Medical microbiology and virology Books
Nova Science Publishers Inc West Nile Virus: Overview & Abstracts
Book SynopsisBefore 1999, the West Nile Virus was unknown in the Western hemisphere. Since then, however, each summer has shown it moving progressively across the United States starting in New York. Such recurrent and steady movement means that the virus is here to stay. Transmitted by the bite of infected mosquitoes, the disease causes encephalitis, which is inflammation of the brain. Although most cases are relatively mild and include symptoms like a fever and skin rash, those with more severe cases can exhibit convulsions, muscle weakness, and paralysis. Some cases even prove fatal. There is no specific treatment for the virus, with most therapy coming under hospital oversight. In working to prevent the disease, several areas have taken to spraying against mosquitoes and recommended the use of insect repellent. Nonetheless, the virus continues to show itself and has become a regular, but still dangerous, routine of life. This book gives a useful overview of a disease that nobody knew much about a few short years ago, but is now making headlines. Carefully selected abstracts of virus-related literature follow as do accessible author, title, and subject indexes. For the study of the West Nile Virus, this book is a valuable resource.
£53.59
Nova Science Publishers Inc Septic Shock: Current Pathogenetic Concepts,
Book SynopsisSepsis is one of the most frequent complications in the surgical patient and one of the leading causes of mortality in intensive care units. During the past two decades, a great deal has been learned about surgical bacteriology, antibiotic prophylaxis, supportive management, and the host response to microbial invasion. Sepsis can be caused by infection with gram-negative bacteria, gram-positive bacteria, fungi (and particularly Candida), or viruses. Sepsis may also occur in the absence of detectable bacterial invasion, and in these cases, microbial toxins, particularly gram-negative bacterial endotoxin (lipopolysaccharide, LPS), and endogenous cytokine production have been implicated as initiators and mediators. Although activation of the immune system during microbial invasion is generally protective, septic shock develops in a significant number of patients as a consequence of a poorly regulated immune response to the offending organism. Sepsis can be presented with a spectrum of severity. Septic shock represents the most severe form of host response to infection. The aim of this monograph is to summarise the currently available data regarding epidemiology, pathogenesis, and optimal management of septic shock, with a particular emphasis on the role of source control in sepsis. Emerging therapies for septic shock are also discussed.
£126.74
Nova Science Publishers Inc Progress in Virus Research
Book SynopsisThe first part of the book deals with several aspects of different viruses : viral structure, function, replication and interplay between the virus and the host. Six viruses are used as examples, four RNA viruses (HTLV-I, HIV-1, MMTV and coxsackievirus B4) and two DNA viruses (EBV and KSHV). The second part of the book is devoted to the use of the knowledge on viruses to practical applications and also to the characterisation of HIV inhibitors. Reviewing the results of research on different viruses is important since, although viruses possess vast degrees of complexity, they also share similar features. In addition, viruses are more and more used as models to solve molecular biology problems.
£173.24
Nova Science Publishers Inc New Developments in Epstein-Barr Virus Research
Book SynopsisEpstein-Barr virus, frequently referred to as EBV, is a member of the herpes virus family and one of the most common human viruses. The virus occurs world-wide, and most people become infected with EBV sometime during their lives. In the United States, as many as 95% of adults between 35 and 40 years of age have been infected. Infants become susceptible to EBV as soon as maternal antibody protection (present at birth) disappears. Many children become infected with EBV, and these infections usually cause no symptoms or are indistinguishable from the other mild, brief illnesses of childhood. In the United States and in other developed countries, many persons are not infected with EBV in their childhood years. When infection with EBV occurs during adolescence or young adulthood, it causes infectious mononucleosis 35% to 50% of the time. EBV also establishes a lifelong dormant infection in some cells of the body''s immune system. A late event in a very few carriers of this virus is the emergence of Burkitt''s lymphoma and nasopharyngeal carcinoma. This new book presents leading research from around the world in this field.
£173.24
Nova Science Publishers Inc Focus on Signal Transduction Research
Book SynopsisSignal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms.
£176.24
Nova Science Publishers Inc Measles Virus Nucleoprotein
Book SynopsisMeasles virus possesses a non segmented, single stranded, negative sense RNA genome that is encapsidated by the nucleoprotein to form a helical nucleocapsid. This ribonucleoproteic complex is the substrate for both transcription and replication. The RNAdependent RNA polymerase binds to the nucleocapsid template via its co-factor, the phosphoprotein. This book focuses on the main structural information available on the nucleoprotein, showing that it consists of a structured core (NCORE) and of an intrinsically disordered C-terminal domain (NTAIL). The functional implications of the disordered nature of NTAIL are discussed in light of the ability of disordered regions to establish interactions with multiple partners, thus leading to multiple biological effects. Indeed, beyond the phosphoprotein, NTAIL also interacts with cellular partners, including the major heat shock protein, hsp72, the interferon regulator factor 3, IRF3, and a yet unidentified cellular receptor referred to as NR. This book consists of two chapters devoted to the general functions of the nucleoprotein in transcription and replication and to a detailed overview of its structural properties, and of three chapters focused on the functional relevance of the interaction between NTAIL and its various intracellular and extracellular partners.
£73.49
Bent Tree Press Fundamentals of Microbiology for Allied Health
Book Synopsis
£39.85
Nova Science Publishers Inc Hepatitis B Virus Research Focus
Book SynopsisHepatitis B virus (HBV), discovered in 1966, infects more than 350 million people in the world. The infection of HBV is a leading cause of chronic carriage of the virus and progressive liver diseases, such as hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC). HBV consists of a circular, partially double-stranded DNA molecule of 3.2 kb in length, which contains four overlapping reading frames that code for surface proteins (HBsAg), core proteins (HBcAg/HBeAg), the viral polymerase, and the transcriptional transactivator X protein. Chronic hepatitis appears to be due to a suboptimal cellular immune response that destroys some of the infected hepatocytes and does not purge the virus from the remaining infected hepatocytes, thereby permitting the persisting virus to trigger a chronic indolent necroinflammatory liver disease that sets the stage for development of HCC. However, the mechanisms responsible for malignant transformation in chronic HBV infection are not well defined, and both viral and host factors have been implicated in the process. All cases of HCC occur after many years of chronic hepatitis which could, theoretically, provide the mitogenic and mutagenic environment to precipitate random genetic and chromosomal damage, and lead to the development of HCC. Hepatitis B virus X protein (HBx), an important transforming inducer, plays a crucial role in HCC development. HBx has the capability to influence a variety of signal transduction pathways within the cells. Monitoring of the HBV genotypes and antibody to Hepatitis B x antigen (anti-HBx) are significant for predicting early diagnosis of liver cirrhosis and HCC. HBV and Hepatitis C virus or HIV coinfections can accelerate the course of chronic liver disease and facilitate progression to cirrhosis and HCC. As for therapy of liver diseases, five drugs are now FDA-approved for the treatment of HBV, including interferon (IFN), lamivudine, adefovir, entecavir, and peginterferon alfa-2a. Moreover, the prevention for HBV infection is very important. It is likely that the most important outcome of the research on HBV has been the invention, development, and application of the vaccine against HBV. However, at present most investigators focus on basic research rather than practical applications. The HBV research should be focused on animal models and clinical practice. The technology update in HBV research and the multisubject combination may be attached importance to next a few decades. Some molecular approaches, such as antisense, oligonucleotides, ribozymes, RNA interference targeting HBV mRNA, are available in antiviral therapies.
£38.24
Nova Science Publishers Inc Genomic Diversity of Bacillus-Related Species
Book SynopsisA great number of aerobic endospore-forming Gram-positive Bacillus species have been isolated on a number of occasions from a variety of terrestrial and deep-sea environments, including the Mariana Trench which has a depth of 10,897 m. Some of these Bacullus species are known to have various capabilities for adapting to extreme environments. In fact, Bacillus-related species can grow in a wide range of environments -- at pH 2-12, at temperatures between 5 and 78C, in salinity from 0 to 30% NaCl, and under pressures from 0.1 Mpa to at least 30 Mpa. The author is now exploring how these adaptive capabilities, as reflected in their genomes, were acquired and what intrinsic genomic structures are present in Bacillus-related species that have allowed them to adapt to such a wide range of environments. To answer these questions, the author initiated a genome sequencing project in early 1998 and have to present determined the entire genomic sequences of three extremophilic bacilli: alkaliphilic Bacillus halodurans, extremely halotolerant and alkaliphilic Oceanobacillus iheyensis, and thermophilic Geobacillus kaustophilus. The author provides the first comparative analysis of the extremophilic bacillar genomes with those of three other phylogenetically related mesophilic and neutrophilic bacilli, B. subtilis, B. anthracis and B. cereus, in order to highlight the commonality and diversity of the bacillar genome.
£38.24
Nova Science Publishers Inc Role of Newly Detected & Emerging Viruses in
Book SynopsisThe purpose of the book is to present up-to-date summary of the newly detected viruses and to guide clinicians and microbiologists to the relevant topics and help to make readers aware of the increasing problem of respiratory viruses. Although much is published on new respiratory viruses and its acceptance in having a daily impact in respiratory medicine, most practitioners, as well as microbiologists, neglect those pathogens or are even unaware of their existence. This may, in part, be due to the fact that most of them have only limited access to scientific journals (mainly the practitioners), whereas books are more available. An up-to-date summary is highly necessary and this book presents a short sketch for every pathogen, giving the most relevant information on each one which is followed by detailed reviews.
£73.49
Nova Science Publishers Inc Salmonella Infections: New Research
Book SynopsisInfections associated with either nontyphoid or typhoid Salmonella are a global health concern and are complicated by the increasing prevalence and levels of acquired multiple antimicrobial resistance in organisms. Salmonellosis is typically associated with foodborne illness, and transmission of resistant Salmonella through food chain, pets and humans. Prudent use of antimicrobials in human medicine and agri-food sectors is a key in minimising the emergency aspects and spread of resistant Salmonella. This book provides leading edge research in this field from around the globe.
£89.99
Nova Science Publishers Inc Human Polyomaviruses: Molecular Mechanisms for
Book Synopsis
£39.74
Nova Science Publishers Inc Viral Genomes: Diversity, Properties & Parameters
Book SynopsisThis book describes the seven different classification of viruses, including their effects on common human diseases (i.e., common cold, chicken pox) as well as the more serious diseases (AIDS, avian influenza and SARS). The nature of the human T-cell leukemia virus type 1 (HTLV-1), the first human retrovirus and the etiologic agent of neoplastic disease, adult T-cell leukaemia (ATL) is explored, as well as its effect on several inflammatory diseases. Since 1997, great concern aroused that the Asian highly pathogenic avian influenza (HPAI) H5N1 virus might turn into a pandemic strain. Thus, the enigmatic nature of the HPAI H5N1 influenza virus is also discussed. An attempt is made to identify and to characterise, qualitatively, various concrete factors that may readily become or propel critical masses. Furthermore, giant viruses, which are ancient double-stranded DNA viruses that infect a wide range of host organisms are addressed. This book also highlights current information regarding the replication, transcription, and roles of proteins of coronaviruses, viruses which are known to infect a wide range of mammalian and bird species.
£129.74
Nova Science Publishers Inc Focus on Arbovirus Infections
Book SynopsisArthropod-borne disease is a common health problem all over the world. The term "arboviral diseases" means the arthropod-borne arboviral infections. The purpose of this book is to summarise and present the topics specifically relating to the mosquito-borne disease that is unique in the tropical countries. Due to the globalisation in the present day, the change in the epidemiology of diseases from one site to the others all around the world can be expected. The summative on the common arboviral diseases can be and should be performed. This book can make them at least realise and familial with the problems. The book covers specifically the clinical aspect, scientific laboratory aspect, public health aspect as well as the social sciences relating to important arboviral infectious diseases. The common arboviral diseases are summarised, presented and discussed. Mainly the book presents summative data from the molecular to the population scales, as well as additional metanalysis for important topics. In addition, the diagnostic guideline and clinical practice guideline of the mentioned conditions will be presented. This work can be a useful reference material for the practitioners who are not familiar to the unique problems of the developing world and might face up with those problems due to the possible migration of diseases. The academic level of this book is aimed to be for the wide range from the medical student, resident, general practitioner, specialist in infectious and tropical medicine and the researchers in medical sciences. It can also be useful for the medical personnel in allied health sciences.
£73.49
Nova Science Publishers Inc Viral Gene Expression Regulation
Book SynopsisViral gene expression regulation refers to any of the processes by which cytoplasmic factors influence the differential control of gene action in viruses. The interplay of the viral genome with the host metabolic machinery involves modifications in both gene expression and regulation. Retroviruses have adapted themselves to use this machinery while maintaining the cell integrity, which is essential to preserve their survival. Consequently, there can be variable host pathogenicity associated with several diseases such as malignancies, immunodeficiencies, and neurological disorders. This book describes current research in the field, and gives a better understanding of the retroviral gene expression regulation that is essential to develop prevention and therapeutic strategies in the future.
£116.24
Nova Science Publishers Inc Water Microbiology: Types, Analyses &
Book SynopsisWater microbiology is concerned with the microorganisms that live in the water, or those that can be transported from one habitat to another by water. The improvement of pathogen detection methodology is an important issue for the efficient prevention of waterborne outbreaks in the populations world-wide. This book describes the direct detection of pathogens by molecular biologic techniques (ie: techniques based on the analysis of the nucleic acid content (DNA and RNA) of pathogens). The biosensor technology is also reviewed, focusing on their potential application for pathogen detection in water environments. Furthermore, this book presents a review on the aerobic and anaerobic processes (nutrients removal) used in the microbiological treatment of domestic wastewater and some new improvements on the bioremediation techniques. Also discussed is the biodiversity of microorganisms involved in these processes and the molecular tools that are applied to these studies. Other chapters examine both the magnitude and variety of microbes and microbial products administered in dental water, a discussion of the probable impacts of global climate change on waterborne parasitic infections, and the effects of the growth of aquaculture production systems on the quality of water and food produced.
£185.99
Nova Science Publishers Inc Pseudorabies (Aujeszky's Disease) & Its
Book Synopsis
£92.99
Nova Science Publishers Inc Dengue Virus: Detection, Diagnosis & Control
Book SynopsisDengue is an endemic viral disease affecting human population in tropical and subtropical regions around the world, predominantly in urban and semi-urban areas. Dengue fever (DF) and its more serious forms, the dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS) are becoming important public health problems. The global prevalence of dengue has grown dramatically in recent decades. An estimated 2.5 billion people in more than 100 countries are at risk of acquiring dengue viral infection with more than 50 million new infections being projected annually, between 20,000 and 25,000 deaths, mainly in children. This book aims to review the possible molecular mechanisms that attribute to the variation of Dengue virus (DENV) disease. Additionally, a description of the animal models that have been developed to study DENV pathogenesis and to test potential vaccines and therapeutics are reviewed. This book also reviews the current understanding of DENV pathogenesis and the challenges confronting vaccine and therapeutic developers. Other chapters in this book examine the responses of target cells, including dendritic cells in people infected with DENV, recent developments in the molecular diagnosis for dengue virus, the mathematical models on dengue transmission and control, and a discussion of the ways in which to prevent and control dengue outbreaks.
£185.99
Nova Science Publishers Inc Recent Trends in Biotechnology & Microbiology
Book SynopsisBiotechnology is one of the major technologies of the twenty-first century. Its wide-ranging, multi-disciplinary activities include recombinant DNA techniques, cloning and the application of microbiology to the production of goods from bread to antibiotics. In this edited book, the authors provide a complete overview of biotechnology. The fundamental principles that underpin all biotechnology are explained and a full range of examples are discussed to show how these principles are applied; from starting substrate to final product. With the use of comparative studies, this book also discusses the legal, agribusiness and public policy issues that connect intellectual property protection with advancements in agricultural biotechnology.
£107.99
Nova Science Publishers Inc Antagonistic Activity & Interaction of Probiotic
Book Synopsis
£146.24
Nova Science Publishers Inc Mushrooms: Types, Properties & Nutrition
Book Synopsis
£185.99
Nova Science Publishers Inc Encyclopedia of Virology Research: 2 Volume Set
Book SynopsisThis book presents current research in the field of virology. Topics discussed include giant viruses and their genomes; replication, transcription and translation of coronaviruses; dengue detection, diagnosis and control; dengue virus pathogenesis and animal modeling; molecular diagnostics for detecting dengue; interspecies transmission of avian influenza virus to dogs; conventional and experimental vaccines against avian influenza; molecular pathogenesis of avian influenza and the prospect of therapy using small interfering RNA and U.S. and international responses to the global spread of avian flu.
£278.99
Experiment The Whole-Body Microbiome: How to Harness
Book Synopsis
£18.99
Nova Science Publishers Inc Parvovirus B19 & Hematological Disorders in
Book SynopsisParvovirus B19 is a childhood infectious disease of global proportions. It is the leading cause of erythema infectiousum, affecting mainly young age children. This new book outlines the recent advances in understanding Parvovirus infections in children particularly associated hematological consequences. Also, it describes the associated complications by in utero infection such as hydropes fetalis and acute leukaemia. It has emerged as an occupational viral infection both to health care workers and school workers. It carries the danger of serious infection of recipients of blood and blood products transfusion.
£92.99
Nova Science Publishers Inc Rabies: Symptoms, Treatment & Prevention
Book SynopsisRabies is a viral neuroinvasive disease that causes acute encephalitis (inflammation of the brain) in warm-blooded animals. It is zoonotic (i.e., transmitted by animals), most commonly by a bite from an infected animal but occasionally by other forms of contact. Rabies is almost invariably fatal if post-exposure prophylaxis is not administered prior to the onset of severe symptoms. It is a significant killer of livestock in some countries. The rabies virus travels to the brain by following the peripheral nerves. This book gathers together important new research in the field.
£116.24
Nova Science Publishers Inc Microbiology & Molecular Biology Researcher
Book SynopsisThis book compiles biographical sketches of top professionals in the field of microbiology and molecular biology, as well as research summaries from a number of different focuses in these important fields.
£189.74
Nova Science Publishers Inc Fungi: Types, Environmental Impact & Role In
Book Synopsis
£278.99
Nova Science Publishers Inc Hepatitis C & Liver Transplantation
Book SynopsisChronic Hepatitis C virus (HCV) infection is a serious condition affecting over 180 million people world-wide. The virus infects the liver and while it is estimated that 20% of those infected clear the virus spontaneously, the virus persists in the majority of individuals leading to liver fibrosis, cirrhosis, and hepatocellular carcinoma. This book presents topical research in the study of the epidemiology, pathogenesis and treatment of Hepatitic C Virus including: genome-wide association studies regarding HCV infection; hepatic and blood dendritic cell subsets in patients with chronic HCV; bone metabolism disorders in HCV infection; Socs1 involvement in liver damage during HCV infection; asymptomatic low-level HCV persistence; and HCV infection as the leading cause of liver disease in renal transplant recipients.
£106.49
Nova Science Publishers Inc Probiotics: Sources, Types & Health Benefits
Book Synopsis
£146.24
Nova Science Publishers Inc Alimentary Microbiome: A PMEU Approach
Book Synopsis
£152.99
Nova Science Publishers Inc Salmonella: Classification, Genetics & Disease
Book Synopsis
£146.24
Nova Science Publishers Inc Hepatitis B: New Research
Book SynopsisHepatitis B virus (HBV) infection is a problem of global health importance and represents a significant cause of morbidity and mortality world-wide. HBV can be transmitted parenterally, sexually and perinatally. Despite progress on prophylaxis, diagnostic and treatment of HBV infection, it remains one of the major causes of chronic liver disease, cirrhosis or hepatocellular carcinoma. This book presents a compilation of current research including such topics as Hepatitis B and dialysis; Hepatitis B virus infection among middle school students in South Brazil; genotyping and management of chronic Hepatitis B; the risk assessment for Hepatitis B infection and its role in hepatocellular carcinoma; and silencing Hepatitis B virus replication with antiviral Pri-Mir shuttles generated from liver-specific Pol II promoters.
£106.49
Nova Science Publishers Inc Bacterial Pathogens: Virulence Mechanisms,
Book Synopsis
£126.74
Nova Science Publishers Inc Retinoic Acid: Structure, Mechanisms & Roles in
Book SynopsisRetinoic acid (RA) is a signalling molecule involved in many important pathways in every cell. When RA binds to RA receptors and activates them, cell cycle arrest, differentiation and apoptosis can occur. In this book, the authors present topical research in the study of the structure, mechanisms and roles in disease of retinoic acid. Topics discussed include retinoid signalling in mammalian inner ear development; nuclear receptors for retinoids involved in the control of expression activity of p-glycoprotein; retinoic acid signaling and immunotherapy of cancer; using retinoic acid in molecular medicine and retinol/vitamin A signalling and self-renewal of stem cells.
£106.49
Nova Science Publishers Inc Parvovirus B19 & Hematological Disorders in
Book Synopsis
£50.24
Cold Spring Harbor Laboratory Press,U.S. Tuberculosis Subject Collection from Cold Spring
Book Synopsis
£79.80
Cold Spring Harbor Laboratory Press,U.S. Human Fungal Pathogens
Book Synopsis
£79.80
Cold Spring Harbor Laboratory Press,U.S. Crispr-Cas: A Laboratory Manual
Book Synopsis
£65.55
Nova Science Publishers Inc Pseudomonas Aeruginosa: Symptoms of Infection,
Book SynopsisPseudomonas aeruginosa is a unique pathogen with a characteristic hospital epidemiology resulting in colonisation and major infectious complications. Institutions of infection control policies including guidelines on surveillance, infection control interventions and environmental decontamination are important preventive measures. In this book, the authors present current research on the symptoms of infection, antibiotic resistance and treatment of pseudomonas aeruginosa. Topics discussed include the mechanisms of antimicrobial resistance and antimicrobial treatment options; chronic pseudomonas aeruginosa infection in cystic fibrosis; and biofilm-forming ability and antimicrobial resistance of pseudomonas aeruginosa isolates of veterinary origin.
£149.99
Nova Science Publishers Inc Reassessing HIV Vaccine Design & Approaches:
Book SynopsisWhy do we not have a vaccine for HIV? What are we doing wrong? Every HIV vaccine has failed so far, and public opinion is turning pessimistic against the scientific community. HIV vaccine efforts need a major shift in strategy. They require a better understanding of the immunological mechanisms that prevent African primates from getting AIDS. None of the 40 species of African primates, including chimpanzees and gorillas, get AIDS, even though all of them carry HIV-like viruses in their bodies. Why are they "naturally vaccinated," while all of the man-made vaccines against HIV have failed miserably? This book offers intriguing new possibilities for the nature of human immunity, and the development of an effective AIDS vaccine. It is also a provocative treatise on the origin, evolution, and etiology of several forms of immune systems that is supported by a wealth of peer-reviewed scientific references. The compelling ideas presented in this study should have an important bearing on HIV vaccine development. It is a must read for anyone interested in the development of a safe AIDS vaccine, and for individuals interested in human immunity generally.
£189.74
Nova Science Publishers Inc Sex Chromosomes: New Research
Book SynopsisIn this book, the authors present new research in the study of sex chromosomes. Topics discussed in this compilation include the evolution of mammalian X chromosomes and X chromosome inactivation; the role of sex chromosomes in mammalian female fertility; the fate of the Y chromosome; the role of Y chromosome genes on tumour development risk in disgenetic gonads; deletion of amelogenin Y-locus; non-invasive prenatal diagnosis for foetal sex determination; and application of X chromosomal STR polymorphisms to individual identification.
£139.49
Nova Science Publishers Inc Microbiology & Molecular Biology Research
Book SynopsisThis new book compiles biographical sketches of top professionals in the field of microbiology and molecular biology, as well as research summaries from a number of different focuses in these important fields.
£152.99
Nova Science Publishers Inc Avian Influenza: Molecular Evolution, Outbreaks &
Book SynopsisAvian influenza or bird flu refers to "influenza caused by viruses adapted to birds". Of the greatest concern is the highly pathogenic avian influenza (HPAI). Most human contractions of the avian flu are a result of either handling dead infected birds or from contact with infected fluids. In this book, the authors discuss the molecular evolution, outbreaks and prevention/control of avian influenza. Topics include the risk assessment of highly pathogenic avian influenza virus infections through water; biosecurity measures against highly pathogenic avian influenza (HPAI) in free-range flocks and commercial poultry in developing countries; outbreak control and viral evolution of the highly pathogenic H5N1 avian influenza in Thailand; and the changes in perceptions and attitudes that were identified in a follow-up survey conducted when bird flu was not the focus on widespread media coverage in Australia.
£92.99
Nova Science Publishers Inc Glutathione: Biochemistry, Mechanisms of Action &
Book SynopsisGlutathione (γ-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol found in both prokaryotic and eukaryotic organisms. GSH has potent electron-donating capacity that renders GSH both a potent antioxidant and a conventional cofactor for enzymatic reactions. GSH participates in many cellular functions such as redox control, stress defense, drug detoxification and cell signaling including regulation of DNA and protein synthesis, gene expression, apoptosis and cell proliferation. GSH concentration in the cell is homeostatically controlled, being continually self-adjusting with respect to the balance between GSH synthesis, its recycling from GSSG and its utilization by other enzymes. Alterations in its concentration contribute to oxidative stress, which plays a key role in aging and the pathogenesis of many diseases associated with redox processes modulation. This book discusses cutting-edge developments and deals with the information gained over the last few years on the physiological, biochemical and molecular roles of the GSH and its significance in mammalian, microbial and plant cells.
£206.24
Nova Science Publishers Inc Animal Models in Cancer Research & Human Disease:
Book SynopsisThis book discusses the applications, outcomes and controversies of using animal models in cancer research and human disease. Topics include murine models of sporadic and inflammation-related colon carcinogenesis with particular focus on the AOM/DSS chemically induced colorectal cancer model; large animal models of human cardiovascular disease; developments of cell therapeutic strategies for Alzheimer''s disease using animal models; the techniques and limitations of murine models of human colorectal cancer; animal models for antineoplastic chemotherapy-induced alopecia; and development of columnar-lined oesophagus with or without goblet cells in rate duodengastroesophageal reflux models through gut regenerative cell lineage (GRCL).
£159.74
Nova Science Publishers Inc Ribosomes: Molecular Structure, Role in
Book SynopsisRibosomes are essential protein-RNA complexes that synthesize proteins according to the gene library of the cell in all living organisms. In this book, the authors present current research in the study of the molecular structure, biological functions and implications for genetic disease of ribosomes. Topics include ribosomal alterations and immune-related illness; the role of ribosomes in mediating hypoxia response and tolerance in eukaryotes; the potential biomedical use of ribosome-inactivating proteins; coarse-graining the nano-machine ribosome to elucidate its functional dynamics; and structural aspects of ribosomal ligands interactions providing the work of the human translational machinery.
£159.74
Nova Science Publishers Inc Applications of Microbial Genes in Enzyme
Book SynopsisEnzymes are necessary for nearly all of life''s chemical reactions. With the advance of biotechnology, increasing numbers of enzymes are identified and over-produced prior to application in various industries that encompass medicine, agro-industry, commodity products sectors, and biofuel biotechnologies. Many enzymes currently are derived from recombinant micro-organisms. Enzyme manufacturers take advantage of new genetic techniques to develop and manufacture enzymes with improved properties. Such enzymes often originate from micro-organisms that cannot be readily cultured under laboratory or industrial conditions. By judicious selection of host micro-organisms, recombinant production strains can be constructed to allow efficient production of enzymes that are substantially free of undesirable enzymes or other microbial metabolites. The developments in molecular genetics and cell biology in the last four decades have reshaped enzyme production. This book provides comprehensive material on applications of important microbes and their gene functions in enzyme technology for audiences across many disciplines.
£245.99
Nova Science Publishers Inc Swine Flu: Signs / Symptoms, Preventive Methods &
Book SynopsisSwine-origin influenza A (H1N1), better known as swine flu, was declared by the World Health Organization as a global pandemic in June 2009. The highly contagious influenza A H1N1 virus can cause either a mild influenza-like infection that is similar to seasonal influenza, or less frequently, a rapidly progressing community-acquired pneumonic illness that can cause acute respiratory failure and even death. This book addresses the signs/symptoms, epidemiology, preventive methods and treatment options for swine flu.
£80.24
