Medical microbiology and virology Books
National Geographic Society The Psychobiotic Revolution
Book Synopsis'A friendly, interesting, and up-to-date read on the science of the microbiome and the brain' - Psychology Today 'Compelling, engaging, and informative, this book teaches us why microbes may affect all of our decisions' - Jack Gilbert Ph.D., co-author of Dirt Is Good MEET YOUR MICROBES Written by the leading researchers in the field, this information-rich guide to improving your mood explains how gut health drives psychological well-being, and how depression and anxiety can be relieved by adjusting your intestinal bacteria. This groundbreaking book explains the revolutionary new science of psychobiotics and the discovery that your brain health and state of mind are intimately connected to your microbiome, that four-pound population of microbes living inside your intestines. Leading medical researchers John F. Cryan and Ted Dinan, working with veteran journalist Scott C. Anderson, explain how common mental health problTrade Review"More questions about gut, human health and disease? Try [The Psychobiotic Revolution]" –Psychology Today"This is an accessible guide for a lay audience on science that could radically alter the understanding of anxiety and depression, along with a host of other conditions." –Publishers Weekly “…I recommend reading The Psychobiotic Revolution by Scott C. Anderson.” –Forbes.com“Although decidedly aimed at the lay reader, the tone throughout is very humorous; I found myself swiftly turning pages, excitedly anticipating the next witty joke. Overall, this is a great book that encourages you to 'take charge of your gut to optimize your mind and your mood'. This is a book that you would reluctantly lend to friends, in the fear that they might not return it.” –Lancet "The hope is that it may one day be possible to diagnose some brain diseases and mental health problems by analysing gut bacteria, and to treat them – or at least augment the effects of drug treatments – with specific bacteria. Cryan and his colleague Ted Dinan call these mood-altering germs “psychobiotics”, and have co-written a book with the American science writer Scott C Anderson called The Psychobiotic Revolution." —The Guardian"The Psychobiotic Revolution could change how you think." —sultanabun.com"The authors of The Psychobiotic Revolution present clear research that we are indeed what we eat and that our lives would be much more enjoyable if we could balance our gut health in order to balance the rest of us." —Peppermint PhD. blog“This book is written for a lay person. It does a very good job of explaining some difficult concepts in a way that will be easily understood by people who don’t have any biology background without dumbing the subject matter down so much that people with more knowledge would cringe as they read it. That’s a fine line to walk.” –Spirit blog“Many of my burning questions were answered in a simple and succinct way that makes the battle to improve our health and diet much more feasible.” –Jathan & Heather blog“Packed with the latest scientific research, [the book] informs and fascinates” –Literary Quicksand blog“The authors have combined all the most significant information and then gleaned out the important issues that the reader needs to know in an extremely easy to read book, which becomes a real page-turner. This short book certainly relates to “You are what you Eat!” –Patricia’s Wisdom blog“This authoritative yet engaging book provides up-to-the minute research and practical advice on the gut-brain axis, perhaps the most exciting area of science today. Written by some of the leaders in the field, it gives terrific insight into what is going on in the gut, how to change it to improve mood, and the largely unappreciated links between mental health and the many other diseases now linked to the gut microbiome.”—Rob Knight, Director of the Center for Microbiome Innovation, University of California at San Diego, author of Follow Your Gut and coauthor of Dirt is Good“Anderson, Cryan and Dinan have infused life into cutting edge research that is often still mired in the scientific language…. The authors take on a near impossible task, to translate 150 years of research into the infinite complexity of human behavior and make it digestible. Compelling, engaging and informative, this book teaches us why microbes may affect all of our decisions…. This is brain food!”
£12.34
McGraw-Hill Education ISE Prescotts Principles of Microbiology
Book SynopsisPrescott''s Principles of Microbiology provides a balanced, comprehensive introduction to all major areas of microbiology. Because of this balance, Prescott''s Principles of Microbiology is appropriate for microbiology majors and mixed majors courses. The authors have focused on readability, artwork, and the integration of several key themes, including evolution, ecology and diversity, throughout the text, making an already superior text even better.Table of ContentsPart One Introduction to Microbiology1 The Evolution of Microorganisms and Microbiology2 Microscopy3 Bacterial and Archaeal Cell Structure4 Eukaryotic Cell Structure5 Bacterial and Archaeal GrowthPart Two Microbial Metabolism6 Introduction to Metabolism7 Catabolism: Energy Release and Conservation8 Anabolism: The Use of Energy in BiosynthesisPart Three Microbial Molecular Biology and Genetics9 Genome Replication10 Gene Expression11 Regulation of Cellular Processes12 Mechanisms of Genetic VariationPart Four The Diversity of the Microbial World13 Gram-Positive Bacteria14 Proteobacteria15 Nonproteobacterial Gram-Negative Bacteria16 Archaea17 Eukaryotic Microbes18 Viruses and Other Acellular Infectious Agents Part Six Host Defense and Pathogenicity22 Innate Host Resistance23 Adaptive Immunity24 The Human Microbiome and Host Interactions25 Infection and PathogenicityPart Seven Applied Microbiology26 Epidemiology and Public Health Microbiology27 Control of Microorganisms in the Environment28 Antimicrobial Chemotherapy29 Microbiology of Food30 Industrial and Environmental MicrobiologyPart Eight Methods in Microbiology31 Microbial DNA Technologies32 Microbial Genomics33 Methods in Microbial Biology34 Clinical Microbiology and Immunology
£53.09
Clinical Press Ltd The Origin of the Virus: The hidden truths behind
Book SynopsisGround-breaking, evidence-based book asks how many lives were lost because of Chinas negligence about lab-leaked SARS-CoV-2. In a disturbing reconstruction of events by two of the most reputable scientists in the world, a new book reveals for the first time how Chinese authorities and elite Wuhan scientists knew about SARS-CoV-2s menacing biological features from the start but remain silent to this day. In The Origin of the Virus (Clinical Press) Dr Steven Quay and Prof Angus Dalgleish, working with Italian reporter Paolo Barnard, show how China engaged in lies, omissions and obfuscations to cover up the laboratory origin of the virus. Had they immediately alerted the international community and policymakers of the extremely pathogenic molecular machinery present in SARS-CoV-2's genome, very large numbers of lives may have been spared, argue Quay, Dalgleish and Barnard. The authors provide a shocking account of the extreme experiments that led to the outbreak of the worst pandemic since the 1918 Spanish influenza. They broaden the censure to explain why some American and British scientists thwarted a proper investigation of the origin of COVID-19. Despite its impeccable scientific grounding the book is both a readable and gripping account that, for the first time, allows the public to partake in what lies at the heart of the many scandals surrounding the birth of the most deadly virus in modern times.Trade ReviewThe beauty of this book lies in its totally convincing narrative in a concise and entirely readable form. As a lay person with regard to medical matters I found the introductory chapter by the man who put the project together, Paolo Barnard, both fascinating and compelling, reading like a particularly enthralling story. Then the science kicks in with some hard academic research from Professor Dalgleish examining the genome of the virus and the peculiar nature of the spike proteins put there by Gain of Function studies of concern. Although impeccable in its reasoning the matters were explained in terms that are fully understandable. Then follows a nice cheeky chapter from doctor/scientist Steven Quay at the end of the book which lays out in a wonderfully logical manner how a bookie might view the odds of either zoonosis or lab-leak as the origin of the virus causing the Covid-19 pandemic .... an analysis supported by something called Bayesian statistics. I have read other books on the same matter but in my opinion this is the best .... the rival tomes are too large, filled out by journalese or just plain wrong. Once you realise that the virus has been made in a unique way such that it can attack almost any cell in the human body you begin to understand the importance of preventative measures and also become angry that the dangerous Gain of Function studies are continuing and worried that unless they are stopped the next pandemic of a novel virus will be even worse. Anthony Lloyd, primary schoolteacher and musician in Bristol, England (Review in Caduceus)
£12.75
Wolters Kluwer Health Fields Virology: Fundamentals
Book Synopsis Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: Fundamentals, Seventh Edition, edited by Drs. Peter Howley and David M. Knipe, along with volume associate editors Drs. Lynn Enquist, Jeffrey I. Cohen, Eric O. Freed, Blossom A. Damania, and Sean P. J. Whelan, focuses on the basic principles of virology and reflects recent advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as undergraduate and graduate students interested in virology. Includes chapters on virus structures, essential viral functions, immune responses to viral infections, viral epidemiology, viral diagnostics, and viral therapies Up to date discussions of antiviral therapies and vaccine strategies Features more than 300 full-color illustrations, including key figures for use as lecture slides Provides quick, flexible access to current information both in print and in an improved eBook format Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, viral persistence and latency for HIV, and mechanisms of viral oncogenesis for HPV, KSHV and the hepatotropic viruses Newly revised Field’s Virology volumes, available in print and eBook format: • Emerging Viruses • DNA Viruses • RNA Viruses • Fundamental Virology Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
£108.00
Marion Boyars Publishers Ltd Death A New Perspective on the Phenomena of
Book Synopsis
£9.45
Bloomsbury Publishing PLC Getting to Zero: A Doctor and a Diplomat on the
Book SynopsisIn 2014, a 28-year old British doctor found himself co-running the Ebola isolation unit in Sierra Leone’s main hospital after the doctor in charge had been killed by the virus. Completely overwhelmed and wrapped in stifling protective suits, he and his team took it in turns to provide care to patients while removing dead bodies from the ward. Against all odds he battled to keep the hospital open, as the queue of sick and dying patients grew every day. Only a few miles down the road the Irish Ambassador and Head of Irish Aid worked relentlessly to rapidly scale up the international response. At a time when entire districts had been quarantined, she travelled around the country, and met with UN agencies, the President and senior ministers so as to be better placed in alerting the world to the catastrophe unfolding in front of her. In this blow-by-blow account, Walsh and Johnson expose the often shocking shortcomings of the humanitarian response to the outbreak, both locally and internationally, and call our attention to the immense courage of those who put their lives on the line every day to contain the disease. Theirs is the definitive account of the fight against an epidemic that shook the world.Trade ReviewGetting to Zero is a compelling read, full of compassion, grief, ingenuity and stories of courage and unstinting commitment of local nurses, cleaners and others who remain unsung heroes of Ebola. But it is also full of tales of denial, extraordinary lapses in leadership and awkward truths that will make uncomfortable reading for many, locally and internationally. * Guardian *Written in an honest and engaging tone, their experience behind the scenes of the outbreak is illuminating and highlights important lessons for the management of future outbreaks, and the operational errors that increased the number of lives lost in the west African outbreak of 2014–16. * Lancet *Hundreds of reports have been written on the 2014 epidemic – the most widespread Ebola outbreak since the virus was discovered – but none is nearly as insightful, compassionate or unsparing as this. * Irish Times *A brave, bold, yet humble account from the frontlines of the Ebola outbreak in Sierra Leone. This is vital reading to help us all do better next time. * David Miliband, President and CEO of the International Rescue Committee *Courage in extreme clinical danger, courage to challenge obstructive bureaucracy, courage to make tough decisions and the courage to endure. This is the courage that Sinead Walsh and Oliver Johnson displayed in Sierra Leone. Their compelling book is essential reading for all who care about global health. * Eldryd Parry, founder of the Tropical Health and Education Trust *A captivating and brutally honest account of the Ebola epidemic from two brave, committed individuals who unexpectedly found themselves at its epicentre. The authors pull no punches, and leave us asking: will these lessons be learned, or will the world once again forget and move on? * Jeremy Farrar, Director of the Wellcome Trust *This powerful book asks important questions about aid and development and offers insights that everyone working in global health should absorb – as well as being a personal and very moving account of an epidemic that killed thousands. * Lord Nigel Crisp, Co-Chair of the All Party Parliamentary Group on Global Health *Walsh and Johnson represent the best of international intervention. This book reveals the complexities and level of cooperation that made “getting to zero” possible. Offers excellent insight into those trying times. * O.B. Sisay, Director of the Situation Room at the National Ebola Response Centre, Sierra Leone *An extraordinary account from the thick of the battle against Ebola. This is history’s first draft, and a powerful example of persistent and pragmatic leadership. Mandatory reading for anyone concerned with global health in the broadest sense. * Paul Farmer, Harvard Medical School, and co-founder of Partners in Health *Takes us behind the scenes to the harrowing frontlines of the Ebola epidemic – highlighting a set of lessons that an inter-connected world would ignore at our peril. A compelling read. * Samantha Power, former US Ambassador to the UN *A detailed, up-close-and-personal perspective on the Ebola epidemic in Sierra Leone, important for all who want to understand what it is to confront a terrible health threat. * Tom Frieden, President and CEO of Resolve to Save Lives, and former Director of the Centers for Disease Control and Prevention *Johnson and Walsh provide a frank, beautifully written, and essential guide to the lessons learned from the heart of the outbreak. Their first-hand experiences in battling this terrible disease will take your breath away. A must read. * Tulip Mazumdar, Global Health Correspondent for BBC News *Table of ContentsMaps Preface 1. New Beginnings: Sierra Leone before the Outbreak of Ebola 2. A Dubious Start: Ebola in Guinea 3. Ebola Emerges in Sierra Leone 4. Kenema Explodes 5. Armageddon 6. The Long Wait for Action 7. The Response Kicks Off 8. The Response Bears Fruit 9. Getting to Zero 10. Conclusion Afterword: If We Had to Do It All Again…
£14.39
Gill Microscopic Marvels
Book SynopsisGet colouring and let yourself be inspired by the marvels of the microscopic world as you make your way through this fascinating and important book.' Professor Luke O'NeillThis distinctive colouring book explores the beauty of microscopic life, from vaccines and viruses to protozoa and algae. Go on a journey of scientific discovery as your colours illuminate a hidden world beyond the limits of our own vision.Bring to life the nucleocapsid protein of the Covid-19 virus, the overlapping frill of the delphinium peregrinum seed and the shell-like carapace of a water-flea as you discover the startling and unexpected beauty of life under the lens.Containing over 60 detailed illustrations from the natural world, including a coronavirus vaccine on the cover and inside, this book is a calming celebration of small science.
£11.39
CABI Publishing Descriptions of Medical Fungi
Book SynopsisThe 4th edition of this book provides laboratory staff and clinicians with a quick benchtop reference on the identification and antifungal susceptibility of human and animal fungal infections. It contains descriptions of all the major medical fungal pathogens, 179 species from 109 genera. This updated edition includes new and revised descriptions and he authors have reconciled current morphological descriptions and name changes with more recent genetic data. The most common fungal species are described, including members of the yeasts, mucoromycetes, conidial moulds, dimorphic pathogens, and dermatophytes. The book features:updates to taxonomy and fungal names.more than 350 colour photographs. antifungal susceptibility profiles, including for new drugs where available.methods of identification including molecular and/or MALDI-ToF mass spectroscopy.This handy reference is essential for laboratory staff and clinicians dealing with the identification and management of human and animal fungal infections, researchers in medical microbiology and mycology laboratories.
£112.32
Wolters Kluwer Health Schaechter's Mechanisms of Microbial Disease
Book SynopsisKnown for generations as the most comprehensive foundational text on medical microbiology, Schaechter's Mechanisms of Microbial Disease delivers a thorough understanding of microbial agents and the pathophysiology of microbial diseases. This trusted text is universally praised for "telling the story of a pathogen" in an engaging way, facilitating learning and recall by emphasizing unifying principles and paradigms. Content is uniquely organized by microbial class and by organ system, making it equally at home in traditional and systems-based curricula. This updated 6th Edition reflects the latest advances in the field, including significant enhancements to the coverage of serious threats to global health (including COVID-19), respiratory and childhood viruses, and sexually transmitted diseases. New illustrations and additional learning features further clarify concepts, reinforce understanding, and help users confidently prepare for board exams and beyond. Abundant full-color images clarify microbial concepts, structures, and processes in vivid detail. New Subject Review Tables broaden students’ understanding of chapter content with additional context and detail. Paradigm boxes reinforce general principles through key examples. Case Studies with problem-solving questions, questions provide insight into clinical applications of microbiology, challenge students to apply what they’ve learned to common clinical scenarios. Key Concepts keep students focused on essential information. Suggested Readings guide students to relevant field research. Bolded Terms familiarize students with new or challenging terms. New content related to the COVID-19 pandemic concerning the virology, clinical features, treatment, and prevention of coronaviruses added to several relevant chapters prepares students for the clinical challenges ahead.
£68.40
HarperCollins Publishers The Mysterious World of Microorganisms
Book SynopsisBuild your child's reading confidence at home with books at the right levelNot your average science book, this in-depth analysis of the smallest living things in our world, gives captivating insight into the wonderful world of microorganisms. Focussing on bacteria, fungi, protists and viruses, it explains some of the biggest diseases of our time as well as the processes of protecting ourselves.Pearl/Band 18 books offer fluent readers a complex, substantial text with challenging themes to facilitate sustained comprehension, bridging the gap between a reading programme and longer chapter books.Text type:Curriculum links:
£10.90
HarperCollins Publishers Inc I Contain Multitudes
Book Synopsis
£23.19
McGraw-Hill Education - Europe Killer Germs
Book SynopsisOffers a retrospective of the havoc-wreaking microbes of the past as well as an engrossing exploration of emerging threats, including a chapter on bioterrorism. This book helps readers discover what makes smallpox the most potentially devastating of all bioweapons, and how prepared we are to fight it.
£19.79
Elsevier Science Publishing Co Inc FreshCut Fruits and Vegetables
Book SynopsisTrade Review"The text brings together in a single work about conventional technologies and that can help professionals in the sector and improve the nutritional quality on fruit. It is a useful reference for researchers, professionals and students who want to understand the feasiblity and operability of these techniques to make informed choices in modern processing plants." --Industrie AlimentariTable of Contents1. Quality issues and safety concerns of fresh-cut products Quality issues, Browning, Loss of firmness, Nutrient loss, Safety concerns, microbiology 2. Sanitizers Chlorine, Quaternary ammonium compounds, Acidic compounds, Alkaline compounds, Ozone, Hydrogen peroxide 3. Antioxidants Acidulants, Reducing Agents, Chelating agents, Enzyme inhibitors, other anti-brownings 4. Texturizers Calcium, Ethylene blockers, enzyme inhibitors 5. Modified and controlled atmosphere packaging 6. Natural additives with antimicrobial and flavoring potential 7. Natural additives with anti-browning and texturizer potential 8. Fortificants 9. Probiotics 10. Edible coatings 11. Active and intelligent packaging 12. High-pressure processing 13. Microwave heating 14. Ohmic heating 15. Plasma processing 16. Hurdle technology 17. Fresh-cut plant processing design
£74.96
Pearson Education (US) Clinical Laboratory Microbiology
Book SynopsisTable of ContentsPart One: Introduction to Diagnostic Microbiology Chapter 1: Development of Diagnostic Microbiology Chapter 2: Taxonomy and Classification Chapter 3: The Bacterial Cell Chapter 4: The Host’s Encounter with Microbes Chapter 5: Safety Part Two: Routine Specimen Processing Chapter 6: Specimen Collection Chapter 7: Cultivation of Microorganisms Chapter 8: Presumptive Identification Chapter 9: Final Identification Chapter 10: Immunological Tests Chapter 11: Susceptibility Testing Chapter 12: Emerging Technologies Part Three: Special Specimen Processing Chapter 13: Acid-Fast Bacilli Cultures Chapter 14: Fungal Cultures Chapter 15: Ova and Parasites Chapter 16: Viral, Chlamydial & Rickettsial Specimens Part Four: Clinically Significant Isolates Chapter 17: Aerobic Gram Positive Cocci Chapter 18: Aerobic Gram Negative Cocci Chapter 19: Aerobic Gram Positive Rods Chapter 20: Fastidious Gram-Negative Rods Chapter 21: Enterobacteriaceae Chapter 22: Non-fermenting Gram Negative Rods Chapter 23: Vibrio, Aeromonas, Plesiomonas, Campylobacter and Helicobacter Chapter 24: Anaerobic Bacteria Chapter 25: Spirochetes Chapter 26: Mycobacterium Species Chapter 27: Miscellaneous Microorganisms Chapter 28: Mycoplasma and Ureaplasma Chapter 29: Medical Mycology Chapter 30: Parasitology Chapter 31: Intracellular Microorganisms Part Five: Analysis of Body Systems for Infectious Disease Chapter 32: Cardiovascular System Chapter 33: Respiratory System Chapter 34: Urinary System
£175.47
Penguin Putnam Inc The Good Gut
Book SynopsisThe groundbreaking science behind the surprising source of good health Stanford University’s Justin and Erica Sonnenburg are pioneers in the most exciting and potentially transformative field of human health and wellness, the study of the relationship between our bodies and the trillions of organisms representing thousands of species to which our bodies play host, the microbes we call the microbiota. The Sonnenburgs argue that the microbiota determines in no small part whether we’re sick or healthy, fit or obese, sunny or moody—and that the microbiota has always been with us, coevolving with humans and entwining its functions with ours. They show us that humans are really composite organisms with microbial and human parts. But now, because of changes to diet, antibiotic over-use, and over-sterilization, our gut microbiota is facing a “mass extinction event,” which may explain the mysterious spike in some of our most troubling modern afflicti
£15.30
Oxford University Press Primary Surgery Volume 1 NonTrauma
Book SynopsisDescribes what a doctor can do if she/he cannot refer a patient, both in emergency and for 'cold surgery'. This work includes common problems such as Caesarean section, the resection of dead gut, and the release of pus from infected bones. It describes the organization and equipment found within an operating theatre.Trade ReviewIt is clear, thorough, well cross-referenced and deals with equipment and the organisation of the theatre, as well as with procedures themselves... almost certainly the best and most comprehensive text on surgery in developing countries. * Africa Health *Table of ContentsThe background to surgery; Theatres, antiseptics, and antibiotics; The control of bleeding; Basic methods and instruments; The surgery of sepsis: draining abscesses; Pus in the pleura, the pericardium, the peritoneum, and the pelvis; Pus in the muscles, bones and joints; Pus in the hands and feet; Methods for abdominal surgery; The acute abdomen: intestinal obstruction; The stomach; The appendix; The gall-bladder, pancreas, and spleen; Hernias; The surgery of conception; The surgery of pregnancy; The medicine of pregnancy; The surgery of labour; Other obstetric problems; Gynaecology; The breast and the thyroid; Proctology; Urology; The eye; The ear, nose, and throat; The teeth and mouth; Orthopaedics; Paediatric surgery; Surgery, AIDS, and hepatitis B; The surgery of tubercolosis; The surgery of leprosy; The surgery of `tropical' diseases; Oncology; Terminal care; Miscellaneous; Appendices.
£61.75
Oxford University Press Human Virology
Book SynopsisWritten by leading authors in the field with both clinical and molecular expertise, Human Virology provides an accessible introduction to this fascinating and important field, making the text ideal for students encountering virology for the first time.Trade ReviewWithout reservation. I will be recommending this edition. I will be reaching for my copy of this book and lending it to trainees. The general principles section is short but very well-put together - impressive. Subsequent chapters are organised as per Baltimore classification of viruses - this approach gives an ease of use to students that was remarked upon by the two students that I lent the book to and was obvious to me. * Dr Conall P Mccaughey, Consultant Virologist, Regional Virus Laboratory, Kelvin Laboratories, The Royal Hospitals Trust, Belfast *The book is exceptionally well-written in consistent and clear style. The writers have thought about the readers understanding. The clinical case studies are brilliant - superbly put together aimed at contextualising and making memorable the content. Several of them will be great resources to teachers. I thoroughly enjoyed reading this book as did the two students that I lent it to. * Dr Conall P Mccaughey, Consultant Virologist, Regional Virus Laboratory, Kelvin Laboratories, The Royal Hospitals Trust, Belfast *Table of ContentsPART 1: GENERAL PRINCIPLES; PART 2: SPECIFIC VIRUSES; GROUP 1 - POSITIVE SENSE SINGLE-STRANDED RNA VIRUSES; GROUP 2 - NEGATIVE-SENSE SINGLE-STRANDED RNA VIRUSES; GROUP 3 - DOUBLE-STRANDED RNA VIRUSES; GROUP 4 - DOUBLE-STRANDED DNA VIRUSES; GROUP 5 - SINGLE-STRANDED DNA VIRUSES; GROUP 6 - SINGLE-STRANDED POSITIVE SENSE RNA WITH AN RT; GROUP 7 - CIRCULAR DOUBLE-STRANDED DNA VIRUSES WITH AN RT; PART 3: PRACTICAL ASPECTS
£55.09
Oxford University Press, USA Medical Microbiology
Medical Microbiology covers a range of key laboratory techniques used in the diagnosis of human diseases caused by microorganisms such as bacteria, viruses, parasites and fungi. The text is written specifically for biomedical science students and uses case studies throughout to highlight the clinical relevance of the techniques being described.
£50.34
Oxford University Press Cancer Virus
Book SynopsisThis is the story of the discovery of the first human cancer virus. Through intriguing accounts that include some remarkable characters and individual stories from around the globe - including the UK, Africa, USA, and China - it tells the story of the Epstein-Barr virus and the understanding of its connections to a variety of other diseases.Trade Review[A] pithy, pacy study. * Nature *It reads like a thriller ... the book is compelling and colourful, capturing the romance of scientific discovery so well that it is exciting and accessible. * Linda Geddes, New Scientist *Table of ContentsAcknowledgements ; Preface ; Introduction ; 1. Out of Africa ; 2. The Eureka moment ; 3. Convincing the Sceptics ; 4. EBV in Africa - Burkitt lymphoma ; 5. EBV in Asia - Nasopharyngeal carcinoma ; 6. New Diseases - An accident of nature; an accident of medicine ; 7. Unexpected Arrivals ; 8. Prevention and Cure ; 9. Making Sense of a Human Cancer Virus ; References ; Further Reading ; Glossary ; Index
£17.99
Penguin Books Ltd The Great Influenza
Book SynopsisTHE #1 NEW YORK TIMES BESTSELLER''Everything you need to know about one of the deadliest outbreaks in human history'' Bill Gates''Easily our fullest, richest, most panoramic history of the subject'' New York Times Book ReviewIn 1918, the world faced the deadliest pandemic in human history. What can the story of the so-called Spanish Flu teach us about the fight against present day crises, and how to prepare for future outbreaks? At the height of WWI, history''s most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease.Magisterial in its breadth of perspectivTrade Review'Everything you need to know about one of the deadliest outbreaks in human history' -- Bill Gates'Easily our fullest, richest, most panoramic history of the subject' -- New York Times Book ReviewMonumental... powerfully intelligent... not just a masterful narrative... but also an authoritative and disturbing morality tale -- Chicago Tribune'A sobering account of the 1918 flu epidemic, compelling and timely' -- Boston Globe'Majestic, spellbinding treatment of a mass killer' -- Kirkus'History brilliantly written... The Great Influenza is a masterpiece' -- Baton Rouge Advocate
£10.44
Elsevier - Health Sciences Division Murrays Basic Medical Microbiology
Book SynopsisTable of ContentsSECTION I Introduction 1 Overview of Medical Microbiology SECTION II Bacteria 2 Introduction to Bacteria 3 Aerobic Gram-Positive Cocci 4 Aerobic Gram-Positive Rods 5 Acid-Fast Bacteria 6 Aerobic Gram-Negative Cocci and Coccobacilli 7 Aerobic Fermentative Gram-Negative Rods 8 Aerobic Non-fermentative Gram-Negative Rods 9 Anaerobic Bacteria 10 Spiral Shaped Bacteria 11 Intracellular Bacteria SECTION III Viruses 12 Introduction to Viruses 13 Human Immunodeficiency Viruses 14 Human Herpes Viruses 15 Respiratory Viruses 16 Hepatitis Viruses 17 Gastrointestinal Viruses 18 Human Papilloma Virus SECTION IV Fungi 19 Introduction to Fungi 20 Cutaneous and Subcutaneous Fungi 21 Systemic Dimorphic Fungi 22 Opportunistic Fungi SECTION V Parasites 23 Introduction to Parasites 24 Protozoa 25 Nematodes 26 Trematodes 27 Cestodes 28 Arthropods SECTION VI Clinical Cases-Introduction to Infectious Diseases 29 Upper Respiratory Tract Infections 30 Lower Respiratory Tract Infections 31 Gastrointestinal Tract Infections 32 Genitourinary Tract Infections 33 Central Nervous System Infections 34 Skin and Soft Tissue Infections 35 Sepsis and Cardiovascular Infections 36 Miscellaneous Infections Index
£30.39
Elsevier Health Sciences Mims Medical Microbiology and Immunology
Book Synopsis
£56.69
WW Norton & Co Did You Just Eat That Two Scientists Explore
Book SynopsisA rollicking yet rigorous inquiry that follows the science of germs into the kitchen, restaurant and everywhere else you eat and drink.
£18.04
Taylor & Francis Ltd Tumor Antigens Recognized by T Cells and
Book SynopsisRecent progress in fundamental tumor immunology has led to immunotherapy trials in patients with solid tumors and hematological malignancies. In the past, immunotherapy approaches were primarily based on enhancement of tumor immunity with cytokines and adjuvant therapy, without knowledge of relevant tumor antigens. The discovery of tumor antigens capable of eliciting immune responses has now resulted in the development of antigen-specific immunotherapy strategies. Vaccination with defined peptide epitopes, purified proteins, cell components, and whole cells expressing defined tumor antigens provides an opportunity to measure antigen-specific immune responses in vaccinated patients, and to correlate immunity with clinical outcome.Tumor Antigens Recognized by T Cells and Antibodies provides a comprehensive overview of the molecular nature of tumor antigens that can be recognized by antibodies, helper T lymphocytes and cytotoxic T lymphocytes. Novel strategies to enhance ineffectiTable of ContentsTumor Antigens Recognized by Antibodies. Human Tumor Antigens Recognized by Antibodies (SEREX). Antibodies to Tumor Oncoproteins in Cancer Patients. Antibody and CTL Responses to the NY-ESO Antigen. Tumor Antigens Recognized by CD4+ T Cells (predominantly TH1). Melanoma Antigens Recognized by CD4+ T Cells. Mouse Models in the Recognition of Tumor Antigens. Antigens of the MAGE Family Recognized by CD4+ T Cells. Tumor antigens Recognized by CD8 T Cells. Melanoma Antigens Recognized by CD8 T Cells. Squamous Cells and Adeno Cancer Antigens Recognized by T Cells. Heat/Shock Proteins and Tumor Antigens. The Wilms Tumor Antigens as CTL Target. Ex vivo and in situ Tetramer Analysis of CTL Responses to Tumors. Altered Peptide Ligands of Tumor T Cell Epitopes: Implications for More Effective Vaccine Therapy in Human Neoplasia.
£166.25
Elsevier Health Sciences Sterilization Disinfection Control
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£35.09
John Wiley and Sons Ltd Essential Microbiology for Pharmacy and
Book SynopsisThis text is an essential study guide for undergraduates studying microbiology modules on degree courses in pharmacy and the pharmaceutical sciences.Trade Review“As a quick review for budding pharmaceutical chemists who are learning pharmaceutical microbiology, this book could be useful. It is generally well written and presents a brief outline of the topics that it seeks to cover.” (Doody’s, 21 June 2013) Table of ContentsPreface vii Part I Characteristics of microorganisms Chapter 1 The microbial world 3 Chapter 2 Handling and growing microorganisms 11 Chapter 3 Bacterial structure and function 21 Chapter 4 Mycology: the study of fungi 33 Chapter 5 Protozoa 43 Chapter 6 Viruses and viral infections 49 Chapter 7 Characteristics of other microorganisms and infectious agents 57 Part II Microorganisms and the Treatment of Infections Chapter 8 Infection and immunity 65 Chapter 9 The selection and use of antibiotics 79 Chapter 10 Antibacterial antibiotics 87 Chapter 11 Antifungal agents 95 Chapter 12 Antiviral agents 103 Chapter 13 Antibiotic resistance 117 Chapter 14 Antibiotic stewardship 127 Part III Microorganisms and the Manufacture of Medicines Chapter 15 Bioburdens: counting, detecting and identifying microorganisms 137 Chapter 16 Antiseptics, disinfectants and preservatives 149 Chapter 17 The manufacture of medicines: product contamination and preservation 161 Chapter 18 The design of sterilization processes 175 Chapter 19 Sterilization methods 183 Chapter 20 The use of microorganisms in the manufacture of medicines 197 Index 209
£31.46
John Wiley & Sons Inc Infections in Pregnancy
Book SynopsisAn infection that occurs during pregnancy presents a constellation of problems above and beyond those normally associated with the disease. Even a relatively minor infection can threaten the lives of both mother and fetus and cause serious birth defects; and many conventional treatments can produce disastrous side effects during pregnancy. Over the past half-decade, enormous strides have been made in our ability to understand, diagnose, and treat infections in pregnant women. Infections in Pregnancy, Second Edition, is expanded to cover the latest and most useful guidelines for understanding, diagnosing, and treating infections during pregnancy. This comprehensive volume contains in-depth explanations of dozens of diseases and their pathologies, from common infections, such as human papilloma virus, to new and rare diseases. It provides important information on the administration, monitoring, and side effects of new antibiotics; reviews the Centers for Disease Control and PrevTrade Review"This book brings together all of these infections and as such is a comprehensive review of the subject." --Journal of Obstetrics and Gynecology, Volume 19, Number 3, 1999Table of ContentsPartial table of contents: Microflora of the Genital Tract. Antibiotic Usage in Pregnancy. Acute Chorioamnionitis. Postpartum Endometritis. Episiotomy Infection and Dehiscence. Soft-Tissue Infection. Syphilis in Pregnancy. Sexually Transmitted Diseases: I Gonorrhea and Chlamydia. Sexually Transmitted Diseases: II Chancroid, Lymphogranuloma Venereum, Granuloma Inguinale, Molluscum Contagiosum, Pediculosis Pubis, and Scabies. Hepatitis in Pregnancy. Varicella-Zoster Infection in Pregnancy. Human Immunodeficiency Virus Infection in Pregnancy. Mumps in Pregnancy. Measles in Pregnancy. Influenza Infection in Pregnancy. Protozoan Infection in Pregnancy. Pneumonia in Pregnancy. Preconceptual Counseling. Index.
£217.76
John Wiley & Sons Inc Gastroenteritis Viruses No 238 Novartis
Book SynopsisThis important book covers the structure and molecular biology of small round structured viruses (SSRVs) such as caliciviruses and astroviruses, and the basic pathology of infection. It provides readers with the knowledge needed to make progress in the prevention and treatment of these infections.Table of ContentsIntroduction (M. Estes). Gastroenteritis Viruses: An Overview (R. Glass, et al.). Structural Studies on Gastroenteritis Viruses (B. Prasad, et al.). Early Events of Rotavirus Infection: The Search for the Receptor(s) (C. Arias, et al.). Rotavirus RNA Replication and Gene Expression (J. Patton). Pathogenesis of Rotavirus Gastroenteritis (M. Estes, et al.). Correlates of Protection Against Rotavirus Infection and Disease (P. Offit). Rotavirus Epidemiology and Surveillance (U. Desselberger, et al.). A Rotavirus Vaccine for Prevention of Severe Diarrhoea of Infants and Young Children: Development, Utilization and Withdrawal (A. Kapikian). The Molecular Biology of Human Caliciviruses (I. Clarke & P. Lambden). Molecular Epidemiology of Human Enteric Caliciviruses in The Netherlands (M. Koopmans, et al.). Molecular Biology of Astroviruses: Selected Highlights (S. Matsui, et al.). Molecular Epidemiology of Human Astroviruses (S. Monroe, et al.). Enteric Infections with Coronaviruses and Toroviruses (K. Holmes). Viruses Causing Diarrhoea in AIDS (R. Pollok). Treatment of Gestrointestinal Viruses (M. Farthing). Summing-Up (M. Estes). Index of Contributors. Subject Index.
£89.06
John Wiley & Sons Inc A Practical Guide to Clinical Bacteriology
Book SynopsisInterspersed with cartoons which are simultaneously educational and amusing, this reference examines the principles of bacteriology. It has been designed as a handbook to give medical students ready access to all types of bacteria and their treatment.Table of ContentsPartial table of contents: Classification of Bacteria. Ecology and Spread of Bacteria. Pathogenesis of Bacterial Infections. Laboratory Diagnosis of Bacterial Infections. Antimicrobial Agents. Sterilisation and Disinfection. Immunisation Against Bacterial Infections. Clinical Syndromes. The Stapylococci. Bacillus Species. Listeria. The Clostridia. Treponema Species. Borrelia Species. Legionella. Brucella Species. Franciscella, Yersinia and Pasteurella Species. Coliforms, Pseudomonads and Allied Organisms. Salmonella Species. Shigella Species. Vibrios. Helicobacter Pylori. Bacteroides Species. The Mycobacteria. The Mycoplasmas. The Chlamydiae. The Rickettsiae. Index.
£95.36
John Wiley & Sons Inc Communicable Disease
Book SynopsisCommunicable Disease Epidemiology and Control Edited by Norman Noah King''s College School of Medicine and Dentistry, London, UK, and Mary O''Mahony Public Health Laboratory Service, London, UK With the growing interest in communicable diseases and their control worldwide, largely due to new and re-emerging infections, there is a need for up-to-date information in this continually changing field. Timely and wide ranging, Communicable Disease: Epidemiology and Control addresses many of the contemporary issues and provides: * Detailed and concise examination of management issues, such as commissioning and contracting, setting up an incident room, and legal aspects * A practical approach * An examination of a wide spectrum of issues in communicable diseases, including cholera, tuberculosis, Helicobacter pylori, and sexually transmitted diseases This volume is an invaluable resource for microbiologists, epidemiologists and all professionals involved in public health.Table of ContentsEPIDEMIOLOGY. Global Trends in Communicable Disease Control (A. Cliff & P. Haggett). Recent Trends in the Epidemiology and Management of Sexually Transmitted Infections (I. Simms & A. Nicoll). The Global Resurgence of Cholera (E. Mintz, et al.). The Resurgence of Tuberculosis (J. Grange). The Epidemiology of Hantavirus Pulmonary Syndrome (R. Khabbaz & J. Childs). Consequences of Helicobacter pylori Infection (R. Feldman & D. Strachan). MANAGEMENT ISSUES. Commissioning and Contracting Issues in Communicable Disease Control (G. Duckworth & A. Cummins). Setting Up an Incident Room (E. Mitchell). Legal Aspects of Communicable Disease Control (M. Painter & J. Button). Surveillance of Infectious Disease in a Region (S. Palmer). Appendix. Index.
£227.66
John Wiley & Sons Inc The Eradication of Infectious Diseases
Book SynopsisIn 1993, an International Task Force for Disease Eradication evaluated over 80 potential candidate diseases and made recommendations. However, little has been done to develop the science of eradication systematically. This book reports the findings of a multidisciplinary workshop on the eradication of infectious diseases. It reviews the history of eradication efforts and lessons from previous campaigns and distinguishes among eradication, elimination, and control programs and extinction of an etiologic agent. It addresses a wide range of related issues, including biological and socio-political criteria for eradication, costs and benefits of eradication campaigns, opportunities for strengthening primary health care in the course of eradication efforts, and other aspects of planning and implementing eradication programs. Finally, it stresses the importance of global mechanisms for formulating and implementing such programs.Table of ContentsWhat Is Eradication? (F. Fenner, et al.). Lessons from Previous Eradication Programs (A. Hinman D. Hopkins). The Role of Mathematical Models in Eradication of Infectious Disease (G. Medley, et al.). Group Report: How Is Eradication to Be Defined and What Are the Biological Criteria? (E. Ottesen, et al.). Disease Eradication Initiatives and General Health Services: Ensuring Common Principles Lead to Mutual Benefits (R. Aylward, et al.). Economic Appraisal of Eradication Programs: The Question of Infinite Benefits ( A. Acharya C. Murray). An Economic Perspective on Programs Proposed for Eradication of Infectious Diseases (M. Gyldmark A. Alban). Group Report: What Are the Criteria for Estimating the Costs and Benefits of Disease Eradication? (R. Hall, et al.). Roles for Public and Private Sectors in Eradication Programs (C. de Quadros, et al.). Overcoming Political and Cultural Barriers to Disease Eradication (S. Foster). Advantages and Disadvantages of Concurrent Eradication Programs (S. Cochi, et al.). Designing Eradication Programs to Strengthen Primary Health Care (C. Taylor R. Waldman). Group Report: What Are the Societal and Political Criteria for Eradication? (S. Cochi, et al.). Are There Better Global Mechanisms for Formulating, Implementing, and Evaluating Eradication Programs? (I. Arita). Thoughts on Organization for Disease Eradication (W. Foege). Group Report: When and How Should Eradication Programs Be Implemented? (R. Goodman, et al.). Indexes.
£276.26
John Wiley & Sons Inc Cellular Microbiology BacteriaHost Interactions
Book SynopsisThis text is for advanced undergraduates of microbiology and medical microbiology, presenting a comprehensive introduction to late-1990s molecular biology of the interactions between bacteria and eukaryotic cells, and their relevance to human diseases.Trade Review"A splendidly written book...""...the authors have achieved their goal and the book should be useful to students and researchers in many subject areas." --Microbiology Today, November 2000Table of ContentsBACKGROUND TO CELLULAR MICROBIOLOGY. An Introduction to Cellular Microbiology. The Cellular Biology Underlying Prokaryotic-Eukaryotic Interactions. Prokaryotic and Eukaryotic Signalling Mechanisms. Molecular Techniques Defining Bacterial Virulence Mechanisms. PROKARYOTIC-EUKARYOTIC INTERACTIONS IN INFECTION. Bacterial Adhesion to Host Cells. Bacterial Invasion of Host Cells. Bacterial Protein Toxins: Agents of Disease and Probes of Eukaryotic Cell Behaviour. The Innate Immune Response and Bacterial Infections. Acquired Immunity in the Defence Against Bacteria. Future Developments in Cellular Microbiology. Index.
£125.06
Cambridge University Press Modeling Disease Transmission and Its Prevention by Disinfection
Book SynopsisPathogenic microorganisms exploit a number of different routes for transmission and this book demonstrates how the spread of disease can be prevented through the practices of disinfection and controlling microbial growth.Trade ReviewReview of the hardback: ' … well written, and each chapter is extensively referenced'. The Journal of Medical MicrobiologyTable of ContentsPreface; 1. The transmission and prevention of disease C. J. Hurst and P. A. Murphy; 2. Strategies for modeling microbial colonization of the human body in health and disease R. A. Ross and M T Lee; 3. Role of pathogen monitoring in microbial risk assessment J. B. Rose, J. T. Lisle and C. N. Haas; 4. Estimating the risk of acquiring infectious disease from ingestion of water C. J. Hurst, R. M. Clark and S. E. Regli; 5. Bacterial resistance to potable water disinfectants M. H. Stewart and B. H. Olson; 6. Preventing foodborne infectious disease C. J. Hurst; 7. Disinfection of microbial aerosols S. Clark and P. Scarpino; 8. Transmission of viral infections through animate and inanimate surfaces and infection control through chemical disinfection S. A. Sattar and V. S. Springthorpe; 9. The role of chemical disinfectants in controlling bacterial contaminants on environmental surfaces D. J. Gaber, T. M. Cusack and E. Scott; 10. Sterilization and disinfection of medical devices A. B. Margolin and V. C. Chamberlain; 11. Ultraviolet light disinfection of water and wastewater P. F. Roessler and B. F. Severin; 12. Thermal inactivation of microorganisms G. Le Jean and G. Abraham; Index.
£39.99
Cambridge University Press Human Herpesviruses Biology Therapy and
Book SynopsisThis comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, EpsteinâBarr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.Table of ContentsPart I. Introduction; Part II. Basic Virology and Viral Gene Effects on Host Cell Functions; Part II. Basic Virology and Viral Gene Effects on Host Cell Functions; Part II. Basic Virology and Viral Gene Effects on Host Cell Functions; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part III. HHV- 6a, 6b and 7 Ann Arvin and Richard Whitley; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part IV. Non-Human Primate Herpesviruses Ann Arvin, Patrick Moore and Richard Whitley; Part V. Subversion of Adaptive Immunity Richard Whitley and Ann Arvin; Part VI. Antiviral Therapy Richard Whitley; Part VII. Vaccines and Immunotherapy Ann Arvin and Koichi Yamanishi; Part VIII. Herpes as Therapeutic Agents Richard Whitley and Bernard Roizman.
£498.60
Harvard University Press Suppressing the Diseases of Animals and Man
Book SynopsisTheobald Smith (18591934) is widely considered to be America's first significant medical scientist and the world's leading comparative pathologist. This is the first book-length biography of Smith to appear in print, and is based primarily on personal papers and correspondence that have remained in the possession of his family until now.Trade ReviewThis dedication to microbiologist Smith provides a detailed account of a lifelong passion for using science to alleviate human suffering. Dolman and Wolfe meticulously investigate factors in Smith’s upbringing that led him to studying medicine… The authors recount Smith’s associations with notable scientists who led him to pursue medical studies emphasizing pathology. The list of colleagues who influenced Smith’s research reads like a who’s who of microbiology. Smith’s collaborations include other famous microbiologists who investigated infectious bacterial diseases of animal and humans. Each chapter presents Smith’s research according to the chronology of his life and concurrent developments in medicine and microbiology, and discusses his contributions to controlling tragic livestock diseases such as cattle fever, hog cholera, and swine plague. -- B. R. Shmaefsky * Choice *
£33.96
Elsevier Health Sciences Clinical Cases in Microbiology and Infectious
Book Synopsis
£37.04
F.A. Davis Company Molecular Diagnostics Fundamentals Methods and
Book SynopsisMeet the challenges of this rapidly expanding field with a solid understanding of the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to practice in today's laboratories. The third edition of this popular resource encompasses microbiology, virology, genetics, oncology, and human identification.Table of Contents I. Fundamentals of Molecular Biology: An Overview 1. Nucleic Acids and Proteins 2. Gene Expression and Epigenetics II. Common Techniques in Molecular Biology 3. Nucleic Acid Extraction Methods 4. Resolution and Detection of Nucleic Acids 5. Analysis and Characterization of Nucleic Acids and Proteins 6. Nucleic Acid Amplification 7. Chromosomal Structure and Chromosomal Mutations 8. Gene Mutations 9. DNA Sequencing III. Techniques in the Clinical Laboratory 10. DNA Polymorphisms and Human Identification 11. Detection and Identification of Microorganisms 12. Molecular Detection of Inherited Diseases 13. Molecular Oncology 14. DNA-Based Tissue Typing 15. Quality Assurance and Quality Control in the Molecular Laboratory Appendices A. Study Questions Answers B. Answers to Case Studies Glossary Index
£91.85
Rutgers University Press Frederick Novy and the Development of
Book SynopsisMedical historian, medical researcher, and clinician Powel H. Kazanjian uses Novy’s archived letters, laboratory notebooks, lecture notes, and published works to examine medical research and educational activities at the University of Michigan and other key medical schools during a formative period in modern U.S. medical science. Trade Review"The 'hero narrative' of science that honours stars such as Isaac Newton and Marie Curie often obscures the multitudes who lay the foundations – that centuries-old chain of curious minds. In this biography, physician and historian Powel Kazanjian pulls one from that multitude into the light: microbiology pioneer Frederick Novy. Kazanjian's detailed and authoritative account reveals how Novy (1864-1957) did fundamental work that shaped the field's development, and introduced basic research into medical training." * Nature *"Novy has been unduly neglected by historians to date, and Kazanjian performs an important service in correcting this gap; Frederick Novy and the Development of Bacteriology in Medicine is a well-written and timely piece that alters our understanding of the rise of biomedical teaching and research in the United States." -- Scott H. Podolsky * Harvard Medical School and author of The Antibiotic Era *"Powel Kazanjian's Frederick Novy and the Development of Bacteriology in Medicine tells a critical, insightful, and overlooked story in the history of medicine and science. It is a triumph of scholarship and narrative." -- Howard Markel * author of An Anatomy of Addiction and When Germs Travel *"The great value of Kazanjian’s work is in providing a case study of how American medicine was made scientific in the late nineteenth and early twentieth centuries." * Journal of the History of Medicine and Allied Sciences *"Kazanjian has given us a much desired account of a very significant career. His main point, that Novy’s bacteriology differed from the application-focused William Welchian science of public health, expands our knowledge of American medical bacteriology. It is well founded and important. The book expands our scope of what the history of medical bacteriology is all about." * Bulletin of the History of Medicine *Table of ContentsAcknowledgments Introduction 1 Frederick Novy and the Origins of the Michigan Hygienic Laboratory 2 What Novy Did in His Medical School Laboratory 3 Making Medical Education Scientific 4 Defining Bacteriology as a Discipline in Its Early Years 5 Significance for American Culture: Arrowsmith 6 Making a Scientific Career in Medicine Conclusion Notes Index
£41.40
Taylor & Francis Inc Microbiological Assay For Pharmaceutical Analysis
Book SynopsisA user-friendly guide for the evaluation of microbiological assays, Microbiological Assay for Pharmaceutical Analysis: A Rational Approach provides a lucid explanation of the sources of error in microbiological assay and helps analysts choose efficient assay designs that will minimize those sources of error. Beginning with a review of the theoretical basis for the quantitative aspects, the author discusses microbiological assay as a branch of pharmaceutical analysis and distinguishes it from biological assay in general. He draws attention to the microbiological aspects that may not be so obvious to the chemical analyst and to the analytical aspects that may not be so obvious to the microbiologist. The book contains detailed evaluations of assays that illustrate typical experimental designs and addresses how to present a realistic assessment of the best potency estimate from a series of assays. Although there are other valuable books available in this area, they do not address Table of ContentsMicrobiological Assay in Perspective. The Agar Diffusion Assay - Its Quantitative Basis. The Theory and Practice of Tube Assays for Growth Promoting Substances. The Theory and Practice of Tube Assays for Growth Inhibiting Substances. What Do We Want of an Assay? How Do We Attain Our Goal? General Practical Aspects of Microbiological Assays. Standard Reference Materials. Parallel Lines Assays - Some Designs and Their Evaluation. Slope Ratio Assays, Some Designs and Their Evaluation. Choice of Experimental Design. Concluding Thoughts.
£356.25
CABI Publishing Molecular Variability of Fungal Pathogens
Book SynopsisThis volume contains a series of contributions from established European researchers which consider aspects of molecular variability in fungal pathogens. Chapters are derived from a workshop held in Evian, France, in September 1997, supported by the EU Concerted Action Air 3-CT94-2448. The volume is divided into three sections. The first includes contributions which consider and review the major mechanisms involved, the second details specific studies on variability in populations of different fungal pathogens, and the third includes contributions on methods for interpreting such variability. The workshop was intended to bring together methods and understanding from a wide range of fungal pathogens, and this is reflected in the volume where individual contributions include case studies and reviews of populations of fungi pathogenic on insects and nematodes as well as plant and human pathogens. The combination of mechanisms, characterisation and interpretation across a wide range of appTable of Contents1: Contributors 2: Foreword, Ulrich Kück 3: Molecular Variability of Fungal Pathogens: Using the Rice Blast Fungus as a Case Study, N J Talbot 4: Molecular Variability in Sexually Reproducing Fungal Plant Pathogens, J M Duncan, D Cooke, P Birch and R Toth 5: Parasexuality in Fungi: Mechanisms and Significance in Wild Populations, A J M Debets 6: Molecular Variability of Viruses of Fungi, K W Buck 7: Activator-like Transposons in Beauveria Species, U Kück, S Jacobsen and F Kempken 8: Fungal Pathogenesis in Insects, J Clarkson, S Screen, A Bailey, B Cobb and K Charnley 9: Combination of Different Independent Molecular Markers to Understand the Genetic Structure of Beauveria Populations, Y Couteaudier, M Viaud and C Neuvéglise 10: Assessing Diversity in Colletotrichum and Trichodera Species Using Molecular Markers, P R Mills, S Sreenivasaprasad and S Muthumeenakshi 11: Variability in the Human Opportunistic Fungal Pathogen Aspergillus fumigatus, J P Latgé, J P Debeaupuis, J Sarfati and S Paris 12: Reproduction and Population Structure in Phytopathogenic Fungi, Y Brygoo, V Caffier, J Carlier, Jean-Vincent Fabre, D Fernandez, T Giraud, X Mourichon, C Neema, Jean-Loup Notteghem, C Pope, D Tharreau and Marc-Henri Lebrun 13: Variation in the Subtilisins of Fungal Pathogens of Insects and Nematodes, T M Butt, R Segers, S C Leal and B R Kerry 14: Metabolites Influencing Pathogenicity of Nematophagous Fungi, L V Lopez-Llorca and C Olivares-Bernabeu 15: Sources of Molecular Variability and Applications in Characterization of the Plant Pathogen Fusarium oxysporum, S L Woo and M Lorito 16: Variability of Human Pathogenic Fungi, D Sullivan and D Coleman 17: Mitochondrial DNA Differences Provide Maximum Intraspecific Polymorphism in the Entomopathogenic Fungi Verticillium lecanii and Metarhizium anisopliae and Allow Isolate Detection/Identification, M A Typas, A Mavridou and V Kouvelis 18: RAPD-PCR for the Molecular Characterization of Beauveria brongniartii Isolates Useful as Biocontrol Agents of the European Cockchafer Melolontha melolontha, O I Ozino, P Piatti and F Cravanzola 19: Molecular Evolution and Phylogenetic Implications of ITS Sequence in Plants and in Fungi, J Mugnier 20: Neural Network Approaches to Interpreting Variability, L Boddy, C W Morris, A Morgan and L Al-Haddad 21: Numerical Analysis of Molecular Variability: A Comparison of Hierarchic and Non-hierarchic Methods, P Bridge 22: Index
£122.62
Distant Mirror Bechamp or Pasteur
£24.65
Pan Macmillan AirBorne
Book SynopsisCarl Zimmer writes the Origins column for The New York Times and has frequently contributed to The Atlantic, National Geographic, Time, and Scientific American. His journalism has earned numerous awards, including ones from the American Association for the Advancement of Science and the National Academies of Science, Medicine, and Engineering. Zimmer is professor adjunct at Yale, where he teaches writing. He is the author of numerous books about science, including She Has Her Mother's Laugh, which was shortlisted for the Baillie Gifford Prize, and, most recently, Air-Borne.
£21.25
John Wiley and Sons Ltd Evolution of Virulence in Eukaryotic Microbes
Book SynopsisA unique and timely review of the emergence of eukaryotic virulence in fungi, oomycetes, and protozoa, as they affect both animals and plants Evolution of Virulence in Eukaryotic Microbes addresses new developments in defining the molecular basis of virulence in eukaryotic pathogens.Trade Review“It should be of interest to evolutionary biologists, medical microbiologists and plant pathologists at postdoctoral and faculty levels.” (Microbiology Today, 26 November 2012) Table of ContentsPREFACE ix ACKNOWLEDGMENTS xi CONTRIBUTORS xiii PART I GENERAL OVERVIEWS 1 1 Population Genetics and Parasite Diversity 3Hsiao-Han Chang, Rachel F. Daniels, and Daniel L. Hartl 2 Evolution of Meiosis, Recombination, and Sexual Reproduction in Eukaryotic Microbes 17Wenjun Li, Elizabeth Savelkoul, Joseph Heitman, and John M. Logsdon, Jr. 3 Phylogenomic Analysis 44Andrew J. Roger, Martin Kolisko, and Alastair G. B. Simpson 4 Phylogenetics and Evolution of Virulence in the Kingdom Fungi 70Monica A. Garcia-Solache and Arturo Casadevall PART II POPULATION GENETICS AND EVOLUTIONARY APPROACHES 91 5 Malaria: Host Range, Diversity, and Speciation 93Ananias A. Escalante and Francisco J. Ayala 6 From Population Genomics to Elucidated Traits in Plasmodium Falciparum 111Sarah K. Volkman, Daniel E. Neafsey, Stephen F. Schaffner, Pardis C. Sabeti, and Dyann F. Wirth 7 Selective Sweeps in Human Malaria Parasites 124Xin-zhuan Su and John C. Wootton 8 Evolution of Drug Resistance in Fungi 143Jessica A. Hill, Samantha J. Hoot, Theodore C. White, and Leah E. Cowen 9 Discovery of Extant Sexual Cycles in Human Pathogenic Fungi and Their Roles in the Generation of Diversity and Virulence 168Richard J. Bennett and Kirsten Nielsen 10 Worldwide Migrations, Host Shifts, and Reemergence of Phytophthora Infestans, the Plant Destroyer 192Jean Beagle Ristaino 11 Experimental and Natural Evolution of the Cryptococcus Neoformans and Cryptococcus Gattii Species Complex 208Alexander Idnurm and Jianping Xu 12 Population Genetics, Diversity, and Spread of Virulence in Toxoplasma Gondii 231Benjamin M. Rosenthal and James W. Ajioka PART III FORWARD AND REVERSE GENETIC SYSTEMS FOR DEFINING VIRULENCE 247 13 Genetic Crosses in Plasmodium Falciparum: Analysis of Drug Resistance 249John C. Tan and Michael T. Ferdig 14 Genetic Mapping of Virulence in Rodent Malarias 269Richard Carter and Richard Culleton 15 Genetic Mapping of Acute Virulence in Toxoplasma Gondii 285L. David Sibley and John C. Boothroyd 16 Virulence in African Trypanosomes: Genetic and Molecular Approaches 307Annette Macleod, Liam J. Morrison, and Andy Tait 17 The Evolution of Antigenic Variation in African Trypanosomes 324Andrew P. Jackson and J. David Barry 18 Antigenic Variation, Adherence, and Virulence in Malaria 338Joseph Smith and Kirk W. Deitsch 19 Invasion Ligand Diversity and Pathogenesis in Blood-Stage Malaria 362Manoj T. Duraisingh, Jeffrey D. Dvorin, and Peter R. Preiser PART IV COMPARATIVE "OMICS" APPROACHES TO DEFINING VIRULENCE 385 20 Evolution of Virulence in Oomycete Plant Pathogens 387Paul R. J. Birch, Mary E. Coates, and Jim L. Beynon 21 Evolution and Genomics of the Pathogenic Candida Species Complex 404Geraldine Butler, Michael Lorenz, and Neil A. R. Gow 22 Evolution of Entamoeba Histolytica Virulence 422Upinder Singh and Christopher D. Huston 23 Sex and Virulence in Basidiomycete Pathogens 437Guus Bakkeren, Emilia K. Kruzel, and Christina M. Hull 24 Emergence of the Chytrid Fungus Batrachochytrium Dendrobatidis and Global Amphibian Declines 461Matthew C. Fisher, Jason E. Stajich, and Rhys A. Farrer 25 Impact of Horizontal Gene Transfer on Virulence of Fungal Pathogens of Plants 473Barbara J. Howlett and Richard P. Oliver 26 Evolution of Plant Pathogenicity in Fusarium Species 485Li-Jun Ma, H. Corby Kistler, and Martijn Rep 27 Genetic, Genomic, and Molecular Approaches to Define Virulence of Aspergillus Fumigatus 501Laetitia Muszkieta, William J. Steinbach, and Jean-Paul Latge 28 Cryptosporidium: Comparative Genomics and Pathogenesis 518Satomi Kato and Jessica C. Kissinger INDEX 545
£128.66
John Wiley and Sons Ltd Viral Infections and Global Change
Book SynopsisA timely exploration of the impact of global change on the emergence, reemergence, and control of vector-borne and zoonotic viral infections From massively destructive superstorms to rapidly rising sea levels, the world media is abuzz with talk of the threats to civilization posed by global warming.Trade Review“I learnt so much from the book and enjoyed reading it. It is definitely a welcome and timely addition to the biomedical literature.” (Microbiology Today, 1 August 2014) “The healthcare professionals and scientists best equipped to prevent an actual viral apocalypse will have Viral Infections and Global Change at hand, rather than a machete. Or maybe both.” (Clinical Infectious Diseases, 25 April 2014) Table of ContentsForeword xxi Preface xxiii Contributors xxv About the Editor xxix Part I General aspects 1 1 Climate Change And Vector-Borne Viral Diseases 3 Ying Zhang, Alana Hansen, and Peng Bi 1.1 Introduction 4 1.2 Epidemiology of VVD 4 1.3 Association between climatic variables and emerging VVD 6 1.4 Invasion of nonzoonotic vvd to humans 14 1.5 Implications and recommendations for prevention and control 14 References 16 2 Impact Of Climate Change On Vector-Borne Arboviral Episystems 21 Walter J. Tabachnick and Jonathan F. Day 2.1 Introduction 22 2.2 The complex factors influencing mosquito-borne arbovirus episystems 24 2.3 West Nile virus 25 2.4 Dengue in Florida 28 2.5 Bluetongue 29 2.6 Conclusions 31 Acknowledgement 32 References 32 3 Influence Of Climate Change On Mosquito Development And Blood-Feeding Patterns 35 William E. Walton and William K. Reisen 3.1 Introduction 36 3.2 Mosquito development 37 3.3 Blood-feeding patterns 46 References 52 4 Environmental Perturbations That Influence Arboviral Host Range: Insights Into Emergence Mechanisms 57 Aaron C. Brault and William K. Reisen 4.1 Introduction 57 4.2 The changing environment 59 4.3 Deforestation and the epizootic emergence of venezuelan equine encephalitis virus 62 4.4 Rice, mosquitoes, pigs, and japanese encephalitis virus 63 4.5 Culex pipiens complex, house sparrows, urbanization, and west Nile virus 66 4.6 Urbanization, global trade, and the reemergence of chikungunya virus 70 4.7 Conclusions 71 References 71 5 The Socio-Ecology Of Viral Zoonotic Transfer 77 Jonathan D. Mayer and Sarah Paige 5.1 Introduction 78 5.2 Historical perspective 78 5.3 Human–animal interface 79 5.4 Surveillance 79 5.5 Deforestation and fragmentation 80 5.6 Urbanization 81 5.7 Examples 82 5.8 Conclusion 84 References 84 6 Human Behavior And The Epidemiology Of Viral Zoonoses 87 Satesh Bidaisee, Cheryl Cox Macpherson, and Calum N.L. Macpherson 6.1 Introduction 88 6.2 Societal changes and the epidemiology of viral zoonoses 89 6.3 Viral zoonoses and human societal values 92 6.4 Human behavior and the epidemiology of vector-borne viral zoonoses 93 6.5 Human behavior and the epidemiology of respiratory viral zoonoses 96 6.6 Human behavior and the epidemiology of waterborne viral zoonoses 98 6.7 Human behavior and the epidemiology of wildlife-associated viral zoonoses 101 6.8 The role of human behavior in the control of viral zoonoses 103 References 104 7 Global Trave l, Trade, And The Spread Of Viral Infections 111 Brian D. Gushulak and Douglas W. MacPherson 7.1 Introduction 112 7.2 Basic principles 113 7.3 An overview of population mobility 113 7.4 The dynamics of modern population mobility 114 7.5 Human population mobility and the spread of viruses 115 7.6 The biological aspects of population mobility and the spread of viruses 117 7.7 The demographic aspects of population mobility and the spread of viruses 119 7.8 Potential impact of climate change 126 7.9 Conclusion 127 References 128 8 Effects Of Land-Use Changes And Agricultural Practices On The Emergence And Reemergence Of Human Viral Diseases 133 Kimberly Fornace, Marco Liverani, Jonathan Rushton, and Richard Coker 8.1 Introduction 134 8.2 Ecological and environmental changes 136 8.3 Agricultural change 139 8.4 Demographic changes 141 8.5 Land use, disease emergence, and multifactorial causation 143 8.6 Conclusion 145 References 145 9 Animal Migration And Risk Of Spread Of Viral Infections 151 Diann J. Prosser, Jessica Nagel, and John Y. Takekawa 9.1 Introduction 152 9.2 Does animal migration increase risk of viral spread? 152 9.3 Examples of migratory animals and spread of viral disease 157 9.4 Climate change effects on animal migration and viral zoonoses 166 9.5 Shifts in timing of migration and range extents 166 9.6 Combined effects of climate change, disease, and migration 167 9.7 Conclusions and future directions 169 Acknowledgements 170 References 170 10 Illegal Animal And (Bush) Meat Trade Associated Risk Of Spread Of Viral Infections 179 Christopher Kilonzo, Thomas J. Stopka, and Bruno Chomel 10.1 Introduction 180 10.2 Search strategy and selection criteria 180 10.3 The bushmeat trade 181 10.4 Bushmeat hunting and emerging infectious diseases 181 10.5 Risk factors and modes of transmission 183 10.6 Conservation and wildlife sustainability 184 10.7 Case study: The role of the bushmeat trade in the evolution of Hiv 185 10.8 Illegal trade of domestic animals and exotic pets 186 10.9 Discussion and future directions 187 10.10 Prevention and control: From supply and demand to health education techniques 187 10.11 New technologies 188 10.12 Collaboration: Multidisciplinary advances and next steps 189 10.13 Conclusion 190 Conflicts of interest 190 References 190 11 Biological Significance Of Bats As A Natural Reservoir Of Emerging Viruses 195 Angela M. Bosco-Lauth and Richard A. Bowen 11.1 Introduction 195 11.2 Bats as exemplars of biodiversity 196 11.3 Bats are reservoir hosts for zoonotic and emerging pathogens 197 11.4 Contact rate as a driver for emergence of bat-associated zoonoses 203 11.5 Potential impact of climate change on viruses transmitted by bats 205 11.6 Conclusions 206 References 206 12 Role And Strategies Of Surveillance Networks In Handling Emerging And Reemerging Viral Infections 213 Carlos Castillo-Salgado 12.1 Introduction 214 12.2 Global trend of viral infectious agents and diseases 214 12.3 Recognized importance of public health surveillance 215 12.4 Definition and scope of public health surveillance 216 12.5 Key functions and uses of disease surveillance 217 12.6 New expansion of surveillance by the ihr-2005 218 12.7 Emergence of new global surveillance networks 218 12.8 Global influenza surveillance and who’s pandemic influenza preparedness framework 219 12.9 Early warning surveillance systems 220 12.10 Innovative approaches for surveillance 222 12.11 Electronic and web-based information platforms for information reporting, sharing, and dissemination 222 12.12 Real-time and near real-time information 223 12.13 New updated statistical methods for tracking viral and infectious disease outbreaks 223 12.14 Using proxy and compiled web-based information from different sources 225 12.15 Incorporation of public–private partnerships in surveillance activities 226 12.16 Use of volunteer sentinel physicians 226 12.17 Improving guidelines and protocols for viral surveillance 226 12.18 Incorporating health situation rooms or strategic command centers for monitoring, analysis, and response in surveillance efforts 227 12.19 Challenges of viral and public health surveillance 228 References 229 13 Predictive Modeling Of Emerging Infections 233 Anna L. Buczak, Steven M. Babin, Brian H. Feighner, Phillip T. Koshute, and Sheri H. Lewis 13.1 Introduction 233 13.2 Types of models 234 13.3 Remote sensing and its use in disease outbreak prediction 235 13.4 Approaches to modeling and their evaluation 241 13.5 Examples of prediction models 244 13.6 Conclusion 250 References 250 14 Developments And Challenges In Diagnostic Virology 255 Luisa Barzon, Laura Squarzon, Monia Pacenti, and Giorgio Palù 14.1 Introduction 256 14.2 Preparedness 258 14.3 Challenges in diagnosis of emerging viral infections 259 14.4 Approaches to the diagnosis of emerging viral infections 260 14.5 Conclusions 267 Acknowledgement 268 References 268 15 Advances In Detecting And Responding To Threats From Bioterrorism And Emerging Viral Infections 275 Stephen A. Morse and Angela Weber 15.1 Introduction 276 15.2 Emerging, reemerging, and intentionally emerging diseases 276 15.3 Bioterrorism 278 15.4 Viruses as bioweapons 279 15.5 Impact of biotechnology 282 15.6 Deterrence, recognition, and response 284 15.7 Public health surveillance 288 15.8 Conclusion 291 References 291 16 Molecular And Evolutionary Mechanisms Of Viral Emergence 297 Juan Carlos Saiz, Francisco Sobrino, Noemí Sevilla, Verónica Martín, Celia Perales, and Esteban Domingo 16.1 Introduction: Biosphere and virosphere diversities 298 16.2 Virus variation as a factor in viral emergence: a role of complexity 299 16.3 High error rates originate quasispecies swarms 300 16.4 Evolutionary mechanisms that may participate in viral disease emergence 302 16.5 Ample genetic and host range variations of fmdv: a human epidemic to be? 304 16.6 The arbovirus host alternations: high exposure to environmental modifications 307 16.7 Arenaviruses: As an emerging threat 313 16.8 Conclusion 315 Acknowledgement 316 References 316 17 Drivers Of Emergence And Sources Of Future Emerging And Reemerging Viral Infections 327 Leslie A. Reperant and Albert D.M.E. Osterhaus 17.1 Introduction 328 17.2 Prehistoric and historic unfolding of the drivers of disease emergence 329 17.3 Proximal drivers of disease emergence and sources of future emerging and reemerging viral infections 334 17.4 Further insights from the theory of island biogeography 338 References 339 18 Spillover Transmission And Emergence Of Viral Outbreaks In Humans 343 Sunit K. Singh 18.1 Introduction 343 18.2 Major anthropogenic factors responsible for spillover 344 18.3 Major viral factors playing a role in spillover 347 18.4 Intermediate hosts and species barriers in viral transmission 349 18.5 Conclusion 349 References 349 Part II Specific Infections 353 19 New, Emerging, And Reemerging Respiratory Viruses 355 Fleur M. Moesker, Pieter L.A. Fraaij, and Albert D.M.E. Osterhaus 19.1 Introduction 356 19.2 Influenza viruses 359 19.3 Human metapneumovirus 362 19.4 Human coronaviruses: SARS and non-SARS 363 19.5 Human bocavirus 366 19.6 KI and WU polyomaviruses 367 19.7 Nipah and hendra viruses 368 19.8 Conclusion 369 19.9 List of abbreviations 369 References 370 20 Emergence Of Zoonotic Orthopox Virus Infections 377 Tomoki Yoshikawa, Masayuki Saijo, and Shigeru Morikawa 20.1 Smallpox, a representative orthopoxvirus infection: The eradicated non-zoonotic orthopoxvirus 377 20.2 Zoonotic Orthopoxviruses 379 Acknowledgement 387 References 387 21 Biological Aspects Of The Interspecies Transmission Of Selected Coronavi ruses 393 Anastasia N. Vlasova and Linda J. Saif 21.1 Introduction 393 21.2 Coronavirus classification and pathogenesis 397 21.3 Natural reservoirs and emergence of new coronaviruses 399 21.4 Alpha-, beta- and gamma coronaviruses: cross-species transmission 404 21.5 Anthropogenic factors and climate influence on coronavirus diversity and outbreaks 407 21.6 Conclusion 410 References 410 22 Impac t Of Environmental And Social Factors On Ross River Virus Outbreaks 419 Craig R. Williams and David O. Harley 22.1 Introduction 420 22.2 History of mosquito-borne epidemic polyarthritis outbreaks in australia and the pacific 420 22.3 RRV transmission cycles have a variety of ecologies 421 22.4 Typical environmental determinants of RRV activity 422 22.5 Social determinants of RRV disease activity 423 22.6 A Conceptual framework for understanding the influence of environmental and social factors on RRV disease activity 423 22.7 Climate Change and RRV 427 22.8 Conclusion 427 Acknowledgement 428 References 428 23 Infection Patterns And Emergence Of O’nyong-Nyong Virus 433 Ann M. Powers 23.1 Introduction 433 23.2 History of outbreaks 434 23.3 Clinical manifestations 435 23.4 Epidemiology 435 23.5 Factors affecting emergence 437 23.6 Conclusion 440 References 441 24 Zoonotic Hepa titis E: Animal Reservoirs, Emerging Risks, And Impact Of Climate Change 445 Nicole Pavio and Jérôme Bouquet 24.1 Introduction 446 24.2 HEV biology and classification 446 24.3 Pathogenesis in humans 449 24.4 Animal Reservoirs 451 24.5 Zoonotic and Interspecies Transmission of HEV and HEV-like viruses 454 24.6 HEV in the environment 456 24.7 Climate change and impact on HEV exposure 457 24.8 Prevention 458 24.9 Conclusion 458 Acknowledgement 459 References 459 25 Impact Of Climate Change On Outbreaks Of Arenaviral Infections 467 James Christopher Clegg 25.1 Introduction 467 25.2 Natural history of arenaviruses 468 25.3 Predicted climate changes 470 25.4 Arenaviral diseases and climate change 471 References 473 26 Emerging And Reemerging Human Bunyavirus Infections And Climate Change 477 Laura J. Sutherland, Assaf Anyamba, and A. Desiree LaBeaud 26.1 Introduction 478 26.2 Bunyaviridae family 478 26.3 Climate Change and Bunyaviridae: Climatic influences on transmission cycles and subsequent risk for transmission of bunyaviruses 482 26.4 Disease spread due to growing geographic distribution of competent vectors 485 26.5 using climate as a means for outbreak prediction 486 26.6 Future problems 489 References 489 27 Emerging Trend Of Astroviruses, Enteric Adenoviruses, And Rotavi ruses In Human Viral Gastroenteritis 495 Daniel Cowley, Celeste Donato, and Carl D. Kirkwood 27.1 Introduction 496 27.2 Emerging trends in rotaviruses 497 27.3 Emerging trends in enteric adenoviruses 501 27.4 Emerging trends in astroviruses 504 28 Emerging Human Norovirus Infections 517 Melissa K. Jones, Shu Zhu, and Stephanie M. Karst 28.1 Introduction 517 28.2 Norovirus epidemiology 518 28.3 Features of norovirus outbreaks 519 28.4 Clinical features of norovirus infection 521 28.5 Host Susceptibility 522 28.6 Effect of increased size of immunocompromised population 522 28.7 Effect of globalization of the food market on norovirus spread 523 28.8 Effect of climate change 525 References 525 29 Emergence Of Novel Viruses (Toscana, Usutu) In Population And Climate Change 535 Mari Paz Sánchez-Seco Fariñas and Ana Vazquez 29.1 Introduction 536 29.2 TOSV 536 29.3 USUV 542 29.4 Conclusions 550 30 Borna Disease Virus And The Search For Human Infection 557 Kathryn M. Carbone and Juan Carlos de la Torre 30.1 Introduction 558 30.2 Long-standing controversy around bdv as a human pathogen 559 30.3 A negative is impossible to prove, but do we have enough evidence to stop looking? 560 30.4 Recent improvements in testing for evidence of bdv in human samples 562 30.4.1 Serology 562 30.4.2 Nucleic acid tests 563 30.5 The possibilities for clinical expression of human bdv infection are myriad and almost impossible to predict 563 30.6 Epidemiology: the “new” frontier of human bdv studies? 565 30.7 Where do we go from here? 566 Acknowledgement 568 References 568 31 Tick-Transmitted Viruses And Climate Change 573 Agustín Estrada-Peña, Zdenek Hubálek, and Ivo Rudolf 31.1 Introduction 574 31.2 Ticks in nature 575 31.3 Family Flaviviridae 576 31.4 Family Bunyaviridae 583 31.5 Family Reoviridae 590 31.5.1 Colorado tick fever virus 590 31.5.2 Kemerovo virus 590 31.5.3 Tribeè virus 591 31.6 Family Orthomyxoviridae 591 31.6.1 Thogoto virus 591 31.6.2 Dhori virus 592 31.7 Other tick-transmitted viruses 592 31.8 Conclusions 592 Acknowledgements 594 References 594 32 The Tick–Virus Interface 603 Kristin L. McNally and Marshall E. Bloom 32.1 Introduction 604 32.2 Viruses within the tick vector 605 32.3 Saliva-assisted transmission 609 32.4 Summary and future directions 611 Acknowledgements 612 References 612 Index 617
£132.00
John Wiley and Sons Ltd Microsporidia
Book SynopsisProvides an overview of the biology of microsporidia. This book combines background and basic information on microsporidia with descriptive methods and resources for working with the pathogen. It deals with general methodologies as well as special techniques related to these organisms.Trade Review“This book represents a massive undertaking, involved 47 contributors, is splendidly produced and illustrated, and is surely destined to be the reference on the phylum for the foreseeable future. It really opened my eyes to the enormous diversity and importance of these “newcomers” to kingdom Fungi, and I have no doubt that most mycologists will have a similar reaction.” (IMA Fungus, 1 December 2014) Table of ContentsContributors xi Preface xiii Acknowledgments xv 1. Structure of Microsporidia 1 Jiří Vávra and J. I. Ronny Larsson 2. Developmental Morphology and Life Cycles of the Microsporidia 71 Ann Cali and Peter M. Takvorian 3. Epidemiology of Microsporidia in Human Infections 135 Ronald Fayer and Monica Santin-Duran 4. Epizootiology of Microsporidiosis in Invertebrate Hosts 165 Leellen F. Solter 5. Phylogenetic Place of Microsporidia in the Tree of Eukaryotes 195 Patrick J. Keeling 6. Phylogeny of the Microsporidia 203 Charles R. Vossbrinck, Bettina A. Debrunner-Vossbrinck and Louis M. Weiss 7. Microsporidian Genome Structure and Function 221 Patrick J. Keeling, Naomi M. Fast and Nicolas Corradi 8. Sex and the Microsporidia 231 Soo Chan Lee, Joseph Heitman and Joseph E. Ironside 9. Microsporidian Biochemistry and Physiology 245 Bryony A. P. Williams, Viacheslav V. Dolgikh and Yuliya Y. Sokolova 10. The Microsporidian Polar Tube and Spore Wall 261 Louis M. Weiss, Frédéric Delbac, J. Russell Hayman, Guoqing Pan, Xiaoqun Dang and Zeyang Zhou 11. The Immunology of Microsporidiosis in Mammals 307 Elizabeth S. Didier and Imtiaz A. Khan 12. Mammalian Animal Models of Human Microsporidiosis 327 Elizabeth S. Didier 13. Microsporidia Infections in Caenorhabditis elegans and Other Nematodes 341 Malina A. Bakowski, Robert J. Luallen and Emily R. Troemel 14. The Zebrafish as a Model for Microsporidiosis 357 Justin L. Sanders and Michael L. Kent 15. Clinical Syndromes Associated with Microsporidiosis 371 Louis M. Weiss 16. Ocular Microsporidiosis 403 Savitri Sharma, Praveen K. Balne and Sujata Das 17. Laboratory Diagnosis of Microsporidia 421 Kaya Ghosh, David Schwartz and Louis M. Weiss 18. Culture and Propagation of Microsporidia 457 Robert Molestina, James J. Becnel and Louis M. Weiss 19. Microsporidia in Higher Vertebrates 469 Karen F. Snowden 20. Microsporidia in Fish 493 Michael L. Kent, Ross W. Shaw and Justin L. Sanders 21. Microsporidia in Insects 521 James J. Becnel and Theodore G. Andreadis 22. Microsporidia, Honeybees, and Colony Collapse Disorder 571 Ingemar Fries 23. Microsporidia in Aquatic Invertebrates 579 Grant D. Stentiford and Alison M. Dunn 24. The Primitive Microsporidia 605 J. I. Ronny Larsson 25. Microsporidia Biological Control Agents and Pathogens of Beneficial Insects 635 Susan Bjørnson and David Oi Appendix A. Checklist of Available Generic Names for Microsporidia with Type Species and Type Hosts 671 James J. Becnel, Peter M. Takvorian and Ann Cali Appendix B. MicrosporidiaDB: the Functional Genomic Resource for Microsporidia 687 Omar S. Harb (on behalf of the EuPathDB group) Index 695
£161.06
John Wiley and Sons Ltd Endodontic Microbiology 2e
Book SynopsisEndodontic Microbiology, Second Edition presents a comprehensive reference to the microbiology, pathogenesis, management, and healing of endodontic pathosis, emphasizing the importance of biological sciences in understanding and managing endodontic disease and its interaction with systemic health.Table of ContentsContributors ix Preface xi Preface to the First Edition xiii 1 Microbial Perspectives in the Twenty-First Century 1William Wade 2 Diagnosis, Epidemiology, and Global Impact of Endodontic Infections 11Dag Ørstavik 3 Microbiology of Dental Caries and Dentinal Tubule Infection 25Robert M. Love and Anne C.R. Tanner 4 Culture-Based Analysis of Endodontic Infections 51Gunnar Dahlén 5 Molecular Analysis of Endodontic Infections 81José F. Siqueira, Jr, and Isabela N. Rôças 6 Extraradicular Endodontic Infections 129Brenda P. F. A. Gomes and Ericka T. Pinheiro 7 Virulence of Endodontic Bacterial Pathogens 149Christine Sedgley 8 Viruses in Endodontic Pathosis 179Mohamed Sabeti 9 Fungi in Endodontic Infections 197Bilge Hakan Sen and B. Güniz Baksi 10 Severe Head and Neck Infections 231Jaime S. Brahim and Robert A. Ord 11 Endodontic Infections and Pain 251Anibal Diogenes and Ken M. Hargreaves 12 Systemic Antibiotics in Endodontic Infections 269Ashraf F. Fouad 13 Topical Antimicrobials in Endodontics 287Anil Kishen 14 Endodontic Infections in Incompletely Developed Teeth 311George T.J. Huang, Domenico Ricucci, and Louis M. Lin 15 Prognosis of Healing in Treated Teeth with Endodontic Infections 341Shimon Friedman 16 Endodontic Infections and Systemic Disease 385Ashraf F. Fouad Glossary 409 Index 413
£134.06
John Wiley & Sons Inc Understanding the Gut Microbiota
Book SynopsisThis book discusses the community of microbial species (the microbiota, microbiome), which inhabits the large bowel of humans. Written from the perspective of an academic who has been familiar with the topic for 40 years, it provides a long-term perspective of knowledge about this high profile and fast-moving topic.Table of ContentsPreface vii Acknowledgements ix 1 Introduction 1 References 4 2 Prime Facts 7 Summary 14 Explanation of Terms 15 References 16 3 A Sense of Community 19 Summary 33 Explanation of Terms 33 References 35 4 Assembling Communities 39 Summary 55 Explanation of Terms 55 References 56 5 Bowel Society 63 References 69 6 Chemostat Bowel 71 Summary 82 Explanation of Terms 82 References 83 7 Revealing Secret Lives 87 Summary 98 Explanation of terms 98 References 101 8 Remembrance of Microbes Past 105 Summary 111 References 112 9 Out of Tune: Dysbiosis 115 Summary 130 Explanation of Terms 130 References 132 10 We may be Lost, but we’re Making Good Time 139 Particularly Important Considerations 143 Running Out of Fuel? 145 The End of the Journey 146 References 146 Addendum: A Brief Summary of Technological Aspects of ]omics 149 General Features of Nucleic Acid-based Technology 149 Older Electrophoretic Methods for Screening Microbiota Compositions 150 Fluorescent Probes (FISH/FC) 151 Measuring the Abundance of Bacterial Groups by qPCR 152 Using DNA Chips to Screen Microbiota Compositions 153 Detailed Phylogenetic Analysis 154 Metagenomics: Determining the Functional Capacity of Microbiotas 155 Metatranscriptomics: Microbiota Biochemical Pathways in Action 156 Metaproteomics 157 Metabolomics 157 Summary 158 References 159 Index 163
£101.66
John Wiley & Sons Inc MALDITOF and Tandem MS for Clinical Microbiology
Book SynopsisThis book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss:Challenges of IdentifyingMycobacterium to the Species level Identification of Bacteroides and Other ClinicallyRelevant AnaerobesIdentification of Species inMixed Microbial PopulationsDetection of ResistanceMechanismsProteomics as a biomarkerdiscovery and validation platformDetermination of AntimicrobialResistance using Tandem Mass SpectrometryTable of ContentsList of Contributors xxi Preface xxix Part I MALDI-TOF Mass Spectrometry 1 1 A Paradigm Shift from Research to Front]Line Microbial Diagnostics in MALDI]TOF and LC]MS/MS: A Laboratory’s Vision and Relentless Resolve to Help Develop and Implement This New Technology amidst Formidable Obstacles 3Haroun N. Shah and Saheer E. Gharbia 2 Criteria for Development of MALDI]TOF Mass Spectral Database 39Markus Kostrzewa and Thomas Maier 3 Applications of MALDI]TOF Mass Spectrometry in Clinical Diagnostic Microbiology 55Onya Opota, Guy Prod’hom and Gilbert Greub 4 The Challenges of Identifying Mycobacterium to the Species Level using MALDI]TOF MS 93 5 Transformation of Anaerobic Microbiology since the Arrival of MALDI]TOF Mass Spectrometry 123Elisabeth Nagy, Mariann Abrok, Edith Urban, A.C.M. Veloo, Arie Jan van Winkelhoff, Itaru Dekio, Saheer E. Gharbia and Haroun N. Shah 6 Differentiation of Closely Related Organisms using MALDI]TOF MS 147Mark A. Fisher 7 Identification of Species in Mixed Microbial Populations using MALDI]TOF MS 167Pierre Mahe, Maud Arsac, Nadine Perrot, Marie]Helene Charles, Patrick Broyer, Jay Hyman, John Walsh, Sonia Chatellier, Victoria Girard, Alex van Belkum, and Jean]Baptiste Veyrieras 8 Microbial DNA Analysis by MALDI]TOF Mass Spectrometry 187 9 Impact of MALDI]TOF MS in Clinical Mycology; Progress and Barriers in Diagnostics 211Cledir R. Santos, Elaine Francisco, Mariana Mazza, Ana Carolina B. Padovan, Arnaldo Colombo and Nelson Lima 10 Development and Application of MALDI]TOF for Detection of Resistance Mechanisms 231Stefan Zimmermann and Irene Burckhardt 11 Discrimination of Burkholderia Species, Brucella Biovars, Francisella tularensis and Other Taxa at the Subspecies Level by MALDI]TOF Mass Spectrometry 249Axel Karger 12 MALDI]TOF]MS Based on Ribosomal Protein Coding in S10]spc]alpha Operons for Proteotyping 269Hiroto Tamura Part II Tandem MS/MS-Based Approaches to Microbial Characterization 311 13 Tandem Mass Spectrometry Analysis as an Approach to Delineate Genetically Related Taxa 313Raju V. Misra, Tom Gaulton, Nadia Ahmod, Min Fang, Martin Hornshaw, Jenny Ho, Saheer E. Gharbia and Haroun N. Shah 14 Mapping of the Proteogenome of Clostridium difficile Isolates of Varying Virulence 379Caroline H. Chilton, Saheer E. Gharbia, Raju V. Misra, Min Fang, Ian R. Poxton, Peter S. Borriello and Haroun N. Shah 15 Determination of Antimicrobial Resistance using Tandem MassSpectrometry 399Ajit J. Shah, Vlad Serafim, Zhen Xu, Hermine Mkrtchyan and Haroun N. Shah 16 Proteotyping: Tandem Mass Spectrometry Shotgun Proteomic Characterization and Typing of Pathogenic Microorganisms 419Roger Karlsson, Lucia Gonzales]Siles, Fredrik Boulund, Asa Lindgren, Liselott Svensson]Stadler, Anders Karlsson, Erik Kristiansson and Edward R.B. Moore 17 Proteogenomics of Pseudomonas aeruginosa in Cystic Fibrosis Infections 451Liang Yang and Song Lin Chua 18 Top]Down Proteomics in the Study of Microbial Pathogenicity 493Joseph Gault, Egor Vorontsov, Mathieu Dupre, Valeria Calvaresi, Magalie Duchateau, Diogo B. Lima, Christian Malosse and Julia Chamot]Rooke 19 Tandem Mass Spectrometry in Resolving Complex Gut Microbiota Functions 505Carolin Kolmeder, Kaarina Lahteenmaki, Pirjo Wacklin, Annika Kotovuori, Ilja Ritamo, Jaana Matto, Willem M. de Vos, and Leena Valmu 20 Proteogenomics of Non]model Microorganisms 529Jean Armengaud 21A Analysis of MALDI]TOF MS Spectra using the BioNumerics Software 539Katleen Vranckx, Katrien De Bruyne and Bruno Pot 21B Subtyping of Staphylococcus spp. Based upon MALDI]TOF MS Data Analysis 563Zhen Xu, Ali Olkun, Katleen Vranckx, Hermine V. Mkrtchyan, Ajit J. Shah, Bruno Pot, Ronald R. Cutler and Haroun N. Shah 21C Elucidating the Intra]Species Proteotypes of Pseudomonas aeruginosa from Cystic Fibrosis 579Ali Olkun, Ajit J. Shah and Haroun N. Shah References 588 Index 593
£130.10
