Medical microbiology and virology Books

Book SynopsisIn 2014, a 28-year old British doctor found himself co-running the Ebola isolation unit in Sierra Leone’s main hospital after the doctor in charge had been killed by the virus. Completely overwhelmed and wrapped in stifling protective suits, he and his team took it in turns to provide care to patients while removing dead bodies from the ward. Against all odds he battled to keep the hospital open, as the queue of sick and dying patients grew every day. Only a few miles down the road the Irish Ambassador and Head of Irish Aid worked relentlessly to rapidly scale up the international response. At a time when entire districts had been quarantined, she travelled around the country, and met with UN agencies, the President and senior ministers so as to be better placed in alerting the world to the catastrophe unfolding in front of her. In this blow-by-blow account, Walsh and Johnson expose the often shocking shortcomings of the humanitarian response to the outbreak, both locally and internationally, and call our attention to the immense courage of those who put their lives on the line every day to contain the disease. Theirs is the definitive account of the fight against an epidemic that shook the world.Trade ReviewGetting to Zero is a compelling read, full of compassion, grief, ingenuity and stories of courage and unstinting commitment of local nurses, cleaners and others who remain unsung heroes of Ebola. But it is also full of tales of denial, extraordinary lapses in leadership and awkward truths that will make uncomfortable reading for many, locally and internationally. * Guardian *Written in an honest and engaging tone, their experience behind the scenes of the outbreak is illuminating and highlights important lessons for the management of future outbreaks, and the operational errors that increased the number of lives lost in the west African outbreak of 2014–16. * Lancet *Hundreds of reports have been written on the 2014 epidemic – the most widespread Ebola outbreak since the virus was discovered – but none is nearly as insightful, compassionate or unsparing as this. * Irish Times *A brave, bold, yet humble account from the frontlines of the Ebola outbreak in Sierra Leone. This is vital reading to help us all do better next time. * David Miliband, President and CEO of the International Rescue Committee *Courage in extreme clinical danger, courage to challenge obstructive bureaucracy, courage to make tough decisions and the courage to endure. This is the courage that Sinead Walsh and Oliver Johnson displayed in Sierra Leone. Their compelling book is essential reading for all who care about global health. * Eldryd Parry, founder of the Tropical Health and Education Trust *A captivating and brutally honest account of the Ebola epidemic from two brave, committed individuals who unexpectedly found themselves at its epicentre. The authors pull no punches, and leave us asking: will these lessons be learned, or will the world once again forget and move on? * Jeremy Farrar, Director of the Wellcome Trust *This powerful book asks important questions about aid and development and offers insights that everyone working in global health should absorb – as well as being a personal and very moving account of an epidemic that killed thousands. * Lord Nigel Crisp, Co-Chair of the All Party Parliamentary Group on Global Health *Walsh and Johnson represent the best of international intervention. This book reveals the complexities and level of cooperation that made “getting to zero” possible. Offers excellent insight into those trying times. * O.B. Sisay, Director of the Situation Room at the National Ebola Response Centre, Sierra Leone *An extraordinary account from the thick of the battle against Ebola. This is history’s first draft, and a powerful example of persistent and pragmatic leadership. Mandatory reading for anyone concerned with global health in the broadest sense. * Paul Farmer, Harvard Medical School, and co-founder of Partners in Health *Takes us behind the scenes to the harrowing frontlines of the Ebola epidemic – highlighting a set of lessons that an inter-connected world would ignore at our peril. A compelling read. * Samantha Power, former US Ambassador to the UN *A detailed, up-close-and-personal perspective on the Ebola epidemic in Sierra Leone, important for all who want to understand what it is to confront a terrible health threat. * Tom Frieden, President and CEO of Resolve to Save Lives, and former Director of the Centers for Disease Control and Prevention *Johnson and Walsh provide a frank, beautifully written, and essential guide to the lessons learned from the heart of the outbreak. Their first-hand experiences in battling this terrible disease will take your breath away. A must read. * Tulip Mazumdar, Global Health Correspondent for BBC News *Table of ContentsMaps Preface 1. New Beginnings: Sierra Leone before the Outbreak of Ebola 2. A Dubious Start: Ebola in Guinea 3. Ebola Emerges in Sierra Leone 4. Kenema Explodes 5. Armageddon 6. The Long Wait for Action 7. The Response Kicks Off 8. The Response Bears Fruit 9. Getting to Zero 10. Conclusion Afterword: If We Had to Do It All Again…

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Book SynopsisThe 4th edition of this book provides laboratory staff and clinicians with a quick benchtop reference on the identification and antifungal susceptibility of human and animal fungal infections. It contains descriptions of all the major medical fungal pathogens, 179 species from 109 genera. This updated edition includes new and revised descriptions and he authors have reconciled current morphological descriptions and name changes with more recent genetic data. The most common fungal species are described, including members of the yeasts, mucoromycetes, conidial moulds, dimorphic pathogens, and dermatophytes. The book features:updates to taxonomy and fungal names.more than 350 colour photographs. antifungal susceptibility profiles, including for new drugs where available.methods of identification including molecular and/or MALDI-ToF mass spectroscopy.This handy reference is essential for laboratory staff and clinicians dealing with the identification and management of human and animal fungal infections, researchers in medical microbiology and mycology laboratories.

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Book SynopsisDoes the race for vaccine development make sense? What are the chances of success? Will the vaccine be safe? Will people accept it?? In June 2020, Corona, False Alarm? exploded into the German market, selling 200,000 copies and 75,000 e-books in the first six weeks. No other topic dominates our attention as much as coronavirus and COVID-19, the infectious disease it triggers. There’s been a global deluge of contradictory opinions, fake news, and politically controlled information. Differing views on the dangers posed by the pandemic have led to deep division and confusion, within governments, society, and even among friends and family. In Corona, False Alarm?, award-winning researchers Dr. Sucharit Bhakdi and Dr. Karina Reiss give clarity to these confusing and stressful times. They offer analysis of whether radical protective measures—including lockdown, social distancing, and mandatory masking—have been justified, and what the ramifications have been for society, the economy, and public health. Dr. Bhakdi and Dr. Reiss provide dates, facts, and background information, including: How Covid-19 compares with previous coronaviruses and the flu virus What infection numbers and the death rate really tell us The challenges around lockdown: Were the protective measures justified? Mandatory mask-wearing: Does the science support it? Vaccines: What are the chances of success? What are the risks? Corona, False Alarm? provides you with sound information and substantiated facts—and encourages you to form your own opinion on the corona crisis.

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Book SynopsisThis comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, EpsteinâBarr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.Table of ContentsPart I. Introduction; Part II. Basic Virology and Viral Gene Effects on Host Cell Functions; Part II. Basic Virology and Viral Gene Effects on Host Cell Functions; Part II. Basic Virology and Viral Gene Effects on Host Cell Functions; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part III. HHV- 6a, 6b and 7 Ann Arvin and Richard Whitley; Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology; Part IV. Non-Human Primate Herpesviruses Ann Arvin, Patrick Moore and Richard Whitley; Part V. Subversion of Adaptive Immunity Richard Whitley and Ann Arvin; Part VI. Antiviral Therapy Richard Whitley; Part VII. Vaccines and Immunotherapy Ann Arvin and Koichi Yamanishi; Part VIII. Herpes as Therapeutic Agents Richard Whitley and Bernard Roizman.

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Book SynopsisNoroviruses are responsible for approximately 90% of epidemics worldwide; in particular, non-bacterial outbreaks of gastroenteritis in humans around the world, causing approximately 200,000 deaths annually in developing countries. In addition, after the introduction of rotavirus vaccination programs, the norovirus is the most common cause of paediatric gastroenteritis, requiring medical care in the high- and middle-income countries. All of this information is indicative of norovirus prevalence worldwide, and of the necessity of efforts to develop effective tools for their control and prevention. The prevalence of noroviruses worldwide is alarming, and this information is indicative of the necessity for effective tools to aid in their control and prevention. This book presents a compilation of recent research on these aspects, providing essential and specific information to help further understand the prevalence and distribution of norovirus genotypes and strains, the potential emergence of new strains of this pathogen, as well as strategies for their prevention and treatment.

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Book SynopsisTo mitigate the spread of the rare and deadly disease Ebola, Ebola Virus Disease (EVD): Outbreaks, Control and Prevention Strategies begins with the proposition of a mathematical model with vital dynamics and two preventive measures: quarantine and isolation. Humanitarian issues in Ebola prevention and control are explored, as well as the cultural practices and social norms during outbreaks. Additionally, some innovative approaches in the humanitarian response to prevention and control are discussed. The authors expose the dilemma Ebola poses to within the healthcare system, where healthcare providers are caught between the over-arching quest for self-preservation from a highly virulent disease and the professional demand of prioritising the interests of the patients over self. In conclusion, the authors describe successfully developed drug candidates from their laboratory for the treatment Ebola using EBOV protein structure, such as VP24, VP35, VP40, nucleoprotein, and glycoprotein.

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Book SynopsisThe opening study included in West Nile Virus: Outbreaks, Control and Prevention Strategies aims to design and implement an efficient data-driven agent-based model of West Nile virus spread, considering highly-mobile humans with a high level of heterogeneous properties. The authors propose a cellular difference equation model for adoption in West Nile virus-agent-based models. Following this, the authors summarize the envelope domain III protein, its production using various host systems, and applications in the development of West Nile virus vaccines and diagnostics. Lastly, this collection reviews the impacts of West Nile virus on several bird species, and discusses the implications for the long-term survival the Yellow-billed Magpie.Table of ContentsPrefaceMulti-Species, Climate-Driven and Landscape-Based Cellular Difference Equation Model for West Nile Virus: Toward an Agent-Based Model of West Nile Virus SpreadRecombinant Envelope Domain III Protein of West Nile Virus: Recent Developments and ApplicationsImpacts of West Nile Virus on the Yellow-Billed Magpie and Other Birds in Californias Central ValleyIndex.

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Book SynopsisBacterial infections have become more difficult, and sometimes impossible, to treat due to antibiotic resistance, which occurs when bacteria develop the ability to defeat the available drugs designed to kill them. According to the Centers for Disease Control and Prevention, each year, 2 million Americans become sick with antibiotic-resistant infections, and of that, about 23,000 die. This book examines the challenges related to antibiotic resistance, the development and use of diagnostic testing to identify antibiotic resistance, the development of treatments for resistant infections, and appropriate antibiotic use.Table of ContentsPreface; Antibiotic Resistance: Additional Federal Actions Needed to Better Determine Magnitude and Reduce Impact; Combating Superbugs: U.S. Public Health Responses to Antibiotic Resistance; Index.

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Book SynopsisArthropod-borne disease is a common health problem all over the world. The term "arboviral diseases" means the arthropod-borne arboviral infections. The purpose of this book is to summarise and present the topics specifically relating to the mosquito-borne disease that is unique in the tropical countries. Due to the globalisation in the present day, the change in the epidemiology of diseases from one site to the others all around the world can be expected. The summative on the common arboviral diseases can be and should be performed. This book can make them at least realise and familial with the problems. The book covers specifically the clinical aspect, scientific laboratory aspect, public health aspect as well as the social sciences relating to important arboviral infectious diseases. The common arboviral diseases are summarised, presented and discussed. Mainly the book presents summative data from the molecular to the population scales, as well as additional metanalysis for important topics. In addition, the diagnostic guideline and clinical practice guideline of the mentioned conditions will be presented. This work can be a useful reference material for the practitioners who are not familiar to the unique problems of the developing world and might face up with those problems due to the possible migration of diseases. The academic level of this book is aimed to be for the wide range from the medical student, resident, general practitioner, specialist in infectious and tropical medicine and the researchers in medical sciences. It can also be useful for the medical personnel in allied health sciences.

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Book SynopsisParvovirus B19 is a childhood infectious disease of global proportions. It is the leading cause of erythema infectiousum, affecting mainly young age children. This new book outlines the recent advances in understanding Parvovirus infections in children particularly associated hematological consequences. Also, it describes the associated complications by in utero infection such as hydropes fetalis and acute leukaemia. It has emerged as an occupational viral infection both to health care workers and school workers. It carries the danger of serious infection of recipients of blood and blood products transfusion.

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Book SynopsisThis book compiles biographical sketches of top professionals in the field of microbiology and molecular biology, as well as research summaries from a number of different focuses in these important fields.

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Book SynopsisChronic Hepatitis C virus (HCV) infection is a serious condition affecting over 180 million people world-wide. The virus infects the liver and while it is estimated that 20% of those infected clear the virus spontaneously, the virus persists in the majority of individuals leading to liver fibrosis, cirrhosis, and hepatocellular carcinoma. This book presents topical research in the study of the epidemiology, pathogenesis and treatment of Hepatitic C Virus including: genome-wide association studies regarding HCV infection; hepatic and blood dendritic cell subsets in patients with chronic HCV; bone metabolism disorders in HCV infection; Socs1 involvement in liver damage during HCV infection; asymptomatic low-level HCV persistence; and HCV infection as the leading cause of liver disease in renal transplant recipients.

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Book SynopsisHepatitis B virus (HBV) infection is a problem of global health importance and represents a significant cause of morbidity and mortality world-wide. HBV can be transmitted parenterally, sexually and perinatally. Despite progress on prophylaxis, diagnostic and treatment of HBV infection, it remains one of the major causes of chronic liver disease, cirrhosis or hepatocellular carcinoma. This book presents a compilation of current research including such topics as Hepatitis B and dialysis; Hepatitis B virus infection among middle school students in South Brazil; genotyping and management of chronic Hepatitis B; the risk assessment for Hepatitis B infection and its role in hepatocellular carcinoma; and silencing Hepatitis B virus replication with antiviral Pri-Mir shuttles generated from liver-specific Pol II promoters.

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Book SynopsisIn this book, the authors present new research in the study of sex chromosomes. Topics discussed in this compilation include the evolution of mammalian X chromosomes and X chromosome inactivation; the role of sex chromosomes in mammalian female fertility; the fate of the Y chromosome; the role of Y chromosome genes on tumour development risk in disgenetic gonads; deletion of amelogenin Y-locus; non-invasive prenatal diagnosis for foetal sex determination; and application of X chromosomal STR polymorphisms to individual identification.

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Book SynopsisAvian influenza or bird flu refers to "influenza caused by viruses adapted to birds". Of the greatest concern is the highly pathogenic avian influenza (HPAI). Most human contractions of the avian flu are a result of either handling dead infected birds or from contact with infected fluids. In this book, the authors discuss the molecular evolution, outbreaks and prevention/control of avian influenza. Topics include the risk assessment of highly pathogenic avian influenza virus infections through water; biosecurity measures against highly pathogenic avian influenza (HPAI) in free-range flocks and commercial poultry in developing countries; outbreak control and viral evolution of the highly pathogenic H5N1 avian influenza in Thailand; and the changes in perceptions and attitudes that were identified in a follow-up survey conducted when bird flu was not the focus on widespread media coverage in Australia.

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Book SynopsisGlutathione (γ-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol found in both prokaryotic and eukaryotic organisms. GSH has potent electron-donating capacity that renders GSH both a potent antioxidant and a conventional cofactor for enzymatic reactions. GSH participates in many cellular functions such as redox control, stress defense, drug detoxification and cell signaling including regulation of DNA and protein synthesis, gene expression, apoptosis and cell proliferation. GSH concentration in the cell is homeostatically controlled, being continually self-adjusting with respect to the balance between GSH synthesis, its recycling from GSSG and its utilization by other enzymes. Alterations in its concentration contribute to oxidative stress, which plays a key role in aging and the pathogenesis of many diseases associated with redox processes modulation. This book discusses cutting-edge developments and deals with the information gained over the last few years on the physiological, biochemical and molecular roles of the GSH and its significance in mammalian, microbial and plant cells.

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Book SynopsisThis book discusses the applications, outcomes and controversies of using animal models in cancer research and human disease. Topics include murine models of sporadic and inflammation-related colon carcinogenesis with particular focus on the AOM/DSS chemically induced colorectal cancer model; large animal models of human cardiovascular disease; developments of cell therapeutic strategies for Alzheimer''s disease using animal models; the techniques and limitations of murine models of human colorectal cancer; animal models for antineoplastic chemotherapy-induced alopecia; and development of columnar-lined oesophagus with or without goblet cells in rate duodengastroesophageal reflux models through gut regenerative cell lineage (GRCL).

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Book SynopsisRibosomes are essential protein-RNA complexes that synthesize proteins according to the gene library of the cell in all living organisms. In this book, the authors present current research in the study of the molecular structure, biological functions and implications for genetic disease of ribosomes. Topics include ribosomal alterations and immune-related illness; the role of ribosomes in mediating hypoxia response and tolerance in eukaryotes; the potential biomedical use of ribosome-inactivating proteins; coarse-graining the nano-machine ribosome to elucidate its functional dynamics; and structural aspects of ribosomal ligands interactions providing the work of the human translational machinery.

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Book SynopsisEnzymes are necessary for nearly all of life''s chemical reactions. With the advance of biotechnology, increasing numbers of enzymes are identified and over-produced prior to application in various industries that encompass medicine, agro-industry, commodity products sectors, and biofuel biotechnologies. Many enzymes currently are derived from recombinant micro-organisms. Enzyme manufacturers take advantage of new genetic techniques to develop and manufacture enzymes with improved properties. Such enzymes often originate from micro-organisms that cannot be readily cultured under laboratory or industrial conditions. By judicious selection of host micro-organisms, recombinant production strains can be constructed to allow efficient production of enzymes that are substantially free of undesirable enzymes or other microbial metabolites. The developments in molecular genetics and cell biology in the last four decades have reshaped enzyme production. This book provides comprehensive material on applications of important microbes and their gene functions in enzyme technology for audiences across many disciplines.

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Book SynopsisCryopreservation is a process where cells or whole tissues are preserved by cooling to sub-zero temperatures, typically 77 K. At these cold temperatures, any biological activity, including the biochemical reactions that would cause cell death, is effectively stopped. In this book, the authors discuss the technologies, applications and risks/outcomes of cryopreservation. Topics include cryopreservation of filamentous fungi; differential scanning calorimetry as a useful tool for understanding crystallisation and slow-freezing protocols; alternatives to cryopreservation for the short and long-term storage of mammalian cells; and mathematical modelling and simulations in the cryopreservation of living cells.

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Book SynopsisIn this book, the authors discuss the ecology, biological implications and environmental impact of microcosms. Topics include using microcosms to investigate aspects of plant-bacterial interactions and bacterial evolution; multifactorial microcosm experiments to predict how plant species and assemblages respond to changes in the availability and spatio-temporal heterogeneity of resources like water, light and nutrients; development and optimisation of an aquatic laboratory microcosm for ecotoxicological risk assessment; assessment on transformation of organic pollutants in microcosms; bacterial evolution in simple microcosms; ecology and environmental side-effects of pesticides in tropical microcosms; floating dish microcosms to study the developments of biofilm communities; the role of semiosis and cohesion and sustainability inside microcosms; and soil microcosms and biogeographical research.

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Book SynopsisToxoplasmosis is one of the most important food-borne illnesses and foetal maternal inflammatory syndromes. Currently, there is no safe and effective approved therapy against foetal maternal complication or persistent chronic infection. Toxoplasma is an intracellular organism. About 1.5 billion people world-wide are predicted to have toxoplasmosis, frequently with unknown lifelong health consequences. Toxoplasma is classified as "Category B pathogen" according to the Center for Disease Control (CDC) and National Institute of Health (NIH). The organisms reside in muscles and brain in cyst forms for the lifetime of the host awaiting reactivation. This book discusses several topics which include foetal and maternal toxoplasmosis; toxoplasma gondii and suicide and homicide; toxoplasmosis in several animals including cattle, goats, swine, dogs, and kittens; and molecular diagnosis in toxoplasmosis.

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Book SynopsisThis book describes the issues of human health and healthcare from the point of view of hygiene monitoring and maintenance. Also, the perspectives on the effects of microbial cell structures, metabolism, communities and interactions on health and hygiene are included. Besides microbiological screening of patients, surfaces, air space etc. this book introduces some key bacteriological, virological and fungal risks in the clinical setting. It describes routes of contamination inside hospitals, and into our body. The means for prevention of the spreading of unwanted microbes are presented as well. Protection mechanisms of the bodily system and the balances of the human microbiome are discussed with respect to intrusions via the respiratory or digestive systems or damaged skin. The risks during operations or invasive treatments are highlighted, together with means for avoiding them. Examples of biofilm formation on the devices or on the body surfaces, latent infections, contagion mechanisms, as well as prevalent risks such as mycobacterial infections, antibiotic resistant strains, intracellular pathogens, nosocomial viruses, lowered host defences, Clostridium difficile, salmonellas, legionellas are included in the chapters of this book. Important developments such as personalized medicine, point-of-care diagnostics, arthroscopy, improved drug delivery, pre- and probiotic treatments, monitoring of the normal flora and its beneficial effects are also discussed.

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Book SynopsisThe Ebola virus is named after the Ebola River, near where the virus was discovered in 1976 in Zaire, now known as the Democratic Republic of the Congo (DRC). It is in the filovirus family, so called because of its filamentous shape. EVD is also known as Ebola haemorrhagic fever. The disease sometimes causes haemorrhage (ie: bleeding) from body openings, but this symptom is not consistent. Five strains of Ebola virus have been identified. This book discusses the essentials, response efforts, and prevention issues involved with the Ebola virus.

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Book SynopsisViral hemorrhagic fevers (VHFs) represent a collection of illnesses caused by several distinct viral families. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause life-threatening diseases. The chapters of this book discuss the consequences of the Ebola outbreak in West Africa; the most frequency imported infection worldwide (malaria); the reservoirs of selected infectious diseases (often bats and fruit bats); the clinical symptoms of viral diseases and the most widely used diagnostic methods for the correct identification of the pathogen involved; and a discussion on Japanese encephalitis (JE) as an infectious disease caused by a virus transmitted by blood-sucking arthropods.

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Book SynopsisExposure to certain types of mycotoxins, the bioactive secondary metabolites of filamentous fungi, significantly impact the animal industry as well as human health. The contamination of food with mycotoxins is a worldwide problem in animal production and direct consequences are the reducing of food intake and production. In this book, the authors increase the public awareness of the implications of certain types of mycotoxins exposure to promote the health of livestock as well as the general public; an analysis of trichothecens (TCEs), a large group of mycotoxins, and their impact on lifestock health and production are also examined, as well as the occurrence of mycotoxins in animal products such as goat milk. Different strategies implemented for the analysis of a wide spectrum of mycotoxins, as well as their advantages and disadvantages are provided by the authors. In the next few chapters, the occurrence of mycotoxins in cereals and cereal products and in particular, their toxic properties are looked at; a discussion on deoxynivalenol (DON) and related 8-ketotrichothecene mycotoxins, which are extensively distributed in cereal-based foods and feed stuffs worldwide are reviewed; potential toxigenic fungi from diverse habitats are identified with special emphasis on the methods as well as on the genetic markers employed; the importance of performing exposure assessments to Aflatoxin B and some of the most important aspects to consider in the risk assessment process, including the simultaneous presence of other mycotoxins and the challenge of choosing the most suitable method to perform exposure assessment are analyzed; and finally, a review of the occurrence of dietary mycotoxins in Africa as well as the advances in analytical methods of mycotoxin extraction and detection over the last decade is provided.

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Book SynopsisDesigned as reference material to increase knowledge of the human body. Beautiful full-colour illustrations help enhance understanding of the body or illness. Suitable for healthcare professions, patients, students, educators and parents.

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Book SynopsisText in English & French. This book gathers together all the most recent world-wide knowledge in the various fields of research into the Epstein-Barr virus (EBV), from the most fundamental subjects (virology, molecular and cellular biology and immunology) through epidemiology, pathological anatomy, clinical research and therapeutics. Featured in the book are highly original chapters dealing with malignant lymphomas in AIDS patients, detection and prevention in developing countries, formulation of an anti-EBV vaccine. This comprehensive and clearly written book is a valuable and essential tool for all researchers and clinicians.

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Book SynopsisThis meeting dealt with all the recent progresses in the diagnostic techniques for the presently most popular hepatotropic agent: hepatitis C virus. These included serological assays, amplification procedures, RNA quantitation, genotyping and serotyping: all topics covered by European specialists. Meeting of the French group for molecular study of hepatitis (called GEMHEP), Paris, November 1993.

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Book SynopsisResearchers are still identifying micro-organisms that cause new diseases in humans. A basic factor in the emergence of these diseases is the role played by animals, which act as a reservoir for certain viruses. In favourable conditions, such viruses can cross the species barrier and infect humans. The book takes a close look at two families of virus: orthomyxoviridae and paramyxoviridae, which have infected many species of vertebrates and are responsible for zoonosis. The two main parts of the book describe how the viruses operate, how they spread and the risk factors for humans. In addition to a specific and detailed study of these two micro-organisms, the book highlights the fascinating history of such diseases, their emergence, development and disappearance. They have occurred throughout human history, underscoring the role of the environment and the way it changes, often as a result of human intervention. Sponsored by the Mérieux Foundation and written by leading international specialists, this book provides first-class information about these new viruses.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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