Biotechnology Books
Springer Nature Switzerland AG Essential Current Concepts in Stem Cell Biology
Book SynopsisThis textbook describes the biology of different adult stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal and cord blood stem cells and also covers induced pluripotent stem cells. Further, it includes a chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material.Based on the international masters program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and Tongji University Shanghai, the book is a valuable source for postdocs and researchers working with stems cells and also offers essential insights for physicians and dentists wishing to expand their knowledge.This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.Trade Review“The books ... ‘compactly and concisely discuss a specific bio-topic based on lectures for upper-level undergraduates, master’s and graduate students’: this means that both beginners and well-trained students can benefit from reading this and other books in the same collection. ... All chapters are decorated by clear and well-designed color illustrations. I am pretty sure the book will meet the reader’s expectations.” (Manuela Monti, European Journal of Histochemistry, Vol. 64, 2020)Table of Contents1. Hematopoietic stem cells2. Mesenchymal stem cells 3. Cord blood stem cells 4. Induced pluripotent stem cells 5. Epigenetic regulation in somatic cell reprogramming 6. MET in reprogramming 7. Extracellular vesicles 8. Neural stem cells 9. Neural stem cell niche 10. Human pluripotent stem cells and neural regeneration 11. Organoids 12. Ethical aspects of human stem cell research
£59.99
Springer Nature Switzerland AG Allelopathy: Potential for Green Agriculture
Book SynopsisAllelopathic studies may be defined in various aspects; weed against weed/crop and vice versa. This book focuses on the ways to utilize the allelopathic potential of weeds or crops for controlling weeds in the agroecosystems. Vigorous use of herbicides is poisoning our environment at an alarming rate; allelopathy can be employed as a useful alternative to control weeds naturally under field conditions. The book contains chapters on the history of allelopathy; allelopathic potential of several important crops (rice, wheat, sorghum, maize, mustard, sunflower) and weeds (members of Solanaceae, Convolvulaceae, Asteraceae, Verbenaceae). Moreover, it highlights how the allelopathic potential of these weeds and crops can be employed effectively to suppress weeds under field conditions. The book also discusses topics on the role of allelochemicals in agroecosystems; impact on local flora; biotic stress induced by allelochemicals; mechanism of action of allelochemicals and future prospective of allelopathy. Prepared with basic concepts and importance of allelopathy, this book is intended for the agricultural community, botanists, students and researchers.Table of Contents1. Preface 2. Foreword 3. Introduction 4. History of allelopathy 5. Allelopathy potential of important crops (i) Rice (ii) Wheat (iii) Sorghum (iv) Maize (v) Mustard (vi) Sunflower 6. Allelopathy potential of weeds belonging to the family (i) Asteraceae (ii) Convolvulaceae (iii) Solanaceae (iv) Verbenaceae 7. Role of allelochemicals in agroecosystems 8. Impact on local flora 9. Biotic stress induced by allelochemicals 10. Mechanism of action of allelochemicals 11. Future prospective
£44.99
Springer Nature Switzerland AG Introduction to Antibody Engineering
Book SynopsisThis highly readable textbook serves as a concise and engaging primer to the emerging field of antibody engineering and its various applications. It introduces readers to the basic science and molecular structure of antibodies, and explores how to characterize and engineer them. Readers will find an overview of the latest methods in antibody identification, improvement and biochemical engineering. Furthermore, alternative antibody formats and bispecific antibodies are discussed.The book’s content is based on lectures for the specializations “Protein Engineering” and “Medical Biotechnology” within the Master’s curriculum in “Biotechnology.” The lectures have been held at the University of Natural Resources and Life Sciences, Vienna, in cooperation with the Medical University of Vienna, since 2012 and are continuously adapted to reflect the latest developments in the field. The book addresses Master- and PhD students in biotechnology, molecular biology and immunology, and all those who are interested in antibody engineering.Table of Contents
£63.06
Springer Nature Switzerland AG A Practical Guide to Protein Engineering
Book SynopsisThis textbook introduces readers in an accessible and engaging way to the nuts and bolts of protein expression and engineering. Various case studies illustrate each step from the early sequence searches in online databases over plasmid design and molecular cloning techniques to protein purification and characterization. Furthermore, readers are provided with practical tips to successfully pursue a career as a protein engineer. With protein engineering being a fundamental technique in almost all molecular biology labs, the book targets advanced undergraduates and graduate students working in molecular biology, biotechnology and related scientific fields. Table of ContentsPart I: Chapter 1: A brief history of protein engineeringChapter 2: From DNA to functional protein – A refresherChapter 3: Basic laboratory and computational techniquesPart II:Chapter 4: Protein engineering strategiesChapter 5: Computational tools for protein engineeringChapter 6: Gene isolationChapter 7: Rational design Chapter 8: Directed evolutionChapter 9: Protein modificationPart III:Chapter 10: Career prospect of a protein engineerChapter 11: Conversations with protein engineers
£68.00
Springer Nature Switzerland AG Multifaceted Protocols in Biotechnology, Volume 2
Book SynopsisThis contributed volume, “Multifaceted Protocols in Biotechnology, Volume 2”, consists of multidisciplinary methods and techniques commonly used in biotechnology studies. There are two sections covered in this book – Ionic Liquid Related Techniques & Evergreen Biotechnology Techniques. A brief introduction supports each protocol to allow easy learning and implementation. The first section consists of three chapters covering studies in modern biotechnology focusing on the role of ionic liquid techniques in extracting secondary metabolites, enzyme stabilization and biomass processing. The second section covers evergreen methodologies. It comprises five chapters covering topics on microcarrier technology for cell culture; Polymerase Chain Reaction for non-halal sources detection in food; ELISA for biomarker identification; gamma ray-induced mutagenesis for enhancing microbial fuel cells; and the effect of temperature on antibacterial activity of Carica papaya seed extract. This book will be useful to graduate students, researchers, academics, and industry practitioners working in the area of biotechnologyTable of ContentsChapter 1Graviola Fruit Extraction by Ionic Liquid Microwave-assisted Extraction (IL-MAE) Daddiouaissa Djabir, and Azura AmidChapter 2Role of Ionic Liquids in the Enzyme Stabilization: A Case Study with Trichoderma ressie Cellulase Amal A. M. Elgharbawy, Md Zahangir Alam, and Muhammad MoniruzzamanChapter 3Role of Ionic Liquids in the Processing of Lignocellulosic BiomassAmal A. M. Elgharbawy, Md Zahangir Alam, Sharifah Shahira Syed Putra and Muhammad MoniruzzamanChapter 4Proliferation of rat amniotic stem cell (AFSC) on modified surface microcarrier.Nurhusna Samsudin, Yumi Zuhanis Has-Yun Hashim, Hamzah Mohd Salleh, and Azmir Ariffin.Chapter 5Application of spectroscopic methods for the analysis of non-halal meats in food products: A narrative reviewAbdul Rohman, Nurrulhidayah Ahmad FadzillahChapter 6Identification of Potential Biomarkers of Porcine GelatinNur Azira Tukiran, Amin Ismail, Haizatul Hadirah Ghazali & Nurul Azarima Mohd AliChapter 7Gamma Ray Mutagenesis on Bacteria Isolated from Shrimp Farm Mud for Microbial Fuel Cell Enhancement and Degradation of Organic WasteAyoub Ahmed Ali, and Azura Amid, Azhar MuhammadChapter 8Effect of temperature on antibacterial activity and fatty acid methyl esters of Carica papaya seed extractMuhamad Shirwan Abdullah Sani, Jamilah Bakar, Russly Abdul Rahman and Faridah AbasChapter 9Solid-state Fermentation of Agro-industrial Waste Using Heterofermentative Lacti Acid Bacteria. Oktaviani, Muhammad Yusuf Abduh, Dea Indriani Astuti, Mia RosmiatiChapter 10Synthesis of chitosan-folic acid nanoparticles as a drug delivery system for propolis compounds Marselina Irasonia Tan and Adelina Khristiani Rahayu
£44.99
Springer Nature Switzerland AG 3D Printing in Oral & Maxillofacial Surgery
Book SynopsisThis book is a comprehensive guide to 3D printing and 3D bioprinting methods and their application in oral and maxillofacial surgeries. Among the 3D printing methods considered are fused deposition modeling, selective laser sintering, photopolymer jetting, powder binder printing, and stereolithography, while the coverage of 3D bioprinting encompasses inkjet, microextrusion, and laser techniques. In each case, the relevance of the technique to oral and maxillofacial surgery is explained. In addition, the available inks and bioinks for 3D printing are reviewed. The roles of soft and hard tissue printing in oral and maxillofacial tissue engineering and the use of 3D printing in multi- and interfacial tissue engineering are then examined in depth. The particular value of 3D printing in the treatment of critically sized defects is discussed separately. Finally, up-to-date information is provided on guided tissue/bone regeneration using 3D printing. The book will be of interest to both oral and maxillofacial surgeons and biomedical engineers.Table of ContentsChapter 1) Introduction to 3D-printing in Oral and Maxillofacial Surgery.- Chapter 2) 3D-Printing Methods Applicable in Oral and Maxillofacial Surgery.- Chapter 3) 3D-Bioprinting in Oral and Maxillofacial Surgery.- Chapter 4) 3D-Printed Medical Modeling for Oral and Maxillofacial Surgeries.- Chapter 5) Application of 3D-Printing in Production of Dental Instruments.- Chapter 6) 3D-Printing in Treatment of Soft, Hard, and Critical-Sized Oral and Maxillofacial Tissue Defects.- Chapter 7) Application of 3D-Printing in Reconstruction of Oral and Maxillofacial Multi- and Interfacial Tissue Defects.
£54.99
Springer Nature Switzerland AG Fundamentals of RNA Structure and Function
Book SynopsisThis highly illustrated textbook provides an essential overview on RNA architecture and function, it offers insights into the RNA basics and also explains novel RNA technologies, such as CRISPR-Cas and their applications. In addition, the mRNA based vaccine technology, which has long been tested, also before the COVID-19 pandemic, is discussed and students receive a basic understanding of this important medical application.The textbook is written by Prof. Grover in collaboration with her students and has an easily accessible style. The book provides a great tool for young researchers and students in biology, biomedical engineering or biochemistry, looking for a compact introduction or refresher work on RNA, including the newest findings and technologies. It is an ideal starter to learn about several RNA specific topics and to research them further.Table of Contents1. RNA-Composition and Base Pairing.- 2. Architecture of RNA.- 3. Small Catalytic RNA.- 4. The Spliceosome: A Large Catalytic RNA.- 5. A Genomic Perspective on RNA.- 6. The mRNA and the New Vaccines.- 7. Riboswitches: Sensors and Regulators.- 8. Small Non-Coding RNA, miRNA in Gene Regulation.- 9. CRISPR-Cas Systems, The science and ethics of gene manipulation.- 10. Transcription.
£58.11
Springer Biosignal Acquisition and Processing
Book SynopsisChapter 1. Meet your Biosignals.- Chapter 2. Biosignals Sensor Creation.- Chapter 3. Arduino Essentials.- Chapter 4. Analog Signals.- Chapter 5. Data Transmission.- Chapter 6. Sampling.- Chapter 7. Live Streaming.-Chapter 8. Basic Primer on APIs.- Chapter 9. Real-time Analytics.- Chapter 10. Essentials of Data Processing.- Chapter 11. Working with Features.- Chapter 12. Frequency Domain.- Chapter 13. Signal Modulation.- Chapter 14. Machine Learning.- Chapter 15. Machine Learning Strikes Back.- Chapter 16. File Exploration.- Chapter 17. From Python to the World.- Chapter 18. Interchanging Data.- Chapter 19. Into the World Wild Web.- Chapter 20. Jazzing Up Your UIs.-Chapter 21. Tame Your Pages.
£59.99
Springer Silicon Nitride Bioceramics
Book SynopsisChapter 1 - Ceramic Biomaterials An Overview.- Chapter 2- Rationale for Silicon Nitride Bioceramics.- Chapte 3 - Silicon Nitride Tribology.- Chapter 4 - Silicon Nitride in Spine Surgery.- Chapter 5 - Silicon Nitride Wear Particles.- Chapter 6 - Additive Manufacturing of Silicon Nitride.- Chapter 7 - Silicon Nitride Composites.- Chapter 8 - Antimicrobial Properties of Silicon Nitride.- Chapter 9 - Surface Engineering of Silicon Nitride.- Chapter 10 - Osteointegration of Silicon Nitride.- Chapter 11 - Surface chemistry of silicon nitride in artificial joint environment.- Chapter 12 - A future perspective in ceramic bioscience.
£142.49
Springer ComputerAided and Machine LearningDriven Drug
Book SynopsisEchoes from the past, visions from the future: a journey into the Medicinal Chemistry and the Computational Drug Discovery.- Molecular Databases.- A Brief Introduction to Pharmacogenomics and Personalized Medicine in the Drug Design Context.- Machine Learning and Neural Networks Methods Applied to Drug Discovery.- Clustering of Small Molecules.- QSAR and Machine learning predictors.- Molecular docking: state-of-art scoring functions and search algorithms.- Drug Design in Motion: concepts and applications of classical Molecular Dynamics simulations.- Conformational sampling of proteins: methods for simulate protein plasticity and ensemble docking.- Free energy perturbation and free energy calculations ap-plied to drug design.- Ultra-large-scale Virtual Screening.- Experimental assays: chemical properties, biochemical and cellular assays, and in vivo evaluations.- Challenges faced in the development of computational methods for predicting pharmacokinetics behavior.- Exploring the Significance of Experimental and Computational Methods in Protein Structure Determination.- Molecular modeling strategies in drug design, development, and discovery targeting proteases.- Computational study of conformational changes in nuclear receptors upon ligand binding.- An Overview on Computational Methods Targeting the Endocannabinoid System.- Kinase Inhibitors and Computer-aided Drug Design Methods.- Prediction of Drug Metabolism with In Silico Models: A Case Study of Doping Detection.
£170.99
£189.99
Springer Topical Products and Dermal Drug Delivery
Book SynopsisChapter 1 Dermal drug delivery formulations and critical quality attributes.- Chapter 2 Evaporative metamorphosis in topical products.- Chapter 3 Classification of Topical Products.- Chapter 4 Sensorial Characterization and their impact on the treatment outcome.- Chapter 5 Lipid based drug delivery systems in topical delivery.- Chapter 6 Approaches to minimize the dermal absorption of drugs intended for locoregional activity.- Chapter 7 Regional molecular targets in the skin for treating cutaneous and neurological disorders.- Chapter 8 Repurposing of systemically administered drugs for topical treatments.- Chapter 9 In vitro permeation testing, an art and science of testing the topical products.- Chapter 10 Regulatory pathway of approval of dermatological products.- Chapter 11 Future technologies for delivery and sampling of drugs form the skin.- Chapter 12 Novel techniques of investigating dermatokinetics of drugs.- Chapter 13 Forced perfusion microdialyais technique.- Chapter 14 Emerging technologies in transdermal drug delivery.
£123.49
Springer Microalgae Horizons
Book SynopsisChapter 1 Introductory Chapter Microalgae: Past, Present, And Future Irections.- Chapter 2 Challenges Of Microalgae Production: From The Laboratory To Large Scale.- Chapter 3 Cultivation Conditions And Operating Modes In Large-Scale Microalgae Processes.- Chapter.4 Mathematical Modeling And Simulation Applied To Microalgae.-Chapter 5 Configurations And Design Of Bubble Column Photobioreactors For The Production Of Protein And Phycocyanin From Microalgal Biomass.- Chapter 6 Configurations Of Photobioreactors For Microalgae Cultivation In Third Generation Of Biorefinery.- Chapter 7 Microalgae-Derived Biohydrogen.- Chapter 8 Bio-Green Evolution: The Journey Of Microalgae Products From Lab To Market - An Overview Of Microalgae-Based Processes And Products Part I.- Chapter 9 Bio-Green Evolution: The Journey Of Microalgae Products From Lab To Market - Considerations And Recommendations - Part II.- Chapter 10 Large-Scale Microalgae Production: Considerations And Recommendations.- Chapter 11 Patent Mapping In Microalgae-Mediated Processes.- Chapter 12 Wastewater Treatment In Microalgae Cultivation Systems: Recommendations For Large-Scale Application.-Chapter 13 Large-Scale Harvesting Of Microalgae.- Chapter 14 Large-Scale Microalgae Drying.- Chapter 15building-Integrated Microalgae Photobioreactor: An Adaptive Solution To Urban Heat Island Mitigation.- Chapter 16 Bioremediation Of Effluents In Pilot-Scale Microalgae Cultivation Systems: A Case Study.- Chapter 17: Pilot-Scale Outdoor Microalgae Production: A Case Study.
£208.99
Springer Cardiovascular Explants
Book SynopsisForeword 1.- Foreword 2.- Serving the good of the patient in cardiovascular implantology: The 3Bs’ concept shall be heralded as the way to go.- Blood conduits for implantation in open surgery: From infancy to maturity.- Peripheral arterial disease: What you need to know.- Accessibility to treatment of all aortic side branches in endovascular aneurysm repair.- The SETA-Latecba stent graft: An Odyssey.- The docking zone in stent-grafts deployed transrenally: Expression of fibrinolytic activators and inhibitors in the internal capsule lying over the aorta.- Early adverse events following the deployment of Cook-Zenith stent-graft in the descending thoracic aorta: Examination of the explanted devices.- The challenge of the RVOT reconstruction: From palliative surgery to therapeutic advances.- The Ross procedure: A detailed analysis of the explanted valve and the polyester reinforcement prosthesis to tentatively explain adverse events.- Investigation of explanted bioprosthetic heart valves: A comprehensive evaluation platform.- Pericardia are still the most select sources to manufacture percutaneous heart valves.- Conclusion: How to select a peripheral vascular device? A clinician’s dilemma.- Postface: Spectacular achievements of Donghua University / Université Laval collaboration in education and research.
£109.99
Springer Harnessing Biotechnology Tools for Product Development
Book SynopsisAntimalarial Drug Resistance Markers in Plasmodium falciparum among Pregnant Women in Nigeria.- Assessment of Antibiotics Susceptibility Pattern of Gram-negative Bacteria Associated with Deteriorated Carrot and Cabbage from Markets in Nigeria.- Advancements in Bacillus anthracis Diagnostic and Treatment Techniques.- Biofilm Formation and Antibiotic Profile of Staphylococcus aureus Isolated from Food and Fomites in Selected Cafeterias.- Demographic Impact of Diarrheagenic Enterotoxigenic Escherichia coli Infection.- Genetic Modulation of Pgh1 in Multi-Drug Resistance Plasmodium falciparum to Antimalarial Drugs Used as Prophylaxis in Pregnancy.- Next-Generation Biotechnology Tool in Mitigation of Resistance to Carbamates Insecticides in Anopheles Gambiae.- Phylogenetic Analyses of Selected Underutilized Members of the Fabaceae Family based on DNA Barcodes.- Probiotic Properties And Safety Profilling of Lactobacillus Species Obtained From Fermented Beverages in Nigeria.- Hospital-Based Retrospective Study of Plasmodium falciparum and Salmonella enterica Co-infection on Gender Demography and Leucocytes.- Insecticide Resistance Markers in Anopheles gambiae Complex.- Reports on Plasmodium Falciparum Histidine-rich Protein 2/3 Gene Deletion and Utilized Methodological Approaches in Nigeria.- Antimalarial Drug Resistance: Newer Approaches to Mitigate the Process.- Impact of Climate Change on the Invasiveness of Mosquitoes in Nigeria.- Inhibitory Effects of Selected Phytoconstituents Against Steroid 5-Alpha Reductase Type-2 Target in Prostate Cancer.- Paratransgenesis: Overview, Current Perspectives, and Future Research Needs for Malaria Control.- Onychomycosis Disease Development, Treatment, and New Trends.- Potentials of Phages Against Antibiotic-Resistant Bacteria.- Prevalence of Malaria Infection Among Symptomatic Patients of Selected Healthcare Centers in Nigeria.- The Impact of Antibiotic Resistance Genes in Shigellosis.- Co-Expression of pfcrt and pfmdr1 Genes in Malaria Patients.- Differential Mosquito Attraction and Host Microbiota-Vector-Environment Complex.- PD-1/PD-L1 Inhibitors and Triple-Negative Breast Cancer (TNBC).- Local Knowledge Variation and use Pattern of Eggplant (Solanum species) in Southern Nigeria.- Beyond Foes and Friends: Deciphering the Gut Microbiome's Bidirectional Role in Breast Cancer.
£123.49
Springer Stem CellDerived Exosomes and Microvesicles
Book SynopsisAn overview of extracellular vesicles.- Isolation of exosomes from cell culture supernatants.- Quality control of extracellular vesicles derived from stem cells for clinical applications.- Preservation of Extracellular Vesicles.- Manufacturing and Quality Control of Mesenchymal Stem Cell-Derived Exosomes for Clinical Application.- New advances in stem cell-derived extracellular vesicle functionalization technology.- Mesenchymal stem cells derived extracellular vesicles in therapeutic applications.- Potentiality of stem cell-derived extracellular vesicles in the setting of metabolic-dysfunction associated steatotic liver disease (MASLD).- Current applications of endothelial progenitor cells derived extracellular vesicles: from animals to bedside.
£142.49
Springer Societies Past and Present
Book SynopsisChapter 1. Introduction: Human Groups, Globalization, and the Long Run.- Chapter 2. Our Common Humanity: Hominin Evolution, the Reasonable Actor, and Groups.- Chapter 3. The First Globalization: Foraging Bands on the Global Human Frontier, 100,000-12,000 BP.- Chapter 4. The Agricultural Revolution: Group Diversification, Domestication, and Expansion, 33,000-7000 BP (31,000-5000 BP).- Chapter 5. The Urban Revolution I: Chiefdoms and Other Complex Societies, 6000-1000 BCE (8000-3000 BP).- Chapter 6. The Urban Revolution II: Consolidation and Expansion of Complexity in Agrarian States, Empires, and Civilizations, 3500 BCE-1450 CE.- Chapter 7. The Second Globalization: Industrial Revolution and Global Conquest, 1450s-1910s CE.- Chapter 8. Building a Global Society: Accelerating Globalization, 1910s-2010s.- Chapter 9. Social Patterns of Developed States: Industrial Capitalist Democracies, 1910s-2010s.- Chapter 10. Social Patterns of Developing States: Globalizing the Industrial Revolution, 1910s-2010s.- Chapter 11. Conclusion: The Future, Social Evolution, and Theorizing Humans.
£123.49
Springer Tissue Repair and Regeneration
Book Synopsis Mechanisms Osteoblasts and Osteoclasts in Bone regeneration.- Role of hormones in regulation of regeneration.- Angiogenesis in Bone Regeneration.- Plasmacytoid dendritic cells and corneal wound healing.- Molecular mechanisms of cells in regeneration.- Dental tissue regeneration.- Role of biomaterials in progression of tissue regeneration.- Bone biology and bioactive glass in bone regeneration.- Regenerative therapy for osteoporosis.- Nanoparticle-mediated delivery for effective regeneration.- Reactive oxygen species signaling and skin regeneration.- Corneal epithelial wound healing.- Fetal wound regeneration.- Musculoskeletal tissue regeneration using fibrous biomaterials.- miRNA for wound regeneration.- Role of wound matrix in regeneration.- Nanofiber patch and cardiac regeneration.- Corneal wound and viral entry and healing.- Corneal epithelial wound healing mechanisms.- Cutaneous wound healing in porcine model.
£142.49
£79.32
De Gruyter Cannabis Chemistry and Biology: Fundamentals
Book SynopsisThis book serves as an introduction to graduate students and early career researchers on chemistry and botany of the cannabis plant. Cannabis botany, propagation, biotechnology, chemistry, cannabinoids and their biosynthesis, chemovars of cannabis and their identification as well as the other chemical classes of compounds known to exist in the plant. Analytical method are discussed to establish identity and Potency changes over the years in the United States. This book will build a base of knowledge on the complexity of cannabis chemistry. Features Introduction to the fundamental chemistry and botany of Cannabis. State of the art research on Cannabis sativa. The history, botany, major chemical classes of cannabis as well as methods of analysis and potency trends over several decades in the United States. Written by prominent scientists in the field of cannabis. The Cannabis Chemistry Subdivision of the American Chemical Society recently founded in 2022 the ElSohly Award sponsored by Heidolph North America in honour of Prof. Mahmoud A. ElSohly. This award provides researchers, students, and industry professionals with resources to present their work at the Spring National Meeting of the American Chemical Society at the ElSohly Award Symposium. More information: https://cann-acs.org/wp-content/uploads/2020/12/CANN-Postcard-Award.pdf
£70.77
£84.55
De Gruyter Biomaterials and Engineering for Implantology: In Medicine and Dentistry
Book SynopsisBiomaterials are composed of metallic materials, ceramics, polymers, composites and hybrid materials. Biomaterials used in human beings require safety regulations, toxicity, allergic reaction, etc. When used as implantable materials their biological compatibility, biomechanical compatibility, and morphological compatibility must be acessed. This book explores the design and requirements of biomaterials for the use in implantology.
£79.32
De Gruyter Industrial Chemistry: for Advanced Students
Book SynopsisBrings your chemistry curriculum to life. Along with the first volume „Industrial Chemistry“ (978-3-11-067106-3) it explains major chemical processes performed by industry and looks at how transformations affect the quality of our lives. It examines how necessary products are developed and marketed, while also discussing the various types of waste byproducts and shows practices in which many industries have made strides to improve or „green“ specific chemical processes.
£65.55
De Gruyter BioProducts: Green Materials for an Emerging Circular and Sustainable Economy
Book SynopsisThe book is focused on Bio Products derived from renewable resources processed by conventional catalytic thermochemical processes and or emerging bioprocessing techniques including fermentation and synthetic biology. It highlights some of these developments—from discovery, lab feasibility, scale up and eventual commercialization of interest and value in all the major sectors of the economy.
£76.95
De Gruyter Biomolecules: From Genes to Proteins
Book Synopsis Biochemistry is the study of the structure and functions of biological macromolecules such as nucleic acids, proteins, carbohydrates and lipids. The book is organized in five chapters which covers the basic concepts and fascinating chemistry of biomolecules. It also exposes students to different metabolic pathways and concept of energy in biological system, and provides valuable material for the students of Chemistry, Biochemistry, Biotechnology and Bioscience.
£54.62
Wiley-VCH Verlag GmbH Nanobiotechnology: Concepts, Applications and Perspectives
Book SynopsisNanotechnology is the key technology of the 21st century. The possibility to exploit the structures and processes of biomolecules for novel functional materials, biosensors, bioelectronics and medical applications has created the rapidly growing field of nanobiotechnology. Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments. It is divided into four main sections: * Interphase Systems * Protein-based Nanostructures * DNA-based Nanostructures * Nanoanalytics Each chapter describes in detail currently available methods and contains numerous references to the primary literature, making this the perfect "field guide" for chemists, biologists and materials scientists who want to explore the fascinating world of nanobiotechnology.Trade Review"For those wanting to know more about this emerging scientific area, this is an excellent starting point." Microbiology Today "....describes in detail all currently available methods of this novel field of research...a perfect guide for chemists, biologists, and material scientists who want to explore the fascinating world of nanobiotechnology." Polymer News "In summary, I would rate the book a >strong buy<. It is a high-quality text - well illustrated, and extensively referenced - that provides the first authoriative overview of this emerging field." SPIE Nanotechnology E-Bulletin "This book really does represent a fine collection of chapters by respected authors describing current thinking on this subject. The book represents a substantial and realistic compendium of the key concepts and realities of modern nanobiotechnology and should be on the purchaselist of all biologists, chemists, physicists and engineers wishing to acquaint or immerse themselves in this newley emerging technology." ChemBioChem "I truly believe that this book can serve as a textbook for graduate students, as an essential reference for active specialists, and as interesting reading material for general readers with a curiosity in bionanotechnology." small"Einen sehr guten Einblick in diese neuen Technologien liefert das vorliegende Buch, das in leicht verständlichem Englisch anschaulich die verschiedenen Stufen des derzeitigen Entwicklungsstandes relevanter Bereiche aufzeigt." Biotec- Fachmagazin für Biotechnologie "Durch die geschickte Auswahl von Beiträgen aus den unterschiedlichsten Gebieten von unterschiedlichen Autoren wird dieses vielseitige Thema umfassend behandelt. Dabei gelingt es den Editoren dem Leser einen vielseitigen Einblick in dieses spannende Zukunftsthema zu gewähren." Chemie-Online "Den Herausgebern gelingt es, dem Leser das enorme Potential der Nano-Bio-Welt zu erschließen." Arzneimittel-Forschung/Drug Research "Dieses Buch stellt das erste systematische und allumfassende Werk seiner Art dar. Es ist absolut zeitgemäß und wohl zurzeit das bestmögliche Hilfsmittel für Forscher, Dozenten, Industrieangehörige und Studenten. ... exzellenten Qualität des Dargebotenen. Jegliche Kritik wäre hier fehl am Platze! In diesem Sinne wünsche ich dem Fachgebiet Nanobiotechnologie und diesem Buch den größtmöglichen Erfolg." CIT - Chemie Ingenieur Technik "Gleich vorweg gesagt, die Lektüre des handlichen Werks ist faszinierend. In nicht weniger als 27 kurzen Kapiteln stellen international führende Experten viele der modernen Forschungsrichtungen aus der Nanobiotechnologie aus erster Hand dar. (...) So behandeln mehrere Kapitel besonders gut und ausführlich die Verwendung von Gold- und anderen Metallnanoteilchen für bioanalytische Zwecke. ... Nichtsdestoweniger sind die Beiträge ausnahmslos von hoher Qualität und auch für ernsthaft interessierte Studenten und Quereinsteiger gut lesbar. Insbesondere diese Leser werden von der im Vergleich zur Primärliteratur leichteren Zugänglichkeit der Themen profitieren. ... Stattdessen bleibt es bei einer hervorragend zusammengestellten Auswahl hochinteressanter Übersichtsartikel..." Nachrichten aus der ChemieTable of ContentsI INTERPHASE SYSTEMS Biocompatible inorganic devices Microfluidic "Lab-on-a-chip" devices Microcontact printing of proteins Cell-nanostructure interactions Networks of neuronal cells on silicon substrates II PROTEIN-BASED NANOSTRUCTURES S-Layers Engineered nanopores Genetic appoaches to particle assembly Microbial nanoparticle production Magnetosomes Bacteriorhodopsin technology Polymer nanocontainers Protein biomolecular motors Nanoparticle-biomaterial hybrid systems III DNA-BASED NANOSTRUCTURES DNA-protein nanostructures DNA-templated electronics DNA-based metallic nanowires Mineralization in nanostructured biocompartments DNA-gold-nanoparticle conjugates DNA nanostructures for mechanics and computing Nanoparticles as non-viral transfection agents IV NANOANALYTICS Quantum dot biolabeling Nanoparticle molecular labels Analysis of biomolecular structure by AFM and molecular pulling Force spectroscopy Biofunctionalized nanoparticles for SERS and SPR Bioconjucated silica particles in bioanalysis
£213.26
Wiley-VCH Verlag GmbH Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications
Book SynopsisThis second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.Trade Review"This textbook provides a concise overview of pharmaceutical biotechnology focusing on the industrial needs of recombinant drugs, processes, and clinical use." E-STREAMS "... international experts ... have provided precise and valuable information for the industrial experts, scientists, pharmacists, research managers..." American Journal of Therapeutics Table of Contents Preface PART I: CONCEPTS AND METHODS FOR RECOMBINANT DRUG PRODUCTION Pharmaceutical Biotechnology and Industrial Applications: Learning Lessons from Molecular Biology (Oliver Kayser, Heribert Warzecha) Procaryotic Cells in Biotech Production (Andriy Luzhetskyy, Gabriele Weitnauer, Andreas Bechtold) Mammalian Cells in Biotech Production (Maria J. De Jesus and Florian M. Wurm) Biopharmaceuticals from Plants (Heribert Warzecha) The Production of Biopharmaceuticals in Transgenic Animals (Heiner Niemann, Alexander Kind, Angelika Schnieke) Translation of New Technologies in Biomedicines: Shaping the Road from Basic Research to Drug Development and Clinical Application - and Back Again (Michael Balls, Andrew Bennett, David Kendall) PART II: BRINGING THE DRUG INTO ACTION - FROM DOWNSTREAMING TO APPROVAL Overview and Classification of Approved Recombinant Drugs (Theo Dingermann, I. Zundorf) Downstream Processing (Uwe Gottschalk) Characterization of Recombinant Proteins (Christoph Giese, Henning von Horsten, Stefan Zietze) Formulation Strategies for Recombinant Protein and Related Biotech Drugs (Gerhard Winter, Julia Myschik) Drug Approval in the European Union and United States (Gary Walsh) Patents in the Pharmaceutical Biotechnology Industry: Legal and Ethical Issues (David B. Resnick) Biosimilar Drugs (Walter Hinderer) Pharmacokinetics and Pharmacodynamics of Therapeutic Peptides and Proteins (Yi Zhang, Bernd Meibohm) PART III: VACCINES Scientific, Technical and Economic Aspects of Vaccine Research and Development (Jens Peter Gregersen) New Nanobiotechnological Strategies for the Development of Vectors for Cancer Vaccines (Sean M. Geary, Caitlin D. Lemke, Yogita Krishnamachari, Aliasger K. Salem) Recombinant Vaccines: Development, Production and Application (Luke Richard Le Grand Michaela White, Evan B. Siegel, Ross Thomas Barnard) PART IV: RECENT APPLICATIONS IN PHARMACEUTICAL BIOTECHNOLOGY In Silico and Ultra-high Throughput Screenings (uHTS) in Drug Discovery: An Overview (Debmalya Barh, Shoaib Ahmad, Atanu Bhattacharjee) Metabolic Engineering of Medicinal Plants and Microorganisms for the Production of Natural Products (O Kayser, J Hille, HJ Woerdenbag) Metabolomics as Bioanalytical Tool for Characterization of Medicinal Plants and their Phytomedical Preparations (Nizar Happyana, Remco Muntendam, Oliver Kayser) Integration of Biotechnologies for the Development of Personalized Medicine (Kewal Jain) Xenotransplantation in Pharmaceutical Biotechnology (Gregory J. Brunn and Jeffrey L. Platt) Nutraceuticals/Functional Foods for Improving Health and Preventing Disease (Jian Zhao) Index
£221.36
Wiley-VCH Verlag GmbH Surface-Functionalized Ceramics: For
Book SynopsisSurface-Functionalized Ceramics Focused coverage of making and using functional ceramic materials for a wide variety of scientific and technical applications Surface-Functionalized Ceramics provides a comprehensive overview of surface functionalization approaches for ceramic materials, including alumina, zirconia, titania, and silica, and their uses as sensors, chemical, and biological probes, chromatographic supports for (bio)molecule purification and analysis, and adsorbents for toxic substances and pollutants. Overall, the text provides a broad picture of the enormous possibilities offered by surface functionalization and addresses the current challenges regarding surface analysis, characterization, and stability. As a well-rounded resource, the text points out opportunities of surface-functionalized ceramics, their issues such as achieving surface stability and complex analysis, and how to counter them. Edited by two experts in the field of advanced materials surfaces, Surface-Functionalized Ceramics covers topics such as: Processing methods for advanced ceramics, surface modification of ceramic materials, and methods for electrokinetic surface characteristics Surface imaging and chemical surface analysis using atomic force microscopy Surface chemical analysis and ceramic-enhanced analytics Biological and living matter-surface interactions including protein adsorption mechanisms as well as bacteria behavior in terms of biofilm formation and prevention for antibacterial applications Mesoporous silica and organosilica biosensors for water quality and environmental monitoring, plus ceramic-based adsorbents in bioproduct recovery and purification For professionals, researchers, and academics in the fields of materials science, biotechnology, biotechnological industry, environmental sciences, and ceramics industry, Surface-Functionalized Ceramics is a one-stop reference on the subject that provides different approaches to obtain surfaces of ceramic materials that perform desired functions.Table of ContentsIntroduction to Ceramic Materials Processing Methods for Advanced Ceramics Surface Modification of Ceramic Materials Surface Imaging and Structure Methods for Chemical Surface Analysis: Atomic Force Microscopy Surface Chemical Analysis of Ceramics and Ceramic-Enhanced Analytics Methods for Electrokinetic Surface Characteristics Functionalized Surfaces and Interactions with Biomolecules Bacteria-Surface Interactions: Biofilm Formation and Prevention Carbon Nanomaterials for Antibacterial Applications Mesoporous Silica and Organosilica Biosensors for Water Quality and Environmental Monitoring Ceramic-Based Adsorbents in Bioproduct Recovery and Purification
£999.99
Wiley-VCH Verlag GmbH Applied Bioengineering: Innovations and Future Directions
Book SynopsisA comprehensive overview of the topic, highlighting recent developments, ongoing research trends and future directions. Experts from Europe, Asia and the US cover five core areas of imminent importance to the food, feed, pharmaceutical and water treatment industries in terms of sustainable and innovative processing and production. In the field of enzyme engineering, they summarize historic developments and provide an overview of molecular enzyme engineering, while also discussing key principles of microbial process engineering, including chapters on process development and control. Further sections deal with animal and plant cell culture engineering. The final section of the book deals with environmental topics and highlights the application of bioengineering principles in waste treatment and the recovery of valuable resources. With its cutting-edge visions, extensive discussions and unique perspectives, this is a ready reference for biotechnologists, bioengineers, bioengineers, biotechnological institutes, and environmental chemists.Table of ContentsList of Contributors XIX 1 Introduction 1Toshiomi Yoshida 1.1 Introduction 1 1.2 Enzyme Technology 2 1.3 Microbial Process Engineering 2 1.4 Plant Cell Culture 5 1.5 Animal Cell Culture 5 1.6 Environmental Bioengineering 6 1.7 Composition of the Volume 7 References 7 Part I Enzyme Technology 11 2 Enzyme Technology: History and Current Trends 13Klaus Buchholz and Uwe T. Bornscheuer 2.1 The Early Period up to 1890 13 2.2 The Period from 1890 to 1940 16 2.3 A New Biocatalyst Concept – Immobilized Enzymes 19 2.4 Expanding Enzyme Application after the 1950s 24 2.5 Recombinant Technology –A New Era in Biocatalysis and Enzyme Technology 27 2.6 Current Strategies for Biocatalyst Search and Tailor Design 32 2.7 Summary and Conclusions 39 Acknowledgment 40 Abbreviations 40 References 40 3 Molecular Engineering of Enzymes 47Maria Elena Ortiz-Soto and Jürgen Seibel 3.1 Introduction 47 3.2 Protein Engineering: An Expanding Toolbox 48 3.3 High-Throughput Screening Systems 56 3.4 Engineered Enzymes for Improved Stability and Asymmetric Catalysis 58 3.5 De Novo Design of Catalysts: Novel Activities within Common Scaffolds 65 3.6 Conclusions 69 References 69 4 Biocatalytic Process Development 81John M.Woodley 4.1 A Structured Approach to Biocatalytic Process Development 83 4.2 Process Metrics 83 4.3 Technologies for Implementation of Biocatalytic Processes 87 4.4 Industrial Development Examples 91 4.5 Future Outlook 95 4.6 Concluding Remarks 96 References 96 5 Development of Enzymatic Reactions in Miniaturized Reactors 99Takeshi Honda, Hiroshi Yamaguchi, and Masaya Miyazaki 5.1 Introduction 99 5.2 Fundamental Techniques for Enzyme Immobilization 100 5.3 Novel Techniques for Enzyme Immobilization 150 5.4 Conclusions and Future Perspectives 155 Abbreviations 156 References 157 Part II Microbial Process Engineering 167 6 Bioreactor Development and Process Analytical Technology 169Toshiomi Yoshida 6.1 Introduction 169 6.2 Bioreactor Development 170 6.3 Monitoring and Process Analytical Technology 196 6.4 Conclusion 203 Abbreviations 204 References 204 7 Omics-Integrated Approach for Metabolic State Analysis of Microbial Processes 213Hiroshi Shimizu, Chikara Furusawa, Takashi Hirasawa, Katsunori Yoshikawa, Yoshihiro Toya, Tomokazu Shirai, and Fumio Matsuda 7.1 General Introduction 213 7.2 Transcriptome Analysis of Microbial Status in Bioprocesses 214 7.3 Analysis of Metabolic State Based on Simulation in a Genome-Scale Model 219 7.4 13C-Based Metabolic Flux Analysis of Microbial Processes 223 7.5 Comprehensive Phenotypic Analysis of Genes Associated with Stress Tolerance 227 7.6 Multi-Omics Analysis and Data Integration 230 7.7 Future Aspects for Developing the Field 231 Acknowledgments 233 References 233 8 Control of Microbial Processes 237Kazuyuki Shimizu, Hiroshi Shimizu, and Toshiomi Yoshida 8.1 Introduction 237 8.2 Monitoring 238 8.3 Bioprocess Control 242 8.4 Recent Trends in Monitoring and Control Technologies 250 8.5 Concluding Remarks 253 Abbreviations 254 References 254 Part III Plant Cell Culture and Engineering 259 9 Contained Molecular Farming Using Plant Cell and Tissue Cultures 261Stefan Schillberg, Nicole Raven, Rainer Fischer, Richard M. Twyman, and Andreas Schiermeyer 9.1 Molecular Farming –Whole Plants and Cell/Tissue Cultures 261 9.2 Plant Cell and Tissue Culture Platforms 263 9.3 Comparison ofWhole Plants and In Vitro Culture Platforms 265 9.4 Technical Advances on the Road to Commercialization 267 9.5 Regulatory and Industry Barriers on the Road to Commercialization 271 9.6 Outlook 273 Acknowledgments 275 References 275 10 Bioprocess Engineering of Plant Cell Suspension Cultures 283Gregory R. Andrews and Susan C. Roberts 10.1 Introduction 283 10.2 Culture Development and Maintenance 286 10.3 Choice of Culture System 288 10.4 Engineering Considerations 291 10.5 Bioprocess Parameters 294 10.6 Operational Modes 296 10.7 Bioreactors for Plant Cell Suspensions 297 10.8 Downstream Processing 303 10.9 Yield Improvement Strategies 306 10.10 Case Studies 310 10.11 Conclusion 315 References 316 11 The Role of Bacteria in Phytoremediation 327Zhaoyu Kong and Bernard R. Glick 11.1 The Problem 327 11.2 Defining Phytoremediation and Its Components 329 11.3 Role of Bacteria in Phytoremediation 330 11.4 Examples of Phytoremediation in Action 342 11.5 Summary and Perspectives 343 References 344 Part IV Animal Cell Cultures 355 12 Cell Line Development for Biomanufacturing Processes 357Mugdha Gadgil andWei-Shou Hu 12.1 Introduction 357 12.2 Host Cell 359 12.3 Vector Components 360 12.4 Transfection 365 12.5 Integration of Foreign DNA into Host Chromosome 366 12.6 Amplification 369 12.7 Single-Cell Cloning 370 12.8 Selecting the Production Clone 373 12.9 Clone Stability 376 12.10 Conclusion 376 Acknowledgments 377 References 377 13 Medium Design, Culture Management, and the PAT Initiative 383Ziomara P. Gerdtzen 13.1 Historical Perspective on Culture Medium 383 13.2 Cell Growth Environment 384 13.3 Media Types 386 13.4 Medium Components 387 13.5 High MolecularWeight and Complex Supplements 400 13.6 Medium for Industrial Production 407 13.7 Conclusions 411 References 412 Further Reading/Resources 416 14 Advanced Bioprocess Engineering: Fed-Batch and Perfusion Processes 417Sarika Mehra, Vikas Chandrawanshi, and Kamal Prashad 14.1 Primary Modes of Bioreactor Operation 417 14.2 Fed-Batch Mode of Operation 419 14.3 Perfusion Mode of Bioreactor Operation 435 14.4 Use of Disposables in Cell Culture Bioprocesses 447 14.5 Analytical Methods to Monitor Key Metabolites and Parameters 450 14.6 Concluding Remarks 453 Nomenclature 455 References 456 Further Reading/Resources 468 Part V Environmental Bioengineering 469 15 Treatment of Industrial and Municipal Wastewater: An Overview about Basic and Advanced Concepts 471Jyoti K. Kumar, Parag R. Gogate, and Aniruddha B. Pandit 15.1 Types ofWastewater 471 15.2 Biological Treatment 471 15.3 Wastewater Regulations 473 15.4 Biological Treatment Processes 473 15.5 Aerobic Techniques 475 15.6 Anaerobic Techniques 488 15.7 Aerobic–Anaerobic Processes 495 15.8 Modified Biological Processes 496 15.9 Overall Conclusions 511 List of Acronyms/Abbreviations 512 List of Variables and Coefficients 513 References 514 16 Treatment of SolidWaste 521Michael Nelles, Gert Morscheck, Astrid Lemke, and Ayman El Naas 16.1 Biological Treatment of Source Segregated Bio-Waste 522 16.2 Mechanical–Biological Treatment of Mixed Municipal Solid Waste 538 16.3 Biological Treatment of AgriculturalWaste 542 16.4 Conclusion 542 References 542 17 Energy Recovery from Organic Waste 545Yutaka Nakashimada and Naomichi Nishio 17.1 Advantage of Methane Fermentation for Energy Recovery from Organic Matter 545 17.2 Basic Knowledge of Methane Fermentation of OrganicWastes 546 17.3 Conventional Methane Fermentation Process 549 17.4 Advanced Methane Fermentation Processes 551 17.5 Hydrogen Production from OrganicWastes 555 17.6 Upgrading of Biogas from OrganicWastes Based on Biological Syngas Platform 561 17.7 Conclusions 564 References 565 18 Microbial Removal and Recovery of Metals from Wastewater 573Michihiko Ike,Mitsuo Yamashita, and Masashi Kuroda 18.1 Microbial Reactions Available for Metal Removal/Recovery 574 18.2 Selenium Recovery by Pseudomonas stutzeri NT-I 583 18.3 Future Prospects 587 18.4 Conclusions 590 References 590 19 Sustainable Use of Phosphorus Through Bio-Based Recycling 597Hisao Ohtake 19.1 Introduction 597 19.2 Microbiological Basis 598 19.3 Bio-Based P Recycling 600 19.4 Other Options for P Recycling 604 19.5 Conclusions 607 References 609 Index 613
£153.85
Wiley-VCH Verlag GmbH Biomedical Photonic Technologies
Book SynopsisBiomedical Photonic Technologies A state-of-the-art examination of biomedical photonic research, technologies, and applications In Biomedical Photonic Technologies, a team of distinguished researchers delivers a methodical inquiry and evaluation of the latest developments in the field of biomedical photonics, with a focus on novel technologies, including optical microscopy, optical coherence tomography, fluorescence imaging-guided surgery, photodynamic therapy dosimetry, and optical theranostic technologies. Each discussion of individual technologies includes examples of their contemporary application in areas like cancer therapy and drug delivery. Readers will discover the major research advancements in biomedical photonics from the last 20 years, ascertaining the basic principles of formation, development, and derivation of biomedical photonics phenomena at a variety of scales. Readers will also find: A thorough introduction to advanced wide-field fluorescent microscopy for biomedicine Comprehensive explorations of fluorescence resonance energy transfer and optical coherence tomography for structural and functional imaging Practical exploration of coherent Raman scattering microscopy and biomedical applications, as well as fluorescence image-guided surgery Complete analyses of enhanced photodynamic therapy, optogenetics, and optical theranostics employing gold nanoparticles Perfect for biophysicists and applied physicists, Biomedical Photonic Technologies will also benefit bioengineers and biotechnologists in academia and in industry.Table of ContentsOPTICAL MICROSCOPY Optical Section Super-Resolution Microscope FLUORESCENCE RESONANCE ENERGY TRANSFER (FRET) Process of Fluorescence Emission Process and Properties of FRET The Donors-Acceptors Couple (D-A Couple) Theory of FRET Types of FRET Process Common Fluorescent Groups of FRET Optical Properties of D-A Couple in FRET System Qualitative FRET Detection Quantitative FRET Detection Common Instruments of FRET Signal Detection and Analysis Applications of FRET in Biomedicine OPTICAL COHERENCE TOMOGRAPHY (OCT) Imaging Mechanism of OCT OCT Functional Imaging Applications for OCT COHERENT RAMAN SCATTERING MICROSCOPY Introduction Coherent Anti-Stokes Raman Scattering Microscopy Stimulated Raman Scattering Microscopy Biomedical and Biological Applications of CRS Microscopy Prospects and Challenges FLUORESCENCE IMAGING GUIDED SURGERY Introduction Fluorescence Probes for Imaging Guided Surgeries Imaging Systems Typical Fluorescence Imaging Guide Surgeries Limitations and Challenges PHOTODYNAMIC THERAPY DOSIMETRY Introduction Implicit Dosimetry Explicit Dosimetry Biological Response Singlet Oxygen Luminescence Dosimetry Challenges and Perspectives OPTICAL TISSUE PHANTOMS FOR IMAGING AND SPECTROSCOPY Introduction Absorption, Scatter and Fluorescence Phantom Composition Typical Tissue Phantoms Methods for Measuring Optical Properties of the Phantoms Applications of Tissue Phantoms Future Prospects OPTICAL THERANOSTIC TECHNOLOGIES BASED ON PRECIOUS METAL NANOPARTICLES Optical Properties of Gold Nanoparticles (GNPs) GNPs-Mediated Optical Diagnostic Technology GNPs-Mediated Phototherapy for Cancer GNPs-Mediated Precision Treatment
£999.99
Wiley-VCH Verlag GmbH Biomaterials Effect on the Bone Microenvironment:
Book SynopsisBiomaterials Effect on the Bone Microenvironment Practical resource on clinical bone regeneration from a variety of related interdisciplinary researchers Biomaterials Effect on the Bone Microenvironment focuses on the structure-activity relationship between bone biomaterials and microenvironment regulation, presenting a systematic exposition from all aspects of biomaterials regulated microenvironment in bone regeneration and covering design strategies, applications, and mechanisms of biomaterials that regulate bone microenvironment, along with the methods for manufacturing biomaterials and their clinical translation. The subject’s potential challenges and future development direction are discussed, and the design and initiative principle of tailored biomaterials with various features, including bioactive components and physicochemical property, are elucidated in depth. Numerous biomaterials, including natural and synthetic, are summarized and compared. Their advantages and features are also evaluated, particularly in bone microenvironmental regulation and bone generation. Moreover, the stimulation mechanism of the microenvironment to bone generation is discussed in detail, including mechanical-support effect, redox effect, pro-angiogenesis effect, inflammatory immune effect, and anti-aging effect. Biomaterials Effect on the Bone Microenvironment provides further coverage of sample topics such as: Role of bone microenvironment and its associated biomaterials in modulation bone diseases, reviewing the biomaterials used to regulate bone microenvironment Relationship between biological factors of various materials and physiological functions in bone microenvironment Application of the third generation of biomaterials, which would regenerate the bone to regulate bone microenvironment Emerging biological material manufacturing technology and mechanisms of novel biomaterial modulating microenvironment for bone regeneration Future outlook of bone tissue engineering along with the general process of bone remodeling and regeneration With comprehensive coverage of one of the most promising and valuable candidates for clinical bone regeneration, Biomaterials Effect on the Bone Microenvironment is an ideal resource for materials scientists, biotechnologists, biochemists, bioengineers, orthopedists, and clinical chemists who want to stay on the cutting edge of this rapidly evolving field.Table of ContentsPreface ix 1 Bone Microenvironment 1Yingying Jing and Xiao Chen 1.1 Introduction 1 1.2 Bone Microenvironment and Diseases 9 1.3 Biomaterials and Bone Microenvironment 18 2 Materiobiological Effects Regulate the Bone Microenvironment 43Shuangshuang Chen 2.1 Bioactive Components Influence the Bone Microenvironment 44 2.2 Physicochemical Property Influence the Bone Microenvironment 59 3 Design and Application of Biomaterials to Regulate Microenvironment for Bone Regeneration 75Xiuhui Wang and Yingying Jiang 3.1 Natural Biomaterials for Bone Microenvironment Regulation 76 3.2 Synthetic Biomaterials for Bone Microenvironment Regulation 87 4 Fabrication Technologies of Biomaterials 107Qin Zhang and Xue Xu 4.1 Fabrication Technologies of Biomaterials 107 4.2 Fabrication Technologies of Hydrogels 114 4.3 Fabrication Technologies of Other Biomaterials 121 References 125 5 Mechanisms for Biomaterials Reconstruct Microenvironment in Bone Regeneration 129Yan Wei and Mengmeng Li 5.1 Mechanical Support Effect 129 5.2 Redox Effect 133 5.3 Pro-angiogenesis Effect 138 5.4 Inflammatory Immune Effect 144 5.5 Anti-Aging Effect 149 6 Biomaterials Regulating Bone Microenvironment in Clinical Application 157Zhen Geng, Xiaoxiang Ren, and Sicheng Wang 6.1 Introduction 157 6.2 Autogenous Bone Remodeling 158 6.3 Allogeneic Bone Regeneration 161 6.4 Clinical Effect of Biomaterials 165 6.4.1 Bone tissue engineering 168 6.5 Clinical Challenges and Opportunities 169 References 170 7 Conclusions and Perspectives 175Ke Xu, Yan Hu, and Han Liu 7.1 Bone Microenvironment Under Physiological and Pathological Conditions 175 7.2 Biological Effects Under Modulation of Materials 177 7.3 Design and Application of Biomaterials in Bone Regeneration 178 7.4 Fabrication Technologies 180 7.5 Microenvironment Under Biomaterial Regulation 181 7.6 Biomaterials in Clinical Experience 182 Index 185
£999.99
Wiley-VCH Verlag GmbH Point-of-Care Biosensors for Infectious Diseases
Book SynopsisPoint-of-Care Biosensors for Infectious Diseases Comprehensive resource covering key developments in biosensor-based diagnostics for infectious diseases With its overview of currently available technologies, Point-of-Care Biosensors for Infectious Diseases serves as a starting point for the successful development and application of pathogen biosensors in a point-of-care setting. Here, expert authors review current challenges in pathogen detection and the selection of suitable biomarkers, detail currently available biosensor platforms including electrochemical, piezoelectric, magnetic, and optical sensors, and cover technology development for point-of-care biosensors for viral, bacterial, and parasitic infections. Point-of-Care Biosensors for Infectious Diseases covers key topics such as: Fundamentals of biosensor detection, with a focus on optical and electrochemical techniques Organic and inorganic based nanomaterials for healthcare diagnostics Strategies for miniaturizing biosensor devices, and state-of-the-art integrated sensing platforms Latest trends in point-of-care biosensing systems to detect, diagnose, and monitor infectious diseases Providing comprehensive coverage of the subject, Point-of-Care Biosensors for Infectious Diseases is an excellent reference for all developers, researchers, and technology managers in the areas of molecular diagnosis, infectious diseases, biosensors, and related fields.Table of ContentsPreface xiii 1 Biosensors for Infectious Diseases-Fundamentals 1 Maheswata Moharana, Subrat K. Pattanayak, Fahmida Khan, and Sushma Dave 1.1 Introduction 1 1.2 Biosensors Fundamental Aspects 2 1.3 Classifications of Biosensor 3 1.3.1 Biorecognition Perspective 3 1.3.1.1 Nucleic Acid Biosensors 3 1.3.1.2 Protein–Receptor Biosensor 5 1.3.1.3 Enzymatic Biosensor 5 1.3.1.4 Whole-Cells Biosensors 5 1.3.1.5 Antibody-Based Biosensor 6 1.4 Transduction Through Signals 6 1.4.1 Electrochemical Biosensors 6 1.4.2 Optical 6 1.4.3 Thermometric (Calorimetric) 7 1.4.4 Mass-Sensitive 7 1.4.5 Electrical 8 1.5 Conclusions 8 References 9 2 Nuts and Bolts of Modern Biosensing Technology: Smart Health Diagnostic Devices 15 Itthipon Jeerapan, Gabriela Valdés-Ramírez, and Barbara Brunetti 2.1 Introduction 15 2.2 Nuts and Bolts for Point-of-Care (POC) Biosensor-Based Testing 17 2.2.1 Analytes 18 2.2.2 Receptors and Sensing Elements 18 2.2.3 Transducer 20 2.2.4 Signal Processing Unit 21 2.3 Advances in Biosensing Technology 21 2.3.1 Advanced Sensors for Detecting Pathogens 21 2.3.1.1 Biosensors for Bacteria Detection 22 2.3.1.2 Biosensors for Detecting Viruses 26 2.3.2 Advanced Biosensors for Monitoring Metabolites 33 2.4 Conclusion and Prospects 40 References 41 3 Disease Related Detection with Electrochemical Biosensors 49 Anulipsa Priyadarshini, Niharika Das, Saraswati Soren, Jashobanta Sahoo, Raghabendra Samantray, and Rojalin Sahu 3.1 Introduction 49 3.2 Electrochemical Biosensors 50 3.2.1 Materials 51 3.2.2 Working Principle 53 3.3 Immobilization of Different Biomolecules 54 3.4 Different Types of Techniques Used in EC Biosensors for Detection of Various Diseases 55 3.4.1 Voltametric Biosensor 55 3.4.2 Electrochemical DNA Biosensors 56 3.4.3 Impedance Biosensors 58 3.4.4 Amperometric Biosensors 58 3.4.5 Potentiometric Biosensors 60 3.4.6 Electrochemical Immunosensor 61 3.5 Conclusion and Future Direction 62 References 63 4 Biosensors for Point-of-Care (POC) Applications 69 The Flag Bearer of the Modern Medicinal Technology to Tackle Infectious Diseases Sumit Kumar, Garima Rathee, Gaurav Bartwal, and Pratima R. Solanki 4.1 Introduction 69 4.2 Classification of POC Biosensors for Detection of Infectious Diseases 71 4.2.1 Electrochemical-Based Biosensor 71 4.2.2 Fluorescence-Based Biosensor 72 4.2.2.1 Direct Fluorescence Biosensors for Infectious Diseases 72 4.2.2.2 Signal-on/off Fluorescent Biosensors for Infectious Disease POC Diagnostics 73 4.2.3 Surface Plasmon Resonance (SPR)-Based Biosensor 73 4.2.4 Surface-Enhanced Raman Scattering (SERS)-Based Biosensor 73 4.2.5 Chemiluminescence-Based Biosensor 74 4.2.6 Colorimetric-Based Biosensors 74 4.2.7 Magnetic-Based Biosensors 74 4.3 Modern Devices for the Detection of Infectious Diseases 75 4.3.1 Lab-on-a-Chip Devices and Lab-on-a-Disc Devices 75 4.3.2 Microfluidic Paper-Based Analytical and Lateral Flow Devices 76 4.3.3 Miniaturized PCR and Isothermal Nucleic Acid Amplification Devices 78 4.4 Scope and Challenges Associated with the Next-Generation POC Devices 79 4.5 Conclusion 79 References 80 5 Organic- and Inorganic-Based Nanomaterials for Healthcare Diagnostics 87 Komal Kashyap, Maheswata Moharana, Fahmida Khan, and Subrat K. Pattanayak 5.1 Introduction 87 5.2 Nanomaterials Based on Carbon Allotropes in Healthcare 88 5.3 Inorganic Nanomaterials in Health Diagnosis 91 5.4 Organic Nanomaterials in Healthcare Diagnosis 92 5.5 Future Prospects 95 References 95 6 CRISPR/Cas System 101 Applications in Diagnosis of Infectious Diseases Deepak Kumar Sahel and Mohd Azhar 6.1 Introduction 101 6.2 Nucleic Acids: Role in the Diagnosis 102 6.2.1 Deoxyribonucleic Acids 103 6.2.2 Ribonucleic Acids 103 6.3 Nucleic Acid Biomarkers in Infectious Diseases 104 6.4 Nucleic Acid Detection and Limitations 106 6.5 CRISPR/Cas System 108 6.5.1 Characteristics Features of Different Cas Effectors 110 6.5.2 CRISPR in Diagnostics 111 6.5.2.1 Cas9-Based Detection 112 6.5.2.2 Cas12-Based Detection 112 6.5.2.3 Cas13-Based Detection 116 6.5.2.4 Other Cas Effectors-Based Detection 117 6.6 Conclusion and Prospects 119 References 119 7 Role of Piezoelectric Biosensors 129 Jaykishon Swain, Subrat Swain, Durgesh Singh, Anirudha Jena, Raghabendra Samantaray, and Rojalin Sahu 7.1 Introduction 129 7.2 Types of Piezoelectric Biosensors 131 7.2.1 Inorganic Piezoelectric Material 131 7.2.2 Organic Piezoelectric Biosensors 133 7.3 Application of Piezoelectric Biosensor Devices 135 7.3.1 Immunosensors Based on Piezoelectric Material 135 7.3.2 Piezoelectric Device with Molecularly Imprinted Polymers 137 7.3.3 Piezoelectric Biosensors for Genetic Information 138 7.4 Conclusion 139 References 140 8 Metal/Metal Oxide Nanoparticles-Based Biosensors for Detection of Infectious Diseases 147 Dipak Maity, Gajiram Murmu, Satya R. Sahoo, Ankur Tiwari, Siddharth Ajith, and Sumit Saha 8.1 Introduction 147 8.2 Biosensors 148 8.2.1 Electrochemical Biosensors 148 8.2.2 Colorimetric Biosensors 150 8.2.3 Fluorescence Biosensors 151 8.3 Types of Infectious Diseases 153 8.4 Nanoparticles-Based Biosensors 156 8.4.1 Recognition of Pathogens 157 8.4.2 Metal/Metal Oxide Nanoparticles-Based Biosensors 157 8.4.2.1 Gold Nanoparticles 158 8.4.2.2 Magnetic Nanoparticles 158 8.4.2.3 Quantum Dots 159 8.4.2.4 Other Metal/Metal Oxide Nanoparticles 160 8.5 Metal/Metal Oxide Nanoparticles-Based Biosensors used for Infectious Diseases 160 8.5.1 Gold Nanoparticles (AuNPs) 161 8.5.2 Silver Nanoparticles (AgNPs) 163 8.5.3 Platinum Nanoparticles (PtNPs) 164 8.5.4 Copper Nanoparticles (CuNPs) 165 8.5.5 Zinc Oxide Nanoparticles (ZnONPs) 166 8.5.6 Miscellaneous Metal Oxide Nanoparticles 167 8.6 Comparative Studies of Biosensors for Infectious Diseases: Advantages and Limitations 171 8.6.1 Electrochemical Biosensors 171 8.6.2 Fluorescence-Based Biosensors 172 8.6.3 Colorimetric Biosensors 172 8.7 Conclusion and Future Prospects 173 Acknowledgment 174 References 174 9 Biosensors for Point-of-Care Applications: Replacing Pathology Labs by Bedside Devices 187 Mayukh Sinha, Sayak Banerjee, Sambit Majumdar, and Arindam Kushagra 9.1 Introduction 187 9.2 POCT Relevance in Healthcare 187 9.3 Self-Blood Glucose Monitoring 189 9.3.1 Introduction 189 9.3.2 Requirements for Self-Glucose Monitoring Device 189 9.3.3 Types of Sensor-Based Monitoring System 189 9.3.3.1 Continuous Glucose Monitoring (CGM) 189 9.3.3.2 Flash Glucose Monitoring (FGM) 190 9.4 Methods of Blood Glucose Monitoring 190 9.4.1 Enzymatic Assay Reaction 190 9.4.2 Detection Method 191 9.4.3 Errors Occuring in Blood Glucose Monitoring 191 9.4.4 POCT for Blood Glucose Monitoring 191 9.5 Blood Gas Analysis 192 9.5.1 Introduction 192 9.5.2 Methodologies 192 9.5.3 Electrochemical Sensors 192 9.5.4 Optical Sensors 192 9.5.5 Measurement of the Blood Gas Parameters 193 9.5.6 pH 193 9.5.7 PaCO2 193 9.5.8 PaO2 194 9.5.9 Glucose and Lactate Metabolites 195 9.5.9.1 Electrolytes 196 9.5.9.2 Hemoglobin, Bilirubin 196 9.5.10 POCT of Blood Gas Analysis 197 9.6 Urine Analysis 197 9.6.1 Introduction 197 9.6.2 Methodologies 198 9.6.2.1 Urine Dipsticks (Colorimetric Reagent Strip) 198 9.6.2.2 Lateral Flow Immunoassay (Rapid Test) 198 9.6.3 Measurement of the Parameters in the Urine Sample 200 9.6.3.1 Protein 200 9.6.3.2 Nitrite 201 9.6.3.3 Leukocytes 201 9.6.3.4 Bilirubin 201 9.6.3.5 Urobilinogen 202 9.6.3.6 Specific Gravity 202 9.6.3.7 Hemoglobin (Hb) 203 9.6.3.8 Ketone 203 9.6.3.9 pH 203 9.6.3.10 Glucose 203 9.7 Conclusion 204 References 204 10 Strategic Synthesis of Diagnostic Novel Materials Against Infectious Diseases 209 Hardik Shyam Churi and Sushma Dave 10.1 Introduction 209 10.2 Detection Needs at the POC 211 10.2.1 Nanomaterials for Malaria Parasites Detection 212 10.2.2 Nanomaterials for HIV 214 10.2.3 Nanomaterials for HBV 215 10.2.4 Nanomaterials for HPV 216 10.2.5 Nanomaterials for Dengue Virus 217 10.2.6 Nanomaterials for Ebola Virus 217 10.2.7 Nanomaterials for Mycobacterium Tuberculosis 218 10.2.8 Nanomaterials for Zika Virus 219 10.2.9 Nanomaterials for Biomarkers in Infectious Disease POCT 220 10.2.10 Nanomaterials for Pathogen Nucleic Acids 221 10.2.11 Nanomaterials for Antibodies and Proteins 222 10.3 Technology Advancements in Infectious Disease POCT 224 10.4 Futuristic Developments 224 References 225 11 Development of a Diagnostic Kit for Point-of-Care Biosensors: Fundamentals and Applications 235 Vijay Vaishampayan, Prabir Kulabhushan, Ishita Dasgupta, Ashish Kapoor, and Sarang P. Gumfekar 11.1 Introduction 235 11.2 Evolution of Biosensor 236 11.3 Biosensors for Point-of-Care Sensing 237 11.3.1 Fundamentals of Biosensor 237 11.3.2 Bioreceptors in Biosensor 238 11.3.3 Transducer in Biosensor 240 11.3.3.1 Electrochemical Biosensor 240 11.3.3.2 Potentiometric Biosensor 241 11.3.3.3 Amperometric Biosensor 241 11.3.3.4 Impedimetric Biosensors 241 11.3.3.5 Voltammetric Biosensors 241 11.3.3.6 Optical Biosensor 241 11.3.3.7 Gravimetric Biosensor 241 11.3.3.8 Acoustic Biosensors 243 11.3.4 Materials Used to Fabricate Biosensors 243 11.3.5 Biosensors for Infectious Diseases 243 11.3.6 Biosensor for the Detection of Dengue 243 11.3.7 Biosensors for Tuberculosis 246 11.3.8 Future Scope 246 11.4 Conclusion 247 Acknowledgment 248 References 248 12 Lab-on-a-Chip Devices for Point-of-Care Infectious Diseases Diagnostics 255 Snehal Jani, Vishakha Dave, Medha Pandya, Ranjeet Brajpuriya, and Sushma Dave 12.1 Introduction 255 12.2 Design of Lab-on-a-Chip Devices 257 12.2.1 Microfluidic Paper-Based Analytical Devices (μPADs) 258 12.2.1.1 Fabrication of Paper-Based Microfluidic Devices 259 12.2.2 Chip-Based Microfluidic LOCs 261 12.2.3 Chip-Based Microfluidic Device Substrate Materials 262 12.2.4 Fundamentals of Flow of Liquid in Microchannels 262 12.2.5 Sampling 263 12.2.6 Diagnostics Material/Biomarkers in Microfluidic Devices 263 12.2.7 Signal Generation and Detection 264 12.2.7.1 Electrochemical Method 264 12.2.7.2 Magnetic Particle Labeling 265 12.2.7.3 Optical Detection 265 12.3 LOC for Diagnosis of Infectious Diseases 266 12.3.1 LOC for Virus Detection 266 12.3.2 LOC for Detection of Bacteria 267 12.3.2.1 Future Perspectives and Conclusion 268 References 270 Index 275
£999.99
Wiley-VCH Verlag GmbH Stimuli–Responsive Materials for Tissue
Book Synopsis
£999.99
Wiley-VCH Verlag GmbH Bio-Nanomaterials: Designing Materials Inspired by Nature
Book SynopsisWritten by authors from different fields to reflect the interdisciplinary nature of the topic, this book guides the reader through new nano-materials processing inspired by nature. Structured around general principles, each selection and explanation is motivated by particular biological case studies. This provides the background for elucidating the particular principle in a second section. In the third part, examples for applying the principle to materials processing are given, while in a fourth subsection each chapter is supplemented by a selection of relevant experimental and theoretical techniques. Table of ContentsMolecular units Molecular recognition Cell adhesion Whole- cell censor structures Bio-hybrid silica-based materials Biomineralization Self- assembly
£116.96
Wiley-VCH Verlag GmbH Health Physics: Radiation-Generating Devices, Characteristics, and Hazards
The book bridges the gap between existing health physics textbooks and reference material needed by a practicing health physicist as the 21st century progresses. This material necessarily encompasses emerging radiation-generating technologies, advances in existing technology, and applications of existing technology to new areas. The book is written for advanced undergraduate and graduate science and engineering courses. It is also be a useful reference for scientists and engineers.
£999.99
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Career Management for Chemists: A Guide to Success in a Chemistry Career
Book SynopsisJohn Fetzer’s "Career Management for Chemists" provides ample, common-sense guidance on the key topics such as: Resumés and CVs, Staying Driven & Current, Personal Skills & Traits Networking, Teamwork & Leadership, Speaking & Listening Writing Research Papers, Mentoring, Behavior & Rewards The practical coverage reflects not only his long professional experience but also his insight that, especially in today’s changing workplace, expectations and strategies for career management require constant re-evaluation. Provides real, common-sense, and proven means to enrich and make more rewarding a technical career. Pre-publication comments from colleagues - "Not only the student who is taking his first steps in the scientific world would profit abundantly by mining this book for views and ideas on the different sides of his chosen career. Also the seasoned scientist will be stimulated to scrutinize his own habits and pick up new thoughts, thereby becoming a more skilled instructor of his younger colleagues." J. Andersson, University of Münster, Germany "As one of the international collaborators of Dr. John Fetzer, I want to warmly congratulate him. His efforts nicely summarize very important topics for all who work in scientific activities. But, at the same time, Career Management for Chemists also provides some real insights for many people who are not working in science. This is a nice guidebook on how to enrich our lives and help us to become more successful!! K. Jinno, Toyohashi University of Technology Trade ReviewFrom the reviews: This book has an incredibly broad scope and looks at both technical and non-technical areas, from keeping research records to dealing with difficult people. It is steeped in chemical terminology and anecdotes based on situations common to chemists, and so brings something fresh to the area. Fetzer himself stresses in the introduction that everyone works for themselves and that you can’t rely on anyone else to control or shape your career. Having established this essential truth, Fetzer shares his many years of experience in a style that is reassuring and supportive. Although more experienced chemists may find many of his points veer towards the ‘obvious’, younger scientists will find his insights on aspects such as conferences, collaboration and publishing invaluable in helping them understand how to be effective and have impact in the scientific community. For me, the book’s real strength lies in these sections, with it acting as a virtual mentor, sharing experiences and advice. The scope of the book is such that the individual topics can only be covered briefly, but as an experienced columnist, Fetzer captures the key points, which for most readers is all that is required. For example, scientists who are keen to develop their careers towards a management role will find the sections on dealing with others and working in and leading teams offer a practical summary of many management theories. The comprehensive bibliography points those interested to further information. ...The advice offered is universal and relevant to chemistry careers in the UK and internationally. I feel this book will have most value to chemists at the start of their careers as it distils many years on experience into straightforward tips on being an effective scientist. However, anyone seeking guidance or support for their professional life will find much of value in Fetzer’s encouraging and constructive book. Sara Shinton, Chemistry World, Vol. 1, No. 12, December 2004 "Career Management for Chemists provides ample, common-sense guidance on the key topics such as resumes and CVs, staying driven and current, personal skills and traits networking, teamwork and leadership, speaking and listening, writing research papers, behavior and rewards. … reflects not only his long professional experience but also his insight that, especially in today’s changing workplace, expectations and strategies for career management require constant reevaluation." (cpp 2005, Issue no. 2, 2005) "A useful handbook for chemists at all levels and at all career stages. … Not only are the chosen topics thought-provoking … but consideration of such would be advantageous for any scientist to keep in mind while journeying through the years of a career. … None of the career management books offers the combination of topics that Fetzer does, with the emphasis on one’s career as a journey … . would be useful for recent graduates … ." (Mary B. Satterfield, Analytical and Bioanalytical Chemistry, March, 2005) "John Feltzer believes that to be a good scientist one needs more than just good technical knowledge and research skills. … He explains how to achieve in technical area by keeping on learning; being part of a scientific community; writing and reviewing for journals; diversifying etc." (Book News on the Internet, January, 2005) "This is generally an almost exclusive view of the USA experience of science employment. … Finding mentors (or being a mentor), how to deal with negative situations, learning not to fight a battle under your opponent’s rules, how to avoid having one’s ethics compromised by others, moving from "pure" science into management, are topics all covered in various chapters. … A thorough reading, followed by regular re-reads as one’s career develops, will almost certainly significantly enhance almost anyone’s career pattern." (K. Jones, Chromatographia, Vol. 61(1-2), 2005) "This book has an incredibly broad scope and looks at both technical and non-technical areas, from keeping research records to dealing with difficult people. It is steeped in chemical terminology and anecdotes based on situations common to chemists … . will have most value to chemists at the start of their careers … . anyone seeking guidance or support for their professional life will find much of value in Fetzer’s encouraging and constructive book." (Sara Shinton, Chemistry World, Vol. 1(12), December, 2004) "In a truly scientific way, Fetzer begins by exploring the technical requirements for a specialist scientific career. … Fetzer clearly identifies … issues, such as communication … resume and interview preparation, skills assessment, teamwork and leadership. … In clear text he leads the reader through each aspect, providing pertinent examples, many from his own experiences. … The book is most readable and will provide useful guidance for all chemists … ." (Alan French, Chemistry in Australia, November, 2004) "John Fetzer’s … provides ample, common-sense guidance on the key topics such as: Resumes and CVs, Personal Skills & Traits Networking, Teamwork & Leadership, Speaking & Listening, Writing Research Papers, Mentoring, Behavior & Rewards. … reflects not only his long professional experience but also his insight that, especially in today’s changing workplace, expectations and strategies for career management require constant re-evaluation." (PROCESS Chemical and Pharmaceutical Engineering, Vol. 7(3), 2004) Table of ContentsAcknowledgements 1 Introduction – The career as a long trip 2 Technical Areas 2.1 Accepting Failure to Create Innovation in Experimentation 2.2 Keeping current – always learning 2.3 Specialist or Generalist? 2.4 Being a Part of the Scientific Community 2.4.1 General Remarks 2.4.2 Societies – Is it advantageous to belong to professional societies 2.4.3 Being Involved in Societies 2.4.4 Conferences – Is it advantageous to attend and present at conferences? 2.4.5 Journals and other Publications – Is it advantageous to publish papers? 2.4.6 Reviewing for Journals 2.4.7 Advisory Boards and Editorships 2.5 Thinking – Curiosity and Wonder 2.6 Thinking – Scepticism 2.7 Diversifying 2.8 Parochial science – Possessiveness and Boundaries 2.9 The Tools (Part 1) – Tools and mechanics of research: Putting together your toolbox 2.10 The Tools (Part 2) – Handy tools, but not always needed 3 Non-technical Areas 3.1 Communicating 3.1.1 The general common points 3.1.2 Eloquence – Speaking Easily the First time 3.1.3 Writing a paper – The basic mechanics help 3.1.5 Listening 3.2 Networking – Becoming an integral part of your field 3.3 Collaborative Research 3.4 Diversity in Science – Being open minded 2.5 Using a mentor – Help Wanted: Sage and Wise Chemists to help guide 3.6 Being a mentor 3.7 Behaviours 3.7.1 Personalities and Styles in Dealing with Others 3.7.2 Dealing with Those on the Dark Side – difficult and worse people 3.7.3 Ethics – The Right Things to Do 3.8 Teams, Teamwork and Leadership 3.9 Balancing professional and private time 4 Career Changes 4.1 The Rewards or working in industry – Starting and choosing a direction from graduate school to an industrial career 4.2 Industry versus academia – The Merits of an Industrial Career in Contacts to one in Academia 4.3 Resume and curriculum vita – Getting the messageacross 4.4 The grass is greener – A Comparison Between Workplaces 4.5 Changing hats – supervising and managing 4.6 Personal skills and assessments 4.7 Degree of difficulty – non-advanced degree chemists 4.8 Pursuit of Non-traditional Careers in Chemistry 5 Bibliography
£71.24
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Biotechnology in China III: Biofuels and Bioenergy
Book SynopsisCellulolytic Enzyme Production and Enzymatic Hydrolysis for Second-Generation Bioethanol Production, by Mingyu Wang, Zhonghai Li, Xu Fang, Lushan Wang und Yinbo Qu Bioethanol from Lignocellulosic Biomass, by Xin-Qing Zhao, Li-Han Zi, Feng-Wu Bai, Hai-Long Lin, Xiao-Ming Hao, Guo-Jun Yue und Nancy W. Y. Ho Biodiesel From Conventional Feedstocks, by Wei Du und De-Hua Liu Establishing Oleaginous Microalgae Research Models for Consolidated Bioprocessing of Solar Energy, by Dongmei Wang, Yandu Lu, He Huang und Jian Xu Biobutanol, by Hongjun Dong, Wenwen Tao, Zongjie Dai, Liejian Yang, Fuyu Gong, Yanping Zhang und Yin Li Branched-Chain Higher Alcohols, by Bao-Wei Wang, Ai-Qin Shi, Ran Tu, Xue-Li Zhang, Qin-Hong Wang und Feng-Wu Bai Advances in Biogas Technology, by Ai-Jie Wang, Wen-Wei Li und Han-Qing Yu Biohydrogen Production from Anaerobic Fermentation, by Ai-Jie Wang, Guang-Li Cao und Wen-Zong Liu Microbial Fuel Cells in Power Generation and Extended Applications, by Wen-Wei Li and Guo-Ping Sheng Fuels and Chemicals from Hemicellulose Sugars, by Xiao-Jun Ji, He Huang, Zhi-Kui Nie, Liang Qu, Qing Xu and George T. TsaoTable of ContentsCellulolytic Enzyme Production and Enzymatic Hydrolysis for Second-Generation Bioethanol Production, by Mingyu Wang, Zhonghai Li, Xu Fang, Lushan Wang und Yinbo Qu.- Bioethanol from Lignocellulosic Biomass, by Xin-Qing Zhao, Li-Han Zi, Feng-Wu Bai, Hai-Long Lin, Xiao-Ming Hao, Guo-Jun Yue und Nancy W. Y. Ho .- Biodiesel From Conventional Feedstocks, by Wei Du und De-Hua Liu.- Establishing Oleaginous Microalgae Research Models for Consolidated Bioprocessing of Solar Energy, by Dongmei Wang, Yandu Lu, He Huang und Jian Xu.- Biobutanol, by Hongjun Dong, Wenwen Tao, Zongjie Dai, Liejian Yang, Fuyu Gong, Yanping Zhang und Yin Li.- Branched-Chain Higher Alcohols, by Bao-Wei Wang, Ai-Qin Shi, Ran Tu, Xue-Li Zhang, Qin-Hong Wang und Feng-Wu Bai.- Advances in Biogas Technology, by Ai-Jie Wang, Wen-Wei Li und Han-Qing Yu.- Biohydrogen Production from Anaerobic Fermentation, by Ai-Jie Wang, Guang-Li Cao und Wen-Zong Liu.- Microbial Fuel Cells in Power Generation and Extended Applications, by Wen-Wei Li and Guo-Ping Sheng.- Fuels and Chemicals from Hemicellulose Sugars, by Xiao-Jun Ji, He Huang, Zhi-Kui Nie, Liang Qu, Qing Xu and George T. Tsao.
£170.99
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Empirische Forschung in den Wirtschafts- und
Book SynopsisDieses Buch vermittelt das erforderliche Hintergrundwissen, das für die erfolgreiche Umsetzung eines empirischen Projektes nötig ist. Neben der grundsätzlichen Diskussion über das Wesen empirischer Forschung werden alle Phasen, die ein Projekt typischerweise durchläuft, abgehandelt: Besonderheiten unterschiedlicher Erhebungsmethoden, eine anwendungsorientierte Darstellung der Stichprobentheorie sowie die umsetzungsorientierte Gestaltung von Fragebögen. Der zweite Teil legt den Fokus auf die statistische Datenanalyse, ohne sich in Formeln zu verlieren. Praktische Umsetzung und Interpretation nehmen diesem – teils gefürchteten – Teil der empirischen Arbeit den Schrecken und machen die Notwendigkeit solider statistischer Analyse deutlich. Die Interpretation erfolgt überwiegend anhand von Outputs, die mit dem Auswertungsprogramm SPSS erzeugt wurden. Im Vordergrund steht aber nicht die technische Durchführung, sondern der kompetente Umgang mit den Ergebnissen. Ob diese mit SPSS oder einem der vielen anderen statistischen Auswertungsprogramme erzeugt werden, ist letztlich nachrangig. Entscheidend ist die Fähigkeit, die Ergebnisse richtig zu interpretieren und darauf aufbauend praxisrelevante Ableitungen zu entwickeln, um das Projekt zu einem erfolgreichen Abschluss zu bringen.Durch die anwendungsorientierte Gestaltung der Fallbeispiele, die sich durch das gesamte Buch ziehen, wird das Verständnis und die Übertragung auf eigene Fragestellungen erleichtert. Reflektionen über ethisch-moralische Aspekte der empirischen Forschung – Stichwort Datenschutz – regen zum kritischen Hinterfragen eigener Projekte an.Table of ContentsEmpirischer Forschungsprozess.- Sekundärerhebung.- Primärerhebung.- Fragebogengestaltung.- Stichprobentheorie.- Grundlagen der Datenanalyse.- Ausgewählte Multivariate Analyseverfahren.
£29.99
£19.43
Springer, India, Private Ltd Plant Tissue Culture: An Introductory Text
Book SynopsisPlant tissue culture (PTC) is basic to all plant biotechnologies and is an exciting area of basic and applied sciences with considerable scope for further research. PTC is also the best approach to demonstrate the totipotency of plant cells, and to exploit it for numerous practical applications. It offers technologies for crop improvement (Haploid and Triploid production, In Vitro Fertilization, Hybrid Embryo Rescue, Variant Selection), clonal propagation (Micropropagation), virus elimination (Shoot Tip Culture), germplasm conservation, production of industrial phytochemicals, and regeneration of plants from genetically manipulated cells by recombinant DNA technology (Genetic Engineering) or cell fusion (Somatic Hybridization and Cybridization). Considerable work is being done to understand the physiology and genetics of in vitro embryogenesis and organogenesis using model systems, especially Arabidopsis and carrot, which is likely to enhance the efficiency of in vitro regeneration protocols. All these aspects are covered extensively in the present book. Since the first book on Plant Tissue Culture by Prof. P.R. White in 1943, several volumes describing different aspects of PTC have been published. Most of these are compilation of invited articles by different experts or proceedings of conferences. More recently, a number of books describing the Methods and Protocols for one or more techniques of PTC have been published which should serve as useful laboratory manuals. The impetus for writing this book was to make available a complete and up-to-date text covering all basic and applied aspects of PTC for the students and early-career researchers of plant sciences and plant / agricultural biotechnology. The book comprises of nineteen chapters profusely illustrated with self-explanatory illustrations. Most of the chapters include well-tested protocols and relevant media compositions that should be helpful in conducting laboratory experiments. For those interested in further details, Suggested Further Reading is given at the end of each chapter, and a Subject and Plant Index is provided at the end of the book.Trade ReviewFrom the reviews:“Bhojwani and Dantu … provide solid background information on and recommendations for establishing plant tissue culture labs, and discuss the theory, development, and recent advances for numerous plant tissue culture applications. … the book describes techniques in considerable detail, and several chapters are supplemented with full protocols. This volume will be particularly useful as an overview of plant tissue culture applications for graduate-level students and professionals new to the field. Summing Up: Recommended. Upper-division undergraduates through professionals.” (R. M. Warner, Choice, Vol. 51 (4), December, 2013)Table of ContentsPreface.- 1. Historical Sketch.- 2. General Requirements and Techniques.-3. Culture Media.- 4.Tissue and Cell Culture.- 5.Cytodifferentiation.- 6. Cellular Totipotency.- 7. Somatic Embryogenesis.- 8. Androgenesis.- 9. Gynogenesis.- 10. Triploid Production.- 11. Zygotic Embryo Culture.- 12. Somaclonal Variation.- 13. In vitro Fertilization.- 14. Parasexual Hybridization.- 15. Genetic Engineering.- 16. Production of Virus-free Plants.- 17. Micropropagation.- 18. Production of Industrial Phytochemicals.- 19. Conservation of Biodiversity.- Subject Index.
£208.99
Springer Yeast Biotechnology: Diversity and Applications
Book SynopsisI belie ve that the book would provide an overview of the recent developments in the domain of yeast research with some new ideas, which could serve as an inspiration and challenge for researchers in this field. Ne w Delhi Prof. Asis Datta Dec. 24, 2007 F ormer Vice-chancellor, JNU Director, NCPGR (New Delhi) Pr eface Yeasts are eukaryotic unicellular microfungi that are widely distributed in the natural environments. Although yeasts are not as ubiquitous as bacteria in the na- ral environments, they have been isolated from terrestrial, aquatic and atmospheric environments. Yeast communities have been found in association with plants, a- mals and insects. Several species of yeasts have also been isolated from specialized or extreme environments like those with low water potential (e. g. high sugar/salt concentrations), low temperature (e. g. yeasts isolated from Antarctica), and low oxygen availability (e. g. intestinal tracts of animals). Around 1500 species of yeasts belonging to over 100 genera have been described so far. It is estimated that only 1% of the extant yeasts on earth have been described till date. Therefore, global efforts are underway to recover new yeast species from a variety of normal and extreme environments. Yeasts play an important role in food chains, and carbon, nitrogen and sulphur cycles. Yeasts can be genetically manipulated by hybridization, mutation, rare m- ing, cytoduction, spheroplast fusion, single chromosomal transfer and transfor- tion using recombinant technology. Yeasts (e. g.Trade ReviewFrom the reviews: “This book updates the knowledge on yeast research and applications accumulated over the last twenty years using the expertise of the various experts in this field. … The editors and authors have produced an excellent up-to date book that will be extremely useful for graduate and post-graduate students, young and senior researchers of life sciences … . should be on the shelves of libraries at universities, research institutes and industry, and is also to be recommended to all those who are interested in life sciences.” (Uta Breuer, Biotechnology Journal, Vol. 5, 2010)Table of Contents1 Antarctic yeasts: biodiversity and potential applications, S. Shivaji and G. S. Prasad; 2 Basidiomycetous yeasts: Current status, B.N. Johri and D.K. Choudhury; 3 Hansenula polymorpha (Pichia angusta) - Biology and applications, Gotthard Kunze, Hyun Ah Kang and Gerd Gellissen; 4 Debaryomyces hansenii: an osmotolerant and halo-tolerant yeast, Monika Aggarwal and Alok K Mondal; 5 Candida famata (Debaryomyces hansenii), Andriy A. Sibirny and Andriy Y. Voronovsky; 6 Pichia guilliermondii, Andriy A. Sibirny and Yuriy R. Boretsky; 7 Assimilation of unusual carbon compounds, Wouter J. Middelhoven; 8 Ecology and biodiversity of yeasts with potential value in biotechnology, T. Deak; 9 Yeast diversity in fermented foods and beverages, Jyoti Prakash Tamang and Graham H. Fleet; 10 Utilization of yeasts in biological control programs, Pimenta, R.S., Morais, P.B., Rosa, C.A. and Corrêa Jr., A.; 11 Opportunistic pathogenic yeasts, Uma Banerjee; 12 Interaction between yeasts and zinc, Raffaele De Nicola and Graeme Walker; 13 Glutathione production in yeast, Anand K Bachhawat, Dwaipayan Ganguli, Jaspreet Kaur, Neha Kasturia, Anil Thakur, Hardeep Kaur, Akhilesh Kumar and Amit Yadav; 14 Fermentative and aromatic ability of Kloeckera and Hanseniaspora yeasts, Dulce M. Díaz-Montaño and J. de Jesús Ramírez Córdova; 15 Assimilatory nitrate reduction in Hansenula polymorpha, Beatrice Rossi and Enrico Berardi; Part II. Genetic and Molecular Insights:16 Yeast genetics and biotechnological applications, Saroj Mishra and Richa Singh; 17 A wide-range integrative expression vector (comedtm) system for yeasts, Gerhard Steinborn, Gotthard Kunze and Gerd Gellissen; 18 Advances in gene expression in non-conventional yeasts, Jacobus Albertyn, Michel Labuschagne and Sanet Nel; 19 A comparative study of RNApolymerase II transcription machinery in yeasts, Nimisha Sharma and Surbhi Mehta; 20 Non-genetic engineering approaches to isolating and generating novel yeasts for industrial applications, Paul J. Chambers, Jenny R. Bellon, Simon A. Schmidt, C. Varela and Isak S. Pretorius; 21 Yeast proteome analysis, Andrea Matros and Hans-Peter Mock; 22 Yeast genomics for bread, beer, biology, bucks and breath, Kishore R. Sakharkar and Meena K. Sakharkar; Part III. Biotechnological Applications: 23 Ethanol production from traditional and emerging raw materials, Andreas Rudolf, Kaisa Karhumaa and Bärbel Hahn-Hägerdal; 24 Potentiality of yeasts in the direct conversion of starchy materials to ethanol and its relevance in the new millennium, L.V.A.Reddy, O.V.S.Reddy and S.C. Basappa; 25 Thermotolerant yeasts for bioethanol production using ignocellulosic substrates, L.Venkateswar Rao and Chand Pasha; 26 Applications of the non-conventional yeast Yarrowia lipolytica, France Thevenieau, Jean-Marc Nicaud and Claude Gaillardin; 27 Arxula adeninivorans (Blastobotrys adeninivorans) – a dimorphic yeast of great biotechnological potential, Erik Böer, Gerhard Steinborn, Kristina Tag, Martina Körner, Gerd Gellissen and G. Kunze; 28 Biotechnological applications of dimorphic yeasts, N. Doiphode, C. Joshi, V. Ghormade and M.V. Deshpande; 29 Extracellular polysaccharides produced by yeasts and yeast-like fungi, Inge N.A. Van Bogaert, Sofie L. De Maeseneire and Erick J. Vandamme; 30 Industrially important carbohydrate degrading enzymes from yeasts: pectinase and chitinase, ß-1, 3-glucanase, Sathyanarayana N. Gummadi, D. Sunil Kumar, Swati S. Dash and Santosh Kumar Sahu; 31 Yeast acid phosphatases and phytases: production, characterization and commercial prospects, Kaur, P. and T. Satyanarayana; 32 Nitrile-metabolizing yeasts, Tek Chand Bhalla, Monica Sharma and
£237.49
£17.10
Astral International Pvt Ltd Envoinformatics
Book Synopsis
£63.00
Astral International Biotechnological Tools for Genetic Resources
£66.50
Astral International Pvt Ltd Handbook on Dairy Chemistry For B.Sc. Dairy Chemistry as per ICAR Syllabus Edition1st
£84.68
Astral International Pvt Ltd ImmunologyInt
£77.91
Astral International Pvt Ltd Emerging Pattern in Plant Genomics and Marker Assisted Breeding Volume IIInt
£47.50
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