Medical microbiology and virology Books
Springer Antibiotic Associated Diarrhoea and Colitis: The role of Clostridium difficile in gastrointestinal disorders
Book SynopsisAntimicrobial-associated diarrhea is often caused by Clostridium difficile; this disease can best be diagnosed by detection of fecal cytotoxin in a tissue culture assay and, when therapy is indicated, can be effectively treated with orally administered vancomycin. The cause of disease in most cases of antimicrobial-associated diarrhea that do not involve C. difficile is not known; fortunately, this form of diarrhea 1S usually mild. Antimicrobial-associated diarrhea may also rarely involve s. aureus and certain enteric pathogens. 37 QHAPTER 4 Qf. TECTlON. ISOLATION Al:iQ...IQENTlFICATlON OF CLOSTRIDIUM PIFFICILE S. P. BORRIELLO and PAULINE HONOUR Introduction 38 Detection of Co dlfflcile in stools 38 Direct methods 38 Indirect methods 39 Isolation of Co djfficjle 40 Identification of Co difflcile 44 38 DETECTION ISOLATION AND IDENTIFICATION OF CLOSTRIDIUM DIFFICILE S. P. Borriello and Pauline Honour Introduction In view of the mounting evidence generated world wide in the last few years that firmly implicates GBP. difficile as the aetiological agent in both antibiotic and non-antibiotic associated pseudomembranous colitis (Larson ~ al. , 1978, Bartlett ~ al. , 1978a, George ~ al. , 1978a), and also recent recognition of the fact that there may be a spectrum of gastrointestinal diseases associated with GBP. difficile infections (Borriello and Larson, 1981, Bolton ~ al. , 1980, Brettle ~ al. , 1982), an increasing number of laboratories are seeking to detect, isolate and identify GBP. difficile from clinical samples.Table of Contents1 Antibiotics associated with Clostridium difficile mediated diarrhoea and/or colitis.- 2 Spectrum of disease.- 3 Diagnosis and treatment of antimicrobial agent-associated diarrhea and colitis.- 4 Detection, isolation and identification of Clostridium difficile.- 5 Detection of Clostridium difficile toxins.- 6 Epidemiology of antimicrobial agent-associated diarrhea and colitis.- 7 Typing Clostridium difficile.- 8 Clostridium difficile and colonization resistance.- 9 Characteristics of the toxins of Clostridium difficile.- 10 Interaction of Clostridium difficile toxin B (cytotoxin) with cultured cells.- 11 Animal models of Clostridium difficile infection.- 12 The pathology of antibiotic-associated colitis.- Concluding remarks The unanswered questions.- Reference section.
£123.49
Springer Verlag, Singapore Gut Microbiota and Pathogenesis of Organ Injury
Book Synopsis This book aims to introduce the latest research in gut microbiota by systematically summarizing how it modulates the pathogenesis of organ injury including alimentary tract injury, liver injury, lung injury, brain injury, renal injury, heart and vascular injury, endocrine disorders, immune responses and multiple organ dysfunction syndrome (MODS) during sepsis. Gut microbiota which is recognized as a new “organ” in the body has been demonstrated to be able to regulate the homeostasis of many organs. The key role played by gut microbiota is the hotspot in biomedical research nowadays. This book provides a state-of-the-art report on recent discoveries regarding the novel insight into the mechanisms of human diseases progression. It will also offer the overall picture of the pathophysiologic roles of gut microbiota. This book is helpful for graduate students and professional researchers to get the knowledge of frontiers in both gut microbiota and organ injury.Table of ContentsIntroduction.- Gut microbiota and alimentary tract injury.- Gut microbiota and liver injury - Acute liver injury.- Gut microbiota and liver injury - Chronic liver injury.- Gut microbiota and lung injury.- Gut microbiota and brain injury.- Gut microbiota and renal injury.- Gut microbiota and heart, vascular injury.- Gut microbiota and endocrine disorders.- Gut microbiota and immune responses.- Gut microbiota and multiple organ dysfunction syndrome (MODS).
£999.99
National Geographic Society The Psychobiotic Revolution
Book Synopsis'A friendly, interesting, and up-to-date read on the science of the microbiome and the brain' - Psychology Today 'Compelling, engaging, and informative, this book teaches us why microbes may affect all of our decisions' - Jack Gilbert Ph.D., co-author of Dirt Is Good MEET YOUR MICROBES Written by the leading researchers in the field, this information-rich guide to improving your mood explains how gut health drives psychological well-being, and how depression and anxiety can be relieved by adjusting your intestinal bacteria. This groundbreaking book explains the revolutionary new science of psychobiotics and the discovery that your brain health and state of mind are intimately connected to your microbiome, that four-pound population of microbes living inside your intestines. Leading medical researchers John F. Cryan and Ted Dinan, working with veteran journalist Scott C. Anderson, explain how common mental health problTrade Review"More questions about gut, human health and disease? Try [The Psychobiotic Revolution]" –Psychology Today"This is an accessible guide for a lay audience on science that could radically alter the understanding of anxiety and depression, along with a host of other conditions." –Publishers Weekly “…I recommend reading The Psychobiotic Revolution by Scott C. Anderson.” –Forbes.com“Although decidedly aimed at the lay reader, the tone throughout is very humorous; I found myself swiftly turning pages, excitedly anticipating the next witty joke. Overall, this is a great book that encourages you to 'take charge of your gut to optimize your mind and your mood'. This is a book that you would reluctantly lend to friends, in the fear that they might not return it.” –Lancet "The hope is that it may one day be possible to diagnose some brain diseases and mental health problems by analysing gut bacteria, and to treat them – or at least augment the effects of drug treatments – with specific bacteria. Cryan and his colleague Ted Dinan call these mood-altering germs “psychobiotics”, and have co-written a book with the American science writer Scott C Anderson called The Psychobiotic Revolution." —The Guardian"The Psychobiotic Revolution could change how you think." —sultanabun.com"The authors of The Psychobiotic Revolution present clear research that we are indeed what we eat and that our lives would be much more enjoyable if we could balance our gut health in order to balance the rest of us." —Peppermint PhD. blog“This book is written for a lay person. It does a very good job of explaining some difficult concepts in a way that will be easily understood by people who don’t have any biology background without dumbing the subject matter down so much that people with more knowledge would cringe as they read it. That’s a fine line to walk.” –Spirit blog“Many of my burning questions were answered in a simple and succinct way that makes the battle to improve our health and diet much more feasible.” –Jathan & Heather blog“Packed with the latest scientific research, [the book] informs and fascinates” –Literary Quicksand blog“The authors have combined all the most significant information and then gleaned out the important issues that the reader needs to know in an extremely easy to read book, which becomes a real page-turner. This short book certainly relates to “You are what you Eat!” –Patricia’s Wisdom blog“This authoritative yet engaging book provides up-to-the minute research and practical advice on the gut-brain axis, perhaps the most exciting area of science today. Written by some of the leaders in the field, it gives terrific insight into what is going on in the gut, how to change it to improve mood, and the largely unappreciated links between mental health and the many other diseases now linked to the gut microbiome.”—Rob Knight, Director of the Center for Microbiome Innovation, University of California at San Diego, author of Follow Your Gut and coauthor of Dirt is Good“Anderson, Cryan and Dinan have infused life into cutting edge research that is often still mired in the scientific language…. The authors take on a near impossible task, to translate 150 years of research into the infinite complexity of human behavior and make it digestible. Compelling, engaging and informative, this book teaches us why microbes may affect all of our decisions…. This is brain food!”
£12.34
McGraw-Hill Education ISE Prescotts Principles of Microbiology
Book SynopsisPrescott''s Principles of Microbiology provides a balanced, comprehensive introduction to all major areas of microbiology. Because of this balance, Prescott''s Principles of Microbiology is appropriate for microbiology majors and mixed majors courses. The authors have focused on readability, artwork, and the integration of several key themes, including evolution, ecology and diversity, throughout the text, making an already superior text even better.Table of ContentsPart One Introduction to Microbiology1 The Evolution of Microorganisms and Microbiology2 Microscopy3 Bacterial and Archaeal Cell Structure4 Eukaryotic Cell Structure5 Bacterial and Archaeal GrowthPart Two Microbial Metabolism6 Introduction to Metabolism7 Catabolism: Energy Release and Conservation8 Anabolism: The Use of Energy in BiosynthesisPart Three Microbial Molecular Biology and Genetics9 Genome Replication10 Gene Expression11 Regulation of Cellular Processes12 Mechanisms of Genetic VariationPart Four The Diversity of the Microbial World13 Gram-Positive Bacteria14 Proteobacteria15 Nonproteobacterial Gram-Negative Bacteria16 Archaea17 Eukaryotic Microbes18 Viruses and Other Acellular Infectious Agents Part Six Host Defense and Pathogenicity22 Innate Host Resistance23 Adaptive Immunity24 The Human Microbiome and Host Interactions25 Infection and PathogenicityPart Seven Applied Microbiology26 Epidemiology and Public Health Microbiology27 Control of Microorganisms in the Environment28 Antimicrobial Chemotherapy29 Microbiology of Food30 Industrial and Environmental MicrobiologyPart Eight Methods in Microbiology31 Microbial DNA Technologies32 Microbial Genomics33 Methods in Microbial Biology34 Clinical Microbiology and Immunology
£56.04
Oxford University Press Microbiology
Book SynopsisModern microbiology has transformed our understanding of life on earth, and had a huge impact on medicine, agriculture, and biotechnology. In this Very Short Introduction, Nicholas P. Money explores the microbial world, considering its diversity and vital roles in ecosystems, including the human body.Trade ReviewFor individuals from all backgrounds who need a succinct yet complete introduction to microbiology, this book is an ideal resource, and readers can use this book as a springboard into a wide variety of other topics in microbiology by using the resources for further reading provided at the end of the book. * R. K. Harris, CHOICE *Table of Contents1. Microbial diversity ; 2. How microbes operate ; 3. Molecular microbiology ; 4. Viruses ; 5. Microbiology of human health and disease ; 6. Microbial ecology and evolution ; 7. Microbes in agriculture and biotechnolohy ; Further reading ; Index
£9.49
Marion Boyars Publishers Ltd Death A New Perspective on the Phenomena of
Book Synopsis
£9.95
Bloomsbury Publishing PLC Getting to Zero: A Doctor and a Diplomat on the
Book SynopsisIn 2014, a 28-year old British doctor found himself co-running the Ebola isolation unit in Sierra Leone’s main hospital after the doctor in charge had been killed by the virus. Completely overwhelmed and wrapped in stifling protective suits, he and his team took it in turns to provide care to patients while removing dead bodies from the ward. Against all odds he battled to keep the hospital open, as the queue of sick and dying patients grew every day. Only a few miles down the road the Irish Ambassador and Head of Irish Aid worked relentlessly to rapidly scale up the international response. At a time when entire districts had been quarantined, she travelled around the country, and met with UN agencies, the President and senior ministers so as to be better placed in alerting the world to the catastrophe unfolding in front of her. In this blow-by-blow account, Walsh and Johnson expose the often shocking shortcomings of the humanitarian response to the outbreak, both locally and internationally, and call our attention to the immense courage of those who put their lives on the line every day to contain the disease. Theirs is the definitive account of the fight against an epidemic that shook the world.Trade ReviewGetting to Zero is a compelling read, full of compassion, grief, ingenuity and stories of courage and unstinting commitment of local nurses, cleaners and others who remain unsung heroes of Ebola. But it is also full of tales of denial, extraordinary lapses in leadership and awkward truths that will make uncomfortable reading for many, locally and internationally. * Guardian *Written in an honest and engaging tone, their experience behind the scenes of the outbreak is illuminating and highlights important lessons for the management of future outbreaks, and the operational errors that increased the number of lives lost in the west African outbreak of 2014–16. * Lancet *Hundreds of reports have been written on the 2014 epidemic – the most widespread Ebola outbreak since the virus was discovered – but none is nearly as insightful, compassionate or unsparing as this. * Irish Times *A brave, bold, yet humble account from the frontlines of the Ebola outbreak in Sierra Leone. This is vital reading to help us all do better next time. * David Miliband, President and CEO of the International Rescue Committee *Courage in extreme clinical danger, courage to challenge obstructive bureaucracy, courage to make tough decisions and the courage to endure. This is the courage that Sinead Walsh and Oliver Johnson displayed in Sierra Leone. Their compelling book is essential reading for all who care about global health. * Eldryd Parry, founder of the Tropical Health and Education Trust *A captivating and brutally honest account of the Ebola epidemic from two brave, committed individuals who unexpectedly found themselves at its epicentre. The authors pull no punches, and leave us asking: will these lessons be learned, or will the world once again forget and move on? * Jeremy Farrar, Director of the Wellcome Trust *This powerful book asks important questions about aid and development and offers insights that everyone working in global health should absorb – as well as being a personal and very moving account of an epidemic that killed thousands. * Lord Nigel Crisp, Co-Chair of the All Party Parliamentary Group on Global Health *Walsh and Johnson represent the best of international intervention. This book reveals the complexities and level of cooperation that made “getting to zero” possible. Offers excellent insight into those trying times. * O.B. Sisay, Director of the Situation Room at the National Ebola Response Centre, Sierra Leone *An extraordinary account from the thick of the battle against Ebola. This is history’s first draft, and a powerful example of persistent and pragmatic leadership. Mandatory reading for anyone concerned with global health in the broadest sense. * Paul Farmer, Harvard Medical School, and co-founder of Partners in Health *Takes us behind the scenes to the harrowing frontlines of the Ebola epidemic – highlighting a set of lessons that an inter-connected world would ignore at our peril. A compelling read. * Samantha Power, former US Ambassador to the UN *A detailed, up-close-and-personal perspective on the Ebola epidemic in Sierra Leone, important for all who want to understand what it is to confront a terrible health threat. * Tom Frieden, President and CEO of Resolve to Save Lives, and former Director of the Centers for Disease Control and Prevention *Johnson and Walsh provide a frank, beautifully written, and essential guide to the lessons learned from the heart of the outbreak. Their first-hand experiences in battling this terrible disease will take your breath away. A must read. * Tulip Mazumdar, Global Health Correspondent for BBC News *Table of ContentsMaps Preface 1. New Beginnings: Sierra Leone before the Outbreak of Ebola 2. A Dubious Start: Ebola in Guinea 3. Ebola Emerges in Sierra Leone 4. Kenema Explodes 5. Armageddon 6. The Long Wait for Action 7. The Response Kicks Off 8. The Response Bears Fruit 9. Getting to Zero 10. Conclusion Afterword: If We Had to Do It All Again…
£15.19
CABI Publishing Descriptions of Medical Fungi
Book SynopsisThe 4th edition of this book provides laboratory staff and clinicians with a quick benchtop reference on the identification and antifungal susceptibility of human and animal fungal infections. It contains descriptions of all the major medical fungal pathogens, 179 species from 109 genera. This updated edition includes new and revised descriptions and he authors have reconciled current morphological descriptions and name changes with more recent genetic data. The most common fungal species are described, including members of the yeasts, mucoromycetes, conidial moulds, dimorphic pathogens, and dermatophytes. The book features:updates to taxonomy and fungal names.more than 350 colour photographs. antifungal susceptibility profiles, including for new drugs where available.methods of identification including molecular and/or MALDI-ToF mass spectroscopy.This handy reference is essential for laboratory staff and clinicians dealing with the identification and management of human and animal fungal infections, researchers in medical microbiology and mycology laboratories.
£112.32
Chelsea Green Publishing Co Corona, False Alarm?: Facts and Figures
Book SynopsisDoes the race for vaccine development make sense? What are the chances of success? Will the vaccine be safe? Will people accept it?? In June 2020, Corona, False Alarm? exploded into the German market, selling 200,000 copies and 75,000 e-books in the first six weeks. No other topic dominates our attention as much as coronavirus and COVID-19, the infectious disease it triggers. There’s been a global deluge of contradictory opinions, fake news, and politically controlled information. Differing views on the dangers posed by the pandemic have led to deep division and confusion, within governments, society, and even among friends and family. In Corona, False Alarm?, award-winning researchers Dr. Sucharit Bhakdi and Dr. Karina Reiss give clarity to these confusing and stressful times. They offer analysis of whether radical protective measures—including lockdown, social distancing, and mandatory masking—have been justified, and what the ramifications have been for society, the economy, and public health. Dr. Bhakdi and Dr. Reiss provide dates, facts, and background information, including: How Covid-19 compares with previous coronaviruses and the flu virus What infection numbers and the death rate really tell us The challenges around lockdown: Were the protective measures justified? Mandatory mask-wearing: Does the science support it? Vaccines: What are the chances of success? What are the risks? Corona, False Alarm? provides you with sound information and substantiated facts—and encourages you to form your own opinion on the corona crisis.
£10.44
Cambridge University Press New Challenges to Health The Threat of Virus Infection 60 Society for General Microbiology Symposia Series Number 60
a huge range and FREE tracked UK delivery on ALL orders.
£89.29
Cambridge University Press Human Herpesviruses Biology Therapy and
Book SynopsisThis comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, EpsteinâBarr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.Table of ContentsPart I. Introduction; Part II. Basic Virology and Viral Gene Effects on Host Cell Functions; Part II. Basic Virology and Viral Gene Effects on Host Cell Functions; Part II. Basic Virology and Viral Gene Effects on Host Cell Functions; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part III. HHV- 6a, 6b and 7 Ann Arvin and Richard Whitley; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part IV. Non-Human Primate Herpesviruses Ann Arvin, Patrick Moore and Richard Whitley; Part V. Subversion of Adaptive Immunity Richard Whitley and Ann Arvin; Part VI. Antiviral Therapy Richard Whitley; Part VII. Vaccines and Immunotherapy Ann Arvin and Koichi Yamanishi; Part VIII. Herpes as Therapeutic Agents Richard Whitley and Bernard Roizman.
£498.60
Cambridge University Press Microbevector Interactions in Vectorborne Diseases 63 Society for General Microbiology Symposia Series Number 63
a huge range and FREE tracked UK delivery on ALL orders.
£67.44
Cambridge University Press Gene Expression Profiling by Microarrays
a huge range and FREE tracked UK delivery on ALL orders.
£168.15
Nova Science Publishers Inc Noroviruses: Outbreaks, Control & Prevention
Book SynopsisNoroviruses are responsible for approximately 90% of epidemics worldwide; in particular, non-bacterial outbreaks of gastroenteritis in humans around the world, causing approximately 200,000 deaths annually in developing countries. In addition, after the introduction of rotavirus vaccination programs, the norovirus is the most common cause of paediatric gastroenteritis, requiring medical care in the high- and middle-income countries. All of this information is indicative of norovirus prevalence worldwide, and of the necessity of efforts to develop effective tools for their control and prevention. The prevalence of noroviruses worldwide is alarming, and this information is indicative of the necessity for effective tools to aid in their control and prevention. This book presents a compilation of recent research on these aspects, providing essential and specific information to help further understand the prevalence and distribution of norovirus genotypes and strains, the potential emergence of new strains of this pathogen, as well as strategies for their prevention and treatment.
£148.79
Nova Science Publishers Inc Zika Virus: Basic Biology, Symptoms,
Book SynopsisThe bubonic plague, smallpox, HIV/AIDS, malaria, and influenza are some of the worst epidemics/pandemics that afflicted human beings from antiquity to modern times, killing millions of people. The mosquito-borne human-infecting viruses, rotavirus, and the seasonal influenza regularly affect lives across continents in the millions. Currently, we are facing various disease-inducing organisms of the Flavivirus family the Yellow fever virus (YFV), West Nile virus (WNV), Japanese encephalitis virus (JEV), Tick-borne encephalitis virus (TBEV), Dengue virus (DENV) and Zika virus (ZIKV). Zika virus was first isolated from a febrile rhesus monkey in the Zika forest of Uganda in 1947. It drew out heightened attention following the large number of microcephaly in newborn babies in Latin America in 2015. On 1 February 2016, WHO declared that the association of Zika infection with clusters of microcephaly and other neurological disorders constituted a Public Health Emergency of International Concern. Although the severity and number of ZIKV afflicted cases have gone down lately, the public health community worldwide is keeping a watchful eye on it. ZIKV is an enveloped virus with a positive-sense RNA genome that translates into a single polypeptide, which then gets cleaved into three structural and seven nonstructural viral proteins. As compared to the earlier centuries, we have an expanding repertoire of diverse and fast acting technologies available at our hand to manage and mitigate emerging diseases. Completion of the Human Genome Project has given rise to sequencing methods which can quickly determine the genetic sequence of an alarming pathogen. Following Moores law, the power of computers, essential for data analysis and visualization, has grown substantially with time. The combination of genomic data of pathogens, computational modeling methods, and data driven methodologies can lead to a generic approach of surveillance, mitigation, vaccine design as well as new drug discovery for emerging pathogens. The four pillars of this may consist of: a) Epidemiological approaches for the characterization of carriers of next possible emerging pathogens; b) Fast computational sequence comparison methods for the characterization of emerging pathogens to understand how novel or severe they could be; c) Once the sequences of the pathogen have been determined, computer-aided vaccine design (CAVD) methods can be used to suggest a set of probable vaccine candidates for quick synthesis and testing in the laboratory; and d) Computer-assisted design of novel therapeutics and their laboratory testing as well as repurposing of already existing FDA-approved drugs. A combination of different classes of methods in vivo, in vitro and in silico will be needed to tackle suddenly emerging viruses like the Zika virus. As in many other fields of biomedical research, high throughput and low cost in silico technologies may provide the first line of defense against such emerging pathogens providing decision support systems for the judicious applications of medium throughput in vitro methods and low throughput as well as costly in vivo techniques. An emerging trend in many scientific disciplines is a strong tendency of being transformed into some form of information science. The editors of this book sincerely hope that the four-pronged computer-assisted approach described in this book will help in managing and mitigating emerging infectious diseases like Zika.
£999.99
Nova Science Publishers Inc Ebola Virus Disease (EVD): Outbreaks, Control and
Book SynopsisTo mitigate the spread of the rare and deadly disease Ebola, Ebola Virus Disease (EVD): Outbreaks, Control and Prevention Strategies begins with the proposition of a mathematical model with vital dynamics and two preventive measures: quarantine and isolation. Humanitarian issues in Ebola prevention and control are explored, as well as the cultural practices and social norms during outbreaks. Additionally, some innovative approaches in the humanitarian response to prevention and control are discussed. The authors expose the dilemma Ebola poses to within the healthcare system, where healthcare providers are caught between the over-arching quest for self-preservation from a highly virulent disease and the professional demand of prioritising the interests of the patients over self. In conclusion, the authors describe successfully developed drug candidates from their laboratory for the treatment Ebola using EBOV protein structure, such as VP24, VP35, VP40, nucleoprotein, and glycoprotein.
£62.04
Nova Science Publishers Inc West Nile Virus: Outbreaks, Control and
Book SynopsisThe opening study included in West Nile Virus: Outbreaks, Control and Prevention Strategies aims to design and implement an efficient data-driven agent-based model of West Nile virus spread, considering highly-mobile humans with a high level of heterogeneous properties. The authors propose a cellular difference equation model for adoption in West Nile virus-agent-based models. Following this, the authors summarize the envelope domain III protein, its production using various host systems, and applications in the development of West Nile virus vaccines and diagnostics. Lastly, this collection reviews the impacts of West Nile virus on several bird species, and discusses the implications for the long-term survival the Yellow-billed Magpie.Table of ContentsPrefaceMulti-Species, Climate-Driven and Landscape-Based Cellular Difference Equation Model for West Nile Virus: Toward an Agent-Based Model of West Nile Virus SpreadRecombinant Envelope Domain III Protein of West Nile Virus: Recent Developments and ApplicationsImpacts of West Nile Virus on the Yellow-Billed Magpie and Other Birds in Californias Central ValleyIndex.
£62.04
Nova Science Publishers Inc A Closer Look at Antibiotic Resistance
Book SynopsisBacterial infections have become more difficult, and sometimes impossible, to treat due to antibiotic resistance, which occurs when bacteria develop the ability to defeat the available drugs designed to kill them. According to the Centers for Disease Control and Prevention, each year, 2 million Americans become sick with antibiotic-resistant infections, and of that, about 23,000 die. This book examines the challenges related to antibiotic resistance, the development and use of diagnostic testing to identify antibiotic resistance, the development of treatments for resistant infections, and appropriate antibiotic use.Table of ContentsPreface; Antibiotic Resistance: Additional Federal Actions Needed to Better Determine Magnitude and Reduce Impact; Combating Superbugs: U.S. Public Health Responses to Antibiotic Resistance; Index.
£138.39
Nova Science Publishers Inc Focus on Arbovirus Infections
Book SynopsisArthropod-borne disease is a common health problem all over the world. The term "arboviral diseases" means the arthropod-borne arboviral infections. The purpose of this book is to summarise and present the topics specifically relating to the mosquito-borne disease that is unique in the tropical countries. Due to the globalisation in the present day, the change in the epidemiology of diseases from one site to the others all around the world can be expected. The summative on the common arboviral diseases can be and should be performed. This book can make them at least realise and familial with the problems. The book covers specifically the clinical aspect, scientific laboratory aspect, public health aspect as well as the social sciences relating to important arboviral infectious diseases. The common arboviral diseases are summarised, presented and discussed. Mainly the book presents summative data from the molecular to the population scales, as well as additional metanalysis for important topics. In addition, the diagnostic guideline and clinical practice guideline of the mentioned conditions will be presented. This work can be a useful reference material for the practitioners who are not familiar to the unique problems of the developing world and might face up with those problems due to the possible migration of diseases. The academic level of this book is aimed to be for the wide range from the medical student, resident, general practitioner, specialist in infectious and tropical medicine and the researchers in medical sciences. It can also be useful for the medical personnel in allied health sciences.
£73.49
Nova Science Publishers Inc Pseudorabies (Aujeszky's Disease) & Its
Book Synopsis
£92.99
Nova Science Publishers Inc Mushrooms: Types, Properties & Nutrition
Book Synopsis
£185.99
Nova Science Publishers Inc Encyclopedia of Virology Research: 2 Volume Set
Book SynopsisThis book presents current research in the field of virology. Topics discussed include giant viruses and their genomes; replication, transcription and translation of coronaviruses; dengue detection, diagnosis and control; dengue virus pathogenesis and animal modeling; molecular diagnostics for detecting dengue; interspecies transmission of avian influenza virus to dogs; conventional and experimental vaccines against avian influenza; molecular pathogenesis of avian influenza and the prospect of therapy using small interfering RNA and U.S. and international responses to the global spread of avian flu.
£999.99
Nova Science Publishers Inc Parvovirus B19 & Hematological Disorders in
Book SynopsisParvovirus B19 is a childhood infectious disease of global proportions. It is the leading cause of erythema infectiousum, affecting mainly young age children. This new book outlines the recent advances in understanding Parvovirus infections in children particularly associated hematological consequences. Also, it describes the associated complications by in utero infection such as hydropes fetalis and acute leukaemia. It has emerged as an occupational viral infection both to health care workers and school workers. It carries the danger of serious infection of recipients of blood and blood products transfusion.
£92.99
Nova Science Publishers Inc Microbiology & Molecular Biology Researcher
Book SynopsisThis book compiles biographical sketches of top professionals in the field of microbiology and molecular biology, as well as research summaries from a number of different focuses in these important fields.
£189.74
Nova Science Publishers Inc Fungi: Types, Environmental Impact & Role In
Book Synopsis
£278.99
Nova Science Publishers Inc Hepatitis C & Liver Transplantation
Book SynopsisChronic Hepatitis C virus (HCV) infection is a serious condition affecting over 180 million people world-wide. The virus infects the liver and while it is estimated that 20% of those infected clear the virus spontaneously, the virus persists in the majority of individuals leading to liver fibrosis, cirrhosis, and hepatocellular carcinoma. This book presents topical research in the study of the epidemiology, pathogenesis and treatment of Hepatitic C Virus including: genome-wide association studies regarding HCV infection; hepatic and blood dendritic cell subsets in patients with chronic HCV; bone metabolism disorders in HCV infection; Socs1 involvement in liver damage during HCV infection; asymptomatic low-level HCV persistence; and HCV infection as the leading cause of liver disease in renal transplant recipients.
£106.49
Nova Science Publishers Inc Alimentary Microbiome: A PMEU Approach
Book Synopsis
£152.99
Nova Science Publishers Inc Salmonella: Classification, Genetics & Disease
Book Synopsis
£146.24
Nova Science Publishers Inc Hepatitis B: New Research
Book SynopsisHepatitis B virus (HBV) infection is a problem of global health importance and represents a significant cause of morbidity and mortality world-wide. HBV can be transmitted parenterally, sexually and perinatally. Despite progress on prophylaxis, diagnostic and treatment of HBV infection, it remains one of the major causes of chronic liver disease, cirrhosis or hepatocellular carcinoma. This book presents a compilation of current research including such topics as Hepatitis B and dialysis; Hepatitis B virus infection among middle school students in South Brazil; genotyping and management of chronic Hepatitis B; the risk assessment for Hepatitis B infection and its role in hepatocellular carcinoma; and silencing Hepatitis B virus replication with antiviral Pri-Mir shuttles generated from liver-specific Pol II promoters.
£106.49
Nova Science Publishers Inc Parvovirus B19 & Hematological Disorders in
Book Synopsis
£53.59
Nova Science Publishers Inc Sex Chromosomes: New Research
Book SynopsisIn this book, the authors present new research in the study of sex chromosomes. Topics discussed in this compilation include the evolution of mammalian X chromosomes and X chromosome inactivation; the role of sex chromosomes in mammalian female fertility; the fate of the Y chromosome; the role of Y chromosome genes on tumour development risk in disgenetic gonads; deletion of amelogenin Y-locus; non-invasive prenatal diagnosis for foetal sex determination; and application of X chromosomal STR polymorphisms to individual identification.
£139.49
Nova Science Publishers Inc Avian Influenza: Molecular Evolution, Outbreaks &
Book SynopsisAvian influenza or bird flu refers to "influenza caused by viruses adapted to birds". Of the greatest concern is the highly pathogenic avian influenza (HPAI). Most human contractions of the avian flu are a result of either handling dead infected birds or from contact with infected fluids. In this book, the authors discuss the molecular evolution, outbreaks and prevention/control of avian influenza. Topics include the risk assessment of highly pathogenic avian influenza virus infections through water; biosecurity measures against highly pathogenic avian influenza (HPAI) in free-range flocks and commercial poultry in developing countries; outbreak control and viral evolution of the highly pathogenic H5N1 avian influenza in Thailand; and the changes in perceptions and attitudes that were identified in a follow-up survey conducted when bird flu was not the focus on widespread media coverage in Australia.
£92.99
Nova Science Publishers Inc Glutathione: Biochemistry, Mechanisms of Action &
Book SynopsisGlutathione (γ-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol found in both prokaryotic and eukaryotic organisms. GSH has potent electron-donating capacity that renders GSH both a potent antioxidant and a conventional cofactor for enzymatic reactions. GSH participates in many cellular functions such as redox control, stress defense, drug detoxification and cell signaling including regulation of DNA and protein synthesis, gene expression, apoptosis and cell proliferation. GSH concentration in the cell is homeostatically controlled, being continually self-adjusting with respect to the balance between GSH synthesis, its recycling from GSSG and its utilization by other enzymes. Alterations in its concentration contribute to oxidative stress, which plays a key role in aging and the pathogenesis of many diseases associated with redox processes modulation. This book discusses cutting-edge developments and deals with the information gained over the last few years on the physiological, biochemical and molecular roles of the GSH and its significance in mammalian, microbial and plant cells.
£206.24
Nova Science Publishers Inc Animal Models in Cancer Research & Human Disease:
Book SynopsisThis book discusses the applications, outcomes and controversies of using animal models in cancer research and human disease. Topics include murine models of sporadic and inflammation-related colon carcinogenesis with particular focus on the AOM/DSS chemically induced colorectal cancer model; large animal models of human cardiovascular disease; developments of cell therapeutic strategies for Alzheimer''s disease using animal models; the techniques and limitations of murine models of human colorectal cancer; animal models for antineoplastic chemotherapy-induced alopecia; and development of columnar-lined oesophagus with or without goblet cells in rate duodengastroesophageal reflux models through gut regenerative cell lineage (GRCL).
£159.74
Nova Science Publishers Inc Ribosomes: Molecular Structure, Role in
Book SynopsisRibosomes are essential protein-RNA complexes that synthesize proteins according to the gene library of the cell in all living organisms. In this book, the authors present current research in the study of the molecular structure, biological functions and implications for genetic disease of ribosomes. Topics include ribosomal alterations and immune-related illness; the role of ribosomes in mediating hypoxia response and tolerance in eukaryotes; the potential biomedical use of ribosome-inactivating proteins; coarse-graining the nano-machine ribosome to elucidate its functional dynamics; and structural aspects of ribosomal ligands interactions providing the work of the human translational machinery.
£159.74
Nova Science Publishers Inc Applications of Microbial Genes in Enzyme
Book SynopsisEnzymes are necessary for nearly all of life''s chemical reactions. With the advance of biotechnology, increasing numbers of enzymes are identified and over-produced prior to application in various industries that encompass medicine, agro-industry, commodity products sectors, and biofuel biotechnologies. Many enzymes currently are derived from recombinant micro-organisms. Enzyme manufacturers take advantage of new genetic techniques to develop and manufacture enzymes with improved properties. Such enzymes often originate from micro-organisms that cannot be readily cultured under laboratory or industrial conditions. By judicious selection of host micro-organisms, recombinant production strains can be constructed to allow efficient production of enzymes that are substantially free of undesirable enzymes or other microbial metabolites. The developments in molecular genetics and cell biology in the last four decades have reshaped enzyme production. This book provides comprehensive material on applications of important microbes and their gene functions in enzyme technology for audiences across many disciplines.
£245.99
Nova Science Publishers Inc Cryopreservation: Technologies, Applications &
Book SynopsisCryopreservation is a process where cells or whole tissues are preserved by cooling to sub-zero temperatures, typically 77 K. At these cold temperatures, any biological activity, including the biochemical reactions that would cause cell death, is effectively stopped. In this book, the authors discuss the technologies, applications and risks/outcomes of cryopreservation. Topics include cryopreservation of filamentous fungi; differential scanning calorimetry as a useful tool for understanding crystallisation and slow-freezing protocols; alternatives to cryopreservation for the short and long-term storage of mammalian cells; and mathematical modelling and simulations in the cryopreservation of living cells.
£139.49
Nova Science Publishers Inc Microcosms: Ecology, Biological Implications &
Book SynopsisIn this book, the authors discuss the ecology, biological implications and environmental impact of microcosms. Topics include using microcosms to investigate aspects of plant-bacterial interactions and bacterial evolution; multifactorial microcosm experiments to predict how plant species and assemblages respond to changes in the availability and spatio-temporal heterogeneity of resources like water, light and nutrients; development and optimisation of an aquatic laboratory microcosm for ecotoxicological risk assessment; assessment on transformation of organic pollutants in microcosms; bacterial evolution in simple microcosms; ecology and environmental side-effects of pesticides in tropical microcosms; floating dish microcosms to study the developments of biofilm communities; the role of semiosis and cohesion and sustainability inside microcosms; and soil microcosms and biogeographical research.
£159.74
Nova Science Publishers Inc Weeds as an Alternate Host of Geminivirus
Book SynopsisThe book represents basic information about viral-caused and viral-like diseases in many weeds. Many scientific reports have demonstrated that weeds serve as a reservoir or alternative hosts for geminivirus genera (eg: Begomovirus) for survival and spread in the absence of main crops. This book represents a tip of the iceberg of the diversity of begomoviruses in weeds. The recognition that geminivirus strains are capable of rapidly diverging through multiple mechanisms, underscores the need for accurate molecularly based methods that permit detection and tracking of biologically significant variants. Molecular approaches must combine knowledge of biology, ecology and the ability to monitor both conserved sequences and specific sites, most likely to undergo alteration with phylogenetic predictions to facilitate accurate identification and tracking of begomovirus variants and to also recognise new or resurgent viruses. Establishing databases of baseline sequences for extant viruses will permit future comparisons in establishing and interpreting disease patterns and associated trends for vector populations. With the development of reliable computational recombination detection tools and an increasing number of available genome sequences, many studies have reported evidence of recombination in a wide range of virus genera. The book also focuses on the first geminivirus database (GVDB) that contains biotic, molecular and in silico information which will permit rapid and accurate begomovirus identification and the selection of relevant viral species for the development of disease resistance/management strategy to the geminiviruses specific to individual crop production areas. To close, there is one chapter on the international and national status of geminivirus infection in various host weeds. Furthermore, the book''s heart discusses the most recent cutting-edge of research that makes this book essential reading for everyone, from researchers to scholars to students, working with molecular and computational aspects of geminivirus research as well as scientists already familiar with the area.
£999.99
Nova Science Publishers Inc Contribution of Microbiota to the Innate &
Book Synopsis
£135.19
Nova Science Publishers Inc Recent Advances in Toxoplasmosis Research
Book SynopsisToxoplasmosis is one of the most important food-borne illnesses and foetal maternal inflammatory syndromes. Currently, there is no safe and effective approved therapy against foetal maternal complication or persistent chronic infection. Toxoplasma is an intracellular organism. About 1.5 billion people world-wide are predicted to have toxoplasmosis, frequently with unknown lifelong health consequences. Toxoplasma is classified as "Category B pathogen" according to the Center for Disease Control (CDC) and National Institute of Health (NIH). The organisms reside in muscles and brain in cyst forms for the lifetime of the host awaiting reactivation. This book discusses several topics which include foetal and maternal toxoplasmosis; toxoplasma gondii and suicide and homicide; toxoplasmosis in several animals including cattle, goats, swine, dogs, and kittens; and molecular diagnosis in toxoplasmosis.
£119.99
Nova Science Publishers Inc Microbiological Clinical Hygiene
Book SynopsisThis book describes the issues of human health and healthcare from the point of view of hygiene monitoring and maintenance. Also, the perspectives on the effects of microbial cell structures, metabolism, communities and interactions on health and hygiene are included. Besides microbiological screening of patients, surfaces, air space etc. this book introduces some key bacteriological, virological and fungal risks in the clinical setting. It describes routes of contamination inside hospitals, and into our body. The means for prevention of the spreading of unwanted microbes are presented as well. Protection mechanisms of the bodily system and the balances of the human microbiome are discussed with respect to intrusions via the respiratory or digestive systems or damaged skin. The risks during operations or invasive treatments are highlighted, together with means for avoiding them. Examples of biofilm formation on the devices or on the body surfaces, latent infections, contagion mechanisms, as well as prevalent risks such as mycobacterial infections, antibiotic resistant strains, intracellular pathogens, nosocomial viruses, lowered host defences, Clostridium difficile, salmonellas, legionellas are included in the chapters of this book. Important developments such as personalized medicine, point-of-care diagnostics, arthroscopy, improved drug delivery, pre- and probiotic treatments, monitoring of the normal flora and its beneficial effects are also discussed.
£209.59
Nova Science Publishers Inc Ebola: Essentials, Response Efforts & Prevention
Book SynopsisThe Ebola virus is named after the Ebola River, near where the virus was discovered in 1976 in Zaire, now known as the Democratic Republic of the Congo (DRC). It is in the filovirus family, so called because of its filamentous shape. EVD is also known as Ebola haemorrhagic fever. The disease sometimes causes haemorrhage (ie: bleeding) from body openings, but this symptom is not consistent. Five strains of Ebola virus have been identified. This book discusses the essentials, response efforts, and prevention issues involved with the Ebola virus.
£131.19
Nova Science Publishers Inc Hemorrhagic Fever: Epidemiology, Clinical
Book SynopsisViral hemorrhagic fevers (VHFs) represent a collection of illnesses caused by several distinct viral families. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause life-threatening diseases. The chapters of this book discuss the consequences of the Ebola outbreak in West Africa; the most frequency imported infection worldwide (malaria); the reservoirs of selected infectious diseases (often bats and fruit bats); the clinical symptoms of viral diseases and the most widely used diagnostic methods for the correct identification of the pathogen involved; and a discussion on Japanese encephalitis (JE) as an infectious disease caused by a virus transmitted by blood-sucking arthropods.
£92.79
Nova Science Publishers Inc Mycotoxins: Occurrence, Toxicology & Management
Book SynopsisExposure to certain types of mycotoxins, the bioactive secondary metabolites of filamentous fungi, significantly impact the animal industry as well as human health. The contamination of food with mycotoxins is a worldwide problem in animal production and direct consequences are the reducing of food intake and production. In this book, the authors increase the public awareness of the implications of certain types of mycotoxins exposure to promote the health of livestock as well as the general public; an analysis of trichothecens (TCEs), a large group of mycotoxins, and their impact on lifestock health and production are also examined, as well as the occurrence of mycotoxins in animal products such as goat milk. Different strategies implemented for the analysis of a wide spectrum of mycotoxins, as well as their advantages and disadvantages are provided by the authors. In the next few chapters, the occurrence of mycotoxins in cereals and cereal products and in particular, their toxic properties are looked at; a discussion on deoxynivalenol (DON) and related 8-ketotrichothecene mycotoxins, which are extensively distributed in cereal-based foods and feed stuffs worldwide are reviewed; potential toxigenic fungi from diverse habitats are identified with special emphasis on the methods as well as on the genetic markers employed; the importance of performing exposure assessments to Aflatoxin B and some of the most important aspects to consider in the risk assessment process, including the simultaneous presence of other mycotoxins and the challenge of choosing the most suitable method to perform exposure assessment are analyzed; and finally, a review of the occurrence of dietary mycotoxins in Africa as well as the advances in analytical methods of mycotoxin extraction and detection over the last decade is provided.
£195.19
Nova Science Publishers Inc Pathogenic Bacteria: Pathogenesis, Virulence
Book SynopsisAlthough most forms of bacteria are harmless, pathogenic bacteria can cause disease and as such these microorganisms warrant scientific attention. Chapter One describes the virulence problem caused by extracellular polymeric substances and antibacterial compounds capable of inhibiting their production, biofilm formation, and bacterial pathogenicity. Chapter Two provides an overview of biophysical techniques that can validate targets of phytochemicals with anti-virulence properties that can help elucidate their mode of action. Chapter Three discusses terpenes'' anti-virulence modes of action, inhibition of biofilm, disruption of the cell wall and bacterial membrane, intercellular leakage, interruption of nucleic acids transcription, and interference with the quorum sensing signaling process. Chapter Four investigates the anti-pathogenic potential of essential oil from the plant asafoetida obtained through microwave-assisted extraction method. Finally, Chapter Five deals with the effect of audible sound waves on bacteria.
£999.99
Scientific Publishing Limited Common Cold vs the Flu Paper Poster
Book SynopsisDesigned as reference material to increase knowledge of the human body. Beautiful full-colour illustrations help enhance understanding of the body or illness. Suitable for healthcare professions, patients, students, educators and parents.
£14.59
Scientific Publishing Limited Common Cold vs the Flu Laminated Poster
Book Synopsis
£145.14
