Medical specialties, branches of medicine Books

Book SynopsisThe ABC of Sports and Exercise Medicine provides general practitioners with a comprehensive overview of the field of sports medicine.Table of ContentsList of Contributors vii Part I Injury 1 Epidemiology of Sports Injuries and Illnesses 1 Debbie Palmer-Green 2 Immediate Care in Sport 5 Andy Smith 3 Head Injuries in Sport 10 Daniel G. Healy 4 Injury of the Face and Jaw 21 Keith R. Postlethwaite 5 Eye Injuries in Sport 26 Caroline J. MacEwen 6 Management of Injuries in Children 31 Julian Redhead 7 Management of Musculoskeletal Injuries in the Mature Athlete 38 Khan Karim and Peter D. Brukner 8 Medical Care at Major Sporting Events, 41 Mike Loosemore Part II System Sport and Exercise Medicine 9 Pulmonary Dysfunction in Athletes 44 John Dickinson and James Hull 10 Infections 50 Michael J. Martin 11 The Unexplained Underperformance Syndrome (Overtraining Syndrome), 54 Richard Budgett and Yorck Olaf Schumacher 12 The Female Athlete Triad 58 Noel Pollock 13 The Athlete’s Heart 62 Aneil Malhotra, Greg P. Whyte and Sanjay Sharma Part III Environmental Sport and Exercise Medicine 14 Extreme Temperature Sport and Exercise Medicine 67 Michael J. Tipton 15 Diving Medicine 76 Peter T. Wilmshurst 16 Altitude Medicine 81 Sundeep Dhillon Part IV Special Populations 17 Physical Activity and Exercise as Medicine 86 John Buckley 18 Sport, Exercise and Disability 89 Nick Webborn 19 Sport, Exercise and Obesity 93 David Haslam 20 Sport and Children 97 Neil Armstrong 21 Physical Activity and Exercise in Later Life 102 Dawn A. Skelton and Finbarr C. Martin Part V Nutrition and Doping 22 Nutrition, Energy Metabolism and Ergogenic Supplements 109 Clyde Williams 23 Drugs in Sport 116 Roger Palfreeman 24 Psychology of Injury 122 Andrew M. Lane Index 127

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Book SynopsisEarly Years Nutrition and Healthy Weight focuses on the early years of childhood as a key period in which eating and exercise habits are formed. Combining current evidence with practical advice, an international group of health specialists advise on the avoidance and management of childhood obesity.Table of ContentsContributors, viii Foreword, x Acknowledgments, xii 1 Importance of good health and nutrition before and during pregnancy, 1Catherine R. Hankey 2 Nutrition and health in the early years, 14Judy More 3 Defining and measuring childhood obesity, 30Charlotte M. Wright 4 Early life risk factors for childhood obesity, 40John J. Reilly and Adrienne R. Hughes 5 Early physical activity and sedentary behaviours, 46Anthony D. Okely and Xanne Janssen 6 Talking about weight with families, 59Paul Chadwick and Helen Croker 7 Parenting strategies for healthy weight in childhood, 71Clare Collins, Tracy Burrows and Kerith Duncanson 8 Pre-school prevention interventions, 81Pinki Sahota 9 Contribution of food provision in primary schools to the prevention of childhood obesity, 91Ethan A. Bergman 10 Early clinical interventions and outcomes, 100Louise A. Baur Index, 112

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Book SynopsisReview Questions for Dentistry is an essential exam practice tool designed for undergraduate dentistry students, postgraduate MJDF candidates, and overseas candidates sitting their OREs.Table of ContentsAbout the companion website, vii Introduction: How to approach answering multiple choice questions, ix Section 1: Questions testing the introductory aspects of the subject 1 Endodontics, 3 2 Periodontology, 11 3 Operative dentistry, 19 4 Prosthodontics, 25 5 Medical and surgical aspects of oral and dental health, 33 6 Paediatric dentistry, public dental health and orthodontics, 40 Section 2: Questions exploring the subjects in more detail 7 Endodontics, 51 8 Periodontology, 75 9 Operative dentistry, 97 10 Prosthodontics, 118 11 Medical and surgical aspects of oral and dental health, 153 12 Paediatric dentistry, public dental health and orthodontics, 171 Further reading, 176 Index, 183

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Book SynopsisNeonatal Formulary is a unique publication that provides comprehensive guidance on the safe use of all the drugs prescribed during pregnancy and commonly given to babies during labour, delivery, and the first year of life. This new editionprovides improved and detailed coverage of the many drugs that are given to women during pregnancy and during lactation where the baby''s welfare must be borne in mind as well as that of the mother. Thus the whole ''pregnancy through to parenthood'' journey is treated as a continuous event with information about drug use and the effects of drugs at all stages of the development from fetus to infant. Containing far more detail than is available in the British National Formulary for Children and with a companion website featuring updates related to specific drugs and dosing, Neonatal Formulary is an essential guide for neonatologists, neonatal nurses, hospital pharmacists, obstetric staff, advanced nurse practitioners and Table of ContentsIntroduction viii Important advisory statement xi Further reading xiii Acknowledgements xv Part 1: Drug prescribing and drug administration 1 Terms, symbols, abbreviations and units 3 Drug storage and administration 5 Drugs and the body 12 Drugs and the law 14 The care and use of intravascular lines 17 Minimising IV infusion and other drug hazards 24 Patient safety initiatives 27 Writing a hospital prescription 30 Adverse reactions and overtreatment 33 Maternal drug abuse 36 Renal failure 39 Body weight and surface area 42 Effects of therapeutic hypothermia on medications 44 Useful websites 48 Part 2: Drug monographs 55 Part 3: Maternal medication and its effect on the baby 555 Introduction 556 Further reading 558 Maternal medication and the baby 560 Index 608

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Book SynopsisTable of ContentsAbbreviations ix Contributors xi Preface xv First Foreword xvii Second Foreword xix Part I Basic Principles 1 1. Basic Urodynamics and Fundamental Issues 3Marcus Drake, Andrew Gammie, Laura Thomas, Arturo García-Mora, and Hashim Hashim 2. Applied Anatomy and Physiology 24Chendrimada Madhu and Marcus Drake 3. The Physics of Urodynamic Measurements 45Andrew Gammie Part II Functional Urology 53 4. Patient Assessment 55Musaab Yassin, Alan Uren, and Nikki Cotterill 5. Treatments for Lower Urinary Tract Dysfunction 73Sharon Yeo and Hashim Hashim Part III Urodynamic Techniques 93 6. Uroflowmetry 95Amit Mevcha and Richard Napier-Hemy 7. Cystometry and Pressure-Flow Studies 109Marcus Drake, Rachel Tindle, and Su-Min Lee 8. Video Urodynamics 158Marcus Drake, Michelle Ong, Devang Desai, Michel Wyndaele, Mark Woodward, and Hashim Hashim 9. Ambulatory Urodynamics 193Julie Ellis-Jones and Wendy Bevan 10. Studies Assessing Urethral Pressures 199Dharmesh Kapoor and Marcus Drake 11. Non-invasive Urodynamics 217Alison Bray, Christopher Blake, and Christopher Harding Part IV Urodynamics in Clinical Practice 227 12. Urodynamics in Children 229Jonathan S. Ellison, Guy Nicholls, and Mark Woodward 13. Urodynamics in Women 242Wael Agur, Ruben Trochez, Antonin Prouza, George Kasyan, and Abdelmageed Abdelrahman 14. Urodynamics in Men 273Arturo García-Mora, Connie Chew, and Marcus Drake 15. Structural Changes of the Bladder Outlet 301Michelle Ong, Marcus Drake, and Devang Desai 16. Neurological Disease and LUTS 313Marcus Drake, Jeremy Nettleton, and Mohammed Belal 17. Urodynamics in Older People 360Su-Min Lee and Emily Henderson Part V Running a Urodynamics Unit 369 18. Troubleshooting During Urodynamics 371Laura Thomas, Rachel Tindle, and Andrew Gammie 19. Artefacts in Urodynamics 383Andrew Gammie 20. Anorectal Physiology 394Laura Thomas and Kathryn McCarthy 21. Organisation of the Urodynamic Unit 406Laura Thomas, Alexandra Bacon, Joanne Sheen, and Andrew Gammie 22. Equipment 412Andrew Gammie 23. Working with Limited Resources 415Andrew Gammie, Laura Thomas, Marcus Drake, and Eskinder Solomon 24. Research Evidence on the Clinical Role of Urodynamics 420Andrew Gammie, Marcus Drake, and Hashim Hashim Appendices Key Patient Assessment Tools from the International Consultation on Incontinence Questionnaires (ICIQ) 423 ICIQ-FLUTS 423 ICIQ-MLUTS 427 ICIQ-BD 432 Fundamentals Documents from the International Continence Society 434 N&U 2018 Volume 37 Supplement 6 434 Editorial Comment 439 A Commentary on Expectations of Healthcare Professionals When Applying the International Continence Society Standards to Basic Assessment of Lower Urinary Tract Function 440 Fundamentals of Terminology in Lower Urinary Tract Function 446 Basic Concepts in Nocturia, Based on International Continence Society Standards in Nocturnal Lower Urinary Tract Function 453 Neurological Lower Urinary Tract Dysfunction Essential Terminology 458 The Fundamentals of Chronic Pelvic Pain Assessment, Based on International Continence Society Recommendations 465 How to Use the Pelvic Organ Prolapse Quantification (POP-Q) system? 472 The Fundamentals of Uroflowmetry Practice, Based on International Continence Society Good Urodynamic Practices Recommendations 477 Fundamentals of Urodynamic Practice, Based on International Continence Society Good Urodynamic Practices Recommendations 483 Basics of Videourodynamics for Adult Patients With Lower Urinary Tract Dysfunction 494 Why ICS Standardization of Lower Urinary Tract Symptoms Matters 500 Critical Steps in Developing Professional Standards for the International Continence Society 502 Patient Information Leaflets from the Bristol Urological Institute 508 Free Flow Rate Testing 508 Urodynamics 515 Practice, Standards, and Equipment Recommendations 530 International Consultation on Incontinence 2016; Executive Summary: Urodynamic Testing 531 United Kingdom Continence Society: Minimum Standards for Urodynamic Studies, 2018 539 UK Centre for Evidence-Based Purchasing; Buyers’ Guide Urodynamics Systems 571 International Continence Society Good Urodynamic Practices and Terms 2016: Urodynamics, uroflowmertry, cystometry, and pressure-flow study 578 Good Urodynamic Practices Documents from the International Continence Society 595 Good Urodynamic Practices: Uroflowmetry, Filling Cystometry, and Pressure-Flow Studies 596 Index 610

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Book SynopsisThis book focuses on educating radiologists, radiation oncologists and others interested in imaging research about how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers.Table of ContentsContributors, vi Chapter 1 Imaging technology assessment, 1Pari V. Pandharipande and G. Scott Gazelle Chapter 2 Clinical trials of therapy, 10Sayeh Lavasani, Anthony F. Shields and Ali Mahinbakht Chapter 3 Clinical trials of image]guided interventions including radiotherapy studies, 29Gary S. Dorfman and Stephen M. Hahn Chapter 4 Imaging as a predictor of therapeutic response, 57David A. Mankoff and Anthony F. Shields Chapter 5 Screening trials and design, 76Janie M. Lee, Constance D. Lehman and Diana L. Miglioretti Chapter 6 Practicalities of running a clinical trial, 91Michael T. Lu, Elizabeth C. Adami and Udo Hoffmann Chapter 7 Statistical issues in study design, 103Nancy A. Obuchowski Chapter 8 Introduction to biostatistical methods, 126Diana L. Miglioretti, Todd A. Alonzo and Nancy A. Obuchowski Chapter 9 Methods for studies of diagnostic tests, 147Jeffrey D. Blume Chapter 10 Methods for quantitative imaging biomarker studies, 170Alicia Y. Toledano and Nancy A. Obuchowski Chapter 11 Introduction to cost]effectiveness analysis in clinical trials, 189Ruth C. Carlos and G. Scott Gazelle Index, 208

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Book SynopsisBlandy''s Urology, 3rd edition is set to become a classic in its field, the latest edition of one of the most well-loved general urology textbooks for urologists and surgeons alike, successfully combining both general urology and urologic surgery. Its key strength is the unique Blandy way' of describing urological diseases and their management, consisting of: clear, straightforward, uncomplicated descriptions of disease/conditions, includinghundreds ofclinical photos an abundance of outstanding drawn surgical diagrams to illustrate best technique in the operating theatre a focus on the most commonly seen problems in the clinic organization of each topic underanatomical headings Especially loved by urology and surgery trainees for its straightforward approach to the speciality and as a preparation for speciality urology exams, consultants and specialists also value it as a handy refresher tool.Table of ContentsPreface xxxvii List of Contributors xxxix Part I 1 1 Armaments in Urology 3Shibs Datta 1.1 Principles of Urological Technology 4 1.2 Wound Healing in the Urinary Tract 19 1.3 Simulation in Urology 27 2 Principles of Medical Statistics 39Julie Morris 2.1 Introduction 39 2.2 Descriptive Statistics 39 2.3 Confidence Intervals 41 2.4 Significance Tests 42 2.5 Relationships between Variables 44 2.6 Diagnostic Tests 45 2.7 Study Design 46 2.8 Number Needed to Treat 47 2.9 Systematic Reviews and Meta‐Analysis 47 3 Embryology for the Urologist 49Allan Johnston, Maike F. Eylert, Tarik Amer, and Omar M. Aboumarzouk 3.1 Historical Consideration 50 3.2 Introduction 50 3.3 Embryology of the Kidneys and Ureters 50 3.4 Embryology of the Bladder 57 3.5 Embryology of the Indifferent Genital System 60 3.6 Embryology of the Male Genital System 61 3.7 Embryology of the Prostate 67 3.8 Embryology of the Penis and Urethra 68 3.9 Neuter State 70 3.10 Embryology of the Female Genital System 70 3.11 Embryology of the Adrenal Gland 71 References 4 Principles of Urologic Oncology 75Oliver W. Hakenberg 4.1 The Scope of Urologic Oncology 75 4.2 Carcinogenesis 75 4.3 Molecular Biology of Cancer Growth 79 4.4 Tumour‐ Promoting Inflammation 81 4.5 Reprogramming Energy Metabolism 81 4.6 Evading Immune Destruction 82 4.7 The Tumour Microenvironment 82 4.8 The Rate of Cancer Growth 82 4.9 Principles of Treatment 82 4.10 Oncologic Surgery 84 Part II 91 5 Kidney and Ureter Anatomy 93Hiro Ishii, Omar M. Aboumarzouk, and Hendrik Van Poppel 5.1 Comparative Anatomy 94 5.2 Renal Fasciae 96 5.3 Macroscopic Appearances 96 5.4 Arterial Supply 96 5.5 Renal Veins 98 5.6 Common Vascular and Anatomic Variations 99 5.7 Lymphatics 99 5.8 Innervation of the Kidney 99 6 Kidney and Ureter Physiology 107Motaz ElMahdy Hassan and Mohamed Ismail 6.1 Glomerular Filtration Rate 107 6.2 Renal Tubules 109 6.3 Hormonal Function of the Kidney 110 6.4 Special Disorders of Renal Tubules 111 6.5 Acid–Base Metabolism 111 6.6 Obstructive Uropathy 112 6.7 Ureteric Physiology 113 6.8 Whitaker Test 114 7 Renal Failure 117Pramod Nagaraja and Farid Ghalli 7.1 Acute Kidney Injury 117 7.2 Chronic Kidney Disease 120 7.3 Dialysis 123 8 Renal Transplant 127Oliver W. Hakenberg 8.1 The Patients and the Kidneys 128 8.2 Technique of Removal of Donor Kidneys 130 8.3 Immunology of Organ Transplantation 137 8.4 Graft Rejection 139 8.5 Immunosuppression 141 9 Kidney and Ureter: Congenital and Acquired Anomalies 145Alberto Mantovani, Jane Hendry, and Pankaj Mishra 9.1 Introduction 145 9.2 Congenital Abnormalities of the Kidney 145 9.3 Congenital Abnormalities of the PUJ 153 10 Hydronephrosis 165Maitrey Darrad, Ameet Gupta, and Nick Rukin 10.1 Definition 165 10.2 Incidence 165 10.3 Pathophysiology 166 10.4 Diagnostic Imaging 169 10.5 Complications of Hydronephrosis 171 10.6 Management (General Principles) 171 10.7 Perinatal Hydronephrosis 171 10.8 Pelviureteric Junction Obstruction 172 10.9 Retrocaval Ureter 181 10.10 Duplication Anomalies, Ectopic Ureter, and Ureteroceles 181 10.11 VUR 183 10.12 Megaureter 185 10.13 Ureteral Strictures 185 11 Kidney and Ureter Trauma 189Sarfraz Ahmad and Omar M. Aboumarzouk 11.1 Kidney Injuries 189 11.2 Ureteral Injuries 200 12 Kidney and Ureter Inflammation 209Ameet Gupta and Krishna Narahari 12.1 Medical Inflammatory Conditions of the Kidney 209 12.2 Acute Surgical Inflammatory Conditions of the Kidney 211 12.3 Chronic Surgical Inflammatory Conditions of the Kidney 218 12.4 Other Inflammatory Conditions of the Kidney 223 12.5 Inflammatory Conditions of the Ureters 228 13 Kidney and Ureter Neoplasm 237Jane Hendry, Bhavan P. Rai, Alan S. McNeill, Ghulam Nabi, Jens-Uwe Stolzenburg, Khaver Qureshi, Nkem Umez‐Eronini, Grenville Oades, and Omar M. Aboumarzouk 13.1 Kidney Neoplasms 238 13.2 Benign Renal Masses 258 13.3 Ureter and Renal Pelvis Neoplasms 261 14 Kidney and Ureter Calculi 277Omar M. Aboumarzouk, Paul Cook, Olivier Traxer, Palle J.S. Osther, Luca Villa, Jonathan Cloutier, Helene Jung, Kim H. Andreassen, and Bhaskar K. Somani 14.1 Epidemiology 277 14.2 Pathophysiology 277 14.3 Formation of Calculi in the Kidney 278 14.4 Common Types of Urinary Stones 279 14.5 Clinical Features 281 14.6 Complications of Stones 281 14.7 Investigations 282 14.8 Investigations for Metabolic Stone Disease 288 14.9 Medical Management of Stones 289 14.10 Surgery for Stones 291 15 Kidney and Ureter Vascular Disorders 321Abdullah Zreik and Omar M. Aboumarzouk 15.1 Congenital Anomalies of the Renal Vessels 321 15.2 Renal Artery Disorders 322 15.3 Disorders of the Renal Veins 328 16 The Adrenal Glands 331Michael Stechman and David Scott Coombes 16.1 Principles of Endocrine Surgery 331 16.2 Anatomy 332 16.3 Physiology 333 16.4 Pathology 334 16.5 Pathology of the Adrenal Medulla 340 16.6 Congenital Disorders of the Adrenals 346 16.7 Trauma 346 16.8 Inflammation 346 Part III 349 17 Bladder and Urethra Structure and Function 351Maike F. Eylert and Arjun K. Nambiar 17.1 Anatomy 351 17.2 Physiology 355 18 Bladder Congenital Anomalies 359Katerina Prodromou and Pankaj Mishra 18.1 Embryology 359 18.2 Exstrophy‐ Epispadias Complex 359 18.3 Urachal Anomalies 368 18.4 Bladder Diverticula 370 18.5 Disorders of Development of the Sacrum 371 18.6 UTI in Children 371 19 Bladder Trauma 383Abdullah Zreik, Ahmed Mahrous, and Omar M. Aboumarzouk 19.1 Bladder Injuries 383 20 Bladder Inflammation 391Ameet Gupta, Anna Manwaring, and Krishna Narahari 20.1 Introduction and Definitions 391 20.2 Acute Cystitis or Lower UTI 392 20.3 Chronic Interstitial Cystitis and Bladder Pain Syndrome 400 20.4 Tuberculosis 400 20.5 Parasitic Infections 400 20.6 Amoebiasis 405 20.7 Worm Infestations 406 20.8 Catfish 406 21 Bladder Neoplasm 409Kawa Omar, Nawal Shamim Khan, and Muhammad Shamim Khan 21.1 Bladder Neoplasm 410 21.2 Field Biopsies 417 21.3 Pathology 417 21.4 Malignant Tumours of the Bladder 417 21.5 Grading of Transitional Cell Carcinoma 422 21.6 Staging of Bladder Tumours 422 21.7 Risk Stratification after Transurethral Resection of Bladder Tumour 422 21.8 Treatment of Transitional Cell Carcinoma 422 21.9 Muscle‐ Invasive Bladder Cancer 427 21.10 Recurrence and Follow‐up of MIBC 435 21.11 Management of Locally Advanced MIBC (T3b/T4) and Metastatic Disease (N1 or M1) 435 21.12 Bladder Cancer Variants 437 22 Urinary Diversion 447Kawa Omar, Nawal Shamim Khan, Shahrokh F. Shariat, Johannes Alfred Witjes, and Muhammad Shamim Khan 22.1 Urinary Diversions 448 22.2 Bladder Urinary Diversion 449 22.3 Functional Follow‐Up 461 22.4 Quality of Life Urinary Diversion after Cystectomy 461 23 Bladder Disorder of Function 465Arjun K. Nambiar, Maike F. Eylert, Lisette A ‘t Hoen, and Bertil F.M. Blok 23.1 Introduction 465 23.2 Investigating Bladder Function 468 23.3 Disorders of Function 476 23.4 Urethral Disorders 489 24 Fistulae and Sinuses 499Jenny Jones and Omar M. Aboumarzouk 24.1 Principles and Definitions 499 24.2 Pathophysiology 499 24.3 General Complications 500 24.4 Organ‐Specific Fistulae 500 Part IV 509 25 Prostate Structure and Function 511Adam Cox, Matthew Jefferies, and Raj Persad 25.1 Comparative Anatomy 511 25.2 Maturation of the Prostate 511 25.3 Anatomy of the Prostate 513 25.4 Prostate Physiology 517 26 Prostate Inflammation 523Mark J. Salji, Truls E. Bjerklund Johansen, and Hing Y. Leung 26.1 Classification of Prostatitis 523 26.2 Investigations 525 26.3 Imaging 525 26.4 Serum Prostate Specific Antigen 526 26.5 Histology 526 26.6 Treatment Options 526 26.7 Upoint Phenotypic Classification of CP/CPPS 527 26.8 Surgical Options 527 26.9 Heat Therapies 527 26.10 Prostate Tuberculosis 528 26.11 Summary 528 27 Prostate Benign Prostatic Hyperplasia 531Daniel W. Good, Bashar Nahas, Simon Phipps, Rick Popert, Jens‐Uwe Stolzenburg, and Stuart Alan S. McNeill 27.1 Nomenclature 532 27.2 Aetiology 532 27.3 Pathology of BPH 534 27.4 Complications of BPH 535 27.5 Epidemiology and Natural History of BPH 538 27.6 Investigations 539 27.7 Management 541 27.8 Surgical Management 547 28 Prostate Neoplasm 563Mark J. Salji, Imran Ahmad, Sarah Slater, Fat‐Wui Poon, Abdulla Alhasso, Nadja V. Melquiot, Holly Bekarma, Jane Hendry, and Hing Y. Leung 28.1 Epidemiology 563 28.2 Aetiology 564 28.3 Clinical Features 565 28.4 Prognosis 566 28.5 Investigations 566 28.6 Pathology, Histopathology, and Molecular Pathology 573 28.7 Management, Treatments, and Patient Selection 577 28.8 Androgen‐Deprivation Therapy 587 28.9 Castration‐Resistant Prostate Cancer 591 28.10 The Role of TURP for Voiding Symptoms Associated with PCa 593 28.11 Controversies, Cutting‐Edge Developments, and Hot Topics 594 Part V 611 29 Penis and Urethra Structure and Penis 613Ayman Younis and Christopher Harding 29.1 Anatomy and Physiology 613 29.2 The Penis 613 29.3 The Scrotum 617 29.4 The Urethra 617 29.5 Erection 619 29.6 Function of the Scrotum 622 30 Penis and Urethra and Prostate Congenital Anomalies 623Anand Upasani, Divyesh Desai, Imran Mushtaq, and Pankaj Mishra 30.1 Foreskin 623 30.2 Hypospadias 628 30.3 Primary Epispadias 632 30.4 Posterior Urethral Valves 635 30.5 Prostatic Utricle 639 30.6 Syringocele 639 30.7 Anterior Urethral Valves 640 30.8 Urethral Duplication 641 30.9 Urethral Anomalies in Anorectal Malformations 642 30.10 Interesting Terminologies 645 31 Penis and Urethra Trauma 651Ayman Younis and Trevor J. Dorkin 31.1 Penis and Scrotum 651 31.2 Urethral Trauma 653 32 Penis and Urethra Inflammation 663Nick Watkin and Asheesh Kaul 32.1 Urethral Inflammation 663 32.2 Penile Inflammation 664 32.3 Other Urethro‐Peno‐Scrotal Pathologies 666 32.4 Stricture Disease of the Urethra 668 32.5 Pelvic Fracture Urethral Injury 676 33 Penis and Urethra Neoplasm 687Tom Swallow and Duncan Summerton 33.1 Penile Neoplasm 687 33.2 Lymph Node Disease 695 33.3 Urethral Neoplasm 699 34 Penis and Urethra Disorders of Function 705Sarfraz Ahmad and Nick Watkin 34.1 Erectile Dysfunction 705 34.2 Premature Ejaculation 712 34.3 Retrograde Ejaculation 715 34.4 Anejaculation 715 34.5 Priapism 716 34.6 Peyronie Disease 719 34.7 Late Onset Hypogonadism 722 Part VI 729 35 Testes Structure and Function 731Tusshyenthan Seevagan, Stephen Hulligan, Jaspal Phull, and Omar M. Aboumarzouk 35.1 Comparative Anatomy 731 35.2 Topographical Anatomy 732 35.3 Blood Supply and Lymphatic Drainage 733 35.4 Epididymis 734 35.5 Vas Deferens 735 35.6 Seminal Vesicle 736 35.7 Verumontanum 736 35.8 Spermatic Cord 736 35.9 Testicular Physiology 736 36 Testes Congenital and Childhood Anomalies 741Eleni Papageorgiou, Abraham Cherian, and Pankaj Mishra 36.1 Congenital Anomalies of the Testis 741 36.2 Inguinoscrotal Masses 749 36.3 The Acute Scrotum 753 37 Testes Trauma and Inflammation 759Senthy Sellaturay, Kamran Ahmed, Muhammad Shamim Khan, and Majed Shabbir 37.1 Testicular Trauma 760 37.2 Inflammatory Diseases of the Testicle 761 37.3 Chronic Inflammation 763 37.4 Treatment 764 38 Testes Benign Swelling 769Jasper Bondad, Piotr L. Chlosta, and Omar M. Aboumarzouk 38.1 Hydrocele 769 38.2 Epididymal Cyst 773 38.3 Benign Testicular Cyst 774 38.4 Testicular Torsion 774 38.5 Polyorchidism 775 38.6 Varicocele 776 38.7 Orchialgia 778 38.8 Nux Amatoris 778 39 Testes Neoplasm 783Michelle Carey, Omar M. Aboumarzouk, and Johannes Alfred Witjes 39.1 History 784 39.2 Incidence 784 39.3 Basic Embryology 784 39.4 Aetiology and Risk Factors 784 39.5 Clinical Features 785 39.6 Diagnosis 785 39.7 Staging 791 39.8 Method of Spread 791 39.9 Prognosis 793 39.10 Treatment 793 39.11 Nongerm Cell Tumours 797 39.12 Tumours Containing Both Germ Cell and Sex Cord or Gonadal Stromal Elements: Gonadoblastoma 798 39.13 Other Tumours of the Testis 798 39.14 Tumours of the Paratesticular Structures 798 40 Male Infertility 803Amr Abdel Raheem, Rowland Rees, and David Ralph 40.1 Incidence 803 40.2 Definitions 803 40.3 History and Examination 804 40.4 Aetiology 804 40.5 Investigations for Male Infertility 807 40.6 Testis Biopsy 809 40.7 Treatment of Male Infertility 811 40.8 Assisted Conception Techniques 812 40.9 Varicocele Repair 812 40.10 Medical Treatment of Male Infertility 813 41 Vasectomy and Seminal Vesicle Disorders 817Omar M. Aboumarzouk, Bryan Jenkins, and Piotr L. Chlosta 41.1 Seminal Vesicles 818 41.2 Vasectomy 820 Index 825

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Book SynopsisA very well written introductory dermatology text with excellent clinical photographs and diagrams. We would highly recommend this for those wishing to grasp the basic concepts in dermatology.British Journal of Dermatology Dermatology Lecture Notes presents an accessible overview of skin structure and function, along with the practical aspects of disease management. Now in its 11th edition, it has been thoroughly updated to focus on recent advances in the knowledge of skin diseases and their treatment. It combines readability with high quality illustrations, and is the ideal guide for new comers to the specialty as well as those more advanced in their studies. Key features include: An overview of the basics of skin structure and function, as well as practical aspects of disease management Excellent clinical photographs, diagrams and histological images Newly expanded and updated sections on benign skin tumours, Table of ContentsPreface vi Acknowledgements vii About the companion website viii 1 Structure and function of the skin hair and nails 1 2 Approach to the diagnosis of dermatological disease 10 3 Emergency dermatology 20 4 Bacterial and viral infections 24 5 Fungal infections 35 6 Ectoparasite infections 44 7 Acne acneiform eruptions and rosacea 54 8 Eczema 63 9 Psoriasis 73 10 Benign and malignant skin tumours 83 11 Naevi 99 12 Inherited disorders 106 13 Pigmentary disorders 114 14 Disorders of the hair and nails 119 15 Bullous disorders 127 16 Miscellaneous erythematous and papulosquamous disorders and light‐induced skin diseases 137 17 Vascular disorders 149 18 Connective tissue diseases 156 19 Pruritus 164 20 Systemic disease and the skin 169 21 Skin and the psyche 178 22 Cutaneous drug reactions 183 23 Treatment of skin disease 189 Glossary of dermatological terms 197 Index 202

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Book SynopsisThe Frith Prescribing Guidelines for People with Intellectual Disability provides comprehensive guidance on prescribing for patients with intellectual disability, as well as general information on the clinical care of this important population. The guidelines have been conceived and developed by clinicians working in intellectual disability services. They are based on both the latest evidence and expert opinion to provide a consensus approach to prescribing as part of a holistic package of care, and include numerous case examples and scenarios. New to this edition are improved coverage of children and the role of primary care teams. The Frith Prescribing Guidelines for People with Intellectual Disability, Third Edition, is a practical guide for busy clinicians, as well as a valuable reference for all primary and secondary health care professionals caring for people with intellectual disability.Table of ContentsList of contributors vii Foreword xi Preface xiii Acknowledgements xv 1 Intellectual Disability 1David Branford and Sabyasachi Bhaumik 2 Prescribing Practice 11David Branford and Sabyasachi Bhaumik 3 Physical and Health Monitoring 21David Branford and Sabyasachi Bhaumik 4 Epilepsy 31Reza Kiani 5 Dementia in People with Intellectual Disability 63Satheesh Kumar Gangadharan and Amala Jesu 6 Eating and Drinking Difficulties 77Jenny Worsfold, Nicky Calow and David Branford 7 Sleep Disorders 95Reza Kiani 8 Women’s Health Issues 107Nyunt Nyunt Tin and Julia Middleton 9 Sexual Offending 117John Devapriam, Pancho Ghatak, Sabyasachi Bhaumik, David Branford, Mary Barrett and Sayeed Khan 10 Autism Spectrum Disorders 125Mary Barrett and Elspeth Bradley 11 Attention Deficit Hyperactivity Disorder 135Karen Bretherton 12 Aggressive Behaviour 147David Branford and Sabyasachi Bhaumik 13 Self]Injurious Behaviour 153Asit Biswas and Sabyasachi Bhaumik 14 Anxiety Disorders 161Avinash Hiremath, Sabyasachi Bhaumik and Khalid Nawab 15 Depression 169Avinash Hiremath, Shweta Gangavati and Mary Barrett 16 Bipolar Affective Disorder 179Desari Mohan Michael, David Branford and Mary Barrett 17 Schizophrenia 193Avinash Hiremath, Amala Jesu and Saduf Riaz 18 Alcohol Use Disorders 203Helen Miller 19 Personality Disorders 215Regi Alexander and Sabyasachi Bhaumik 20 Discussion Case Studies with Suggested Answers 225 Appendix: Summary of Syndromes Mentioned in the Guidelines 241 Index 000

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Book SynopsisThis book is an updated edition of the classic textbook on couple and family therapy through a psychiatric lens. It delineates clinical practice, research, and training issues, in part through case examples. The book presents family therapy and family-oriented interventions with an emerging evidence-base in an easy-to-read and digestible manner.Table of ContentsForewords xixEllen M. Berman MD, Lloyd I. Sederer MD Preface xxvii Acknowledgments xxxi A Guide for Using the Text xxxiii List of Tables xxxvii List of Figures xxxix Section I Family Therapy in Context 1 The Field of Couples and Family Therapy: Development and Definition 5 2 Family Life in Historical and Sociological Perspective 23 Section II Functional and Dysfunctional Families 3 Understanding the Functional Family 41 4 Understanding the Functional Family in a Variety of Family Forms 59 5 Problems and Dysfunction from an Integrated Family Systems Perspective 75 Section III Family Evaluation 6 The Process of Evaluation 95 7 The Content of Evaluation 107 8 Formulating an Understanding of the Family Problem Areas 117 Section IV Family Treatment 9 Major Family Therapy Schools and Their Treatment Strategies 137 10 Goals 147 11 Family Treatment: Integrated Strategies and Techniques 157 12 The Course of Family Treatment 175 13 Promoting Change in Family Treatment: Issues of Alliance and Resistance 189 14 Family Therapy: General Considerations203 Section V Couples Therapy 15 Dysfunctional Couples and Couples Therapy 221 16 Sex Couples and Sex Therapy 235 17 Couples and Families Breaking Apart: Separation and Divorce 249 Section VI Family Treatment When One Member Has a Psychiatric Disorder or Other Special Problem 18 Family Treatment in the Context of Individual Psychiatric Disorders 267 19 Family Treatment in the Context of Other Special Problems—Violence to Self and Others 301 20 The Family and Treatment of Acute and Chronic Psychiatric Illness 321 21 Working with Families in the Section VII Results of and Guidelines for Recommending Family Therapy 23 Controversies Relative Contraindications and the Use and Misuse of Couples and Family Therapy 371 24 Results: The Outcomes of Couples and Family Therapy 381 Section VIII Ethical Professional and Training Issues 25 Ethical and Professional Issues in Couples and Family Therapy 405 Suggested Reading 419 References 419 Index 421

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Book SynopsisFollowing the undergraduate curriculum set by the British Association of Urological Surgeons, Urology at a Glance offers practical advice on diagnosis and management of one of the most rapidly developing medical specialties.Table of ContentsContributors vii Preface ix About the companion website x Part 1 Urological history, examination and investigations 1 1 Taking a urological history 2 2 Male genital examination 4 3 Female genital examination 6 4 Urological investigations 8 5 Abdominal pain 11 Part 2 Kidney and ureter 15 6 Urolithiasis 16 7 Renal failure 21 Part 3 Bladder 25 8 Lower urinary tract symptoms 26 9 Urinary tract infections 34 10 Urinary incontinence 40 11 Neuropathic bladder 44 Part 4 Andrology 47 12 Scrotal swelling and pain 48 13 Male infertility 52 14 Erectile dysfunction 54 Part 5 Urological cancers 57 15 Urological malignancies 58 16 Haematuria 68 Part 6 Paediatric urology 71 17 Common urological conditions in childhood 72 Part 7 Urological trauma 75 18 Urinary tract trauma including spinal cord injury 76 Part 8 Urological procedures and equipment 81 19 Urological procedures and equipment 82 Index 90

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Book SynopsisTable of Contents1. Introduction - banner colour: white 2. Melanocytic lesions – banner colour: brown 3. Melanoma chapter – banner colour: black 4. Non-melanocytic lesions – banner colour: purple 5. Basal cell carcinoma chapter - banner colour: dark blue 6. Keratinocyte dysplasia chapter - banner colour: light blue 7. Special sites: Acral lesions chapter - banner colour: dark green Special sites: Nail lesions chapter – banner colour: mid green Special sites: Facial lesions chapter - banner colour: pale green Special sites: Scalp lesions chapter - banner colour: bright green Special sites: Trichoscopy – banner colour: light bright green 8. Vascular lesions - banner colour: blood red 9. Inflammoscopy (general dermatology) – banner colour: pink 11. Entodermoscopy chapter - banner colour: orange 10. Genetic lesions – banner colour: yellow 12. Iatrogenic lesions (miscellaneous) - banner colour: grey

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Book SynopsisThe third edition Counselling Skills for Dieticians has been fully revised and updated to reflect the recent developments, research and interests in the field.Table of ContentsForeword xiv About the authors xvi Preface to the third edition xvii Acknowledgements xx Introduction xxi About the companion website xxv Part 1: Using a counselling approach in patient‐centred practice 1 1 The dietitian 3 The role of the dietitian 3 Using a prescriptive approach 4 Control, compliance and responsibility 5 Changing approaches to providing health care 5 Developing a patient‐centred approach 7 Introducing counselling skills 8 Developing a counselling approach 10 Portrait of a dietitian using a counselling approach 10 Qualities for a dietitian to develop 11 Providing care 12 Personal and professional development 12 Self‐awareness 13 Frame of reference 13 Self‐worth 13 Reflective practice 14 Benefits of reflective practice 14 Use of the word ‘reflection’ 15 Different approaches to counselling and psychotherapy 15 Psychoanalytic approach 15 Behavioural and cognitive approaches 16 Humanistic approach 16 Transactional Analysis 17 Systemic therapy 17 Neuro‐linguistic programming 17 Mindfulness 18 Overview of the evidence concerning the use of communication skills in dietetic practice 18 References 19 2 The patient 22 Using a patient‐centred approach 22 The concerns of the patient 23 The feelings of the patient 24 The expectations of the patient 25 The nature of change 26 Change has a ripple effect 26 Change occurs in a number of ways 26 People react and adapt to change in various ways 27 Change is paradoxical, in that we both want it and do not want it 27 Change can have implications of which we are not aware 27 Reactions to change 27 Shock 28 Release of emotion 28 Talking about it 28 Ambivalence 29 Bargaining 29 Doubt about being able to cope 29 Blame 30 Distancing 30 Adapting to change 30 Patient satisfaction 31 References 32 3 The relationship between dietitian and patient 33 Circumstances surrounding the dietitian’s relationship with the patient 33 Core conditions for a helping relationship 34 Empathy 34 Acceptance 37 Genuineness 39 Issues arising between patient and dietitian: power, dependency, transference and counter‐transference 40 Power 40 Dependency 41 Transference and counter‐transference 41 The working alliance 42 A therapeutic bond 42 Goals 43 Tasks 43 Further points to consider 44 References 44 4 Aspects of the helping process 45 The dietitian’s concerns 46 Keeping boundaries: how the dietitian can manage time, confidentiality and referral 46 Establishing a time boundary 47 Maintaining confidentiality 47 Recognising professional and personal limitations: when, how and where to make a referral 50 Recognising the different developmental stages of the helping process 51 Stage 1: Listening to the patient’s story 51 Stage 2: Clarifying what the patient wants 52 Stage 3: Planning ways to achieve goals 54 Looking at the psychological process of change 55 Putting it into practice 55 Coping with ambivalence 57 Incorporating systemic awareness 58 Examples of questions to ask about diet and the home situation 59 How to end 59 Support for the dietitian 61 References 61 5 Conducting a structured interview 62 A framework for the interview 62 Beginnings 63 The interview setting 63 Preparing to provide a helping relationship 64 Opening the interview 65 Forming first impressions 65 Making introductions 68 Finding a starting point 68 Middles 69 Setting the agenda 69 Assessing motivation 71 Making a contract 72 Taking a diet history 73 Giving dietary advice 75 Monitoring the relationship 79 Endings 81 Acknowledging the ending 81 Summarising what has taken place 81 What next? 82 Saying goodbye 82 After the interview 83 References 84 Part 2: The skills 85 6 Active listening 87 The process of listening 87 Attending: a way of demonstrating acceptance 88 Attending is giving someone our attention as fully as we can 88 A listener who conveys acceptance is someone who is safe to talk to 89 Barriers to attending 90 Eye contact 90 Environment 90 Events and emotions 90 Echoes within 91 Attending to non‐verbal communication 91 Voice 91 Eye contact 92 Facial expression 92 Appearance 93 Posture 93 Gesture 93 Discrepancies and incongruities 93 Developing powers of observation 94 Distinguishing between observation and interpretation 94 Managing silences 95 Mirroring 96 Touching 97 References 98 7 Ways of responding 99 The effects of responding 99 Types of response 100 Low‐risk responses 101 Moderate‐risk responses 101 High‐risk responses 101 Very high‐risk responses 103 Self‐disclosure 103 The purpose behind a response 104 The power of language 105 Use of ‘we’, ‘you’ and ‘I’ 105 Language of success or failure 106 Language of doubt 106 Language of negativity 106 Reflective responding 107 The technique of reflecting 108 The skill of reflecting 109 Focusing on feelings 111 Mirroring language 112 When to use reflective responding 113 When reflective responding is not helpful 113 References 114 8 Making helpful interventions 115 Moving towards a helping conversation 115 Helpful interventions 116 Examining attitudes 117 Providing the core conditions when making a helpful intervention 118 Timing and level of intervention 119 Ways to intervene 121 Asking questions 121 Open questions 122 Closed questions 123 Highlighting paradoxes, discrepancies and inconsistencies 123 Confronting absolutes 123 Choosing a focus 124 Addressing sensitive issues 125 When the dietitian does not believe the patient 125 Helping someone towards clearer thinking using CBT 126 Recognising thoughts and distinguishing them from feelings 126 ‘What’s going through your mind when you think that?’ 126 References 130 9 Conveying a clear message: assertiveness in action 131 Counselling skills and assertiveness 131 What is assertive communication? 132 Developing assertiveness 132 Self‐awareness and assertiveness 132 Self‐esteem and assertiveness 133 Communicating feelings 133 Aggression 133 Passivity 134 Manipulation 134 Advantages and disadvantages of assertiveness 134 Advantages 134 Disadvantages 135 Delivering a clear message 135 Preparation and reflection 135 Rehearsal 135 Delivery 135 Examples of assertiveness skills in practice 136 With a patient 136 With a GP practice manager 137 Confronting difficult situations 138 Confrontation from a colleague 139 Confrontation from a patient 139 Confronting a patient 140 Confronting a colleague 141 Handling criticism and praise 142 Criticism 142 Praise 144 Support with handling criticism and praise 145 Dealing with aggressive behaviour 145 Assessing risks 146 Taking care of yourself 146 Defusing the situation 147 Be A DEFUSER 147 Coping with the after‐effects 148 An ABC for conveying a clear message 148 References 150 Part 3: Putting skills into practice: further considerations 151 10 Working with more than one person 153 When others are in the room 153 Reasons for others to be present 153 Context of the interview 154 Risks and benefits of involving another person 154 Issues to consider when others are present 155 Dynamics between those present 155 Agendas of those present 156 Relationships between those present 156 Language and culture of those present 157 Maintaining equity and creating structure and boundaries 158 Maintaining equity 158 Creating structure and boundaries 159 Family meetings 159 Example 160 Who is responsible for finding a solution? 161 Who is leading the consultation? 161 Group work 162 Group size 162 Group demographics 162 Group dynamics 162 Group process 163 Using counselling skills with a group 164 References 165 11 Coping with loss and bereavement 166 How loss concerns dietitians 166 The need to grieve 168 Our reactions to grief 168 The process of grieving 168 How the dietitian can help 169 Loss of weight: a loss or a gain? 171 Loss of self‐esteem 171 Loss of health: living under threat of death 172 Loss of appetite 173 Support for the patient and the dietitian 174 References 175 12 Developing cultural awareness 176 What is culture? 176 Cultural changes within dietetics and the NHS 177 Move away from tradition and hierarchy 177 Prevention of disease and the rise of nutrition 178 Growth of the profession and an increase in diversity 178 Introducing a patient‐centred approach 179 Evidence‐based practice and CPD 179 Stress from change and limited resources 180 Developing cultural awareness 180 Prejudice and its development 181 Attitudes and expectations 182 Effect of prejudice on the helping relationship 182 Towards more effective communication 183 Example 183 Making introductions and establishing credentials 183 Language 184 Boundaries and goal setting 185 Social rituals and customs 186 Making effective use of an interpreter 186 Who is the interpreter? 186 Preparing for the interview 187 Working with an asylum seeker 188 Coping with difficulties 188 Ways of building bridges 188 References 189 13 Working with parents and children 190 Challenges for the dietitian 190 The needs of the child 191 Meeting the family 192 Background 192 Interview 192 Reflections 193 Considerations 193 Making a plan 194 Next meeting 194 Summary of how Sue worked with Peter 195 When a child withdraws 195 Guidelines for handling this situation 196 The angry child 196 Guidelines for handling this situation 196 The well‐behaved child 197 Guidelines for handling this situation 197 Overprotective parents 197 Guidelines for handling this situation 198 Aggressive parents 198 Guidelines for handling this situation 198 The absent parent 198 Guidelines for handling this situation 199 The dying child 199 Guidelines for handling this situation 199 Reference 200 14 Working with difficulties in physical and mental health 201 Minority needs as part of society 201 Effect on patient and dietitian 202 The patient 202 The dietitian 203 Resources for the dietitian to develop 203 Internal resources 203 External resources 204 Physical difficulties 204 Hearing 205 Sight 205 Speech 206 Mobility and movement 207 Appearance 207 Invisible disabilities 208 Mental health 208 Recognising anxiety and depression 208 How the dietitian can help 209 Helping those with eating distress: disordered eating and eating disorders 211 Hearing suicidal thoughts: how can I bear it? 217 Maintaining confidentiality when making a referral 218 References 219 Part 4: Areas for personal and professional development 221 15 Developing self‐awareness 223 Why self‐awareness is important 223 Ways to develop self‐awareness 224 Time for ourselves 224 Becoming more mindful 224 Self‐esteem 225 Ways to build self‐esteem 226 Acknowledgement 226 Tips for building self‐esteem 227 Coping with stress 227 Ways to unwind 229 Keeping a reflective diary 231 References 231 16 Giving and receiving support 233 When support is needed 233 Knowing your limits 234 Supporting yourself 235 Reflecting on practice 235 Creating a dialogue 235 Building a support network 236 Asking for support 237 Tips for asking for support 237 Giving support 238 Tips for giving support 239 Giving constructive support 239 Support from training, assessment and monitoring 240 Training in communication skills 241 Training in counselling skills 242 Supportive peer discussion 243 Making arrangements 243 Managing the session 243 Supervision 244 Personal counselling 244 What does counselling involve? 245 Who seeks counselling? 246 References 247 Index 248

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Book SynopsisAn emerging field at the interface of biology and engineering, mechanobiology explores the mechanisms by which cells sense and respond to mechanical signalsand holds great promise in one day unravelling the mysteries of cellular and extracellular matrix mechanics to cure a broad range of diseases. Mechanobiology: Exploitation for Medical Benefit presents a comprehensive overview of principles of mechanobiology, highlighting the extent to which biological tissues are exposed to the mechanical environment, demonstrating the importance of the mechanical environment in living systems, and critically reviewing the latest experimental procedures in this emerging field. Featuring contributions from several top experts in the field, chapters begin with an introduction to fundamental mechanobiological principles; and then proceed to explore the relationship of this extensive force in nature to tissues of musculoskeletal systems, heart and lung vasculature, the kidney glomerulusTable of Contents List of Contributors xiii Preface xvii 1 Extracellular Matrix Structure and Stem Cell Mechanosensing 1Nicholas D. Evans and Camelia G. Tusan 1.1 Mechanobiology 1 1.2 Stem Cells 3 1.3 Substrate Stiffness in Cell Behavior 5 1.3.1 A Historical Perspective on Stiffness Sensing 5 1.4 Stem Cells and Substrate Stiffness 7 1.4.1 ESCs and Substrate Stiffness 8 1.4.2 Collective Cell Behavior in Substrate Stiffness Sensing 11 1.5 Material Structure and Future Perspectives in Stem Cell Mechanobiology 14 1.6 Conclusion 15 References 16 2 Molecular Pathways of Mechanotransduction: From Extracellular Matrix to Nucleus 23Hamish T. J. Gilbert and Joe Swift 2.1 Introduction: Mechanically Influenced Cellular Behavior 23 2.2 Mechanosensitive Molecular Mechanisms 24 2.3 Methods Enabling the Study of Mechanobiology 29 2.4 Conclusion 34 Acknowledgements 34 References 34 3 Sugar-Coating the Cell: The Role of the Glycocalyx in Mechanobiology 43Stefania Marcotti and Gwendolen C. Reilly 3.1 What is the Glycocalyx? 43 3.2 Composition of the Glycocalyx 44 3.3 Morphology of the Glycocalyx 45 3.4 Mechanical Properties of the Glycocalyx 46 3.5 Mechanobiology of the Endothelial Glycocalyx 49 3.6 Does the Glycocalyx Play a Mechanobiological Role in Bone? 50 3.7 Glycocalyx in Muscle 52 3.8 How Can the Glycocalyx be Exploited for Medical Benefit? 53 3.9 Conclusion 53 References 54 4 The Role of the Primary Cilium in Cellular Mechanotransduction: An Emerging Therapeutic Target 61Kian F. Eichholz and David A. Hoey 4.1 Introduction 61 4.2 The Primary Cilium 63 4.3 Cilia-Targeted Therapeutic Strategies 68 4.4 Conclusion 70 Acknowledgements 70 References 70 5 Mechanosensory and Chemosensory Primary Cilia in Ciliopathy and Ciliotherapy 75Surya M. Nauli, Rinzhin T. Sherpa, Caretta J. Reese, and Andromeda M. Nauli 5.1 Introduction 75 5.2 Mechanobiology and Diseases 76 5.3 Primary Cilia as Biomechanics 78 5.4 Modulating Mechanobiology Pathways 83 5.5 Conclusion 85 References 86 6 Mechanobiology of Embryonic Skeletal Development: Lessons for Osteoarthritis 101Andrea S. Pollard and Andrew A. Pitsillides 6.1 Introduction 101 6.2 An Overview of Embryonic Skeletal Development 102 6.3 Regulation of Joint Formation 103 6.4 Regulation of Endochondral Ossification 105 6.5 An Overview of Relevant Osteoarthritic Joint Changes 106 6.6 Lessons for Osteoarthritis from Joint Formation 108 6.7 Lessons for Osteoarthritis from Endochondral Ossification 109 6.8 Conclusion 110 Acknowledgements 111 References 111 7 Modulating Skeletal Responses to Mechanical Loading by Targeting Estrogen Receptor Signaling 115Gabriel L. Galea and Lee B. Meakin 7.1 Introduction 115 7.2 Biomechanical Activation of Estrogen Receptor Signaling: In Vitro Studies 116 7.3 Skeletal Consequences of Altered Estrogen Receptor Signaling: In Vivo Mouse Studies 120 7.4 Skeletal Consequences of Human Estrogen Receptor Polymorphisms: Human Genetic and Exercise-Intervention Studies 125 7.5 Conclusion 126 References 126 8 Mechanical Responsiveness of Distinct Skeletal Elements: Possible Exploitation of Low Weight-Bearing Bone 131Simon C. F. Rawlinson 8.1 Introduction 131 8.2 Anatomy and Loading-Related Stimuli 132 8.3 Preosteogenic Responses In Vitro 135 8.4 Site-Specific, Animal-Strain Differences 136 8.5 Exploitation of Regional Information 137 8.6 Conclusion 138 References 138 9 Pulmonary Vascular Mechanics in Pulmonary Hypertension 143Zhijie Wang, Lian Tian, and Naomi C. Chesler 9.1 Introduction 143 9.2 Pulmonary Vascular Mechanics 143 9.3 Measurements of Pulmonary Arterial Mechanics 147 9.4 Mechanobiology in Pulmonary Hypertension 150 9.5 Computational Modeling in Pulmonary Circulation 151 9.6 Impact of Pulmonary Arterial Biomechanics on the Right Heart 152 9.7 Conclusion 153 References 153 10 Mechanobiology and the Kidney Glomerulus 161Franziska Lausecker, Christoph Ballestrem, and Rachel Lennon 10.1 Introduction 161 10.2 Glomerular Filtration Barrier 161 10.3 Podocyte Adhesion 163 10.4 Glomerular Disease 165 10.5 Forces in the Glomerulus 166 10.6 Mechanosensitive Components and Prospects for Therapy 167 10.7 Conclusion 169 References 169 11 Dynamic Remodeling of the Heart and Blood Vessels: Implications of Health and Disease 175Ken Takahashi, Hulin Piao, and Keiji Naruse 11.1 Introduction 175 11.2 Causes of Remodeling 176 11.3 Mechanical Transduction in Cardiac Remodeling 177 11.4 The Remodeling Process 178 11.5 Conclusion 183 References 183 12 Aortic Valve Mechanobiology: From Organ to Cells 191K. Jane Grande-Allen, Daniel Puperi, Prashanth Ravishankar, and Kartik Balachandran 12.1 Introduction 191 12.2 Mechanobiology at the Organ Level 192 12.3 Mechanobiology at the Cellular Level 197 12.4 Conclusion 201 Acknowledgments 201 References 201 13 Testing the Perimenopause Ageprint using Skin Visoelasticity under Progressive Suction 207Gérald E. Piérard, Claudine Piérard-Franchimont, Ulysse Gaspard, Philippe Humbert, and Sébastien L. Piérard 13.1 Introduction 207 13.2 Gender-Linked Skin Aging 208 13.3 Dermal Aging, Thinning, and Wrinkling 209 13.4 Skin Viscoelasticity under Progressive Suction 209 13.5 Skin Tensile Strength during the Perimenopause 211 13.6 Conclusion 214 Acknowledgements 215 References 216 14 Mechanobiology and Mechanotherapy for Skin Disorders 221Chao-Kai Hsu and Rei Ogawa 14.1 Introduction 221 14.2 Skin Disorders Associated with Mechanobiological Dysfunction 223 14.3 Mechanotherapy 231 14.4 Conclusion 232 Acknowledgement 232 References 233 15 Mechanobiology and Mechanotherapy for Cutaneous Wound-Healing 239Chenyu Huang, Yanan Du, and Rei Ogawa 15.1 Introduction 239 15.2 The Mechanobiology of Cutaneous Wound-Healing 240 15.3 Mechanotherapy to Improve Cutaneous Wound-Healing 242 15.4 Future Considerations 246 References 246 16 Mechanobiology and Mechanotherapy for Cutaneous Scarring 255Rei Ogawa and Chenyu Huang 16.1 Introduction 255 16.2 Cutaneous Wound-Healing and Mechanobiology 255 16.3 Cutaneous Scarring and Mechanobiology 256 16.4 Cellular and Tissue Responses to Mechanical Forces 257 16.5 Keloids and Hypertrophic Scars and Mechanobiology 258 16.6 Relationship Between Scar Growth and Tension 260 16.7 A Hypertrophic Scar Animal Model Based on Mechanotransduction 261 16.8 Mechanotherapy for Scar Prevention and Treatment 262 16.9 Conclusion 263 References 264 17 Mechanobiology and Mechanotherapy for the Nail 267Hitomi Sano and Rei Ogawa 17.1 Introduction 267 17.2 Nail Anatomy 267 17.3 Role of Mechanobiology in Nail Morphology 268 17.4 Nail Diseases and Mechanical Forces 269 17.5 Current Nail Treatment Strategies 270 17.6 Mechanotherapy for Nail Deformities 270 17.7 Conclusion 271 References 271 18 Bioreactors: Recreating the Biomechanical Environment In Vitro 275James R. Henstock and Alicia J. El Haj 18.1 The Mechanical Environment: Forces in the Body 275 18.2 Bioreactors: A Short History 276 18.3 Bioreactor Types 278 18.4 Commercial versus Homemade Bioreactors 288 18.5 Automated Cell-Culture Systems 289 18.6 The Future of Bioreactors in Research and Translational Medicine 290 References 291 19 Cell Sensing of the Physical Properties of the Microenvironment at Multiple Scales 297Julien E. Gautrot 19.1 Introduction 297 19.2 Cells Sense their Mechanical Microenvironment at the Nanoscale Level 298 19.3 Cell Sensing of the Nanoscale Physicochemical Landscape of the Environment 306 19.4 Cell Sensing of the Microscale Geometry and Topography of the Environment 312 19.5 Conclusion 319 References 319 20 Predictive Modeling in Musculoskeletal Mechanobiology 331Hanifeh Khayyeri, Hanna Isaksson, and Patrick J. Prendergast 20.1 What is Mechanobiology? Background and Concepts 331 20.2 Examples of Mechanobiological Experiments 333 20.3 Modeling Mechanobiological Tissue Regeneration 337 20.4 Mechanoregulation Theories for Bone Regeneration 338 20.5 Use of Computational Modeling Techniques to Corroborate Theories and Predict Experimental Outcomes 340 20.6 Horizons of Computational Mechanobiology 341 References 343 21 Porous Bone Graft Substitutes: When Less is More 347Charlie Campion and Karin A. Hing 21.1 Introduction 347 21.2 Bone: The Ultimate Smart Material 350 21.3 Bone-Grafting Classifications 353 21.4 Synthetic Bone Graft Structures 356 21.5 Conclusion 361 References 362 22 Exploitation of Mechanobiology for Cardiovascular Therapy 373Winston Elliott, Amir Keshmiri, and Wei Tan 22.1 Introduction 373 22.2 Arterial Wall Mechanics and Mechanobiology 374 22.3 Mechanical Signal and Mechanotransduction on the Arterial Wall 375 22.4 Physiological and Pathological Responses to Mechanical Signals 377 22.5 The Role of Vascular Mechanics in Modulating Mechanical Signals 378 22.6 Therapeutic Strategies Exploiting Mechanobiology 380 22.7 The Role of Hemodynamics in Mechanobiology 381 22.8 Conclusion 390 References 391 Index 401

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Book SynopsisDental Benefits and Practice Management: A Guide for Successful Practices is a practical tool that helps you manage your office in tune with the realities of modern dental practice. Written by both dentists and insurance industry professionals Practical explanations to effectively and legally process claims Describes the changes in dental practice management to make your practice patient centered Competitive strategies for dentists and organizations Table of ContentsList of contributors, ix Preface, xi Acknowledgments, xv Part I: History of Dental Insurance, 1 1 Why dental benefits?, 3Michael M. Okuji 2 Dental benefits: Get it done, 21Michael M. Okuji 3 Dental benefits: Get it right, 47Michael M. Okuji Part II: Dental Claim System, 69 4 Patient]centered practice, 71David Okuji 5 Streamlined dental practice, 93Michael M. Okuji & Dennis Lewis 6 Patient Protection and Affordable Care Act, 109Michael M. Okuji & David Okuji Part III: Competitive Strategies, 127 7 Ethics and ethical behavior, 129Gary Herman 8 Stay out of trouble, 147Matthew Cassady 9 Analysis to action, 169Michael M. Okuji Index, 195

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Book SynopsisReflects on developments in noninvasive electromyography, and includes advances and applications in signal detection, processing and interpretation Addresses EMG imaging technology together with the issue of decomposition of surface EMG Includes advanced single and multi-channel techniques for information extraction from surface EMG signals Presents the analysis and information extraction of surface EMG at various scales, from motor units to the concept of muscle synergies. Table of Contents1 Physiology of Muscle Activation and Force Generation 1R. M. Enoka and J. Duchateau 2 Biophysics of the Generation of EMG Signals 30D. Farina, D. F. Stegeman, and R. Merletti 3 Detection and Conditioning of Surface EMG Signals 54R. Merletti, A. Botter, and U. Barone 4 Single-Channel Techniques for Information Extraction from the Surface EMG Signal 91E. A. Clancy, F. Negro, and D. Farina 5 Techniques for Information Extraction from the Surface EMG Signal: High-Density Surface EMG 126R. Merletti, T. M. Vieira, and D. Farina 6 Muscle Coordination, Motor Synergies, and Primitives from Surface EMG 158Y. P. Ivanenko, A. D'avella, and F. Lacquaniti 7 Surface EMG Decomposition 180A. Holobar, D. Farina, and D. Zazula 8 EMG Modeling and Simulation 210M. M. Lowery 9 Electromyography-Driven Modeling for Simulating Subject-Specific Movement at the Neuromusculoskeletal Level 247M. Sartori, D. G. Lloyd, T. F. Besier, J. W. Fernandez, and D. Farina 10 Muscle Force and Myoelectric Manifestations of Muscle Fatigue in Voluntary and Electrically Elicited Contractions 273R. Merletti, B. Afsharipour, J. Dideriksen, and D. Farina 11 EMG of Electrically Stimulated Muscles 311A. Botter and R. Merletti 12 Surface EMG Applications in Neurophysiology 333S. Baudry, M. A. Minetto, and J. Duchateau 13 Surface EMG in Ergonomics and Occupational Medicine 361M. Gazzoni, B. Afsharipour, and R.Merletti 14 Applications in Proctology and Obstetrics 392R. Merletti 15 EMG and Posture in Its Narrowest Sense 408T. M. Vieira, D. Farina, and I. D. Loram 16 Applications in Movement and Gait Analysis 440A. Merlo and I. Campanini 17 Applications in Musculoskeletal Physical Therapy 460D. Falla 18 Surface EMG Biofeedback 485A. Gallina, M. Gazzoni, D. Falla, and R. Merletti 19 EMG in Exercise Physiology and Sports 501A. Rainoldi, T. Moritani, and G. Boccia 20 Surface Electromyography for Man–Machine Interfacing in Rehabilitation Technologies 540D. Farina and M. Sartori Index 561

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Book SynopsisComplications from dental procedures are inevitable and encountered by all dental professionals. Avoiding and Treating Dental Complications: Best Practices in Dentistry is designed to address proper management of these situations in everyday practice. Covers a range of dental issues and complications found in daily practice Written by experts in each specialty Features tables and charts for quick information Includes clinical photographs and radiographs Table of ContentsList of contributors, vi Acknowledgments, viii 1 Best practices: Restorative complications, 1 2 Periodontal complications, 29 3 Endodontic complications, 50 4 Prosthodontics complications, 73 5 Oral surgery complications, 103 6 Complications of local anesthesia, sedation, and general anesthesia, 120 7 Implant complications, 144 8 Pediatric dentistry complications and challenges, 176 9 Orthodontic complications and the periodontal aspects related to clinical orthodontics, 202 Index, 237

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Book SynopsisProvides a comprehensive overview of wireless computing in medicine, with technological, medical, and legal advances This book brings together the latest work of leading scientists in the disciplines of Computing, Medicine, and Law, in the field of Wireless Health. The book is organized into three main sections. The first section discusses the use of distributed computing in medicine. It concentrates on methods for treating chronic diseases and cognitive disabilities like Alzheimer's, Autism, etc. It also discusses how to improve portability and accuracy of monitoring instruments and reduce the redundancy of data. It emphasizes the privacy and security of using such devices. The role of mobile sensing, wireless power and Markov decision process in distributed computing is also examined. The second section covers nanomedicine and discusses how the drug delivery strategies for chronic diseases can be efficiently improved by Nanotechnology enabled materials and devices suTable of ContentsContributors xiii Foreword xvii Preface xix PART I INTRODUCTION 1 1 Introduction to Wireless Computing in Medicine 3Amber Bhargava, Mary Mehrnoosh Eshaghian-Wilner, Arushi Gupta, Alekhya Sai Nuduru Pati, Kodiak Ravicz, and Pujal Trivedi 1.1 Introduction, 3 1.2 Definition of Terms, 5 1.3 Brief History of Wireless Healthcare, 5 1.4 What is Wireless Computing? 6 1.5 Distributed Computing, 7 1.6 Nanotechnology in Medicine, 10 1.7 Ethics of Medical Wireless Computing, 12 1.8 Privacy in Wireless Computing, 13 1.9 Conclusion, 14 References, 14 2 Nanocomputing and Cloud Computing 17T. Soren Craig, Mary Mehrnoosh Eshaghian-Wilner, Nikila Goli, Arushi Gupta, Shiva Navab, Alekhya Sai Nuduru Pati, Kodiak Ravicz, Gaurav Sarkar, and Ben Shiroma 2.1 Introduction, 17 2.2 Nanocomputing, 18 2.3 Cloud Computing, 30 2.4 Conclusion, 37 Acknowledgment, 37 References, 37 PART II PERVASIVE WIRELESS COMPUTING IN MEDICINE 41 3 Pervasive Computing in Hospitals 43Janet Meiling Wang-Roveda, Linda Powers, and Kui Ren 3.1 Introduction, 43 3.2 Architecture of Pervasive Computing in Hospitals, 45 3.3 Sensors, Devices, Instruments, and Embedded Systems, 49 3.4 Data Acquisition in Pervasive Computing, 59 3.5 Software Support for Context-Aware and Activity Sharing Services, 63 3.6 Data and Information Security, 66 3.7 Conclusion, 71 Acknowledgment, 71 References, 72 4 Diagnostic Improvements: Treatment and Care 79Xiaojun Xian 4.1 Introduction, 79 4.2 System Design, 81 4.3 Body Sensor Network, 82 4.4 Portable Sensors, 84 4.5 Wearable Sensors, 88 4.6 Implantable Sensors, 94 4.7 Wireless Communication, 95 4.8 Mobile Base Unit, 97 4.9 Conclusion and Challenges, 98 Acknowledgment, 99 References, 99 5 Collaborative Opportunistic Sensing of Human Behavior with Mobile Phones 107Luis A. Castro, Jessica Beltran-Marquez, Jesus Favela, Edgar Chavez, Moises Perez, Marcela Rodriguez, Rene Navarro, and Eduardo Quintana 5.1 Health and Mobile Sensing, 107 5.2 The InCense Sensing Toolkit, 110 5.3 Sensing Campaign 1: Detecting Behaviors Associated with the Frailty Syndrome Among Older Adults, 119 5.4 Sensing Campaign 2: Detecting Problematic Behaviors among Elders with Dementia, 123 5.5 Discussion, 131 5.6 Conclusions and Future Work, 132 References, 133 6 Pervasive Computing to Support Individuals with Cognitive Disabilities 137Monica Tentori, José Mercado, Franceli L. Cibrian, and Lizbeth Escobedo 6.1 Introduction, 137 6.2 Wearable and Mobile Sensing Platforms to Ease the Recording of Data Relevant to Clinical Case Assessment, 144 6.3 Augmented Reality and Mobile and Tangible Computing to Support Cognition, 151 6.4 Serious Games and Exergames to Support Motor Impairments, 158 6.5 Conclusions, 168 Acknowledgments, 172 References, 172 7 Wireless Power for Implantable Devices: A Technical Review 187Nikita Ahuja, Mary Mehrnoosh Eshaghian-Wilner, Zhuochen Ge, Renjun Liu, Alekhya Sai Nuduru Pati, Kodiak Ravicz, Mike Schlesinger, Shu Han Wu, and Kai Xie 7.1 Introduction, 187 7.2 History of Wireless Power, 189 7.3 Approach of Wireless Power Transmission, 191 7.4 A Detailed Example of Magnetic Coupling Resonance, 194 7.5 Popular Standards, 199 7.6 Wireless Power Transmission in Medical use, 201 7.7 Conclusion, 204 Acknowledgments, 205 References, 205 8 Energy-Efficient Physical Activity Detection in Wireless Body Area Networks 211Daphney-Stavroula Zois, Sangwon Lee, Murali Annavaram, and Urbashi Mitra 8.1 Introduction, 211 8.2 Knowme Platform, 215 8.3 Energy Impact of Design Choices, 217 8.4 Problem Formulation, 228 8.5 Sensor Selection Strategies, 232 8.6 Alternative Problem Formulation, 237 8.7 Sensor Selection Strategies for the Alternative Formulation, 241 8.8 Experiments, 244 8.9 Related Work, 254 8.10 Conclusion, 256 Acknowledgments, 257 References, 257 9 Markov Decision Process for Adaptive Control of Distributed Body Sensor Networks 263Shuping Liu, Anand Panangadan, Ashit Talukder, and Cauligi S. Raghavendra 9.1 Introduction, 263 9.2 Rationale for MDP Formulation, 265 9.3 Related Work, 268 9.4 Problem Statement, Assumptions, and Approach, 269 9.5 MDP Model for Multiple Sensor Nodes, 272 9.6 Communication, 274 9.7 Simulation Results, 276 9.8 Conclusions, 292 Acknowledgment, 294 References, 294 PART III NANOSCALE WIRELESS COMPUTING IN MEDICINE 297 10 An Introduction to Nanomedicine 299Amber Bhargava, Janet Cheung, Mary Mehrnoosh Eshaghian-Wilner, Wan Lee, Kodiak Ravicz, Mike Schlesinger, Yesha Shah, and Abhishek Uppal 10.1 Introduction, 299 10.2 Nanomedical Technology, 301 10.3 Detection, 303 10.4 Treatment, 305 10.5 Biocompatibility, 309 10.6 Power, 311 10.7 Computer Modeling, 313 10.8 Research Institutions, 315 10.9 Conclusion, 317 Acknowledgments, 317 References, 317 11 Nanomedicine Using Magneto-Electric Nanoparticles 323Mary Mehrnoosh Eshaghian-Wilner, Andrew Prajogi, Kodiak Ravicz, Gaurav Sarkar, Umang Sharma, Rakesh Guduru, and Sakhrat Khizroev 11.1 Introduction, 323 11.2 Overview of MENs, 324 11.3 Experiment 1: Externally Controlled On-Demand Release of Anti-HIV Drug Azttp Using Mens as Carriers, 325 11.4 Experiment 2: Mens to Enable Field-Controlled High-Specificity Drug Delivery to Eradicate Ovarian Cancer Cells, 331 11.5 Experiment 3: Magnetoelectric “Spin” on Stimulating the Brain, 339 11.6 Bioceramics: Bone Regeneration and MNS, 348 11.7 Conclusion, 351 References, 353 12 DNA Computation in Medicine 359Noam Mamet and Ido Bachelet 12.1 Background for the Non-Biologist, 359 12.2 Introduction, 362 12.3 In Vitro Computing, 364 12.4 Computation in Vivo, 370 12.5 Challenges, 373 12.6 Glimpse into the Future, 373 References, 374 13 Graphene-Based Nanosystems for the Detection of Proteinic Biomarkers of Disease: Implication in Translational Medicine 377Farid Menaa, Sandeep Kumar Vashist, Adnane Abdelghani, and Bouzid Menaa 13.1 Introduction, 377 13.2 Structural and Physicochemical Properties of Graphene and Main Derivatives, 379 13.3 Graphene and Derivatives-Based Biosensing Nanosystems and Applications, 382 13.4 Conclusion and Perspectives, 389 Conflict of Interest, 390 Abbreviations, 390 References, 391 14 Modeling Brain Disorders in Silicon Nanotechnologies 401Alice C. Parker, Saeid Barzegarjalali, Kun Yue, Rebecca Lee, and Sukanya Patil 14.1 Introduction, 401 14.2 The BioRC Project, 402 14.3 Background: BioRC Neural Circuits, 404 14.4 Modeling Synapses with CNT Transistors, 408 14.5 Modeling OCD with Hybrid CMOS/Nano Circuits, 410 14.6 The Biological Cortical Neuron and Hybrid Electronic Cortical Neuron, 411 14.7 Biological OCD Circuit and Biomimetic Model, 412 14.8 Indirect Pathway: The Braking Mechanism, 413 14.9 Direct Pathway: The Accelerator, 414 14.10 Typical and Atypical Responses, 415 14.11 Modeling Schizophrenic Hallucinations with Hybrid CMOS/Nano Circuits, 416 14.12 Explanation for Schizophrenia Symptoms, 416 14.13 Disinhibition due to Miswiring, 418 14.14 Our Hybrid Neuromorphic Prediction Network, 418 14.15 Simulation Results, 419 14.16 Numerical Analysis of False Firing, 421 14.17 Modeling PD with CMOS Circuits, 422 14.18 Modeling MS with CMOS Circuits, 424 14.19 Demyelination Circuit, 425 14.20 Conclusions and Future Trends, 426 References, 428 15 Linking Medical Nanorobots to Pervasive Computing 431Sylvain Martel 15.1 Introduction, 431 15.2 Complementary Functionalities, 432 15.3 Main Specifications for such Nanorobotic Agents (Nanorobots), 433 15.4 Medical Nanorobotic Agents—An Example, 436 15.5 Nanorobotic Communication Links Allowing Pervasive Computing, 438 15.6 Types of Information, 439 15.7 Medical Nanorobotic Agents for Monitoring and Early Detection, 440 15.8 Medical Nanorobotics and Pervasive Computing—Main Conditions that must be met for its Feasibility, 442 15.9 Conclusion, 443 References, 444 16 Nanomedicine’s Transversality: Some Implications of the Nanomedical Paradigm 447José J. López and Mathieu Noury 16.1 Introduction, 447 16.2 Nanomedicine’s Promises, 448 16.3 Analysing Implications of the Nanomedicine Paradigm, 451 16.4 The Molecular Underpinnings of Nanomedicine’s Transversality, 456 16.5 Nanomedicine as Predictive Medicine, 457 16.6 Nanomedicine as Personalized Medicine, 460 16.7 Nanomedicine as Regenerative Medicine, 465 16.8 Conclusion, 466 References, 468 PART IV ETHICAL AND LEGAL ASPECTS OF WIRELESS COMPUTING IN MEDICINE 473 17 Ethical Challenges of Ubiquitous Health Care 475William Sims Bainbridge 17.1 Introduction, 475 17.2 A Philosophical Framework, 478 17.3 Information Deviance, 480 17.4 The Current Frenzy, 482 17.5 Genetic Informatics, 485 17.6 Ubiquitous Information Technology, 489 17.7 Stasis versus Progress, 492 17.8 Problematic Ethics, 494 17.9 Leadership in Science and Engineering Ethics, 496 17.10 Conclusion, 498 References, 499 18 The Ethics of Ubiquitous Computing in Health Care 507Clark A. Miller, Heather M. Ross, Gaymon Bennett, and J. Benjamin Hurlbut 18.1 Introduction, 507 18.2 Ubiquitous Computing and the Transformation of Health Care: Three Visions, 511 18.3 Case Study: Cardiac Implanted Electrical Devices, 516 18.4 Ethical Reflections, 521 18.5 Conclusions: The Need for Socio-Technical Design, 534 References, 537 19 Privacy Protection of Electronic Healthcare Records in e-Healthcare Systems 541Fredrick Japhet Mtenzi 19.1 Introduction, 541 19.2 Security and Privacy Concerns of EHR in e-Healthcare Systems, 545 19.3 Privacy Laws and Regulations of EHRs, 547 19.4 Privacy of EHRs in e-Healthcare Systems, 552 19.5 Discussion and Conclusion, 558 19.6 Contributions and Future Research, 559 References, 561 20 Ethical, Privacy, and Intellectual Property Issues in Nanomedicine 567Katie Atalla, Ayush Chaudhary, Mary Mehrnoosh Eshaghian-Wilner, Arushi Gupta, Raj Mehta, Adarsh Nayak, Andrew Prajogi, Kodiak Ravicz, Ben Shiroma, and Pujal Trivedi 20.1 Introduction, 567 20.2 Ethical Issues, 568 20.3 Privacy Issues, 579 20.4 IP Issues, 590 20.5 Conclusion, 596 Acknowledgments, 596 References, 596 PART V CONCLUSION 601 21 Concluding Remarks 603Zhaoqi Chen, Mary Mehrnoosh Eshaghian-Wilner, Kalyani Gonde, Kodiak Ravicz, Rakshith Saligram and Mike Schlesinger 21.1 Wireless Computing in Health Care, 603 21.2 Nanomedicine, 606 21.3 Ethical, Privacy, and Intellectual Property Issues of Nanomedicine and Wireless Computing, 609 21.4 Conclusions, 610 Acknowledgments, 610 References, 610 Index 613

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Book SynopsisThis book covers the recent advances in the development of bioelectronics systems and their potential application in future biomedical applications starting from system design to signal processing for physiological monitoring, to in situ biosensing. Advanced Bioelectronic Materials contributions from distinguished international scholars whose backgrounds mirror the multidisciplinary readership ranging from the biomedical sciences, biosensors and engineering communities with diverse backgrounds, interests and proficiency in academia and industry. The readers will benefit from the widespread coverage of the current literature, state-of-the-art overview of all facets of advanced bioelectronics materials ranging from real time monitoring, in situ diagnostics, in vivo imaging, image-guided therapeutics, biosensors, and translational biomedical devices and personalized monitoring.Table of ContentsPreface xv Part 1: Recent Advances in Bioelectronics 1 1 Micro- and Nanoelectrodes in Protein-Based Electrochemical Biosensors for Nanomedicine and Other Applications 3 Niina J. Ronkainen 1.1 Introduction 4 1.2 Microelectrodes 7 1.2.1 Electrochemistry and Advantages of Microelectrodes 7 1.2.2 Applications, Cleaning, and Performance of Microelectrodes 16 1.3 Nanoelectrodes 18 1.3.1 Electrochemistry and Advantages of Nanoelectrodes 21 1.3.2 Applications and Performance of Nanoelectrodes 23 1.4 Integration of the Electronic Transducer, Electrode, and Biological Recognition Components (such as Enzymes) in Nanoscale-Sized Biosensors and Their Clinical Applications 26 1.5 Conclusion 27 Acknowledgment 28 References 28 2 Radio-Frequency Biosensors for Label-Free Detection of Biomolecular Binding Systems 35 Hee-Jo Lee1, Sang-Gyu Kim, and Jong-Gwan Yook 2.1 Overview 35 2.2 Introduction 36 2.3 Carbon Nanotube-Based RF Biosensor 37 2.3.1 Carbon Nanotube 37 2.3.2 Fabrications of Interdigital Capacitors with Carbon Nanotube 38 2.3.3 Functionalization of Carbon Nanotube 39 2.3.4 Measurement and Results 40 2.4 Resonator-Based RF Biosensor 40 2.4.1 Resonator 40 2.4.2 Sample Preparation and Measurement 42 2.4.3 Functionalization of Resonator 42 2.5 Active System-Based RF Biosensor 45 2.5.1 Principle and Configuration of System 45 2.5.2 Fabrication of RF Active System with Resonator 46 2.5.2.1 Functionalization of Resonator 46 2.5.3 Measurement and Result 47 2.6 Conclusions 49 Abbreviations 51 References 52 3 Affinity Biosensing: Recent Advances in Surface Plasmon Resonance for Molecular Diagnostics 55 S. Scarano, S. Mariani, and M. Minunni 3.1 Introduction 56 3.2 Artists of the Biorecognition: New Natural and Synthetic Receptors as Sensing Elements 58 3.2.1 Antibodies and Their Mimetics 58 3.2.2 Nucleic Acids and Analogues 62 3.2.3 Living Cells 63 3.3 Recent Trends in Bioreceptors Immobilization 65 3.4 Trends for Improvements of Analytical Performances in Molecular Diagnostics 69 3.4.1 Coupling Nanotechnology to Biosensing 70 3.4.2 Microfluidics and Microsystems 76 3.4.3 Hyphenation 78 3.5 Conclusions 78 References 80 4 Electropolymerized Materials for Biosensors 89 Gennady Evtugyn, Anna Porfi reva and Tibor Hianik 4.1 Introduction 89 4.2 Electropolymerized Materials Used in Biosensor Assembly 93 4.2.1 General Characteristic of Electropolymerization Techniques 93 4.2.2 Instrumentation Tools for Monitoring of the Redox-Active Polymers in the Biosensor Assembly 97 4.2.3 Redox-Active Polymers Applied in Biosensor Assembly 99 4.3 Enzyme Sensors 107 4.3.1 PANI-Based Enzyme Sensors 107 4.3.2 PPY and Polythiophene-Based Enzyme Sensors 117 4.3.3 Enzyme Sensors Based on Other Redox-Active Polymers Obtained by Electropolymerization 127 4.3.4 Enzyme Sensors Based on Other Polymers Bearing Redox Groups 135 4.4 Immunosensors Based on Redox-Active Polymers 137 4.5 DNA Sensors Based on Redox-Active Polymers 149 4.5.1 PANI-based DNA Sensors and Aptasensors 149 4.5.2 PPY-Based DNA Sensors 153 4.5.3 Thiophene Derivatives in the DNA Sensors 157 4.5.4 DNA Sensors Based on Polyphenazines and Other Redox-Active Polymers 159 4.6 Conclusion 162 Acknowledgments 163 References 163 Part 2 Advanced Nanostructures in Biosensing 187 5 Graphene-Based Electrochemical Platform for Biosensor Applications 189 Yusoff Norazriena, Alagarsamy Pandikumar, Huang Nay Ming, and Lim Hong Ngee2,3 5.1 Introduction 189 5.2 Graphene 192 5.3 Synthetic Methods for Graphene 195 5.4 Properties of Graphene 197 5.5 Multi-functional Applications of Graphene 199 5.6 Electrochemical Sensor 200 Graphene as Promising Materials for Electrochemical Biosensors 201 5.6.1 Graphene-Based Modified Electrode for Glucose Sensors 201 5.6.2 Graphene-Based Modified Electrode for NADH Sensors 202 5.6.3 Graphene-Based Modified Electrode for NO Sensors 204 5.6.4 Graphene-Based Modified Electrode for H2O 206 5.7 Conclusion and Future Outlooks 207 References 208 6 Fluorescent Carbon Dots for Bioimaging 215 Suresh Kumar Kailasa, Vaibhavkumar N. Mehta1, Nazim Hasan and Hui-Fen Wu 6.1 Introduction 215 6.2 CDs as Fluorescent Probes for Imaging of Biomolecules and Cells 216 6.3 Conclusions and Perspectives 224 References 224 7 Enzyme Sensors Based on Nanostructured Materials 229 Nada F. Atta, Shimaa M. Ali, and Ahmed Galal 7.1 Biosensors and Nanotechnology 229 7.2 Biosensors Based on Carbon Nanotubes (CNTs) 230 7.2.1 Glucose Biosensors 233 7.2.2 Cholesterol Biosensors 237 7.2.3 Tyrosinase Biosensors 240 7.2.4 Urease Biosensors 243 7.2.5 Acetylcholinesterase Biosensors 244 7.2.6 Horseradish Peroxidase Biosensors 246 7.2.7 DNA Biosensors 248 7.3 Biosensors Based on Magnetic Nanoparticles 252 7.4 Biosensors Based on Quantum Dots 260 7.5 Conclusion 267 References 268 8 Biosensor Based on Chitosan Nanocomposite 277 Baoqiang Li, Yinfeng Cheng, Feng Xu, Lei Wang, Daqing Wei, Dechang Jia, Yujie Feng, and Yu Zhou 8.1 Introduction 278 8.2 Chitosan and Chitosan Nanomaterials 278 8.2.1 Physical and Chemical Properties of Chitosan 279 8.2.2 Biocompatibility of Chitosan 280 8.2.3 Chitosan Nanomaterials 281 8.2.3.1 Blending 281 8.2.3.2 In Situ Hybridization 282 8.2.3.3 Chemical Grafting 285 8.3 Application of Chitosan Nanocomposite in Biosensor 285 8.3.1 Biosensor Configurations and Bioreceptor Immobilization 285 8.3.2 Biosensor Based on Chitosan Nanocomposite 287 8.3.2.1 Biosensors Based on Carbon Nanomaterials?Chitosan Nanocomposite 287 8.3.2.2 Biosensors Based on Metal and Metal Oxide?Chitosan Nanocomposite 290 8.3.2.3 Biosensors Based on Quantum Dots Chitosan Nanocomposite 293 8.3.2.4 Biosensors Based on IonicLiquid Chitosan Nanocomposite 293 8.4 Emerging Biosensor and Future Perspectives 294 Acknowledgments 298 References 298 Part 3 Systematic Bioelectronic Strategies 309 9 Bilayer Lipid Membrane Constructs: A Strategic Technology Evaluation Approach 311 Christina G. Siontorou 9.1 The Lipid Bilayer Concept and the Membrane Platform 312 9.2 Strategic Technology Evaluation: The Approach 318 9.3 The Dimensions of the Membrane-Based Technology 319 9.4 Technology Dimension 1: Fabrication 322 9.4.1 Suspended Lipid Platforms 322 9.4.2 Supported Lipid Platforms 327 9.4.3 Micro- and Nano-Fabricated Lipid Platforms 331 9.5 Technology Dimension 2: Membrane Modelling 333 9.6 Technology Dimension 3: Artificial Chemoreception 336 9.7 Technology Evaluation 337 9.8 Concluding Remarks 339 Abbreviations 340 References 340 10 Carbon and Its Hybrid Composites as Advanced Electrode Materials for Supercapacitors 355 S. T. Senthilkumar, K. Vijaya Sankar, J. S. Melo, A. Gedanken and R. Kalai Selvan 10.1 Introduction 356 10.1.1 Background 356 10.2 Principle of Supercapacitor 358 10.2.1 Basics of Supercapacitor 358 10.2.2 Charge Storage Mechanism of SC 360 10.2.2.1 Electric Double-Layer Capacitor (EDLC) 360 10.2.2.2 Pseudocapacitors 361 10.2.2.3 Electrode Materials for Supercapacitors 364 10.3 Activated Carbon and Their Composites 366 10.4 Carbon Aerogels and Their Composite Materials 368 10.5 Carbon Nanotubes (CNTs) and Their Composite Materials 371 10.6 Two-Dimensional Graphene 374 10.6.1 Electrochemical Performance of Graphene 375 10.6.2 Graphene Composites 376 10.6.2.1 Binary Composites 376 10.6.2.2 Ternary Hybrid Electrode 378 10.6.3 Doping of Graphene with Heteroatom 380 10.7 Conclusion and Outlook 381 Acknowledgements 382 References 382 11 Recent Advances of Biosensors in Food Detection Including Genetically Modified Organisms in Food 395 T. Varzakas, Georgia-Paraskevi Nikoleli, and Dimitrios P. Nikolelis 11.1 Electrochemical Biosensors 396 11.2 DNA Biosensors for Detection of GMOs Nanotechnology 400 11.3 Aptamers 411 11.4 Voltammetric Biosensors 412 11.5 Amperometric Biosensors 413 11.6 Optical Biosensors 414 11.7 Magnetoelastic Biosensors 415 11.8 Surface Acoustic Wave (SAW) Biosensors for Odor Detection 415 11.9 Quorum Sensing and Toxoflavin Detection 416 11.10 Xanthine Biosensors 417 11.11 Conclusions and Future Prospects 418 Acknowledgments 419 References 419 12 Numerical Modeling and Calculation of Sensing Parameters of DNA Sensors 429 Hediyeh Karimi, Farzaneh Sabbagh, Rasoul Rahmani, and M. T. Ahamdi 12.1 Introduction to Graphene 430 12.1.1 Electronic Structure of Graphene 431 12.1.2 Graphene as a Sensing Element 431 12.1.3 DNA Molecules 432 12.1.4 DNA Hybridization 432 12.1.5 Graphene-Based Field Effect Transistors 434 12.1.6 DNA Sensor Structure 435 12.1.7 Sensing Mechanism 436 12.2 Numerical Modeling 437 12.2.1 12.2.2 Modeling of the Sensing Parameter (Conductance) Current Voltage (Id?Vg) Characteristics 437Modeling 44012.2.3 Proposed Alpha Model 44112.2.4 Comparison of the Proposed NumericalModel with Experiment 444References 44713 Carbon Nanotubes and Cellulose Acetate Composite for Biomolecular Sensing 453 Padmaker Pandey, Anamika Pandey, O. P. Pandey and N. K. Shukla 13.1 Introduction 453 13.2 Background of the Work 456 13.3 Materials and Methodology 459 13.3.1 Preparation of Membranes 459 13.3.2 Immobilisation of Enzyme 460 13.3.3 Assay for Measurement of Enzymatic Reaction 460 13.4 Characterisation of Membranes 460 13.4.1 Optical Microscope Characterisation 460 13.4.2 Scanning Electron Microscope Characterisation 462 13.5 pH Measurements Using Different Membranes 462 13.5.1 For Un-immobilised Membranes 462 13.5.2 For Immobilised Membranes 462 13.6 Conclusion 464 Reference 465 14 Review of the Green Synthesis of Metal/Graphene Composites for Energy Conversion, Sensor, Environmental, and Bioelectronic Applications 467Shude Liu, K.S. Hui, and K.N. Hui 14.1 Introduction 468 14.2 Metal/Graphene Composites 468 14.3 Synthesis Routes of Graphene 469 14.3.1 CVD Synthesis of Graphene 469 14.3.2 Liquid-Phase Production of Graphene 473 14.3.3 Epitaxial Growth of Graphene 476 14.4 Green Synthesis Route of Metal/Graphene Composites 478 14.4.1 Microwave-Assisted Synthesis of Metal/Graphene Composites 479 14.4.2 Non-toxic Reducing Agent 482 14.4.3 In Situ Sonication Method 484 14.4.4 Photocatalytic Reduction Method 486 14.5 Green Application of Metal/Graphene and Doped Graphene Composites 487 14.5.1 Energy Storage and Conversion Device 487 14.5.2 Electrochemical Sensors 490 14.5.3 Wastewater Treatment 491 14.5.4 Bioelectronics 492 14.6 Conclusion and Future Perspective 496 Acknowledgments 497 References 497

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Book SynopsisThis fifth edition of the most accessible introduction to MRI principles and applications from renowned teachers in the field provides an understandable yet comprehensive update. Accessible introductory guide from renowned teachers in the field Provides a concise yet thorough introduction for MRI focusing on fundamental physics, pulse sequences, and clinical applications without presenting advanced math Takes a practical approach, including up-to-date protocols, and supports technical concepts with thorough explanations and illustrations Highlights sections that are directly relevant to radiology board exams Presents new information on the latest scan techniques and applications including 3 Tesla whole body scanners, safety issues, and the nephrotoxic effects of gadolinium-based contrast media Table of ContentsPreface, ix ABR study guide topics, xi 1 Production of net magnetization 1 1.1 Magnetic fields 1 1.2 Nuclear spin 2 1.3 Nuclear magnetic moments 4 1.4 Larmor precession 4 1.5 Net magnetization 6 1.6 Susceptibility and magnetic materials 8 2 Concepts of magnetic resonance 10 2.1 Radiofrequency excitation 10 2.2 Radiofrequency signal detection 12 2.3 Chemical shift 14 3 Relaxation 17 3.1 T1 relaxation and saturation 17 3.2 T2 relaxation, T2* relaxation, and spin echoes 21 4 Principles of magnetic resonance imaging – 1 26 4.1 Gradient fields 26 4.2 Slice selection 28 4.3 Readout or frequency encoding 30 4.4 Phase encoding 33 4.5 Sequence looping 35 5 Principles of magnetic resonance imaging – 2 39 5.1 Frequency selective excitation 39 5.2 Composite pulses 44 5.3 Raw data and image data matrices 46 5.4 Signal-to-noise ratio and tradeoffs 47 5.5 Raw data and k-space 48 5.6 Reduced k-space techniques 51 5.7 Reordered k-space filling techniques 54 5.8 Other k-space filling techniques 56 5.9 Phased-array coils 58 5.10 Parallel acquisition methods 60 6 Pulse sequences 65 6.1 Spin echo sequences 67 6.2 Gradient echo sequences 70 6.3 Echo planar imaging sequences 75 6.4 Magnetization-prepared sequences 77 7 Measurement parameters and image contrast 86 7.1 Intrinsic parameters 87 7.2 Extrinsic parameters 89 7.3 Parameter tradeoffs 91 8 Signal suppression techniques 94 8.1 Spatial presaturation 94 8.2 Magnetization transfer suppression 96 8.3 Frequency-selective saturation 99 8.4 Nonsaturation methods 101 9 Artifacts 103 9.1 Motion artifacts 103 9.2 Sequence/Protocol-related artifacts 105 9.3 External artifacts 119 10 Motion artifact reduction techniques 126 10.1 Acquisition parameter modification 126 10.2 Triggering/Gating 127 10.3 Flow compensation 132 10.4 Radial-based motion compensation 134 11 Magnetic resonance angiography 135 11.1 Time-of-flight MRA 137 11.2 Phase contrast MRA 141 11.3 Maximum intensity projection 144 12 Advanced imaging applications 147 12.1 Diffusion 147 12.2 Perfusion 153 12.3 Functional brain imaging 156 12.4 Ultra-high field imaging 158 12.5 Noble gas imaging 159 13 Magnetic resonance spectroscopy 162 13.1 Additional concepts 162 13.2 Localization techniques 167 13.3 Spectral analysis and postprocessing 169 13.4 Ultra-high field spectroscopy 173 14 Instrumentation 177 14.1 Computer systems 177 14.2 Magnet system 180 14.3 Gradient system 182 14.4 Radiofrequency system 184 14.5 Data acquisition system 186 14.6 Summary of system components 187 15 Contrast agents 189 15.1 Intravenous agents 190 15.2 Oral agents 195 16 Safety 196 16.1 Base magnetic field 197 16.2 Cryogens 197 16.3 Gradients 198 16.4 RF power deposition 198 16.5 Contrast media 199 17 Clinical applications 200 17.1 General principles of clinical MR imaging 200 17.2 Examination design considerations 202 17.3 Protocol considerations for anatomical regions 203 17.4 Recommendations for specific sequences and clinical situations 218 References and suggested readings 222 Index 225

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Book SynopsisBiodegradable polymers have experienced a growing interest in recent years for applications in packaging, agriculture, automotive, medicine, and other areas. One of the drivers for this development is the great quantity of synthetic plastic discarded improperly in the environment. Therefore, R&D in industry and in academic research centers, search for materials that are reprocessable and biodegradable. This unique book comprises 12 chapters written by subject specialists and is a state-of-the-art look at all types of polyethylene-based biocomposites and bionanocomposites. It includes deep discussion on the preparation, characterisation and applications of composites and nanocomposites of polyethylene-based biomaterials such as cellulose, chitin, starch, soy protein, PLA, casein, hemicellulose, PHA and bacterial cellulose.Table of ContentsPreface xv 1 Polyethylene-based Biocomposites and Bionanocomposites: State-of-the-Art, New Challenges and Opportunities 1 Sigrid Luftl and Visakh. P. M. 1.1 Introduction 2 1.2 History of the Synthesis of Polyethylene: From Fossil Fuels to Renewable Chemicals 5 1.3 Commercial Significance of PE and Bio(nano) Composites 8 1.4 State-of-the-Art 10 1.5 Preparation Methods for Nanocomposites and Bionanocomposites 28 1.6 Environmental Concerns with Regard to Nanoparticles 29 1.7 Challenges and Opportunities 30 References 31 2 Polyethylene/Chitin-based Biocomposites and Bionanocomposites 43 Meriem Fardioui, Abou El Kacem Qaiss and Rachid Bouhfid 2.1 Introduction 43 2.2 Preparation of Biocomposites and Bionanocomposites 45 2.3 Characterization of Biocomposites and Bionanocomposites 50 2.4 Applications 62 2.5 Conclusions and Perspectives 64 References 65 3 Polyethylene/Starch-based Biocomposites and Bionanocomposites 69 Yasaman Ganji 3.1 Introduction 69 3.2 Polyethylene/Starch-based Composite 70 3.3 Conclusion 91 Abbreviations 92 References 93 4 Polyethylene/Soy Protein-based Biocomposites: Properties, Applications, Challenges and Opportunities 99 H. Ismail, S. T. Sam and K. M. Chin 4.1 Introduction 99 4.2 Processing of Soy Protein 101 4.3 Effect of Different Compatibilizers on Polyethylene/Soy Protein-based Biocomposites 102 4.4 Opportunity and Challenges 161 References 163 5 Polyethylene/Hemicellulose-based Biocomposites and Bionanocomposites 167 K. Sudhakar, N. Naryana Reddy, K. Madhusudhana Rao, S. J. Moloi, A. Babul Reddy and E. Rotimi Sadiku 5.1 Introduction 167 5.2 Hemicellulose Structure 170 5.3 Hemicellulose Properties 176 5.4 Hemicellulose-based Biocomposites 177 5.5 Hemicellulose-based Bionanocomposites 186 5.6 Hemicellulose Applications 190 5.7 Conclusion 191 Acknowledgment 192 References 192 6 Polyethylene/Polyhydroxyalkanoates-based Biocomposites and Bionanocomposites 201 Oluranti Agboola, Rotimi Sadiku, Touhami Mokrani, Ismael Amer, Mapula Lucey Moropeng and Munyadziwa Mercy Ramakokovhu 6.1 Introduction 202 6.2 Polyethylene/Polyhydroxyalkanoates-based Biocomposites and Bionanocomposites 202 6.3 Conclusions 255 Abbreviations 256 References 257 7 Polyethylene/Other Biomaterials-based Biocomposites and Bionanocomposites 279 A. Babul Reddy, B. Manjula, K. Sudhakar, V. Sivanjineyulu, T. Jayaramudu and E. R. Sadiku 7.1 Introduction 279 7.2 Polyethylene/Lignin-based Biocomposites and Bionanocomposites 284 7.3 Polyethylene/Alginate-based Biocomposites and Bionanocomposites 296 7.4 Polyethylene/Casein-based Biocomposites and Bionanocomposites 302 7.5 Conclusions 307 References 308 8 Studies of Polyethylene-based Biocomposites, Bionanocomposites and Other Non-Biobased Nanocomposites 315 Norshahida Sarifuddin and Hanafi Ismail 8.1 Introduction 316 8.2 Studies of Polyethylene-based Biocomposites 317 8.3 Studies of Polyethylene-based Bionanocomposites 327 8.4 Studies of Polyethylene and Other Non-biobased Nanocomposites 334 8.5 Concluding Remarks 338 References 338 9 Biodegradation Study of Polyethylene-based Biocomposites and Bionanocomposites 345 Sumana Ghosh 9.1 Introduction 345 9.2 Biopolymer-based Biocomposites 346 9.3 Biopolymer-based Bionanocomposites 347 9.4 Applications of Biopolymer-based Biocomposites and Bionanocomposites 347 9.5 Biodegradation 349 9.6 Biodegradation Study of Cellulose-based Biocomposites/Bionanocomposites 350 9.7 Biodegradation Study of Chitin-based Biocomposites/Bionanocomposites 352 9.8 Biodegradation Study of Starch-based Biocomposites/Bionanocomposites 353 9.9 Biodegradation Study of Hemicellulose-based Biocomposites/Bionanocomposites 355 9.10 Biodegradation Study of Polylactic Acid-based Biocomposites/Bionanocomposites 356 9.11 Biodegradation Study of Polyhydroxyalkanoates-based Biocomposites/Bionanocomposites 357 9.12 Conclusions 360 Acknowledgments 360 References 360 10 Polyethylene-based Bio- and Nanocomposites for Packaging Applications 365 Paula A. Zapata and Humberto Palza 10.1 Introduction 366 10.2 Polyethylene-based Nanocomposites 369 10.3 Polyethylene-based Biocomposites 383 10.4 Polyethylene-based Bionanocomposites 393 10.5 Conclusions 397 References 398 11 Properties and Utilization of Plant Fibers and Nanocellulose for Thermoplastic Composites 405 Nadir Ayrilmis, Alireza Ashori and Jin Heon Kwon 11.1 Introduction 406 11.2 Plant Fibers 407 11.3 Nanocellulose 418 11.4 Conclusions 424 References 425 12 Modification of Poly(lactic acid) Matrix by Chemically Modified Flax Fiber Bundles and Poly(ethylene glycol) Plasticizer 429 A. Arbelaiz, J. Trifol, C. Pena-Rodriguez, J. Labidi and A. Eceiza 12.1 Introduction 429 12.2 Experimental 431 12.3 Results and Discussion 433 12.4 Conclusions 442 Acknowledgments 443 References 443 Index 447

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Book SynopsisProvides a broad range of information from basic principles to advanced applications of biosensors and nanomaterials in health care diagnostics This book utilizes a multidisciplinary approach to provide a wide range of information on biosensors and the impact of nanotechnology on the development of biosensors for health care. It offers a solid background on biosensors, recognition receptors, biomarkers, and disease diagnostics. An overview of biosensor-based health care applications is addressed. Nanomaterial applications in biosensors and diagnostics are included, covering the application of nanoparticles, magnetic nanomaterials, quantum dots, carbon nanotubes, graphene, and molecularly imprinted nanostructures. The topic of organ-specific health care systems utilizing biosensors is also incorporated to provide deep insight into the very recent advances in disease diagnostics. Biosensors and Nanotechnology: Applications in Health Care Diagnostics is compTable of ContentsList of Contributors xi Preface xv Acknowledgments xvii Section 1 Introduction to Biosensors, Recognition Elements, Biomarkers, and Nanomaterials 1 1 General Introduction to Biosensors and Recognition Receptors 3Frank Davis and Zeynep Altintas 1.1 Introduction to Biosensors 3 1.2 Enzyme‐ Based Biosensors 4 1.3 DNA‐ and RNA‐Based Biosensors 5 1.4 Antibody‐Based Biosensors 7 1.5 Aptasensors 8 1.6 Peptide‐Based Biosensors 10 1.7 MIP‐Based Biosensor 11 1.8 Conclusions 12 References 13 2 Biomarkers in Health Care 17Adama Marie Sesay, Pirkko Tervo, and Elisa Tikkanen 2.1 Introduction 17 2.2 Biomarkers 18 2.2.1 Advantage and Utilization of Biomarkers 18 2.2.2 Ideal Characteristics of Biomarkers 19 2.3 Biological Samples and Biomarkers 20 2.4 Personalized Health and Point‐of‐Care Technology 22 2.5 Use of Biomarkers in Biosensing Technology 24 2.6 Biomarkers in Disease Diagnosis 26 2.7 Conclusions 29 References 30 3 The Use of Nanomaterials and Microfluidics in Medical Diagnostics 35Jon Ashley and Yi Sun 3.1 Introduction 35 3.2 Nanomaterials in Medical Diagnostics (Bottom‐Up Approach) 36 3.2.1 Carbon Nanomaterials 37 3.2.2 Metallic Nanoparticles 39 3.2.2.1 Quantum Dots 39 3.2.2.2 Magnetic Nanoparticles (Fe2O3, FeO, and Fe3O4) 41 3.2.2.3 Gold Nanoparticles 41 3.2.2.4 Silver Nanoparticles 42 3.2.2.5 Nanoshells 42 3.2.2.6 Nanocages 43 3.2.2.7 Nanowires 43 3.2.3 Polymer‐Based Nanoparticles 44 3.3 Application of Microfluidic Devices in Clinical Diagnostics (Top‐Down Approach) 45 3.3.1 Unique Features of Microfluidic Devices 45 3.3.2 Applications of Microfluidic Devices in Medical Diagnostics 46 3.3.2.1 Types of Microfluidic POC Devices 47 3.3.2.2 Benchtop Microfluidic Instruments 47 3.3.2.3 Small, Lightweight Microfluidic Devices 49 3.3.2.4 Simple Un‐instrumented Microfluidic Systems 50 3.4 Integration of Microfluidics with Nanomaterials 52 3.5 Future Perspectives of Nanomaterial and Microfluidic‐Based Diagnostics 53 References 54 Section 2 Biosensor Platforms for Disease Detection and Diagnostics 59 4 SPR‐Based Biosensor Technologies in Disease Detection and Diagnostics 61Zeynep Altintas and Wellington M. Fakanya 4.1 Introduction 61 4.2 Basic Theoretical Principles 63 4.3 SPR Applications in Disease Detection and Diagnostics 66 4.3.1 SPR Biosensors in Cancer Detection 66 4.3.2 SPR Sensors in Cardiac Disease Detection 68 4.3.3 SPR Sensors in Infectious Disease Detection 71 4.4 Conclusions 72 References 74 5 Piezoelectric‐Based Biosensor Technologies in Disease Detection and Diagnostics 77Zeynep Altintas and Noor Azlina Masdor 5.1 Introduction 77 5.2 QCM Biosensors 78 5.3 Disease Diagnosis Using QCM Biosensors 80 5.3.1 Cancer Detection Using QCM Biosensors 82 5.3.2 Cardiovascular System Disorder Detection Using Biosensors 85 5.3.3 Pathogenic Disease Detection Using QCM Biosensors 88 5.4 Conclusions 90 References 91 6 Electrochemical‐Based Biosensor Technologies in Disease Detection and Diagnostics 95Andrea Ravalli and Giovanna Marrazza 6.1 Introduction 95 6.2 Electrochemical Biosensors: Definitions, Principles, and Classifications 96 6.3 Biomarkers in Clinical Applications 102 6.3.1 Electrochemical Biosensors for Tumor Markers 102 6.3.2 Electrochemical Biosensors for Cardiac Markers 110 6.3.3 Electrochemical Biosensors for Autoimmune Disease 115 6.3.4 Electrochemical Biosensors for Autoimmune Infectious Disease 116 6.4 Conclusions 118 References 118 7 MEMS‐Based Cell Counting Methods 125Mustafa Kangul, Eren Aydın, Furkan Gokce, Ozge Zorlu, Ebru Ozgur, and Haluk Kulah 7.1 Introduction 125 7.2 MEMS‐Based Cell Counting Methods 126 7.2.1 Optical Cell Counting Methods 126 7.2.1.1 Quantification of the Cells by Detecting Luminescence 127 7.2.1.2 Quantification of the Cells via High‐Resolution Imaging Techniques 130 7.3 Electrical and Electrochemical Cell Counting Methods 131 7.3.1 Impedimetric Cell Quantification 133 7.3.2 Voltammetric and Amperometric Cell Quantification 135 7.4 Gravimetric Cell Counting Methods 136 7.4.1 Deflection‐Based Cell Quantification 136 7.4.2 Resonant‐Based Cell Quantification 138 7.4.2.1 Theory of the Resonant‐Based Sensors 138 7.4.2.2 Actuation and Sensing Methods of Resonators in MEMS Applications 140 7.4.2.3 Resonator Structure Types Used for Cell Detection Applications 145 7.5 Conclusion and Comments 149 References 151 8 Lab‐on‐a‐Chip Platforms for Disease Detection and Diagnosis 155Ziya Isiksacan, Mustafa Tahsin Guler, Ali Kalantarifard, Mohammad Asghari, and Caglar Elbuken 8.1 Introduction 155 8.2 Continuous Flow Platforms 156 8.3 Paper‐Based LOC Platforms 161 8.4 Droplet‐Based LOC Platforms 166 8.5 Digital Microfluidic‐Based LOC Platforms 169 8.6 CD‐Based LOC Platforms 172 8.7 Wearable LOC Platforms 174 8.8 Conclusion and Outlook 176 References 177 Section 3 Nanomaterial’s Applications in Biosensors and Diagnostics 183 9 Applications of Quantum Dots in Biosensors and Diagnostics 185Zeynep Altintas, Frank Davis, and Frieder W. Scheller 9.1 Introduction 185 9.2 Quantum Dots: Optical Properties, Synthesis, and Surface Chemistry 186 9.3 Biosensor Applications of QDs 187 9.4 Other Biological Applications of QDs 191 9.5 Water Solubility and Cytotoxicity 194 9.6 Conclusion 196 References 197 10 Applications of Molecularly Imprinted Nanostructures in Biosensors and Diagnostics 201Deniz Aktas‐Uygun, Murat Uygun, and Sinan Akgol 10.1 Introduction 201 10.2 Molecular Imprinted Polymers 202 10.3 Imprinting Approaches 204 10.4 Molecularly Imprinted Nanostructures 205 10.5 MIP Biosensors in Medical Diagnosis 207 10.6 Diagnostic Applications of MIP Nanostructures 210 10.7 Conclusions 212 References 213 11 Smart Nanomaterials: Applications in Biosensors and Diagnostics 219Frank Davis, Flavio M. Shimizu, and Zeynep Altintas 11.1 Introduction 219 11.2 Metal Nanoparticles 221 11.3 Magnetic Nanoparticles 226 11.4 Carbon Nanotubes 231 11.5 Graphene 235 11.6 Nanostructured Metal Oxides 242 11.7 Nanostructured Hydrogels 247 11.8 Nanostructured Conducting Polymers 254 11.9 Conclusions and Future Trends 260 References 262 12 Applications of Magnetic Nanomaterials in Biosensors and Diagnostics 277Zeynep Altintas 12.1 Introduction 277 12.2 MNP‐Based Biosensors for Disease Detection 279 12.3 MNPs in Cancer Diagnosis and Therapy 284 12.4 Cellular Applications of MNPs in Biosensing, Imaging, and Therapy 289 12.5 Conclusions 290 References 291 13 Graphene Applications in Biosensors and Diagnostics 297Adina Arvinte and Adama Marie Sesay 13.1 Introduction 297 13.2 Graphene and Biosensors 298 13.2.1 Structure 298 13.2.2 Preparation 299 13.2.3 Properties 301 13.2.4 Commercialization in the Field of Graphene Sensors 302 13.2.5 Latest Developments in Graphene‐based Diagnosis 303 13.3 Medical Applications of Graphene 303 13.3.1 Electrochemical Graphene Biosensors for Medical Diagnostics 304 13.3.1.1 Glucose Detection 304 13.3.1.2 Cysteine Detection 307 13.3.1.3 Cholesterol Detection 309 13.3.1.4 Hydrogen Peroxide (H2O2) 310 13.3.1.5 Glycated Hemoglobin 312 13.3.1.6 Neurotransmitters 312 13.3.1.7 Amyloid‐Beta Peptide 315 13.3.2 Electrochemical Graphene Aptasensors 316 13.3.2.1 Nucleic Acids 316 13.3.2.2 Cancer Cell 318 13.3.3 Optical Graphene Sensors for Medical Diagnostics 319 13.4 Conclusions 322 Acknowledgments 322 References 322 Section 4 Organ-Specific Health Care Applications for Disease Cases Using Biosensors 327 14 Optical Biosensors and Applications to Drug Discovery for Cancer Cases 329Zeynep Altintas 14.1 Introduction 329 14.2 Biosensor Technology and Coupling Chemistries 332 14.3 Optical Biosensors for Drug Discovery 335 14.4 Computational Simulations and New Approaches for Drug–Receptor Interactions 341 14.5 Conclusions 343 References 344 15 Biosensors for Detection of Anticancer Drug–DNA Interactions 349Arzum Erdem, Ece Eksin, and Ece Kesici 15.1 Introduction 349 15.2 Electrochemical Techniques 351 15.3 Optical Techniques 356 15.4 Electrochemical Impedance Spectroscopy Technique 358 15.5 QCM Technique 360 15.6 Conclusions 361 Acknowledgments 361 References 361 Index

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Book SynopsisEvidence-based Implant Treatment Planning and Clinical Protocols provides a systematic approach to making treatment decisions and performing restorative procedures. Offers a clinically relevant resource grounded in the latest research Applies an evidence-based approach to all aspects of implant dentistry, including maxillofacial prosthodontics, from planning to surgery and restoration Describes procedures in detail with accompanying images Covers all stages of treatment, from planning to execution Includes access to a companion website with video clips demonstrating procedures and the figures from the book in PowerPoint Trade Review"This book is well written and organized. The approach is evidence based, with the majority of the focus on treatment planning for implants in patients who are partially or completely edentulous. The pairing of the book with the website is very helpful to visual learners and those who have limited experience with implant placement." (Doody Enterprises 28/04/2017)Table of ContentsContributors, viForeword, viii Prologue, ix Acknowledgments, xi About the Companion Website, xii 1 The State of the Evidence in Implant Prosthodontics, 1Gary R. Goldstein 2 Systemic Factors Influencing Dental Implant Therapy, 11Steven J. Sadowsky 3 Maintenance Considerations in Treatment Planning Implant Restorations, 22Donald A. Curtis, Hamilton Le, and Roy T. Yanase 4 Three-Dimensional Radiographic Imaging for Implant Positioning, 36Anders Nattestad 5 Decision Making in Bone Augmentation to Optimize Dental Implant Therapy, 46Jaime L. Lozada, Istvan Urban, and Joseph Y.K. Kan 6 Immediate Implant Placement and Provisionalization of Maxillary Anterior Single Implants, 57Joseph Y.K. Kan, Kitichai Rungcharassaeng, and Jaime L. Lozada 7 Surgical Complications in Implant Placement, 67Paul B. Greenawalt 8 Failure in Osseointegration, 77Kumar C. Shah, S. Andrew Chapokas, and Sreenivas Koka 9 Implant Restoration of the Partially Edentulous Patient, 85Steven J. Sadowsky 10 Prosthodontic Considerations in the Implant Restoration of the Esthetic Zone, 109Ghadeer Thalji and Sandra Al-Tarawneh 11 Ceramic Materials in Implant Dentistry, 123Parag R. Kachalia 12 Cement-Retained Implant Restorations: Problems and Solutions, 134Chandur P.K. Wadhwani 13 Implant Restoration of the Growing Patient, 159Clark M. Stanford 14 Occlusion: the Role in Implant Prosthodontics, 169Avinash S. Bidra and Thomas D. Taylor 15 Evolving Technologies in Implant Prosthodontics, 184David G. Gratton 16 Implant Dentistry: Challenges in the Treatment of the Edentulous Patient, 207Steven J. Sadowsky, Howard M. Landesman, and W. Peter Hansen 17 Implant Restoration of the Maxillary Edentulous Patient, 221Nicola U. Zitzmann 18 Implant Restoration of the Mandibular Edentulous Patient, 241Steven J. Sadowsky 19 Material Considerations in the Fabrication of Prostheses for Completely Edentulous Patients, 269James A. Kelly and Thomas J. Salinas 20 Digital Alternatives in the Implant Restoration of the Edentulous Patient, 293Mathew T. Kattadiyil 21 Restoration of Acquired Oral Defects with Osseointegrated Implants, 302John Beumer, III, Karl Lyons, Jay Jayanetti, and Eric C. Sung 22 Implant-Retained Restoration of the Craniofacial Patient, 325Robert Ferguson Wright, Glenn E. Minsley, and Sun-Yung Bak 23 Peri-Implant Diseases, 349Brian Kucey and Elena Hernandez-Kucey Epilogue, 377 Index, 379

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Book SynopsisThe only book dedicated to this important area of urology, Ureteric Stenting comprehensively reviews the entire topic, providing highly specialized advice to enable outstanding clinical management of patients.Table of ContentsList of Contributors vii Foreword x Preface xi 1 Anatomy of the Human Ureter 1 2 Anatomic Variations of the Ureter 10 3 The Pathophysiology of Upper Tract Obstruction 16 4 Physiology of the Human Ureter 29 5 Etiology of Ureteric Obstruction 48 6 The Role of the Interventional Radiologist in Managing Ureteric Obstruction 55 7 Emergency Management of Ureteric Obstruction 67 8 The History and Evolution of Ureteral Stents 75 9 Ureteral Stent Materials: Past, Present, and Future 83 10 Physical Characteristics of Stents 91 11 Coated and Drug-Eluting Stents 102 12 Coated and Drug-Eluting Ureteric Stents 110 13 Ureteric Stents: A Perspective from the Developing World 118 14 Ethical Issues in Ureteric Stenting 130 15 Equipment and Technical Considerations During Ureteric Stenting 136 16 Extra-Anatomic Stent Urinary Bypass 149 17 Detour Extra-Anatomical Ureteric Stent 161 18 Tandem Ureteral Stents 175 19 Biodegradable Ureteric Stents 182 20 Metallic Ureteric Stents 192 21 Removal of Ureteric Stents 203 22 Encrustation of Indwelling Urinary Devices 215 23 Stent Migration 227 24 Health-Related Quality of Life and Ureteric Stents 238 25 Evidence Base for Stenting 264 26 Robotic Ureteric Reconstruction 278 27 Indwelling Ureteric Stents – Health Economics Considerations 287 28 Ureteric Stents: The Future 296 Index 298

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Book SynopsisA new volume in the Handbook of Sports Medicine and Science series from the International Olympic Committee, this volume Canoeing provides an accessible and comprehensive summary of the topic. Provides a concise, authoritative overview of the science, medicine and psycho-social aspects of canoeing Offers guidance on medical aspects unique to the training and coaching of canoe athletes The only book on this subject endorsed by the Medical Commission of the International Olympic Committee (IOC) and the International Canoe Federation (ICF) Written and edited by global thought leaders in sports medicine Table of ContentsList of Contributors, vi Foreword by ICF President, viii Foreword by IOC President, ix Preface, x 1 Introduction, 1Ian Mortimer and Don McKenzie 2 Biomechanics and equipment (sprint and slalom): a review of scientifically confirmed information, 12Barney Wainwright 3 The canoe/kayak athlete, 40Petra Lundström, Jorunn Sundgot Borgen, and Don McKenzie 4 Physiology of canoeing, 47Hans Rosdahl, Jose Calbet, A. William Sheel, and Robert Boushel 5 Sport psychology for canoe and kayak, 62Penny Werthner 6 Training for canoeing, 71Martin Hunter and Sylvain Curinier 7 Medical problems in canoeing and kayaking, 91Bo Berglund 8 Orthopaedic injuries in canoeing, 97Jozsef Dobos 9 Paracanoe, 106John Edwards, Anna Bjerkefors, Johanna Rosen,and Olga Tarassova 10 Exercise performance in masters canoeing athletes, 116Bo Berglund 11 Diversity in canoe sport, 122Don McKenzie and Kari‐Jean McKenzie Index, 133

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Book SynopsisShimizu''s Dermatology, Second Edition provides practical, didactic, and rapid-reference advice on diagnosis and management of the most common dermatologic conditions.Written by one of the world''s leading experts, and a best-seller in Japan where it was first published, the second edition is cohesive, richly illustrated, attractively presented, and fully revised to reflect the latest in clinical developments. This complete dermatology resource offers: Over 2,000 clinical images to aid rapid and easy diagnosis 100% clinically focused chapters describing the clinical features, classifications, pathogeneses, pathologies, treatments and lab findings of diseases Key points and tips and tricks in every chapter for practical guidance Attractive color presentation throughout, with high-quality clinical images Improve your knowledge of skin conditions and their management with this concise, user-friendly, alternative to larger refTrade Review"There are so many introductory dermatology books that it is surprising to find one that distinguishes itself from all the others. This second edition (the first edition was published 2007) achieves the perfect balance between discussing basic dermatologic principles for nondermatologists and informing readers about the complexities and concerns that seasoned dermatologists would take into consideration with regards to evaluation, diagnosis, and treatment...All in all, this is a terrific book because it addresses the major pertinent concepts for understanding dermatology...Dermatology primers have different strengths. This book does it all." (Doody Enterprises June 2017) Table of Contents1 Structure and function of the skin 1 2 Histopathology of the skin 43 3 Dermoscopy 57 4 Description of skin lesions 67 5 Diagnosis of skin diseases 81 6 Treatment of skin diseases 92 7 Eczema and dermatitis 116 8 Urticaria prurigo and pruritus 134 9 Erythema and erythroderma 145 10 Drug‐induced skin reactions and graft‐versus‐host disease 158 11 Vasculitis purpura and other vascular diseases 171 12 Collagen diseases 203 13 Physicochemical injury and photosensitive diseases 234 14 Blistering and pustular diseases 254 15 Disorders of keratinization 285 16 Disorders of skin color 325 17 Metabolic disorders 340 18 Disorders of the dermis and subcutaneous fat 363 19 Disorders of the skin appendages 387 20 Nevi and neurocutaneous syndromes 405 21 Benign skin tumors 439 22 Malignant skin tumors lymphomas and melanomas 481 23 Viral infections 528 24 Bacterial infections 556 25 Fungal diseases 576 26 Mycobacterial infections 593 27 Sexually transmitted infections 605 28 Skin diseases caused by arthropods (insects spiders crustaceans) and other noxious animals 613 Appendix: Main genodermatoses and their causative genes and proteins 626 Index 630

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Book SynopsisThe Dental Foundation Interview Guide: with Situational Judgement Tests offers an indispensable step-by-step guide to the dental foundation training application process. Explains the application and recruitment process and includes essential interview tips Offers a wealth of practice questions with detailed answers to ensure familiarity with the process Highlights the importance of professionalism, leadership and management within the dental practice Written by recent graduates who understand the pressures of the application process Table of ContentsPreface vii Acknowledgements ix 1 What is dental foundation training? 1 2 The application process 3 DF1 recruitment process 3 How to apply 4 Key dates 5 DF1 schemes – where to work 5 DF1 interview – format 9 Scotland applications 11 3 The SJT exam 13 What is an SJT? 13 Format of the exam 13 Marking format of the exam 14 4 Definitions and legalities 15 Definitions 15 Legislation for the dental team 17 Clinical governance 19 5 Important notes for revision 25 Standards for the dental team 25 Consent 26 Confidentiality 29 Complaints 31 Scope of practice 32 Continued professional development (CPD) 33 Raising concerns 34 Child protection and vulnerable adults 35 A checklist of sources to consult during revision 37 6 Practice scenarios 39 Introduction 39 Professionalism leadership and management scenarios 40 Patient communication scenarios 54 7 Situational judgement test practice questions 57 Introduction 57 Ranking-based SJTs: Questions 58 Ranking-based SJTs: Answers 86 ‘Best of three’ SJTs: Questions 111 ‘Best-of-three’ SJTs: Answers 144 8 How to write a dental CV 165 Introduction 165 Format 166 Some dos and don’ts 168 The meet and greet 168 Some useful questions to ask 168 Index 171

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Book SynopsisA large percentage of skilled dental professionals lack the tools and comfort level required to market themselves and their dental implant practices effectively As a consequence, these dental professionals miss several opportunities to help patients and grow their business. Even those who recognize the need for marketing often don't have the experience or training to do so effectively. Marketing Implant Dentistry meets this need by giving dentists the tools to better market and promote their practices and to gain case acceptance.Marketing Implant Dentistry presents proven approaches for attracting dental implant patients and demonstrates the use of successful communication skills, including verbal and visual aids. This book details multiple examples of patient friendly and professional letters for use in targeting both new implant patients and professional referral sources. Readers will learn the benefits of adopting non-traditional approaches such as hostiTable of ContentsForeword viii Introduction x 1 Visual aids and verbal skills 1 Physicians make great use of visual aids 2 Better to show empathy, not sympathy 2 Implants are worth more than replacing missing teeth 4 Everything begins with asking the right questions 4 The power of visual aids 6 Verbal skills 11 Work out the financials 13 Dental implant models 16 Elevator pitch 18 Could it be that your case presentation just sucks? 19 Implant animations 20 Leveraging your auxiliary staff for animation demos 23 Summary 24 2 Patient education seminars 25 Lasik eye surgery education seminars 26 Using patient education seminars to attract dental implant patients 27 Seminar location 28 The presentation 30 The body of your presentation 34 Presentation conclusion 43 The postpresentation process 45 Advertising your patient education seminars 47 Summary 49 3 Partnering with physicians for dental implants 51 A physician’s endorsement of you could be priceless 52 Speak in a language the physician understands 53 Unconventional methods can lead to extraordinary results 55 Targeting endocrinologists and orthopedic surgeons for patient referrals 56 Targeting the gastroenterologist doctors 58 Targeting otolaryngologists (aka ENT doctors) 61 Targeting plastic surgeons for patient referrals 63 Targeting obstetrician and gynecologists (OB/GYN) 64 Other healthcare providers to target 65 Keep your expectations realistic 67 Physicians need dental implants too 68 Comarketing efforts 69 Summary 70 4 Marketing full]arch implant dentistry in your practice 71 Tissue]borne dentures: The short]term solution 73 Targeting your denture wearers first 75 Face]to]face with the denture patient 77 Immediate load/immediate function 79 Targeting removable partial denture and fixed partial denture patients for immediate load 81 Presenting the treatment plan for immediate load 81 The failing partial]denture: Post]op examination discussion 82 Consultation with the immediate]load candidate 87 Making financial arrangements 95 Establish goals for immediate]load production 96 Summary 97 5 Implant marketing for the surgical specialist 98 Who moved my implant? 99 Meeting the needs of restorative doctor 100 Sharing case reports with restorative doctors 103 Edentulous patient implant study group 105 Target your top two to five referral sources’ patient base 112 Patients and professionals are used to direct]to]consumer advertising 114 You too should go direct to consumer 115 Strategies for going direct to consumer 116 The prosthodontist specialty 118 Role of an implant coordinator 120 Expand your geographical range 122 Reducing clinical limitations is crucial 123 Summary 126 6 Database marketing 128 Automate your data entry as much as possible 130 Querying your removable partial]denture patients for in]depth insight 131 Collecting the right data through patient surveys is crucial 133 How you structure your survey is important 135 SurveyMonkey.com: Use it! 135 Tailor your marketing efforts to match your research findings 136 Automate your marketing correspondence 137 Define your missing teeth demographics 138 The numbers don’t lie 140 Build rapport year]round 141 Target each demographic in your database for implants 142 Reactivate your inactive patients 143 Drop your buckets where you are 144 Summary 145 7 Internet presence 146 Website 147 YouTube 150 Google Adwords 152 Landing page (or squeeze page) 153 Social media 154 Rating sites 163 Summary 164 Works cited 165 Index 167

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Book Synopsis* Peer-reviewed articles from the pages of the Journal of Prosthodontics * Mix of clinical reports, research articles, and reviews .Table of ContentsPreface ix Acknowledgments xi American College of Prosthodontists Position Statement on Dental Implants xiii PART I MANAGEMENT OF THE PARTIALLY EDENTULOUS PATIENT 1 ICK Classification System for Partially Edentulous Arches 3Sulieman S. Al-Johany and Carl Andres 2 A Systematic Approach to Definitive Planning and Designing Single and Multiple Unit Implant Abutments 10Sanjay Karunagaran, Sony Markose, Gregory Paprocki, and Russell Wicks 3 The Digital One-Abutment/One-Time Concept. A Clinical Report 21Florian Beuer, Julian Groesser, Josef Schweiger, Jeremias Hey, Jan-Frederik Güth, and Michael Stimmelmayr 4 Influence of Surgical and Prosthetic Techniques on Marginal Bone Loss around Titanium Implants. Part I: Immediate Loading in Fresh Extraction Sockets 27Antoine N. Berberi, Georges E. Tehini, Ziad F. Noujeim, Alexandre A. Khairallah, Moustafa N. Abousehlib, and Ziad A. Salameh 5 A Prospective Analysis of Immediate Provisionalization of Single Implants 35Thomas J. Balshi, Glenn J. Wolfinger, Daniel Wulc, and Stephen F. Balshi 6 Technique for Removing Cement between a Fixed Prosthesis and Its Substructure 41Abdullah S. Alsiyabi and David A. Felton 7 Immediate Loading of Dental Implants in the Esthetic Region Using Computer-Guided Implant Treatment Software and Stereolithographic Models for a Patient with Eating Disorders 45Daniel F. Galindo and Caesar C. Butura 8 A Screwless and Cementless Technique for the Restoration of Single-Tooth Implants: A Retrospective Cohort Study 52Rainier A. Urdaneta, Mauro Marincola, Meghan Weed, and Sung-Kiang Chuang PART II MANAGEMENT OF THE COMPLETELY EDENTULOUS PATIENT 9 Evidence-Based Criteria for Differential Treatment Planning of Implant Restorations for the Mandibular Edentulous Patient 67Steven J. Sadowsky and Peter W. Hansen 10 Mandibular Implant Overdenture Treatment: Consensus and Controversy 77David R. Burns 11 Evidence-Based Criteria for Differential Treatment Planning of Implant Restorations for the Maxillary Edentulous Patient 87Steven J. Sadowsky, Brian Fitzpatrick, and Donald A. Curtis 12 Relevant Anatomic and Biomechanical Studies for Implant Possibilities on the Atrophic Maxilla: Critical Appraisal and Literature Review 103Paulo Henrique Orlato Rossetti, Wellington Cardoso Bonachela, and Leylha Maria Nunes Rossetti 13 A Retrospective Analysis of 800 Brånemark System Implants Following the All-on-FourTM Protocol 114Thomas J. Balshi, Glenn J. Wolfinger, Robert W. Slauch, and Stephen F. Balshi 14 Practice-Based Evidence from 29-Year Outcome Analysis of Management of the Edentulous Jaw Using Osseointegrated Dental Implants 121Matilda Dhima, Vladimira Paulusova, Christine Lohse, Thomas J. Salinas, and Alan B. Carr 15 Double Full-Arch Versus Single Full-Arch, Four Implant-Supported Rehabilitations: A Retrospective, 5-Year Cohort Study 131Paulo Maló, Miguel De Araújo Nobre, Armando Lopes, and Rolando Rodrigues 16 The Influence of Rehabilitation Characteristics in the Incidence of Peri-Implant Pathology: A Case-Control Study 140Miguel Alexandre de Araújo Nobre and Paulo Maló 17 Concepts for Designing and Fabricating Metal Implant Frameworks for Hybrid Implant Prostheses 152Carl Drago and Kent Howell 18 Complications and Patient-Centered Outcomes with an Implant-Supported Monolithic Zirconia Fixed Dental Prosthesis: 1 Year Results 166Bryan Limmer, Anne E. Sanders, Glenn Reside, and Lyndon F. Cooper 19 Prosthetic Improvement of Pronounced Buccally Positioned Zygomatic Implants: A Clinical Report 177Ataís Bacchi, Mateus Bertolini Fernandes dos Santos, Marcele Jardim Pimentel, Mauro Antonio de Arruda Nóbilo, and Rafael Leonardo Xediek Consani PART III MANAGEMENT OF PATIENTS WITH MAXILLOFACIAL DEFECTS 20 Implant-Supported Facial Prostheses Provided by a Maxillofacial Unit in a U.K. Regional Hospital: Longevity and Patient Opinions 185S.M. Hooper, T. Westcott, P.L.L. Evans, A.P. Bocca, and D.C. Jagger 21 Immediate Obturator Stabilization Using Mini Dental Implants 192Gregory C. Bohle, William W. Mitcherling, John J. Mitcherling, Robert M. Johnson, and George C. Bohle III 22 Prosthetic Reconstruction of a Patient with an Acquired Nasal Defect Using Extraoral Implants and a CAD/CAM Copy-Milled Bar 197Carolina Vera, Carlos Barrero, William Shockley, Sandra Rothenberger, Glenn Minsley, and Carl Drago PART IV IN VITRO STUDIES 23 Influence of Implant/Abutment Connection on Stress Distribution to Implant-Surrounding Bone: A Finite Element Analysis 207Marcia Hanaoka, Sergio Alexandre Gehrke, Fabio Mardegan, César Roberto Gennari, Silvio Taschieri,Massimo Del Fabbro, and Stefano Corbella 24 An In Vitro Comparison of Fracture Load of Zirconia Custom Abutments with Internal Connection and Different Angulations and Thickness: Part I 215Abdalah Albosefi, Matthew Finkelman, and Roya Zandparsa 25 Surface Characteristics and Cell Adhesion: A Comparative Study of Four Commercial Dental Implants 221Ruohong Liu, Tianhua Lei, Vladimir Dusevich, Xiamei Yao, Ying Liu, Mary P. Walker, Yong Wang, and Ling Ye PART V GENERAL CONSIDERATIONS 26 Outcomes of Dental Implants in Osteoporotic Patients. A Literature Review 237Ioanna N. Tsolaki, Phoebus N. Madianos, and John A. Vrotsos 27 Updated Clinical Considerations for Dental Implant Therapy in Irradiated Head and Neck Cancer Patients 254Takako Imai Tanaka, Hsun-Liang Chan, David Ira Tindle, Mark MacEachern, and Tae-Ju Oh 28 Implant Treatment Record Form 263Tony Daher, Charles J. Goodacre, and Steven M. Morgano Index 267

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Book SynopsisDental Practice Transition: A Practical Guide to Management, Second Edition, helps readers navigate through options such as starting a practice, associateships, and buying an existing practice with helpful information on business systems, marketing, staffing, and money management. Unique comprehensive guide for the newly qualified dentist Covers key aspects of practice management and the transition into private practice Experienced editorial team provides a fresh, balanced and in-depth look at this vitally important subject New and expanded chapters on dental insurance, patient communication, personal finance, associateships, embezzlement, and dental service organizations Table of ContentsContributors vii Preface ix About the Companion Website xi Part 1 An Introduction to the Practice Transition, Dental Practice Financial Statements, and Practice Financial Analysis 1 Chapter 1 Introduction and Overview 3David G. Dunning and Brian M. Lange Chapter 2 Financial Statements 23David O. Willis Chapter 3 Practice Financial Analysis 35David O. Willis Part 2 Ownership: Business Planning, Practice Valuation, Dental Equipment, Buying/Buying into a Practice, Starting a Practice, Financing a Practice and Business Entities 51 Chapter 4 Business Planning: Fromthe Perspective of theDentist and the Banker 53Nader A. Nadershahi, Lucinda J. Lyon, and Lisa Itaya Chapter 5 Understanding Practice Valuation 85C. Steven Wolff, DDS Chapter 6 Dental Equipment 97Mike Wacker Chapter 7 Buying/Buying into a Practice 113Nader A. Nadershahi and Lucinda J. Lyon Chapter 8 Starting a Dental Practice 133David G. Dunning, Bradley Alderman, and Tyler Smith Chapter 9 Financing a Practice 153Gavin Shea Chapter 10 Business Entities 169Arthur S. Wiederman and Ross L. Crist Part 3 Business Systems and Related Issues: Incorporating Technology, Dental Fees and Financial Policies, Dental Benefits, Appointment Scheduling, Compliance, and Embezzlement 189 Chapter 11 Incorporating Technology 191Thomas Terronez Chapter 12 Dental Fees, Fee Setting, and Financial Policies for Patients 203Robert D. Madden and Eugene Heller Chapter 13 Dental Benefits 231Kristen Strasheim, RDH, BSDH Chapter 14 Appointment Scheduling Strategies 245Dunn H. Cumby Chapter 15 Compliance with Government Regulations 275Ronda Anderson Chapter 16 Understanding Embezzlement 287David Harris Part 4 Marketing and Patient Communication 307 Chapter 17 External Marketing 309Darold Opp Chapter 18 Internal Marketing and Customer Service 323Amy Kirsch Chapter 19 Chairside Communication with Patients 337David G. Dunning and Brian M. Lange Part 5 Associateships and Dental Support Organizations 347 Chapter 20 About Associateships 349Richard S. Callan Chapter 21 Dental Support Organizations 369Rick Workman Part 6 Managing Staff: Human Resources/Compliance, Managing Dental Teams, and Staff Meetings 383 Chapter 22 Human Resources and Employment Compliance 385Tim Twigg and Rebecca Boartfield Chapter 23 Managing Dental Teams 401Amy Kirsch Chapter 24 Staff Meetings 421David Neumeister Part 7 Money Management: Insuring a Practice; and Personal Finance, Investments, and Retirement Options 443 Chapter 25 Insuring a Dental Practice 445James E. Spitsen Chapter 26 Personal Finance, Investments, and Retirement Options 471William “Dana” Webb and Brian M. Lange Index 489

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Book SynopsisAn updated and revised resource to evidence-based urology information and a guide for clinical practice The revised and updated second edition of Evidence-Based Urology offers the most current information on the suitability of both medical and surgical treatment options for a broad spectrum of urological conditions based on the best evidence available. The text covers each of the main urologic areas in specific sections such as general urology, oncology, female urology, trauma/reconstruction, pediatric urology, etc. All the evidence presented is rated for quality using the respected GRADE framework. Throughout the text, the authors highlight the most patient-important, clinical questions likely to be encountered by urologists in day-to-day practice. A key title in the Evidence-Based series, this revised and expanded edition of Evidence-Based Urology contains new chapters on a variety of topics including: quality improvement, seminoma, nonseminomatoTrade Review"This is a valuable book for all who care for urological patients. Every provider should have a foundation in evidence-based medicine and be familiar with interpreting and applying clinical knowledge to patient care. This book helps readers to achieve both. It addresses today's most relevant clinical questions in a manner that enables readers to practice evidence-based medicine skills." - Doody's Book Review, April 2019Table of ContentsPart 1 Evidence‐based methodsPhilipp Dahm 1 Searching for evidence, 3Jeanette Buckingham 2 Clinical trials in urology, 19Charles D. Scales, Jr. and David F. Penson 3 Systematic reviews in urology, 25Philipp Dahm, Shahnaz Sultan, and Jae Hung Jung 4 Rating the quality of evidence and making recommendations, 39Philipp Dahm and Shahnaz Sultan 5 Evidence‐based clinical practice guidelinesin urology, 47Steven E. Canfield 6 Understanding concepts related to health economics in urology, 53Yair Lotan and Ryan Hutchinson 7 Quality improvement in urology, 59Nima Almassi and Howard B. Goldman Part 2 General urology and stone diseaseCharles D. Scales, Jr. 8 Antibiotic prophylaxis in urological surgery, 67Roderick Clark and Philippe Violette 9 Venous thromboembolism (VTE) prophylaxis, 89Vikram Narayan and Philipp Dahm 10 Operative safety, 103Elizabeth Timbrook Brown, Bryan J. Hill, and Roger R. Dmochowski 11 Prophylaxis and treatment of urinary tract infections in adults, 113Gabrielle J. Williams, Angela C. Webster, and Jonathan C. Craig 12 Medical management of stone disease, 133Timothy Y. Tseng and Glenn M. Preminger 13 Surgical management of renal stone disease, 159Justin M. Dersch, Brandon J. Otto, and Benjamin K. Canales 14 Surgical management of ureteral stone disease, 171Aaron H. Lay, Jay D. Raman, and Margaret S. Pearle Part 3 Pediatric urologyLuis H.P. Braga 15 Prenatal hydronephrosis, 187Shawn Dason and Luis H.P. Braga 16 Cryptorchidism, 197David I. Chu and Gregory E. Tasian 17 Vesicoureteral reflux disease, 209Ruiyang Jiang and Jonathan C. Routh 18 Circumcision, 217Roderick Clark and Sumit Dave 19 Nocturnal enuresis, 235Stacy T. Tanaka 20 Management of neurogenic bladder in children with spina bifida, 243Kourosh Afshar, Mir Sohail Fazeli, and Cyrus Chehroodi 21 Wilms tumor, 251Ruiyang Jiang and Jonathan C. Routh Part 4 Prostate cancerJulio M. Pow-Sang 22 Early detection and screening for prostate cancer, 257Pim J. van Leeuwen, Monique J. Roobol, and Phillip D. Stricker 23 Molecular markers for prostate cancer, 265Pranav Sharma, Eric Webb, and Julio M. Pow‐Sang 24 Imaging of the prostate, 279Matthew J. Watson, Francesca V. Mertan, Samuel Borofsky, Arvin K. George,Abhinav Sidana,Peter L. Choyke, Peter A. Pinto, and Baris Turkbey 25 Active surveillance for localized prostate cancer, 289Nathan Perlis and Laurence Klotz 26 Surgical management of prostate cancer,297Daniel A. Barocas and Michael S. Cookson 27 Radiation therapy for clinically localized prostate cancer, 317Michelle Echevarria, Peter A. Johnstone, and Kosj Yamoah 28 Management of metastatic prostate cancer, 331Michael S. Humeniuk, Tian Zhang, Megan A. McNamara,Sundhar Ramalingam, and Michael R. Harrison Part 5 Kidney and bladder cancerRodney H. Breau 29 Treatment of superficial bladder cancer, 349Alexander Kretschmer, Alexander Karl, and Badrinath R. Konety 30 Treatment of muscle‐invasive bladder cancer, 367Justin R. Gregg and Sam S. Chang 31 Management of upper tract urothelial carcinoma, 373Ilaria Lucca, Romain Mathieu, Tobias Klatte, and Shahrokh F. Shariat 32 Metastatic bladder cancer, 383Louise Harris, Caitlin Bowen, Satish Kumar, Bernadette Coles, and Malcolm Mason 33 Treatment of localized kidney cancer, 391Luke T. Lavallée, Frédérick Pouliot, and Rodney H. Breau 34 Treatment of metastatic kidney cancer, 399Przemyslaw W. Twardowski and Robert A. Figlin Part 6 Testis and penile cancerMichael C. Risk 35 Early‐stage (stage I) seminoma, 409Sia Daneshmand and Cory Hugen 36 Advanced (stage II and III) and recurrent seminoma, 417Peter C. Black and Christian Kollmannsberger 37 Early‐stage nonseminomatous germ‑cell tumor, 427Justin T. Matulay and James M. McKiernan 38 Advanced nonseminoma, 443Michael C. Risk and Clint Cary 39 Penile cancer, 457Oliver W. Hakenberg Part 7 Female urology, trauma, and reconstructionRoger R. Dmochowski 40 Medical management of urinary incontinence in women, 467Joshua A. Cohn, Elizabeth Timbrook Brown, W. Stuart Reynolds, Melissa R. Kaufman,Roger R. Dmochowski 41 Surgical treatment of female urinary incontinence, 479Alex Gomelsky 42 Diagnosis and treatment of overactive bladder, 489Nadir I. Osman, Altaf Mangera, and Christopher R. Chapple 43 Urethral stricture disease, 497Robert A. Goldfarb and Sean P. Elliott 44 Genitourinary trauma, 503Paul Chung and Bryan B. Voelzke Part 8 Male LUTS and sexual dysfunctionJohn M. Hollingsworth 45 Medical management of benign prostatic hyperplasia, 511Paholo G. Barboglio Romo and John M. Hollingsworth 46 Surgical management of lower urinary tract symptoms secondary to benign prostatic hypertrophy, 527Derek J. Lomas and Amy Krambeck 47 Chronic prostatitis/chronic pelvic pain syndrome (NIH category III), 539Giuseppe Magistro and Florian M.E. Wagenlehner 48 Management of erectile dysfunction, 545Hunter Wessells 49 Update on treatment of bladder pain syndrome: does anything work? 555Yahir Santiago‐Lastra, Ann Oldendorf, and J. Quentin Clemens 50 Male infertility, 561Bryan Hinck, Ashok Agarwal, Fnu Deepinder, and Edmund S. Sabanegh, Jr. 51 Premature ejaculation, 569Josip Vukina, J. Abram McBride, Culley C. Carson, and R. Matthew Coward Index 579

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Book SynopsisThe first guide to identifying and assessing changes following urologic surgerywith follow-up protocols What is the normal appearance of a kidney after radio frequency ablation of a tumor and what does a local recurrence look like? How does the urine flow down the ureters after a trans-uretero-ureterostomy? What is the normal appearance of the urinary tract after a cystoplasty? Most clinicians would be hard-pressed to provide answers to such fundamental questions concerning post-surgical anatomy and physiology, and equally challenged to find evidence-based information on the subject. Most of the literature in radiology and urologic surgery is orientated towards diagnosis and disease management. Although this often includes complications and outcomes, the clinician is often in the dark as to the anatomical and physiological changes that follow successful treatmentespecially in cases involving conservative or reconstructive surgery. To rectify this, the editors inTable of ContentsList of Contributors xiiiAcknowledgements xv Introduction 1 Christopher Woodhouse and Alex Kirkham 1 Subtotal Nephrectomy and Tumour Ablation 5 David Nicol, Alison Elstob, Christopher Anderson, and Graham Munneke Introduction 5 Procedures 5 Partial Nephrectomy 5 Early Imaging 6 Late Imaging 7 Ablative Therapies 10 Complications 13 Successful Tumour Ablation 14 Treatment Failure 15 Surveillance 18 Follow-up Imaging 18 Partial Nephrectomy 18 Ablative Therapies 19 Surveillance 19 Conclusions 19 References 20 2 Renal Transplantation 23 Rhana H. Zakri, Giles Rottenberg, and Jonathon Olsburgh Introduction 23 The Role of Ultrasound Imaging 23 Vascular Complications 23 Transplant Renal Artery Stenosis 23 Transplant Renal Vein Thrombosis 25 Transplant Renal Artery Thrombosis 26 Arteriovenous Fistula 27 Follow-up 27 Urological Complications 27 Ureteric Complications 28 Anastomotic Urinary Leak or Urinoma 28 Missed Duplex Transplant Ureter 29 Ureteric Stenosis 30 Transplant Ureteric Reflux 30 Bladder Complications 30 Urinary Fistulae 30 General Complications 31 Lymphocoeles 31 Renal Transplant Stone Disease 31 Renal Transplant Trauma 32 Oncological Complications 32 Transplant Renal Cell Carcinoma 32 Transplant Ureteric Transitional Cell Carcinoma 33 Conclusions 33 References 34 3 Imaging After Endo-urological Stone Treatment 37 Daron Smith and Clare Allen Introduction 37 The Procedures 37 Conservative Management 37 Ureteric Stones: Results and Complications 41 Extracorporeal shock wave lithotripsy 41 Ureteroscopy 41 Renal Stones: Results and Complications 44 Flexible Ureterorenoscopy 44 Percutaneous Surgery 46 Complications and Follow-up 48 Residual Fragments After ESWL, URS, FURS and PCNL 48 Radiation Exposure for Patients with Stones 53 References 54 4 Pelvi-ureteric Junction Reconstruction 57 Mohamed Ismail and Hash Hashim Introduction 57 Antenatal Hydronephrosis 57 Pathophysiological Effect of True Pelvi-ureteric Obstruction 58 Physiological and Anatomical Changes in the Kidney Following Pyeloplasty 59 Incidental PUJO in adults 61 Long-term Follow-up 62 Conclusions 63 References 64 5 Retroperitoneal Fibrosis 67 Paul Scheel and Bruce Berlanstein Introduction 67 Available Treatments 67 Medical Therapy 67 Surgical Treatment 69 Follow-up 70 Imaging 70 Stent Removal 70 Complications 71 Stent-related Complications 71 Hydrocoeles 73 Long-term Follow-up 73 Recurrent Disease 74 References 75 6 Urinary Diversion 77 Christopher Woodhouse and Alex Kirkham Introduction 77 The Procedures 77 Clinical Follow-up of Ileal Conduits 78 Postoperative Imaging 78 The ‘Loopogram’ 78 Ultrasound 81 Nephrostomy and Antegrade Imaging 83 Monitoring of Asymptomatic Patients 83 Management of Bacteriuria and Sepsis 84 References 85 7 Ureteric Reconstruction and Replacement 87 Christopher Woodhouse and Aslam Sohaib Introduction 87 Procedures 87 Stents and Nephrostomies 87 Uretero-pyelostomy 87 Uretero-calycostomy 88 Trans-uretero-ureterostomy 88 Ureteric Re-implantation 88 Autotransplantation 90 Intestine 90 Complex Lower Urinary Tract Reconstruction 90 Other Materials and Experimental Techniques 90 Clinical Follow-up and Complications 91 Stents and Nephrostomies 91 Reconstruction with Urothelium 94 Autotransplantation 95 Intestine 96 References 98 8 Conservative and Reconstructive Bladder Surgery 101 Pardeep Kumar Introduction 101 Extravasation 101 Bladder Perforation 101 Reconstruction Following Ureteric Injury and Partial Cystectomy 103 The Irradiated Bladder 106 Complications After Posterior Exenteration 106 Conclusions 107 References 107 9 Bladder Augmentation in Children 109 Paddy Dewan and Padma Rao Introduction 109 The Procedures 109 Augmentation with Ileum or Colon 109 Gastrocystoplasty 109 Seromuscular Cystoplasty 109 Auto-augmentation 110 Uretero-cystoplasty 110 Clinical Follow-up 111 Postoperative Imaging 113 Complications of Enterocystoplasty 115 Metabolic and Electrolyte Disorders 115 Stones 115 Perforation 117 Neoplastic Progression 118 Unique Complications of Gastrocystoplasty 119 Hypochloraemic Metabolic Alkalosis 119 Hypergastrinaemia 119 Haematuria-Dysuria Syndrome 120 Changes Over Time 120 References 121 10 Radiology and Follow-up of the Neobladder 125 Richard Hautmann and Bjoern G. Volkmer Introduction 125 The Procedure 125 Radical Cystectomy in Females 125 Radical Cystectomy in Males 125 The Neobladder 125 Postoperative Imaging 126 Clinical Follow-up 127 Clinical Examination 127 Bladder and Urine Investigations 128 Renal Investigations 128 Oncologic Follow-up Specific to the Neobladder 132 Local Recurrence 132 Secondary Tumour Growth in Urinary Diversions for Benign Disease 134 Complications 135 Complications up to 90 Days 135 Long-term Complications 135 Changes Over Time 136 Reservoir Control 136 Incontinence 136 Voiding Failure (Hypercontinence) 136 Metabolic Changes (see also Chapter 11) 138 References 138 11 General Consequences of Lower Urinary Tract Replacement and Reconstruction 141 Christopher Woodhouse and Alex Kirkham Introduction 141 Reservoirs 141 The Stomach 141 Ileum 141 Gastrointestinal Consequences 141 Storage Consequences 143 Colon 143 Gastrointestinal Consequences 143 Storage Consequences 143 Rectum 145 Continence (Mainz II) 146 Anastomotic Cancer 147 Urodynamic Findings 149 Stones 149 Renal Function 151 Perforation 151 Histological Changes 153 Infection 155 Neoplasia 156 Urine Testing for Pregnancy 157 The Conduit and Continence 157 References 158 12 Surgery on the Benign Prostate 163 Doug Pendse and Mark R. Feneley Introduction 163 Procedures 163 Outcomes and Complications 165 Postoperative Failure to Void 166 Continued Failure to Void or Unsatisfactory Voiding 166 Sexual Function 168 Incontinence 170 Stricture 170 Unexpected Malignancy 171 Changes Over Time 171 References 172 13 Imaging After Treatment of Prostate Cancer 177 Alex Kirkham Introduction 177 Appearances After Radical Prostatectomy 177 Residual Tumour After Radical Prostatectomy 179 The Prostate After Ablative Therapies 179 Early Appearances 180 Early Complications 181 Appearances at 2–5 Months 182 Appearances at 6 Months: Assessing Residual and Recurrent Tumour 182 Nuclear Medicine Studies 184 A Schedule for Follow-up 184 References 184 14 Urethroplasty 189 Simon Bugeja, Clare Allen, and Daniella E. Andrich Introduction 189 Pericatheter Urethrogram 189 Ascending and Descending Urethrography 190 Radiological Appearance After Different Types of Urethroplasty 191 Traumatic Strictures 192 Idiopathic Bulbar Strictures 193 Penile Urethroplasty 193 Use of Ultrasound in Urethroplasty Follow-up 194 Follow-up After Urethroplasty 196 Radiological Appearance and Surgical Management of Recurrent Strictures After Urethroplasty 197 References 198 15 The Postoperative Appearance and Follow-up of Urinary Tract Prostheses 201 Alex Kirkham Introduction 201 Penile Prostheses 201 Normal Appearance and Imaging Techniques 201 Problems of Positioning and Length 203 Artificial Urinary Sphincters 204 Disorders of Function and Position 205 InfectioninImplantedDevices 206 Metallic Stents 208 References 208 Index 211

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Book SynopsisBasic Guide to INFECTION PREVENTION AND CONTROL IN DENTISTRY A practical step-by-step guide for all members of the dental team Thoroughly updated, this new edition ensures all members of the dental team are up to speed on the practical aspects of infection prevention and control. It provides step-by-step guidance on the safe running of a dental practice, clear and concise explanations of the key issues and concepts, an overview of the evidence base, and coverage of legal and regulatory issues about which all staff members need to be aware. With more colour photographs and illustrations than the first edition, it also includes appendices full of useful practical and clinical information, and a companion website offering helpful instructional videos and self-assessment questions. Key topics include communicable diseases, occupational health and immunization, sharp safe working, hand hygiene, personal protective equipment, disinfection of dental instrumenTrade Review“This is a reputable source of infection control and prevention protocols, and this update is necessary to maintain current guidelines on infection control. The book can be used as an additional resource for U.S.-based practices, but it may not be suitable as the sole book because some information is pertinent only to U.K. practice. The book is very thorough if used for proper practice guidelines, but more detail may be necessary based on individual practices” Maria Prassas, RDH, MEd, MOT, University of Illinois at Chicago College of Dentistry on behalf of Doody’sTable of ContentsForeword viii Preface ix Acknowledgements x About the companion website xi 1 Essentials of infection control 1 Why do we need infection control in dentistry? 1 Relative risk and risk perception 2 Risk assessment and the management decision‐making process 3 How to perform a risk assessment in a dental practice 4 Hierarchy of risk management control 6 Infection control and the law 7 Legal acts under which dental practice is conducted 8 Published standards and guidance 12 Team approach to prevention of infection 13 2 Communicable diseases in the dental surgery 16 How infections are spread 16 Reservoirs and sources of infection 18 Infectious diseases by route of infection in dentistry 19 Infectious disease by route of transmission in the dental surgery 20 Emerging and re‐emerging pathogens 28 3 Occupational health and immunization 34 Occupational health hazards 34 Building a culture of safety 35 Organizing staff health in a dental practice 37 Immunization requirements for dentistry 39 Protecting women of childbearing age 39 Occupational vaccines to protect against hepatitis and TB 43 Health checks and the consequences of blood‐borne virus infection 46 Health clearance 47 Duty of care to patients 50 4 Sharp safe working in the dental surgery 53 Why sharps prevention is important 53 When do sharps injuries occur? 55 Preventable sharps injuries 56 How to avoid a sharps injury 56 Managing sharps injuries and splashes 60 Occupational health risk assessment for BBV exposure 62 Management of hepatitis C exposures 62 Postexposure prophylaxis for HIV and hepatitis B 64 Recording of sharps injuries 66 Clinical governance and accident risk assessment 66 5 Hand hygiene 68 Hands as a source of infection 68 Hands as a source of hospital‐acquired infection 69 Hand hygiene and teamworking 70 Hand hygiene technique 76 Hand care and prevention of dermatitis 82 6 Personal protection for prevention of cross‐infection 85 Why we wear personal protective equipment 85 The role of gloves 86 Choosing a suitable glove for the task 88 Managing an allergy to NRL gloves 88 Managing latex allergies in patients 90 Masks and when to use them 91 Protective eyewear and visors 95 Protection during cardiopulmonary resuscitation 97 Tunics and uniforms 99 Protective barriers – plastic aprons and surgical gowns 102 7 Sterilization and disinfection of dental instruments 105 Decontamination cycle 105 Why has cleaning become so important? 106 Legal requirements and technical standards for decontamination 107 Where should instrument decontamination take place? 110 Design of dedicated decontamination units 110 Purchasing of dental equipment 117 Cleaning of dental instruments 118 Disinfection of dental handpieces 121 Mechanical cleaning with an ultrasonic bath 124 Thermal washer disinfectors 126 Instrument inspection 130 Dental instrument sterilization 130 Suitability of sterilizer for different loads 130 Sterilizer installation and validation 131 Steam purity and maintenance of water reservoir chamber 132 How do you know your sterilizer is working? 133 Loading the sterilizer 138 Storage of wrapped and unwrapped instruments 138 Single‐use items 142 Variant CJD and rationale for single‐use items 144 Disinfection of heat‐sensitive equipment and hard surfaces 144 Disinfection of dental impressions 146 8 Dental surgery design, surface decontamination and managing aerosols 148 Dental surgery design 148 Survival of microbes on surgery surfaces 153 General cleaning 154 Surface decontamination in the dental surgery 156 Management of aerosols and splatter 162 Managing large blood or body fluid spillages 164 9 Management of dental unit waterlines 167 What are biofilms? 167 Risk to staff and patient health from dental unit waterlines 168 Methods to reduce the biofilm 173 Control of legionellae in the dental practice water supply 180 10 Healthcare waste management 182 Legislation on hazardous waste disposal 182 Types of waste 184 What is hazardous waste? 185 Clinical waste segregation and classification 189 Amalgam waste and installation of amalgam separators 193 Mercury in the environment 193 Disposal and handling of hazardous waste in the surgery 195 Safe handling of clinical waste prior to disposal 197 Bulk storage of waste for collection 197 Transport of hazardous waste 198 Benefits of waste segregation 198 11 Transport and postage of diagnostic specimens, impressions and equipment for servicing and repair 201 Legal framework 201 Collecting specimens 202 Transport of specimens to the laboratory 203 Transport restrictions 204 Fixed pathological specimens 205 Transporting impressions 206 Equipment to be sent for service or repair 206 Appendix 208 Table A.1 Daily infection control clinical pathway 208 Table A.2 Decontamination methods for specific instruments and items of dental equipment 211 Table A.3 Examples of hand and hard surface disinfectants and dental unit waterline biocides 214 Index 217

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Book SynopsisComprehensive in scope, Aesthetic Orthognathic Surgery and Rhinoplasty presents orthognathic surgery from an aesthetic perspective, encompassing analysis, diagnosis, treatment, 3D virtual planning, and adjunctive procedures. Easily accessible clinical information presented in a concise and approachable formatWell-illustrated throughout with more than1,000 clinical photographsIncludes access to a companion website with videos of surgical proceduresTable of ContentsList of Contributors vii Foreword I ix Foreword II xi Foreword III xiii Foreword IV xv Foreword V xvii Preface xix Acknowledgements xxi About the Companion Website xxiii 1 Introduction to Aesthetic Orthognathic Surgery and Rhinoplasty 1 2 Assessment and Evaluation in the Aesthetic Orthognathic Patient 15 3 Orthodontic Considerations in Orthognathic Surgery 35 4 3D Analysis, Planning, and Model Surgery 53 5 Convex Facial Profiles, Class II Skeletal Problems 77 6 Concave Facial Profiles, Class III Skeletal Problems 97 7 Anterior Open Bite 117 8 Width and Transverse Problems 145 9 Facial Asymmetry 175 10 Midface and Orbitozygomatic Aesthetics 213 11 Smile Aesthetics 253 12 Chin and Submental Aesthetics 289 13 Rhinoplasty: Evaluation and Workup 331 14 Rhinoplasty Techniques: The Nasal Dorsum, Midvault, Septum, and Osteotomies 349 15 Rhinoplasty Techniques: Control of Tip, Ala, and Tripod Complex 381 16 Nasal Considerations and Orthognathic Surgery 421 17 Rhinoplasty and Orthognathic Surgery 447 18 Rhinoplasty Technique 489 19 Orthognathic Technique: Le Fort I and Bilateral Sagittal Split Osteotomy (BSSO) 505 20 Osseous Genioplasty 517 21 Submental Liposuction 535 22 Fat Grafting 547 23 Alloplastic Facial Augmentation 559 24 Anesthesia for Orthognathic Surgery and Rhinoplasty 573 25 Operative Preparation and Setup for Aesthetic Orthognathic Surgery and Rhinoplasty 587 26 Postoperative Care and Considerations 603 Index 613

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Book SynopsisDecision Making in Dental Implantology: Atlas of Surgical and Restorative Approaches offers an image-based resource to both the surgical and restorative aspects of implant therapy, presenting more than 2,000 color images with an innovative case-by-case approach. Takes a highly pictorial approach to all aspects of implant dentistry Discusses both the surgical and restorative aspects of implant therapy in a single resource Describes a wide range of clinical scenarios likely to be encountered in daily practice Covers anterior, posterior, and full-mouth restorations Presents more than 2,000 color images showing the basic concepts and clinical cases Table of ContentsForeword vii Decision Making in Dental Implantology ix Preface xi About the Authors xiii 1 Current Status of Clinical Practice with Dental Implants: An Evidence-Based Decision Making Overview 1 This chapter presents general aspects to be used in clinical practice with dental implants based on the most relevant up-to-date themes for implantology and other fields of dentistry. Also descriptions on the evidence quality rating/strength of recommendation of procedures proposed by the US Preventive Services Task Force (USPSTF) adapted by the American Dental Association are detailed. 2 Treatment Planning for Bone Defects in the Alveolar Ridge 23 This chapter provides details on the characteristics of the mostfrequent osseous defects the use of bone substitutes/grafting materials for bone filling and the mechanisms/dynamics of osseous repair. 3 Treatment of Esthetic Areas 43This chapter details the rational and clinical use of different treatment modalities in esthetically compromised areas. Cases 1–12. 4 Treatment of Posterior Areas 123 This chapter is exclusively dedicated to the presentation of clinical treatment alternatives for the posterior sites of the mandible and maxilla. Cases 13–27. 5 Implant-Supported Rehabilitation of Completely and Partially Edentulous Patients 205 This chapter is explains the role of certain phases of performing successful implant-supported oral rehabilitation.Cases 28–35. 6 Multidisciplinary Decision Making: The Complexity of Some Potential “Real World” Clinical Scenarios 325This chapter presents offers suggestions for the multidisciplinary construction of treatment approaches for cases presenting high esthetical and functional complexity. These therapies are based on the best evidence available on clinicians’ skills and patients’ desires. Cases 36–41. Index 407

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Book SynopsisHow to Survive Dental Performance Difficulties offers an authoritative guide for successfully navigating and overcoming dental performance issues. Offers a practical guide for preventing and overcoming dental performance issuesHighlights case studies of dental professionals who have direct experience of being referred for fitness to practise issuesIncludes information on the support available to dental professionals, the requirements that need to be met, and how to meet themContains information on the effective use of evidence, improvement practice tools such as personal development plans, continuing professional education, reflective diaries, and auditsOffers guidance on how to increase self-awareness and insight Table of ContentsForeword, ix Acknowledgements, xi Abbreviations, xiii Chapter 1 The basics of performance, 1 Introduction, 1 What is performance? 3 What is poor performance? 6 Fitness to practise, 9 Red door/green door, 10 Chapter 2 Background and contributory factors: How performance issues can arise, 13 Introduction, 13 Pressures on dentists, 14 Factors that underpin poor performance, 15 Chapter 3 Professionalism, 27 What is professionalism? 27 What does professionalism encompass? 30 How should a professional behave? 30 Societal expectations of professionals, 31 Character, 32 Building blocks of character, 33 Ethical frameworks within which professionals operate, 34 How does character relate to professionalism? 36 Tests of integrity, 36 Virtue ethics, 37 Honesty and dishonesty, 38 Communication, 42 Criminal record, convictions and cautions, 43 Scotland, 45 Protected conviction or caution, 45 Chapter 4 Regulation of dentistry and dental professionals, 48 Regulation, 48 General Medical Council, 49 General Pharmaceutical Council, 50 General Dental Council, 50 Registration, 51 NHS England, 52 Care Quality Commission, 53 Healthcare Inspectorate Wales, 54 Scotland, 54 Northern Ireland, 55 Professional Standards Authority, 56 Regulation of Dental Services Programme Board, 57 Health and Safety Executive, 58 Medicines and Healthcare Products Regulatory Agency, 59 Right‐touch regulation, 60 Chapter 5 Organisations that play a supporting role, 63 Specialist indemnity providers, 63 Educational support, 64 Health support, 67 Mentoring/professional support, 68 Advisory support, 69 Conclusion, 70 Chapter 6 The anatomy of a fitness to practise case, 72 Introduction, 72 Fitness to practise, 74 General Dental Council, 74 Fitness to practise process, 75 Interim Orders Committee, 77 Investigating Committee, 77 Practice Committees, 78 Sanctions, 78 Convictions/cautions, 82 Analysis, 83 Erasure, 86 Conclusion, 91 Chapter 7 The registrant’s journey, personal statements and case studies, 93 How it can begin, 94 The Hero’s Journey, 95 Case studies, 101 Stages of change or grief, 111 Taking a preventive approach, 113 Chapter 8 Building self‐awareness and insight, 115 Self‐awareness, 116 Insight, 116 Learning styles, 119 Tools to deepen self‐awareness, 124 Conclusion, 138 Chapter 9 Tools that can help, 140 Personal development plan, 141 Peer review, 144 Professional discussion and dialogue, 144 Case studies and presentations, 145 Clinical audit, 146 Staff meetings, 148 Patient surveys (feedback), 148 360° multisource feedback, 150 Standards, national guidelines, 151 Working with a mentor, 151 Working with a coach, 152 Appendix A Personal development plan template, 154 Appendix B Patient engagement questionnaire, 156 Appendix C Influencing skills questionnaire – 360° colleague feedback, 157 Chapter 10 Supporting colleagues who struggle, 160 Being non‐judgemental, 160 Listening, 160 Paraphrasing, 161 Questioning, 161 Guiding, 161 Reflective practice/writing and learning, 161 Working one to one, 172 Force field analysis, 176 Neurological levels, 177 Conclusion, 181 Index, 183

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Book SynopsisDental Management of the Pregnant Patient is the first book to focus on treating dental patients during pregnancy. The first book to compile all of the knowledge for managing pregnant patients into a single sourceOffers a comprehensive approach to the physiological changes in pregnancy, clinical considerations for treating pregnant patients, and discussion of medical emergenciesCovers medications, oral disease, tumors, trauma, management of gynecological emergencies, and moreTable of ContentsPreface xi Acknowledgments xiii List of Contributors xv 1 Ethical Issues in the Treatment of the Pregnant Patient 1Christos A. Skouteris References 3 Further Reading 3 2 Physiologic Changes and Their Sequelae in Pregnancy 5Christos A. Skouteris Cardiovascular 5 Respiratory 6 Hematologic 8 Gastrointestinal 10 Genitourinary 12 Endocrine 14 Immunologic 15 Dermatologic 16 Musculoskeletal 17 Psychologic and Behavioral Changes 17 References 18 Further Reading 19 3 Implications of Physiologic Changes in the Dental Management of the Pregnant Patient 25Christos A. Skouteris Cardiovascular Changes: Management Considerations 25 Respiratory Changes: Management Considerations 25 Hematologic Changes: Management Considerations 26 Gastrointestinal Changes: Management Considerations 27 Genitourinary Changes: Management Considerations 28 Endocrine Changes: Management Considerations 28 Immunologic Changes: Management Considerations 29 Dermatologic Changes: Management Considerations 29 Musculoskeletal Changes: Management Considerations 30 Psychologic and Behavioral Changes: Management Considerations 31 Reference 31 Further Reading 31 4 General Principles for the Comprehensive Treatment of the Pregnant Patient 33Christos A. Skouteris Recording of Pregnancy Status before Treatment 33 Diagnostic Imaging Modalities in Pregnancy 34 Medications, Substance Abuse, and Their Implications in the Dental Management of the Pregnant Patient 38 Procedural Sedation (Oral, N2O, Intravenous) 57 General Anesthesia 60 References 64 Further Reading 65 5 Dental and Oral Diseases in Pregnancy 71Christos A. Skouteris Prenatal Counseling and Prevention 71 Further Reading 73 6 Dental, Oral, and Maxillofacial Diseases and Conditions and Their Treatment 75 Treatment of Dental Disease 75Benjamin Craig Cornwall Odontogenic Oral and Maxillofacial Infections in Pregnancy 85Kyriaki C. Marti Benign Diseases and Conditions 90Christos A. Skouteris Management of Oral and Maxillofacial Malignancy in Pregnancy 93James Murphy and Brent B. Ward Management of Oral and Maxillofacial Trauma in Pregnancy 100Igor Makovey and Sean P. Edwards References 106 Further Reading 106 7 Postnatal Considerations 113Kyriaki C. Marti Medical Contraindications to Breastfeeding 113 Breastfeeding and Infant Oral Health 113 Procedures and Medications During Breastfeeding 115 References 121 Further Reading 122 8 Basic Life Support (BLS) and Advanced Cardiac Life Support (ACLS) in Pregnancy 125Kyriaki C. Marti Cardiac Arrest in Pregnancy 125 BLS 125 ACLS 126 Further Reading 128 9 Obstetric]Gynecologic Emergencies 129Christos A. Skouteris Hypertensive Disorders of Pregnancy 129 Abdominal Pain in Pregnancy 131 Vaginal Bleeding in Pregnancy 134 Labor and On]Scene Delivery 135 Further Reading 142 Appendices 143 Appendix 1 Cardiovascular Changes 145 Appendix 2 Cardiovascular Changes 146 Appendix 3 Respiratory Changes 147 Appendix 4 Hematologic Changes 148 Appendix 5 Gastrointestinal Changes 149 Appendix 6 Genitourinary Changes 150 Appendix 7 Endocrine Changes: Insulin Gestational Activity 151 Appendix 8 OB-GYN Emergencies 152 Appendix 9 OB-GYN Emergencies 153 Appendix 10 OB-GYN Emergencies 154 Appendix 11 Most Important Physiologic Changes Per Trimester of Pregnancy 155 Appendix 12 Management of Oral Squamous Cell Carcinoma in Pregnancy 156 Appendix 13 Management of Oral and Maxillofacial Trauma in Pregnancy 159 Reader’s Self]Assessment Quiz 161 Index 169

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Book SynopsisQuick Reference to Dental Implant Surgery offers busy practitioners quick access to all the essential information needed for successful dental implant surgery from case selection to radiographic examination, scrub-in to post-operative care.Table of ContentsAbout the Author xi Preface and Introduction xiii Case Selection and Diagnosis 1 Part A: Medical Consideration in Implant Dentistry 1 1 Commonly Ordered Blood Tests in Implant Dentistry 1 2 ASA Classifications 3 3 Medical Conditions 4 4 Recommendations for Medical Consideration in Implant Dentistry 6 Part B: Radiographic Examination and Imaging Modalities 8 1 Imaging Strategies 8 2 Radiographic Examination and Imaging Modalities 12 3 Principles of Imaging for Dental Implant Assessment, with Recommendations 15 Part C: Surgical Stents 20 1 SurgicalStentTypes 20 2 Comparison of Surgical Stents 24 3 Recommendations 25 References 25 Surgical Principles and Protocols 27 Part A: Scrubbing and Gowning 27 1 Preparation Prior to Surgical Scrub 27 2 Surgical Scrubbing Methods 27 3 Steps for Surgical Scrubbing 28 4 DryingtheHands 28 5 Gowning 28 6 De-gowning 30 7 Recommendations 30 Part B: Surgical Report 30 1 Principles 30 2 Recommendations 30 Part C: Commonly Used Medications in Implant Dentistry 31 1 Pain Management 31 2 Antibacterial Infection 32 3 Sinus Bacterial Infection 32 4 Xerostomia 33 5 Recommendations 35 References 35 Surgical Treatment 37 Part A: Immediate Implants 37 1 Classification 37 2 Procedure 39 3 General Advantages and Disadvantages 39 4 Complications and Treatment 40 5 Immediate Loading 40 6 Immediate Loading: When To? 40 7 Recommendations 40 Part B: Sinus Augmentation 43 1 MaxillarySinusAnatomy 43 2 Anatomical Considerations 44 3 Procedure Steps 44 4 Recommendations for Complications 47 Part C: Ridge Augmentation 47 1 Soft Tissue Augmentation 47 2 OnlayGrafts 51 3 Titanium Straps, Cores, and Screws 51 4 TitaniumMesh, Distraction Osteogenesis, J Block, and Ridge Expansion 55 5 Membranes 55 6 Recommendations 56 Part D: Extraction Socket Preservation 56 1 Advantages 56 2 Steps for Good Extraction Socket Development 57 3 Complications 57 4 Recommendations 57 Part E: Suture Materials 58 1 Monofilament and Multifilament Sutures 58 2 Absorbable and Non-absorbable Sutures 59 3 Natural and Synthetic Sutures 59 4 Recommendations 60 References 61 Corrective Implant Surgery 63 Part A: Clinical Recommendations for the Prevention and Treatment of Peri-implant Disease 63 Part B: Peri-implantitis Treatment Recommendations 64 References 71 Errors and Complications 73 Part A: Diagnosis of Complications 73 Part B: Surgical Errors 73 1 Early Implant Failure 73 2 Late Implant Failure 74 Part C: Prosthetic Errors 74 Part D: The Checklist 74 1 Basic Implant Placement 74 References 75 Communication 77 Part A: Sample Consents 77 1 Endosseous Implant Consent 77 2 Maxillary Sinus Augmentation Consent 81 3 Conscious Sedation Consent 83 4 Dental Extraction Consent 84 5 Ridge Augmentation Consent 86 6 Bisphosphonates Consent 88 7 BiopsyConsent 89 8 Blank Consent Form 90 9 Gingivectomy Consent 91 10 Gingival Augmentation Consent 92 Part B: Sample Surgical Report 94 Part C: Sample Postoperative Instructions and How to Clean Implants 95 Part D: Sample Patient Letters 98 Part E: Sample Letters to Physicians 99 Part F: Sample Letters to Referring Dentists 99 Index 101

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Book SynopsisAn accessible, one-stop guide to getting the most out of dental photography in clinical practice Dental photography is an increasingly important part of dental care in general practices, hospitals, and specialist clinics. The uses of dental photographs are numerous, such as monitoring treatment outcomes, educating patients, promoting services, and providing evidence for litigation or regulatory purposes. Essentials of Dental Photography is a user-friendly guide to incorporating dental photographs into daily practice. Containing real-world advice and proven techniques, this book helps clinicians understand and apply the fundamental principles of dental photography. Accessible chapters cover every major aspect of dental photography and answer the most common questions asked by clinicians. Step-by-step instructions show readers how to select the correct photographic and dental equipment, setup equipment for a variety of dental procedures, process images using photo-editing software, anTable of ContentsForeword xi Preface xiii Acknowledgments xv Section 1 Equipment and Concepts 1 1 Photographic Equipment 3 Cameras 4 Sensors 6 Resolution 9 Sensor Speed or ISO 13 Sensor Cleaning 13 Colour (Bit) Depth 15 White Balance 16 Focusing 16 External Flash 17 Remote Shutter Release 17 Lenses 17 Lighting 19 Supports 23 Other photographic items 25 References 25 2 Dental Armamentarium and Clinical Considerations 27 Retractors 27 Photographic Mirrors and Contrasters 27 Field of View 30 Cross‐infection Control 31 Health and Safety 32 Location 33 Supports 39 Delegation 40 Patient Consent 41 References 42 3 Technical Concepts and Settings 45 Every Picture Tells a Story 45 Setting the Tone 48 Lighting 48 Depth of Field 52 Exposure and Histogram 57 White Balance 63 Resolution 64 Other Settings 68 References 68 4 Composition and Standardisation 69 Composition 69 Dominance 69 Positioning 72 Leading the Eye 79 Balance 83 Standardisation 84 Standardisable Factors 89 Non‐standardisable Factors 92 References 94 Section 2 Photographic Set‐ups 97 5 Extra‐Oral and Intra‐Oral Images 99 Positioning 99 The Essential Dental Portfolio 101 Extra‐Oral (Dento‐Facial) Compositions 103 Intra‐Oral Compositions 107 Optional Compositions 117 References 135 6 Portraiture 137 Lighting for Portraiture 137 Manipulating Light 138 Colour Temperature 138 Direction: Key Light 140 Intensity and Size 147 Fill Light 150 Background Light 153 Clinical Portraiture Set‐Up 154 The Essential Portrait Portfolio 156 Optional Clinical Portraits 164 Non‐clinical Portraiture Set‐up 166 Generic Studio Portrait 167 Flattering Portrait 167 Profile Portrait 168 Coloured Gel Portrait 170 Classical Smile Line Portrait 171 Clinical vs. Non‐clinical Portraiture 173 References 173 7 Bench Images 175 Uses of Bench Images 175 Backgrounds and Supports 178 Lighting 183 Bench Image Set‐ups 184 Equipment Settings 186 Dental Casts (Models) with Black Background 189 Dental Cast with Coloured Background 190 Implant Supported Temporary Crown with Red Background 190 Perspex Backgrounds 193 Bokeh Composition 195 Stroboscopic Effect 196 References 202 8 Special Applications 203 Detailed Analysis of Hard and Soft Tissues 203 Opalescence and Fluorescence 208 Fibre‐Optic Illumination 215 UV Illumination 215 Colour Fidelity 216 Shade Analysis 221 Scale Reference Markers 227 Annotations 230 Bleaching (Tooth Whitening) 236 Phonetics 236 Occlusal Analysis 239 Treatment Sequences 242 Endodontic Documentation 246 Focus Stacking 247 Video 247 Promotional and Artistic Imagery 248 References 248 Section 3 Processing Images 251 9 Processing Images 253 Monitor Calibration 253 File Formats 254 Imaging Software 255 Image Processing 260 Colour Spaces 262 White Balance 265 Exposure 265 Orientation, Scaling and Cropping 273 Artefact Removal 285 Local Adjustments 286 Sharpening 287 References 293 10 Exporting, Managing and Using Images 295 Exporting Files 295 Output Location 295 Naming Conventions (Formats) 297 Export Recipes 299 Image Management 301 Using Images 306 Documentation 306 Communication 307 Marketing 313 Education 315 References 331 Index 333

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Book SynopsisA quick reference and revision guide on the most common oral and perioral diseases seen in clinical practice Clinical Guide to Oral Diseases is a concise reference on the common diseases encountered in daily practice. Presenting a large selection of clinical cases, this user-friendly resource covers a range of oral and perioral lesions located in hard and soft tissues of the mouth and neck, as well as oral manifestations of various systemic diseases. Nearly 300 high-quality color images complement succinct descriptions of clinical cases seen in both community and hospital care settings. Divided into three parts, the text first covers oral lesions classified by their color, appearance, and symptomatology such as bleeding, disturbances of saliva, taste, and orofacial pain. Part two describes the most common oral lesions by location, including those in the buccal mucosae, floor of mouth, gingivae and jaws, lips, neck, palate, salivary glands, tongue, and teeth. The third part encompassTrade Review"This book allows the reader to learn about oral medicine in a novel way. It uses simple clinical photographs to guide students, general practitioners and oral medicine experts toward the correct diagnosis. Several pathologies are introduced through brief descriptions, often accompanied by tables. The in-depth analysis is followed by multiple-choice questions along with their answers and explanations. The questions are organised into three difficulty levels that target students, general practitioners and oral medicine experts, respectively. Furthermore, oral pathologies are presented using three parameters: symptoms and clinical appearance, location and normal variations, to guide the reader through the diagnostic process."- Andrea Sardell, University of Milan, Italy. Published in Oral Diseases (May 23) "The book contains an astoundingly rich collection of clinical cases covering virtually every oral disease, 230 to be exact, each mapped to a detailed history and description of examination/laboratory findings, along with excellent clinical or radiographic images. The unique aspect of this book is the learning process for the reader because each case is mapped to three multiple choice questions which allows the reader to consider important facets of each case, such as identifying important features of the pathogenesis of a disease, formulating a differential diagnosis, or selecting an appropriate treatment ...This book has depth and academic rigour and I applaud the clinical expertise demonstrated throughout."—A. Ross Kerr DDS, MSD, Diplomate, American Board of Oral Medicine, Clinical Professor, New York University College of Dentistry, USA "Dr Malamos has advanced the publication ethos of Professor Scully in his creation of an excellent text book that demonstrates the breadth of 21st century Oral Medicine practice. The use of case studies that include questions with detailed answers, excellent images and helpful tables and figures the key aspects of the diagnosis and management of common, and many uncommon, disorders are extremely well described. This, together with the electronic format ensures that this book will not only inform readers but allow them to move seamlessly within and across different sections. I believe this textbook is an important to present and future practitioners of Oral Medicine."—Professor Stephen Porter, Institute Director, UCL Eastman Dental Institute, UK "Clinical Guide to Oral Diseases is an intelligently designed book with just over 400 pages of text supported by almost 300 high quality colour images. It utilizes a case-based learning approach to provide the reader with a comprehensive approach to the clinicalassessment scenario. The text contains relevant contemporary material, which provides the student or interested clinician with the necessary variety of clinical scenarios to contextualize their knowledge and most importantly, support the transfer of this approachinto the clinical arena. The material will be of use to a wide variety of clinicians involved in the delivery of clinical dentistry, from students (both undergraduate and postgraduate), to trainees at MFDS level and then forthose looking to gain specialist qualifications. It would even provide a very appealing format for general medical practitioners and other non-oral based clinicians. Clinical Guide to Oral Diseases is to be recommended because the depth and clarity of detail provided reminds us all of the legacy left by one of the authors, Crispian Scully, who despite his passing leaves behind a body of knowledge few are ever likely to match."—Professor StJohn Crean, Pro Vice Chancellor, University of Central Lancashire, PrestonTable of ContentsPreface vii Foreword ix Acknowledgment xi About the Companion Website xiii Section I 1 1 Bleeding 3 2 Blue and/or Black Lesions 19 3 Brown Lesions 35 4 Malador 51 5 Muscle Deficits (Trismus/Paralysis) 67 6 Orofacial Pain 83 7 Red Lesions 99 8 Saliva Disturbances (Xerostomia/Sialorrhea) 115 9 Swellings (Diffuse/Lumps) 131 10 Taste Deficits 147 11 Ulcerations 163 12 Vesiculobullous Lesions 179 13 White Lesions 195 14 Yellow Lesions 209 Section II 223 15 Buccal Mucosa 225 16 Floor of the Mouth 233 17 Gingivae 241 18 Jaws 251 19 Lips 261 20 Neck 271 21 Palate 279 22 Salivary Glands (Minor/Major) 287 23 Teeth 297 24 Tongue 321 Section III 331 25 Normal Variations 333 26 Oral Lesions According to Patient’s Age 349 27 Clinical Tests, Signs and Phenomena 369 Abbreviations 387 Diagnostic Flow Charts According to the Location of Oral Lesions 389 Appendix: ICD-10 Codes of Oral Diseases/Lesions 407 Index 413

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Book SynopsisMolecularly imprinted polymers (MIPs) are an important functional material because of their potential implications in diverse research fields. The materials have been developed for a range of uses including separation, environmental, biomedical and sensor applications.Table of ContentsPreface xiii Part 1 Strategies of Affinity Materials 1 Recent Molecularly Imprinted Polymer-based Methods for Sample Preparation 3 Antonio Martín-Esteban 1.1 Introduction 3 1.2 Molecularly Imprinted Solid-phase Extraction 6 1.3 Molecularly Imprinted Solid-phase Microextraction 14 1.4 Molecularly Imprinted Stir Bar Sorptive Extraction 17 1.5 Other Formats 18 1.6 Conclusions 20 References 21 2 A Genuine Combination of Solvent-free Sample Preparation Technique and Molecularly Imprinted Nanomaterials 29 Santanu Patra, Ekta Roy, Rashmi Madhuri and Prashant K. Sharma 2.1 Introduction 30 2.2 Molecularly Imprinted Polymer Modified Fiber for Solid-phase Microextraction 40 2.3 In-tube Solid-phase Microextraction Technique 55 2.4 Monolithic Fiber 58 2.5 Micro-solid-phase Extraction 70 2.6 Stir-bar Sorptive Extraction 73 2.7 Conclusion and Future Scope 76 Acknowledgments 76 Abbreviations 77 References 78 3 Fluorescent Molecularly Imprinted Polymers 89 Kornelia Gawlitza, Wei Wan, Sabine Wagner and Knut Rurack 3.1 Introduction 89 3.2 Classes of Emitters to Endow MIPs with Fluorescence 91 3.3 Fluorescent Molecularly Imprinted Silica 108 3.4 Post-imprinting of MIPs 111 3.5 fMIPs as Labels 113 3.6 Formats for fMIPs 115 3.7 Conclusion 119 References 120 4 Molecularly Imprinted Polymer-based Micro- and Nanotraps for Solid-phase Extraction 129 Rıdvan Say, Rüstem Keçili and Arzu Ersöz 4.1 Introduction 130 4.2 MIPs as SPE Materials 130 4.3 Conclusions 149 References 153 5 Imprinted Carbonaceous Nanomaterials: A Tiny Looking Big Thing in the Field of Selective and Secific Analysis 165 Ekta Roy, Santanu Patra, Rashmi Madhuri and Prashant K. Sharma 5.1 Introduction 166 5.2 Graphene-modified Imprinted Polymer 179 5.3 Carbon Nanotubes-modified Imprinted Polymer 190 5.4 Combination of graphene, CNTs, and MIPs 197 5.5 Graphene Quantum Dots and/or Carbon Dots 198 5.6 Fullerene 201 5.7 Activated carbon 202 5.8 Conclusions 203 Acknowledgments 204 List of abbreviations 204 References 205 6 Molecularly Imprinted Materials for Fiber-optic Sensor Platforms 217 Yavuz Orhan Yaman, Necdet Başaran, Kübra Karayagiz, Zafer Vatansever, Cengiz Yegin, Önder Haluk Tekbaş and Müfrettin Murat Sari 6.1 Introduction 218 6.2 Material Aspect: Morphology and Physical Forms of MIPs in FO Sensors 223 6.3 Molecularly Imprinting Technology for Fiber-optic Sensors 231 6.4 State-of-the-art Fiber-optic Sensors Applications Using Molecularly Imprinted Materials 268 6.5 Conclusion 273 References 274 Part 2 Rational Design of MIP for Advanced Applications 7 Molecularly Imprinted Polymer-based Sensors for Biomedical and Environmental Applications 285 Anca Florea, Oana Hosu, Bianca Ciui and Cecilia Cristea 7.1 Introduction 285 7.2 Molecularly Imprinted Polymers for Analytes of Biomedical Interest 296 7.3 Molecularly Imprinted Polymers for Analytes of Environmental Interest 306 7.4 Conclusion 314 Acknowledgments 316 References 316 8 Molecularly Imprinted Polymers: The Affinity Adsorbents for Environmental Biotechnology 327 Bo Mattiasson and Gizem Ertürk 8.1 Introduction 327 8.2 Molecularly Imprinted Polymers 329 8.3 Monomers 329 8.4 Cross-linking Agents 331 8.5 Mode of Polymerization 332 8.6 Cryogels 334 8.7 Process Technology 336 8.8 Applications 338 References 345 9 Molecular Imprinting Technology for Sensing and Separation in Food Safety 353 Baran Önal Ulusoy, Mehmet Odabaşi and Neşe Hayat Aksoy 9.1 Food Safety 354 9.2 Food Analysis 355 9.3 Current Separation Methods Used for Food Safety Purposes 356 9.4 What Is MIP? 357 9.5 MIP Applications Used for Food Safety Purposes 359 References 377 10 Advanced Imprinted Materials for Virus Monitoring 389 Zeynep Altintas 10.1 Introduction 390 10.2 Virus Imprinting 393 10.3 Artificial MIP Receptors for Viruses 398 10.4 Virus Monitoring and Detection Using Biomimetic Sensors 399 10.5 Virus Imprinting for Separation Technologies 401 10.6 Conclusions 405 References 406 11 Design and Evaluation of Molecularly Imprinted Polymers as Drug Delivery Systems 413 André Luís Morais Ruela and Gislaine Ribeiro Pereira 11.1 Introduction 414 11.2 Synthesis and Characterization of MIPs Intended for Drug Release Using Non-covalent Approaches 418 11.3 Design and Evaluation of Drug Delivery Systems Based on MIPs 436 11.4 Conclusions 445 References 446 12 Molecularly Imprinted Materials for Controlled Release Systems 455 Yagmur Yegin, Gökhan Yilmaz, Ömer Karakoç, Cengiz Yegin, Servet Çete, Mustafa Akbulut and Müfrettin Murat Sari 12.1 Introduction 456 12.2 Selectivity, Release Mechanism and Functionality of MIPs-based CR Systems 459 12.3 Molecularly Imprinted Polymers Production for Controlled Release 482 12.4 Controlled Release Applications Using Molecularly Imprinted Materials-based Controlled Release 491 12.5 Conclusion 506 References 507 13 Molecular Imprinting: The Creation of Biorecognition Imprints on the Biosensor Surfaces 523 Gizem Ertürk and Bo Mattiasson 13.1 Introduction 523 13.2 Molecular Imprinting 524 13.3 Microcontact Imprinting 525 13.4 Capacitive Biosensors 529 13.5 Surface Plasmon Resonance Biosensors 541 13.6 Concluding Remarks 549 References 550 14 Molecular Imprinted Polymers for Sensing of Volatile Organic Compounds in Human Body Odor 561 Sunil Kr. Jha 14.1 Introduction 562 14.2 MIP-QCM Sensor Array Preparation 573 14.3 Chemical Vapor Sensing 576 14.4 Analysis Outcomes 603 14.5 Conclusion 624 Acknowledgments 624 References 624 15 Development of Molecularly Imprinted Polymer-based Microcantilever Sensor System 637 Meltem Okan and Memed Duman 15.1 Introduction to Mass Sensors 637 15.2 Principles of Mass Sensors 640 15.4 Molecularly Imprinted Polymer Technology 655 15.5 Molecularly Imprinted Polymer-based QCM Sensors 658 15.6 Ongoing Studies on Molecularly Imprinted Polymers-based Microcantilevers 661 Acknowledgments 669 References 669

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Book SynopsisCysts of the Oral and Maxillofacial Regions The new Fifth Edition of Shear's Cysts of the Oral and Maxillofacial Regions delivers a comprehensive treatise on cysts that arise in the oral and maxillofacial tissues. It is the gold-standard on oral and maxillofacial cysts for professionals working in head and neck pathology, oral medicine, head and neck surgery, and radiology. The book has been completely revised and rewritten to enable readers to easily access key facts and important information that will assist in diagnosis and management of these lesions. The text has been updated, with increased emphasis on histopathology and differential diagnosis, and with a new layout that makes information more accessible to students and trainees at all levels, as well as to non-specialist clinicians and general pathologists faced with an individual lesion that requires diagnosis and management. Key features include: A new chapter that reviews the pathogenesis of cystsTrade Review"All information is presented in a clear and accessible manner for everyone involved in oral medicine and pathology, from a dental student to a general practitioner, maxillofacial surgeon, head and neck surgeon, general pathologist, or specialist. in pathology and oral medicine. The information is presented in a very accessible and easy to consult manner, the book contains very clear diagrams and tables that simplify the understanding of the information, and the use presence in each chapter of boxes that summarize and highlight the most relevant information is a very useful feature."- Ronell Bologna-Molina, Faculty of Dentistry, Universidad de la República, Uruguay. Published in Oral Diseases (May 2023)"The chapters have been reorganised to present the most common lesions first, making the text easier to read and providing a thorough explanation of the clinical and radiographic features, pathogenesis, histopathology, and treatment of each cyst. An additional chapter has been added on the pathogenesis of cysts, which provides an overview of the phases of cyst formation and the interface between cysts and tumours. Variants are discussed only where they may affect diagnosis and management...Overall, the fifth edition updates bring welcome changes which make it more appealing and relevant to all levels of student, trainees, and specialists."- Glesni Hitches, Published in British Dental Journal (April 2023)Table of ContentsPreface to the Fifth Edition viii Foreword x Acknowledgements xi 1 Classification and Frequency of Cysts of the Oral and Maxillofacial Regions 1 2 General Considerations 6 3 Radicular Cyst 20 4 Inflammatory Collateral Cysts 47 5 Dentigerous Cyst 62 6 Eruption Cyst 83 7 Odontogenic Keratocyst 87 8 Lateral Periodontal Cyst and Botryoid Odontogenic Cyst 140 9 Gingival Cysts 155 10 Glandular Odontogenic Cyst 164 11 Calcifying Odontogenic Cyst 182 12 Orthokeratinised Odontogenic Cyst 201 13 Nasopalatine Duct Cyst 214 14 Nasolabial Cyst 230 15 Cysts of the Salivary and Minor Mucous Glands 237 16 Surgical Ciliated Cyst 262 17 Pseudocysts of the Jaws: Simple Bone Cyst and Stafne Bone Cavity 270 18 Developmental Cysts 288 Bibliography 309 Index 357

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Book SynopsisA quick reference diagnostic guide for students and clinicians, covering a wide range of oral and dental developmental anomalies in children and adolescents Written by world-renowned pediatric dentists, this easily accessible, well-illustrated reference covers a wide range of oral and dental developmental anomalies in children and adolescents, and includes rare as well as more common conditions. Divided into two parts, the first part is dedicated to normal tissue initiation, formation, and development in the orodental region. The second part offers comprehensive pictorial descriptions of each condition and discussions of the treatment options available. A useful, quick reference atlas helping students and clinicians diagnose a wide range of oral and dental developmental anomalies in children and adolescentsHighly illustrated with clinical photographsDescribes both common and rare conditions, and explores treatment options Atlas of Pediatric Oral and Dental Developmental AnomalieTable of ContentsPreface xi About the Companion Website xiii 1 Oral and Dental Anatomy 1 1.1 The Lips: Macro Anatomy 1 1.2 The Palate 1 1.3 The Tongue 3 1.4 The Cheek and Floor of the Mouth 4 1.5 The Periodontium 5 1.6 The Periodontal Ligament (PL) 5 1.7 The Alveolar Bone 6 1.8 The Teeth: Dental Anatomy 7 1.9 Normal Occlusion 9 1.10 Classification of the Occlusion 10 2 Histology and Embryology of the Teeth and Periodontium 13 2.1 Tooth Histology 13 2.1.1 Enamel 13 2.1.1.1 Striae of Retzius 13 2.1.1.2 Hunter‐Schreger Bands 13 2.1.1.3 Gnarled Enamel (Spiral Enamel) 13 2.1.1.4 Enamel Tufts and Lamella 13 2.1.1.5 Enamel Surface 13 2.1.2 Dentine 14 2.1.2.1 Dentinal Tubules 14 2.1.2.2 Intratubular Dentine 15 2.1.2.3 Intertubular Dentine 15 2.1.2.4 Interglobular Dentine 15 2.1.2.5 Incremental Lines 15 2.1.2.6 Granular Layer of Tomes 15 2.1.3 Cementum 15 2.1.3.1 Cementum Connective Tissue 15 2.1.3.2 Fibrous Matrix 15 2.1.4 Dental Pulp 16 2.1.5 Periodontium 16 2.2 Embryology of Teeth: Life Cycle of the Tooth 16 2.2.1 Initiation (Bud) Stage 16 2.2.2 Proliferation (Cap) Stage 16 2.2.3 Histodifferentiation and Morphodifferentiation (Bell) Stage 16 2.2.4 Apposition and Calcification 16 3 Epidemiology and Diagnosis of Teeth Developmental Disturbances 17 3.1 Prevalence and Incidence 17 3.2 Diagnosis and Classification of Defects in Teeth 17 3.2.1 Cause of Disturbance 17 3.2.2 Extent of Involvement of the Dentition 18 3.2.3 The Structure Involved 18 3.2.3.1 Enamel Defects 18 3.2.3.2 Dentine Defects 18 3.2.3.3 Cementum Defects 18 3.2.3.4 Entire Tooth Structures Involved 18 3.2.4 Teeth Morphology 19 3.2.5 Teeth Size 19 3.2.6 Teeth Count 19 3.2.6.1 Hypodontia 19 3.2.6.2 Hyperdontia 19 3.2.7 Color of the Teeth 20 4 Etiology and Pathology of Teeth Disturbances 21 4.1 Genetically Originated Defects 21 4.1.1 Disturbances in Teeth Count 21 4.1.1.1 Reduced Numbers; Missing Teeth 21 4.1.1.2 Increase in Numbers; Extra Teeth 24 4.1.2 Disturbances in Proportion and Size of the Teeth 30 4.1.2.1 Large Size – Macrodontia 30 4.1.2.2 Small Size – Microdontia 30 4.1.2.3 Short Roots 32 4.1.3 Disturbances of Teeth Morphology 32 4.1.3.1 Dens Invaginatus 32 4.1.3.2 Dens Evaginatus (Talon Cusp) 33 4.1.3.3 Peg‐shaped Laterals 34 4.1.3.4 Fusion 34 4.1.3.5 Gemination 36 4.1.3.6 Dilaceration 38 4.1.3.7 Concrescence 39 4.1.3.8 Taurodontism 39 4.1.3.9 Hutchinson Incisors and Mulberry Molars 40 4.1.3.10 Odontomes 40 4.1.4 Defects of Teeth Structures 40 4.1.4.1 Enamel Defects 40 4.1.4.2 Dentine Defects 45 4.1.4.3 Cementum Defects 45 4.1.4.4 Enamel Dentin Cementum Defects 49 4.2 Congenital Diseases (in Utero) 50 4.2.1 Erythroblastosis Fetalis 50 4.2.2 Measles 51 4.2.3 Rubella 51 4.2.4 Pneumonia 52 4.2.5 Porphyria 52 4.2.6 Syphilis 52 4.2.7 Dehydration and Liquid Imbalance 52 4.3 Acquired (Environmental) Defects 53 4.3.1 Food and Diet 53 4.3.2 Vitamins and Minerals 53 4.3.3 Ions 55 4.3.4 Diseases and Drugs 56 4.3.4.1 Infantile Jaundice 56 4.3.4.2 Liver Disease, Liver Transplant 56 4.3.4.3 Cystic Fibrosis and Antibiotic Therapy 57 4.3.4.4 Lead Poisoning 59 4.3.4.5 Iron Intake 59 4.3.5 Primary Teeth Trauma and Tooth Infection 59 4.3.6 Short Roots 61 5 Eruption Disturbances of Teeth – Etiology and Diagnosis 63 5.1 Definition 63 5.2 Delayed Eruption 63 5.3 Early Eruption 63 5.4 Failed Exfoliation (Primary Dentition) 63 5.5 Early Exfoliation/Loss of Primary Teeth 65 5.5.1 Localized Factors 65 5.5.2 Systemic Factors 65 5.6 Failed Eruption and Impaction 66 5.7 Eruption Cysts 67 5.8 Ectopic Eruption and Transposition 69 5.9 Labial Frenulum and Lingual Frenulum 70 5.10 Under ‐eruption – Infraocclusion 70 5.11 Over ‐eruption 71 5.12 Palatal and Labial Cleft and Teeth Eruption 74 5.13 Malocclusion 76 5.13.1 Class I Malocclusion 76 5.13.2 Class II Malocclusion 76 5.13.3 Class III Malocclusion 77 5.13.4 General Spacing and Diastema Formation 78 5.14 Gingival Overgrowth 80 6 Self‐evaluation Section 81 Bibliography 109 Self‐evaluation Answer 115 Index 119

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Book SynopsisThe field of Dermatology is expanding at a rapid pace new research findings and advanced treatment technologies have amplified the need for concise and up-to-date information on this dynamic area of medicine. Dermatology at a Glance provides medical students and trainees with a clear introduction to dermatological practice. This valuable resource covers essential components of dermatology, from patient consultation and basic procedures to advanced treatments of skin disorders. Illustrated with over 300 high-quality slides and full-colour photographs, this book is an ideal reference for those seeking to interview and examine patients, identify and diagnose skin diseases, and develop treatment plans. Now in its second edition, Dermatology at a Glance offers revised coverage of the epidemiology, pathogenesis, and presentations of various skin disorders, and examines central aspects of the British Association of Dermatologists core curriculum. New chapters on topicTrade Review"It would be helpful to have on the shelf of your nurse's office or in your personal collection. If you are new to dermatology and on your journey to becoming a specialist nurse, I would very much recommend this book. For those of you like me who have worked for many years in this exciting field you will be sure to find new information on the less familiar topics you come across in your clinical setting. This book lays the foundations to equip nurses to move closer towards the status of 'specialist nurse'." (Dermatological Nursing, Vol 18. No 4) "Dermatology at a Glance covers a complex scientific subject in an easily understandable way. It is clearly and concisely written with key points highlighted at the end of each chapter, including a valuable additional warning section indicating possible pitfalls to be aware of or avoid. There is a helpful list of reliable information sources for further study, and the history and examination sections provide practical advice." (Clinical and Experimental Dermatology)Table of ContentsPreface to the Second Edition vii Preface to the First Edition viii About the Authors ix Foreword x Acknowledgements xi List of Abbreviations xii About the Companion Website xiv Part 1 Principles of Dermatology 1 1 Evidence-Based Dermatology 2 2 Dermatology: The Best on the Web 4 3 Dermatology: Then and Now 6 4 How the Skin Works 8 5 The Burden of Skin Disease 10 Part 2 The Patient Consultation 13 6 Taking the History 14 7 How to Examine the Skin 16 8 Diagnostic Clues 18 Part 3 Basic Procedures 21 9 Surgical Basics 22 10 Key Procedures 24 11 Dermoscopy 26 Part 4 Treatments 31 12 Topical Therapy 32 13 Practical Special Management 36 14 Systemic Therapies 38 Part 5 Inflammatory Diseases 43 15 Psoriasis 44 16 Atopic Dermatitis 47 17 Acne and Teenage Skin 50 18 Hidradenitis Suppurativa 52 19 Common Inflammatory Diseases 54 Part 6 ER Dermatology 57 20 Acute Dermatology 58 21 Blistering Skin Diseases 60 22 Drug Reactions 64 Part 7 Skin Infections 67 23 Bacterial Infections 68 24 Viral Infections 70 25 Fungal Infections 72 26 Skin Infestations 74 27 Tropical Skin Diseases 76 Part 8 Specific Sites 79 28 The Red Face 80 29 Oral and Genital Disease 84 30 Nail and Hair Disease 86 Part 9 Specific Ages 89 31 The Newborn Infant 90 32 The Child with a Rash 92 33 Skin Problems in Pregnancy 94 34 Elderly Skin 96 Part 10 Skin Allergy 99 35 Cutaneous Allergy 100 36 The Working Hands 102 37 Urticaria 104 Part 11 Skin Tumours 107 38 Benign Skin Lesions 108 39 Non-Melanoma Skin Cancers 111 40 Malignant Melanoma 114 41 Other Malignant Skin Conditions 116 Part 12 Photodermatology 119 42 Pigmentation 120 43 Sun and Skin 122 44 Phototherapy 124 45 Photodermatoses 126 Part 13 Systemic Diseases 129 46 Skin Signs of Systemic Disease 130 47 Autoimmune Disease and Vasculitis 133 48 The Immunosuppressed Patient 136 Part 14 Miscellaneous Conditions 139 49 Psychodermatology 140 50 Pruritus 142 51 Cosmetic Dermatology 144 52 Skin Breakdown 147 53 Hereditary Skin Diseases 150 Self-Assessment Clinical Picture Quiz 154 Clinical Picture Quiz Answers 162 References 166 Index 167

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Book SynopsisPractical Procedures in IMPLANT DENTISTRY Master the fundamentals and intricacies of implant dentistry with this comprehensive and practical new resource Practical Procedures in Implant Dentistry delivers a comprehensive collection of information demonstrating the science and clinical techniques in implant dentistry. Written in a practical and accessible style that outlines the principles and procedures of each technique, the book offers clinical tips and references to build a comprehensive foundation of knowledge in implantology. Written by an international team of contributors with extensive clinical and academic expertise, Practical Procedures in Implant Dentistry covers core topics such as: Rationale and assessment for implant placement and restoration, including the diagnostic records and surgical considerations required for optimal planning and risk management Incision design considerations and flap management, with an essential knowledge of regional neuro-vascular structures Table of ContentsForeword List of Contributors About the Companion Website 1. IntroductionChristopher C.K. Ho 2. Patient Assessment and History TakingChristopher C.K. Ho 3. Diagnostic RecordsAodhan Docherty and Christopher C.K. Ho 4. Medico-Legal Considerations and Risk ManagementChristopher C.K. Ho 5. Considerations for Implant Placement: Effects of Tooth LossKyle D. Hogg 6. Anatomic and Biological Principles for Implant PlacementKyle D. Hogg 7. Maxillary Anatomical StructuresKyle D. Hogg 8. Mandibular Anatomical StructuresKyle D. Hogg 9. Extraction Ridge ManagementTino Mercado 10. Implant Materials, Designs, and SurfacesJonathan Du Toit 11. Timing of Implant PlacementChristopher C.K. Ho 12. Implant Site PreparationTom Giblin 13. Loading Protocols in ImplantologyChristopher C.K. Ho 14. Surgical InstrumentationChristopher C.K. Ho 15. Flap Design and Management for Implant PlacementChristopher C.K. Ho, David Attia, and Jess Liu 16. Suturing TechniquesChristopher C.K. Ho, David Attia, and Jess Liu 17. Pre-surgical Tissue Evaluation and Considerations in Aesthetic Implant DentistrySherif Said 18. Surgical Protocols for Implant PlacementChristopher C.K. Ho 19. Optimising the Peri-implant Emergence ProfileDavid Attia 20. Soft Tissue AugmentationMichel Azer 21. Bone Augmentation ProceduresMichel Azer 22. Impression Taking in Implant DentistryChristopher C.K. Ho 23. Implant Treatment in the Aesthetic ZoneChristopher C.K. Ho 24. The Use of Provisionalisation in ImplantologyChristopher C.K. Ho 25. Abutment SelectionChristopher C.K. Ho 26. Screw versus Cemented Implant-Supported RestorationsChristopher C.K. Ho 27. A Laboratory Perspective on Implant DentistryLachlan Thompson 28. Implant BiomechanicsTom Giblin 29. Delivering the Definitive ProsthesisAodhan Docherty and Christopher C.K. Ho 30. Occlusion and ImplantsChristopher C.K. Ho and Subir Banerji 31. Dental Implant Screw MechanicsChristopher C.K. Ho and Louis Kei 32. Prosthodontic Rehabilitation for the Fully Edentulous PatientChristopher C.K. Ho 33. Implant MaintenanceKyle D. Hogg and Christopher C.K. Ho 34. The Digital Workflow in Implant DentistryAndrew Chio and Anthony Mak 35. Biological ComplicationsChristopher C.K. Ho 36. Implant Prosthetic ComplicationsChristopher C.K. Ho and Matthew K. Youssef Index

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