrocarbons 541
Michael H. Lumpkin

59 Other Halogenated Hydrocarbons 567
Michael H. Lumpkin

60 Aromatic Hydrocarbons 581
Raymond D. Harbison, Amora Mayo-Perez, David R. Johnson, and Marie M. Bourgeois

61 Amino and Nitro Compounds 615
David Y. Lai and Yin-Tak Woo

62 Methyl Tert-Butyl Ether (MTBE) 643
Janice S. Lee and Robyn Blain

63 Ethyl Tertiary Butyl Ether (ETBE) 651
Keith D. Salazar

64 tert-Butyl Alcohol 657
Janice S. Lee

65 Naphthalene 663
Lisa A. Bailey, Laura E. Kerper, and Lorenz R. Rhomberg

66 Gasoline (Petrol, Motor Spirits, Motor Fuel, Natural Gasoline, Benzin, Mogas) 669
Raymond D. Harbison and Daniel A. Newfang

67 1-Bromopropane 677
Marek Banasik

68 Diacetyl 683
David J. Hewitt

69 Perfluoroalkyl Compounds 689
Jason S. Garcia and Raymond D. Harbison

70 Tetrahydrofuran 719
Ghazi A. Dannan

71 Perchloroethylene (Tetrachloroethylene) 727
David G. Dodge and Julie E. Goodman

72 Trichloroethylene 733
David G. Dodge and Julie E. Goodman

73 Acrylonitrile 741
Jason M. Fritz and April M. Luke

Section V Organic High Polymers, Monomers, and Polymer Additives 755
Section Editor: Raymond D. Harbison

74 Introduction 757
Raymond D. Harbison

75 Plastics 759
Marek Banasik

76 Elastomers 785
Marek Banasik

77 Synthetic Fibers 791
Marek Banasik

78 Bisphenol A (4,4´-Isopropylidenediphenol) 795
Julie E. Goodman, Lorenz R. Rhomberg, and Michael K. Peterson

79 Polystyrene/Styrene 809
Leslie A. Beyer and Julie E. Goodman

80 Phthalates 815
Robert W. Benson

81 Decabromodiphenyl Ethane 821
Marek Banasik

82 Tetrabromobisphenol A 827
David Y. Lai

83 Tris[2-Chloro-1-(Chloromethyl)Ethyl] Phosphate (TDCPP) 837
Marek Banasik

84 Tris(2-Chloro-1-Methylethyl) Phosphate (TCPP) 845
Marek Banasik

Section VI Pesticides 855
Section Editor: Raymond D. Harbison

85 Introduction 857
Raymond D. Harbison

86 Insecticides 859
Carol S. Wood

87 Herbicides 877
Giffe T. Johnson

88 Fungicides 901
Amora Mayo-Perez and Raymond D. Harbison

89 Rodenticides 917
Daniel L. Sudakin

Section VII Dusts and Fibers 927
Section Editor: Raymond D. Harbison

90 Introduction 929
David R. Johnson

91 Benign Dusts (Nuisance Dusts) 931
Humairat H. Rahman and Raymond D. Harbison

92 Fibrogenic Dusts 935
Charles Barton

93 Mixed Dusts 949
Charles Barton

94 Synthetic Vitreous Fibers 959
Thomas Truncale and Yehia Y. Hammad

95 Organic Dusts 969
David R. Johnson

96 Naturally Occurring Mineral Fibers 997
Ali K. Hamade, Christopher M. Long, and Peter A. Valberg

97 Nanoparticles 1025
Daniel A. Newfang, Giffe T. Johnson, and Raymond D. Harbison

Section VIII Physical Agents 1029
Section Editor: Marie Bourgeois

98 Radio-Frequency Radiation 1031
R. Timothy Hitchcock

99 Optical Radiation: Ultraviolet, Visible Light, Infrared, and Lasers 1045
Joseph M. Greco

100 Ionizing Radiation 1055
Thomas A. Lewandowski, Juhi K. Chandalia, and Peter A. Valberg

101 Electromagnetic Waves (EMF and RF) and Health Effects 1069
Peter A. Valberg

102 Traumatogens Associated with Carpal Tunnel Syndrome 1087
Joan M. Watkins

103 Vibration 1099
Donald E. Wasserman

104 Occupational Noise 1115
David L. Dahlstrom

105 Heat Stress Illness 1123
Marie M. Bourgeois and David R. Johnson

Section IX Special Topics 1129
Section Editor: Raymond D. Harbison

106 Mode of Action/Human Relevance Framework 1131
M.E. (Bette) Meek

107 Carcinogenesis 1135
Carlos A. Muro-Cacho

108 Genotoxicity Testing Strategies, Guidelines, and Methods 1173
Ching-hung Hsu and Qingli Wang

109 Human Relevance of Rodent Leydig Cell Tumors 1189
Thomas J. Steinbach, Robert. R. Maronpot, and Jerry F. Hardisty

110 Reproductive Toxicology 1197
Judith W. Henck

111 Developmental Toxicology 1229
Thomas A. Lewandowski

112 Ototoxicity 1241
Matthew Mifsud and K. Paul Boyev

113 Dermal and Ocular Toxicity 1247
Jayme P. Coyle, Alison J. Abritis, Amora Mayo-Perez, Marie M. Bourgeois, and Raymond D. Harbison

114 Reactive Airways Dysfunction Syndrome (RADS) 1259
David J. Hewitt

115 Pulmonary Sensitization 1263
David J. Hewitt

116 “Street” and Prescription Drug Abuse 1267
Sharon S. Kelley, James Godin, and John Christie

117 Mycotoxins 1283
Clara Y. Chan and Bruce J. Kelman

118 Phosphine 1295
Michael W. Perkins, Benjamin Wong, Dorian Olivera, and Alfred Sciuto

119 Diesel Exhaust 1301
J. Michael Berg, Phillip T. Goad, and Thomas W. Hesterberg

120 Spaceflight Operations 1311
Michael A. Cardinale, Philip J. Scarpa, James R. Taffer, and Daniel Woodard

121 Regulatory Toxicology 1321
David M. Polanic and Marek Banasik

Index 1331

Hamilton Hardys Industrial Toxicology 6e

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A Hardback by R Harbison, Marie M. Bourgeois, Giffe T. Johnson

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    View other formats and editions of Hamilton Hardys Industrial Toxicology 6e by R Harbison

    Publisher: Wiley-Blackwell
    Publication Date: 5/26/2015 12:00:00 AM
    ISBN13: 9780470929735, 978-0470929735
    ISBN10: 0470929731

    Description

    Book Synopsis
    Organized by substance and featuring the latest research on industrial toxicants, this book provides academics and professionals with an accessible reference and resource. The book offers comprehensive coverage, employing a succinct chapter format that has become Hamilton & Hardy s hallmark.

    Trade Review

    'Hamilton and Hardy�s Industrial Toxicology is now 80 years old, and the new sixth edition links us with a pioneer era.' (British Occupational Hygiene Society 2016)

    '...a useful reference text for occupational practitioners seeking a one-stop overview of the occupational toxicology of specific substances...' (Occupational Medicine,7th September 2016https://academic.oup.com/occmed/article-abstract/66/7/588/2222779/Hamilton-and-Hardy-s-Industrial-Toxicology?redirectedFrom=fulltext)



    Table of Contents

    Contributors xiii

    Abbreviations xvii

    The Heritage of Alice Hamilton MD and Harriet Hardy MD xix

    In Memory xxi

    Preface xxiii

    Section I Introduction 1
    Section Editor: Raymond D. Harbison

    1 The Modern Approach to the Diagnosis of Occupational Disease 3
    Raymond D. Harbison and Jeffrey H. Mandel

    2 Controls of Occupational Diseases 13
    Daniel A. Newfang, Giffe T. Johnson, and Raymond D. Harbison

    Section II Metals and Metalloids 19
    Section Editor: Richard V. Lee

    3 Introduction 21
    Richard V. Lee

    4 Alkali Compounds 25
    Steve Morris and Ann Lurati

    5 Aluminum 33
    Giffe T. Johnson

    6 Antimony 39
    Marie M. Bourgeois

    7 Arsenic 45
    Janice S. Lee and Santhini Ramasamy

    8 Barium 57
    Marie M. Bourgeois

    9 Beryllium 63
    Alison J. Abritis and Raymond D. Harbison

    10 Bismuth and Related Compounds 73
    Paul Jonmaire

    11 Boron 79
    Giffe T. Johnson

    12 Cadmium 85
    Frank D. Stephen

    13 Chromium 95
    Kathleen Macmahon

    14 Cobalt 101
    Davinderjit Singh and Raymond D. Harbison

    15 Copper 109
    Marie M. Bourgeois

    16 Gallium and Indium 115
    Jayme P. Coyle and Raymond D. Harbison

    17 Germanium 119
    Marek Banasik

    18 Gold 123
    Marek Banasik

    19 Iron 127
    Steve Morris and Jayme P. Coyle

    20 Lead 131
    Frank D. Stephen

    21 Lithium 141
    Ushang Desai

    22 Manganese 149
    Alex Lebeau

    23 Mercury 157
    Frank D. Stephen

    24 Molybdenum 167
    Paul Jonmaire

    25 Nickel 173
    Robyn L. Prueitt and Julie E. Goodman

    26 Tantalum and Niobium 183
    Jayme P. Coyle and Raymond D. Harbison

    27 Platinum Group Elements: Palladium, Iridium, Osmium, Rhodium, and Ruthenium 187
    Alex Lebeau

    28 Platinum 193
    Alex Lebeau

    29 Rare Earth Metals 199
    Raymond D. Harbison and David R. Johnson

    30 Selenium and its Compounds 205
    Anna M. Fan and Marco Vinceti

    31 Silver 229
    Giffe T. Johnson

    32 Tellurium 233
    Marek Banasik

    33 Thallium 239
    Nikolay M. Filipov

    34 Tin 247
    Raymond D. Harbison and David R. Johnson

    35 Titanium 253
    Ushang Desai and Raymond D. Harbison

    36 Tungsten 257
    Kambria K. Haire and Raymond D. Harbison

    37 Vanadium 261
    James C. Ball and Maureen R. Gwinn

    38 Zinc 277
    Giffe T. Johnson

    39 Hafnium and Zirconium 283
    Kambria K. Haire, Jayme P. Coyle, and Raymond D. Harbison

    40 Metal Fume Fever and Metal-Related Lung Disease 289
    Thomas Truncale

    Section III Chemical Compounds I 301
    Section Editor: Raymond D. Harbison

    41 Introduction 303
    Raymond D. Harbison

    42 Carbon Dioxide 305
    Debra J. Price

    43 Carbon Monoxide 309
    Erin L. Pulster and James V. Hillman

    44 Carbon Disulfide 317
    Debra J. Price

    45 Hydrogen Sulfide 325
    Stephen C. Harbison and Jacob R. Bourgeois

    46 Cyanide 331
    Erin L. Pulster and James V. Hillman

    47 Halogens 341
    Joseph A. Puccio

    48 Phosgene 357
    Benjamin Wong, Michael W. Perkins, and Alfred M. Sciuto

    49 Nitrogen Compounds 363
    Kathleen T. Jenkins

    50 Oxygen and Ozone 371
    Robert A. Klocke

    51 Phosphorus Compounds 383
    M. Rony Francois and Frank Stephen

    52 Sulfur Compounds 391
    Frank Stephen and M. Rony Francois

    Section IV Organic Compounds 401
    Section Editor: Raymond D. Harbison

    53 Aliphatic Hydrocarbons 403
    Mayowa Amosu, Nicole Nation, and Mary Alice Smith

    54 Alcohols and Glycols 419
    Kelly W. Hall

    55 Aldehydes and Ketones 445
    Jason S. Garcia and Raymond D. Harbison

    56 Ethers and Epoxides 491
    Erin L. Pulster, Jacob R. Bourgeois, and Raymond D. Harbison

    57 Esters 505
    Raymond D. Harbison and C. Clifford Conaway

    58 Chlorinated Hydrocarbons 541
    Michael H. Lumpkin

    59 Other Halogenated Hydrocarbons 567
    Michael H. Lumpkin

    60 Aromatic Hydrocarbons 581
    Raymond D. Harbison, Amora Mayo-Perez, David R. Johnson, and Marie M. Bourgeois

    61 Amino and Nitro Compounds 615
    David Y. Lai and Yin-Tak Woo

    62 Methyl Tert-Butyl Ether (MTBE) 643
    Janice S. Lee and Robyn Blain

    63 Ethyl Tertiary Butyl Ether (ETBE) 651
    Keith D. Salazar

    64 tert-Butyl Alcohol 657
    Janice S. Lee

    65 Naphthalene 663
    Lisa A. Bailey, Laura E. Kerper, and Lorenz R. Rhomberg

    66 Gasoline (Petrol, Motor Spirits, Motor Fuel, Natural Gasoline, Benzin, Mogas) 669
    Raymond D. Harbison and Daniel A. Newfang

    67 1-Bromopropane 677
    Marek Banasik

    68 Diacetyl 683
    David J. Hewitt

    69 Perfluoroalkyl Compounds 689
    Jason S. Garcia and Raymond D. Harbison

    70 Tetrahydrofuran 719
    Ghazi A. Dannan

    71 Perchloroethylene (Tetrachloroethylene) 727
    David G. Dodge and Julie E. Goodman

    72 Trichloroethylene 733
    David G. Dodge and Julie E. Goodman

    73 Acrylonitrile 741
    Jason M. Fritz and April M. Luke

    Section V Organic High Polymers, Monomers, and Polymer Additives 755
    Section Editor: Raymond D. Harbison

    74 Introduction 757
    Raymond D. Harbison

    75 Plastics 759
    Marek Banasik

    76 Elastomers 785
    Marek Banasik

    77 Synthetic Fibers 791
    Marek Banasik

    78 Bisphenol A (4,4´-Isopropylidenediphenol) 795
    Julie E. Goodman, Lorenz R. Rhomberg, and Michael K. Peterson

    79 Polystyrene/Styrene 809
    Leslie A. Beyer and Julie E. Goodman

    80 Phthalates 815
    Robert W. Benson

    81 Decabromodiphenyl Ethane 821
    Marek Banasik

    82 Tetrabromobisphenol A 827
    David Y. Lai

    83 Tris[2-Chloro-1-(Chloromethyl)Ethyl] Phosphate (TDCPP) 837
    Marek Banasik

    84 Tris(2-Chloro-1-Methylethyl) Phosphate (TCPP) 845
    Marek Banasik

    Section VI Pesticides 855
    Section Editor: Raymond D. Harbison

    85 Introduction 857
    Raymond D. Harbison

    86 Insecticides 859
    Carol S. Wood

    87 Herbicides 877
    Giffe T. Johnson

    88 Fungicides 901
    Amora Mayo-Perez and Raymond D. Harbison

    89 Rodenticides 917
    Daniel L. Sudakin

    Section VII Dusts and Fibers 927
    Section Editor: Raymond D. Harbison

    90 Introduction 929
    David R. Johnson

    91 Benign Dusts (Nuisance Dusts) 931
    Humairat H. Rahman and Raymond D. Harbison

    92 Fibrogenic Dusts 935
    Charles Barton

    93 Mixed Dusts 949
    Charles Barton

    94 Synthetic Vitreous Fibers 959
    Thomas Truncale and Yehia Y. Hammad

    95 Organic Dusts 969
    David R. Johnson

    96 Naturally Occurring Mineral Fibers 997
    Ali K. Hamade, Christopher M. Long, and Peter A. Valberg

    97 Nanoparticles 1025
    Daniel A. Newfang, Giffe T. Johnson, and Raymond D. Harbison

    Section VIII Physical Agents 1029
    Section Editor: Marie Bourgeois

    98 Radio-Frequency Radiation 1031
    R. Timothy Hitchcock

    99 Optical Radiation: Ultraviolet, Visible Light, Infrared, and Lasers 1045
    Joseph M. Greco

    100 Ionizing Radiation 1055
    Thomas A. Lewandowski, Juhi K. Chandalia, and Peter A. Valberg

    101 Electromagnetic Waves (EMF and RF) and Health Effects 1069
    Peter A. Valberg

    102 Traumatogens Associated with Carpal Tunnel Syndrome 1087
    Joan M. Watkins

    103 Vibration 1099
    Donald E. Wasserman

    104 Occupational Noise 1115
    David L. Dahlstrom

    105 Heat Stress Illness 1123
    Marie M. Bourgeois and David R. Johnson

    Section IX Special Topics 1129
    Section Editor: Raymond D. Harbison

    106 Mode of Action/Human Relevance Framework 1131
    M.E. (Bette) Meek

    107 Carcinogenesis 1135
    Carlos A. Muro-Cacho

    108 Genotoxicity Testing Strategies, Guidelines, and Methods 1173
    Ching-hung Hsu and Qingli Wang

    109 Human Relevance of Rodent Leydig Cell Tumors 1189
    Thomas J. Steinbach, Robert. R. Maronpot, and Jerry F. Hardisty

    110 Reproductive Toxicology 1197
    Judith W. Henck

    111 Developmental Toxicology 1229
    Thomas A. Lewandowski

    112 Ototoxicity 1241
    Matthew Mifsud and K. Paul Boyev

    113 Dermal and Ocular Toxicity 1247
    Jayme P. Coyle, Alison J. Abritis, Amora Mayo-Perez, Marie M. Bourgeois, and Raymond D. Harbison

    114 Reactive Airways Dysfunction Syndrome (RADS) 1259
    David J. Hewitt

    115 Pulmonary Sensitization 1263
    David J. Hewitt

    116 “Street” and Prescription Drug Abuse 1267
    Sharon S. Kelley, James Godin, and John Christie

    117 Mycotoxins 1283
    Clara Y. Chan and Bruce J. Kelman

    118 Phosphine 1295
    Michael W. Perkins, Benjamin Wong, Dorian Olivera, and Alfred Sciuto

    119 Diesel Exhaust 1301
    J. Michael Berg, Phillip T. Goad, and Thomas W. Hesterberg

    120 Spaceflight Operations 1311
    Michael A. Cardinale, Philip J. Scarpa, James R. Taffer, and Daniel Woodard

    121 Regulatory Toxicology 1321
    David M. Polanic and Marek Banasik

    Index 1331

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