Description
Book SynopsisThis textbook focuses on the nascent field of Immunoepidemiology that addresses how differences in immune responses among individuals affect the epidemiology of infectious diseases, cancer, hypersensitivity, and autoimmunity. The idea for the book originated from a course entitled “Immunology for Epidemiologists“ at the Yale School of Public Health. While many fine textbooks are available that address the immunological responses of individuals to pathogens, these provided very little information regarding how immunological variation among populations affects the epidemiology of disease. And yet, it has long been recognized that there is great immunologic diversity among people, which can have a profound effect on the epidemiology of disease. Careful review of the immunologic and epidemiologic literature revealed that there have been relatively few publications concerning immunoepidemiology and that no textbook is available on the subject. This textbook therefore aims to fill this void by providing a much-needed tool to comprehensively and efficiently teach immunoepidemiology. The book includes a section on the basic principles of immunology, and then applies them to particular examples of disease in human populations. The target audience for this text book are Masters of Public Health students. Others who should also find it of interest include PhD students in epidemiology, immunology, medical students, generalists, and specialists in immunology, infectious diseases, cancer, and rheumatology.
Table of ContentsSection I. Introduction
Chapter 1. Introduction to Immunology, Epidemiology, and Immunoepidemiology
Linda Niccolai, Nancy H. Ruddle, and Peter J. Krause
Chapter 2. Organization and Cells of the Immune System
Paula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhD
Chapter 3. Innate Immunity: Recognition and Effector Functions
Paula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhD
Chapter 4. Adaptive Immunity: Antigen Recognition by T and B Lymphocytes
Paula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhD
Chapter 5 Adaptive Immunity: Effector Functions, Regulation, and Vaccination
Paula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhD
Chapter 6. Disorders of the Immune System
Paula B. Kavathas, PhD, Peter J. Krause, MD, Nancy H. Ruddle, PhD
Chapter 7. Polymorphisms of Selected Components of the Innate and Adaptive Immune Systems
Nancy H. Ruddle and Paula B. Kavathas
Chapter 8. Immunoepidemiology of Immune Dysfunction
Eric Meffre, Peter J. Krause and Nancy H. Ruddle
Chapter 9. Immunoepidemiology of Mycobacterium tuberculosis
Camila D. Odio, Richard J. Bucala
Chapter 10. Host Immunity to Human immunodeficiency Virus Infection
Elijah Paintsil
Chapter 11. Fungal Immunoepidemiology
Marwan M. Azar
Chapter 12. Immunoepidemiology of Plasmodium falciparum Malaria
Amy K. Bei, Sunil Parikh
Chapter 13. Immunoepidemiology of Cancer
Xiaomei Ma, Rong Wang
Chapter 14. Modeling Approaches Toward Understanding Infectious Disease Transmission
Laura A. Skrip, Jeffrey P. Townsend
Chapter 15. Vaccines
Diane McMahon-Pratt
Chapter 16. Immunotherapy for Infectious Diseases, Cancer, and Autoimmunity
Peter J. Krause, Paula B. Kavathas, Nancy H. Ruddle
Appendix
Jane O'Bryan, Kara Fikrig, Peter J. Krause, Kate Nyhan
