Cellular biology (cytology) Books

581 products


  • Humana Lineage Tracing

    Out of stock

    Book SynopsisBayesian Phylogenetic Lineage Reconstruction with Loss of Heterozygosity Mutations Derived from Single-cell RNA Sequencing.- Tracking somatic mutations for lineage reconstruction.- Multicolor cell lineage tracing using MAGIC Markers strategies.- Single cell lineage tracing and clonal state-fate analysis.- Lineage recording in human brain organoids with iTracer.- Clonal tracking in the mouse brain with single-cell RNA-seq.- Lineage tracing by light-sheet microscopy and computational reconstruction.- Reconstructing progenitor state hierarchy and dynamics using lineage barcoding data.- Tracking cell phylogenies in the human brain with somatic mosaic mutations.- Paired single-cell transcriptome and DNA barcode detection in zebrafish using ScarTrace.- LINNAEUS - Simultaneous single-cell lineage tracing and cell type identification.- In Vivo Clonal Analysis Using MADM with Spatio-temporal Specificity.- CARLIN: a mouse line for simultaneous readout of lineage histories and gene expression.

    Out of stock

    £189.99

  • Humana Intracellular Lipid Transport

    Out of stock

    Book SynopsisSelective Labeling of Phosphatidylcholine to Track Their Translocation Between Organelles in Living Cells.- Measurement of ORP10-Mediated Lipid Countertransport at ER-Endosome Membrane Contact Sites Via a Chemically-Induced Dimerization Strategy.- Analysis of Phosphatidylinositol Transfer at ER-PM Contact Sites in Receptor-Stimulated Live Cells.- Use of the D4H Probe to Track Sterols in Yeast.- Maistero-2, a Novel Probe for Sterols: Application for Visualizing Cellular Cholesterol.- Using GRAM Domain-Based Biosensors to Monitor Accessible Cholesterol Distribution in Live Cells.- Monitoring Accessible Cholesterol Levels in Immune Cells.- Methods for Visualizing and Quantifying Cholesterol Distribution in Mammalian Cells Using Filipin and D4 Probes.- HEK293 Cell-Based Assay to Measure the Lipid Scrambling Activity of TMEM16 Family Members.- Measuring Phospholipid Flippase Activity by NBD-Lipid Uptake in Living Yeast Cells.- Advanced Method for the In Vivo Measurements of Lysophospholi

    Out of stock

    £189.99

  • Humana Spermatology

    Out of stock

    Book SynopsisSpermatology: Current Methods to Study Sperm Classical Variables.- Evolutionary Aspects of Sperm Physiology and Its Assessment.- Assessment of Boar Semen Morphology and Morphometry.- Semen Extraction and Analysis in Domestic Animals.- Semen Extraction and Management in Wild Animals: TUMASG Technique.- Semen Extraction and Analysis in Avian Species.- Boar Semen Assessment for the Production of Artificial Insemination Doses.- Semen Evaluation in the Production of Bovine Artificial Insemination Doses.- Sperm Vitrification in Horse and Donkey.- Cryopreservation of Dog Semen.- Rabbit Sperm Cryopreservation.- Cryopreservation of Small Ruminant Sperm and Detection of Sperm Cryocapacitation.- Sperm Cyropreservation in Boars.- Cryopreservation of Horse Sperm.- New Delivery Systems on Sperm Quality Improvement.- Assessment of Sperm Motility with the Use of Computer-Aided Sperm Analysis (CASA).- Bioinformatics on Sperm Subpopulations using Computer Assisted Sperm Analysis (CASA).- Sperm Select

    Out of stock

    £274.22

  • Humana TCell Activation

    Out of stock

    Book SynopsisImaging protocol for super-resolution microscopy in fixed T cells.- Visualization and quantification of NFAT1 translocation in T cells.- Deep Learning-Based Image Restoration and Super-Resolution for Fluorescence Microscopy: Overview and Resources.- Analysing Point Accumulation in Nanoscale Topography (PAINT) data to decipher T cell receptor cluster signalling.- Measuring NAADP-evoked Ca2+ release in permeabilized T cells.- An improved two-dimensional HPLC method for endogenous 2'-deoxy-ADPR and 2'-deoxy-NAD.- Analysis of Store-Operated Ca2+ Entry in primary T cells.- Monitoring Dynamic of cAMP Signaling in Primary Murine CD4+ T Cells via Live-Cell Imaging.- Using specific reporter mice to assess CD4+ T cell transdifferentiation.- Generation of antigen-specific CD4+ primary rat T cell lines.- Induction and assessment of activation in rat effector CD4+ memory Th cells.- Imaging BiTE-mediated activation of primary human CD8+ T cells.- Flow cytometric analysis of mouse brain CD8+ T cel

    Out of stock

    £189.99

  • Humana The Surfaceome

    Out of stock

    Book SynopsisIntroduction: Methods for Studying the Plasma Membrane and the Surfaceome.- Optimized Biotinylated Peptide Detection Method for Characterizing the Cell Surface Proteome.- Proximity Labeling of Cell Surface Proteins via Cell Surface Remodeling.- BioID-Based Proximity Mapping of Transmembrane Proteins in Human Airway Cell Models.- Aminoox

    Out of stock

    £189.99

  • Humana Advanced Cell and Molecular Techniques

    Out of stock

    Book SynopsisCell Culture Techniques.- Solutions Preparation.- Standard Operating Procedure (SOP) for Maintaining Sterility in the Laminar Flow Hood During Cell Culture Procedures.- Protocol for Maintenance, Isolation, and Primary Culture of Ehrlich Tumor Cells.- Stem Cell Cultivation and Maintenance.- Protocol for Isolation of Stem Cells from Rabbit Adipose Tissue.- Protocol for Isolation of Lung Fibroblasts from Mouse Tissue.- Protocol for Isolation of Mice Fat Stem Cells.- Protocol for Isolation of Mouse Adipose-Derived Stem Cells (ADSCs).- Protocol for Isolation of Bone Marrow Stem Cells.- Extraction of Mesenchymal Stem Cells (MSCs) from Human Liposuction Fat.- Human Bone Marrow Extraction Protocol.- Mesenchymal Stem Cells (MSCs) Differentiation Protocols.- cDNA Synthesis and Quantitative PCR (qPCR) for Gene Expression Analysis.- Preparation and Optimization of Reagents for Genetic Analysis and Infectious Disease Diagnosis.- DNA and RNA Extraction from Plasma Using Magnetized Silica.- RNA Extraction Using Trizol (6-Well Plate Method).- Agarose Gel Electrophoresis for RNA Integrity Assessment.- DNA Purification Using the Wizard Plus SV Minipreps DNA Purification System (Promega).- Detection of Reactive Oxygen Species (ROS) in Embryos.- Determination of Protein Concentration: Sedmak and Grossberg Method.- Cell Sorting of Fluorescent Zebrafish Cells.- Cell Disaggregation for Flow Cytometry Analysis of Fluorescent Zebrafish Cells.- RNA Extraction from Zebrafish Embryos for RT-qPCR.- Extraction of Genomic DNA.- RNA Extraction from HEK293.- Agarose Gel Preparation for RNA and DNA Electrophoresis.- Zebrafish Genotyping by Fin Clipping.- In Situ Hybridization of Zebrafish Embryos.- Concepts and Practices in Flow Cytometry.- In Situ Apoptosis Assay.- Flow Cytometry Protocols for Assessing Membrane Integrity, Cell Cycle, and Apoptosis in Treated Cells.- Leukocyte Reading Protocol on the Flow Cytometer.- Flow Cytometry Protocol for Mouse Sperm Cells (BD Accuri C6+).- Extraction of Yolk Proteins from 24 HPF Zebrafish Embryos.- PFA Fixation for Zebrafish Embryos.- Thioflavin T (ThT) Fluorescence Measurement.- Alcian Blue Staining Protocol.- Zebrafish Embryo Staining with Nicotinamide Adenine (NA).- Western Blot on Zebrafish Embryos.- In Vitro Micronucleus Assay in Binucleated CHO-K1 Cells.- In Vitro Assessment of Genotoxicity Using the Comet Assay in CHO-K1 Cells.- Treatment and Cell Collection for Chromosomal Aberration Test.- Electrophoretic Mobility Shift Assay (EMSA): Non-Radioactive, Band Shift, Gel Shift, or Gel Retardation.- MTT Assay Protocol.- Spectropolarimeter (Jasco-1500) Operation Protocol.- Immunoprecipitation Protocol (Tuning).- qPCR EvaGreen Hot FIREPol Mix.- Synthesis of RNA-Digoxigenin Probe.- Thermal Difference Spectra (TDS).- Generation of Competent Bacteria.- Retro Transcription via STEM LOOP.- In Vitro Transcription with the mMessage mMachine SP6 Transcription Kit.- Transfection in HEK293 Cells.- HeLa Transfections with Lipofectamine 3000.- Chemical Competent Cell Transformation.

    Out of stock

    £151.99

  • Springer-Verlag New York Inc. Mammalian Oocyte Development

    Out of stock

    Out of stock

    £151.99

  • Humana Spermatogenesis

    Out of stock

    Book SynopsisProfiling Histone Modifications in Differentiating Mouse Spermatogonia with CUT&Tag.- Quantitative CUT&Tag for Epigenomic Profiling of Mouse Germ Cells.- Spatial Transcriptomic Analyses of Spermatogenesis.- Identification of RNA Targets of Highly Conserved RNA Binding Proteins Essential for Animal Sperm Development.- Generation of Organotypic Testicular Organoids from Rat and Pig Primary Cells in Microwell Culture.- Inhibiting Aldehyde Dehydrogenase Function Using WIN 18,446 to Synchronize Spermatogenesis.- Individualization of Testicular Cells for Single-Cell Subcellular Immunocytochemistry and Cell Culture Applications.- Isolation of Pig or Rodent Sertoli Cells for Use in Transplantation.- Density Gradient-Based Separation of Testicular Cell Types Using a STA-PUT Apparatus.- Antibody Labeling of Mouse Spermatocyte Chromosome Spreads to Study Meiosis.- Transillumination-Assisted Microdissection for Precise Staging of Seminiferous Tubules in Mice.- Immunofluorescence Staining of the Manchette and Developing Sperm Flagella in Mouse.- Methods of Mammalian In Vitro Sperm Capacitation to Study Sperm Physiology.- Analysis of Motion Characteristics and Plasma Membrane Intactness (Viability) in Sperm from Domestic Animals.- Methods to Determine Oxidative Stress in Spermatozoa.- Methods to Evaluate DNA Damage in Spermatozoa.- Cre Deleter Mouse Lines for Conditional Knockout of Genes in Testis Cell Types.

    Out of stock

    £170.99

  • Humana SUMO

    Out of stock

    Book SynopsisThe SUMO Pathway.- SUMO Antibody Validation.- Native and Endogenous SUMO Site Identification Using Mass Spectrometry (NESSI-MS).- A Fluorometric Assay to Compare SUMO Isoforms Preferences in the SENP/ULP Family.- Production and Purification of SUMO-UBC9 and SUMO-RANGAP1CTD.- Synthesizing Defined Ubiquitin-Modified SUMO Dimers.- In Vitro SUMOylation Assays with a DNA-Sensitive Multi-Subunit E3 Ligase.- Cell-Based Assays to Study SUMOylation in Drosophila.- SUMO-Activated Target Traps (SATTs) for the Identification of Specific SUMOylated Proteins for an E3 Ligase of Interest.- Synthesis and Application of SUMO-Based Probes for SUMO Protease Profiling.- Measurement of Substrate SUMOylation in Real Time by Fluorescence Spectroscopy.- Production and Purification of Recombinant SUMOylation Enzymes and SUMO Proteins.- Non-Hydrolysable ADP-Ribosylated SUMO2 via Copper(I) Catalyzed Azide Alkyne Cycloaddition.- A Vivo-Morpholino-Based Approach to Block Paralog-Specific SUMOylation.- Bimolecular Fluorescence Complementation Assay to Evaluate the Interaction between SUMO and Its Target Proteins in Cells.

    Out of stock

    £142.49

  • Lulu.com GeneRationing

    15 in stock

    15 in stock

    £25.00

  • Springer-Verlag New York Inc. Bioelectromagnetics Current Concepts

    15 in stock

    Book SynopsisProceedings of the NATO Advanced Research Workshop on The Mechanisms of the Biological Effect on Extra High Power Pulses (EHPP), Yerevan, Armenia 3 - 5 March 2005Table of ContentsPreface.Acknowledgements. Chapter I. Mechanisms of EMF interactions with biological systems. Thermal vs. nonthermal Mechanisms of Interactions between Electromagnetic Fields and Biological Systems; M. Markov.- The Mechanisms Paradox; K. Foster.- Cell Aqua Medium as a Primary Target for the Effecy of Electronmagnetic Fields; S.Ayrapetyan.- The Effect of ELF EMF-Pretreated Distillated Water on Barley seed Hydration and Germination Potential; A. Amyan and S. Ayrapetyan.- Intracellular Calcium Signaling Basic Mechanisms and Possible Alterations; P. Kostyuk and E. Lukyanetz.-Suppression of Synaptic Transmission in Hippocampus by extremely-high-power Microwave Pulses Synchronized with Neuronal Excitation; J. Doyle et al.-The in vitro Assessment of Potential Genotoxicity of High Power Microwave Pulses; N. Chemeris at al.- Unconventional Approach to Biological Effects of EMF; B. Sernelius.- The Effect of Iron Ions and weak static or low Frequency(50 HZ) Magnetic Fields on Lymphocytes: free Radical Processes; J. Jajte and M. Zmyslony.-Collagen as a Target for Electromagnetic Fields. Effects of 910-mhz on Rat Brain; M. Tzaphlidou and E. Fotiou.-Animal Studies on the Effects of ELF and Static EMF; N.Seyhan et al.- Chapter II. EMF Therapy. Interactions Between Electromagnetic Fields and Immune System: Possible Mechanism for Pain Control; M.Markov et al.- Electromagnetic Field Therapy: A Role for Water?;C. Hazlewood et al.- Physiological Mechanisms Underlying Millimeter Wave Therapy; M. Ziskin.-Anti-Inflammatory Effects of low-intensity Millimeter Wave Radiation; A.Gapeyev et al.- Study of the Secretion of Melatonin and Stress Hormones in Operators from Broadcasting and TV-Stations Exposed to Radiofrequency (RF) Electromagnetic Radiation (EMR) ; M. Israel et al.-The Combining Effect of the ferrocene Compounds with electro magnetic Field ; A. F. Badawi and A.A.Hafiz.-Chapter III. EMF Dosimetry. High-Frequency Device for the Measurement of the Specific Absorbed Rate by the Biotissues of High Intensity; R. Simonyan et al.-Physical Aspects of Pulsed Microwave Absorption in Tissue; P.Šístek.- Exposure Metrics of Magnetic Fields related to Power Lines and electric Applicances T. Saito et al.-Chapter IV. Epidemiology and policy Science, Uncertainty and Policy for Power and Mobile Frequency EMF; L. Kheifets.-Risk Evaluation of Potential Environmental Hazards from low energy electromagnetic Field Exposure using sensitive In Vitro Methods; F. Adlkofer.-Can the Radiation from Cellular Phones have important Effects on the Forces between Biological-Tissue-Components?; B.E.Sernelius.-Exposure to non-ionizing radiation of personnel in Physiotherapy; M.Israel and P. Tschobanoff.- Chapter V. Posters. Changes of the Magnitude of Arteriolar Vasomotion during and after ELF-EMF Exposure in Vivo L.Traikov et al.-The Effects of SMF, EHPP and Hydrogen Peroxide on the Development of Yeasts; N. Baghdasaryan and S.Ayrapetyan.- Inhibition of Melatonin Synthesis in Human Peripheral Blood Lymphocytes by EMF: A Mechanism of Interaction? ; R.Coghill and R. Baghurst.- A Study of Melatonin in Plant Tissues and its Dietary and Health Implications; R. Baghurst and R.Coghill.-Effect of High Dilution Quinones on 02 uptake by peripheral Blood Lymphocytes: A Polarographic Study; C. Conners and R. Coghill.-Internal originators of Functions Fluctuation in Multi-Celled Organisms; R.D. Grygoryan and P.N. Lissov.-List of speakers. List of participants. Official Photograph. Index

    15 in stock

    £170.99

  • Springer New York Branching Processes in Biology

    15 in stock

    Trade Review“This book is the result … of a fruitful and long collaboration between a mathematician and a cell biologist. Capturing the best of both worlds, the book provides not only the biology and mathematical background for this topic, but also offers numerous examples which render it accessible to (post-graduate) students and researchers … . this book can be treated as an excellent textbook for a wide audience varying from students to lecturers.” (Irina Ioana Mohorianu, zbMATH 1312.92004, 2015)"This book treats the theory of several important types of branching processes and demonstrates their usefulness by many interesting and important applications. … Mathematical theory and biological applications are nicely interwoven. This text will be useful both to mathematicians (including graduate students) interested in relevant applications of stochastic processes in biology, as well as to mathematically oriented biologists working on the above mentioned topics." (R. Bürger, Monatshefte für Mathematik, Vol. 143 (1), 2004)"This is a significant book on applications of branching processes in biology, and it is highly recommended for those readers who are interested in the application and development of stochastic models, particularly those with interests in cellular and molecular biology." (Charles J. Mode, Siam Review, Vol. 45 (2), 2003)"This is a book written jointly by a mathematician and a cell biologist, who have collaborated on research in branching processes for more than a decade. In their own words, their monograph is intended for ‘mathematicians and statisticians who have had an introduction to stochastic processes but have forgotten much of their college biology, and for biologists who wish to collaborate with mathematicians and statisticians.’ They have largely succeeded in achieving their goal. The book can be strongly recommended to all students of branching processes; all libraries should have a copy." —ZENTRALBLATT MATH Table of ContentsMotivating Examples and Other Preliminaries.- Biological Background.- The Galton-Watson Process.- The Age-Dependent Process: Markov Case.- The Bellman-Harris Process.- Multitype Processes.- Branching Processes with Infinitely Many Types.- Genealogies of Branching Processes and their Applications.- References.

    15 in stock

    £64.99

  • Createspace Independent Publishing Platform The Blood and Its Third Element

    15 in stock

    15 in stock

    £14.79

  • Taylor & Francis Inc Functional Lipidomics

    Out of stock

    Book SynopsisLipids play an essential role in cell signaling and subcellular structure. Systematic analysis of the total lipid structure of a cell or organism, the lipodome, can reveal novel avenues of therapeutic intervention and diagnosis. This analysis is best modeled after the lessons learned from proteomics. With contributions from pioneering researchers from the US, Europe, Canada, Japan, and China, Functional Lipidomics introduces lipidomics, explores the current state of the field, and provides a comprehensive background for future groundbreaking work in this burgeoning field.The first book dedicated to the topic, Functional Lipidomics first defines and introduces the field before delving deeply into the methods, processes, analyses, and research aspects. The book uncovers the biosynthesis, metabolism, and function of fatty acids, acylglyerols, glycerophospholipids, sphingolipids, terpenes, and lipids that complex with proteins. Taking both academic and industrial perspectives, the contributors elaborate upon cutting-edge approaches to lipid analysis, diagnostic approaches using lipid and lipid-binding protein patterns, and the therapeutic significance of targeting proteins involved with the lipid signaling pathway. Functional Lipidomics elucidates state-of-the-art strategies and techniques that enable us to understand biochemical patterns related to disease states, develop new targets for drug design, and identify important markers of a developmental stage, pathological condition, or disease treatment.Table of ContentsThe LIPID MAPS Approach to Lipidomics. LC/MS Methodology in Lipid Analysis and Structural Characterization of Novel Lipid Species. Functional Plasticity of Lipid Mediators: The Example of Endocannabinoids. Eicosanoid Lipidomics. Functional Lipidomics: Lysophosphatidic Acid as a Target for Molecular Diagnosis and Therapy of Ovarian Cancer. Analysis of Lysophospholipids in Human Body Fluids: Comparison of the Lysophospholipid Content in Malignant vs. Nonmalignant Diseases. Functional Lipidomics: Lessons and Examples from the Sphingolipids. Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Analysis of Sphingolipids. Methods of Probing Phosphoinositides–Protein Interactions. Fishing for Pharmaceutically Relevant phosphoinositide-Binding Proteins Using Chemical Proteomics. Phosphoinositide Profiling in Complex Lipid Mixtures. Multiplexed Lipid Arrays of Antiimmunoglobulin M–Induced Changes in the Glycerophospholipid Composition of WEHI-231 Cells. Specific Lipid Alterations in Alzheimer’s Disease and Diabetes: Shotgun Global Cellular Lipidome Analyses by Electrospray Ionization Mass Spectrometry Using Intrasource Separation. High-Throughput Lipid Profiling to Identify and Characterize Genes Involved in Lipid Metabolism, Signaling, and Stress Response.

    Out of stock

    £999.99

  • Humana Press Inc. Parkinson’s Disease and Movement Disorders: Diagnosis and Treatment Guidelines for the Practicing Physician

    15 in stock

    Book SynopsisThe field of movement disorders is relatively broad, encompassing disorders of increased movement, such as tremors, dystonia, and tics, to disorders characterized by a paucity of movement, such as Parkinson's disease. Our understanding of the pathogenic mechanisms and our treatment options are expanding at a rapid pace. This expansion ranges from the medical and surgical advances in treating Parkinson's disease to the flood of genetic abnormalities that have now been found to cause various movement disorders. Although many patients are seen by the movement disorders specialist in neurology clinics around the country, most of these patients receive their followup care from a primary care physician or "general" neurologist who must be versed in the character­ istics and treatment plans of this diverse group of disorders. The major goal of Parkinson's Disease and Movement Disorders: Diagnosis and Treatment Guidelines for the Practicing Physician is to distill this immense amount of information and to educate the practitioner about the many facets of the movement disorders field. We believe that this book fills a large void, since most texts on movement disorders are more detailed and geared toward the specialist. We have asked the chapter authors to emphasize the clinical characteristics of each disorder, discuss the differential diagnosis and the diagnostic testing, and then outline the various treatment options, as if they were teaching during a preceptorship in their clinic.Trade Review". . .this book demystifies, enlightens, and educates. . .an outstanding accomplishment. . .the style is uniform and the text reader-friendly. . .punctuated with useful tables, [and] the clinical descriptions and practical approach to patient mamagement are what make this an exceptional text. General neurologists, movement disorders fellows, and internists will all find this book and excellent source."-Neurology "There are 35 well-written chapters aimed at the practicing neurologist, 12 of which cover the management of early and late Parkinson's disease. Considerable attention is given to the selection of drug treatment. The remaining chapters cover a variety of other movement disorders including tremor, myoclonus, tics, Wilson's disease, dystonia, and tardive dyskinesia. . ."-Doody's Health Science Book Review Journal ...this book has comprehensive coverage of Parkinson's disease and other movement disorders. The book is most useful for family practitioners, neurologists, gerontologists and residents. An appropriate book for institutional libraries as well." - Doody's Health Science Book Review JournalTable of ContentsPart A. Basic Diagnostic Principles. Approach to the Patient With a Movement Disorder: Basic Principles of Neurologic Diagnosis, J. Eric Ahlskog, phd, md. Motor Speech Disorders: Clues to Neurologic Diagnosis, Joseph R. Duffy, phd. Part B. Parkinson's Disease. What Is Parkinson's Disease? Neuropathology, Neurochemistry, and Pathophysiology, Howard Hurtig, md. Clinical Features of Parkinson's Disease, Richard B. Dewey, Jr., md. Epidemiology and Genetics of Parkinson's Disease, Demetrius M. (Jim) Maraganore, md. Parkinson's Disease: Etiologic Considerations, Peter A. LeWitt, md. Medication Strategies for Slowing the Progression of Parkinson's Disease, J. Eric Ahlskog, phd, md. Initial Symptomatic Treatment of Parkinson's Disease, J. Eric Ahlskog, phd, md. Advancing Parkinson's Disease and Treatment of Motor Complications, Ryan J. Uitti, md. Sleep and Parkinson's Disease, Cynthia L. Comella, md, absm. Autonomic Complications of Parkinson's Disease, Bradley C. Hiner, md. Treatment of Cognitive Disorders and Depression Associated With Parkinson's Disease, Erwin B. Montgomery, Jr., md. Surgical Treatment of Parkinson's Disease, Kathleen M. Shannon, md. Adjunctive Therapies in Parkinson's Disease: Diet, Physical Therapy, and Networking, Padraig E. O'Suilleabhain, mb, and Susan M. Murphy, md. Part C. Parkinsonism but Not Parkinson's Disease (Other Akinetic-Rigid Syndromes). Introduction. Secondary Causes of Parkinsonism, Eric S. Molho, md, and Stewart A. Factor, do. Progressive Supranuclear Palsy, Mark Stacy, md. Multiple System Atrophy, James H. Bower, md. Familial Adult-Onset Spinocerebellar Degenerations, James H. Bower, md. Corticobasal Degeneration, Bradley F. Boeve, md. Parkinsonism in Primary Degenerative Dementia, Richard J. Caselli, md. Part D. Movement Disorders Characterized by Excessive Movement (Hyperkinetic). Introduction. Tremor Disorders: Overview, Joseph Y. Matsumoto, md. Essential Tremor: Diagnosis and Treatment, Jean Pintar Hubble, md. Dystonia, Daniel Tarsy, md. Hemifacial Spasm, Mark F. Lew, md. Huntington's Disease and Other Choreas, John N. Caviness, md. Tardive Dyskinesias, Kapil D. Sethi, md, frcp. Myoclonus, John N. Caviness, md. Spasms and Stiff-man Syndrome, C. Michel Harper, Jr., md. Gilles de la Tourette's Syndrome and Tic Disorders, Kathleen A. Kujawa, md, phd, and Christopher G. Goetz, md. Restless Legs Syndrome, Virgilio Gerald H. Evidente, md, and Charles H. Adler, md, phd. Botulinum Toxin Treatment of Movement Disorders, Charles H. Adler, md, phd. Part E. Other Movement Disorders. Wilson's Disease, Katrina A. Gwinn-Hardy, md. Gait Disorders: Recognition of Classic Types, Frank A. Rubino, md. Post-traumatic Movement Disorders, Sotirios A. Parashos, md, phd. Psychogenic Movement Disorders: Theoretical and Clinical Considerations, David S. Glosser, ScD, and Matthew B. Stern, md. Appendix. Index.

    15 in stock

    £151.99

  • Humana Press Inc. Stem Cells & Regenerative Medicine: From Molecular Embryology to Tissue Engineering

    15 in stock

    Book SynopsisDefined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.Trade ReviewFrom the reviews:“The Introduction by the two editors is clearly telling the aim of such a bible, to cover from the basic aspects of molecular embriology dealing with the stemness cellular capacity … till the new challenging opportunities of tissue engineering. I think the price of the book (€ 170) is worthy enough for what the reader will get. … a book with all the figures in colour, this is a great help while looking at cytology, histology or entangled graphs!” (Carlo Alberto Redi, European Journal of Histochemistry, Vol. 55, 2011)Table of ContentsSection 1: Stem Cell Biology.- Introduction to Stem Cells & Regenerative Medicine.- Embryonic Stem Cells: Discovery, Development, and Current Trends.- Bmi1 in self-renewal and homeostasis of pancreas.- Cancer Stem Cells in Solid Tumors.- Adipose-derived stem cells and skeletal muscle repair.- Regeneration of sensory cells of adult mammalian inner ear.- Stem Cells and Their Use in Skeletal Tissue Repair.- Section 2: Epigenetic and microRNA Regulation in Stem Cells.- Epigenetic identity in cancer stem cells.- Function of MicroRNA-145 in Human Embryonic Stem Cell Pluripotency.- Mesenchymal Stem Cells for Liver Regeneration.- Section 3: Stem Cells for Therapeutic Applications.- The Role of Time-Lapse Microscopy in Stem Cell Research and Therapy.- Therapeutic applications of mesenchymal stem/multipotent stromal cells.- Gastrointestinal stem cells.- Lung epithelial stem cells.- Placental Derived Stem Cells, Potential Clinical Applications.- Bone Marrow Cell Therapy for Acute Myocardial Infarction: A Clinical Trial Review.- Stem cell Transplantation to the Heart.- Adult Neural Progenitor Cells and Cell Replacement Therapy for Huntington’s Disease.- Migration of Transplanted Neural Stem Cells in Experimental Models of Neurodegenerative Diseases.- Prospects for neural stem cell therapy of Alzheimer’s disease.- Section 4: Nuclear Reprogramming and induced Pluripotent Stem Cells.- Nuclear transfer ES cells as a new tool for basic biology.- Pluripotent stem cells in reproductive medicine: Formation of the human germ line in vitro.- Prospects for Induced Pluripotent Stem Cell Therapy for Diabetes.- Keratinocyte induced pluripotent stem cells: from hair to where?.- Generation and Characterization of Induced Pluripotent Stem Cells from Pig.- Induced pluripotent stem cells, on the road toward clinical applications.- Direct reprogramming of human neural stem cells by the single transcription factor Oct 4.- Section 5: Tissue Engineering.- Stem cells and biomaterials: the tissue engineering approach.- Micro-technology for stem cell culture.- Using Lab-on-A-Chip Technologies for Stem cell Biology.- The Development of Small Molecules and Growth Supplements to Control the Differentiation of Stem Cells and the Formation of Neural Tissues.- Long-term propagation of neural stem cells: Focus on 3D culture systems and mitogenic factors.- Section 6: Regenerative Medicine.- Stem Cells and Regenerative Medicine in Urology.- Muscle derived stem cells: a model for stem cell therapy in regenerative medicine.- Regenerative strategies for cardiac disease.- Collecting, Processing, Banking and Use of Cord Blood Stem Cells for Regenerative Medicine.

    15 in stock

    £189.99

  • Humana Press Inc. Molecular Mechanisms of Neurotransmitter Release

    15 in stock

    Book SynopsisNeurons in the nervous system organize into complex networks and their functions are precisely controlled. The most important means for neurons to communicate with each other is transmission through chemical synapses, where the release of neurotransmitters by the presynaptic nerve terminal of one neuron influences the function of a second neuron. Since the discovery of chemical neurotransmission by Otto Loewi in the 1920s, great progress has been made in our understanding of mol- ular mechanisms of neurotransmitter release. The last decade has seen an explosion of knowledge in this field. The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage of essentially all major mole- lar mechanisms of neurotransmitter release. The contributors have made great efforts to write concisely but with sufficient background information, and to use figures/diagrams to present clearly key concepts or experiments. It is hoped that this book may serve as a learning tool for neuroscience students, a solid reference for neuroscientists, and a source of knowledge for people who have a general interest in neuroscience. I was fortunate to be able to gather contributions from a group of outstanding scientists. I thank them for their efforts. In particular, I want to thank Dr. Erik Jorgensen who offered valuable suggestions about the book in addition to contrib- ing an excellent chapter. I thank US National Science Foundation and National Institute of Health for their supports.Trade ReviewFrom the reviews: “Molecular Mechanisms of Neurotransmitter Release edited by Zhao Wen Wang provides the reader with a comprehensive overview of the complex interactions occurring in pre synaptic neurons involved with chemical communication. … High quality illustrations a large number of which are in full color, support the information in the text … . This book is recommended for the researcher and student of neuroscience … . Neurology residents undergoing specialty training in neuromuscular disease will find this book to be an invaluable resource.” (Joseph Vito Russo, Medical Science Books, April, 2010)Table of Contents1. The Architecture of the Presynaptic Release Site R. Grace Zhai 2. Multiple modes of fusion and retrieval at the calyx of Held synapse Liming He, Benjamin McNeil, and Ling-Gang Wu 3. Roles of SNARE proteins in synaptic vesicle fusion Mark T. Palfreyman and Erik M. Jorgensen 4. Roles and sources of calcium in synaptic exocytosis Zhao-Wen Wang, Bojun Chen, Qian Ge 5. Regulation of presynaptic calcium channels Allen W. Chan and Elise F. Stanley 6. Synaptotagmin: transducing Ca2+-binding to vesicle fusion Carin Loewen and Noreen Reist 7. Functional interactions between the SNARE regulators UNC-13, tomosyn and UNC-18 Robby M. Weimer and Janet E. Richmond 8. Roles of the ELKS/CAST family and SAD kinase in Neurotransmitter Release Toshihisa Ohtsuka and Yoshimi Takai 9. The role of potassium channels in the regulation of neurotransmitter release. Laurence O. Trussell and Michael T. Roberts 10. Modulation of neurotransmitter release and presynaptic plasticity by protein phosphorylation Zu-Hang Sheng 11. Synaptic Vesicle Endocytosis Liesbet Smitz and Patrik Verstreken 12. Lipids and secretory vesicle exocytosis Shona L. Osborne and Frederic A. Meunier 13. Neurotransmitter reuptake and synaptic vesicle refilling Richard J. Reimer*, Kimberly A. Zaia, and Hiroaki Tani 14. Regulation of neurotransmitter release by presynaptic receptors Matthew Frerking, and Joyce Wondolowski 15. Trans-synaptic regulation of presynaptic release machinery in central synapses by cell adhesion molecules Kensuke Futai and Yasunori Hayashi 16. Differential regulation of small clear vesicles and large dense-core vesicles Tao Xu and Pingyong Xu

    15 in stock

    £142.49

  • Callisto Reference Encyclopedia of Cell Biology

    15 in stock

    Book Synopsis

    15 in stock

    £94.99

  • Callisto Reference Cell Physiology

    Out of stock

    Out of stock

    £99.68

  • Callisto Reference Plant Cell Biology: Structures and Functions

    Out of stock

    Book Synopsis

    Out of stock

    £101.70

  • Callisto Reference Textbook of Cell Biology

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    Out of stock

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