Medical microbiology and virology Books
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG HIV und AIDS: Ein Leitfaden für Ärzte, Apotheker,
Book SynopsisDer vorliegende Leitfaden soll nicht nur über Grundlagen und HIV-assoziierte Krankheitsbilder informieren, sondern auch die Probleme der einzelnen Fachdisziplinen darstellen. Weitere Kapitel befassen sich mit der symptomorientierten Diagnosestellung und den psychosozialen Aspekten der HIV-Infektion.Table of ContentsI.Grundlagen.- I. 1 Epidemiologie.- I. 1.1 Weltweit.- I. 1.2 HIV/AIDS in Deutschland - Eckdaten und Trends, Ende 2001.- I.2 Das Virus.- I. 2.1 Aufbau.- I. 2.2 Vermehrung.- I. 2.3 Zielzellen für HIV.- I. 2.4 Übertragung.- I. 2.5 HIV-Subtypen.- I. 3 Infektionsverlauf.- I. 3.1 Klinischer Verlauf (ohne medikamentöse Therapie).- I. 3.2 Laborverlauf (ohne medikamentöse Therapie).- I.4 Immunologie (Jörg-Andres Rump).- I. 4.1 HIV und das Immunsystem.- II. Diagnostik.- II. 1 CDC-Klassifikation (1993).- II. 1.1 Die Laborkategorien 1 bis 3.- II. 1.2 Die klinischen Kategorien A bis C.- II. 2 HIV-Tests (Benedikt Weißbrich).- II. 2.1 Testberatung (Erdwine Klinker).- II. 3 Vorgehen bei diagnostizierter HIV-Infektion.- II.4 Laboruntersuchungen.- II. 4.1 Anforderungen an die Laborleistungen.- II. 4.2 Erstuntersuchung.- II. 4.3 Verlaufskontrolle und Untersuchungsfrequenz.- II. 4.4 Viruslastbestimmung (Bettina Gröschel).- III. Therapie.- III. 1 Antiretrovirale Therapie (ART).- III. 1.1 Prognose in Abhängigkeit von der Viruslast.- III. 1.2 Indikation für den Beginn der antiretroviralen Therapie.- III. 1.3 Aktuelle antiretrovirale Therapien beim unvorbehandelten Patienten.- III. 1.4 Einnahmehinweise für Medikamente zur antiretroviralen Therapie (in alphabetischer Reihenfolge).- III. 1.5 Nuldeosidale Reverse Transkriptaseinhibitoren (NRTI).- III. 1.6 Nicht-Nuleosidale Reverse Transkriptaseinhibitoren (NNRTI).- III. 1.7 Proteaseinhibitoren (PI).- III. 1.8 Kombinationsmöglichkeiten und Dosierungen von Proteaseinhibitoren (PI).- III. 1.9 Therapeutisches Drug Monitoring (TDM) (Hartwig Klinker).- III. 1.10 Neue antiretrovirale Substanzen.- III. 1.11 Übersicht zur Impfstoffentwicklung gegen die HIV-Infektion (Matthias T. Dittmar und Hans-Georg Kräusslich).- III. 1.12 Molekularbiologische und sonstige Therapieansätze.- III. 1.13 Strukturierte Therapiepausen.- III. 1.14 Immunglobuline (Martin Hartmann).- III. 1.15 HIV in Gynäkologie und Geburtshilfe (Matthias Beichert).- III. 1.16 Nadelstichverletzungen - Merkblatt (Martin Hartmann).- III. 1.17 Spezifische Nebenwirkungen (Martin Hartmann).- III. 1.17.1 Hautreaktionen unter antiretroviraler Therapie.- III. 1.17.2 Das Lipodystrophie-Syndrom (Martin Hartmann).- III. 1.17.3 Nebenwirkungen von Nukleosidanaloga in der antiretroviralen Langzeit-Therapie - mitochondriale Toxizität (Ulrich A. Walker).- III. 1.17.4 Hypersensitivitätssyndrom unter Abacavir (Thomas Stark und Ravi Walli).- III. 1.18 Therapieversagen (Thomas Stark).- III. 2 Resistenzentwicklung (Wirkverlust antiretroviraler Medikamente) (Klaus Heintz, Myriam Mendila und Ravi Wall).- III. 2.1 ANRS Algorhythmus für NRTIs.- III. 2.2 ANRS Algorhythmus für NNRTIs.- III. 2.3 ANRS Algorhythmus für PIs.- III. 3 Komplementäre Therapieformen.- IV. Häufigste Krankheitsbilder und Ihre Therapien.- IV. 1 Orale Haarleukoplakie.- IV. 2 Candida-Infektionen.- IV. 2.1 Medikamente gegen Candida-Infektionen.- IV. 3 Herpes simplex-Infektionen.- IV. 3.1 Medikamente gegen Herpes simplex-Infektionen.- IV. 4 Varizella zoster-Infektionen.- IV. 4.1 Medikamente gegen Varizella zoster-Infektionen (Herpes zoster).- IV. 5 CMV-Infektionen.- IV. 5.1 Medikamente zur Therapie von CMV-Infektionen.- IV. 6 Pneumocystis carinii-Pneumonie (PcP).- IV. 6.1 Medikamente gegen Pneumocystis carinii-Pneumonie (PcP).- IV. 7 Zerebrale Toxoplasmose.- IV. 7.1 Medikamente gegen zerebrale Toxoplasmose.- IV. 8 Tuberkulose.- IV. 8.1 Medikamente gegen Tuberkulose.- IV. 9 Atypische Mykobakteriose.- IV. 9.1 Medikamente gegen atypische Mykobakteriose.- IV. 10 Kryptosporidiosen.- IV. 10.1 Medikamente gegen Kryptosporidiosen.- IV. 11 Aspergillose.- IV. 11.1 Medikamente gegen Aspergillose.- IV. 12 Kryptokokkose.- IV. 12.1 Medikamente gegen Kryptokokkose.- IV 13 Wasting-Syndrom.- IV. 14 HIV-Enzephalopathie.- IV. 15 Kaposi-Sarkom (KS).- IV. 16 Lymphome.- IV. 17 Andere Tumoren.- V. Neue Krankheitsbilder.- V. 1 Hepatitis-Koinfektion (Hepatitis B-Virus, Hepatitis C-Virus, GB Virus C/Hepatitis G-Virus) (Hartwig Klinker).- VI. Vom Symptom zur Diagnose (Hartwig Klinker).- VI. 1 Fieber und/oder Gewichtsverlust.- VI. 2 Gastrointestinaler Symptomenkomplex.- VI. 3 Pulmonaler Symptomenkomplex.- VI. 4 Neurologisch-psychiatrischer Symptomenkomplex.- VI. 5 Ophthalmologischer Symptomenkomplex.- VII. Sonstiges.- VII. 1 Dermatologische Manifestationen bei HIV-Infektion.- VII. 1.1 Viren.- VII. 1.2 Bakterien.- VII. 1.3 Pilze.- VII. 1.4 Sonstige.- VII. 2 Neurologische Manifestationen (Eva Schielke).- VII. 2.1 Zerebrale Erkrankungen.- VII. 2.1.1 HIV-Enzephalopathie.- VII. 2.1.2 Zerebrale Toxoplasmose.- VII. 2.1.3 Kryptokokken-Meningitis.- VII. 2.1.4 Primäres ZNS-Lymphom.- VII. 2.1.5 Progressive multifokale Leukenzephalopathie (PML).- VII. 2.2 Erkrankungen des Rückenmarks und des peripheren Nervensystems.- VII. 2.2.1 HIV-assoziierte Myelopathie.- VII. 2.2.2 HIV-assoziierte akute Polyradikulitis (Guillain-Barré-Syndrom).- VII. 2.2.3 CMV-Myeloradikulitis.- VII. 2.2.4 HIV-assoziierte distal-symmetrische Polyneuropathie.- VII. 2.3 Erkrankungen der quergestreiften Muskulatur.- VII. 2.3.1 HIV-assoziierte Myopathie.- VII. 3 Häufigste Augenaffektionen (Hermann Gümbel).- VII. 4 Diagnose und Therapie der HIV-Infektion bei Kindern.- VII. 4.1 Betreuung von HIV1-exponierten und HIV1-positiven Kindern (Bernd Buchholz und Thomas Böhler).- VII. 4.1.1 Einleitung.- VII. 4.1.2 Betreuung von HIV1-exponierten Neugeborenen.- VII. 4.1.3 Ausschluss oder Diagnose der HIV1-Infektion.- VII. 4.1.4 Behandlung von HIV 1-positiven Kindern.- VII. 5 HNO-Manifestationen (Wilfried Pfitzer).- VII. 5.1 Äußeres Ohr/Gehörgang.- VII. 5.2 Mittelohr.- VII. 5.3 Innenohr.- VII. 5.4 Nasen- und Nasennebenhöhlen.- VII. 5.5 Mundhöhle.- VII. 5.6 Pharynx/Larynx.- VII. 5.7 Speicheldrüsen.- VII. 6 Zahnkomplikationen (Gernot Eigel).- VII. 7 Impfschutz (Klaus Fleischer).- VII. 8 Antiretrovirale Therapie bei HIV-infizierten Drogenkonsumenten Planung, Auswahl der Substanzen, Abfolge der Therapieregimes, Monitoring (Jörg Gölz).- VII. 8.1 Basisdiagnostik.- VII. 8.2 Integration des sozialen, toxicomanen, psychiatrischen und somatischen Syndroms zu einer Therapieplanung.- VII. 8.3 Compliance.- VII. 8.4 Somatische Komorbidität und Komedikation.- VII. 8.5 Antiretrovirale Therapiestrategien bei Drogenabhängigen.- VII. 9 Tipps zur Lebensführung.- VII. 10 Psychiatrische Krankheitsbilder und Behandlungsstrategien (Regina v. Einsiedel).- VII. 11 Psychotherapie bei HIV-Patienten (Petra Losse-Brust).- VII. 12 Schmerztherapie.- VII. 13 Ernährung (Achim Schwenk und Gisela Kremer).- VII. 13.1 Mangelernährung.- VII. 13.2 Methoden der Ernährungstherapie.- VII. 13.3 Medikamentöse Therapie der Mangelernährung.- VII. 13.4 Ernährungsprobleme und Lösungen.- VII. 14 Die Rolle des Hausarztes.- VII. 15 Klinische Bilder.- Abb. 1: Pneumocystis carinii-Pneumonie.- Abb. 2: Lymphom.- Abb. 3: Toxoplasmoseherde im Gehirn.- Abb. 4: Progressive multifokale Leukenzephalopathie (PML).- Abb. 5: Atypische Mykobakteriose.- Abb. 6: CMV-Retinitis.- Abb. 7: Orale Haarleukoplakie.- Abb. 8: Exiccationsekzem.- Abb. 9: Herpes zoster.- Abb. 10: Orale Candidose.- Abb. 11: Verrucae.- Abb. 12: Mollusca contagiosa.- Abb. 13: Psoriasis.- Abb. 14: Kaposi-Sarkom.- Abb. 15: Kaposi-Sarkom.- VII. 16 Literaturliste.- VIII. Adressenverzeichnis.
£61.74
Springer Fachmedien Wiesbaden Biologische Sicherheit im Labor: Ein kompakter
Book SynopsisIn kurzer und anschaulicher Weise gibt Thomas Binz einen Überblick über die biologische Sicherheit im Laborbereich. Die wichtigsten Elemente, wie die Zuteilung der Mikroorganismen zu Risikogruppen, die Bewertung der Risiken bei der Erzeugung von genetisch veränderten Mikroorganismen und die Elemente des Laboratoriums, die im Hinblick auf die biologische Sicherheit besonders relevant sind, werden unter Berücksichtigung der europäischen gesetzlichen Grundlagen dargestellt. Aufgrund des hohen Stellenwerts der Risikobewertung wird detailliert auf dieses Verfahren einschließlich anschaulicher Beispiele eingegangen. Das Buch soll nicht nur einen Überblick über die biologische Sicherheit geben, sondern auch zu ihrem Verständnis beitragen.Der AutorDr. Thomas Binz geht einer behördlichen Tätigkeit im Bereich Biologische Sicherheit nach (Bewilligungswesen, Abschätzung biologischer Risiken gentechnisch veränderter Organismen, nationale und internationale Rechtssetzung, Biowaffenkonvention). Er ist in verschiedenen nationalen und internationalen Ausbildungsprogrammen (Schweizerisches Biosafety Curriculum, Europäische Gesellschaft für Biosicherheit) eingebunden und unterrichtet im Rahmen des französischen 'Diplôme universitaire' für Biosicherheit der Universität Lille.Table of ContentsRisikobewertung.- Biosicherheitsstufe und Maßnahmen.- Biosicherung und Transport von infektiösem Material.
£11.77
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Medizinische Mikrobiologie und Infektiologie
Book SynopsisIn diesem Lehrbuch wird die medizinische Mikrobiologie von den allgemeinen Grundlagen über die Immunologie, die Diagnostik bis hin zur Chemotherapie dargestellt. Dabei sind die Kapitel zu den einzelnen Erregern besonders übersichtlich gestaltet. Um den klinischen Bezug deutlich zu machen, gibt es eine eigene große Sektion zu den Krankheitsbildern. Ein durchdachtes Konzept macht das Lernen leicht: Erreger-Steckbriefe zum schnellen Lernen Fallbeispiele Zusammenfassungen am Kapitelende Zahlreiche klinische Abbildungen Enge Vernetzung zwischen Erreger-Kapiteln und den Krankheitsbildern durch viele Querverweise Sämtliche Teilbereiche des Fachgebietes sind enthalten: Grundlagen, Immunologie, Diagnostik, Epidemiologie, Prävention, Hygiene, Bakteriologie, Virologie, Mykologie, Parasitologie, Chemotherapie, wichtige KrankheitsbilderDie HerausgeberProfessor Sebastian Suerbaum ist Vorstand des Lehrstuhls für Medizinische Mikrobiologie und Krankenhaushygiene am Max von Pettenkofer-Institut der Ludwig-Maximilians-Universität München Professor Gerd-Dieter Burchard ist tätig im Bernhard-Nocht-Institut für Tropenmedizin in Hamburg.Professor Thomas Schulz ist Direktor des Instituts für Virologie der Medizinischen Hochschule HannoverProfessor Stefan H.E. Kaufmann ist Direktor am Max-Planck-Institut für Infektionsbiologie in Berlin.Table of ContentsGrundlagen: Die Medizinische Mikrobiologie im 21. Jahrhundert.- Ursprung der Medizinischen Mikrobiologie.- Pathogenität und Virulenz.- Physiologische Mikrobiota: Regulation und Wirkungen, iatrogene Störungen und Probiotika.-One Health.-Immunologie: Immunologische Grundbegriffe- Zellen des Immunsystems.- Organe des Immunsystems.- Antikörper und ihre Antigene.- Komplement.- Antigen-Antikörper-Reaktion: Grundlagen serologischer Methoden.- Haupthistokompatibiltätskomplex. T-Zellen.- Phagozyten und antigenpräsentierende Zellen.- Immunpathologie.- Infektabwehr. Impfung. Diagnostik: Klinische Diagnostik und Probenentnahme.- Methoden der mikrobiologischen Diagnostik.- Epidemiologie und Prävention: Epidemiologie der Infektionskrankheiten.- Prävention der Infektionsausbreitung.- Krankenhaushygiene.- Bakteriologie: Bakterien: Definition und Aufbau.- Bakterien: Vermehrung u. Stoffwechsel.- Staphylokokken.- Streptokokken.- Enterokokken u. weitere katalasenegative grampositive Kokken.- Neisserien.- Enterobakterien.- Vibrionen, Aeromonas.-Nichtfermentierende Bakterien (Nonfermenter): Pseudomonas, Burkholderia, Stenotrophomonas, Acinetobacter.-Campylobacter.-Helicobacter.- Haemophilus.- Bordetella.- Legionellen.- Anthropozoonoseerreger ohne Familienzugehörigkeit: Listerien, Brucellen, Francisellen und Erysipelothrix.- Corynebakterien.- Bacillus.- Obligat anaerobe sporenbildende Stäbchen (Clostridien).- Obligat anaerobe, nicht sporenbildende Bakterien.- Mykobakterien.-Nocardien und andere aerobe Aktinomyzeten.- Treponemen.- Borrelien.- Leptospiren.-Rickettsiaceae (Rickettsia, Orientia) Anaplasmataceae (Anaplasma, Ehrlichia, Neorickettsien) und Coxiellaceae.- Bartonellen.- Mykoplasmen und Ureaplasmen.- Chlamydien.- Weitere medizinisch bedeutsame Bakterien.- Virologie: Viren – allgemeine Prinzipien.- Humane onkogene Viren.- Picornaviren.- Flaviviren.- Rötelnvirus.- Coronaviren.- Orthomyxoviren: Influenza.-Paramyxoviren.- Tollwutvirus.- Arenaviren.- Bunyaviren.- Filoviren.- Virale Gastroenteritiserreger.- Humane Immundefizienz-Viren (HIV-1, HIV-2).- Humane T-lymphotrope Viren (HTLV-1, HTLV-2)LV.- Parvoviren.- Papillomviren und Polyomaviren.- Adenoviren.- Herpesviren.- Hepatitisviren.- Pockenviren.- Prionen.- Mykologie: Allgemeine Mykologie.- Candida.- Cryptococcus.- Pneumocystis.- Aspergillus.-Mucorales.- Fusarium.- Weitere humanpathogene Pilze.- Dermatophyten.- Außereuropäische Systemmykosen.- Parasitologie: Allgemeine Parasitologie.- Protozooen.- Trematoden.- Zestoden.- Nematoden.- Ektoparasiten.- Antimikrobielle und antivirale Chemotherapie: Allgemeines.- Antibakterielle Wirkung.- Resistenz.- Pharmakokinetik.- Applikation u. Dosierung.- Nebenwirkungen.-Auswahl von antimikrobiellen Substanzen (Indikation).-β-Laktam-Antibiotika I: Penicilline.- β-Laktam-Antibiotika II: Cephalosporine.- Kominationen mit ß-Laktamase-Inhibitoren.- β-Laktam-Antibiotika III: Carbapeneme.- Glykopeptidantibiotika.- Aminoglykoside.- Tetracycline (Doxycyclin) und Glycylcycline.- Lincosamine (Clindamycin).- Makrolide.-Antimikrobielle Folsäureantagonisten.- Fluorchinolone.- Antimykobakterielle Therapeutika.- Weitere antibakterielle Substanzen.- Antimykotika.- Antivirale Chemotherapie.- Antiparasitäre Substanzen.- Krankheitsbilder: Fieber - Pathophysiologie und Differenzialdiagnose.- Sepsis -schwere Sepsis - septischer Schock.- Infektionen des Herzens und der Gefäße.- Infektionen des ZNS.- Augeninfektionen.- Infektionen des oberen Respirationstrakts.- Pleuropulmonale Infektionen.- Harnwegeinfektion.-Genitoanale und sexuell übertragbare Infektionen.- Infektionen der Knochen und Gelenke.- Haut- und Weichgewebeinfektionen.- Gastroenteritiden und Peritonitis.- Infektionen der Leber, der Gallenwege und des Pankreas.- Infektionen der Zähne und des Zahnhalteapparates.- Reisemedizin.- Migrationsmedizin.- Infektionen bei immunsupprimierten Patienten.- Biologische Waffen - eine neue Herausforderung an Diagnostik, Therapie, Klinik und Prävention.
£44.99
Spektrum Akademischer Verlag Janeway Immunologie
Book Synopsis
£6.95
New India Publishing Agency Making Foods Safe and Free From Pathogens
Book Synopsis
£49.00
New India Publishing Agency Introductory Microbiology
Book Synopsis
£40.36
New India Publishing Agency Microbial Biotechnology
Book Synopsis
£54.40
New India Publishing Agency Introductory Microbiology
Book SynopsisThe book is written for the college students to provide wide information about the fundamental aspects of microbiology. The book is designed in such a manner to understand all the basics, principles and recent trends in the field of microbiology. Enough diagrams and pictures are given then and there to understand the chapteIt also covers new concepts in microbiology such as environmental microbiology and biotechnology etc.Table of Contents1. Introduction 2. History of Microbiology 3. Introduction to Microscope 4. Groups of Microorganisms 5. Bacteria 6. Fungi 7. Algae 8. Protozoa 9. Virus 10. Microbial Metabolism 11. Control of Microorganisms 12. Microbial Genetics - Basic Concepts 13. Industrial Microbiology 14. Immunology - Host Defense Mechanism 15. Genetic Engineering and Biotechnology 16. Environmental Microbiology
£61.75
New India Publishing Agency Microbial Biotechnology
Book SynopsisMicrobial Biotechnology is wide-ranging, multi-disciplinary activities which include recombinant DNA techniques, cloning and the application of microbes to the production of goods from bread to antibiotics. This book is an attempt to highlight the significant aspects of the vast subject area of microbial biotechnology likes bioinformatics tool for PCR primer designing, fungal biotransformations, bioremediation by microbes, natural products from fungi, microbial diversity etc to provide a complete overview of the subject. It also addresses the role of bacterial plasmid in xenobiotic degradation, antimicrobial resistance in bacteria, ultraviolet-B radiation effect on microbes and human health. The book will be valuable to the researchers, biologist, microbiologist, scientists, post graduate students of microbiology, agriculture, biotechnology and medical science also.Table of Contents1. Bioinformatics Tool for PCR Primer Designing in Microbial Genomics by Dinesh Kumar and Dilip K Arora 2. Detection of the Non-ribosomally Assembled Toxic Cyanopeptides by Maria Estela Silva-Stenico, Augusto Etchegaray,Omar Teschke, Marli Fatima 3. Fungal Biotransformations. A Powerful Tool in Drug Metabolism Studies by Monica Tallarico Pupo , Keyller Bastos Borges, Warley de Souza Borges and Pierina Sueli Bonato 4. Methylotrophy in Bacteria - Concept and Significance by G. Selvakumar, Sehar Nazim and S. Kundu 5. Recent Advances in Plant Growth Promotion Mechanisms of Agriculturally Important Bacteria by R. Muthukumarasamy, V. S. Saravanan, V. R.Kumar, S. Natarajan & G. Revathi 6. Microbial Biocontrol Agents for Insects and Phytopathogens by S. Indira Devi and Ram Lal 7. Natural Products from Endophytic Fungi by M.B. C. Gallo, Denise O. Guimaraes, Luciano da S. Momesso, Monica T. Pupo 8. Marine Microbial Diversity and its Application in Biotechnology by Imelda-Joseph 9. The Importance of Extracellular Metal Immobilization for Rhizobium Persistence in Heavy Metal Contaminated Soils by Sofia Isabel Almeida Pereira and Etelvina Maria de Almeida Paula Figueira 10. Bioremediation. A Natural Approach for Heavy Metal Contaminated Sites by Anju Rani, Alok Kumar and Reeta Goel 11. Role of Bacterial Plasmid in Xenobiotic Degradation by Abdullah Altalhi, Bahig El deeb and Youssuf Gherbawy 12. Mechanisms Involved in Tolerance of Mycorrhizal Plants to Heavy Metals by K.S. Subramanian, M. Thangaraju and R.A. Jegan 13. Impacts of Ultraviolet-b Radiation on Microbes and Human Health. The Biotechnological Perspectives by R. P. Sinha, M. B. Tyagi and Ashok Kumar 14. Antimicrobial Resistance in Gram Positive and Gram Negative Bacteria. Progress and Challenges by Debajit Thakur, Minali Baishya, Barnali Sarma, Tarun Ch. Bora & Ratul Saikia 15. Molecular Systematics of Frankia - Actinorhizal Symbiosis by Balwinder Bajwa, Manprit Gill, Saubashya Sur, Asim Bothra and Arnab Sen
£108.66
New India Publishing Agency Objective Microbiology
Book SynopsisMicrobiology is one of the most important subject not only in Veterinary Sciences and Animal Husbandry but also in Medical sciences. This book is written based on the most relevant and current information of microbiology in the form of objective type questions so that everybody can read and understand it properly. The book is useful for scientists, teachers, students, officers, diagnosticians, laboratory technicians, public health professionals and medial personnel associated directly or indirectly with research, teaching, training, extension, diagnosis, epidemiology and control of diseases of microbial origin such as bacteria, parasite, virus, rickettsia, mycoplasma, chlamydia, fungi etc. The detailed information has also been provided on emerging and reemerging diseases of animals and humans. This book will provide up to date information of all the diseases of various etiologies which are of serious human and animal health threat globally. The objective type questions of various kinds on different diseases have been provided so that students, researchers, examinees, trainees etc can face any challenge with a certain degree of profound confidence. This book will be extremely useful to all the persons who are directly or indirectly involved in the diagnosis and epidemiological investigations of human and animal diseases and their welfare. Finally, all can enrich their knowledge on any aspects of microbiology from the book and clarify any doubts and concepts very easily and confidently.Table of Contents01. History of Microbiology 02. Microscopy and Staining 03. Prokaryotic and Eukaryotic cells 04. Immunology and Immune responses 05. Diseases caused by bacteria 06. Diseases caused by viruses 07. Genetic Engineering 08. Antimicrobials 09. Reproduction and Growth of bacteria 10. Bacterial Genetics 11. Recombinant DNA Technology 12. Staphylococcus 13. Streptococci 14. Bacillus 15. Clostridium 16. Listeria 17. Corynebacterium 18. Actinomyces 19. Nocardia 20. Mycobacterium 21. Enterobacteriaceae 22. Yersinia 23. Pasteurella 24. Actinobacillus 25. Haemophilus 26. Brucella 27. Bordetella 28. Neisseria 29. Moraxella 30. Pseudomonas 31. Vibrio and Campylobacter 32. Mycoplasma 33. Spirochaetes 34. Leptospira 35. Rickettsia 36. Chlamydia 37. Miscellaneous questions
£26.77
Springer Rheumatic Fever
Book SynopsisToday rheumatic fever is still the most common cause of heart disease in children and young adults in developing countries. This disease is typically associated with poverty, in particular with poor housing, overcrowding and inadequate medical care. Rheumatic fever has almost disappeared from economically developed countries; this trend has paralleled improvements in standards of living. However, the recent resurgence of rheumatic fever in middle-class families in the U. S. A. has re-emphasized the importance of this disease in the developed countries as well. Prevention and control of rheumatic fever and rheumatic heart disease is an important part of the WHO cardiovascular disease program. Based on earlier WHO experience, and on the magnitude of the problem, it was realized that concerted action was needed to combat this significant cause of cardiovascular morbidity and mortality. The present program has been developed on the principle that sound knowledge and reliable technology already exist for implementing community programs for the prevention and control of rheumatic fever and rheumatic heart disease with the intention of extending activities toward nationwide coverage. The first edition of this book was an excellent instrument to assist in the control of this disease. The present volume with dissemination of knowledge to health personnel will contribute to closing the gap between knowledge and implementation and it links with WHO's endeavors in prevention and control of rheumatic fever and rheumatic heart disease.Table of Contents1 Definitions, history, and geography.- Definitions of rheumatic fever and related terms.- Brief history of rheumatic fever.- Incidence and prevalence.- Community medicine and public health importance.- 2 Etiology and epidemiology.- Streptococcal infections.- Host factors.- Environment.- 3 Pathogenesis and pathology.- Pathogenesis.- Pathology.- 4 Clinical manifestations.- Mode of onset.- Carditis.- Joint involvement.- Jaccoud’s arthritis.- Chorea.- Subcutaneous nodules.- Erythema marginatum.- Other manifestations.- Duration of the rheumatic attack.- Rheumatic fever in the adult.- 5 Laboratory manifestations.- Evidence of a recent streptococcal infection.- Evidence of systemic inflammation.- Laboratory evidence of heart involvement.- 6 Diagnosis.- Jones criteria.- Critique of the criteria.- 7 Differential diagnosis.- Musculoskeletal conditions simulating rheumatic fever.- Conditions simulating chorea.- Other common diagnostic errors.- Cardiac conditions simulating rheumatic carditis and rheumatic heart disease.- 8 Treatment.- General measures and bed rest.- Antimicrobial treatment.- Analgesic and anti-inflammatory treatment.- Diuretics and cardiotonic medication.- Treatment of chorea.- 9 Sequels of rheumatic fever: chronic rheumatic heart disease.- Prognosis.- Mitral regurgitation.- Aortic regurgitation.- Mitral stenosis.- 10 Rheumatic recurrences.- Quantitative aspects.- Qualitative aspects.- 11 Prevention of recurrent attacks.- Continual parenteral prophylaxis.- Continual oral prophylaxis.- Duration of continual prophylaxis.- Obstacles to continual prophylaxis.- Mass prophylaxis.- 12 Prevention of first attacks of rheumatic fever.- Diagnosis of streptococcal pharyngitis.- Technique of taking a throat culture.- Diagnosis without a throat culture.- Treatment of streptococcal pharyngitis.- 13 Role of health care workers other than physicians in the control of rheumatic fever.- Health education.- 14 The future of rheumatic fever.- Streptococcal vaccine.- Other possible advances.- A future without vaccine.
£42.74
Springer Verlag, Singapore Integrated Omics Approaches to Infectious
Book SynopsisThis book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.Table of ContentsChapter 1_Genomic Classification of Human Pathogens. –Chapter 2_Metagenomics of Human Microbiome. –Chapter 3_Genomic Landscape of Novel Coronavirus (2019-Ncov) Towards Better Diagnosis and Efficient Antiviral Therapies. –Chapter 4_Deciphering the Role of Epigenetic Reprogramming In Host-Pathogen Interactions. –Chapter 5_Applications of Next Generation Sequencing In Infectious Pathogens. –Chapter 6_Bioinformatics Applications in Human Pathogens. –Chapter 7_ Non-Coding RNA Profiling: Potential Application in Infectious Diseases. –Chapter 8_ Microarrays: A Road Map to Uncover Host Pathogen Interactions. –Chapter 9_RNA Sequencing as Strategy to Understand Pathogenesis. –Chapter 10_ Non-Coding RNA as Drug Target against Infectious Diseases. –Chapter 11_ Emerging Transcriptional Approach for Identification of Drug Targets in Human Pathogens. –Chapter 12_ Proteogenomics Applications in Human Pathogens.–Chapter 13_Proteomic Strategies for Understanding Host Pathogen Interactions.–Chapter 14_Antimicrobial and Therapeutic Peptides. –Chapter 15_ Structural Proteomics Guided Design of Antimicrobial Drugs and Vaccines. –Chapter 16_Mechanism of Action of Antimicrobial Agents against Clinically Important Pathogens: A Proteomic Approach. –Chapter 17_Application of Lipidomics in Understanding Host Pathogen Interaction. –Chapter 18_Metabolomics: Advances and Applications In Human Pathogens. –Chapter 19_Host-Pathogen Interactions: Nature Inspired Sialic Acid Based Biointerface Materials. –Chapter 20_Nanoparticles as Therapeutic Nanocargos Affecting Epigenome of Microbial Biofilms. –Chapter 21_Challenges and Prospects in Omics Approach to Pathogens
£161.99
Springer Verlag, Singapore Role of Birds in Transmitting Zoonotic Pathogens
Book SynopsisZoonotic diseases pose a serious threat to global health and economy. Domestic and wild birds play crucial roles in transmission and spread of important zoonotic pathogens, with significant implications on human and avian health. Although zoonotic diseases have been extensively studied, information on various aspects of avian zoonotic pathogens have not been revisited or revised to any great extent. This book is a comprehensive and updated compilation of important zoonotic diseases that are transmitted by domestic and wild birds, and consists of 21 chapters that meticulously describe the (i) etiology and evolution, (ii) complex epidemiology, such as migration pathways in context of disease transmission, (iii) pathogenesis, (iv) clinical signs and necropsy findings, (v) diagnostics including latest molecular assays, and (vi) preventative and control strategies, with an emphasis on therapeutics and prophylaxis, of important zoonotic pathogens (bacterial, fungal, parasitic and viral) of avian origin in humans and birds. Each chapter is aptly supported by interactive tables and figures, and features an updated reference section. This book aims to create awareness and enlighten students of veterinary and human medicine on the role of birds in zoonoses, and would serve as a useful reference for working veterinarians, human doctors, and public health experts.Table of ContentsChapter 1_Introduction and Objectives.- Chapter 2. Presentation of bird migration.- Chapter 2.1.Taxonomic groups involved with migration.- Chapter 2.2. Evolution.- Chapter 2.3. Route of bird migration.- Chapter 2.4. Adaptations and population-level scale.- Chapter 2.5. Flyways and stop-overs.- Chapter 2.6. Significance in disease transmission.- Chapter 3. Bacterial Diseases.- Chapter 3.1. Campylobacter.- Chapter 3.1.1. Introduction.- Chapter 3.1.2. Etiology and classification.- Chapter 3.1.3. Epizootiology.- Chapter 3.1.4. Pathogenesis and mode of transmission.- Chapter 3.1.5. Campylobacteriosis in birds.- Chapter 3.1.6. Public health concerns.- Chapter 3.1.7. Clinical signs and pathological changes.- Chapter 3.1.8. Treatment and control.- Chapter 3.2. Chlamydiosis (Psittacosis, Ornithosis) .- Chapter 3.2.1. Historical background.- Chapter 3.2.2. Etiology and Classification.- Chapter 3.2.3. Epizootiology.- Chapter 3.2.4. Transmission between different birds.- Chapter 3.2.5. Chlamydiosis in Ducks and Geese.- Chapter 3.2.6. Chlamydiosis in human beings.- Chapter 3.2.7. Clinical signs and pathological changes.- Chapter 3.2.8. Treatment and control.- Chapter 3.3. Collibacillosis (E. coli) .- Chapter 3.3.1. Introduction and Historical background.- Chapter 3.3.2. Etiology and classification.- Chapter 3.3.3. Antigenic structure of E. coli.- Chapter 3.3.4. Virulence associated factors.- Chapter 3.3.5. Epizootiology.- Chapter 3.3.6. Escherichia coli ,Wild Birds and the public health concerns.- Chapter 3.3.7. Clinical signs and pathological changes.- Chapter 3.3.8. Treatment and control.- Chapter 3.4. Salmonellosis.- Chapter 3.4.1. Introduction.- Chapter 3.4.2. Etiology.- Chapter 3.4.3. Epizootiology.- Chapter 3.4.4. Wild birds as a carrier for Salmonellosis.- Chapter 3.4.5. Modes of transmission and Pathogenesis.- Chapter 3.4.6. Salmonellosis and public health concerns.- Chapter 3.4.7. Clinical signs and pathological changes.- Chapter 3.4.8. Treatment and control.- Chapter 3.5. Avian Tuberculosis.- Chapter 3.5.1. Introduction and Historical background.- Chapter 3.5.2. Etiology.- Chapter 3.5.2. Epizootiology.- Chapter 3.5.3. Pathogenesis.- Chapter 3.5.4. Mycobacterium in wild birds.- Chapter 3.5.5. Public health concerns to Mycobacteriosis.- Chapter 3.5.6. Clinical signs and pathological changes.- Chapter 3.5.7. Treatment and control. .- Chapter 3.6. Lyme Disease (Borrelia spp) .- Chapter 3.6.1. Introduction and Historical background.- Chapter 3.6.2. Etiology.- Chapter 3.6.3. Epizootiology.- Chapter 3.6.4. Avian Spirochetosis.- Chapter 3.6.5. Lyme Borreliosis in North America.- Chapter 3.6.6. Lyme Borreliosis in Europe.- Chapter 3.6.7. Pathogenesis.- Chapter 3.6.8. Clinical signs and pathological changes.- Chapter 3.6.9. Treatment and control.- Chapter 3.7. Avian Erysipeplas.- Chapter 3.7.1. Introduction and Historical background.- Chapter 3.7.2. Etiology.- Chapter 3.7.3. Epizootiology.- Chapter 3.7.4. Public health and animal health concerns.- Chapter 3.7.5. Erysiplothrix impact on the wild birds.- Chapter 3.7.6. Pathogenesis.- Chapter 3.7.7. Clinical signs and pathological changes.- Chapter 3.7.8. Treatment and control.- Chapter 3.8. Clostridia disease (Avian Botulism) .- Chapter 3.8.1. Introduction and Historical background.- Chapter 3.8.2. Etiology.- Chapter 3.8.3. Epizootiology.- Chapter 3.8.4. Public health concerns.- Chapter 3.8.5. Pathogenesis.- Chapter 3.8.6. Clinical signs and pathology.- Chapter 3.8.7. Treatment and control.- Chapter 3.9. Avian Cholera.- Chapter 3.9.1. Introduction and Historical background.- Chapter 3.9.2. Epizootiology.- Chapter 3.9.3. Pathogenesis.- Chapter 3.9.4. Public health and animal health concerns.- Chapter 3.9.5. Clinical signs and pathological changes.- Chapter 3.9.6. Impact of P. multocida on the wildlife populations.- Chapter 3.9.7. Treatment and control.- Chapter 3.10. Spotted Fever Group of Rickettsiales.- Chapter 3.10.1. Introduction and Historical background.- Chapter 3.10.2. Epizootiology and Pathogenesis.- Chapter 3.10.3. Clinical signs and pathology.- Chapter 3.10.4. Public health and animal health concerns.- Chapter 3.10.5. Treatment and control.- Chapter 4. Viral Diseases.- Chapter 4.1. Flaviviruses (West Nile Virus and Japanese encephalitis virus).- Chapter 4.1.1. Introduction and Historical background.- Chapter 4.1.2. Etiology.- Chapter 4.1.3. Epizootiology and pathogenesis.- Chapter 4.1.4. Natural Host and Age susceptibility.- Chapter 4.1.5. Mode of transmission and Incubation period.- Chapter 4.1.6. Clinical signs, Necropsy finding and Pathological changes.- Chapter 4.1.7. Disease in human.- Chapter 4.1.8. Prevention and control measures and vaccination protocols.- Chapter 4.2. Togavirus (Western Equine encephalitis virus).- Chapter 4.2.1. Introduction and Historical background.- Chapter 4.2.2. Etiology.- Chapter 4.2.3. Epizootiology and pathogenesis.- Chapter 4.2.4. Natural Host and Age susceptibility.- Chapter 4.2.5. Mode of transmission and Incubation period.- Chapter 4.2.6. Clinical signs, Necropsy finding and Pathological changes.- Chapter 4.2.7. Immune response and Diagnosis.- Chapter 4.2.8. Control measures and vaccination protocols.- Chapter 4.3. Avian Influenza.- Chapter 4.3.1. Introduction.- Chapter 4.3.2. Etiology and classification.- Chapter 4.3.3. Epizootiology.- Chapter 4.3.4. Incidence and distribution of AI.- Chapter 4.3.5. Hosts and Host restrictions.- Chapter 4.3.6. Methods of transmission.- Chapter 4.3.7. Public Health Concerns.- Chapter 4.3.8. AI impact on the wild life population.- Chapter 4.3.9. Domestic animal concerns regarding AI.- Chapter 4.3.10. Clinical signs.- Chapter 4.3.11. Treatment and control.- Chapter 4.4. Newcastle disease virus (NDV) and other avian paramyxoviruses.- Chapter 4.4.1. Introduction, Synonyms, and Historical background.- Chapter 4.4.2. Etiology and strain classification.- Chapter 4.4.3. Epizootiology.- Chapter 4.4.4. Geographical distribution and incidence of the NDV.- Chapter 4.4.5. NDV modes of spread.- Chapter 4.4.6.NDV Public Health Concerns.- Chapter 4.4.7. Clinical signs.- Chapter 4.4.8. Necropsy findings.- Chapter 4.4.9. Pathogenesis.- Chapter 4.4.10. Diagnosis and Control measures.- Chapter 4.4.11. Treatment and control.- Chapter 4.5. Circovirus.- Chapter 4.5.1. Introduction.- Chapter 4.5.2. Etiology and classification.- Chapter 4.5.3. Psittacine Beak and Feather Disease.- Chapter 4.5.4. Historical background and introduction.- Chapter 4.5.5. Epizootiology and modes of transmission.- Chapter 4.5.6. Pathogenesis.- Chapter 4.5.7. Public health and animal health concerns.- Chapter 4.5.8. Goose and Duck Circoviruses.- Chapter 4.5.9. Diagnosis and Control measures.- Chapter 4.6. Rotavirus.- Chapter 4.6.1. Introduction and Historical background.- Chapter 4.6.2. Etiology and classification.- Chapter 4.6.3. Epizootiology.- Chapter 4.6.4. Pathogenesis.- Chapter 4.6.5. Clinical signs and pathology.- Chapter 4.6.6. Control measures.- Chapter 4.7. Usutu virus.- Chapter 4.7.1 Introduction and Historical background.- Chapter 4.7.2. Etiology and classification.- Chapter 4.7.3. Epizootiology.- Chapter 4.7.4. Pathogenesis.- Chapter 4.7.5. Clinical signs and pathology.- Chapter 4.7.6. Diagnosis.- Chapter 4.7.7. Control measures.- Chapter 5. Parasitic diseases.- Chapter 5. Cryptosporidiosis.- Chapter 5.1. Introduction.- Chapter 5.1.1. Epizootiology.- Chapter 5.1.2. Modes of transmission.- Chapter 5.1.3. Prevalence of the cryptosporidiosis.- Chapter 5.1.4. Cryptosporidiosis in Canada Geese.- Chapter 5.1.5. Pathogenesis and Cryptosporidiosis in human beings.- Chapter 5.1.6. Diagnosis and Control measures.- Chapter 5.1.7. Treatment and control.- Chapter 5.2. Giardiasis.- Chapter 5.2.1. Introduction.- Chapter 5.2.2. Epizootiology.- Chapter 5.2.3. Mode of transmission.- Chapter 5.2.4. Pathogenesis.- Chapter 5.2.5. Giardiasis and Canada Goose.- Chapter 5.2.6 Giardiasis in human beings.- Chapter 5.2.7. Diagnosis and Control measures.- Chapter 5.2.8. Treatment and control.- Chapter 5.3. Role of birds in tick-borne diseases .- Chapter 5.3.1. Introduction.- Chapter 5.3.2. Epizootiology and Mode of transmission.- Chapter 5.3.3. Tick-borne diseases.- Chapter 5.3.4. CCHF and Dermanyssus gallinae.- Chapter 5.3.5. Diagnosis and Control measures.- Chapter 5.3.6. Treatment and control.- Chapter 6. Mycotic Diseases.- Chapter 6.1. Aspergillosis- Chapter 6.1.1. Introduction and Historical background- Chapter 6.1.2. Epizootiology- Chapter 6.1.3. Mode of transmission- Chapter 6.1.4. Pathogenesis- Chapter 6.1.5. Public health and animal health concerns- Chapter 6.1.6. Clinical signs and necropsy findings- Chapter 6.1.7. Diagnosis and Control measures- Chapter 6.1.8. Treatment and control- Chapter 6.2. Dermatophytosis (Favus) - Chapter 6.3. Dactylariosis- Chapter 6.4. Histoplasmosis- Chapter 6.5. Cryptococcosis. - Chapter 6.6. Role of birds as vectors of fluke worms (Trichobilharzia szidati) - Chapter 7. Sporadic diseases affecting wild birds and of non-zoonotic importance- Chapter 7.1. Mycoplsmosis- Chapter 7.2. Ornithobacterium rhinotraheale- Chapter 7.3. Avian Herpesvirus- Chapter 7.4. Avian Pox- Chapter 7.5 Avian adenoviruses- Chapter 7.6. Retrovirus infections- Chapter 7.7. Paplomaviruses and Polyomaviruses.- Chapter 8. Conclusions.- Chapter 9. Glossary- Chapter 10. List of abbreviations- Chapter 11. References.
£123.49
Springer Verlag, Singapore Textbook of Microbiology and Immunology
Book SynopsisThe fourth edition of Textbook of Microbiology and Immunology is an extensively revised edition , a healthy mixture of the old and the new contents. Many of the old traditional chapters have been retained with addition of new information along with the inclusion of new chapters more in line with the on-going changes in the syllabus and concepts in Medical Microbiology .While doing so, this book has blended the traditional organism-based learning and a syndrome based approach to infectious disease, together with the introduction of new and modified chapters incorporating the latest information in this field. The book provides an extensive coverage of fundamental topics in general and medical microbiology. The book also lays due emphasis on clinical microbiology with special focus on syndrome based approach to infectious diseases. It includes the basic concepts of microbiology as well as the recent updates and developments in the field of medical microbiology. All the topics havebeen incorporated in seven major sections: General microbiology, Immunology, Bacteriology, Virology, Mycology, and Applied and Clinical Microbiology. The dynamic nature of medical sciences with new guidelines and new diagnostic methods coming into the arena necessitates the incorporation of new information in each new edition of a book. This facet has been addressed with the inclusion of recent information on the various aspects of microbiology, infectious diseases and immunology, in the fourth edition of the Textbook of Microbiology andImmunology ,which makes it one of the most authoritative and informative textbooks in medical microbiology. The book is an effort to inform and engage a wide spectrum of readers including medical students , both undergraduates and postgraduates, and residents, and faculty. It aims to be a must-have companion book for graduate and advanced undergraduate as well as postgraduate students of medical microbiology, general and allied microbiology, and of immunology.
£100.13
Springer Verlag, Singapore The MicroRNA Quantum Code Book
Book SynopsisThis book tells the story of the discovery of microRNA (miRNA) quantum code, the basic theory of biological data science for medical investigation with miRNA, to its implementation. It explains the use of a new algorithm called the miRNA entangling target sorter (METS), based on the quantum computation algorithm, to give the etiologic analysis for diseases such as cancer, infectious diseases, and age-related disorders. Providing detailed descriptions to make the METS algorithm simple to grasp, it also explains the accumulated cutting-edged data for human diseases utilizing artificial intelligence (AI) for quantum miRNA language (miRNA qubit) (MIRAI). Further, it describes a discovery story for quantum miRNA surveillance against tumors and quantum miRNA immunity against viruses. Since this is a multidisciplinary field of study, crucial details on physics, mathematics, computer science, data science, virology, immunology, oncology, pathology, and biology are supplied.This book will support professional advancement for scientists, clinicians, educators, students, and science enthusiasts. The reader's knowledge of the subject and its practical medical applications will be enriched by the wealth of informative figures and supporting data.Table of ContentsRNA Controls RNA.- MicroRNA Qubit.- Matrix Multiplication for MicroRNA Qubit.- MicroRNA Quantum Computing.- Vital METS/MIRAI.- Etiologic Analysis for Human cancer.- Encounter with the unknown.- Diabetes Mellitus: Quantum microRNA Language with Artificial Intelligence (MIRAI) as an Early Diagnostic Tool for Type II Diabetes Mellitus for Sustainable Healthcare.- Thyroid Cancer: Quantum microRNA Language/Artificial Intelligence (MIRAI)-Based Etiologic Analysis of Thyroid Cancer by Serum/Plasma miRNA Panel Data.- Metabolic Disease and Alzheimer’s Disease.- Quantum MiRNA Immunity and Quantum MiRNA Surveillance.- Quantum MiRNA code.
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Springer Verlag, Singapore Non-traditional Approaches to Combat
Book SynopsisThis book provides a detailed overview of the progress and challenges of non-traditional approaches for tackling antimicrobial resistance. The first chapter covers the factors that make microbes more likely to develop multidrug resistance. The book goes on to discuss the antimicrobial properties of propolis, essential oils and other microbial constituents that are used or under investigation to treat multidrug-resistant infections. Additionally, it covers alternative compounds that work as antimicrobial agents, their mechanisms of action, and how they might be utilized in conjunction with conventional drugs to circumvent drug resistance. The book explores the application of phage therapy and recent advancements in phage-based infection control with an emphasis on multidrug-resistant infections and discusses drug repurposing as a strategy to develop new antimicrobial agents efficiently and expeditiously. Additionally, it discusses the uses of nanoparticles in the treatment of infections brought on by multidrug-resistant pathogens and examines the use of different nanotechnology-based approaches to fudge microbial resistance mechanisms. It concludes by reviewing recent studies on microbial quorum-sensing systems and focuses on the significance of quorum-sensing systems in controlling microbial resistance mechanisms and at the same time highlights the importance and role of antimicrobial stewardship program to fight microbial infections. The book is an invaluable source of knowledge and information for academics, basic and clinical researchers, clinicians, and paramedic staff involved in one way or the other in the development and use of antimicrobial agents and strategies to combat multidrug resistance.Table of ContentsChapter 1. Recent Strategies to Combat Multi-drug Resistance.- Chapter 2. Role of advanced therapeutic techniques to combat multi-drug resistance.- Chapter 3. Strategies to combat multidrug resistance by non-traditional therapeutic approaches.- Chapter 4. Treatment Strategies to Combat Multi-drug Resistance (MDR) in Bacteria.- Chapter 5. Alternative therapy options for pathogenic yeasts: Targeting virulence factors with non-conventional antifungals.- Chapter 6. Role of Bacteriophages as non-traditional approaches to combat multidrug resistance.- Chapter 7. Drug Repurposing: An Approach for Reducing Multi Drug Resistance.- Chapter 8. Quorum Sensing as an alternative approach to combatting multidrug resistance.- Chapter 9. Nanoengineering approaches to fight multidrug resistant bacteria.- Chapter 10. Quorum sensing mediated targeted delivery of antibiotics. Chapter 11. Metal chelation as a promising strategy to combat fungal drug resistance.- Chapter 12. Propolis: Natural Antibiotic to Combat Multi Drug-Resistant Bacteria.- Chapter 13. Therapeutic potential of Himalayan Ayurvedic herbs against multidrug-resistant fungal pathogens.- Chapter 14. Antimicrobial Stewardship Programme: Why is it needed?.
£151.99
Springer Verlag, Singapore Natural Product Based Drug Discovery Against
Book SynopsisThis book comprehensively reviews current and novel treatment strategies against human parasites, including protozoans and helminths, using natural products. The initial chapters summarize the conventional treatment strategies and natural-product based therapeutics against these parasites. It discusses biochemical tools and techniques for the discovery of natural product based drugs against human parasites. The book also covers the ingenious and innovative mechanisms to achieve drug resistance by the protozoan parasites and strategies to overcome the resistance. It entails mechanistic insight into the modulation of host immune responses to delay or inhibit parasite clearance and explores host-pathogen interactions that mediate immunity against subsequent parasite challenge. In turn, the volume helps in understanding the immunobiology of the parasites and tools to identify candidate vaccine antigens and novel delivery systems against the protozoan parasites. Lastly, it explores the role of advanced methods, including nanotechnology, marine bioprospecting, and microorganisms-derived biochemicals against the protozoan parasites.This book is useful for students and researchers of pharmacology, parasitology, zoology and other allied fields.Table of Contents
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Springer Gut Health and Metabolic Syndrome
Book SynopsisChapter 1. Gut Ecology and Metabolic Health: Understanding the Microbiome-Metabolic Syndrome Connection.- Chapter 2. Understanding the Gut Microbiota Blueprint: Insights into its Role in Metabolic Syndrome.- Chapter 3. Linking the Gut Microbiome to Metabolic Syndrome: Exploring the Pathways.- Chapter 4. Dietary Strategies for Metabolic Syndrome: Enhancing Gut Microbiome Health.- Chapter 5. Novel Therapies: Pharmacological Approaches to Modulate the Gut Microbiome in Metabolic Syndrome.- Chapter 6. Integrative Health: Combining Exercise, Lifestyle Changes, and Gut Microbiome for Metabolic Syndrome.- Chapter 7. Mind-Body Interactions: The Role of Psychosocial Factors, Stress, and the Gut Microbiome in Metabolic Syndrome.- Chapter 8. Unveiling the Gut Microbiome's Role in Obesity and Insulin Resistance.- Chapter 9. From Discovery to Application: Clinical Perspectives on Gut Microbiome Research in Metabolic Syndrome.- Chapter 10. Exploring the Ethical, Legal, and Societal Implications of Gut Microbiome Research in Metabolic Syndrome.- Chapter 11. Advances in microbiome sequencing technologies for studying gut health in Metabolic Syndrome. Chapter 12. Microbiome and Metabolic Biomarkers in Metabolic Syndrome.- Chapter 13. Microbiome-Driven Precision Nutrition in Metabolic Syndrome.- Chapter 14. Personalized Microbiome-Based Therapies for the treatment and management of Metabolic Syndrome.- Chapter 15. Future Trends in Gut Microbiome Research in Metabolic Syndrome.
£170.99
Taylor & Francis Ltd EpsteinBarr Virus 38 Infectious Disease and Therapy
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Taylor & Francis Ltd Sinusitis
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Taylor & Francis Ltd Synthetic Peptide Vaccine Models
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Taylor & Francis Ltd Herpes Simplex
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Taylor & Francis Ltd Multicultural Perspectives in Customer Behaviour Key Issues in Marketing Management
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Cambridge University Press Chemotherapeutic Targets in Parasites
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Cambridge University Press Modeling Disease Transmission and Its Prevention by Disinfection
Book SynopsisPathogenic microorganisms exploit a number of different routes for transmission and this book demonstrates how the spread of disease can be prevented through the practices of disinfection and controlling microbial growth.Trade ReviewReview of the hardback: ' … well written, and each chapter is extensively referenced'. The Journal of Medical MicrobiologyTable of ContentsPreface; 1. The transmission and prevention of disease C. J. Hurst and P. A. Murphy; 2. Strategies for modeling microbial colonization of the human body in health and disease R. A. Ross and M T Lee; 3. Role of pathogen monitoring in microbial risk assessment J. B. Rose, J. T. Lisle and C. N. Haas; 4. Estimating the risk of acquiring infectious disease from ingestion of water C. J. Hurst, R. M. Clark and S. E. Regli; 5. Bacterial resistance to potable water disinfectants M. H. Stewart and B. H. Olson; 6. Preventing foodborne infectious disease C. J. Hurst; 7. Disinfection of microbial aerosols S. Clark and P. Scarpino; 8. Transmission of viral infections through animate and inanimate surfaces and infection control through chemical disinfection S. A. Sattar and V. S. Springthorpe; 9. The role of chemical disinfectants in controlling bacterial contaminants on environmental surfaces D. J. Gaber, T. M. Cusack and E. Scott; 10. Sterilization and disinfection of medical devices A. B. Margolin and V. C. Chamberlain; 11. Ultraviolet light disinfection of water and wastewater P. F. Roessler and B. F. Severin; 12. Thermal inactivation of microorganisms G. Le Jean and G. Abraham; Index.
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Cambridge University Press Infectious Disease and HostPathogen Evolution
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Cambridge University Press Susceptibility to Infectious Diseases
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Cambridge University Press Bacterial Disease Mechanisms An Introduction to Cellular Microbiology
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Cambridge University Press Nanometer Technology Designs High Quality Delay Tests Frontiers in Electronic Testing 38
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Cambridge University Press Medical Implications of Biofilms
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Cambridge University Press Infectious Disease and HostPathogen Evolution
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Pearson Education Microbiology with Diseases by Body System
Book SynopsisAbout our authors ROBERT W. BAUMAN is a professor of biology and past chairman of the Department of Biological Sciences at Amarillo College in Amarillo, Texas. He has taught microbiology, human anatomy and physiology, and botany for over thirty years. In 2004, the students of Amarillo College selected Dr. Bauman as the recipient of the John F. Mead Faculty Excellence Award and he has been nominated for the one-time award every year since. He received an M.A. degree in botany from the University of Texas at Austin and a Ph.D. in biology from Stanford University. His research interests have included the morphology and ecology of freshwater algae, the cell biology of marine algae (particularly the deposition of cell walls and intercellular communication), environmentally triggered chromogenesis in butterflies, and terrestrial oil pollution remediation by naturally occurring bacteria. He is a member of the American Society of Microbiology (ASM) where he has helTable of Contents A Brief History of Microbiology The Chemistry of Microbiology Cell Structure and Function Microscopy; Staining; and Classification Microbial Metabolism Microbial Nutrition and Growth Microbial Genetics Recombinant DNA Technology Controlling Microbial Growth in the Environment Controlling Microbial Growth in the Body: Antimicrobial Drugs Characterizing and Classifying Prokaryotes Characterizing and Classifying Eukaryotes Characterizing and Classifying Viruses; Viroids; and Prions Infection; Infectious Diseases; and Epidemiology Innate Immunity Adaptive Immunity Immunization and Immune Testing Immune Disorders Microbial Diseases of the Skin and Wounds Microbial Diseases of the Nervous System and Eyes Microbial Cardiovascular and Systemic Diseases Microbial Diseases of the Respiratory System Microbial Diseases of the Digestive System Microbial Diseases of the Urinary and Reproductive Systems Applied and Industrial Microbiology Microbiology Ecology and Microbiomes
£256.72
John Wiley and Sons Ltd Evolution of Virulence in Eukaryotic Microbes
Book SynopsisA unique and timely review of the emergence of eukaryotic virulence in fungi, oomycetes, and protozoa, as they affect both animals and plants Evolution of Virulence in Eukaryotic Microbes addresses new developments in defining the molecular basis of virulence in eukaryotic pathogens.Trade Review“It should be of interest to evolutionary biologists, medical microbiologists and plant pathologists at postdoctoral and faculty levels.” (Microbiology Today, 26 November 2012) Table of ContentsPREFACE ix ACKNOWLEDGMENTS xi CONTRIBUTORS xiii PART I GENERAL OVERVIEWS 1 1 Population Genetics and Parasite Diversity 3Hsiao-Han Chang, Rachel F. Daniels, and Daniel L. Hartl 2 Evolution of Meiosis, Recombination, and Sexual Reproduction in Eukaryotic Microbes 17Wenjun Li, Elizabeth Savelkoul, Joseph Heitman, and John M. Logsdon, Jr. 3 Phylogenomic Analysis 44Andrew J. Roger, Martin Kolisko, and Alastair G. B. Simpson 4 Phylogenetics and Evolution of Virulence in the Kingdom Fungi 70Monica A. Garcia-Solache and Arturo Casadevall PART II POPULATION GENETICS AND EVOLUTIONARY APPROACHES 91 5 Malaria: Host Range, Diversity, and Speciation 93Ananias A. Escalante and Francisco J. Ayala 6 From Population Genomics to Elucidated Traits in Plasmodium Falciparum 111Sarah K. Volkman, Daniel E. Neafsey, Stephen F. Schaffner, Pardis C. Sabeti, and Dyann F. Wirth 7 Selective Sweeps in Human Malaria Parasites 124Xin-zhuan Su and John C. Wootton 8 Evolution of Drug Resistance in Fungi 143Jessica A. Hill, Samantha J. Hoot, Theodore C. White, and Leah E. Cowen 9 Discovery of Extant Sexual Cycles in Human Pathogenic Fungi and Their Roles in the Generation of Diversity and Virulence 168Richard J. Bennett and Kirsten Nielsen 10 Worldwide Migrations, Host Shifts, and Reemergence of Phytophthora Infestans, the Plant Destroyer 192Jean Beagle Ristaino 11 Experimental and Natural Evolution of the Cryptococcus Neoformans and Cryptococcus Gattii Species Complex 208Alexander Idnurm and Jianping Xu 12 Population Genetics, Diversity, and Spread of Virulence in Toxoplasma Gondii 231Benjamin M. Rosenthal and James W. Ajioka PART III FORWARD AND REVERSE GENETIC SYSTEMS FOR DEFINING VIRULENCE 247 13 Genetic Crosses in Plasmodium Falciparum: Analysis of Drug Resistance 249John C. Tan and Michael T. Ferdig 14 Genetic Mapping of Virulence in Rodent Malarias 269Richard Carter and Richard Culleton 15 Genetic Mapping of Acute Virulence in Toxoplasma Gondii 285L. David Sibley and John C. Boothroyd 16 Virulence in African Trypanosomes: Genetic and Molecular Approaches 307Annette Macleod, Liam J. Morrison, and Andy Tait 17 The Evolution of Antigenic Variation in African Trypanosomes 324Andrew P. Jackson and J. David Barry 18 Antigenic Variation, Adherence, and Virulence in Malaria 338Joseph Smith and Kirk W. Deitsch 19 Invasion Ligand Diversity and Pathogenesis in Blood-Stage Malaria 362Manoj T. Duraisingh, Jeffrey D. Dvorin, and Peter R. Preiser PART IV COMPARATIVE "OMICS" APPROACHES TO DEFINING VIRULENCE 385 20 Evolution of Virulence in Oomycete Plant Pathogens 387Paul R. J. Birch, Mary E. Coates, and Jim L. Beynon 21 Evolution and Genomics of the Pathogenic Candida Species Complex 404Geraldine Butler, Michael Lorenz, and Neil A. R. Gow 22 Evolution of Entamoeba Histolytica Virulence 422Upinder Singh and Christopher D. Huston 23 Sex and Virulence in Basidiomycete Pathogens 437Guus Bakkeren, Emilia K. Kruzel, and Christina M. Hull 24 Emergence of the Chytrid Fungus Batrachochytrium Dendrobatidis and Global Amphibian Declines 461Matthew C. Fisher, Jason E. Stajich, and Rhys A. Farrer 25 Impact of Horizontal Gene Transfer on Virulence of Fungal Pathogens of Plants 473Barbara J. Howlett and Richard P. Oliver 26 Evolution of Plant Pathogenicity in Fusarium Species 485Li-Jun Ma, H. Corby Kistler, and Martijn Rep 27 Genetic, Genomic, and Molecular Approaches to Define Virulence of Aspergillus Fumigatus 501Laetitia Muszkieta, William J. Steinbach, and Jean-Paul Latge 28 Cryptosporidium: Comparative Genomics and Pathogenesis 518Satomi Kato and Jessica C. Kissinger INDEX 545
£135.80
John Wiley and Sons Ltd Viral Infections and Global Change
Book SynopsisA timely exploration of the impact of global change on the emergence, reemergence, and control of vector-borne and zoonotic viral infections From massively destructive superstorms to rapidly rising sea levels, the world media is abuzz with talk of the threats to civilization posed by global warming.Trade Review“I learnt so much from the book and enjoyed reading it. It is definitely a welcome and timely addition to the biomedical literature.” (Microbiology Today, 1 August 2014) “The healthcare professionals and scientists best equipped to prevent an actual viral apocalypse will have Viral Infections and Global Change at hand, rather than a machete. Or maybe both.” (Clinical Infectious Diseases, 25 April 2014) Table of ContentsForeword xxi Preface xxiii Contributors xxv About the Editor xxix Part I General aspects 1 1 Climate Change And Vector-Borne Viral Diseases 3 Ying Zhang, Alana Hansen, and Peng Bi 1.1 Introduction 4 1.2 Epidemiology of VVD 4 1.3 Association between climatic variables and emerging VVD 6 1.4 Invasion of nonzoonotic vvd to humans 14 1.5 Implications and recommendations for prevention and control 14 References 16 2 Impact Of Climate Change On Vector-Borne Arboviral Episystems 21 Walter J. Tabachnick and Jonathan F. Day 2.1 Introduction 22 2.2 The complex factors influencing mosquito-borne arbovirus episystems 24 2.3 West Nile virus 25 2.4 Dengue in Florida 28 2.5 Bluetongue 29 2.6 Conclusions 31 Acknowledgement 32 References 32 3 Influence Of Climate Change On Mosquito Development And Blood-Feeding Patterns 35 William E. Walton and William K. Reisen 3.1 Introduction 36 3.2 Mosquito development 37 3.3 Blood-feeding patterns 46 References 52 4 Environmental Perturbations That Influence Arboviral Host Range: Insights Into Emergence Mechanisms 57 Aaron C. Brault and William K. Reisen 4.1 Introduction 57 4.2 The changing environment 59 4.3 Deforestation and the epizootic emergence of venezuelan equine encephalitis virus 62 4.4 Rice, mosquitoes, pigs, and japanese encephalitis virus 63 4.5 Culex pipiens complex, house sparrows, urbanization, and west Nile virus 66 4.6 Urbanization, global trade, and the reemergence of chikungunya virus 70 4.7 Conclusions 71 References 71 5 The Socio-Ecology Of Viral Zoonotic Transfer 77 Jonathan D. Mayer and Sarah Paige 5.1 Introduction 78 5.2 Historical perspective 78 5.3 Human–animal interface 79 5.4 Surveillance 79 5.5 Deforestation and fragmentation 80 5.6 Urbanization 81 5.7 Examples 82 5.8 Conclusion 84 References 84 6 Human Behavior And The Epidemiology Of Viral Zoonoses 87 Satesh Bidaisee, Cheryl Cox Macpherson, and Calum N.L. Macpherson 6.1 Introduction 88 6.2 Societal changes and the epidemiology of viral zoonoses 89 6.3 Viral zoonoses and human societal values 92 6.4 Human behavior and the epidemiology of vector-borne viral zoonoses 93 6.5 Human behavior and the epidemiology of respiratory viral zoonoses 96 6.6 Human behavior and the epidemiology of waterborne viral zoonoses 98 6.7 Human behavior and the epidemiology of wildlife-associated viral zoonoses 101 6.8 The role of human behavior in the control of viral zoonoses 103 References 104 7 Global Trave l, Trade, And The Spread Of Viral Infections 111 Brian D. Gushulak and Douglas W. MacPherson 7.1 Introduction 112 7.2 Basic principles 113 7.3 An overview of population mobility 113 7.4 The dynamics of modern population mobility 114 7.5 Human population mobility and the spread of viruses 115 7.6 The biological aspects of population mobility and the spread of viruses 117 7.7 The demographic aspects of population mobility and the spread of viruses 119 7.8 Potential impact of climate change 126 7.9 Conclusion 127 References 128 8 Effects Of Land-Use Changes And Agricultural Practices On The Emergence And Reemergence Of Human Viral Diseases 133 Kimberly Fornace, Marco Liverani, Jonathan Rushton, and Richard Coker 8.1 Introduction 134 8.2 Ecological and environmental changes 136 8.3 Agricultural change 139 8.4 Demographic changes 141 8.5 Land use, disease emergence, and multifactorial causation 143 8.6 Conclusion 145 References 145 9 Animal Migration And Risk Of Spread Of Viral Infections 151 Diann J. Prosser, Jessica Nagel, and John Y. Takekawa 9.1 Introduction 152 9.2 Does animal migration increase risk of viral spread? 152 9.3 Examples of migratory animals and spread of viral disease 157 9.4 Climate change effects on animal migration and viral zoonoses 166 9.5 Shifts in timing of migration and range extents 166 9.6 Combined effects of climate change, disease, and migration 167 9.7 Conclusions and future directions 169 Acknowledgements 170 References 170 10 Illegal Animal And (Bush) Meat Trade Associated Risk Of Spread Of Viral Infections 179 Christopher Kilonzo, Thomas J. Stopka, and Bruno Chomel 10.1 Introduction 180 10.2 Search strategy and selection criteria 180 10.3 The bushmeat trade 181 10.4 Bushmeat hunting and emerging infectious diseases 181 10.5 Risk factors and modes of transmission 183 10.6 Conservation and wildlife sustainability 184 10.7 Case study: The role of the bushmeat trade in the evolution of Hiv 185 10.8 Illegal trade of domestic animals and exotic pets 186 10.9 Discussion and future directions 187 10.10 Prevention and control: From supply and demand to health education techniques 187 10.11 New technologies 188 10.12 Collaboration: Multidisciplinary advances and next steps 189 10.13 Conclusion 190 Conflicts of interest 190 References 190 11 Biological Significance Of Bats As A Natural Reservoir Of Emerging Viruses 195 Angela M. Bosco-Lauth and Richard A. Bowen 11.1 Introduction 195 11.2 Bats as exemplars of biodiversity 196 11.3 Bats are reservoir hosts for zoonotic and emerging pathogens 197 11.4 Contact rate as a driver for emergence of bat-associated zoonoses 203 11.5 Potential impact of climate change on viruses transmitted by bats 205 11.6 Conclusions 206 References 206 12 Role And Strategies Of Surveillance Networks In Handling Emerging And Reemerging Viral Infections 213 Carlos Castillo-Salgado 12.1 Introduction 214 12.2 Global trend of viral infectious agents and diseases 214 12.3 Recognized importance of public health surveillance 215 12.4 Definition and scope of public health surveillance 216 12.5 Key functions and uses of disease surveillance 217 12.6 New expansion of surveillance by the ihr-2005 218 12.7 Emergence of new global surveillance networks 218 12.8 Global influenza surveillance and who’s pandemic influenza preparedness framework 219 12.9 Early warning surveillance systems 220 12.10 Innovative approaches for surveillance 222 12.11 Electronic and web-based information platforms for information reporting, sharing, and dissemination 222 12.12 Real-time and near real-time information 223 12.13 New updated statistical methods for tracking viral and infectious disease outbreaks 223 12.14 Using proxy and compiled web-based information from different sources 225 12.15 Incorporation of public–private partnerships in surveillance activities 226 12.16 Use of volunteer sentinel physicians 226 12.17 Improving guidelines and protocols for viral surveillance 226 12.18 Incorporating health situation rooms or strategic command centers for monitoring, analysis, and response in surveillance efforts 227 12.19 Challenges of viral and public health surveillance 228 References 229 13 Predictive Modeling Of Emerging Infections 233 Anna L. Buczak, Steven M. Babin, Brian H. Feighner, Phillip T. Koshute, and Sheri H. Lewis 13.1 Introduction 233 13.2 Types of models 234 13.3 Remote sensing and its use in disease outbreak prediction 235 13.4 Approaches to modeling and their evaluation 241 13.5 Examples of prediction models 244 13.6 Conclusion 250 References 250 14 Developments And Challenges In Diagnostic Virology 255 Luisa Barzon, Laura Squarzon, Monia Pacenti, and Giorgio Palù 14.1 Introduction 256 14.2 Preparedness 258 14.3 Challenges in diagnosis of emerging viral infections 259 14.4 Approaches to the diagnosis of emerging viral infections 260 14.5 Conclusions 267 Acknowledgement 268 References 268 15 Advances In Detecting And Responding To Threats From Bioterrorism And Emerging Viral Infections 275 Stephen A. Morse and Angela Weber 15.1 Introduction 276 15.2 Emerging, reemerging, and intentionally emerging diseases 276 15.3 Bioterrorism 278 15.4 Viruses as bioweapons 279 15.5 Impact of biotechnology 282 15.6 Deterrence, recognition, and response 284 15.7 Public health surveillance 288 15.8 Conclusion 291 References 291 16 Molecular And Evolutionary Mechanisms Of Viral Emergence 297 Juan Carlos Saiz, Francisco Sobrino, Noemí Sevilla, Verónica Martín, Celia Perales, and Esteban Domingo 16.1 Introduction: Biosphere and virosphere diversities 298 16.2 Virus variation as a factor in viral emergence: a role of complexity 299 16.3 High error rates originate quasispecies swarms 300 16.4 Evolutionary mechanisms that may participate in viral disease emergence 302 16.5 Ample genetic and host range variations of fmdv: a human epidemic to be? 304 16.6 The arbovirus host alternations: high exposure to environmental modifications 307 16.7 Arenaviruses: As an emerging threat 313 16.8 Conclusion 315 Acknowledgement 316 References 316 17 Drivers Of Emergence And Sources Of Future Emerging And Reemerging Viral Infections 327 Leslie A. Reperant and Albert D.M.E. Osterhaus 17.1 Introduction 328 17.2 Prehistoric and historic unfolding of the drivers of disease emergence 329 17.3 Proximal drivers of disease emergence and sources of future emerging and reemerging viral infections 334 17.4 Further insights from the theory of island biogeography 338 References 339 18 Spillover Transmission And Emergence Of Viral Outbreaks In Humans 343 Sunit K. Singh 18.1 Introduction 343 18.2 Major anthropogenic factors responsible for spillover 344 18.3 Major viral factors playing a role in spillover 347 18.4 Intermediate hosts and species barriers in viral transmission 349 18.5 Conclusion 349 References 349 Part II Specific Infections 353 19 New, Emerging, And Reemerging Respiratory Viruses 355 Fleur M. Moesker, Pieter L.A. Fraaij, and Albert D.M.E. Osterhaus 19.1 Introduction 356 19.2 Influenza viruses 359 19.3 Human metapneumovirus 362 19.4 Human coronaviruses: SARS and non-SARS 363 19.5 Human bocavirus 366 19.6 KI and WU polyomaviruses 367 19.7 Nipah and hendra viruses 368 19.8 Conclusion 369 19.9 List of abbreviations 369 References 370 20 Emergence Of Zoonotic Orthopox Virus Infections 377 Tomoki Yoshikawa, Masayuki Saijo, and Shigeru Morikawa 20.1 Smallpox, a representative orthopoxvirus infection: The eradicated non-zoonotic orthopoxvirus 377 20.2 Zoonotic Orthopoxviruses 379 Acknowledgement 387 References 387 21 Biological Aspects Of The Interspecies Transmission Of Selected Coronavi ruses 393 Anastasia N. Vlasova and Linda J. Saif 21.1 Introduction 393 21.2 Coronavirus classification and pathogenesis 397 21.3 Natural reservoirs and emergence of new coronaviruses 399 21.4 Alpha-, beta- and gamma coronaviruses: cross-species transmission 404 21.5 Anthropogenic factors and climate influence on coronavirus diversity and outbreaks 407 21.6 Conclusion 410 References 410 22 Impac t Of Environmental And Social Factors On Ross River Virus Outbreaks 419 Craig R. Williams and David O. Harley 22.1 Introduction 420 22.2 History of mosquito-borne epidemic polyarthritis outbreaks in australia and the pacific 420 22.3 RRV transmission cycles have a variety of ecologies 421 22.4 Typical environmental determinants of RRV activity 422 22.5 Social determinants of RRV disease activity 423 22.6 A Conceptual framework for understanding the influence of environmental and social factors on RRV disease activity 423 22.7 Climate Change and RRV 427 22.8 Conclusion 427 Acknowledgement 428 References 428 23 Infection Patterns And Emergence Of O’nyong-Nyong Virus 433 Ann M. Powers 23.1 Introduction 433 23.2 History of outbreaks 434 23.3 Clinical manifestations 435 23.4 Epidemiology 435 23.5 Factors affecting emergence 437 23.6 Conclusion 440 References 441 24 Zoonotic Hepa titis E: Animal Reservoirs, Emerging Risks, And Impact Of Climate Change 445 Nicole Pavio and Jérôme Bouquet 24.1 Introduction 446 24.2 HEV biology and classification 446 24.3 Pathogenesis in humans 449 24.4 Animal Reservoirs 451 24.5 Zoonotic and Interspecies Transmission of HEV and HEV-like viruses 454 24.6 HEV in the environment 456 24.7 Climate change and impact on HEV exposure 457 24.8 Prevention 458 24.9 Conclusion 458 Acknowledgement 459 References 459 25 Impact Of Climate Change On Outbreaks Of Arenaviral Infections 467 James Christopher Clegg 25.1 Introduction 467 25.2 Natural history of arenaviruses 468 25.3 Predicted climate changes 470 25.4 Arenaviral diseases and climate change 471 References 473 26 Emerging And Reemerging Human Bunyavirus Infections And Climate Change 477 Laura J. Sutherland, Assaf Anyamba, and A. Desiree LaBeaud 26.1 Introduction 478 26.2 Bunyaviridae family 478 26.3 Climate Change and Bunyaviridae: Climatic influences on transmission cycles and subsequent risk for transmission of bunyaviruses 482 26.4 Disease spread due to growing geographic distribution of competent vectors 485 26.5 using climate as a means for outbreak prediction 486 26.6 Future problems 489 References 489 27 Emerging Trend Of Astroviruses, Enteric Adenoviruses, And Rotavi ruses In Human Viral Gastroenteritis 495 Daniel Cowley, Celeste Donato, and Carl D. Kirkwood 27.1 Introduction 496 27.2 Emerging trends in rotaviruses 497 27.3 Emerging trends in enteric adenoviruses 501 27.4 Emerging trends in astroviruses 504 28 Emerging Human Norovirus Infections 517 Melissa K. Jones, Shu Zhu, and Stephanie M. Karst 28.1 Introduction 517 28.2 Norovirus epidemiology 518 28.3 Features of norovirus outbreaks 519 28.4 Clinical features of norovirus infection 521 28.5 Host Susceptibility 522 28.6 Effect of increased size of immunocompromised population 522 28.7 Effect of globalization of the food market on norovirus spread 523 28.8 Effect of climate change 525 References 525 29 Emergence Of Novel Viruses (Toscana, Usutu) In Population And Climate Change 535 Mari Paz Sánchez-Seco Fariñas and Ana Vazquez 29.1 Introduction 536 29.2 TOSV 536 29.3 USUV 542 29.4 Conclusions 550 30 Borna Disease Virus And The Search For Human Infection 557 Kathryn M. Carbone and Juan Carlos de la Torre 30.1 Introduction 558 30.2 Long-standing controversy around bdv as a human pathogen 559 30.3 A negative is impossible to prove, but do we have enough evidence to stop looking? 560 30.4 Recent improvements in testing for evidence of bdv in human samples 562 30.4.1 Serology 562 30.4.2 Nucleic acid tests 563 30.5 The possibilities for clinical expression of human bdv infection are myriad and almost impossible to predict 563 30.6 Epidemiology: the “new” frontier of human bdv studies? 565 30.7 Where do we go from here? 566 Acknowledgement 568 References 568 31 Tick-Transmitted Viruses And Climate Change 573 Agustín Estrada-Peña, Zdenek Hubálek, and Ivo Rudolf 31.1 Introduction 574 31.2 Ticks in nature 575 31.3 Family Flaviviridae 576 31.4 Family Bunyaviridae 583 31.5 Family Reoviridae 590 31.5.1 Colorado tick fever virus 590 31.5.2 Kemerovo virus 590 31.5.3 Tribeè virus 591 31.6 Family Orthomyxoviridae 591 31.6.1 Thogoto virus 591 31.6.2 Dhori virus 592 31.7 Other tick-transmitted viruses 592 31.8 Conclusions 592 Acknowledgements 594 References 594 32 The Tick–Virus Interface 603 Kristin L. McNally and Marshall E. Bloom 32.1 Introduction 604 32.2 Viruses within the tick vector 605 32.3 Saliva-assisted transmission 609 32.4 Summary and future directions 611 Acknowledgements 612 References 612 Index 617
£132.00
John Wiley and Sons Ltd Endodontic Microbiology 2e
Book SynopsisEndodontic Microbiology, Second Edition presents a comprehensive reference to the microbiology, pathogenesis, management, and healing of endodontic pathosis, emphasizing the importance of biological sciences in understanding and managing endodontic disease and its interaction with systemic health.Table of ContentsContributors ix Preface xi Preface to the First Edition xiii 1 Microbial Perspectives in the Twenty-First Century 1William Wade 2 Diagnosis, Epidemiology, and Global Impact of Endodontic Infections 11Dag Ørstavik 3 Microbiology of Dental Caries and Dentinal Tubule Infection 25Robert M. Love and Anne C.R. Tanner 4 Culture-Based Analysis of Endodontic Infections 51Gunnar Dahlén 5 Molecular Analysis of Endodontic Infections 81José F. Siqueira, Jr, and Isabela N. Rôças 6 Extraradicular Endodontic Infections 129Brenda P. F. A. Gomes and Ericka T. Pinheiro 7 Virulence of Endodontic Bacterial Pathogens 149Christine Sedgley 8 Viruses in Endodontic Pathosis 179Mohamed Sabeti 9 Fungi in Endodontic Infections 197Bilge Hakan Sen and B. Güniz Baksi 10 Severe Head and Neck Infections 231Jaime S. Brahim and Robert A. Ord 11 Endodontic Infections and Pain 251Anibal Diogenes and Ken M. Hargreaves 12 Systemic Antibiotics in Endodontic Infections 269Ashraf F. Fouad 13 Topical Antimicrobials in Endodontics 287Anil Kishen 14 Endodontic Infections in Incompletely Developed Teeth 311George T.J. Huang, Domenico Ricucci, and Louis M. Lin 15 Prognosis of Healing in Treated Teeth with Endodontic Infections 341Shimon Friedman 16 Endodontic Infections and Systemic Disease 385Ashraf F. Fouad Glossary 409 Index 413
£141.50
John Wiley & Sons Inc Understanding the Gut Microbiota
Book SynopsisThis book discusses the community of microbial species (the microbiota, microbiome), which inhabits the large bowel of humans. Written from the perspective of an academic who has been familiar with the topic for 40 years, it provides a long-term perspective of knowledge about this high profile and fast-moving topic.Table of ContentsPreface vii Acknowledgements ix 1 Introduction 1 References 4 2 Prime Facts 7 Summary 14 Explanation of Terms 15 References 16 3 A Sense of Community 19 Summary 33 Explanation of Terms 33 References 35 4 Assembling Communities 39 Summary 55 Explanation of Terms 55 References 56 5 Bowel Society 63 References 69 6 Chemostat Bowel 71 Summary 82 Explanation of Terms 82 References 83 7 Revealing Secret Lives 87 Summary 98 Explanation of terms 98 References 101 8 Remembrance of Microbes Past 105 Summary 111 References 112 9 Out of Tune: Dysbiosis 115 Summary 130 Explanation of Terms 130 References 132 10 We may be Lost, but we’re Making Good Time 139 Particularly Important Considerations 143 Running Out of Fuel? 145 The End of the Journey 146 References 146 Addendum: A Brief Summary of Technological Aspects of ]omics 149 General Features of Nucleic Acid-based Technology 149 Older Electrophoretic Methods for Screening Microbiota Compositions 150 Fluorescent Probes (FISH/FC) 151 Measuring the Abundance of Bacterial Groups by qPCR 152 Using DNA Chips to Screen Microbiota Compositions 153 Detailed Phylogenetic Analysis 154 Metagenomics: Determining the Functional Capacity of Microbiotas 155 Metatranscriptomics: Microbiota Biochemical Pathways in Action 156 Metaproteomics 157 Metabolomics 157 Summary 158 References 159 Index 163
£107.30
John Wiley & Sons Inc MALDITOF and Tandem MS for Clinical Microbiology
Book SynopsisThis book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss:Challenges of IdentifyingMycobacterium to the Species level Identification of Bacteroides and Other ClinicallyRelevant AnaerobesIdentification of Species inMixed Microbial PopulationsDetection of ResistanceMechanismsProteomics as a biomarkerdiscovery and validation platformDetermination of AntimicrobialResistance using Tandem Mass SpectrometryTable of ContentsList of Contributors xxi Preface xxix Part I MALDI-TOF Mass Spectrometry 1 1 A Paradigm Shift from Research to Front]Line Microbial Diagnostics in MALDI]TOF and LC]MS/MS: A Laboratory’s Vision and Relentless Resolve to Help Develop and Implement This New Technology amidst Formidable Obstacles 3Haroun N. Shah and Saheer E. Gharbia 2 Criteria for Development of MALDI]TOF Mass Spectral Database 39Markus Kostrzewa and Thomas Maier 3 Applications of MALDI]TOF Mass Spectrometry in Clinical Diagnostic Microbiology 55Onya Opota, Guy Prod’hom and Gilbert Greub 4 The Challenges of Identifying Mycobacterium to the Species Level using MALDI]TOF MS 93 5 Transformation of Anaerobic Microbiology since the Arrival of MALDI]TOF Mass Spectrometry 123Elisabeth Nagy, Mariann Abrok, Edith Urban, A.C.M. Veloo, Arie Jan van Winkelhoff, Itaru Dekio, Saheer E. Gharbia and Haroun N. Shah 6 Differentiation of Closely Related Organisms using MALDI]TOF MS 147Mark A. Fisher 7 Identification of Species in Mixed Microbial Populations using MALDI]TOF MS 167Pierre Mahe, Maud Arsac, Nadine Perrot, Marie]Helene Charles, Patrick Broyer, Jay Hyman, John Walsh, Sonia Chatellier, Victoria Girard, Alex van Belkum, and Jean]Baptiste Veyrieras 8 Microbial DNA Analysis by MALDI]TOF Mass Spectrometry 187 9 Impact of MALDI]TOF MS in Clinical Mycology; Progress and Barriers in Diagnostics 211Cledir R. Santos, Elaine Francisco, Mariana Mazza, Ana Carolina B. Padovan, Arnaldo Colombo and Nelson Lima 10 Development and Application of MALDI]TOF for Detection of Resistance Mechanisms 231Stefan Zimmermann and Irene Burckhardt 11 Discrimination of Burkholderia Species, Brucella Biovars, Francisella tularensis and Other Taxa at the Subspecies Level by MALDI]TOF Mass Spectrometry 249Axel Karger 12 MALDI]TOF]MS Based on Ribosomal Protein Coding in S10]spc]alpha Operons for Proteotyping 269Hiroto Tamura Part II Tandem MS/MS-Based Approaches to Microbial Characterization 311 13 Tandem Mass Spectrometry Analysis as an Approach to Delineate Genetically Related Taxa 313Raju V. Misra, Tom Gaulton, Nadia Ahmod, Min Fang, Martin Hornshaw, Jenny Ho, Saheer E. Gharbia and Haroun N. Shah 14 Mapping of the Proteogenome of Clostridium difficile Isolates of Varying Virulence 379Caroline H. Chilton, Saheer E. Gharbia, Raju V. Misra, Min Fang, Ian R. Poxton, Peter S. Borriello and Haroun N. Shah 15 Determination of Antimicrobial Resistance using Tandem MassSpectrometry 399Ajit J. Shah, Vlad Serafim, Zhen Xu, Hermine Mkrtchyan and Haroun N. Shah 16 Proteotyping: Tandem Mass Spectrometry Shotgun Proteomic Characterization and Typing of Pathogenic Microorganisms 419Roger Karlsson, Lucia Gonzales]Siles, Fredrik Boulund, Asa Lindgren, Liselott Svensson]Stadler, Anders Karlsson, Erik Kristiansson and Edward R.B. Moore 17 Proteogenomics of Pseudomonas aeruginosa in Cystic Fibrosis Infections 451Liang Yang and Song Lin Chua 18 Top]Down Proteomics in the Study of Microbial Pathogenicity 493Joseph Gault, Egor Vorontsov, Mathieu Dupre, Valeria Calvaresi, Magalie Duchateau, Diogo B. Lima, Christian Malosse and Julia Chamot]Rooke 19 Tandem Mass Spectrometry in Resolving Complex Gut Microbiota Functions 505Carolin Kolmeder, Kaarina Lahteenmaki, Pirjo Wacklin, Annika Kotovuori, Ilja Ritamo, Jaana Matto, Willem M. de Vos, and Leena Valmu 20 Proteogenomics of Non]model Microorganisms 529Jean Armengaud 21A Analysis of MALDI]TOF MS Spectra using the BioNumerics Software 539Katleen Vranckx, Katrien De Bruyne and Bruno Pot 21B Subtyping of Staphylococcus spp. Based upon MALDI]TOF MS Data Analysis 563Zhen Xu, Ali Olkun, Katleen Vranckx, Hermine V. Mkrtchyan, Ajit J. Shah, Bruno Pot, Ronald R. Cutler and Haroun N. Shah 21C Elucidating the Intra]Species Proteotypes of Pseudomonas aeruginosa from Cystic Fibrosis 579Ali Olkun, Ajit J. Shah and Haroun N. Shah References 588 Index 593
£130.10
American Society for Microbiology Clinical Virology
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Bent Tree Press Fundamentals of Microbiology for Allied Health
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Experiment The Whole-Body Microbiome: How to Harness
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