Industrial chemistry and chemical engineering Books
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Downstream Processing Biosurfactants Carotenoids
Table of ContentsGas phase biosensors.- Chromatography in the downstream processing of biotechnological products.- Extractive bioconversion of lactic acid.- Production of rhamnolipid biosurfactants.- Microbial carotenoids.
£42.74
Springer Fachmedien Wiesbaden Kreiselpumpen: Handbuch für Entwicklung,
Book SynopsisDie Wissenschaft der Kreiselpumpen in einem BuchDie komplexen Funktionen der Kreiselpumpe regen immer wieder neue Forschungsprojekte an. Dementsprechend müssen auch erfahrene Ingenieure ihr Wissen über Pumpen ständig überprüfen und erweitern. Dieses Buch fasst die bisherigen Forschungsergebnisse zum Thema Kreiselpumpen zusammen und verschafft Lesern einen Überblick zum derzeitigen Stand der Technik. Dabei liegt der Fokus auf hydraulischen Problemen, die es beim Bau von Pumpenanlagen zu überwinden gilt. Pumpensysteme in Theorie und PraxisDie aktuelle Ausgabe bezieht viele Erkenntnisse zur Strömungslehre mit ein, die Wissenschaftler in den letzten Jahren gewonnen haben. Das Handbuch zielt jedoch nicht allein darauf ab, theoretische Grundlagen zu vermitteln. Vielmehr zeigt es mithilfe von anschaulichen Beispielen, wie die Grundlagen der Hydraulik praktisch angewandt werden. Davon profitieren vor allem Fachkräfte in folgenden Bereichen:• Pumpenbau• Anlagenplanung• PumpenbetriebNur wenn Ingenieure physikalische Abläufe richtig erfassen, können sie daraus Lösungsansätze für konkrete Problemstellungen entwickeln. Zu diesem Zweck finden Leser auf 160 Tafeln und Tabellen alle wichtigen Fakten und Zusammenhänge. Hydraulische Kräfte verstehen und anwendenFür die fünfte Ausgabe hat der Autor Johann F. Gülich sein Buch über Kreispumpen umfassend überarbeitet. Zu den thematischen Ergänzungen zählen:• Schwingungen an Vertikalpumpen• Messungen zu hydraulischen Erreger- und Laufrad-Reaktionskräften• Wechselspannungen und Ermüdungsbrüche von Laufrädern• eine kontroverse Untersuchung zur Genauigkeit der Berechnungen von 3D-Strömungsvorgängen• Auslegung von Einlaufgehäusen und Doppelspiralen für mehrstufige PumpenTable of ContentsVorwort.- Formelzeichen.- Inhaltsverzeichnis.- Allgemeine strömungstechnische Grundlagen.- Bauarten und Leistungsdaten.- Grundlagen der hydraulischen Berechnung.- Kennlinien.- Teillastverhalten. 3-dimensionale Strömungsvorgänge und ihre Wirkung auf die Kennlinien.- Saugverhalten und Kavitation.- Berechnung und Entwurf der hydraulischen Komponenten.- Numerische Strömungsberechnungen.- Hydraulische Kräfte.- Schwingungen und Geräusche.- Verhalten der Kreiselpumpen in Anlagen.- Turbinenbetrieb. Allgemeines Kennfeld.- Einfluss des Fördermediums.- Werkstoffwahl für hohe Geschwindigkeiten.- Zur Auswahl und Qualität von Kreiselpumpen.- Allgemeine Daten und Formeln.- Sachverzeichnis.
£113.99
Harwood-Academic Publishers Polymer Yearbook 13
Book SynopsisPolymer Yearbook 13 brings together reviews and information on the progress of polymer science worldwide, including useful and topical information such as a list of new publications in polymer science and a compilation of dissertation abstracts. This volume includes reviews of key aspects of polymer science, including contributions from Russia, and details of important publications., This volume also contains reviews on state-of-the-art Japanese research presented at the annual Spring and Fall meetings of the Japanese Polymer Science Society. The aim of this section is to make information on the progress of Japanese polymer science, and on topics of current interest to polymer scientists in Japan, more easily available worldwide.Table of ContentsPreface, Contributors, REVIEW SECTION, Gennadi Efremovich Zaikov. 60th Birthday, 40 Years of Scientific Activity PVC Degradation in Blends with Other Polymers, Mathematical Modelling of the Mechanism of Some Aromatic Amine Inhibitors, Significance and Application of the Dynamic Rheological Method in Kinetorheology. Part II. High-Conversion Radical Polymerization of Some Water-Soluble Ionogen Monomers and the Gel Effect, Compression Moulding of Thermoplastic Elastomer Composites, New Metal Chelates as Antioxidant Stabilizers for Polymers and Low Molecular-Weight Substances, Spin Probes and Labels. A Quarter of a Century of Application to Polymer Studies, Spatial Organization of Polymer-Metal Coils in Liquid Solutions, Kinetics and Mechanism of the Inhibited Polymerization of Vinyl Monomers, Main Factors Influencing Flame Spread Velocity over Polymer Surfaces, Temperature Effects on Thermodestructive Processes, REVIEWS OF CONFERENCES, Reviews of Conferences in Russia, PROGRESS IN POLYMER SCIENCE IN JAPAN, Preface, Ionic Polymerizations, Polymer Dynamics and Rheology, Polymer Engineering and Technology, Photosensitive Polymers, Degradable Polymers, Hybrid Polymer Materials for Medical Use, Biopolymers, Physical Properties of Polymeric Solids, CURRENT AWARENESS, Dissertation Abstracts, Index
£546.25
Verlag Unser Wissen Landwirtschaftliche Rückstände
£22.50
Brill Photodegradation and Light Stabilization of
Book SynopsisPhotodegradation and light stabilization are very important aspects of polymer aging. Polymer degradation includes different types of processes: thermodegradation, oxidation, acting of ozone, photodegradation, radiation, hydrolysis, mechanical degradation, and biodegradation. It is very important to know the mechanism of polymer degradation in order to select stabilizers against the degradation. This volume presents the analysis of achievements in the field of photodegradation of polymers. It includes, first of all, data of Russian investigators who have decisively contributed in the development of this field of knowledge (the schools headed by academicians V.V. Korshak, N.M. Emanuel, N.S. Enikolopov, A.A. Berlin, and many others).Table of Contents1. Stabilization and Modification of Cellulose Diacetate 2. Stabilization and Modification of Polycaproamide 3. Stabilization and Modification of Polyethyl-Enerephthalate 4. Conclusion
£228.00
Brill Chemical Processes with Participation of
Book SynopsisThe book is devoted to kinetics and thermodynamics of the processes with participation of some biological compounds and their synthetic analogues. Aspects of their acting as model enzymes, molecular receptors, photo sensitizers, pharmocophores, and biopharmaceutical compounds are under consideration. Quantitative characteristics of transfer of cations, anions and small organic molecules, fermentative catalysis, diffusion of the drug molecular through biological membranes are found. Mechanisms of the processes are discussed. Biological activity of studied compounds is evaluated. Bio-damages of materials as well as adhesions of microorganisms on materials surface are investigated.Table of ContentsPreface, Foreword, Chapter 1: Synthetic and Natural Bacteriochlorins: Synthesis, Properties and Applications, Chapter 2: meso-Phenylporphyrins as Synthetic Models of Natural Porphyrins: Synthesis and Modification, Chapter 3: The Mechanism of Catalytic Action of the Coordination Centres of Catalase Synthetic Models, Chapter 4: Complexation of Porphyrins with Ions and Organic Molecules, Chapter 5: Chemical Activation of Porphyrins in Coordination Core Reactions, Chapter 6: Synthesis, Structure Peculiarities and Biological Properties of Macroheterocyclic Compounds, Chapter 7: The Photochemical Aspect of Reactions of Flavonols with Molecular Oxygen, Chapter 8: Solvation of Drugs as a Key for Understanding Partitioning and Passive Transport Exemplified by NSAIDs, Chapter 9: Biodamage of Materials: Adhesion of Microorganisms on the Surface of Materials, Chapter 10: Controlled Release of Aseptic Drug from Poly(3-hydroxybutyrate) Films: A Combination of Diffusion and Zero-order Kinetics, Chapter 11: Transport of Water as a Structurally Sensitive Process Characterizing the Morphology of Biodegradable Polymer Systems, Chapter 12: A Novel Technique for Measurement of Electrospun Nanofiber, Chapter 13: Image Analysis of Pore Size Distribution in Electrospun Nanofiber Webs: New Trends and Developments, Chapter 14: Electrospun Biodegradable and Biocompatible Natural Nanofibers: A Detailed Review
£199.50
Gordon and Breach Transport Processes in Plasmas with Strong
Book SynopsisThe first part of this monograph presents theoretical analysis of the thermophysical properties of strongly coupled coulomb systems. A new model is then developed, making it possible to calculate the full set of low temperature, multicomponent, nonideal plasma transport coefficients, based on the kinetic coefficients of strongly coupled coulomb systems and experimental data for the transport coefficients of Dense, Low temperature plasmas. This model can easily be implemented in the form of a set of computer algorithms, and the third part of the book shows how it can be used to solve important problems of high temperature gas dynamics, for example, heat and mass transfer in the shock layer of a space probe, stability of temperature and concentration fields in gas phase nuclear reactors, and critical phenomena in low temperature plasma dynamics.
£200.00
Taylor & Francis Ltd Recent Advances in Polymer Chemical Physics:
Book SynopsisThe Institute of Chemical Physics of the Russian Academy of Sciences has become one of the world's premiere centers for studies of polymeric materials; in use, during processing, and in harsh environments. The Institute's focus is on commercially available materials and their modifications to improve performance through advanced theoretical analysis and implementation of experimental results. Selected papers from the Institute have been incorporated into five sections-Stabilization and Degradation, Biochemistry , Photochemistry, Rheology and Flame Retardancy-and should provide invaluable background to producers of polymeric materials.Table of Contents1. Chemical Transformation of Polymers During Processing 2. Experimental Methods for Estimating Stabilizers; Efficiency 3. Quantitative Foundations of Polymer 4. Physico-Chemical Criteria for Estimating the Efficiency of Burn Dressings Biocompatibility and Biodestructibility 5. Photoradical Ageing of Polymers 6. A New Generation of Highly Efficient Fluorescent Polymers 7. Hydrodynamic and Conformational Parameters of the Macromolecules of Cellulose and Its Derivatives in Non-Aqueous Solutions 8. New Types of Ecologically Safe Flame Retardant Polymer Systems 9. Elastomeric Heat-Shielding Materials for Internal Surfaces of Missile Engines
£152.00
Taylor & Francis Ltd Clean Combustion Technologies: Proceedings of the
Book SynopsisThe seventy-five refereed papers in this volume represent the second in a series of biannual benchmarks for technologies that maximize energy conversion while minimizing undesirable emissions. Covering the entire range of industrial and transport combustion as well as strategies for energy R&D, these state-of-the-art contributions will be indispensable to mechanical and chemical engineers in academia and industry, and technical personnel in military, energy, and environmental agencies of government.Table of Contents1. Strategies 2. Pulverized Coal Combustion 3. Oil Combustion 4. Gas Combustion 5. Gas Fired Systems 6. Biomass Combustion 7. Fluidized Bed Combustion 8. Incinerators 9. Internal Combustion Engines 10. New Power Generation Cycles or Concepts 11. Control Technologies and Clean Technologies in Process Industries
£190.00
A A Balkema Publishers Polymer Concretes and Their Structural Uses:
Book SynopsisGeneral information & classification of polymer concretes; Characteristic features of the materials used; Theory of structure formation using polymer concretes & physical & chemical principles in formulating their compositions; Physical & mechanical properties of polymer concretes; Resistance of polymer concretes to aggressive media; Durability of polymer concrete structures; Effect of temperature & fire on polymer concrete structures; Design characteristics of polymer concrete & reinforced polymer concrete structures; Technology of producing polymer concrete products; Polymer sulphur concretes.
£152.00
CRC Press Immobilization on Polymers
Book SynopsisThis volume is devoted to the developments in the branch of polymer chemistry which deals with immobilized systems. These systems are widely used in fields connected with metabolism in humans, animals, plants and micro-organisms. The study of these artificial immobilized systems permits the understanding and design of the function and behaviour of natural substances in living organisms. The book contains the latest achievements in the field of synthesis of polymeric derivatives of different natural substances such as: proteins; peptides; amino acids; poly- and monosaccharides; nucleic acids; nucleosides; nucleotides; coenzymes; vitamines; alkaloids; antibiotics; steroids; hormones; and others. Special attention is given to natural and synthetic carriers and the influence of their chemical structure on the efficiency of systems obtained. This work should be of value and interest to researchers in the field of polymer chemistry, biotechnology and genetic engineering, medical chemistry, b
£199.50
CRC Press Polymer Surfaces and Interfaces Characterization
Book SynopsisPolymeric materials are used for a legion of applications in a wide array of technological areas, and their proper surface/interface characteristics are of cardinal importance for their applications. Therefore, the need to characterize polymer surfaces/interfaces and their suitable modification to impart desired characteristics is quite patent. This book chronicles the proceedings of the Symposium on Polymer Surfaces and Interfaces: Characterization, Modification and Application held as a part of the Society of Plastics Engineers Annual Technical Conference, Boston, May 7--11, 1995. The articles in this book address many aspects of polymer surfaces and interfaces. Topics covered include: various ways (chemical, photochemical, laser, flame, corona) to modify polymer surfaces; modification of contact lens surfaces; various ways to analyze/characterize polymer surfaces; metal/polymer interfaces; metal/polyimide adhesion; metal/self-assembled organic monolayer interfaces
£118.75
Brill Polymers Derived from Isobutylene. Synthesis,
Book SynopsisThis monograph aims to give an overview of recent chemical and technological developments in the area of polymers and co-polymers derived from isobutylene, which have a wide range of (industrial) applications. The scientific basis for presenting the material – application of the acid-base theory with a view to the fundamental steps of isobutylene polymerization – is combined with the application of quantum-chemical calculations of catalysts, linked active centers, separate elementary stages of the process, and critical analysis of some experimental data. In addition, a number of problems, such as the macrokinetic description of isobutylene polymerization, description of the balanced scheme of industrial production of isobutylene polymers, and initiation of isobutylene polymerization with the help of immobilized cationic catalysts are discussed. Special attention is given to ecological aspects of synthesis and application of isobutylene polymers. This book will be of value and interest to researchers in the areas of chemistry and physics of high-molecular compounds, as well as engineers and technologists specialized in the area of olefins and polyolefins.Table of ContentsPart 1 Scientific and technological aspects of isobutylene production: properties and production of isobutylene - physical properties, chemical properties, methods of isobutylene production, production of isobutylene in industry, special methods of isobutylene production, analysis of isobutylene; isobutylene polymerization - general ideas of polymerization, catalysts, polymerization mechanism, initiation, chain propagation, limiting of the chain propagation, problems of cationic polymerization of isobutylene, molecular engineering, features of fast polymerization processes, problems of kinetics of fast polymerization processes, kinetic features of isobutylene polymerization; macrokinetics of isobutylene polymerization -modelling of isobutylene polymerization as a fast chemical reaction, macroscopic features of isobutylene polymerization, novel fundamental regularities, on existence of several macroscopic regimes, on connection between geometrical size of the reaction zone and kinetic and hydrodynamic parameters, influence of linear flow motion rate on molecular-mass characteristics of resulting polymer, influence of the methods of catalyst transmission on molecular-mass characteristics of resulting polymer, heat regime of fast isobutylene polymerization, heat regime of polymerization in the absence of heat elimination, heat regime of polymerization with reaction mass boiling, efficiency of external heat elimination, optimization of molecular-mass characteristics of polymer in fast isobutylene polymerization, the zone model, estimation of molecular-mass polyisobutylene characteristics in the absence of heat elimination at the multistage catalyst delivery into the reacting turbulent zone. (Part contents).
£190.00
Brill Polyimides and Other High Temperature Polymers:
Book SynopsisThis volume documents the proceedings of the Second International Symposium on Polyimides and Other High Temperature Polymers: Synthesis, Characterization and Applications, held in Newark, New Jersey, December 3-6, 2001. Polyimides possess many desirable attributes, so this class of materials has found applications in many technologies ranging from microelectronics to high temperature adhesives to membranes.This volume contains a total of 32 papers, all rigorously peer reviewed and revised before inclusion, addressing many aspects and new developments in polyimides and other high temperature polymers. The book is divided into two parts: Synthesis, Properties and Bulk Characterization and Surface Modification, Interfacial or Adhesion Aspects and Applications. The topics covered include: synthesis and characterization of a variety of polyimides; photoalignable polyimides; high-modulus poly(p-phenylenepyromellitimide) films; structure-property relationships in polyimides; aromatic benzoxazole polymers; polybenzobisthiazoles; polyimide L-B films; transport of water in high Tg polymers; surface modification of polyimides; adhesion of metal films to polyimide and other polymers; investigation of interfacial interactions between metals and polymers; polyimide film surface properties; applications of polyimides in microelectronics, as membranes for gas separation, as composite films; fabrication of thin-film transistors on polyimide films; polyimide modified with fullerenes; semicrystalline polyimides for advanced composites; and wear performance of polyetherimide composite.Table of ContentsPart 1: Synthesis, Properties and Bulk Characterization 1. Poly(amic acid)s and their ionic salt solutions: Synthesis, characterization and stability study 2. A new interpretation of the kinetic model for the imidization reaction of PMDA-ODA and BPDA-PDA poly(amic acid)s 3. Synthesis and characterization of new organosoluble poly(ether imide)s derived from various novel bis(ether anhydride)s 4. Synthesis of novel polyimides from dianhydrides with flexible side chains 5. Polyimides based on rhenium(I) diimine complexes 6. New highly phenylated bis(phthalic) and bis(naphthalic) anhydrides and polyimides therefrom 7. New photoalignable polyimides and their ability to control liquid-crystal alignment 8. Proton conducting polyimides from novel sulfonated diamines 9. High-modulus poly(p-phenylenepyromellitimide) films obtained using a novel gel-drawing technique 10. Effect of structure on the thermal behaviour of bisitaconimide resins 11. l-Amino-4,5-8-naphthalenetricarboxylic acid-l,8-lactam-4,5-imide-containing macrocycles: Synthesis, molecular modeling and polymerization 12. Synthesis of aromatic benzoxazole polymers for high Tg, low dielectric properties 13. Polybenzobisthiazoles – Critical issues in their performance and properties 14. Electrical breakdown and electrostatic phenomena in ultra-thin polyimide Langmuir-Blodgett films 15. Humid ageing of polyetherimide: Chemical and physical interactions with water 16. Transport of water in high Tg polymers: A comparison between interacting and non-interacting systems Part 2: Surface Modification, Interfacial or Adhesion Aspects and Applications 17. New developments in the adhesion promotion of electroless Ni or Cu films to polyimide substrates 18. Surface modification of polyimide to improve its adhesion to deposited copper layer 19. Study on the structure and adhesion of copper thin films on chemically modified polyimide surfaces 20. Chemical interaction of Fe, Ni and Au with poly(vinyl chloride) and poly(tetrafluoroet
£218.50
Brill Modern Polymer Flame Retardancy
Book SynopsisThere are obvious benefits in using flame-retardants, as many human lives and property are saved from fire. A large number of compounds have been identified as being used as flame-retardants. At present, knowledge of long-term effects resulting from exposure to flame retardants and their breakdown products is limited. The aim of this volume in the book series New Concepts in Polymer Science is to provide a general overview of the nature, mechanism of action, use and environmental hazards for a number of flame-retardants. This monograph (together with the book by the same authors, Ecological Aspects of Polymer Flame Retardancy (1999) will valuable to anyone interested in the field of flame-retardant chemicals.Trade Review'For those looking for an introduction and update in regard to polymer flame retardancy, this book can be useful. [...] There are over 400 references and an excellent listing of flame retardants, suppliers and trade names. [...] It is also recommended as another useful resource for libraries or particular groups involved with polymer flame retardant approaches.' Eli M. Pearce (New York), Polymer News, 2004Table of ContentsChapter 1. General Concepts of Polymer Combustion Chapter 2. General Methods for the Estimation of Polymer Flammability Chapter 3. Polymer Flame Retardants Chapter 4. Polyhalogenated Flame Retardants and Dioxins Chapter 5. New Types of Ecologically Friendly Flame Retardants
£180.50
CRC Press Gels Genes Grafts and Giants
Book SynopsisIn celebration of Allan HoffmanÃââs 70th birthday, a symposium entitled Gels, Genes, Grafts and Giants was held in Maui in December 2002. This symposium, organized by The University of Washington Engineered Biomaterials (UWEB) NSF Engineering Research Center, was a great success, with many excellent papers presented by scientists from all over the world. All those who made oral or poster presentations at the symposium, but also those who worked with Allan Hoffman in the past or worked in similar research areas were invited to submit articles for special issues of the Journal of Biomaterials Science, Polymer Edition. The papers from these special issues of the journal have now been published in one hardcover book.
£204.25
Brill Stationary and Non-Stationary Kinetics of the
Book SynopsisThe main focus in this monograph is on models of the kinetics of photo-initiated polymerization of mono- and bi-functional monomers up to the high conversion stage, their derivation, analysis and comparison with the experimental data. This monograph can be useful for scientists, engineers, post-graduate training students and students who are interested in problems both of the polymerization kinetics and general chemical kinetics.Trade Review'The main focus of the monograph is on model of kinetics of photoinitiated polymerization of mono and bifunctional monomers up to high conversion state, their derivation, analysis and comparison with experimental data. Great attention is paid to the polymerization up to high conversion, which is considered as a chemical process in a system changing its own phase…useful for scientists, engineers, and postgraduate training students who are interested in problems both of the polymerization kinetics and general chemical kinetics. The book is aimed mainly at those looking for specialized knowledge in parts of kinetics of polymerization initiated by photons.' Pavol Hrdlovic, Polymer News, 2005.Table of ContentsAbbreviations and symbols, Preface, Introduction, Chapter 1. Methodological principles of chemical kinetics, Chapter 2. The method of routes and kinetic models, Chapter 3. Problems of stationary kinetics of polymerization up to the high conversion state, Chapter 4. Non-stationary (postpo1ymerization) polymerization kinetics problems, Chapter 6. Stationary kinetics of the linear polymerization up to the high conversion state, Chapter 7. Non-stationary kinetics (postpolymerization), Chapter 8. Statistics of self-avoiding random walks and the stretched exponential law, Appendix. A new method for surfaces gluing based on the effect of the postpolymerization, References, Subject index
£80.74
CRC Press Thermal Stability of Engineering Heterochain
Book SynopsisThis book presents investigation results of thermal transformations in thermoresistant polymers: polysulfones, polyester-imides, aliphatic-aromatic polyimides and polyamides, liquid-crystal aromatic co-polyesters, polyphenylquinoxalines at temperatures of materials and articles processing and operation. An important result of investigations is the determination of thermooxidative degradation regularities for aliphatic-aromatic heterochain polymers and description of the degradation mechanism. The applied aspect of this work is the approach to stabilization of thermoresistant polymers and composite materials derived from them using additives and analysis of the mechanism of high-temperature inhibited oxidation. The book presents results which have been obtained through many years of research until recently, mostly obtained by scientists of G.S. Petrov Research Institute of Polymeric Materials (Moscow, Russia) Ãâ✠one of the leading Institutes in this branch - which have
£266.00
Brill Transformations of Allyl-Substituted and
Book SynopsisThe book generally shows the interrelation between allyl unit structure of the initial ester and composition and structure of its products. The first part studies the pathways of chemical regrouping in chlorallylaryl and bisarylallyl esters using quantum-chemical calculations. Energy parameters, structural features and electron structure of intermediates and transition states are also discussed. Simple and regioselective methods for compound synthesis inaccessible in other production techniques are developed. For the first time, new four- and eight-term nitrogen-containing heterocyclic compounds were produced by aniline alkenylation technique. In 0.05% aqueous solution these compounds displayed 100% activity in suppression of sulfate-reducing bacterium growth. Two new classes of complex action preparations designed for the oil production rate increase were obtained by heterocyclic amine alkenylation. Production methods for N-alkenyl ammonium salts derived from hexamethylene tetramine are developed and introduced into production, and compounds are used on oil fields. In the second part production methods of new mono-, di-, tri- and tetra-tert-butyl hexamethylene tetramine chlorides are discussed. These compounds fully suppress sulfate-reducing bacterium growth already in 200 – 500 mg/l concentration. A universal technology deriving bactericides and sulfide corrosion inhibitors for metals from methallyl chloride is developed. It also gives a method for organochlorine waste and methallyl chloride production wastewater management, safe for the environment.Table of ContentsPreface, Part I: Synthesis and properties of alkenyl aryl esters and N-alkenyl substituted amines, Part II: Development of waste management technique for methallyl chloride production and synthesis of small-tonnage chemical products
£190.00
CRC Press Polyimides and Other High Temperature Polymers
Book SynopsisThis volume chronicles the proceedings of the Third International Symposium on Polyimides and Other High Temperature Polymers: Synthesis, Characterization, and Applications, held in Orlando, December 17-19, 2003. This volume is divided into three parts. Part 1. ÃâÅSynthesis, Properties and Bulk CharacterizationÃâ; Part 2 ÃâÅHybrids and CompositesÃâ and Part 3 ÃâÅApplications and General PapersÃâ. The topics covered include: Synthesis, characterization and processing (including some novel approaches) of a variety of polyimides and other high temperature polymers; structure-property relationships; hybrids and nanocomposites using these materials and their characterization, properties and applications; segmental dynamics in polyimide materials; photoalignable polyimides; photoconductivity and photosensitivity of polyimides; ultrafiltration membranes from polyetherimide; polyimide as a tunneling barrier; polymer materials for nonlinear optical applications; alignment of SWNTs in rig
£228.00
Pan Stanford Publishing Pte Ltd Novel Nanocomposite Coatings: Advances and
Book SynopsisNanocomposite materials as a special class of nanostructured materials have recently attracted great interest due to their extraordinary mechanical properties as well as thermal stability and oxidation resistance. The unique structure and exceptional properties make nanocomposite materials a possible alternative to traditional polycrystalline materials, which have met their limits in many recent engineering applications. In particular, nanocomposite coatings synthesized by plasma-assisted deposition processes under highly non-equilibrium conditions provide a high potential for new applications as protective and functional coatings in automotive, aerospace, tooling, electronic, or manufacturing industry.This book provides a comprehensive overview of the synthesis of Si-containing hard nanocomposite coatings based on transition metal nitrides by plasma-based thin film processing. It demonstrates the full versatility of these nanocomposites for low Si-containing coatings tailored with superior mechanical properties and novel high Si-containing nanocomposite coatings with extraordinary thermal stability and resistance against oxidation optimized for high-temperature applications. It pays special attention to understanding growth mechanisms of these structures under specific deposition conditions, structure–property relations, and stability of individual constituents to enhance their functionality for various applications.Table of ContentsSynthesis of New Nanostructured Materials. Nanocrystalline Materials. Multilayers and Superlattices. Nanocomposite Films. Thin Film Processing. Principles of Plasma Discharges. Physical Sputtering and Transport of Sputtered Material. Sputter Deposition Techniques. Reactive Sputter Deposition. Film Formation and Structure. Condensation of Sputtered Material. Interface Formation. Nucleation and Growth. Microstructure of Thin Films, Structure Zone Models, Advantages and Limitations of Sputter Deposition Processes. Structure-Property Relation in Hard Films. Me-Si-N Films With a Low and Intermediate Si Content. Structure, Morphology and Phase Composition Hardness and Macrostress Oxidation Resistance Problems with Reproducibility. Novel nanocomposite films - Zr-Si-N Films with a High Si Content. Deposition Rate. Elemental Composition. Chemical Bonding and Phase Composition. Electrical and Optical Properties. Structure. Morphology. Surface Roughness. Mechanical Properties. Macrostress. Effect of Substrate Bias. Thermal Stability. Oxidation Resistance. High Si-containing W-Si-N Nanocomposite Films. Deposition Rate. Elemental Composition. Chemical Bonding and Phase Composition. Structure. Morphology. Surface Roughness. Mechanical Properties. Macrostress. Oxidation Resistance. Characterization of Thin Films. Mechanical Properties. X-Ray Diffraction Analysis. Stress Measurement. Film Thickness Measurement. Scanning Electron Microscopy. Energy Dispersive X-Ray Spectrometry. Differential Scanning Calorimetry. Thermogravimetric Analysis.
£109.25
Pan Stanford Publishing Pte Ltd Amorphous Chalcogenides: Advances and
Book SynopsisThis book provides a comprehensive overview of the chalcogenide glass science and various applications based on the glasses. It starts with a review on the glass-forming ability of various systems, followed by a discussion on the structural and physical properties of various chalcolgenide glasses and their application in integrated optics. The chapters have been contributed by prominent experts from all over the world, and therefore, the book presents the recent research advances in the area. This book will appeal to anyone who is involved in glass science and technology and glass application.Table of ContentsGlass formation in several novel chalcogenide systems. Relaxation and Fragility in Chalcogenide Network Glasses. Photoinduced deformations in chalcogenide glasses. Structural and Physical Properties of GexAsySe1-x-y Glasses. Atomistic Modeling and Simulations of Chalcogenide Glasses. Broadband Near Infrared Photoluminescence of Doped Chalcogenide glasses. Thin Film and Fiber Structures for Chemical and Biological Sensing. Fabrication of Passive and Active Tellurite Thin Films and Waveguides for Integrated Optics.
£109.25
Pan Stanford Publishing Pte Ltd Computational Chemogenomics
Book SynopsisThis book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity analysis. Both ligand-based and structure-based in silico approaches, as reviewed in this book, play important roles for all these applications. Computational chemogenomics is expected to increase the quality and productivity of drug discovery and lead to the discovery of new medicines.Table of ContentsForeword. Chemogenomics Approaches for the Quantitative Comparison of Biological Targets. Considerations on the Drug-like Chemical Space. Chemogenomic Protein-Family Methods in Drug Discovery: Profile-QSAR and Kinase-Kernel. Virtual Screening and Target Fishing for Natural Products Using 3D Pharmacophores. Computational Analysis of Ligand Binding Pockets. Binding Site Similarity Search to Identify Novel Target-Ligand Complexes. ChemProt: A Disease Chemical Biology Database. Scientific Requirements for the Next Generation Semantic Web-based Chemogenomics and Systems Chemical Biology Molecular Information System OPS. Index.
£109.25
Pan Stanford Publishing Pte Ltd Bio-Inspired Wettability Surfaces: Developments
Book SynopsisThrough natural evolvement in thousands of years, biosurfaces have become highly adaptable to display their biological functions perfectly. Interestingly, they have developed micro-/nanostructures with gradient features to achieve smart wetting controls, such as ultra-hydrophobic water repellency in lotus leaf, directional water collection in wetted spider silk, directional adhesion in superhydrophobic butterfly wing, and fog-collecting hydrophobic/hydrophilic pattern on beetle back. These surfaces provide endless inspiration for the design and fabrication of functional interface materials with unique wettability, generating promising applications such as micro-fluidic devices, functional textiles, corrosion resistance, liquid transportation, antifogging, and water-collecting devices. In recent years there has been an exciting confluence of research areas of physics, chemistry, biology, and materials science to develop functional micro- and nanosurfaces. A kernel consists of organic materials with high/low surface energy and regular/irregular order/disorder, which can be rough/smooth and endlessly arranged and combined with various styles of micro- and nanostructures. This book introduces recent research on wettability of biological and bio-inspired surfaces. It discusses the mechanism of smart wetting controls, such as water collection/repellency on biological micro-/nanostructure gradient interfaces. It suggests ways to mimic these biological features to realize bio-inspired functional surfaces with unique wettability. The book will help researchers innovate designs with novel materials for future scientific works. Table of ContentsEffect of Lotus Leaves: Micro- and Nanostructure by Qunfeng Cheng;Effect of Butterfly Wing: Anisotropic Oriented Micro- and Nanostructure by Yongping Hou;Effect of Spider Silk: Gradient Micro- and Nanostructure by Yuan Chen; Effect of Beetle Back: Heterogenous wetting micro- and nanostructure pattern by Yuan Chen.
£109.25
Pan Stanford Publishing Pte Ltd Industrial Biocatalysis
Book SynopsisBiocatalysis has become an essential tool in the chemical industry and is the core of industrial biotechnology, also known as white biotechnology, making use of biocatalysts in terms of enzymes or whole cells in chemical processes as an alternative to chemical catalysts. This shift can be seen in the many areas of daily life where biocatalysts—with their environmentally friendly properties—are currently employed. Drivers are the big societal challenges resulting from concerns about the global climate change and the need for an assured energy supply. Modern biocatalysis relies to a large extent on the tremendous advances in the so-called omics techniques and the structural elucidation of biomolecules, which have led to synthetic biology and metabolic engineering as new research fields with high application potential for the rational design of enzymes and microbial production strains. In this book, renowned scientists discuss the actual developments in these research fields together with a variety of application-oriented topics.Trade Review"This book provides an actual and comprehensive overview of industrial biocatalysis, written by top scientists from academia and industry. It highlights by means of many examples how biocatalysis increasingly contributes to making the different areas of the chemical industry more sustainable through fostering an ongoing development towards a more bio-based economy. The book is highly recommended to all scientists active in this field as an excellent source for further inspirations and in addition should greatly assist academic lectures in this field."—Prof. Yasuhisa Asano, Toyama Prefectural University, JapanTable of ContentsBiocatalysts: global market, industrial applications, aspects of biotransformation design and societal challenges. Making use of newly discovered enzymes and pathways: reaction and process development strategies for synthetic applications with recombinant whole-cell biocatalysts and metabolically engineered production strains. Directed evolution of enzymes for industrial biocatalysis. Strategies to overcome constraints in enzyme evolution and facilitate effective enzyme engineering. Production of functional isoprenoids through pathway engineering. Metabolic engineering for the bio-based conversion of CO2 to biofuels. Mixed microbial cultures for industrial biotechnology: success, chance, and challenges. Extremophiles and their use in biofuel synthesis. Industrial applications of halophilic microorganisms. Non-pathogenic Pseudomonas strains as a platform for industrial biocatalysis. Use of Corynebacterium glutamicum for the production of high-value chemicals from new carbon sources. Applications of enzymes in industrial biodiesel production. Promiscuous biocatalysts: Applications for synthesis from the laboratory to industrial scale. Micro-magnetic porous and non-porous biocatalyst carriers. Robust enzyme preparations for industrial applications. Hydrolases in non-conventional media: Implications for industrial biocatalysis. Enreductases from cyanobacteria for industrial biocatalysis. Cytochrome P450 biocatalysts: current applications and future prospects. Laccases: green biocatalysts for greener applications. Lipase-catalyzed epoxidation of fatty compounds and alkenes. Synthetic potential of dihydroxyacetone uilizing aldolases. The hydantoinase process: recent developments for the production of non-canonical amino acids. Biotechnological approaches to dipeptide production. Synthetic enzyme cascades for valuable diols and amino alcohols: smart composition and optimization strategies. Metabolic engineering for the biosynthesis of longevity molecules rapamycin and resveratrol. Detergent proteases. Industrial starch processing. Algae: a rich source of energy and high-value products. Enzyme-catalyzed processes in a potential algal biorefinery. Biocatalytic synthesis of polymers: a contribution to green chemistry. Bio-based chemicals and materials.
£289.75
Pan Stanford Publishing Pte Ltd Tapping Molecular Wilderness: Drugs from
Book SynopsisThis book is for readers with some background in science, concerning the search for drugs, starting from molecular diversity in nature or molecular wilderness. Drug molecules may be used as such, or as starting points for improved drugs obtained from the interface of chemistry and biology. In some cases, the essential molecular features for drug properties from natural molecules may be identified and modified to more effective ones. In other cases, nature provides the targets, such as essential enzymes from infectious microorganisms, from which synthetic drugs can be designed. The mechanisms of action of drugs can be discerned by studying target–drug interactions. Nature may fight back, as in cases when microorganisms become resistant to drugs, but we can again use the chemistry–biology interface to obtain drugs which overcome the resistance. The battle goes on, hopefully with victory for both humans and balance of nature. This book differs from those available on the subject of natural products and drugs derived therefrom in that it looks at the broad picture on how materials and organisms from nature affect our health and how we have combined our knowledge in chemistry, biology, and biodiversity to promote our wellness from resources in the "molecular wilderness," with caveats on sustainable utilization of these resources. It is therefore suitable, not only for readers interested in science and medicine, but also for those with interest in policy issues concerning sustainable development, environment, and issues concerning interaction of science and society in general.Trade Review"Writing a popular science book is more challenging than writing a professional one for the technical audience. One needs to be scientifically rigorous, yet speak in the language of the school student and the ‘lay’ public. There can be no threatening equations or complex chemical pathways, yet one should convey the message in a lucid manner. Professor Yuthavong carries it off with ease and elan. He has chosen the word "wilderness" deliberately, to evoke both excitement and awe in the reader. He shows how human creativity is able to chisel molecules from wilderness into useful products, how nature itself has been doing such molecular architecture over evolution, and how we may learn from it. The underlying message, expressed with time honored wisdom, is Gandhian in spirit. Recall what Mahatma Gandhi said: ‘Nature provides for man’s need, but not his greed’, and ‘Be the change you want the world to be’. This is a book that needs to be distributed across both the developing and developed worlds." — D. Balasubramanian, Professor and Director of Research, L V Prasad Eye Institute, Hyderabad, India, and UNESCO Kalinga Prize Laureate in Science Popularization"I very much like the idea of writing something that's technically correct but intended for a general audience. The topics would correct an impression that all drug discovery these days comes from high throughput screening of synthetic molecules. I’m very impressed with the variety of topics the writer has managed to touch upon and with how technically accurate the handling of these topics has been."— Jon Clardy, Professor, Harvard Medical School and Broad Institute, USA"This pioneering book is a powerful source of enlightenment on the vital connections between the diversity world's biological splendour and advancement of scientific knowledge. It offers a convincing case as to why the conservation of biological diversity is imperative for human wellbeing. I recommend it to anyone who has an interest in sustainable development in general and environmental protection in particular."— Calestous Juma, Professor, Harvard Kennedy School, USA, and Former Executive Secretary, United Nations Convention on Biological Diversity"This is an excellent reading not only for researchers and students but also for general readers. The whole book is woven around the key term ‘wilderness’. It covers a wide area of subjects, from ancient myth to modern molecular biology and drug design. The book is not only educational but also highly entertaining. I hope in the future it will be available to those people who do not understand English."— Hisao Masai, Professor, Tokyo Metropolitan Institute of Science and University of Tokyo, Japan"The need to bring together new knowledge in basic sciences, agriculture, anecdotes and cultural norms on a single platform for efforts in prospecting for drugs from natural products cannot be overemphasized. Many have attempted to do this but only a few have the background necessary to succeed in the efforts. Professor Yongyuth brings with him a wealth of knowledge accumulated over thirty years and is probably the best to produce a much needed balanced view in the field."— Ayoade Oduola, Former Deputy Director, UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva, Switzerland"Professor Yongyuth Yuthavong has worked for decades at the highest levels of science and government and successfully cross pollinated these worlds. So it’s no surprise that his new book, Tapping Molecular Wilderness: Drugs from Chemistry–Biology–Biodiversity Interface, bridges the worlds of science and nature. Coming at the moment when the world is embarking on a new set of Sustainable Development Goals which also must embrace both science and nature, this book can be widely recommended for anyone who wishes to think more deeply about these goals—and the future of our world."— Peter Singer, Professor, University of Toronto, and Chief Executive Officer, Grand Challenges Canada"One thing that typifies the writer is his clarity in thinking and presentation: This quality is apparent in this highly readable book. Through hands-on drug research and involvement with related issues, he aims to make us appreciate nature for its cornucopia of simple and complex molecules that are beneficial to mankind. One such benefit is the natural products for combating pathogenic organisms whose drug resistance should be taken seriously by our making sustained and renewed efforts to fight them. After all pathogens must fight for their lives; simplistic and ephemeral efforts by the medical community have constantly proved to be inadequate. In this book the themes of the need to sustain nature for its biodiversity and to combat pathogens by natural and modified biomolecules shine through brilliantly."— Bhinyo Panijpan, Former Director, Institute for Innovative Learning, Mahidol University, Thailand"The author beautifully portraits the biodiverse ‘molecular wilderness’ as the world of wonder, full of treasure to benefit mankind. Complex chemistry of drug discovery and drug design is amazingly made simple. It ends with a strong message that molecular wilderness is powerful. We must respect its balance and coexist with it sustainably. Otherwise it fights back harshly. The book is very educational and inspiring. It is a complex scientific textbook neatly made simple for general readers. We definitely need more science and technology books in this literary style."— Khunying Sumonta Promboon, Member of Thai National Legislative Assembly and Former President of Srinakarinwirote University, Thailand"Living organisms produce both toxic compounds to disable their predators and beneficial compounds to protect or heal themselves, so as to enhance their ability to survive. So Nature, or the ‘Wilderness’, is a rich source of medically important molecules. Thus ‘Tapping the Molecular Wilderness’ has played a crucial role in the discovery of new drugs to combat human illnesses, such as infection and heart disease. The author elegantly discusses the principles of drug discovery, the need for an integrated role of chemistry and biology, novel strategies in research, as well as problems arising from drug resistance. As expert researcher, with success in devising a novel drug for malaria, the author has simplified the scientific concepts, historical perspectives and modern trends in drug discovery in a simplified manner, readily understood by the layman. More books like this are needed to show the importance of research, not only at applied level but also at basic level: Perhaps then governments, especially in developing countries, may invest more in research for the future."— M. R. Jisnuson Svasti, Emeritus Professor, Mahidol University and Chulaborn Research Institute, Thailand"The author should be admired for his bold effort to write a book on ‘natural science’ for the general public. As it turns out, this book not only contains a wealth of scientific information but also is very easy to read and to follow from the first page to the last. Readers will benefit from the knowledge given which can be used as a starting point to dig further into the ‘beauty of nature’. The author should be congratulated for the beautiful tale of science adventure."— Yodhathai Thebtaranonth, Emeritus Professor, Mahidol University, Thailand, and ASEAN Outstanding Technologist and Technologist Awardee, 1995"From the wilderness have come many revelations. Professor Yongyuth Yuthavong now has added chemistry to the list."— Prapon Wilairat, Professor, Mahidol University, Thailand, and Outstanding Scientist of Thailand Awardee, 1997Table of ContentsMolecular Wilderness Harsh and Healing. Gifts from Molecular Wilderness. Drug Targets from Molecular Wilderness. Molecular Wilderness as Templates for Drugs. The Wilderness Fights Back. Living with Molecular Wilderness.
£36.09
Pan Stanford Publishing Pte Ltd Polysaccharide Hydrogels: Characterization and
Book SynopsisHydrogels are an emerging area of interest in medicine as well as pharmaceutics, and their physico-chemical characterization is fundamental to their practical applications. Compared with synthetic polymers, polysaccharides that are widely present in living organisms and come from renewable sources are extremely advantageous for hydrogel formation. Furthermore, polysaccharides are usually non-toxic and biocompatible and show a number of peculiar physico-chemical properties that make them suitable for a wide variety of biomedical applications. This book bridges the gap between the preparation of hydrogels and their characterization techniques. It aims to offer a valid support that can help the readers find appropriate keys to open the doors to the complex world of polysaccharide hydrogels.Trade Review"This book unveils the secrets of polysaccharide hydrogels that make them invaluable tools in the biomedical field. It presents elegant approaches to preparing hydrogels, techniques for a very detailed characterization of polysaccharides and their hydrogels, and recent applications."— Prof. Carmen Alvarez-Lorenzo, University of Santiago de Compostela, Spain"This book is one of the first to cover all the aspects of polysaccharide hydrogels from the basic aspects of chemistry and characterization to their biological relevance and medical applications and is a great and comprehensive answer to the first questions concerning hydrogels."— Prof. Pierre Weiss, University of Nantes, France"‘The gel is easier to recognize than to define (Dorothy Jordan Lloyd, 1926). This book gives significant answers to this ‘old’ but still intriguing statement as it brings together most of the up-to-date information on the hot topic of hydrogels obtained from polysaccharides, and their preparation, characterization and application in the field of pharmaceutics."— Prof. Gaetano Giammona, University of Palermo and The Biophysics Institute, ItalyTable of ContentsIntroduction. Hydrogels. Rheological Characterization of Hydrogels. Hydrogel Mesh Size Evaluation. Dynamic Light Scattering. NMR Methodologies in the Study of Polysaccharides. Small-Angle Neutron Scattering of Polysaccharide Hydrogels. The Method of Small-Angle X-ray Scattering and Its Application to the Structural Analysis of Oligo- and Polysaccharides in Solution. Stimuli Responsive Polysaccharide-Based Hydrogels. Properties and Biomedical Applications of Gellan Gum Hydrogels. Polysaccharide Hydrogels with Magnetic Nanoparticles. Physical and Chemical Hyaluronic Acid hydrogels and Their Biomedical Applications. Alginate Hydrogels: Properties and Applications. Polysaccharide Hydrogels: The Present and the Future.
£133.00
Pan Stanford Publishing Pte Ltd Biocatalysis and Nanotechnology
Book SynopsisNanobiocatalysis has rapidly developed into a subarea of enzyme biotechnology. It combines the advances in nanotechnology that have generated nanoscale materials of different sizes, shapes, and physicochemical properties, and the excellent characteristics of biocatalysts into an innovative technology. This book provides an overview of the various relations between nanotechnology and biocatalysis. It discusses the fabrication and application of nanomaterials for the immobilization of enzymes used in the sustainable production of goods and chemicals. Nanosupports have several advantages compared with bulk solid materials because of their high surface area, which results in a significantly reduced mass transfer limitation and comparatively high enzyme loading. These characteristics are also of great use for applications in the fields of enzymatic biosensors, biofuel cells, bioelectronics, and photoelectrochemical analyte detection, where conductive nanomaterials improve the rate of electron transfer. The book also presents an overview of nanotoxicology and covers nanostructured enzyme catalysis in organic solvents and its potential application for biodiesel production, probing of enzymatic activity, and identification of enzyme functions of inorganic nanoparticles as enzyme mimics.Table of ContentsFundamentals of Nanotechnology. Biocatalysis: An Introduction. Environmentally Benign Nanomaterial Synthesis Mediated by Culture Broths. Rational Design of Enzyme-Polymer Biocatalysts. Biological Strategies in Nanobiocatalyst Assembly. Graphene-Based Nanobiocatalytic System. Immobilization of Biocatalysts onto Nanosupports: Advantages for Green Technologies. Enzyme Immobilization on Membrane and Its Application in Bioreactors. Potential Applications of Nanobiocatalysis for Industrial Biodiesel Production. Enzymogel Nanoparticles Chemistry for Highly Efficient Phase Boundary Biocatalysis. Recent Advances in Nanostructured Enzyme Catalysis for Chemical Synthesis in Organic Solvents. Probing Enzymatic Activity by Combining Luminescent Quantum Dots, Gold Nanoparticles and Energy Transfer. FRET Reporter Molecules for Identification of Enzyme Functions. Quantum Dot Architectures on Electrodes for Photoelectrochemical Analyte Detection. Inorganic Nanoparticles as Enzyme Mimics. Enzyme Nanocapsules for Glucose Sensing and Insulin Delivery. Nanostructured Materials for Enzymatic Biofuel Cells. Enzymatic Biofuel Cells on Porous Nanostructures. Nanoplasmonic Biosensors. Enzyme Biocomputing: Logic Gates and Logic Networks to Interface and Control Materials. Functional Nano-Bio Conjugates for Targeted Cellular Uptake and Specific Nanoparticle–Protein Interactions. Cell-Free Expression–Based Microarrays: Applications and Future Prospects. Overview of the Current Knowledge and Challenges Associated With Human Exposure to Nanomaterials.
£346.50
Pan Stanford Publishing Pte Ltd Nanomaterials for Direct Alcohol Fuel Cell
Book SynopsisDirect alcohol fuel cells (DAFCs), such as methanol and ethanol ones, are very promising advanced power systems that may considerably reduce dependence on fossil fuels and are, therefore, attracting increased attention worldwide. Nanostructured materials can improve the performance of the cathodes, anodes, and electrolytes of DAFCs. This book focuses on the most recent advances in the science and technology of nanostructured materials for direct alcohol fuel cells, including novel non-noble or low noble metal catalysts deposited on the graphene layer and metal-free doped carbon black for oxygen electroreduction reaction, Sn-based bimetallic and trimetallic nanoparticles for alcohol electro-oxidation reaction, and novel nanomaterials for promoting proton transfer in electrolytes. In addition, the book includes chapters from not only experimentalists but also computational chemists who have worked in the development of advanced power systems for decades.Illustrated throughout with excellent figures, this multidisciplinary work is not just a reference for researchers in chemistry and materials science, but a handy textbook for advanced undergraduate- and graduate-level students in nanoscience- and nanotechnology-related courses, especially those with an interest in developing novel materials for advanced power systems.Table of ContentsAdvanced Anode Catalysts for Direct Alcohol Fuel Cells Multimetallic Nanocatalysts for Anodic Reaction in Direct Alcohol Fuel Cell. Understanding Electrocatalytic Activity Enhancement of Bimetallic Nanoparticles to Ethanol Electro-oxidation Reaction. Theoretical Aspects of Gold Nanoparticles for Ethanol and Glucose Oxidation. Proton Transport and Design of Proton Electrolyte Membranes for Direct Alcohol Fuel Cells. Nanomaterials for Oxygen Reduction Reaction (ORR). Advances in Understanding the Effects on the Ethanol Electro-oxidation Reaction.
£94.04
Pan Stanford Publishing Pte Ltd Block Copolymer Nanocomposites
Book SynopsisThis book provides a comprehensive overview of the synthesis and characterization of nanocomposites based on block copolymers. Because of the self-assembly capability of block copolymers for the generation of nanostructures, besides their ability to nanostructure thermosetting matrices such as epoxy and polyester, binary or ternary nanocomposites can be prepared with different nanofillers such as nanoparticles and carbon nanotubes. The book starts with a review on nanocomposites based on block copolymers and nanoparticles synthesized with the use of surfactants, followed by a review on nanocomposites with metallic nanoparticles with polymer brushes and those with carbon nanotubes. A chapter is devoted to binary systems based on block copolymers and nanoparticles synthesized by sol-gel. A review on nanocomposites based on thermosetting matrices nanostructured with block copolymers (amphiphilic or chemically modified) is also presented for both epoxy and polyester resins. The work on ternary systems based on thermosetting matrices, block copolymers, and nanoparticles is presented next. The book concludes with a discussion on nanocomposites based on epoxy and block copolymers with azobenzene groups for optical purposes.Trade Review"This book includes a wide variety of examples of block copolymer nanocomposites and their applications. It documents the enormous progress made in the field in order to use very simple strategies to tailor the surface of nanoparticles into a block copolymer. The chapters are supplemented by comprehensive bibliographies. The book will be immensely useful for polymer chemists, engineers, metallurgists, and all those who are interested in materials science."—Prof. Deodato Radic, Pontificia Universidad Católica de Chile, ChileTable of ContentsSurfactant-treated nanoparticles confinement into block copolymer domains. Nanocomposites based on block copolymers and metallic nanoparticles grafted with polymer brushes. Nanocomposites based on block copolymers and carbon nanotubes. Block copolymer-assisted sol gel templating. Nanostructured epoxy based thermosetting materials modified with amphiphilic block copolymers. Chemically functionalized block copolymers as reactive modifiers for nanostructuring and toughening epoxy thermosetting materials. Nanostructuration of unsaturated polyester resins using block copolymers. Block copolymers as template for the design of advanced multifunctional hybrid nanostructured thermosetting materials. Reversible photoinduced birefringence in epoxy polymers, block copolymers and nanostructured thermosetting systems containing azobenzene groups.
£94.04
Yale University Press Fake Silk
Book SynopsisWhen a new technology makes people ill, how high does the body count have to be before protectives steps are taken?Trade Review“The book is well researched and clearly written, with a passionate concern for the impact of carbon disulphide on workers. . . this book will be very appealing to scholars as well as to general readers interested in the history of the rayon industry, the history of occupational health, or the unbridled use of toxic materials by industry.”—Peter Morris, Ambix"It is a fast paced and shocking tale. . . Rather than chart occupational health through a specific industry Fake Silk focuses on the substance, which permits a much broader and deeper reach into politics, economics, environmentalism and culture both in terms of both historical research and its audience."—Social History of Medicine“Action-packed . . . Reading Fake Silk, I could not help but wonder about the manufacturing process behind my T-shirt or the new dress hanging in my closet. Was someone harmed in the making of the kitchen sponge I just unwrapped?”—Science“Thanks to Paul Blanc’s extensively researched study we learn that. . . As the industry expanded, so did the number of victims suffering from the manufacturing process through exposure to the toxic solvent. They, as workers in the critical step, had suffered hallucinations and muscle and nerve dysfunction, and even died, from the toxic solvent carbon disulphide (disulfide). Their story is told sympathetically in this highly readable volume.” —Anthony S. Travis, Royal Society of Chemistry Historical Group Newsletter“In a time when many occupational physicians in developed countries will not see much classical occupational disease, this book is a timely reminder of the risks resulting from poorly controlled workplace exposures. Read it as a warning to understand the background to what happened in the viscose rayon industry and to quicken consciences for future prevention.”—Ron McCaig, Journal of Occupational Medicine“Interesting and engaging” —Catherine Mills, The Review of English Studies "This book provides a much needed dimension often missing in histories of rayon-producing corporations. . . .many readers will appreciate the assembling of facts concerning carbon disulfide's use."— Mary Schoeser, Textile History"Paul Blanc's book compellingly chronicles the all-too-real dangers behind the production of ‘fake’ silk. A terrifying exposé of what happens when the textile business puts profits before health."—Alison Matthews David, author of Fashion Victims:The Dangers of Dress Past and Present“This is an essential read for all interested in the history of occupational disease and of our increasing knowledge, yet failure to implement, the controls needed to reduce the risk of preventable disease and premature death.”—Sir Anthony Newman Taylor, Imperial College, London“Blanc's meticulous research has yielded a calm and overwhelming indictment of the murderous treatment that rayon workers worldwide have endured at the hands of their corporate masters.”—Eric Frumin, Health and Safety Director, US trade union federation Change to Win“A shocking story. Blanc draws back the curtain on the corporate deceit and neglect connected to products that have come to epitomize modern life.”— Frederick Rowe Davis, author of Banned: A History of Pesticides and the Science of Toxicology“A fascinating investigation into the colorful century-long history of a pernicious industrial hazard. A cautionary must-read for anyone who cares about eco-friendly living and integrity too.”—Don Katz, founder, Audible.com
£28.50
WW Norton & Co Textiles
Book SynopsisPractical information usually gained only through years of work experience and word of mouth is presented in this handbook for textile designers, students, interior designers and others who use textiles in their work.
£26.59
John Wiley & Sons Inc Pharmaceutical Biotechnology
Book SynopsisPharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals.Table of ContentsPreface. Acronyms. 1 Pharmaceuticals, biologics and biopharmaceuticals. 1.1 Introduction to pharmaceutical products. 1.2 Biopharmaceuticals and pharmaceutical biotechnology. 1.3 History of the pharmaceutical industry. 1.4 The age of biopharmaceuticals. 1.5 Biopharmaceuticals: current status and future prospects. 2 Protein structure. 2.1 Introduction. 2.2 Overview of protein structure. 2.3 Higher level structure. 2.4 Protein stability and folding. 2.5 Protein post-translational modifi cation. 3 Gene manipulation and recombinant DNA technology. 3.1 Introduction. 3.2 Nucleic acids: function and structure. 3.3 Recombinant production of therapeutic proteins. 3.4 Classical gene cloning and identifi cation. 4 The drug development process. 4.1 Introduction. 4.2 Discovery of biopharmaceuticals. 4.3 The impact of genomics and related technologies upon drug discovery. 4.4 Gene chips. 4.5 Proteomics. 4.6 Structural genomics. 4.7 Pharmacogenetics. 4.8 Initial product characterization. 4.9 Patenting. 4.10 Delivery of biopharmaceuticals. 4.10.3 Nasal, transmucosal and transdermal delivery systems. 4.11 Preclinical studies. 4.12 Pharmacokinetics and pharmacodynamics. 4.13 Toxicity studies. 4.14 The role and remit of regulatory authorities. 4.15 Conclusion. 5 Sources and upstream processing. 5.1 Introduction. 5.2 Sources of biopharmaceuticals. 5.3 Upstream processing. 6 Downstream processing. 6.1 Introduction. 6.2 Initial product recovery. 6.3 Cell disruption. 6.4 Removal of nucleic acid. 6.5 Initial product concentration. 6.6 Chromatographic purifi cation. 6.7 High-performance liquid chromatography of proteins. 6.8 Purifi cation of recombinant proteins. 6.9 Final product formulation. 7 Product analysis. 7.1 Introduction. 7.2 Protein-based contaminants. 7.3 Removal of altered forms of the protein of interest from the product stream. 7.4 Detection of protein-based product impurities. 7.5 Immunological approaches to detection of contaminants. 7.6 Endotoxin and other pyrogenic contaminants. 8 The cytokines: The interferon family. 8.1 Cytokines. 8.1.1 Cytokine receptors. 8.1.2 Cytokines as biopharmaceuticals. 8.2 The interferons. 8.3 Interferon biotechnology. 8.4 Conclusion. 9 Cytokines: Interleukins and tumour necrosis factor. 9.1 Introduction. 9.2 Interleukin-2. 9.3 Interleukin-1. 9.4 Interleukin-11. 9.5 Tumour necrosis factors. 10 Growth factors. 10.1 Introduction. 10.2 Haematopoietic growth factors. 10.3 Growth factors and wound healing. 11 Therapeutic hormones. 11.1 Introduction. 11.2 Insulin. 11.3 Glucagon. 11.4 Human growth hormone. 11.5 The gonadotrophins. 11.6 Medical and veterinary applications of gonadotrophins. 11.7 Additional recombinant hormones now approved. 11.8 Conclusion. 12 Recombinant blood products and therapeutic enzymes. 12.1 Introduction. 12.2 Haemostasis. 12.3 Anticoagulants. 12.4 Thrombolytic agents. 12.5 Enzymes of therapeutic value. 13 Antibodies, vaccines and adjuvants. 13.1 Introduction. 13.2 Traditional polyclonal antibody preparations. 13.3 Monoclonal antibodies. 13.4 Vaccine technology. 13.5 Adjuvant technology. 14 Nucleic-acid- and cell-based therapeutics. 14.1 Introduction. 14.2 Gene therapy. 14.3 Vectors used in gene therapy. 14.4 Gene therapy and genetic disease. 14.5 Gene therapy and cancer. 14.6 Gene therapy and AIDS. 14.7 Antisense technology. 14.8 Oligonucleotide pharmacokinetics and delivery. 14.9 Aptamers. 14.10 Cell- and tissue-based therapies. 14.11 Conclusion. Index.
£152.95
John Wiley & Sons Inc Pharmaceutical Biotechnology
Book SynopsisPharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals.Table of ContentsPreface. Acronyms. 1 Pharmaceuticals, biologics and biopharmaceuticals. 1.1 Introduction to pharmaceutical products. 1.2 Biopharmaceuticals and pharmaceutical biotechnology. 1.3 History of the pharmaceutical industry. 1.4 The age of biopharmaceuticals. 1.5 Biopharmaceuticals: current status and future prospects. 2 Protein structure. 2.1 Introduction. 2.2 Overview of protein structure. 2.3 Higher level structure. 2.4 Protein stability and folding. 2.5 Protein post-translational modifi cation. 3 Gene manipulation and recombinant DNA technology. 3.1 Introduction. 3.2 Nucleic acids: function and structure. 3.3 Recombinant production of therapeutic proteins. 3.4 Classical gene cloning and identifi cation. 4 The drug development process. 4.1 Introduction. 4.2 Discovery of biopharmaceuticals. 4.3 The impact of genomics and related technologies upon drug discovery. 4.4 Gene chips. 4.5 Proteomics. 4.6 Structural genomics. 4.7 Pharmacogenetics. 4.8 Initial product characterization. 4.9 Patenting. 4.10 Delivery of biopharmaceuticals. 4.10.3 Nasal, transmucosal and transdermal delivery systems. 4.11 Preclinical studies. 4.12 Pharmacokinetics and pharmacodynamics. 4.13 Toxicity studies. 4.14 The role and remit of regulatory authorities. 4.15 Conclusion. 5 Sources and upstream processing. 5.1 Introduction. 5.2 Sources of biopharmaceuticals. 5.3 Upstream processing. 6 Downstream processing. 6.1 Introduction. 6.2 Initial product recovery. 6.3 Cell disruption. 6.4 Removal of nucleic acid. 6.5 Initial product concentration. 6.6 Chromatographic purifi cation. 6.7 High-performance liquid chromatography of proteins. 6.8 Purifi cation of recombinant proteins. 6.9 Final product formulation. 7 Product analysis. 7.1 Introduction. 7.2 Protein-based contaminants. 7.3 Removal of altered forms of the protein of interest from the product stream. 7.4 Detection of protein-based product impurities. 7.5 Immunological approaches to detection of contaminants. 7.6 Endotoxin and other pyrogenic contaminants. 8 The cytokines: The interferon family. 8.1 Cytokines. 8.1.1 Cytokine receptors. 8.1.2 Cytokines as biopharmaceuticals. 8.2 The interferons. 8.3 Interferon biotechnology. 8.4 Conclusion. 9 Cytokines: Interleukins and tumour necrosis factor. 9.1 Introduction. 9.2 Interleukin-2. 9.3 Interleukin-1. 9.4 Interleukin-11. 9.5 Tumour necrosis factors. 10 Growth factors. 10.1 Introduction. 10.2 Haematopoietic growth factors. 10.3 Growth factors and wound healing. 11 Therapeutic hormones. 11.1 Introduction. 11.2 Insulin. 11.3 Glucagon. 11.4 Human growth hormone. 11.5 The gonadotrophins. 11.6 Medical and veterinary applications of gonadotrophins. 11.7 Additional recombinant hormones now approved. 11.8 Conclusion. 12 Recombinant blood products and therapeutic enzymes. 12.1 Introduction. 12.2 Haemostasis. 12.3 Anticoagulants. 12.4 Thrombolytic agents. 12.5 Enzymes of therapeutic value. 13 Antibodies, vaccines and adjuvants. 13.1 Introduction. 13.2 Traditional polyclonal antibody preparations. 13.3 Monoclonal antibodies. 13.4 Vaccine technology. 13.5 Adjuvant technology. 14 Nucleic-acid- and cell-based therapeutics. 14.1 Introduction. 14.2 Gene therapy. 14.3 Vectors used in gene therapy. 14.4 Gene therapy and genetic disease. 14.5 Gene therapy and cancer. 14.6 Gene therapy and AIDS. 14.7 Antisense technology. 14.8 Oligonucleotide pharmacokinetics and delivery. 14.9 Aptamers. 14.10 Cell- and tissue-based therapies. 14.11 Conclusion. Index.
£57.90
John Wiley & Sons Inc Process Dynamics and Control Modeling for Control
Book SynopsisOffering a different approach to other textbooks in the area, this book is a comprehensive introduction to the subject. Divided in three broad parts, the first part deals with building physical models, the second part with developing empirical models and the final part discusses developing process control solutions.Table of ContentsForeword. Preface. Acknowledgement. 1 Introduction to Process Modelling. 2 Process Modelling Fundamentals. 3 Extended Analysis of Modelling for Process Operation. 4 Design for Process Modelling and Behavioural Models. 5 Transformation Techniques. 6 Linearization of Model Equations. 7 Operating points. 8 Process Simulation. 9 Frequency Response Analysis. References. 10 General Process Behaviour 11 Analysis of a Mixing Process. 12 Dynamics of Chemical Stirred Tank Reactors. 13 Dynamic Analysis of Tubular Reactors. 14 Dynamic Analysis of Heat Exchangers. 15 Dynamics of Evaporators and Separators. 16 Dynamic Modelling of Distillation Columns. 17 Dynamic Analysis of Fermentation Reactors 18 Physiological Modeling: Glucose-Insulin Dynamics and Cardiovascular Modelling. 19 Introduction to Black Box Modelling. 20 Basics of Linear Algebra. 21 Data Conditioning. 22 Principal Component Analysis 23 Partial Least Squares 24 Time-series Identification. 25 Discrete Linear and Non-linear State Space Modelling. 26 Model Reduction. 27 Neural Networks. 28 Fuzzy Modelling. 29 Neuro Fuzzy Modelling. 30 Hybrid Models. 31 Introduction to Process Control and Instrumentation. 32 Behaviour of Controlled Processes. 33 Design of Control Schemes. 34 Control of Distillation Columns. 35 Control of a Fluid Catalytic Cracker. Appendix A. Modelling an Extraction Process. A1: Problem Analysis. A2: Dynamic Process Model Development. A3 Dynamic Process Model Analysis. A4 Dynamic Process Simulation. A5: Process Control Simulation. Hints. Index.
£151.16
John Wiley & Sons Inc Process Dynamics and Control
Book SynopsisOffering a different approach to other textbooks in the area, this book is a comprehensive introduction to the subject. Divided in three broad parts, the first part deals with building physical models, the second part with developing empirical models and the final part discusses developing process control solutions.Table of ContentsForeword. Preface. Acknowledgement. 1 Introduction to Process Modelling. 2 Process Modelling Fundamentals. 3 Extended Analysis of Modelling for Process Operation. 4 Design for Process Modelling and Behavioural Models. 5 Transformation Techniques. 6 Linearization of Model Equations. 7 Operating points. 8 Process Simulation. 9 Frequency Response Analysis. References. 10 General Process Behaviour 11 Analysis of a Mixing Process. 12 Dynamics of Chemical Stirred Tank Reactors. 13 Dynamic Analysis of Tubular Reactors. 14 Dynamic Analysis of Heat Exchangers. 15 Dynamics of Evaporators and Separators. 16 Dynamic Modelling of Distillation Columns. 17 Dynamic Analysis of Fermentation Reactors 18 Physiological Modeling: Glucose-Insulin Dynamics and Cardiovascular Modelling. 19 Introduction to Black Box Modelling. 20 Basics of Linear Algebra. 21 Data Conditioning. 22 Principal Component Analysis 23 Partial Least Squares 24 Time-series Identification. 25 Discrete Linear and Non-linear State Space Modelling. 26 Model Reduction. 27 Neural Networks. 28 Fuzzy Modelling. 29 Neuro Fuzzy Modelling. 30 Hybrid Models. 31 Introduction to Process Control and Instrumentation. 32 Behaviour of Controlled Processes. 33 Design of Control Schemes. 34 Control of Distillation Columns. 35 Control of a Fluid Catalytic Cracker. Appendix A. Modelling an Extraction Process. A1: Problem Analysis. A2: Dynamic Process Model Development. A3 Dynamic Process Model Analysis. A4 Dynamic Process Simulation. A5: Process Control Simulation. Hints. Index.
£55.05
John Wiley & Sons Inc LigandBinding Assays
Book SynopsisA consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs Trade Review"Ligand-Binding Assays, written by recognized and respected industry experts, covers a wide range of topics that provide valuable information to someone who is new to the field." (News & Analysis, 2011) "Ligand-Binding Assays, edited by Masood Kahn and John Findlay offers a comprehensive, in depth description of all aspects of the subject. The editors are directly involved in the ligand-binding assay field and individual chapters are written by experts with a thorough understanding of the specific topics. The book is easy to read, clear and well illustrated. The emphasis is on biologicals rather than small molecules and this reflects the current application of many of the procedures covered. There is a good overview of assay validation, and this book is highly recommended for those with an interest in the topic." —Robin Thorpe, PhD FRCPath, National Institute for Biological Standards and Control "This book is a collection of valuable articles describing these assays in some detail, both from a historical perspective ..., but also regarding the new developments in the field, such as new technologies to support drug development ... and pharmacokinetic research." (ChemMedChem, July 2010)Table of ContentsPreface. Contributors. 1 Ligand-Binding Assays in Drug Development: Introduction and Historical Perspective (John W.A. Findlay and Masood N. Khan). 1.1 General. 1.2 Historical Review. 1.3 LBAs for Macromolecules. 1.4 Advantages and Limitations of LBAs. 1.5 Ligand-Binding Assay Bioanalytical Focus Group of AAPS. 1.6 Scope of the Present Volume. References. 2 Ligand-Binding Assays to Support Disposition Studies of Macromolecular Therapeutics (Marian M. Kelley, Marjorie A. Mohler, and John W.A. Findlay). 2.1 Introduction. 2.2 Differences Between Low Molecular Weight Molecules and Macromolecules. 2.3 LBA Assay Considerations Relative to Research and Development Stage. 2.4 Critical Future Challenges for Ligand-Binding Assays. 2.5 Conclusions. References. 3 Development of Ligand-Binding Assays for Drug Development Support (Masood N. Khan, Proveen D. Dass, John H. Leete, Richard F. Schuman, Michele Gunsior, and Chanchal Sadhu). 3.1 Introduction. 3.2 Inherent Complexities of Immunoassay Development. 3.3 Steps in the Development of a Validatable Immunoassay. 3.4 Development and Optimization of an Immunoassay. 3.5 Optimization of Commercial Kit-Based Assays. 3.6 Troubleshooting Immunoassays. 3.7. Conclusions. Acknowledgments. References. 4 Validation of Ligand-Binding Assays to Support Pharmacokinetic Assessments of Biotherapeutics (Binodh S. DeSilva and Ronald R. Bowsher). 4.1 Introduction. 4.2 Assay Development and Validation Paradigm. 4.3 Prestudy Validation Phase. 4.4 Analytical Performance Characteristics. 4.5 In-Study Validation Phase. 4.6 Partial Validations/Method Transfer/Cross-Validation. 4.7 Documentation. 4.8 Conclusions. References. 5 Statistical Considerations in the Validation of Ligand-Binding Assays (Bruno Boulanger, Viswanath Devanarayan, and Walthère Dewé). 5.1 Introduction. 5.2 Objectives of Assay Validation. 5.3 Validation Criteria. 5.4 Estimating Assay Performance Characteristics. 5.5 Decision Rules and Risk Assessment in Prestudy Validation. 5.6 Decision Rules During In-Study Phase and Associated Risks. 5.7 Reconciling Validation and Routine Decision Rules. 5.8 Conclusions. References. 6 Development and Validation of Ligand-Binding Assays for Biomarkers (Jean W. Lee, Yang Pan, Peter J. O’Brien, and Ren Xu). 6.1 Introduction. 6.2 Preanalytical Considerations and Method Feasibility. 6.3 Method Development and Method Qualification for Exploratory Applications. 6.4 Method Development and Method Validation for Advanced Applications. 6.5 Partial Validation for Change Control. 6.6 Documentation, Record Keeping, and Reporting. 6.7 Regulatory Issues. 6.8 In-study Validation. 6.9 Conclusions. Acknowledgments. References. 7 The Use of Commercial Assay Kits for PK/PD Analysis in Drug Development (John L. Allinson and John D. Chappell). 7.1 Introduction. 7.2 Validation Definitions That May be Interpreted Inconsistently. 7.3 Validation Experiments. 7.4 Stability. 7.5 Reoptimizing Reagent Concentrations. 7.6 The Use of Commercial Kits for PK and TK Assays. 7.7 Matrix Problems. 7.8 Changing Method Protocol. 7.9 Conclusions. References. 8 Development and Validation of Immunogenicity Assays for Preclinical and Clinical Studies (Thomas H. Parish, Deborah Finco, and Viswanath Devanarayan). 8.1 Introduction. 8.2 Immunogenicity Risk-Based Strategy. 8.3 Regulatory Guidance. 8.4 Assay Design. 8.5 Optimization and Validation: Total Binding Antibody Assays. 8.6 Optimization and Validation: Neutralizing Antibody Assays. 8.7 Assays and Risk Assessment. 8.8 Application and Interpretation of Data. 8.9 Conclusions. 8.10 Appendix 8.A Illustration of Screening Cut Point Evaluation. References. 9 Macromolecular Reference Standards for Biotherapeutic Pharmacokinetic Analysis (Marie T. Rock and Stephen Keller). 9.1 Introduction. 9.2 United States Pharmacopeia. 9.3 Characterization of Non-USP Reference Standards. 9.4 The PK Assay. 9.5 Conclusions. References. 10 Strategies for Successful Transfer of Ligand-Binding Assays for Successful Validation and Implementation in GXP Environment (Wolfgang Klump and Howard Hill). 10.1 Introduction. 10.2 Establishing Successful Working Relationships Between Laboratories. 10.3 Method Transfer. 10.4 Monitoring the Method Transfer Process. 10.5 Auditing CROs. 10.6 Method Troubleshooting. 10.7 Secrets of Successful Method Transfer. Acknowledgments. References. 11 Application of Automation in Ligand-Binding Assays (Chris Morrow). 11.1 Introduction. 11.2 Implementing Automated Systems. 11.3 Specific Ligand-Binding Assay Automation Systems. 11.4 Automated Sample Dilutors. 11.5 Assay Robots. 11.6 Integration: Tying It All Together. 11.7 Future Directions in Ligand-Binding Assay Automation. 11.8 Conclusion. Acknowledgments. References. 12 Documentation and Regulatory Compliance (CT. Viswanathan and Jacqueline A. O’Shaughnessy). 12.1 Regulatory Perspectives in the Documentation of Bioanalytical Data and Reports. 12.2 Recommendations for Development, Validation, Implementation, and Reporting Phases. 12.3 Conclusions. References. 13 Alternative and Emerging Methodologies in Ligand-Binding Assays (Huifen F. Wang and John W.A. Findlay). 13.1 Introduction. 13.2 Dissociation-Enhanced Lanthanide Fluoroimmunoassay. 13.3 Enzyme-Linked Immunospot Assay. 13.4 Immuno-Polymerase Chain Reaction. 13.5 Electrochemiluminescence-Based Ligand-Binding Assays. 13.6 Hybridization-Based Ligand-Binding Assays. 13.7 Molecularly Imprinted Polymers (Synthetic Antibodies). 13.8 Surface Plasmon Resonance Methods. 13.9 Chromatography–Ligand-Binding Assay Coupled Methods, Immunoaffinity Systems, and Online (Flow-Injection) Ligand-Binding Assay Methods. 13.10 Future Trends and Directions for LBATechnologies. 13.11 Conclusions. Acknowledgment. References. Index.
£109.76
John Wiley & Sons Inc Combination Drug Products
Book SynopsisA step-by-step, integrated approach for successful, FDA-approved combination drug products Using a proven integrated approach to combination drug development, this book guides you step by step through all the preclinical, clinical, and manufacturing stages.Table of ContentsPreface xi Acknowledgments xiii Contributors xv 1 Overview of Combination Products Development and Regulatory Review 1 Evan B. Siegel 2 Detailed Regulatory Approaches to Development, Review, and Approval 5 James Barquest 2.1 Introduction 5 2.2 General Background 6 2.2.1 Definitions 6 2.2.2 FDA Organization and Jurisdiction 7 2.2.3 Clinical Investigation and Premarket Review Requirements for Drugs, Biological Products, and Medical Devices 11 2.2.4 FDA Information Resources 15 2.3 Combination Products: Regulatory Background 16 2.3.1 Definition 16 2.3.2 Intercenter Agreements 18 2.3.3 Office of Combination Products 19 2.3.4 Primary Mode of Action 20 2.3.5 Intended Use 30 2.3.6 Strategic Regulatory Considerations 31 2.3.7 The Request for Designation (RFD) Process 34 2.3.8 User Fees 44 2.3.9 FDA Meetings: Successful Regulatory Interactions 50 2.3.10 Current Good Manufacturing Practice for Combination Products 59 2.4 Postmarketing Considerations 67 2.4.1 Adverse Event Reporting 68 2.4.1.1 Device Malfunction Reporting (21 CFR 803.3(r)(2)(ii), 21 CFR 803.20) 68 2.4.1.2 Five-Day MDR Reporting (21 CFR 803.10(c)(2)(i)) 68 2.4.1.3 Drug and Biological Product “Alert” Reporting (21 CFR 314.80(c)(1) and 600.80(c)(1)) 73 2.4.1.4 Blood-Related Deaths (21 CFR 606.170) 73 2.4.2 Other Compliance Issues 73 References 74 3 Nonclinical Recommendations for Successful Characterization and Development of Combination Drug Products 77 Duane B. Lakings 3.1 Introduction 77 3.2 Pharmacology 79 3.2.1 Pharmacology and Safety Pharmacology Recommendations for CDPs with Multiple Marketed Drugs 80 3.2.2 Pharmacology and Safety Pharmacology Recommendations for CDPs with Marketed Drugs and a Single NME 83 3.2.3 Pharmacology and Safety Pharmacology Recommendations for CDPs with More Than One NME 83 3.3 Pharmacokinetics 84 3.3.1 Pharmacokinetic and Drug Metabolism Recommendations for CDPs with Multiple Marketed Drugs 89 3.3.2 Pharmacokinetic and Drug Metabolism Recommendations for CDPs with Marketed Drugs and a Single NME 91 3.3.3 Pharmacokinetic and Drug Metabolism Recommendations for CDPs with More Than One NME 91 3.4 Toxicology 92 3.4.1 Toxicology Recommendations for CDPs with Multiple Marketed Drugs 98 3.4.2 Toxicology Recommendations for CDPs with Marketed Drugs and a Single NME 102 3.4.3 Toxicology Recommendations for CDPs with More Than One NME 104 3.5 Conclusions 108 References 109 4 Clinical Pharmacology and Clinical Development of Combination Products 113 Chaline Brown 4.1 Introduction 113 4.2 Postapproval Clinical Safety Reporting 115 4.3 Clinical Development of Drug–Delivery System Combination Products 116 4.3.1 Advantages of a New Delivery Device Drug Product 117 4.3.1.1 Streamlined Regulatory Process Possible 117 4.3.1.2 Improvement in Efficacy over Previously Approved Delivery Routes 117 4.3.1.3 Noninjection Bioavailability for Peptides and Proteins 118 4.3.2 Considerations for a Combination Product with a Novel Delivery Route 119 4.3.2.1 Impact of Infusion Pumps on Pharmacodynamic Effects 119 4.3.2.2 Route-Dependent Pharmaceutical Metabolic Profile 119 4.3.2.3 Inherent Delivery Site Sensitivity 119 4.3.2.4 Addressing Concerns Regarding the Safety of Excipients in Novel Routes of Delivery 120 4.3.2.5 Addressing Concerns of Possible Immune System Reactions During Development 120 4.3.2.6 Addressing Effects Specific to Human Physiology During Development 120 4.3.2.7 Addressing Formulation Changes During Clinical Development 121 4.3.3 Case Study: Exubera® (Pfizer’s inhaled insulin, approved January 2006) 121 4.4 Clinical Development of Drug–Active Device Combination Products 127 4.4.1 Case Study: The Drug-Eluting Stent (DES) 128 4.4.2 Changing Scene for New DES Products 132 4.5 Clinical Development of Co-Packaged Combination Products 134 4.5.1 Co-Packaged Drug and Biologic Case Study: Interferon and Ribavirin for the Treatment of Hepatitis C 135 4.6 Clinical Development of Drug–In Vitro Diagnostic Combination Products 140 4.6.1 Retrospective Changes in Drug Labeling to Incorporate Genetic Tests 143 4.6.2 Prospective Co-Development of Drugs and In Vitro Diagnostics 144 4.6.3 Issues Surrounding Biomarker Development 146 4.6.4 Clinical Trial Design Issues in Drug–In Vitro Diagnostic Co-Development 147 4.6.5 FDA Guidance 149 4.6.6 Case Study: Herceptin® and HercepTest® 150 4.7 Clinical Development of Drug–Biologic Combination Products 153 4.7.1 Case Study 1: Mylotarg® (Monoclonal Antibody Linked to a Cytotoxic Drug) 154 4.7.2 Case Study 2: Bexxar® (Monoclonal Antibody Linked to a Radioisotope) 157 4.8 Clinical Development of Drug–Drug Combinations 160 4.8.1 General Considerations for FDC Efficacy Studies 162 4.8.2 Case Study: CombinatoRx, with Combination Therapy as a Business Model 163 4.9 Conclusion 165 References 165 5 Regulatory Strategy Considerations for Chemistry, Manufacturing, and Controls: An Integrated Approach 171 Patrick L. DeVillier 5.1 Introduction 171 5.2 Office of Combination Products (OCP) and Request for Designation (RFD) 172 5.3 Extent of Regulatory Oversight 173 5.4 Investigational Device Exemption and Investigational New Drug Exemption 174 5.5 Regulatory Compliant Product Development 175 5.6 Chemistry, Manufacturing, and Controls Review Requirements 177 5.7 Drug Component Requirements 178 5.8 Device Component Requirements 179 5.9 Sterilization Considerations 179 5.10 Stability Considerations 180 5.11 Bench Testing and Early Development Considerations 180 5.12 CDP Regulatory Cross-Mapping Guidance and Recommendations 181 5.13 Conclusions 200 References 200 List of Abbreviations 201 Index 205
£86.36
John Wiley & Sons Inc 28th International Conference on Advanced
Book SynopsisA collection of Papers Presented at the 28th International Conference and Exposition on Advanced Ceramics and Composites held in conjunction with the 8th International Symposium on Ceramics in Energy Storage and Power Conversion Systems.
£99.86
John Wiley & Sons Inc 28th International Conference on Advanced
Book SynopsisA collection of Papers Presented at the 28th International Conference and Exposition on Advanced Ceramics and Composites held in conjunction with the 8th International Symposium on Ceramics in Energy Storage and Power Conversion Systems.Table of ContentsPreface. MECHANICAL PROPERTIES OF ENGINEERING CERAMICS, COMPOSITES AND AEROSPACE MATERIALS. Properties of Rare Earth Oxynitride Glasses and the Implications for High Temperature Behaviour of Silicon Nitride Ceramics (S. Hampshire and M. J. Pomeroy). Mechanical Properties of Porous Silicon Nitride From Fine/Coarse Powder Mixture (M. Ishizaki, M. Ando, N. Kondo and T. Ohji). Production and Characterization of Ultra Refractory HfB2-SiC Composites (F. Monteverde and A. Bellosi). Sintering Behaviour of Dense Nanocrystalline Zirconia Ceramics: A Comparative Investigation (M. Wolff, G. Falk and R. Clasen). Direct Evaluation of Local Thermal Conduction in Silicon Nitrides with Enhanced Grain Growth (A. Okada and T. Hori). Mechanical Properties of Pressureless Sintered SiC-AIN Composites Obtained Without Sintering Bed (C. Magnani and L. Beaulardi). The Influence of Beta Eucryptite Glassceramics on the Structure and Main Properties of Alumina Ceramics (J. A. Geodakyan, A. K. Kostanyan, K. J. Geodakyan, S. T. Sagatelyan and B. V. Petrosyan). Mechanical Behaviour of SiC-Polycrystalline Fiber-Bounded-Ceramics (S. Kajii, K. Matsunaga, M. Sato and T. Ishikawa). Design, Manufacture and Quality Assurance of C/C-SiC Composites for Space Transportation Systems (W. Krenkel, J. L. Hausherr, T. Reimer and M. Frieß). Effect of Fabrication Process on Internal Friction of SiC/SiC Composites (H. Serizawa, S. Sato, H. Araki, T. Noda and A. Kohyama). Effect on Interphase on Transthickness Tensile Strength of High Purity Silicon Carbide Composites (T. Hinoki, Y. Maki, A. Kohyama, E. Lara-Curzio and L. L. Snead). Through-Thickness Properties of 2D Woven SiC/SiC Panels with Various Microstructures (H. M. Yun and J. A. Carlo). An Assessment of Variability in the Average Tensile Properties of a Melt-Infiltrated SiC/SiC Composite (S. Kalluri, A. M. Calomino and D. N. Brewer). Net Shape Manufacturing of Fabric Reinforced Oxide/Oxide Components via Resin Transfer Moulding and Pyrolysis (B. Heidenreich, W. Krenkel, M. Frieß and H. Gedon). In Situ Reaction Deposition Coating of LaPO4 ON Al2O3 Fabric Cloth for Al2O3/Al2)O3 Composites (T. Yano, P. Lee and M. Imai). Effect of Alkali Choice on Geopolymer Properties (W. M. Kriven and J. L. Bell). Thermal Shock Resistance of NEXTEL™610 and NEXTEL™720 Continuous Fiber-Reinforced Mullite Matrix Composites (R. A. Simon and P. Supanic). Tensile Properties of Nextel™ 720-Based Tows and Minicomposites Subjected to High Temperature Soaking (D. M. Pai, S. Yarmolenko, B. Kailasshankar, C. Murphy, J. Sankar and L. P. Zawada). Effect of Monazite Coating on Tensile Behavior of Nextel™ 720 Fibers at High Temperature (D. M. Pai, S. Yarmolenko, E. Freeman, J. Sankar and L. P. Zawada). BN Interphase Processed by LP-CVD from Tris(Dimethylamino) Borane and Characterized Using SiC/SiC Minicomposites (S. Jacques, B. Bonnetor, M. –P. Berthet and H. Vincent). Oxidation Kinetics and Strength Degradation of Carbon Fibers in a Cracked Ceramic Matrix Composite (M. C. Habig). Mechanical Behavior and Oxidation-Resistance of an Orthogonal 3D δ-SIC Fiber/Carbon Matrix Composite (T. Aoki, T. Ogasawara and T. Ishikawa). Mechanical Properties of Ceramic Matrix Composites Exposed to Rig Tests (G. Y. Richardson, C. S. Lei and R. N. Singh). Composition and Microstructural Design for Improved Wear Properties in SiAION Ceramics (M. I. Jones, K. Hirao, Y. Yamauchi and H. Hyuga). Plasma-Treated Silicon Nitrides Exhibiting Ultra-Low Friction (A. Okada, T. Hori, K. Ueoka and J. Ye). Tribiological Properties of Si2N4 / Si3N4-BN Alternate Layered Composites (T. Hirao, K. Hirao and Y. Yamauchi). A Motorcycle Brake System with C/C-SiC Composite Brake Discs (Z. Stadler, M. Kermc, T. Kosma-, and A. Dakskobler). The Tribological Property Effect of Graphite Within a Composite Pad-Cost Iron Baking System (S. Ramouse). High Performance C/C-SiC Brake Pads (W. Krenkel, H. A. El-Hija and M. Kriescher). Sliding Contact Damage of Y- α/β Composite SiALON Ceramics (W. Kanematsu, M. I. Jones and K. Hirao). Processing and Wear Behavior of Cr-Al2O3-ZrO2 and Mo-Al2)3-ZrO2 Composites (R. Janssen, S. Scheppokat, G. De Portu, R. Hannink and N. Claussen). Improving Performance of Polycrystalline Diamond Components in Three Cone Roller Bits Uisng Bibrous Monolith Technology (A. Griffo and D. Belnap). Enhancement of the Fracture Resistance on SiC Fiber (Nicalon™)/SiC Refractory Composites (T. Tanaka, H. Ichikawa, S. Fukumaru and H. Abe). Critical Frontal Process Zone Evaluation of Aluminum Titanate/Aluminia Based Ceramics by SEVNB Technique (C. –H. Chen and H. Awaji). Atomistic Study of Crack Propagation Near the Cu(111)/Al2O3(0001) Interface (S. V. Dmitriev, N. Yoshikawa, M. Hasegawa, Y. Kagawa, M. Kohyama and S. Tanaka). Sensitivity of Silicon Carbide and Other Ceramics to Edge Fracture: Method and Results (G. Gogotsi, S. Mudrik and A. Rendtel). Determination of Elastic Properties of a Ceramic-Based Joint Using a Digital Image Correlation Method (M. Puyo-Pain and J. Lamon). Evaluation of Four Different Experimental Techniques for Determination of Elastic Properties of Solids (M. Radovic, E. Lara-Curzio and L. Riester). Strength Testing System for Ceramic Grains (K. Breder, E. Lara-Curzio and L. Riester). Characterization of C/Enhanced SiC Composite During Creep Rupture Tests Using an Ultrasonic Guided Wave Scan System (D. J. Roth, M. J. Verrilli, R. E. Martin and L. M. Cosgriff). Design of a High Temperature Test Device for Bidirectional Loading for CMC Samples (I. Fischer, T. Reimer and H. Weihs). Biaxial Strength Test of Discs of Different Size Using the Ball on Three Balls Test (A. Börger, R. Danzer and P. Supancic). Atomic Force Microscopy Study of the Surface Degradation Mechanisms of Zirconia Based Ceramics (S. Deville, J. Chevalier, G. Fantozzi, J. F. Bartolomé and J. S. Moya). Internal Pressure Testing of Structural Ceramics Tubes (R. H. Carter and J. J. Swab). Characterization of Si³N4 Bars Extracted From Various Regions of a Billet by Resonance and Flex Testing (G. Ojard, M. Ferber, T. Barnett and K. Johnson). Laser Scattering Characterization of Subsurface Defect/Damage in Silicon-Nitride Ceramic Valves (J. G. Sun, J. M. Zhang and M. J. Andrews). A Model for the Bulk Mechanical Response of Porous Ceramics Exhibiting a Ferroelectric-to-Antiferroelectric Phase Transition During Hydrostatic Compression (S. T. Montgomery and D. H. Zeuch). Random Local Load Sharing in Multifilament Bundles: Modeling and Influence on Ceramic Matrix Composite Failure (V. Calard and J. Lamon). Experimental and Numerical Fluid Structure Investigations of a Generic Bodyflap Region Model (R. Schaefer, A. Mack, B. Esser and A. Guelhan). ADVANCED CERAMIC COATINGS FOR STRUCTURAL, ENVIRONMENTAL AND FUNCTIONAL APPLICATIONS. Ultra-High-Temperature Tribometer up to 1600°C (M. Gienau, N. Kelling, N. Köhler and M. Woydt). Erosion of Bare and Coated Polymer Matrix Composites by Solid Particle Impingement (K. Miyoshi, J. K. Sutter, R. A. Horan, S. K. Naik and R. J. Cupp). The Effect of Thermal Mismatch on Stresses, Morphology and Failures in Thermal Barrier Coatings (J. Shi, S. Darzens and A. M. Karlsson). Mechanically Induced Delamination Cracking in Thermal Barrier Composites (T. Wakui, J. Malzbender, E. Wessel, R. W. Steinbrech and L. Singheiser). Investigation of Thermal Fatigue Life of Thermal Barrier Coating (Y. Ohtake and T. Natsumura). Evaluation of Two New Thermal Barrier Coating Materials Produced by APS and EB-PVD (B. Saruhan, U.Schultz, R. Vassen, G. Pracht, P. Bengtsson, C. Friedrich, R. Knoedler, O. Lavigne, P. Moretto, C. Siry, F. Taricco, N. Coignard and R. Wing). Low Thermal Conductivity Ceramics for Turbine Blade Thermal Barrier Coating Application (U. Schulz, B. Saint-Ramond, O. Lavigne, P. Moretto, A. vanLieshout and A. Berger). Solution Precursor Plasma Spray: A Promising New Technique for Forming Functional Nanostructured Films and Coatings (X. Ma, J. Roth, T. D. Xiao, L. D. Xie, M. Gell, E. H. Jordan and N. P. Padture). Further Improvement of the Properties of Sprayed TBC Using Hollow PSZ Spheres (G. Bertrand, P. Roy, C. Meunier, M. Mévrel and D. Demange). Effect of Bond Coat Surface Roughness and Pre-Oxidation on the Thermal Cycling Lifetime of Thermal Barrier Coatings (J. Liu and Y. H. Sohn). Chemical Etching of Silicon Carbide Ceramic Surface in Chlorine-Containing Gas Mixtures (A. V. Zinovev, J. F. Moore, J. Hryn, O. Auciello, J. Carlisle and M. J. Pellin). Micromechanisms Affecting Macroscopic Deformation of Plasma-Sprayed TBCs (E. Trunova, R. Herzog, T. Wakui, R. W. Steinbrech, E. Wessel and L. Singheiser). Stability of Silicon Nitride Coated with Lutetium Disilicate in an Oxidative Environment (T. Suetsuna, M. Ando, M. Ishizaki, T. Ohji and M. Asayama). Effect of Scattering on the Combined Reflection and Thermal Radiation Emission of a Typical Semitransparent TBC Material (C. M. Spuckler). Behavior of Sputter Deposited Aluminia Thin Films Under Subcritical Hydrothermal Condition (S. T. Park and R. H. Baney). Stability and Performance of High Emissivity Coatings for Radiation Coupled Thermionic Converters (P. N. Clark, B. H. C. Chen, W. H. Robertson and H. H. Streckert). Functionally Graded CVD Mullite Environmental Barrier Coatings (S. N. Basu and V. K. Sarin). Corrosion Mechanism of Lu2Si2O7 Phase in Static State Water Vapor Environment (S. Ueno, D. D. Jayaseelan, N. Kondo, T, Ohji and S. Kanzaki). Examination of Fracture Process and Environmental Resistance of Ceramic Matrix Composites (SiC/SiC) (M. Okada, I. Yuri, T. Hisamatsu, A. Nitta, T. Kameda and Y. Yasutomi). Corrosion of Ceramic Materials in Hot Gas Environment (H. Klemm, M. Fritsch and B. Schenk). Optimizing Cu-Cr Coatings for Environmental Protection of Copper Alloys (L. Ogbuji). Characterization of Y2O3-Doped La2Zr2O7 Based EB-PVD Thermal Barrier Coatings Using X-Ray Microtomography (CMT) and Small Angle Neutron Scattering (SANS) (B. Saruhan, A. Flores Renteria, A. Kulkarni, F. DeCarlo and J. Ilavsky). Growth of Thermally Grown Oxide on (Ni,Pt)Al Bondcoat During Short Term Oxidation (S. Laxman, Y. H. Sohn and K. S. Murphy). Measuring and Modeling Residual Stresses in Air Plasma Spray Thermal Barrier Coatings (X. Chen, J. Price and J. Ahmad). Formation of Environmental Barrier Coating on Si3N4 by Gas Pressure Sintering (D. D. Jayaseelan, S. Ueno, N. Kondo, T. Phji and S. Kanzaki). BOMATERIALS AND BIOMEDICAL APPLICATIONS. Wear of a Bioceramic Dental Restorative Material by Tooth Brushing (A. Pallas, H. Engqvist, L. –Å. Lindén and L. Hermansson). Depth-Profiling of Composition and Texture in Human Tooth Enamel – A Functionally Graded Material (I. M. Low). Morphologies of Precipitate in the Carbonate Plus Phosphate Aquenos Solution (W. –Y. Huang and T. –S. Sheu). Calcium Phosphate Ceramics as Substrate for Cartilage Cultivation (R. Janssen, S. Nagel-Heyer, C. Goepfert, R. Pörtner, D. Toykan, O. Krummhauer, M. Morlock, P. A. Adamietz, N. M. Meenen, W. M. Kriven, D. –K. Kim, A. Tampieri and G. Gelotti). Resorbable Polymer Ceramic Composites for Orthopedic Scaffold Applications (R. Vaidyanathan, B. Hecht, A. Studley, T. Phillips and P. D. Calvert). Nanoceramics as Drug Delivery Carriers (W. M. Kriven, S. –Y. Kwak, R. B. Clarkson, B. E. Kitchell, M. A. Wallig and J. –H. Choy). Chemical Processing of Brushite its Conversion to Apatite OR CasP2O7 (A. Cuneyt Tas and S. B. Bhaduri). Chemical Interactions Between Ca-Aluminate Implants and Bone (H. Engqvist, M. Couillard, G. A. Botton, N. Axén, N. O. Ahnfelt and L. Hermansson). Fabrication of Novel Hydroxyapatite/Titanium Composite Coating using rf Reactive Plasma Spraying (Y. Yokogawa, M. Inagaki and T. Kameyama). Manufacturing of Ceramic Dental Components by Means of Electrophoretic Deposition (C. Oetzel, J. Tabellion and R. Clasen). New and Conventional Simulated Body Fluids (H. Takadama, M. T. Hashimoto, Y. Takigawa, M. Mizuno and T. Kokubo). Scratch Testing of a Dental Restorative Material Based on Calcium Aluminate (A. Pallas, H. Engqvist, S. Jacobsson and L. Hermansson). NANOMATERIALS AND BIOMIMETICS. Near-Shape Manufacturing of Complex Silica Glasses by Electrophoretic Deposition of Mixtures of Nanosized and Coarser Particles (J. Tabellion and R. Clasen). Alumina Ceramics by Means of Electrophoretic Deposition of Submicron Powders (A. Braun, M. Wolff, C. Oetzel, J. Tabellion, G. Falk and R. Clasen). Influence of the Synthesis Temperature on the Crystallization Path and Kinetics of YAG Powders (P. Palmero, L. Montanaro, C. Esnouf and G. Fantozzi). High Strenth SiSIC Ceramics Derived From Wood Powders (A. Hofenauer, O. Treusch, F. Tröger, M. Gahr, J. Schmidt, G. Wegener, W. Krenkel and J. Fromm). Development of Screen Printable Sensors with Templated Mesoporous Silica (A. Lindqvist, M. Arenö and E. Carlström). Synthesis and Characterization of Sol-Gel Derived Nanostructured Composite of ZnO/PVP Thin Film as Biosensor (T. Du, H. Song and O. J. Ilgebusi). Microwave Plasma Chemical Vapor Deposition (CVD) of Carbon Based Films in the System C-N (R. Ramamurti, R. S. Kukreja, L. Guo, V. Shanov and R. N. Singh). Manufacturing of Thick Layers Made From Nanosized SiO2 Powders by Dip-Coating (G. Fehringer and R. Clasen). Mechanical Properties of Ni Embedded Alumina Nanocomposite Thin Films (S. Neralla, D. Kumar, S. Yamolenko and J. Sankar). Synthesis and Crystal Phase Evaluation of Hydroxylapatite Using the Rietveld Maximum Entropy Method (A. V. Chaves de Andrade, J. C. Zurita da Silva, C. O. Paiva-Santos, C. Weber, V. Hizau dos Santos Utuni, S. Mazurek Tebcherani, C. P. Ferreira Borges, E. da Costa and S. Martinez Manent). Processing and Hardness of an Al2O3-MgAl2O4 Nanocomposite (B. W. McEnerney, G. Quinn, V. A. Greenhut, R. K. Sadangi, V. Shukla, B. Kear and D. E. Niesz).
£99.86
John Wiley & Sons Inc Synthesis and Processing of Nanostructured
Book SynopsisAdvances in nanotechnology offer great new promise in new multifunctional systems that experts predict to be a major economic force within the next decade. Ceramic materials enable new developments in such areas as electronics and displays, portable power systems and personnel protection.Table of ContentsPreface. Introduction. Nanoparticle Colloidal Suspension Optimization and Freeze-Cast Forming (Kathy Lu and Chris S. Kessler). Synthesis, Characterization and Measurements of Electrical Properties of Alumina-Titania Nano-Composites (Vikas Somani and Samar J. Kalita). Synthesis and Characterization of Nanocrystalline Barium Strontium Titanate Ceramics (Vikas Somani and Samar J. Kalita). Nanoparticle Hydroxyapatite Crystallization Control by using Polyelectrolytes (Mualla dner and dzlem Dogan). Synthesis of Carbon Nanotubes and Silicon Carbide Nanofibers as Composite Reinforcing Materials (Hao Li, Abhishek Kothari, and Brian W. Sheldon). 3-D Microparticles of BaTiO, and Zn,SiO, via the Chemical (Sol-Gel, Acetate, or Hydrothermal) Conversion of Biological (Diatom) Templates (Ye Cai, Michael R. Weatherspoon, Eric Ernst, Michael S. Haluska, Robert L. Snyder, and Kenneth H. Sandhage) Polymer Fiber Assisted Processing of Ceramic Oxide Nano and Submicron Fibers (Satyajit Shukla, Erik Brinley, Hyoung J. Cho, and Sudipta Seal). Phase Development in the Catalytic System V205/Ti02 under Oxidizing Conditions (D. Habel, E. Feike, C. Schroder, H. Schubert, A. Hosch, J.,Stelzer, J. Caro, C. Hess, and A. Knop-Gericke). Synthesis and Characterization of Cubic Silicon Carbide (O-Sic) and Trigonal Silicon Nitride (a-Si,N,) Nanowires (K. Saulig-Wenger, M. Bechelany, D. Cornu, S. Bernard, F. Chassagneux, P. Miele, and T. Epicier). High Energy Milling Behavior of Alpha Silicon Carbide (M. Aparecida Pinheiro dos Santos and C. Albano da.Costa Neto). Synthesis of Boron Nitride Nanotubes for Engineering Applications (J. Hurst, D. Hull, and D. Gorican). Comparison of Electromagnetic Shielding in GFR-Nano Composites (W.-K. Jung, S.-H. Ahn, and M.-S. Won). Densification Behavior of Zirconia Ceramics Sintered Using High-Frequency Microwaves (M. Wolff, G. Falk, R. Clasen, G. Link, S. Takayama, and M. Thumm). Manufacturing of Doped Glasses Using Reactive Electrophoretic Deposition (REPD) (D. Jung, J. Tabellion, and R. Clasen). Shaping of Bulk Glasses and Ceramics with Nanosized Particles (J. Tabellion and R. Clasen). Author Index.
£99.86
John Wiley & Sons Inc Ceramic Coatings CESP V27 Is3 39 Ceramic
Book SynopsisPart of the proceedings of the 30th International Conference on Advanced Ceramics and Composites, January 22-27, 2006, Cocoa Beach, Florida. Organized and sponsored by The American Ceramic Society and The American Ceramic Society's Engineering Ceramics Division in conjunction with the Nuclear and Environmental Technology Division.Table of ContentsPreface. Introduction. Advanced Thermal Barrier Coating Development and Testing. Relation of Thermal Conductivity with Process Induced Anisotropic Void Systems in EB-PVD PYSZ Thermal Barrier Coatings (A. Flores Renteria, B. Saruhan, and J. llavsky). Segmentation Cracks in Plasma Sprayed Thin Thermal Barrier Coatings (Hongbo Guo, Hideyuki Murakami, and Seiji Kuroda). Design of Alternative Multilayer Thick Thermal Barrier Coatings (H. Samadi and T. W. Coyle). Creep Behaviour of Plasma Sprayed Thermal Barrier Coatings (Reza Soltani, Thomas W. Coyle, and Javad Mostaghimi). Corrosion Rig Testing of Thermal Barrier Coating Systems (Robert VaOen, Doris Sebold, Gerhard Pracht, and Detlev Stover). Thermal Properties of Nanoporous YSZ Coatings Fabricated by EB-PVD (Byung-Koog Jang, Norio Yamaguchi, and Hideaki Matsubara). Oxidation Behavior and Main Causes for Accelerated Oxidation in Plasma Sprayed Thermal Barrier Coatings (Hideyuki Arikawa, Yoshitaka Kojima, Mitsutoshi Okada, Takayuki Yoshioka, and Tohru Hisamatsu). Crack Growth and Delamination of Air Plasma-Sprayed Y203-ZrO, 8 1 TBC After Formation of TGO Layer (Makoto Hasegawa, Yu-Fu Liu, and Yutaka Kagawa). Lanthanum-Lithium Hexaaluminate-A New Material for Thermal Barrier Coatings in Magnetoplumbite Structure-Material and Process Development (Gerhard Pracht, Robert VaOen and Detlev Stover). Modeling and Life Prediction of Thermal Barrier Coatings. Simulation of Stress Development and Crack Formation in APS-TBCS For Cyclic Oxidation Loading and Comparison with Experimental Observations (R. Herzog, P. Bednarz, E. Trunova, V. Shernet, R. W. Steinbrech, F. Schubert, and L. Singheiser). Numerical Simulation of Crack Growth Mechanisms Occurring Near the Bondcoat Surface in Air Plasma Sprayed Thermal Barrier Coatings (A. Casu, J.-L. Marques, R. VaOen, and D. Stover). Comparison of the Radiative Two-Flux and Diffusion Approximations (Charles M. Spuckler). Damage Prediction of Thermal Barrier Coating (Y. Ohtake). Environmental Barrier Coatings for Si-Based Ceramics. The Water-Vapour Hot Gas Corrosion Behavior of AI,03-Y,03 Materials, Y,SiO, and Y3Al,0,,-Coated Alumina in a Combustion Environment (Marco Fritsch and Hagen Klernm). Evaluation of Environmental Barrier Coatings for SiC/SiC Composites (H. Nakayama, K. Morishita, S. Ochiai, T. Sekigawa, K. Aoyarna, and A. lkawa). Life Limiting Properties of Uncoated and Environmental-Barrier Coated Silicon Nitride at Higher Temperature (Sung R. Choi, Dongrning Zhu, and Rarnakrishna T. Bhatt). Multilayer EBC for Silicon Nitride (C. A. Lewinsohn, Q. Zhao, and B. Nair). Non-Destructive Evaluation of Thermal and Environmental Barrier Coatings. Characterization of Cracks in Thermal Barrier Coatings Using Impedance Spectroscopy (Lifen Deng, Xiaofeng Zhao, and Ping Xiao). Nondestructive Evaluation Methods for High Temperature Ceramic Coatings (William A. Ellingson, Rachel Lipanovich, Stacie Hopson, and Robert Visher). Nondestructive Evaluation of Environmental Barrier Coatings in CFCC Combustor Liners (J. G. Sun, J. Benz, W. A. Ellingson, J. G. Kimmel, and J. R. Price). Ceramic Coatings for Spacecraft Applications. Charging of Ceramic Materials Due to Space-Based Radiation Environment (Jennifer L. Sample, Ashish Nedungadi, Jordan Wilkerson, Don King, David Drewry, Ken Potocki, and Doug Eng). Spacecraft Thermal Management via Control of Optical Properties in the Near Solar Environment (David Drewry, Don King, Jennifer Sample, Dale Clemons, Keith Caruso, Ken Potocki, Doug Eng, Doug Mehoke, Michael Mattix, Michael Thomas, and Denis Nagle). Multifunctional Coatings and Interfaces. Preparation of Carbon Fiber Reinforced Silicon Oxycarbide Composite by Polyphenylsilsesquioxane Impregnation and Their Fracture Behavior (Manabu Fukushima, Satoshi Kobayashi, and Hideki Kita). Interfacial Processing Via CVD For Nicalon Based Ceramic Matrix Composites (Christopher L. Hill, Justin W. Reutenauer, Kevin A. Arpin, Steven L. Suib, and Michael A. Kmetz). Coatings of Fe/FeAIN Thin Films (Yuandan Liu, R. E. Miller, Tao Zhang, Qiquan Feng, W. Votava, Dingqiang Li, L. N. Dunkleberger, X. W. Wang, R. Gray, T. Bibens, J. Helfer, K. Mooney, R. Nowak, P. Lubitz, and Yanwen Zhang). Polymeric and Ceramic-Like Coatings on the Basis of SiN(C) Precursors for Protection of Metals Against Corrosion and Oxidation (M. Gunthner, Y. Albrecht, and G. Motz). Effect of Temperature and Spin-Coating Cycles on Microstructure Evolution for Tb-Substituted SrCeO, Thin Membrane Films (Satyajit Shukla, Mohamed M. Elbaccouch, Sudipta Seal, and Ali T-Raissi). Development of Boridized Passivation Layer for Use in PEM Fuel Cells Bipolar Plates (K. Scott Weil, Jin Yong Kim, Gordon Xia, Jim Coleman, and Z. Gary Yang). Functionally Graded Materials. Carbon-Fiber-Reinforced Low Thermal Expansion Ceramic Matrix Composites (C. M. Chan and A. J. Ruys). Development of the Impeller-Dry-Blending Process for the Fabrication of Metal-Ceramic Functionally Graded Materials (D. T. Chavara and A. J. Ruys). Author Index.
£99.86
John Wiley & Sons Inc Solid Oxide CESP V 27 Is 4 40 Ceramic Engineering
Book SynopsisDue to its many potential benefits, including high electrical efficiency and low environmental emissions, solid oxide fuel cell (SOFC) technology is the subject of extensive research and development efforts by national laboratories, universities, and private industries.Table of ContentsPreface xi Introduction xiii Overview and Current Status Development of Two Types of Tubular SOFCs at TOT0 3Akira Kawakami, Satoshi Matsuoka, Naoki Watanabe, Takeshi Saito, Akira Ueno, Tatsumi Ishihara, Natsuko Sakai, and Harumi Yokokawa Cell and Stack Development Development of Solid Oxide Fuel Cell Stack Using Lanthanum Gallate-Based Oxide as an Electrolyte 17T. Yamada, N. Chitose, H. Etou, M. Yamada, K. Hosoi, N. Komada, T. Inagaki, F. Nishiwaki, K. Hashino, H. Yoshida, M. Kawano, S. Yamasaki, and T. lshihara Anode Supported LSCM-LSGM-LSM Solid Oxide Fuel Cell 27Alidad Mohammadi, Nigel M. Sammes, Jakub Pusz, and Alevtina L. Smirnova Characterization/Testing Influence of Anode Thickness on the Electrochemical Performance of Single Chamber Solid Oxide Fuel Cells 37B. E. Buergler, Y. Santschi, M. Felberbaum, and L. J. Gauckler Investigation of Performance Degradation of SOFC Using Chromium-Containing Alloy Interconnects 47D. R. Beeaff, A. Dinesen, and P. V. Hendriksen Degradation Mechanism of Metal Supported Atmospheric Plasma Sprayed Solid Oxide Fuel Cells 55D. Hathiramani, R. VaOen, J. Mertens, D. Sebold, V. A. C. Haanappel, and D. Stover Effect of Transition Metal Ions on the Conductivity and Stability of Stabilized Zirconia 67D. Lybye and M. Mogensen Thermophysical Properties of YSZ and Ni-YSZ as a Function of Temperature and Porosity 79M. Radovic, E. Lara-Curzio, R. M. Trejo, H. Wang, and W. D. Porter Physical Properties in the Bi2O3-Fe2O3S ystem Containing Y2O3 and CaO Dopants 87Hsin-Chai Huang, Yu-Chen Chang, and Tzer-Shin Sheu Electrical Properties of Ce0.8Gd0.2O1.9 Ceramics Prepared by an Aqueous Process 95Toshiaki Yamaguchi, Yasufumi Suzuki, Wataru Sakamoto, and Shin-ichi Hirano Structural Study and Conductivity of BaZr0.90Ga0.10O2.95 105lstaq Ahmed, Elisabet Ahlberg, Sten Eriksson, Christoper Knee, Maths Karlsson, Aleksandar Matic, and Lars Borjesson Hydrogen Flux in Terbium Doped Strontium Cerate Membrane 119Mohamed M. Elbaccouch and Ali T-Raissi A Mechanical-Electrochemical Theory of Defects in Ionic Solids 125Narasimhan Swaminathan and Jianmin Qu Electrodes Nanostructured Ceramic Suspensions for Electrodes and the Brazilian SOFC Network "Rede PaCOS" 139R. C. Cordeiro, G. S. Trindade, R. N. S. H. MagalhSies, G. C. Silva, P. R. Villalobos, M. C. R. S. Varela, and P. E. V. de Miranda Modeling of MlEC Cathodes: The Effect of Sheet Resistance 153David S. Mebane, Erik Koep, and Meilin Liu Cathode Thermal Delamination Study for a Planar Solid Oxide Fuel Cell with Functional Graded Properties: Experimental Investigation and Numerical Results 161Gang Ju, Kenneth Reifsnider, and Jeong-Ho Kim Electrochemical Characteristics of Ni/Gd-Doped Ceria and Ni/Sm-Doped Ceria Anodes for SOFC Using Dry Methane Fuel 175Caroline Levy, Shinichi Hasegawa, Shiko Nakamura, Manabu Ihara, and Keiji Yamahara Control of Microstructure of NiO-SDC Composite Particles for Development of High Performance SOFC Anodes 183Koichi Kawahara, Seiichi Suda, Seiji Takahashi, Mitsunobu Kawano, Hiroyuki Yoshida, and Toru lnagaki Electrochemical Characterization and Identification of Reaction Sites in Oxide Anodes 193T. Nakamura, K. Yashiro, A. Kairnai, T. Otake, K. Sato, G.J . Park, T. Kawada, and J. Mizusaki Interconnects and Protective Coatings Corrosion Performance of Ferritic Steel for SOFC Interconnect Applications 201M. Ziomek-Moroz, G. R. Holcomb, B. S. Covino, Jr., S. J. Bullard, P. D. Jablonski, and D. E. Alrnan High Temperature Corrosion Behavior of Oxidation Resistant Alloys Under SOFC Interconnect Dual Exposures 211Zhenguo Yang, Greg W. Coffey, Joseph P. Rice, Prabhakar Singh, Jeffry W. Stevenson, and Guan-Guang Xia Electro-Deposited Protective Coatings for Planar Solid Oxide Fuel Cell Interconnects 223Christopher Johnson, Chad Schaeffer, Heidi Barron, and Randall Gemmen Properties of (Mn,Co)3O4 Spinel Protection Layers for SOFC Interconnects 231Zhenguo Yang, Xiao-Hong Li, Gary D. Maupin, Prabhakar Singh, Steve P. Sirnner, Jeffry W. Stevenson, Guan-Guang Xia, and Xiaodong Zhou Fuel Cell Interconnecting Coatings Produced by Different Thermal Spray Techniques 241E. Garcia and T. W. Coyle Surface Modification of Alloys for Improved Oxidation Resistance in SOFC Applications 253David E. Alman, Paul D. Jablonski, and Steven C. Kung Seals Composite Seal Development and Evaluation 265Matthew M. Seabaugh, Kathy Sabolsky, Gene B. Arkenberg, and Jerry L. Jayjohn Investigation of SOFC-Gaskets Containing Compressive Mica Layers Under Dual Atmosphere Conditions 273F. Wiener, M. Brarn, H.-P. Buchkrerner, and D. Sebold Performance of Self-Healing Seals for Solid Oxide Fuel Cells (SOFC) 287Raj N. Singh and Shailendra S. Parihar Properties of Glass-Ceramic for Solid Oxide Fuel Cells 297S. T. Reis, R. K. Brow, T. Zhang, and P. Jasinski Mechanical Behavior of Solid Oxide Fuel Cell (SOFC) Seal Glass-Boron Nitride Nanotubes Composite 305Sung R. Choi, Narottam P. Bansal, Janet B. Hurst, and Anita Garg Mechanical Behaviour of Glassy Composite Seals for IT-SOFC Application 315K. A. Nielsen, M. Solvang, S. B. L. Nielsen, and D. Beeaff Mechanical Property Characterizations and Performance Modeling of SOFC Seals 325Brian J. Koeppel, John S. Vetrano, Ba Nghiep Nguyen, Xin Sun, and Moe A. Khaleel Mechanical Properties Fracture Test of Thin Sheet Electrolytes 339Jurgen Malzbender, Rolf W. Steinbrech, and Lorenz Singheiser Failure Modes of Thin Supported Membranes 347P. V. Hendriksen, J. R. Hprgsberg, A. M. Kjeldsen, B. F. Sorensena, and H. G. Pedersen Comparison of Mechanical Properties of NiO/YSZ by Different Methods 361Dustin R. Beeaff, S. Ramousse, and Peter V. Hendriksen Fracture Toughness and Slow Crack Growth Behavior of Ni-YSZ and YSZ as a Function of Porosity and Temperature 373M. Radovic, E. Lara-Curzio, and G. Nelson Effect of Thermal Cycling and Thermal Aging on the Mechanical Properties of, and Residual Stresses in, Ni-YSZ/YSZ Bi-Layers 383E. Lara-Curzio, M. Radovic, R. M. Trejo, C. Cofer, T. R. Watkins, and K. L. More Three-Dimensional Numerical Simulation Tools for Fracture Analysis in Planar Solid Oxide Fuel Cells (SOFCs) 393Janine Johnson and Jianmin Qu Modeling Electrochemistry and On-Cell Reformation Modeling for Solid Oxide Fuel Cell Stacks 409K. P. Recknagle, D. T. Jarboe, K. I. Johnson, V. Korolev, M. A. Khaleel, and P. Singh Modeling of HeaVMass Transport and Electrochemistry of a Solid Oxide Fuel Cell 419Yan Ji, J. N. Chung, and Kun Yuan Author Index 435
£99.86
John Wiley & Sons Inc Ceramics in Nuclear and Alternative Energy
Book SynopsisThis volume focuses on recent developments and advances of ceramics and ceramic matrix composites for use in fission and fusion reactors, nuclear fuels and alternative energy applications. With the continued increasing demands for energy, nuclear energy has experienced a renewed interest. Recent developments associated with advanced fuel cycles have resulted in new research efforts on nuclear fuel materials. The effects of radiation on the properties of ceramics and ceramic matrix composites are also addressed.Table of ContentsPreface. Introduction. Irradiation Effects in Ceramics. (GenlV) Next Generation Nuclear Power and Requirements for Standards, Codes and Data Bases for Ceramic Matrix Composites (Michael G. Jenkins, Edgar Lara-Curzio, and William E. Windes). Determination of Promising Inert Matrix Fuel Compounds (C. R. Stanek, J. A. Valdez, K. E. Sickafus, K. J. McClellan, and R. W. Grimes). Densification Mechanism and Microstructural Evolution of Sic Matrix in NlTE Process (Kazuya Shimoda, Joon-Soon Park, Tatsuya Hinoki, and Akira Kohyama). Optimization of Sintering Parameters for Nitride Transmutation Fuels (John T. Dunwoody, Christopher R. Stanek, Kenneth J. McClellan, Stewart L. Voit, Thomas Hartmann, Kirk Wheeler, Manuel Parra, and Pedro D. Peralta). Ceramics in Non-Thermal Plasma Discharges for Hydrogen Generation (R. Vintila, G. Mendoza-Suarez, J. A. Kozinski, and R. A. L. Drew). Piezoelectric Ceramic Fiber Composites for Energy Harvesting to Power Electronic Components (Richard Cass, Farhad Mohammadi, and Stephen Leschin). Design Factor Using a SiC/SiC Composites for Core Component of Gas Cooled Fast Reactor. I: Hoop Stress (Jae-Kwang Lee and Masayuki Naganuma). Characterizations of Ti,SiC, as Candidate for the Structural Materials of High Temperature Reactors (Fabienne Audubert, Guillaume Abrivard, and Christophe Tallaron). Influence of Specimen Type and Loading Configuration on the Fracture Strength of Sic Layer in Coated Particle Fuel (T. S. Byun, S. G. Hong, L. L. Snead, and Y. Katoh). Investigation of Aluminides as Potential Matrix Materials for Inert Matrix Nuclear Fuels (Darrin D. Byler, Kenneth J. McClellan, James A. Valdez, Pedro D. Peralta, and Kirk Wheeler). Fluidised Bed Chemical Vapour Deposition of Pyrolytic Carbon (E. Lopez Honorato, P. Xiao, G. Marsh, and T. Abram). Ceramics for Advanced Nuclear and Alternative Energy Applications. Strength Testing of Monolithic and Duplex Silicon Carbide Cylinders in Support of Use as Nuclear Fuel Cladding (Denwood F. Ross, Jr. and William R. Hendrich). Subcritical Crack Growth in Hi-Nicalon Type-S Fiber CVI-SiC/SiC Composites (Charles H. Henager, Jr.). Electrical Conductivity of Proton Conductive Ceramics Under Reactor Irradiation (Tatsuo Shikama, Bun Tsuchiya, Shinji Nagata, and Kentaro Toh). The Effects of Irradiation-Induced Swelling of Constituents on Mechanical Properties of Advanced SiCISiC Composites (Kazumi Ozawa, Takashi Nozawa, and Tatsuya Hinoki, and Akira Kohyama). Behaviors of Radioluminescence of Optical Ceramics for Nuclear Applications (T. Shikama, S. Nagata, K. Toh, 6. Tsuchiya, and A. lnouye). Author Index.
£99.86
John Wiley & Sons Inc Bioceramics CESP V27 Is6 43 Ceramic Engineering
Book SynopsisThe use of ceramics in biological environments and biomedical applications is of increasing importance, as is the understanding of how biology works with minerals to develop strong materials.Table of ContentsPreface. Introduction. In Vitro Evaluation. Initial In Vitro Interaction of Human Osteoblasts with Nanostructured Hydroxyapatite (NHA) (Xingyuan Guo, Julie Gough, Ping Xiao, Jing Liu, and Zhijian Shen). Osteoblast Response to Zinc-Doped Sintered p-Tricalcium Phosphate (Sahil Jalota, Sarit 8. Bhaduri, and A. Cuneyt Tas). Determination of the Spatial Resolution of Micro-Focus X-Ray CT System with a Standard Specimen (Mineo Mizuno, Yasutoshi Mizuta, Takeharu). Kato, and Yasushi lkeda Processing of Biomaterials. Hydroxyapatite Hybridized with Metal Oxides for Biomedical Applications (Akiyoshi Osaka, Eiji Fujii, Koji Kawabata, Hideyuki Yoshirnatsu, Satoshi Hayakawa, Kanji Tsuru, Christian Bonhornrne, and Florence Babonneau). Preparation of Self-setting Cement-Based Micro- and Macroporous Granules of Carbonated Apatitic Calcium Phosphate (A. Cuneyt Tas). A Self-setting, Monetite (CaHPO,) Cement for Skeletal Repair (Tarang R. Desai, Sarit B. Bhaduri, and A. Cuneyt Tas). Chemically Bonded Ceramics Based on Ca-Aluminates as Biomaterials (L. Herrnansson and H. Engqvist). A Theoretical and Mathematical Basis Towards Dispersing Nanoparticles and Biological Agents in a Non Polar Solvent for Fabricating Porous Materials (Navin J. Manjooran and Gary R. Pickrell). Preparation of Hydroxyapatite and Calcium Phosphate Bioceramic Materials from the Aqueous Solution at Room Temperature (Jia-Hui Liao, Yu-Chen Chang, and Tzer-Shin Sheu). Hydroxyapatite Coatings Produced by Plasma Spraying of Organic Based Solution Precursor (E. Garcia, Z. B. Zhang, T. W. Coyle, L. Gan, and R. Pilliar). Visible-Light Photocatalytic Fibers for Inactivation of Pseudomonas Aeruginosa (P. G. Wu, R. C. Xie, J. Irnlay, and J. K. Shang). Precipitation Mechanisms of Hydroxyapatite Powder in the Different Aqueous Solutions (Yu-Chen Chang and Tzer-Shin Sheu). Conversion of Bioactive Silicate (45S5), Borate, and Borosilicate Glasses to Hydroxyapatite in Dilute Phosphate Solution (Wenhai Huang, Moharned N. Raharnan, and Delbert E. Day). Dental Ceramics. Variable Frequency Microwave (VFM) Processing: A New Tool to Crystallize Lithium Disilicate Glass (Morsi Mahmoud, Diane Folz, Carlos Suchicital, David Clark, and Zak Fathi). Author Index.
£99.86
John Wiley & Sons Inc Advances in Ceramic Armor II Volume 27 Issue 7
Book SynopsisThese proceedings contain current research from industry, academia and government organizations, working on opaque and transparent ceramic armor. Papers on novel materials concepts for both vehicle and body armors are included, as well as papers that explore the relationship between computational modeling and property testing. These papers were presented at the Proceedings of the 30th International Conference on Advanced Ceramics and Composites, January 22-27, 2006, Cocoa Beach, Florida. Organized and sponsored by The American Ceramic Society and The American Ceramic Society''s Engineering Ceramics Division in conjunction with the Nuclear and Environmental Technology Division.Table of ContentsPreface. Introduction. A Review of Computational Ceramic Armor Modeling (Charles E. Anderson. Jr.). Silicon Carbide. Biomorphic SiSiC-Materials for Lightweight Armour (Bernhard Heidenreich, Michaela Gahr, Elmar StraDburger, and Ekkehard Lutz). Evaluation of Sic Armor Tile Using Ultrasonic Techniques (J. Scott Steckenrider, William A. Ellingson, Rachel Lipanovich, Jeffrey Wheeler, and Chris Deemer). Spherical Indentation of Sic (A. A. Wereszczak and K. E. Johanns). Damage Modes Correlated to the Dynamic Response of Sic-N (H. Luo and W. Chen). Grain Boundary Chemistry of Sic-Based Armor (Edgardo Pabit, Kerry Siebein, Darryl P. Butt, Helge Heinrich, Darin Ray, Sarbjit Kaur, R. Marc Flinders, and Raymond A. Cutler). Effect of Microstructure and Mechanical Properties on the Ballistic Performance of Sic-Based Ceramics (Darin Ray, Marc Flinders, Angela Anderson, Raymond A. Cutler, James Campbell, and Jane W. Adams). Addition of Excess Carbon to Sic to Study its Effect on Silicon Carbide (Sic) Armor (Chris Ziccardi and Richard Haber). Glass and Transparent Ceramics. Analysis of Time-Resolved Penetration of Long Rods into Glass Targets-l I (Charles E. Anderson, Jr., I. Sidney Chocron, and Carl E. Weiss). Response and Characterization of Confined Borosilicate Glass: Intact and Damaged (Kathryn A. Dannemann, Arthur E. Nicholls, Charles E. Anderson, Jr., Sidney Chocron, and James D. Walker). Constitutive Model for Damaged Borosilicate Glass (Sidney Chocron, James D. Walker, Arthur E. Nicholls, Charles E. Anderson, and Kathryn A. Dannemann). Reaction Sintered LiAlON (Raymond A. Cutler and R. Marc Flinders). Large Area EFGTM Sapphire for Transparent Armor (Christopher D. Jones, Jeffrey B. Rioux, John W. Locher, Herbert E. Bates, Steven A. Zanella, Vincent Pluen, and Mattias Mandelartz). Other Opaque Ceramics. Relationship of Microstructure and Hardness for A120, Armor Materials (Memduh Volkan Demirbas and Richard A. Haber). Root Causes of the Performance of Boron Carbide Under Stress (Giovanni Fanchini, Dale E. Niesz, Richard A. Haber, James W. McCauley, and Manish Chhowalla). Analysis of Texture in Controlled Shear Processed Boron Carbide (D. Maiorano, R. Haber, and G. Fanchini). Damage and Testing. Progress in the Nondestructive Analysis of Impact Damage in Ti62 Armor Ceramics (Joseph M. Wells). Elastic Property Determination of WC Spheres and Estimation of Compressive Loads and lmpact Velocities That Initiate Their Yielding and Cracking (A. A. Wereszczak). On the Role of Impact Damage in Armor Ceramic Performance (Joseph M. Wells). The Indentation Size Effect (ISE) for Knoop Hardness in Five Ceramic Materials (Trevor Wilantewicz, W. Roger Cannon, and George Quinn). Influence of Microstructure on the Indentation-Induced Damage in Silicon Carbide (Jeffrey J. Swab, Andrew A. Wereszczak, Justin Pritchett, and Kurt Johanns). Author Index.
£90.86
John Wiley & Sons Inc High Temperature Corrosion
Book SynopsisReviews the science and engineering of high-temperature corrosion and provides guidelines for selecting the best materials for an array of system processes High-temperature corrosion (HTC) is a widespread problem in an array of industries, including power generation, aerospace, automotive, and mineral and chemical processing, to name a few. This book provides engineers, physicists, and chemists with a balanced presentation of all relevant basic science and engineering aspects of high-temperature corrosion. It covers most HTC types, including oxidation, sulfidation, nitridation, molten salts, fuel-ash corrosion, H2S/H2 corrosion, molten fluoride/HF corrosion, and carburization. It also provides corrosion data essential for making the appropriate choices of candidate materials for high-temperature service in process conditions. A form of corrosion that does not require the presence of liquids, high-temperature corrosion occurs due to the inteTable of ContentsPreface xi Acknowledgments xvii 1 Introduction 1 1.1 Definition of High Temperature Corrosion 1 1.2 Historical Development 1 1.3 High Temperature Corrosion Phenomena 3 1.4 High Temperature Materials 3 1.5 Corrosive Environments 27 1.6 Films and Scales 31 1.7 Academic Impact of High Temperature Corrosion 33 1.8 Industrial Impact of High Temperature Corrosion 38 1.9 Questions 46 References 46 Further Reading 47 2 Metallurgical Structure and Metals 48 2.1 Imperfections in an Essentially Perfect Structure 48 2.2 Solidification 56 2.3 Alloys 62 2.4 Iron and Steel 72 2.5 Deformation and Recrystallization 79 2.6 Fracture and Fatigue 91 2.7 Questions and Problems 97 References 98 Further Reading 99 3 High Temperature Equilibria 100 3.1 Introduction 100 3.2 Thermochemical Analysis 100 3.3 Electrochemical Analysis 119 References 128 Further Reading 129 4 Lattice Defects in Metal Compounds 130 4.1 Introduction 130 4.2 Defect Reactions 133 4.3 Defect Equilibria 135 4.4 Equilibrium Constants 141 4.5 Questions 144 References 144 Further Reading 145 5 Diffusion in Solid-State Systems 146 5.1 Introduction 146 5.2 General Theory of Diffusion 146 5.3 Diffusion Coefficients 150 5.4 Matano–Boltzmann Analysis 153 5.5 Kirkendall Effect 154 5.6 Darken Analysis 155 5.7 Factors Influencing Diffusion 156 5.8 Impurity Diffusion in Metals 158 5.9 Grain Boundary Diffusion in Metals 158 5.10 Diffusion in Solid Oxides 160 5.11 Morphology of Reaction Products 163 5.12 Measurement of Diffusion Parameters 164 5.13 Questions and Problems 168 References 168 Further Reading 169 6 High Temperature Electrochemistry 171 6.1 Introduction 171 6.2 Electrochemical Nature of Molten Salt Corrosion 171 6.3 The Single Potential of an Electrode 172 6.4 Equilibrium Diagrams 173 6.5 The Tafel Relationship 173 6.6 Corrosion Potential–pO2−Relationship 175 6.7 Electrochemical Polarization and Monitoring 177 6.8 Electrochemical Nature of Metal Oxidation 179 6.9 Usefulness of Electrochemical Cells 181 6.10 Current–Potential Measurements on Solid Electrodes 182 6.11 Simple Concepts of Oxide Semiconductors 183 6.12 Conduction Processes in Ionic Oxides 186 6.13 Common Solid-State Electrochemical Situations 190 References 194 Further Reading 195 7 Oxidation 196 7.1 Introduction 196 7.2 Thermodynamic Considerations 197 7.3 Kinetic Considerations 199 7.4 Defect Structures 201 7.5 Compact Scale Growth 208 7.6 Multilayered Scale Growth 212 7.7 Oxidation Resistance 214 7.8 Oxidation of Engineering Materials 224 7.9 Conclusions 228 7.10 Questions 229 References 229 Further Reading 231 8 Sulfidation 233 8.1 Introduction 233 8.2 The Process of Sulfidation 233 8.3 Sulfidation Kinetics 235 8.4 Sulfidation of Selected Materials 236 8.5 Defect Structures of Metal Sulfides 240 8.6 Questions 243 References 243 Further Reading 244 9 Carburization and Metal Dusting 245 9.1 Introduction 245 9.2 Carburization 245 9.3 Alloy Resistance to Carburization 251 9.4 Metal Dusting Problem 255 9.5 Metal Dusting Mechanisms 256 9.6 Alloy Resistance to Metal Dusting 260 References 262 Further Reading 263 10 Nitridation 264 10.1 Introduction 264 10.2 Nitridation Mechanisms 264 10.3 Nitridation in Industrial Media 265 10.4 Questions and Problems 273 References 274 Further Reading 275 11 Halogenation 276 11.1 Introduction 276 11.2 Metal–Halogen Reactions 277 11.3 Alloy–Halogen Reactions 279 11.4 Laboratory Studies 280 11.5 Conclusions 282 11.6 Questions 282 References 282 Further Reading 283 12 Corrosion by Hydrogen and Water Vapor 284 12.1 Introduction 284 12.2 Corrosion by Hydrogen 284 12.3 Corrosion by Water Vapor 290 12.4 Conclusions 293 References 294 Further Reading 295 13 Corrosion in Molten Salts 296 13.1 Introduction 296 13.2 Corrosion Process 296 13.3 Thermodynamic Diagrams 298 13.4 Corrosion Rate Measurements 299 13.5 Test Methods 299 13.6 Fluorides 303 13.7 Chlorides 304 13.8 Nitrates/nitrites 305 13.9 Hydroxides 309 13.10 Carbonates 309 13.11 Vanadates 312 13.12 Sulfates 314 13.13 Prevention of Molten Salt Corrosion 321 13.14 Summary 321 References 322 Further Reading 324 14 Corrosion in Molten Metals 325 14.1 Introduction 325 14.2 Corrosive Processes 326 14.3 Industrial Liquid Metals 332 14.4 Conclusions 338 References 339 Further Reading 339 15 Hot Corrosion 340 15.1 Introduction 340 15.2 Engine Description and Materials 340 15.3 Early Studies 341 15.4 Mechanisms of Hot Corrosion 349 15.5 Hot Corrosion of Gas Turbine Alloys 351 15.6 Methods of Evaluating Hot Corrosion 354 15.7 Prevention of Corrosion 356 15.8 Conclusions 358 15.9 Questions 358 References 359 Further Reading 360 16 Fireside Corrosion 361 16.1 Introduction 361 16.2 Coal-Fired Boilers 362 16.3 Coal-ash Corrosion 371 16.4 Oil-Fired Boilers 373 16.5 Corrosion in Waste Incinerators 379 16.6 Plant Experience with Fireside Corrosion 380 16.7 Conclusions 388 References 389 Further Reading 389 17 Testing and Evaluation 391 17.1 Introduction 391 17.2 Testing Equipment and Monitoring 392 17.3 Optical Microscopy 394 17.4 Thermogravimetry 395 17.5 Spectroscopy 398 17.6 Diffraction Techniques 402 17.7 Electron Microscopy 409 17.8 Electron Spectroscopy and Ion Scattering 416 17.9 Surface Microscopy 424 17.10 Optical Spectroscopy 428 17.11 Nondestructive Inspection Techniques 439 17.12 Traditional Electrochemical Methods 445 17.13 Nontraditional Electrochemical Methods 453 17.14 Combined Electrochemical Methods 459 References 472 Further Reading 475 18 Protective Coatings 477 18.1 Introduction 477 18.2 Coating Systems 477 18.3 Coating Processes 480 18.4 Coating Degradation 496 18.5 Summary and Future Trends 499 18.6 Questions 500 References 500 Further Reading 501 19 Examples of Engineering Importance 502 19.1 Introduction 502 19.2 Molten Carbonate Fuel Cells 504 19.3 Solid Oxide Fuel Cells 516 19.4 Direct Carbon Fuel Cells 524 19.5 Nuclear Power Plants 531 References 546 Further Reading 549 20 Case Studies 551 20.1 Making Stainless Steels 551 20.2 Corrosion Protection of Turbine Blades 551 20.3 Oxidation of Silicides for VLSI Applications 556 20.4 Naphthenic Acid Corrosion in Petrochemical Plants 560 20.5 Oxidation of Ceramic Matrix Composites 562 20.6 Shell Corrosion of Rotary Cement Kilns 563 20.7 Corrosion of Steels in a Linear 𝛼Olefin Plant 564 References 565 Further Reading 565 Appendix A 566 List of Acronyms 591 Glossary of Selected Terms Used in High Temperature Corrosion 596 Author Index 615 Subject Index 629
£146.66
John Wiley & Sons Inc Biodegradable Polymer Blends and Composites from
Book SynopsisProvides a comprehensive and current resource for understanding and working with biodegradable polymers Guides the scientist in designing new materials by exploring the relationship between structure and properties for each category of blends/composites discussed.Trade Review"Combining fundamental science with real-life applications and potential markets, this book is ideal for material and polymer scientists as well as students who are interested in studying and bringing these new environmentally friendly and bio based materials to market." (Macromolecular Chemistry and Physics, April 2009)Table of ContentsPART I: NATURAL POLYMER BLENDS AND COMPOSITES. 1. Polymers from Renewable Resources (L. Yu and L. Chen). 1.1 Introduction. 1.2 Natural Polymers. 1.3 Synthetic Polymers from Natural Monomers. 1.4 Polymers from Microbial Fermentation. 1.5 Summary. 2. Starch - Cellulose Blends (I. S. Arvanitoyannis and A. Kassaveti). 2.1 Introduction. 2.2 Starch and Starch Derivatives. 2.3 Cellulose and Cellulose Derivatives. 2.4 Starch-Cellulose Blends. 2.5 Applications. 3. Starch Sodium Caseinate Blends (I. S. Arvanitoyannis and P. Tserkezou). 3.1 Introduction. 3.2 Starch and Starch Derivatives. 3.3 Sodium Caseinate Derivatives. 3.4 Starch- Sodium Caseinate Blends. 3.5 Applications. 3.6 Comparison between Sodium Caseinate and other Edible films. 4. Novel Plastics and Foams from Starch and Polyurethanes (Y. Lu and L. Tighzert). 4.1 Introduction. 4.2 Starch-Filled Polyurethane Elastomers and Plastics. 4.3 Starch-Filled Polyurethane Foams. 4.4 Starch Grafted with Polyurethanes. 4.5 Thermoplastic Starch/Polyurethane Blends. 4.6 Concluding Remarks. 5. Chitosan Properties and application (N. Soares). 5.1 Sources. 5.1 Structures. 5.2 Application in Food Industry. 5.3 Antimicrobial Property. 5.4 Others Properties. 5.5 Chitosan derivatives . 6. Blends and Composites Based on Cellulose/Natural Polymers (Y. Wang and L. Zhang). 6.1 Introduction. 6.2 Cellulose: Structure and Solvents. 6.3 Cellulose/Natural Polymers Blends. 6.4 Cellulose Derivatives/Natural Polymers Blends. 6.5 Promising Application of Cellulose Blends. PART II: ALIPHATIC POLYESTER BLENDS. 7. Stereocomplex between Enantiomeric Poly(lactide)s (H. Tsuji and Y. Ikada). 7.1 Introduction. 7.2 Stereocomplex formation. 7.3 Methods for inducing stereocomplexation. 7.4 Physical Properties. 7.5 Biodegradation. 7.6 Applications. 8. Polyhydroxyalkanoates Blends and Composities (G. Q. Chen and Tsinghua). 8.1 Introduction. 8.2 PHA Blended with Starch or Cellulose. 8.3 PHA Blended with PLA. 8.4 PHA Blended with PCL. 8.5 Blending of Different PHA. 8.6 PHA Blending with other Polymers. 8.7 PHA Composites. PART III: HYDROPHOBIC AND HYDROPHILIC POLYMERIC BLENDS. 9. Starch-Poly(hydroxyalkanoate) Composites and Blends (R. Shogren). 9.1 Summary of starch, PHA structure and properties. 9.2 Why blend starch with PHA's?. 9.3 Problems with starch-PHA blends. 9.4 Granular starch-PHA composites. 9.5 Gelatinized starch-PHA blends. 9.6 Thermoplastic Starch/PHA Laminates and Foams. 9.7 Biodegradability, Recycling and Sustainability. 9.8 Applications and Production. 9.9 Future Research Needs and Directions. 10. Biodegradable Blends Based on Microbial Poly(3-hydroxybutyrate) and Natural Chitosan (C. Chen and L. Dong). 10.1 Introduction. 10.2 Preparation and Properties. 10.3 Conclusion. PART IV: NATURAL FIBER-REINFORCED COMPOSITES. 11. Starch-Cellulose Fibres Composites (A. V’quez and V. Alvarez). 11.1 Introduction. 11.2 Starch Polymer. 11.3 Starch-Cellulose Fibre Composites. 11.4 Starch Based Blends as Polymer Matrix . 11.5 Starch Based Blend/Natural Fibre Composites . 11.6 Conclusion. 12. PLA/Cellulosic Fiber Composites (M. Shibata). 12.1 Introduction. 12.2 PLA/Abaca Composites. 12.3 PLA/Wood Flour Composites. 12.4 PLA/Lyocell Composites. 12.5 Conclusions. 13. Biocomposites of Natural Fibres and Poly(3-hydroxybutyrate) and Copolymers: Improved Mechanical Properties Through Compatibilization at the Interface (S. Wong and R. A. Shanks). 13.1 Traditional Composites and Novel Biodegradable Composites. 13.2 Natural Fibres. 13.3 Mechanical Properties of Natural Fibres. 13.4 Biodegradable Polymers. 13.5 Major Problems Associated with High Strength Composites. 13.6 Summary. 14. Starch-Fiber Composites (M. A. Hanna and Y. Xu). 14.1 Introduction. 14.2 Starch-Based Biopolymers. 14.3 Natural Fibers. 14.4 Starch-Natural Fiber Blends. 14.5 Summary. PART V: BIODEGRADABLE NANOCOMPOSITES. 15. Starch based nanocomposites using layered minerals (H.R. Fischer and J.J. de Vlieger). 15.1 Introduction. 15.2 Starch-montmorillonite nano-composites. 15.3 Starch based nanocomposites using different layered minerals. 15.4 Biodegradable starch-polyester nanocomposite materials. 15.5 Discussion and Conclusions. 16. Polylactide Based Nanocomposites (S. S. Ray and J. Ramontja). 16.1 Introduction. 16.2 PLA Nanocomposites based on Clay. 16.3 PLA Nanocomposites based on Carbon Nanotubes. 16.4 PLA Nanocomposites based on other Nanofillers. 16.5 Properties of PLA Nanocomposites. 16.6 Biodegradability. 16.7 Melt Rheology. 16.8 Foam Processing . 16.9 Applications Possibilities and Future Prospect. 17. Advances in Natural Rubber/Montmorillonite Nanocomposites (D. Jia, L. Liu, X. Wang, B. Guo, and Y. Luo). 17.1 Introduction. 17.2 Materials and Process. 17.3 Characterization. 17.4 Results and Discussions. 17.5 Summary. PART VI: MULTILAYER DESIGNED MATERIALS. 18. Multilayer Coextrusion of Starch/Biopolyester (L. Av’ous). 18.1 Introduction. 18.2 Materials and Process. 18.3 Characterization. 18.4 Results and Discussions. 18.5 Conclusion.
£130.45
