Biology, life sciences Books
Hodder Education OCR ASA Level Year 1 Biology A Workbook Exchange
Book SynopsisExam Board: OCR Level: A-Level Subject: Biology First Teaching: September 2015 First Exam: Summer 2016Our Student Workbooks build students'' understanding, developing the confidence and exam skills they need, whilst providing ready prepared lesson solutions.- Reinforce and apply topic understanding as classwork or extension tasks, or with revision- Prepare students to meet the demands of the new specification by practising exam technique- Create opportunities for independent learning and self-assessment with answers online- Supplement key resources such as textbooks - Time-saving and economical lesson solutions for both specialist and non-specialist teachers
£10.89
Hodder Education CCEA A2 Unit 1 Biology Student Guide Physiology
Book SynopsisExam Board: CCEALevel: A-levelSubject: BiologyFirst Teaching: September 2016First Exam: June 2018Reinforce students'' understanding throughout their course; clear topic summaries with sample questions and answers will improve exam technique to achieve higher gradesWritten by examiners and teachers, Student Guides: Help students identify what they need to know with a concise summary of the topics examined in the AS and A-level specification Consolidate understanding with exam tips and knowledge check questions Provide opportunities to improve exam technique with sample graded answers to exam-style questions Develop independent learning and research skills Provide the content for generating individual revision notes
£14.97
Hodder Education Edexcel Alevel Biology Student Guide Practical
Book SynopsisExam Board: EdexcelLevel: AS/A-levelSubject: BiologyFirst Teaching: September 2015First Exam: June 2016Ensure your students get to grips with the core practicals and develop the skills needed to succeed with an in-depth assessment-driven approach that builds and reinforces understanding; clear summaries of practical work with sample questions and answers help to improve exam technique in order to achieve higher grades.Written by experienced teacher Martin Rowland, this Student Guide for practical Biology:- Help students easily identify what they need to know with a concise summary of required practical work examined in the A-level specifications.- Consolidate understanding of practical work, methodology, mathematical and other skills out of the laboratory with exam tips and knowledge check questions, with answers in the back of the book.- Provide plenty of opportunities for students to improve exam tec
£15.48
Edinburgh University Press Deleuze and Evolutionary Theory
Book Synopsis9 essays focus on the significance of Deleuze and Guattari's engagements with evolutionary theory across the full range of their work, from the interpretation of Darwin in 'Difference and Repetition', to the symbiotic alliances of wasp and orchid in 'A Thousand Plateaus'.
£94.50
Edinburgh University Press Modernist Life Histories
Book SynopsisHow do literary forms relate to scientific models? When scientific paradigms shift, do the literary forms adapt? These are the questions motivating 'Modernist Life Histories'.
£90.25
Taylor & Francis Inc Nanotoxicology
Book SynopsisSince the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines.Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer proTable of ContentsImpacts of Nanotechnology on Biomedicine. Introduction to Biomedical Nanotechnology. Impact of Bionanointeractions of Engineered Nanoparticles for Nanomedicine. Rational Approach for the Safe Design of Nanomaterials. Characterization of Manufactured Nanomaterials, Dispersion, and Exposure for Toxicological Testing. Exposure. Workplace Inhalation Exposure to Engineered Nanomaterials: Detection, Measurement, and Assessment. Nanotechnology in Consumer Products: Addressing Potential Health and Safety Implications for Consumers. Modeling. Quantitative Nanostructure–Activity Relationships: From Unstructured Data to Predictive Models for Designing Nanomaterials with Controlled Properties. Pharmacokinetics and Biodistribution of Nanomaterials. Methodologies and Techniques. Advanced Methodologies and Techniques for Assessing Nanomaterial Toxicity: From Manufacturing to Nanomedicine Screening. Detection Methods for the In Vivo Biodistribution of Iron Oxide and Silica Nanoparticles: Effects of Size, Surface Chemistry, and Shape. Quantitative Single-Cell Approaches to Assessing Nanotoxicity in Nanomedicine Systems. Imaging Techniques for Nanoparticles in Skin. Hazards. Safety Implications of Nanomaterial Exposure to Skin. Interspecies Comparisons of Pulmonary Responses to Fine and/or Nanoscale Particulates: Relevance for Humans of Particle-Overload Responses in the Rat Model. Current In Vitro Models for Nanomaterial Testing in Pulmonary Systems. Nanoparticles and the Immune System. Carbon Nanotubes and Cardiovascular Disease. Single- and Multiwalled Carbon Nanotubes Toxicity and Potential Applications in Neuroregeneration. Current In Vitro Models for Nanomaterial Testing: The Reproductive System. Current In Vitro Models for Nanomaterial Testing: Genotoxicity Issues. Cell-Based Targeting of Anticancer Nanomaterials to Tumors. Silver Nanoparticles in Biomedical Applications. Cytotoxicity of Conjugated and Unconjugated Semiconductor and Metal Nanoparticles. Risk Assessment. Issues Related to Risk Assessment of Nanomaterials.Risk Assessment of Engineered Nanomaterials: State of the Art and Roadmap for Future Research. Index.
£171.00
Taylor & Francis Inc Liver Metabolism and Fatty Liver Disease
Book SynopsisNonalcoholic fatty liver disease is one of the most common liver diseases worldwide affecting patients from all ages, races, and ethnic backgrounds. It comprises a spectrum of hepatic pathology ranging from simple steatosis, in which there is an increase of fat accumulation in hepatocytes, to nonalcoholic steatohepatitis and cirrhosis. The significant prevalence of this diseasebetween 15 and 45 percent of the general populationmeans that it contributes to an increased burden of ill health both today and in the future.Liver Metabolism and Fatty Liver Disease addresses the current understanding of the development of nonalcoholic fatty liver disease as well as the clinical aspects of the disease by examining the current knowledge surrounding metabolism in the liver. The book discusses various topics including the involvement of oxidative stress, metabolic effects, and inflammation as well as the effect of nutrition on the development and progression of the disease.Table of ContentsIntroduction to Fatty Liver Disease and Consequences. Fatty Liver Disease and Consequences. Nutrition Role in Liver Protection and Damage.
£147.25
Taylor & Francis Inc Integrated Molecular Evolution
Book SynopsisEvolutionary biology has increasingly relied upon tools developed in molecular biology that allow for the structure and function of macromolecules to be used as data for exploring the patterns and processes of evolutionary change. Integrated Molecular Evolution, Second Edition is a textbook intended to expansively and comprehensive review evolutionary studies now routinely using molecular data. This new edition has been thoroughly updated and expanded, and provides a basic summary of evolutionary biology as well as a review of current phylogenetics and phylogenomics.Reflecting a burgeoning pedagogical landscape, this new edition includes nearly double the number of chapters, including a new section on molecular and bioinformatic methods. Dedicated chapters were added on: Evolution of the genetic code Mendelian genetics and population genetics Natural selection Horizontal gene transfers Animal development and plant development Trade ReviewRogers (molecular biology and evolution, Bowling Green State Univ.) has created an engaging, readable, accessible introduction to the field of molecular evolution. The book is organized in sections that follow a logical progression. A brief discussion of life and the basic features of evolutionary theory is followed by sections on basic macromolecules and cellular processes, Mendelian and population genetics, gene families, means of gene transfer, the developmental processes in multicellular organisms, and methods of molecular analysis and omics. The work ends with chapters devoted to the genomes of various organisms and agents, from viruses through humans. In each chapter, the discussion is tied to how the topic affects or is affected by the process of evolution. Each chapter ends with a summary of key points and contains a list of additional sources. The illustrations are effective and enhance the text. The book will be most useful to readers with a basic knowledge of molecular biology and development, as the background topics are covered in an appropriately succinct fashion. --M. S. Kainz, Ripon College Summing Up: Highly recommended. Upper-division undergraduates through faculty. CHOICE Table of ContentsLIFE AND EVOLUTION. Definitions of Life. Earth and Evolution. BIOMOLECULES. DNA, RNA, and Proteins. The Central Dogma and Beyond. Ribosomes and Ribosomal RNA. Structure of the Genetic Code. DNA Replication. DNA Segregation. GENETICS. Mendelian and Non-Mendelian Characters. Population Genetics. Alleles through Time. Changes to DNA. Infectious Changes to DNA: Viruses, Plasmids, Transposons, and Introns. MULTICELLULARITY. Multigene Families. Horizontal Gene Transfer. Development: Part I—Cooperation Among Cells. Development: Part II—Plants. Cancer. MOLECULAR BIOLOGY AND BIOINFORMATIC METHODS. Extraction and Quantification of Biological Molecules. Recombinant DNA and Characterization of Biological Molecules. Sequencing and Alignment Methods. OMICS: Part I. OMICS: Part II. Species Concepts and Phylogenetics. Phylogenetic Networks and Reticulate Evolution. Phylogenomics and Comparative Genomics. GENOMES. RNA Viruses. DNA Viruses. Bacteria and Archaea. Mutualists and Pathogens. Endosymbionts and Organelles. Protein Trafficking. Eukaryotic Genomes. Human Genome.
£120.00
Taylor & Francis Inc Biosimilar Clinical Development Scientific
Book SynopsisBiosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in clinical development, this book discusses various potential drug development strategies, the design and analysis of pharmacokinetics (PK) studies, and the design and analysis of efficacy studies.Trade Review"Thus, the book Biosimilar Clinical Development contains five chapters discussing general issues involving biosimilars. The remaining six chapters present statistical methods, many of which are new, and their applications in bioequivalence and biosimilarity studies; they are really research papers. . . It will appeal to readers interested in biosimilars and especially in their statistical assessments."~Laszlo Endrenyi, University of Toronto “The book is edited by a team of renowned experts from both statistics and biosimilar clinical development. It contains 11 chapters, covering not only statistical issues but also pre-clinical and clinical development issues not regularly discussed on this kind of book, as well as references to regulatory considerations of upmost importance for statisticians working in the strongly regulated environment of clinical development . . . I strongly recommend the reading of this book. In my opinion, the book should be a must-have reading for professionals who work regularly with biosimilars and want to have an overview of state-of-the art methods for 'hot-topics' in the analysis and planning of clinical trials for this purpose.”~David ManteigasTable of ContentsBiosimilars for Drug Development. Regulatory Requirements on Biosimilars. System Biology in the Context of Biosimilars. Clinical Considerations on Biosimilars. Large Molecules Complete Molecular Confidence (CMC) Development Strategy. Immunogenicity. Interchangeability. Bridging a New Biologic to Its Reference Biologic. How to Account Covariate Effect to Show Non-Inferiority in Biosimilars. Novel Method in Inference of Equivalence in Biosimilars. Multiplicity Adjustment in Equivalence Using Two One-Sided Tests. Bayesian Methods in Biosimilar Studies.
£114.00
Taylor & Francis Inc Phylogenomic Data Acquisition
Book SynopsisPhylogenomics is a rapidly growing field of study concerned with using genome-wide datausually in the form of DNA sequence locito infer the evolution of genes, genomes, and the Tree of Life. Accordingly, this discipline connects many areas in biology including molecular and genomic evolution, systems biology, molecular systematics, phylogeography, conservation genetics, DNA barcoding, and others. With the advent of Next Generation Sequencing in addition to advances in computer hardware and software over the past decade, researchers can now generate unparalleled phylogenomic datasets that are helping to illuminate many areas in the life sciences. This book is an introduction to the principles and practices of gathering these data. Phylogenomic Data Acquisition: Principles and Practice is intended for a broad cross-section of biologists and anyone else interested in learning how to obtain phylogenomic data using the latest methods.Trade Review"There is definitely a need for this book written in the language of the phylogeneticist. The general organization of the book is good. This book addresses a broad range of topics in a way that makes them comprehensible to people who are not experts in bioinformatics and will be extremely influential. Jennings has been in on the ground floor of the multilocus coalescent revolution in phylogenetics."Jim McGuire, University of California Berkeley"Genome sequencing technologies and data collection techniques are changing rapidly, and this book is a great resource for getting up to speed in this exciting field. Jennings outlines the essential data collection strategies that all students entering the field of molecular systematics need to know. "Adam Leaché, University of Washington, Seattle"This new book by evolutionary biologist Bryan Jennings brings together a wealth of useful information allowing researchers to move from start to finish in the rapidly changing field of phylogenomics. It details step-by-step protocols and provides masterful summaries of best practices for the modern phylogeneticist. Graduate students, postdoctoral fellows and principal investigators will find this book extremely useful. Jennings cuts through the jungle of sometimes conflicting information and provides cogent reviews of important topics and guidelines for avoiding common pitfalls."Scott Edwards, Harvard UniversityTable of ContentsIntroduction. PHYLOGENOMIC DATA CHARACTERISTICS AND ACQUISITION. Genomes, Molecular Evolution, and Molecular Markers. DNA Extraction. PCR Theory and Methodology. Loci Acquisition. Sanger and Next Generation DNA Sequencing. UNDERSTANDING AND MAKING GENE TREES: THE UNITS OF PHYLOGENOMIC ANALYSIS. Gene Tree Inference. Advanced Gene Tree Inference. PHYLOGENOMIC ANALYSIS: USING GENE TREES TO ANSWER EVOLUTIONARY QUESTIONS. Gene and Genome Evolution. Primer of Coalescent Theory. Species Tree Inference. Phylogeography I. Phylogeography II. DNA Barcoding and Forensics. Future Prospects. References. Glossary. Answers to End-of-chapter Questions.
£166.25
Taylor & Francis Inc Fennemas Food Chemistry
Book SynopsisThis latest edition of the most internationally respected reference in food chemistry for more than 30 years, Fennema's Food Chemistry, 5th Edition once again meets and surpasses the standards of quality and comprehensive information set by its predecessors. All chapters reflect recent scientific advances and, where appropriate, have expanded and evolved their focus to provide readers with the current state-of-the-science of chemistry for the food industry. This edition introduces new editors and contributors who are recognized experts in their fields.The fifth edition presents a completely rewritten chapter on Water and Ice, written in an easy-to-understand manner suitable for professionals as well as undergraduates. In addition, ten former chapters have been completely revised and updated, two of which receive extensive attention in the new edition including Carbohydrates (Chapter 3), which has been expanded to include a section on MaTrade ReviewSource: Grasas y Aceites Vol 68, No 4 (2017)Name: F. J. HidalgoIn summary, an updated version of this classic textbook in Food Chemistry that has been employed by numerous students and researchers. This new edition maintains the same spirit that previous editions and will continue being as useful as before for both Food Chemistry courses and those wanting to have a deep introduction to some unknown aspects in Food Chemistry.Table of ContentsIntroduction. Major Food Components. Water and Ice. Carbohydrates. Lipids. Amino Acids, Peptides, and Proteins. Enzymes. Dispersed Systems: Basic considerations. Minor Food Components. Vitamins. Minerals. Colorants. Flavors. Food Additives. Bioactive Substances. Nutraceuticals and Toxicants. Food Systems. Characteristics of Milk. Post-Mortem Physiology of Edible Muscle Tissues. Post-harvest Physiology of Edible Plant Tissues.
£204.25
Taylor & Francis Inc Health Technology Assessment
Book SynopsisThe term health technology refers to drugs, devices, and programs that can improve and extend quality of life. As decision-makers struggle to find ways to reduce costs while improving health care delivery, health technology assessments (HTA) provide the evidence required to make better-informed decisions.This is the first book that focuses on the statistical options of HTAs, to fully capture the value of health improvements along with their associated economic consequences. After reading the book, readers will better understand why some health technologies receive regulatory or reimbursement approval while others do not, what can be done to improve the chances of approval, as well as common shortcomings of submissions for drug and device reimbursement.The book begins by contrasting the differences between regulatory approval and reimbursement approval. Next, it reviews the principles and steps for conducting an HTA, including the reasons why different agencies will hTable of ContentsRegulation, Reimbursement and Health Technology Assessment. Requirements and Sources of Data to Complete an HTA. Meta-Analysis. Network Meta-Analysis. Bayesian Methods. Survival Analysis. Costs and Cost of Illness Studies. Health-Related Quality of Life. Missing Data Methods.
£99.75
Taylor & Francis Inc Biocalorimetry
Book SynopsisConnecting past, present, and future instrument development and use, Biocalorimetry: Foundations and Contemporary Approaches explores biocalorimetry's history, fundamentals, methodologies, and applications. Some of the most prominent calorimeter developers and users share invaluable personal accounts of discovery, discussing innovative techniques as well as special and original applications. Wide in scope, the book also covers calorimetry use on membranes, nucleic acids, and proteins and addresses both thermodynamics and kinetics. The book begins with a look at the historical development of calorimeters needed for biological research. It then describes advanced approaches that use high-quality commercial calorimeters to study biochemical and other biological processes. It also shows how novel experimental designs and data analysis procedures are applied to proteins, DNA, membranes, and living matter. Trade Review"This is a highly specialized collection of articles mainly by European chemists, biochemists, and biologists. The article topics surround the history, theory, and application of calorimetry in biology. The measurement of heat absorbed and exuded by matter, due to changes in surrounding temperature, forms the science of relevance to characterize the materials; this can be related to their structures and properties. Historically, calories have been defined as units of heat energy. The focus of several chapters includes the problem of measuring the very small amounts of heat specific to biological matter, which requires very sensitive and sophisticated instruments. In four sections, the articles cover the history and methods of calorimetry, the use of differential scanning and isometric titration calorimetry to characterize specific membranes, the calorimetry of nucleic acids and proteins, and applications of calorimetry to other areas, such as clinical samples, enzymes, and pharmaceuticals. Every article is replete with references, graphs, and mathematical analysis. The index is useful.Summing Up: Recommended. Graduate students, researchers, professionals."—N. Sadanand, Central Connecticut State University, in the January 2017 issue of CHOICE"Whether the reader is new to the area or already an experienced scientist, this book will serve as the ultimate reference in the field of biocalorimetry. The very pioneers that gave us the instrumentation and techniques cover the history and background of biocalorimetry. The ongoing research is described by current experts in different fields of biocalorimetry. Everything is there."—Arne Schön, Research Scientist, Department of Biology, Johns Hopkins University"This book is a much-needed update on the field of biothermodynamics and biocalorimetry. It starts with historical and sometimes personal views from some of the pioneers of this field, followed by reviews on the state of the art of calorimetry application to the study of biomembranes, nucleic acids, and proteins, as well as biomedical applications. I think all newcomers should take the time to read the book from its beginning to grasp how the field started and until the end to have an idea on where it is expanding to."—Watson Loh, Professor of Physical Chemistry, Institute of Chemistry, University of Campinas"This is a highly specialized collection of articles mainly by European chemists, biochemists, and biologists. The article topics surround the history, theory, and application of calorimetry in biology. The measurement of heat absorbed and exuded by matter, due to changes in surrounding temperature, forms the science of relevance to characterize the materials; this can be related to their structures and properties. Historically, calories have been defined as units of heat energy. The focus of several chapters includes the problem of measuring the very small amounts of heat specific to biological matter, which requires very sensitive and sophisticated instruments. In four sections, the articles cover the history and methods of calorimetry, the use of differential scanning and isometric titration calorimetry to characterize specific membranes, the calorimetry of nucleic acids and proteins, and applications of calorimetry to other areas, such as clinical samples, enzymes, and pharmaceuticals. Every article is replete with references, graphs, and mathematical analysis. The index is useful.Summing Up: Recommended. Graduate students, researchers, professionals."—N. Sadanand, Central Connecticut State University, in the January 2017 issue of CHOICE"Whether the reader is new to the area or already an experienced scientist, this book will serve as the ultimate reference in the field of biocalorimetry. The very pioneers that gave us the instrumentation and techniques cover the history and background of biocalorimetry. The ongoing research is described by current experts in different fields of biocalorimetry. Everything is there."—Arne Schön, Research Scientist, Department of Biology, Johns Hopkins University"This book is a much-needed update on the field of biothermodynamics and biocalorimetry. It starts with historical and sometimes personal views from some of the pioneers of this field, followed by reviews on the state of the art of calorimetry application to the study of biomembranes, nucleic acids, and proteins, as well as biomedical applications. I think all newcomers should take the time to read the book from its beginning to grasp how the field started and until the end to have an idea on where it is expanding to."—Watson Loh, Professor of Physical Chemistry, Institute of Chemistry, University of CampinasTable of ContentsIntroduction: Historical and Methodological Context. Membrane Characterization and Partition to Membranes. Nucleic Acids and Proteins: Stability and Their Interactions with Ligands. Calorimetry as a Tool in Applied Fields.
£175.75
Taylor & Francis Inc Fundamentals of Asymmetric Synthesis
Book SynopsisAsymmetric synthesis is an integral part of synthetic organic chemistry. Some of the reactions in this book were known prior to 1980, while several new ones, particularly catalytic asymmetric reactions, have been discovered in the recent years. The impact of this new class of reactions has been impressively extensiveboth on organic and medicinal chemistry. These reactions have been accepted whole-heartedly by synthetic organic chemists in developing shorter routes for complex natural targets as well as in the manufacture of a wide range of drug intermediates.Table of ContentsIntroduction. Terms, Definitions and Concepts in Asymmetric Synthesis. Achiral and Chiral Molecules and Their Properties. Prochirality. Enantioselective and Diastereoselective Synthesis. Methods for Monitoring Enantioselective and Diastereoselective Synthesis. Methods for Inducing Asymmetry. Chiral Substrate Controlled Asymmetric Reactions: Diastereoselection in acyclic systems. Chiral auxiliary controlled asymmetric reactions—Asymmetric α-alkylations. Chiral Stoichiometric Reagent Controlled Asymmetric Synthesis: Chiral Boron Reagents. Chiral Catalyst Mediated Asymmetric Reactions: Enzymes. Chiral Organometallic Catalysed Asymmetric Reactions: Sharpless Asymmetric Epoxidations, Dihydroxylations and Aminohydroxylations. Chiral Organometallic Catalysed Asymmetric Reactions. Organocatalysts in Asymmetric Synthesis—Chiral Additive Mediated Reactions. Asymmetric Aldol Reaction. Asymmetric Diels–Alder reactions. Stereoselective Synthesis and Stereospecific Synthesis. Index.
£175.75
Taylor & Francis Inc Pharmaceuticals to Nutraceuticals
Book SynopsisRecently, there has been a fundamental shift in the global health and wellness industry from disease treatment to preventing chronic diseases. The use of nutraceuticals and functional foods in prevention efforts could lead to a decreased dependency on drugs. The pharmaceutical industry recognizes this shift; however, serious concerns have arisen regarding the claimed efficacy, quality, and safety of products used as medical foods.This book examines the consumer and industry mindshift, including the scientific evidence of these foods as effective adjuncts to pharmacotherapy during all stages of treatment of various diseases, thus indicating that pharmaceuticals and nutraceuticals can and should coexist. It details quality, safety, and efficacy of foods, drugs, and nutrients; marketing and product positioning; regulatory perspectives; biomarkers and metabolites; probiotics; food/drug interactions; and future industry trends. In addition, food bioactives represent diet-basedTrade ReviewPharmaceuticals to Nutraceuticals: A Shift in Disease Prevention considers the recent shift in the health and consumer industries from treating diseases and conditions to preventing them, and offers a scientific survey of the use of nutraceuticals and foods in these prevention efforts. While the pharma industry has acknowledged this change, there remain many questions about quality and product safety when it comes to medicinal foods - questions surveyed in this book, which gathers under one cover the scientific studies and research surrounding food, nutrient and drug applications, marketing, and claims. Today, human diet is believed to have a major influence on both the development and prevention of age-related chronic inflammatory diseases such as metabolic syndrome, diabetes, heart and lung diseases, cancer, osteoporosis, arthritis, and dementia. Prescription-based food recommending system is getting more popular today. The underlying fact is ‘NextGen’ population today is seeking for preventive evidence based solutions and want to empower the responsible management of health. College-level students of health and nutrition as well as practicing professionals in these fields will appreciate the inclusion of many different studies and assessments of therapies and their results, and will find this global focus offers a solid contrast and assessment of food-based prevention claims. The result is an in-depth collection highly recommended for any professional or college collection.Source: Midwest BookreviewTable of ContentsIntroduction. Quality-Safety-Efficacy: 3 Mantras. Marketing & Product Positioning. Regulatory Perspective. Science Underpinning. New Journeys through Categorization. Future Trends.
£166.25
Taylor & Francis Inc Obesity
Book SynopsisObesity is considered a complex and multifactorial disease. Its treatment, therefore, must also be multimodal and tailored to meet the needs of each patient. Obesity: Evaluation and Treatment Essentials presents a wide spectrum of practical treatment protocols for obesity including exercise, pharmacology, behavior modification, and dietary factors, from the point of view of the practicing physician.The book includes information about the new pharmacotherapy available for the treatment of obesity. It also includes a chapter on medical treatment of pediatric obesity that identifies the special needs of children and outlines approaches for managing the obese child. A chapter on binge eating disorder has been added and the information on pharmacology of bariatric medicine has been updated. The book addresses various dietary interventions such as low-calorie balanced diets, low-carbohydrate diets, and very-low-carbohydrate diets while also exploring the comorbidities of obeTable of ContentsObesity: The Scope of a Growing Problem. Etiologies of Obesity. Health Hazards of Obesity. Evaluation of the Obese Patient. Dietary Treatment of the Obese Individual. The Role of Physical Activity in the Treatment of the Obese Individual. Behavioral Modification. Pharmacotherapy. Maintenance of Weight Loss. Surgical Treatment of the Obese Individual. Medical Treatment of Pediatric Obesity. Binge Eating Disorder (BED): Etiology, Assessment, Diagnosis and Treatment. Current Research and Future Hope. Appendix A: Notes on Nutrition for Obesity Medicine. Appendix B: Behavioral Modification Attachments. Appendix C: ASBP Algorithm.
£137.75
Taylor & Francis Inc Chinese Dates
Book SynopsisChinese Dates: A Traditional Functional Food delivers unique information on Chinese dates (jujubes) as typical ethical foods and traditional health-promoting foods. It conveys a better understanding of Asian food cultures and provides historical information in regard to traditional functional foods and their dietary applications. It discusses the health-promoting benefits of a wide variety of jujube fruits and covers different jujube products, such as jujube fruit juice and cakes. It also looks into the many kinds of jujube fruit-based medicated diets, describes innovative new processing technologies and novel jujube products, and examines ethnomedicinal uses, pharmacological activity, and phytochemical constitutes of jujubes.The book's four sections and nineteen chapters provide information on Chinese date's origin, distribution, varieties, chemical composition, biochemical properties, traditional products and technology, innovative processing technology, foTable of ContentsORIGINAL, DISTRIBUTION, AND GROWING CONDITION OF CHINESE DATES (JUJUBES). CHEMICAL AND BIOCHEMICAL PROPERTIES AND HEALTH BENEFITS OF CHINESE DATES (JUJUBES). CHINESE DATE (JUJUBE) PRODUCTS AND POSTHARVEST TECHNOLOGY. CHINESE DATE (JUJUBE) INDUSTRY IN DIFFERENT COUNTRIES.
£204.25
Taylor & Francis Inc Cilia
Book SynopsisThe scope of the book is to highlight the diverse roles of cilia in human development and disease. Almost all cell types form cilia and although they were first detected about 200 years ago, their significance was unclear. In the past ten years, it has become obvious that cilia have got sensory functions, as well as roles in motility and their mis-formation or the deregulation of the signaling pathways they control has been associated with defective development and human disease. Although research has concentrated on the role of the cilium in each organ, no effort has been made so far to bring all this information together and relate it to the various human diseases. This book aims to gather all the expertise that has been acquired on primary cilia and translate it into a medical and research context that will be of interest to postgraduate students, researchers, medics and scientists.Table of ContentsCilia in the Brain – Development and Disease. Cilia in Lung Development and Disease. The Role of Cilia in Heart Development and Disease. Cilia in Kidney Development and Disease. The Role of Cilia in Pancreatic Development and Disease. The Role of Cilia in Skeletal Development and Disease. The Role of Cilia in Development and Disease of the Eye. The Role of Cilia in the Auditory System.
£142.50
Taylor & Francis Inc Molecular Mechanisms of Skin Aging and AgeRelated
Book SynopsisOur skin changes as we age. It becomes thinner and loses fat, making it less plump and smooth. Clinically, aged skin is characterized by wrinkles, sagging, age spots and dryness. Emphasizing laboratory and clinical research, this book comprehensively describes the molecular mechanisms of human skin-aging and age-related skin diseases. This includes molecular understanding of the development of aging skin and its prevention as well as mechanisms-based clinical rejuvenation. The book also focuses on research to develop mechanisms-based anti-skin-aging products.Table of ContentsOverview. Human Skin Natural Aging and Sun-induced Premature Aging. Molecular Mechanisms of Human Skin Aging. Age-Related Skin Diseases (Skin Cancer and Wound Healing in Elderly). Prevention of Human Skin Aging and Age-Related Skin Diseases. Human Skin Rejuvenation.
£175.75
Taylor & Francis Inc Smart Biomaterial Devices
Book SynopsisPolymers have emerged as one of the most innovative classes of materials in modern materials science, leading to new applications in medicine and pharmacy. This book offers a convincing and understandable approach to polymer biomaterial devices being used in various areas related to biomedical and pharmaceutical fields. The polymer materials finding application as biomaterials are discussed and described in detail pertaining to the areas of artificial implants, orthopedics, ocular devices, dental implants, drug delivery systems, burns and wounds. Table of ContentsIntroduction. Polymers in Dental Devices. Polymers in Orthopedic Devices. Polymers in Drug Delivery Systems. Polymers in Wound Dressing Materials. Polymers in Tissue Engineering. Polymers in Ocular Devices. Polymers in Cardiovascular Systems. Present Market of Available Polymer Biomedical Devices. Present Challenges and Future Prospects.
£137.75
Taylor & Francis Inc Vitamin B12
Book SynopsisCobalamin (vitamin B12) was discovered in the first half of the 20th century. Vast amount of information on the role of the vitamins in human health and disease became available. Cobalamin science was, however, based on theoretical concepts that have been accepted without further proof of facts and hypotheses. Recently, the breath-taking pace of development in research technologies has changed our understanding for the role of nutrients and the complex interaction between diet, environment and diseases. Conditions like aging, diet and drugs increase the risk of developing cobalamin deficiency, probably because of diminished ability to liberate, absorb or distribute the food-derived vitamin. From a basic science point of view, understanding of the transport and function of the vitamin, may pave the road for using this system for drug delivery. This book represents up-to-date literature on the discoveries and developments in the field of cobalamin. It includes multifacetTable of ContentsMilestones in the Discovery of Pernicious Anemia and Its Treatment. Nutritional and Biochemical Aspects of Cobalamin throughout Life. Intracellular Processing and Utilization of Cobalamins. Inherited Defects of Cobalamin Metabolism. Conditions and Diseases that Cause Vitamin B12 Deficiency: Form Metabolism to Diseases. Vitamin B12 Deficiency in Developing and Newly Industrialising Countries. Vitamin B12 in Neurology and Aging. The Role of Cobalamin in the Central and Peripheral Nervous Systems: Mechanistic Insights. Laboratory Markers and Diagnosis of Cobalamin Deficiency. Cobalamin during Pregnancy and Lactation. Vitamin B12 after Birth and during Early Life. Cobalamin – Folate Interactions. Extreme Vitamin B12 Concentrations in Clinical Practice in the Absence of Symptoms or B12 Treatment. Vitamin B12 and Drug Development.
£185.25
Taylor & Francis Inc Mechanisms Linking Aging Diseases and Biological
Book SynopsisThis book focuses on four of the hallmarks of aging: aspartic acid racemization, advanced glycation end products, telomere shortening and mitochondrial mutations; describing their role in aging and diseases; and their application to age-at-death estimation in forensic sciences in greater depth, displaying the interconnecting pathways among these processes. An additional chapter related to Epigenetics and its role in aging, diseases, and forensic age estimation is also included. This book is aimed at a broad audience: from students being introduced to aging, diseases, and forensic science research to scientists in biomedicine and forensics complementing their knowledge in their respective fields while also increasing their knowledge in other disciplines.Table of ContentsAspartic Acid Racemization. Introduction to Aspartic Acid Racemization. Aspartic Acid Racemization on Aging. Aspartic Acid Racemization and Aging in Cartilaginous Tissue. Racemization and isomerization of Aspartyl Residues in Amyloid Peptides Involved in the Development of Alzheimer´s Disease. Aspartic Acid Racemization: Applications to Forensic and Archaeological Age Estimation. Advanced Glycation Endproducts. Advanced Glycation Endproducts: An Introduction. Advanced Glycation and Aging. AGE-RAGE Axis in the Aging and Diabetic Heart: Prime Target for Adjunctive Therapeutic Intervention. Advanced Glycation Endproducts in Aging Skin. Advanced Glycation Endproducts and Neurological Diseases. Advanced Glycation Endproducts for Age at Death Estimation. Telomeres. Introduction to Telomere Biology. Role of Telomeres in Aging. Telomeres and Cardiovascular Disease: Facts, Controversies and Limitations. Telomeres in Cancer. Forensic Application of Telomere Shortening in Age-at-death Estimation. Mitochondrial DNA Mutations. Introduction to Mitochondria Biology. Mitochondrial DNA Mutations and Aging. Mitochondrial DNA Mutations and Mitochondrial Diseases. Reproductive Approaches to Prevent the Transmission of Mitochondrial Diseases. Mitochondrial DNA Mutations and Neurodegenerative Diseases. An Overview of mtDNA Analysis for Age-at-death Estimation in Forensic Sciences. Epigenetics. Epigenetics: Its Role in Aging, Diseases and Biological Age Estimation.
£155.00
Taylor & Francis Inc Regenerative Medicine Technology
Book SynopsisMiniaturization in the fields of chemistry and molecular biology has resulted in the lab-on-a-chip. Such systems are micro-fabricated devices capable of handling extremely small fluid volumes facilitating the scaling of single or multiple lab processes down to a microchip-sized format. The convergence of lab-on-a-chip technology with the field of cell biology facilitated the development of organ-on-a-chip systems. Such systems simulate the function of tissues and organs, having the potential to bypass some cell and animal testing methods. These technologies have generated high interest as applications for disease modeling and drug discovery. This book, edited by Drs. Sean Murphy and Anthony Atala, provides a comprehensive coverage of the technologies that have been used to develop organ-on-a-chip systems. Known leaders cover the basics to the most relevant and novel topics in the field, including micro-fabrication, 3D bio-printing, 3D cell culture techniques, biosensor designTable of ContentsIntroduction. Microfabrication and 3D Bioprinting. 3D Cell Culture/Tissue Spheroids. Biosensors and Microelectronics. Microfluidics. Big Data/Predictive Analysis. Lab-on-a-Chip. Lung-on-a-Chip. Liver-on-a-Chip. Heart-on-a-Chip. Skin-on-a-Chip. Kidney-on-a-Chip. Body-on-a-Chip. Liver Cancer-on-a-Chip. Lung Cancer-on-a-Chip. Breast Cancer-on-a-Chip. Cancer Metastasis-on-a-Chip. Cancer Microenvironment-on-a-Chip. Disease Modeling. Toxicology Testing. Detection of Bioweapon Pathogens. Personalized Medicine.
£175.75
Taylor & Francis Inc Applied Molecular Biotechnology
Book SynopsisApplied Molecular Biotechnology: The Next Generation of Genetic Engineering explains state-of-the-art advances in the rapidly developing area of molecular biotechnology, the technology of the new millennium. Comprised of chapters authored by leading experts in their respective fields, this authoritative reference text: Highlights the latest omics-based tools and approaches used in modern biotechnology Explains how various molecular biology technologies can be used to develop transgenic plants and how those plants can meet growing food and plant-derived product demands Discusses chloroplast gene expression systems, mitochondrial omics, plant functional genomics, and whole-genome resequencing for crop improvement Explores plantmicrobe and plantinsect interactions affecting plant protection and productivity Covers animal models, pharmacogenomics, human tissue banking, and the molecular diagnosis of diseases such as cervicalTrade Review"... timely and very much needed. … a comprehensive … [book] covering all important aspects of the technology."—From the Foreword by Dr. Kauser Abdulla Malik, HI, SI, TI, Distinguished National Professor, Dean for Postgraduate Studies, Forman Christian College (A Chartered University), Lahore, Pakistan "This book is certainly a very valuable guide for any safety manager intending to build and maintain an effective safety activity. The focus on human factors is on the most relevant aspects as much as the need to define the most valuable ways to perform a retrospective analysis of occurrences. The implementation of a Safety Management System is the essential instrument on which safety processes and company operations are based. The correct approach to dealing with human factors and in particular to analyzing the contribution pf human errors to incident causation is a crucial pillar, but not the only one, on which the entire foundation of organizational safety is based. This book offers a valuable support in ensuring this is achieved." —Cogn Tech Work, 2016 "... timely and very much needed. … a comprehensive … [book] covering all important aspects of the technology."—From the Foreword by Dr. Kauser Abdulla Malik, HI, SI, TI, Distinguished National Professor, Dean for Postgraduate Studies, Forman Christian College (A Chartered University), Lahore, Pakistan "This book is certainly a very valuable guide for any safety manager intending to build and maintain an effective safety activity. The focus on human factors is on the most relevant aspects as much as the need to define the most valuable ways to perform a retrospective analysis of occurrences. The implementation of a Safety Management System is the essential instrument on which safety processes and company operations are based. The correct approach to dealing with human factors and in particular to analyzing the contribution pf human errors to incident causation is a crucial pillar, but not the only one, on which the entire foundation of organizational safety is based. This book offers a valuable support in ensuring this is achieved." —Cogn Tech Work, 2016 Table of ContentsEmerging Tools and Approaches to Biotechnology in the Omics Era. Plant Molecular Biology: Tools to Develop Transgenics. Plant Molecular Biotechnology: Applications of Transgenics. The Chloroplast Gene-Expression System. Molecular Biology of Mitochondria: Genome, Transcriptome, and Proteome. Plant Functional Genomics: Approaches and Applications. Whole-Genome Resequencing: Current Status and Future Prospects in Genomics-Assisted Crop Improvement. Molecular Biotechnology of Plant–Microbe–Insect Interactions. Biotechnology for Improved Crop Productivity and Quality. Overview of Methods to Unveil the Epigenetic Code. Animal Models and Biomedical Research. Variations in Our Genome: From Disease to Individualized Cure. Molecular Biotechnology for Diagnostics. Techniques for Cervical Cancer Screening and Diagnosis. Type 2 Diabetes Mellitus, Obesity, and Adipose Tissue Biology. Human Tissue Banking and Its Role in Biomedical Research. Microbial Biotechnology. Molecular Biology of Viruses: Disease Perspective. Viral Biotechnology: Production Perspective. Cell-Free Biosystems. Magnetic Nanoparticles with Multifunctional Water-Soluble Polymers for Bioapplications. Industrial Biotechnology: Its Applications in Food and Chemical Industries. Environmental Biotechnology: Approaches for Ecosystem Conservation. Marine Biotechnology: Focus on Anticancer Drugs. Engineering Genomes for Biofuels.
£204.25
Taylor & Francis Inc WebGL Insights
Book SynopsisGiven its ubiquity, plugin-free deployment, and ease of development, the adoption of WebGL is on the rise. Skilled WebGL developers provide organizations with the ability to develop and implement efficient and robust solutionsâcreating a growing demand for skilled WebGL developers.WebGL Insights shares experience-backed lessons learned by the WebGL community. It presents proven techniques that will be helpful to both intermediate and advanced WebGL developers.By focusing on current and emerging techniques, the book demonstrates the breadth and depth of WebGL. Readers will gain practical skills to solve problems related to performance, engine design, shader pipelines, rendering, mobile devices, testing, and more.Throughout the book, experienced WebGL engine and application developers, GPU vendors, browser developers, researchers, and educators share their unique expertise based on their real-world experiences. This includes hardware vendors sharing pTrade ReviewThis book and the accompanying website represent the epitome of the web’s sharing culture: a curated collection of leading-edge techniques and insights, with online source code and live demonstrations. In this book, engine authors present their strategies for achieving high-performance, good scalability, and leading-edge visuals. Educators share their experience in moving real-time computer graphics courses to the web and WebGL. Application developers and toolchain authors share their experiences both building large, new JavaScript code bases and bringing existing C++ code bases to the web. Graphics researchers show how to implement leading-edge rendering techniques in WebGL, allowing these techniques to be deployed seamlessly to hundreds of millions of devices and billions of people. Visualization researchers demonstrate how to render huge data sets with high performance and high impact. Interaction researchers provide insights into effective navigation and interaction paradigms for 3D applications. Finally, browser and GPU implementers give a look under the hood of WebGL implementations to help developers tune their code for best performance on a range of devices.This book contains a wealth of information and will be a treasured reference for years to come. —Ken Russell, Khronos WebGL Working Group Chair, Software Engineer, Google Chrome GPU TeamTable of ContentsWebGL Implementations. Moving to WebGL. Mobile. Engine Design. Rendering. Visualization. Interaction.
£123.50
Taylor & Francis Inc Green Coffee Bean Extract in Human Health
Book SynopsisThe role of green coffee bean (GCB) in human health is of emerging interest to the nutraceutical field, especially given its role in improving metabolic syndrome, including weight management, hypertension, diabetes, and neuroprotection. GCB extract contains a novel antioxidant known as chlorogenic acid (also caffeoylquinic acid), which has been shown to positively affect blood pressure, brain health, diabetes, and weight management. This book provides information on the diverse health benefits of green coffee bean extract, molecular mechanisms and signaling pathways, safety of GCB, dosage, and recommended usage. It focuses on the chemistry, biochemistry, pharmacology, and safety of GCB extract.GCB extract has brought a remarkable revolution in the nutraceutical marketplace. However, some controversies have been demonstrated recently. This book presents the state-of-the-art research studies from eminent scientists around the world on the potential and diversified health beTable of ContentsIntroduction. An Overview on Green Coffee Bean. Chlorogenic Acid: An Integral Constituent of Green Coffee Bean. Diverse Health Benefits of Green Coffee Bean Extract. Molecular Mechanisms and Signaling Pathway. Safety of Green Coffee Bean. Dosage & Recommended Use.
£175.75
Taylor & Francis Inc Music Data Analysis
Book SynopsisThis book provides a comprehensive overview of music data analysis, from introductory material to advanced concepts. It covers various applications including transcription and segmentation as well as chord and harmony, instrument and tempo recognition. It also discusses the implementation aspects of music data analysis such as architecture, user interface and hardware. It is ideal for use in university classes with an interest in music data analysis. It also could be used in computer science and statistics as well as musicology.Trade Review " . . . what makes this book unique is that it covers a much broader range of topics. Not only does it present a concrete tutorial on signal processing and music information retrieval . . . , but it also talks about interesting topics such as emotions, automatic composition, hardware, and others, so readers are sure to find novel information . . . In summary, MusicDataAnalysis is well thought-out and well written. It chooses to emphasize a breadth of topics rather than specialize in specific ones. This book nicely accomplishes its goal of serving as an introductory textbook for music research. It is also a very useful reference and valuable resource for individuals seeking new directions in the field." ~Yupeng Gu, Journal of the American Statistical Association". . . the book is impressive in its structure, comprehensiveness, clarity and accuracy. . . This text has staked out a specialised interdisciplinary niche, but as a self-contained guide to computational methods for music, I think it unlikely to be surpassed in the near future." ~David Bulger, Australian & New Zealand Journal of Statistics"Theoretical and practical exercises based on R and MATLAB are provided in the book’s web site, as well as example data sets. The book is very clearly written, and the style is fairly uniform despite the large number of authors. In sum, a very useful and enjoyable book." ~Ricardo Maronna, Stat Papers" . . . what makes this book unique is that it covers a much broader range of topics. Not only does it present a concrete tutorial on signal processing and music information retrieval . . . , but it also talks about interesting topics such as emotions, automatic composition, hardware, and others, so readers are sure to find novel information . . . In summary, MusicDataAnalysis is well thought-out and well written. It chooses to emphasize a breadth of topics rather than specialize in specific ones. This book nicely accomplishes its goal of serving as an introductory textbook for music research. It is also a very useful reference and valuable resource for individuals seeking new directions in the field." ~Yupeng Gu, Journal of the American Statistical Association". . . the book is impressive in its structure, comprehensiveness, clarity and accuracy. . . This text has staked out a specialised interdisciplinary niche, but as a self-contained guide to computational methods for music, I think it unlikely to be surpassed in the near future." ~David Bulger, Australian & New Zealand Journal of Statistics"Theoretical and practical exercises based on R and MATLAB are provided in the book’s web site, as well as example data sets. The book is very clearly written, and the style is fairly uniform despite the large number of authors. In sum, a very useful and enjoyable book." ~Ricardo Maronna, Stat PapersTable of ContentsMUSIC AND AUDIO. Introduction. The Musical Signal - Physically and Psychologically. Musical Structures and Their Perception. Digital Signal Processing. Digital Representation of Music. Signal-level Features. METHODS. Foundations of Statistics. Optimization. Unsupervised Classification. Supervised Classification. Evaluation. Feature Processing. Feature Selection. APPLICATIONS. Transcription. Segmentation. Instrument Recognition. Chord and Harmony Recognition. Tempo Recognition. Emotions. Structuring Of Music Collections. Music Recommendation. Automatic Composition. IMPLEMENTATION. Architecture. User Interaction. Hardware.
£64.99
Taylor & Francis Inc Forensic Science Handbook Volume I
Book SynopsisOriginally published in 1982 by Pearson/Prentice-Hall, the Forensic Science Handbook, Third Edition has been fully updated and revised to include the latest developments in scientific testing, analysis, and interpretation of forensic evidence. World-renowned forensic scientist, author, and educator Dr. Richard Saferstein once again brings together a contributor list that is a veritable Who's Who of the top forensic scientists in the field. This Third Edition, he is joined by co-editor Dr. Adam Hall, a forensic scientist and Assistant Professor within the Biomedical Forensic Sciences Program at Boston University School of Medicine. This two-volume series focuses on the legal, evidentiary, biological, and chemical aspects of forensic science practice.The topics covered in this new edition of Volume I include a broad range of subjects including: Legal aspects of forensic science Analytical instrumentation to include: microspectrophotometry, infrared Spectroscopy, gTable of Contents1. Legal Aspects of Forensic Science[Gil I. Sapir]2. Forensic Paint Examination[Diana Wright, Daniel Kirby, and John Thornton]3. The Forensic Identification and Association of Human Hair[Richard E. Bisbing]4. A Guide to the Analysis of Forensic Household Dust Specimens and Their Statistical Significance [Nicholas Petraco and Nicholas D. K. Petraco]5. Fundamentals of Visible Microspectrophotometry in Forensic Science[Michael B. Eyring]6. Infrared Spectroscopy in the Forensic Sciences[Edward M. Suzuki]7. Forensic Characterization and Comparisons of Inks[Tatiana Trejos and Jose Almirall]8. Forensic Gas Chromatography[Thomas A. Brettell and David T. Stafford]9. Forensic Applications of High Performance Liquid Chromatography and Capillary Electrophoresis[David Northrup]10. Forensic Mass Spectrometry[Adam B. Hall and Richard Saferstein]11. Analysis of Body Fluids in Sexual Assault Cases[Edwin Jones]12. The Application of Capillary Electrophoresis in Forensic DNA Analysis[Bruce McCord]
£153.84
Taylor & Francis Inc Carbocation Chemistry
Book SynopsisCarbocation chemistry is not only fundamental to the advancement of organic chemistry, it also has found widespread applications in organic synthesis. It is not an exaggeration to say that carbocation chemistry is part of the foundation of organic chemistry. Carbocation Chemistry: Applications in Organic Synthesis provides a panoramic view of carbocation chemistry with an emphasis on synthetic applications. This book is an invaluable tool for organic, medicinal and analytical chemists, including those working in biochemistry as well as the petroleum, plastics and pharmaceutical industries. It is also suitable for upper level undergraduates and graduates in organic chemistry, biochemistry and medicinal chemistry.Table of ContentsChapter 1. Introduction Nomenclature, Structure, and Stability Generation of Carbocations The Non-Classical Ion Controversy Electrophilic Addition to Alkenes Electrophilic Aromatic Substitution Elimination reactions Rearrangement Reactions of Carbocations References Chapter 2. Nucleophilic Aliphatic Substitution – SN1 Introduction -Activated Alcohols—Brønsted Acids -Activated Alcohols—Lewis Acids Alkylation of Aldehydes and Ketones Glycosylation Friedel–Crafts Alkylation and Acylation Electrophilic Fluorination Using Fluoronium Ion Miscellaneous SN1-related Reactions References Chapter 3. Nucleophilic Aliphatic Substitution – SN2 Construction of Quaternary Stereogenic Centers Sulfur Chemistry Organometallic Chemistry Macrocyclization Glycosylation Nucleoside Analogues N-Alkylation Cyclotetraphosphazenes Conformationally Locked Tetrahydropyran Ring The Ionic Liquid Effect Silver Chemistry References Chapter 4. Electrophilic Addition to Alkenes Introduction Cyclopropanation Hydroboration/Oxidation The Pauson–Khand Reaction Prins Reaction Schmidt Reaction Halogenation Oxymercuration/Reduction Epoxidation Gold-Catalyzed Alkyne Hydration Conclusion References Chapter 5. Electrophilic Aromatic Substitution Introduction Nitration Halogenation Friedel–Crafts Alkylation Friedel–Crafts Acylation Applications of Friedel–Crafts Reaction on Total Synthesis Miscellaneous Electrophilic Aromatic Substitution Reactions References Chapter 6. Fragmentation and Rearrangement Reactions Claisen Rearrangements Cope Rearrangements Cope Rearrangements Aldehyde (or Ketone) Formation Rearrangements Carboxylic Acid Formation Rearrangements Alcohol Formation Rearrangements Amine Formation Rearrangement Amides Hydrocarbon Rearrangements Oxacyclic, Carbocyclic, Oxazoles, Tetrahydrapuran and Tetrahydropuran Formation Rearrangements Rearrangements resulting in less common functional groups Fragmentations References
£175.75
Taylor & Francis Inc Forensic Anthropology
Book SynopsisThis robust, dynamic, and international field has grown to include interdisciplinary research, continually improving methodology, and globalization of training. Reflecting the diverse nature of the science from experts who have shaped it, Forensic Anthropology: A Comprehensive Introduction Second Edition builds off of the success of the first edition and incorporates standard practices in addition to cutting-edge approaches in a user-friendly format, making it an ideal introductory-level text.Table of Contents AcknowledgementsAbout the EditorsAbout the ContributorsPrefacePart 1: Forensic Anthropology and the Crime SceneChapter One: Forensic Anthropology in the United States: Past and PresentMariaTeresa A. Tersigni-Tarrant and Natalie R. LangleyChapter Two: Skeletal Remains as EvidenceMarin A. Pilloud and MariaTeresa A. Tersigni-TarrantChapter Three: Forensic Archaeology: Survey Methods, Scene Documentation, Excavation, and Recovery MethodsDenise ToChapter Four: Forensic TaphonomyJames Pokines and MariaTeresa A. Tersigni-TarrantPart 2: The Skeleton and Skeletal DocumentationChapter Five: Human OsteologyMariaTeresa A. Tersigni-Tarrant and Natalie R. LangleyChapter Six: Human Odontology and the Dentition in Forensic AnthropologyDebra Prince Zinni and Kate M. CrowleyChapter Seven: Skeletal Examination and DocumentationLee Meadows JantzPart 3: Skeletal Individuation and AnalysesChapter Eight: Sex Estimation of Unknown Human RemainsGregory E. BergChapter Nine: Ancestry Methods: The Importance, The History And The PracticeM. Katherine Spradley and Katy E. WeisenseeChapter Ten: Age Estimation MethodsNatalie R. Langley, Alice F. Gooding, MariaTeresa A. Tersigni-TarrantChapter Eleven: Stature EstimationNatalie R. LangleyChapter Twelve: Pathological Conditions as Individuating Traits in a Forensic ContextDavid Hunt and Kerriann MardenChapter Thirteen: Analysis of Skeletal TraumaNatalie R. LangleyChapter Fourteen: Introduction to Fordisc 3 and Human Variation – StatisticsRichard L. Jantz and Stephen D. OusleyPart 4: Human Identification and Advanced Forensic Anthropology ApplicationsChapter Fifteen: Time Since Death Estimation and Bone Weathering: The Postmortem IntervalRebecca J. Wilson-Taylor and Angela M. DautartasChapter Sixteen: Methods of Personal IdentificationAngi M. Christensen and Bruce E. AndersonChapter Seventeen: Mass Fatalities, Mass Graves and the Forensic Investigation of International CrimesPierre Guyomarc’h and Derek CongramChapter Eighteen: Advanced Scene Topics: Fire and ComminglingJoanne Bennett Devlin and Nicholas P. HerrmannAppendix A: Application of Dentition In Forensic AnthropologyDebra Prince Zinni and Kate M. CrowleyAppendix B: Age Estimation in Modern Forensic AnthropologyBridget F. B. Algee-HewittGlossaryIndex
£82.64
Taylor & Francis Inc Gap Junction Channels and Hemichannels
Book SynopsisGap junction channels are a group of intercellular channels expressed in tissues and organs to synchronize many physiological processes. A gap junction channel is formed by the docking of two hemichannels, and each hemichannel is a hexamer of connexins. The field of gap junction channel and hemichannel research has recently exploded and became one of the most active areas of cell biology. Numerous novel approaches and techniques have been developed, but there is no single book dedicated to the unique techniques and protocols employed for the research on these large pore channels. This book fills the gap and focuses on protocols, approaches and reviews of gap junction channels and connexin hemichannels. It will be a useful reference for graduate students, postdoctoral fellows and researchers. Anyone with an interest in gap junction channels and hemichannels will need this summary of state-of-the-art techniques and protocols.Table of ContentsGap junction channels. Bioinformatics analysis of connexin genes. Structural approaches on gap junction channels. Fluorescent label of connexins. Functional study of gap junction channel gating. Quantitative measurement of dye transfer. Permeability. Pharmacology of gap junction channels. Gap junction mimetic piptides. Gap junction hemichannels. Dye uptake and ATP release. Functional study of hemichannel current. Connexin purification and reconstitution in lipid bilayers. Hemichannel function in the ovary. Pannexin channels. Functional study pannexin channels. Pannexin channels in vasculature. Pharmacology of pannexin channels. Dye uptake and ATP release.
£171.00
Taylor & Francis Inc Wheelchair Skills Assessment and Training
Book SynopsisThis book provides a wide spectrum of readers with comprehensive but easily understandable protocols for the assessment and training of wheelchair skills. The Wheelchair Research Team at Dalhousie University and the Capital District Health Authority in Halifax (lead by the author) have focused on wheelchair safety and performance for three decades, as exemplified through the Wheelchair Skills Program. This is considered the top such program in the world. This new book is largely based on this program which has been accessed and utilized by over 75,000 people in 177 countries since 2007. Table of ContentsIntroduction to the WSTP, General Background on Motor Skills Learning, Specific Issues fo Importance for Motor Skills Learning, Lesson Plans, Skill Groups. Individual Skills, Games
£142.50
Taylor & Francis Inc Schistosoma
Book SynopsisApart from malaria, schistosomiasis is the most prevalent parasitic infection in the world. It affects more than 200 million people in 76 tropical and subtropical countries, causing great suffering and resulting in thousands of deaths. Written by world authorities, this book examines many aspects of the biology, pathology, and control of the schistosoma parasite. Ranging in topic from infection in Pharaonic Egypt, through DNA relationships and biological systems, to advances in development of vaccines against the parasite, this book is a comprehensive text written for researchers and medical professionals alike.Table of ContentsOrigins and Evolutionary Radiation of Schistosoma. Schistosomiasis: Paleopathological Perspectives and Historical Notes. Life Cycles of Schistosomiasis. Schistosoma Intermediate Host Snails. Schistosoma Egg. Miracidium of Schistosoma. Schistosoma Sporocysts. Cercaria of Schistosoma. Schistosomula. Tegument and External Features of Schistosoma. Alimentary Tract of Schistosoma. Nervous and Sensory System of Schistosoma. Reproductive System of Schistosoma. Spermatozoa, Spermatogenesis and Fertilization in Schistosoma. Ova and Oogenesis in Schistosoma. Excretory System of Schistosomes. Acute Schistosomiasis. Chronic Schistosomiasis. Neuroschistosomiasis: Pathogenesis and Clinical Manifestations. Subtle Morbidity in Schistosomiasis. Diagnostic Tests for Schistosomiasis. Control of Schistosomiasis. Chemotherapy against Schistosomiasis. Schistosomiasis Vaccine Development: the Missing Link. Geospatial Surveillance and Response Systems for Schistosomiasis. Future Directions: The Road to Elimination.
£175.75
Taylor & Francis Inc Robotic Assistive Technologies
Book SynopsisThis book contains a comprehensive overview of all current uses of robots in rehabilitation. The underlying principles in each application are provided. This is followed by a critical review of the technology available, of the utilization protocols, and of user studies, outcomes, and clinical evidence, if existing. Ethical and social implications of robot use are also discussed. The reader will have an in depth view of rehabilitation robots, from principles to practice.Table of ContentsFundamentals of Robot Application, Human Robot Interaction, Robotic Systems to Support Manipulation, Robotic Prosthesis, Robotic Systems to Support Mobility, Robots for Rehabilitation Therapy, Exoskeletons, Robotic Systems to Promote Cognitive Development, Social Robotics-Children with ASD, Social Robotics - Elderly, Personal Assistant Robots, Ethical adn Social Implications.
£123.50
Taylor & Francis Inc DNA Nanoscience
Book SynopsisDNA Nanoscience: From Prebiotic Origins to Emerging Nanotechnology melds two tales of DNA. One is a look at the first 35 years of DNA nanotechnology to better appreciate what lies ahead in this emerging field. The other story looks back 4 billion years to the possible origins of DNA which are shrouded in mystery. The book is divided into three parts comprised of 15 chapters and two Brief Interludes.Part I includes subjects underpinning the book such as a primer on DNA, the broader discipline of nanoscience, and experimental tools used by the principals in the narrative. Part II examines the field of structural DNA nanotechnology, founded by biochemist/crystallographer Nadrian Seeman, that uses DNA as a construction material for nanoscale structures and devices, rather than as a genetic material. Part III looks at the work of physicists Noel Clark and Tommaso Bellini who found that short DNA (nanoDNA) forms liquid crystals that act as a structural gatTrade Review‘DNA Nanoscience takes us on a journey into the future, where sub-microscopic gadgets built from DNA may be used to detect specific molecules one-at-a-time or to deliver therapeutic drugs specifically to cancer cells. Looking in the other direction, the journey takes us back 4 billion years to a time when the self-organization of DNA into liquid crystals may have facilitated the reproduction of what would become our genetic material, arguably the key step in the origin of life.DNA Nanoscience is scholarly and full of technical figures. But the science is accompanied by clear explanations that make it accessible to college student and science-savvy citizens. It is a pleasure to find a book that is so true to the science while being so enjoyable to read.’– Thomas R. CechDistinguished Professor, University of Colorado-Boulder; Director, BioFrontiers Institute; Nobel Laureate (Chemistry 1989).‘Douglas’ DNA Nanoscience is something of a miracle.’– Stuart KauffmanEmeritus Professor Biochemistry and Biophysics, University of Pennsylvania; Affiliate Professor, The Institute for Systems Biology, Seattle; Author of At Home in the Universe.‘This book changed my life. Every seven years, as my sabbatical approaches, I search about for a new direction to focus my research and Ken Douglas’ book, DNA Nanoscience, appeared just in time.’– Seth FradenProfessor of Physics; Director, The Bioinspired Soft Materials Center, Brandeis University.‘Instructive like a textbook and exciting like a novel! For everybody interested in modern natural sciences, this book is a must to read.’– Andreas HerrmannProfessor of Polymer Chemistry and Bioengineering; Chair of the Board, The Zernike Institute for Advanced Materials; University of Groningen, The Netherlands.‘To sum up, this is both a lively and profound book, the reading of which I strongly recommend.’– Jacques ProstDirector Emeritus of CNRS (Le Centre national de la recherche scientifique) at Institut Curie, Paris; Distinguished Professor, National University of Singapore.‘This book tells a fascinating new story about DNA. The subject matter also stretches as needed into biology to teach basic ideas about cell membranes and metabolism. It provides a wonderful taste of DNA nanoscience at the research frontier.’– Arjun G. YodhJames M. Skinner Professor of Science, Endowed Chair; Director, PENN Laboratory for Research on the Structure of Matter, University of Pennsylvania.‘The only way that the general public will continue to trust the proclamation of the scientific establishment is through books like this one – where the foibles and fears and eccentricities of the scientists are shown to be the same as those of the artist, musician and businessman. Scientists are just artists who want to work with mother nature, without the freedom to make up new worlds as we go along. The real world is magical enough for them.’– Joseph A. Zasadzinski3M Harry Heltzer Chair in Multidisciplinary Science and Technology; Chemical Engineering and Materials Science, University of Minnesota.'The book’s eclectic and elaborate vision, looking back to the ancient past and forward to the equally unknowable future sets Douglas’ DNA Nanoscience apart from other attempts to present DNA nanoscience.... Written in beautiful prose and richly illustrated with over 200 full-color figures ... it also serves as a bird’s-eye survey for a more general readership, viz., for those in the public who are curious and enjoy thinking. These citizens are aware of DNA nanoscience snippets making it into the daily news but would like to acquire a deeper, more meaningful and thorough understanding of what the fuss is all about.Douglas’ book DNA Nanoscience: From Prebiotic Origins to Emerging Nanotechnology covers an astoundingly broad ground.... By writing this book on the emerging field of DNA nanoscience Kenneth Douglas has thus done a double service—to science as well as to its public image. I believe that the reception of the book will do justice to the meticulous research and artistry of this tome.'– Rudolf Podgornik (Jožef Stefan Institute)Journal of Biological Physics (August 2016), DOI: 10.1007/s10867-016-9425-4.‘DNA Nanoscience takes us on a journey into the future, where sub-microscopic gadgets built from DNA may be used to detect specific molecules one-at-a-time or to deliver therapeutic drugs specifically to cancer cells. Looking in the other direction, the journey takes us back 4 billion years to a time when the self-organization of DNA into liquid crystals may have facilitated the reproduction of what would become our genetic material, arguably the key step in the origin of life.DNA Nanoscience is scholarly and full of technical figures. But the science is accompanied by clear explanations that make it accessible to college student and science-savvy citizens. It is a pleasure to find a book that is so true to the science while being so enjoyable to read.’– Thomas R. CechDistinguished Professor, University of Colorado-Boulder; Director, BioFrontiers Institute; Nobel Laureate (Chemistry 1989).‘Douglas’ DNA Nanoscience is something of a miracle.’– Stuart KauffmanEmeritus Professor Biochemistry and Biophysics, University of Pennsylvania; Affiliate Professor, The Institute for Systems Biology, Seattle; Author of At Home in the Universe.‘This book changed my life. Every seven years, as my sabbatical approaches, I search about for a new direction to focus my research and Ken Douglas’ book, DNA Nanoscience, appeared just in time.’– Seth FradenProfessor of Physics; Director, The Bioinspired Soft Materials Center, Brandeis University.‘Instructive like a textbook and exciting like a novel! For everybody interested in modern natural sciences, this book is a must to read.’– Andreas HerrmannProfessor of Polymer Chemistry and Bioengineering; Chair of the Board, The Zernike Institute for Advanced Materials; University of Groningen, The Netherlands.‘To sum up, this is both a lively and profound book, the reading of which I strongly recommend.’– Jacques ProstDirector Emeritus of CNRS (Le Centre national de la recherche scientifique) at Institut Curie, Paris; Distinguished Professor, National University of Singapore.‘This book tells a fascinating new story about DNA. The subject matter also stretches as needed into biology to teach basic ideas about cell membranes and metabolism. It provides a wonderful taste of DNA nanoscience at the research frontier.’– Arjun G. YodhJames M. Skinner Professor of Science, Endowed Chair; Director, PENN Laboratory for Research on the Structure of Matter, University of Pennsylvania.‘The only way that the general public will continue to trust the proclamation of the scientific establishment is through books like this one – where the foibles and fears and eccentricities of the scientists are shown to be the same as those of the artist, musician and businessman. Scientists are just artists who want to work with mother nature, without the freedom to make up new worlds as we go along. The real world is magical enough for them.’Joseph A. Zasadzinski3M Harry Heltzer Chair in Multidisciplinary Science and Technology; Chemical Engineering and Materials Science, University of Minnesota.'The book’s eclectic and elaborate vision, looking back to the ancient past and forward to the equally unknowable future sets Douglas’ DNA Nanoscience apart from other attempts to present DNA nanoscience.... Written in beautiful prose and richly illustrated with over 200 full-color figures ... it also serves as a bird’s-eye survey for a more general readership, viz., for those in the public who are curious and enjoy thinking. These citizens are aware of DNA nanoscience snippets making it into the daily news but would like to acquire a deeper, more meaningful and thorough understanding of what the fuss is all about.Douglas’ book DNA Nanoscience: From Prebiotic Origins to Emerging Nanotechnology covers an astoundingly broad ground.... By writing this book on the emerging field of DNA nanoscience Kenneth Douglas has thus done a double service—to science as well as to its public image. I believe that the reception of the book will do justice to the meticulous research and artistry of this tome.'– Rudolf Podgornik (Jožef Stefan Institute)Journal of Biological Physics (August 2016), DOI: 10.1007/s10867-016-9425-4.Table of ContentsA Note to the ReaderPrefaceAuthor BiographyAcknowledgmentsINTRODUCTION: Grandma Needs a WalkerPART I — The Story Line and Its UnderpinningsCHAPTER ONE — Down the Road and the GemischDramatis Personae, Part I: Nadrian SeemanMolecular Crystals—Inspiration from EscherPerspiration and ReinventionDramatis Personae, Part II: Noel Clark, Tommaso BelliniLiquid Crystals and Self-AssemblySeeman, Bellini and Clark, and Base ComplementarityConventional Wisdom and an Alternative ViewEndnotesCHAPTER TWO — DNA: The Molecule That Makes Life Work—and MoreErwin ChargaffRosalind FranklinJames Watson, Francis Crick, and Maurice WilkinsDNA SequencingPolyacrylamide Gel Electrophoresis (PAGE)DNA SynthesisExercises for Chapter TwoEndnotesCHAPTER THREE — Travels to the NanoworldThe Scanning Tunneling Microscope (STM)Moving Atoms With an STMStanding WavesQuantum CorralsNanomethodologySpherical Nucleic Acids (SNAs)Biodiagnostic Detection Using SNAsExercises for Chapter ThreeEndnotesCHAPTER FOUR—Liquid Crystals: Nature’s Delicate Phase of MatterPhase TransitionsClasses of Liquid CrystalsCell Membranes and the Langmuir TroughMicellesLiquid Crystal DisplaysExercises for Chapter FourEndnotesCHAPTER FIVE — Tools of the TradePolarized Light MicroscopyLiquid Crystal Texture Seen Through a Depolarized Light MicroscopeTransmission Electron Microscopy (TEM)Atomic Force Microscopy (AFM)X-Ray Diffraction and Bragg’s LawThe Phase ProblemSynchrotron X-Ray DiffractionExercises for Chapter FiveEndnotesPART II — The Emerging Technology: Nanomaterials Constructed From DNACHAPTER SIX — The Three Pillars of Structural DNA NanotechnologyBranched DNA and DNA JunctionsSticky EndsImmobile Four-Arm DNA JunctionTwo-Dimensional Ligation of DNA JunctionsDeconstruction of Concatenated Nucleic Acid JunctionsMacrocyclesThree-Dimensional Constructions and CatenanesThe DNA CubeExercises for Chapter SixEndnotesCHAPTER SEVEN — Motif Generation, Sequence Design, Nanomechanical DevicesFlexible Junctions ReduxThe Double-Crossover (DX) MoleculeDesign and Self-Assembly of Two-Dimensional DNA CrystalsTwo-Dimensional Nanoparticle ArraysSequence DesignNanomechanical DevicesExercises for Chapter SevenEndnotesCHAPTER EIGHT—DNA Origami, DNA BricksScaffolded DNA OrigamiDNA Origami PatternsStrand Invasion also called Strand DisplacementDNA Origami With Complex Curvatures in Three DimensionsDNA Tiles in Two DimensionsDNA Bricks in Three DimensionsDNA Brick Shapes in Three DimensionsDNA Brick CrystalsSeeman, Rothemund, and YinExercises for Chapter EightEndnotesCHAPTER NINE — DNA Assembly Line and the Triumph of Tensegrity TrianglesDNA Nanoscale Assembly Line (Overview)DNA WalkersDNA Machines and Paranemic Crossover MoleculesDNA Cassette With Robot Arm and DNA Origami TrackDNA Assembly LineThe Triumph of Tensegrity TrianglesExercises for Chapter NineEndnotesBRIEF INTERLUDE I — Back to MethuselahMolecular-Scale WeavingMoors and Crossover MoleculesTensegrity SculptingMayan Pottery, Chirality, and the Handedness of LifeEndnotesCHAPTER TEN — DNA Nanotechnology Meets the Real WorldCell Membrane ChannelsSynthetic Membrane Channels via DNA NanotechnologyCurrent GatingChannels as Single-Molecule SensorsMolecular Nanorobots Built by DNA Origami: Cell-Targeted Drug DeliveryTests of Nanorobot FunctionTest of Binding Discrimination: Healthy Cells vs. Leukemia Cells (NK Cells)Exercises for Chapter TenEndnotesPART III — The Possible Origins of Life’s Information CarrierCHAPTER ELEVEN — Chance FindingsOnsager’s Criterion for an Isotropic-Nematic Liquid Crystal Phase TransitionNanoDNA Seems to Violate Onsager’s Venerable CriterionThe DetailsShifting GearsPhase Separation into Liquid Crystal DropletsThe Depletion InteractionFlory’s ModelExercises for Chapter ElevenEndnotesCHAPTER TWELVE — Unexpected ConsequencesHierarchical Self-AssemblyNanoRNABlunt Ends and Sticky EndsBase Stacking ForcesThe Scope of the Self-Assembly Mechanisms of Nucleic AcidsRandom-Sequence NanoDNAThe Strange World of Random-Sequence NanoDNALiquid Crystal Ordering of Random-Sequence NanoDNANon-Equilibrium Statistical Mechanics: Kinetic Arrest and Nonergodic BehaviorExercises for Chapter TwelveEndnotesCHAPTER THIRTEEN — Ligation: Blest be the Tie That BindsNanoDNA Stacking: Weak Physical Attractive Forces vs. Chemical LigationAbiotic Ligation Experiments with EDCThe Scheme: Polyethylene glycol (PEG)-Induced Phase SeparationGel Electrophoresis of D1p Oligomers With Polyacrylamide and Agarose GelsAnother Stellar Contribution by Chemist Paul J. FloryAnalysis of Gel Profiles: The Experimental Data is Well Described by the Flory ModelThe Lowdown on Ligation EfficiencyThe Liquid Crystal Phase as GatekeeperCascaded Phase SeparationExercises for Chapter ThirteenEndnotesBRIEF INTERLUDE II — The Handedness of LifeChiralityLife is HomochiralMacroscopic Chiral Helical Precession of Molecular OrientationBellini and Clark Examine NanoDNA ChiralityA Lighter Take on ChiralityExercises for Brief Interlude IIEndnotesCHAPTER FOURTEEN — All the World’s a Stage and Life’s a Play—Did it Arise From Clay?Emergence and ComplexityMiller-Urey ExperimentRNA World HypothesisOther Plausible VenuesReplicator-First vs. Metabolism-FirstFeats of ClayThe Lipid WorldLiquid Crystals in the Work of Deamer and the Work of Bellini/ClarkManfred Eigen and Stuart KauffmanExercises for Chapter FourteenEndnotesCHAPTER FIFTEEN — The Passover Question: Why is This Origins Proposal Different From All Other Proposals?Emergence and Broken SymmetryAbout-FaceOccam’s RazorThe RNA World RevisitedSticky Business, Part I: What Constitutes Plausible Prebiotic Conditions?Sticky Business, Part II: The Origins Question—Whose Home Turf Is It?Discovering the Physical Processes that Enabled the Chemistry of LifeMetabolism-First RevisitedComputer Simulations and Mathematical ModelingAn Ancient "Liquid Crystal World"EndnotesEpilogueAPPENDIX — Texture of Liquid Crystal Optical ImagesSmectic Phase Liquid Crystal TextureBent-Core MoleculesExtinction BrushesChiral Nematic Texture of NanoDNA Liquid CrystalsColumnar Texture of NanoDNA Liquid CrystalsEndnotesGlossaryIndex
£65.54
Taylor & Francis Inc Huber and Headricks Handwriting Identification
Book SynopsisForensic document examination is the study of physical evidence and physical evidence cannot lie. Only its interpretation can err. Only the failure to find it, or to hear its true testimony can deprive it of its value.âRoy Huber This is a comprehensive update of Huber and Headrick's seminal work on handwriting examination. New coverage includes a review of forensic handwriting examination research, handwriting analysis training and proficiency, revised methods and procedures, an updated listing and clarification of terminology and electronic signatures, the analysis of digitized handwriting, and other related technological advances. The book includes updated photographs, several added illustrations, and advances in techniques based on the scientific research conducted in the area over the last 20 years.Features of the new edition include: The latest on electronic signatures, digital handwriting, automated handwriting verification, and the many advances in tTable of ContentsIntroduction. The World of Documents. 1. History of Forensic Document Examination 2. The Development of Handwriting 3. The Discrimination of Handwriting 4. Premises for the Identification of Handwriting 5. Fundamentals of the Identification Process 6. Discrimination and Identification of Handwriting 7. Special Problems in the Discrimination and Identification of Writing 8. Extrinsic Factors Influencing Handwriting 9. Intrinsic Factors Influencing Handwriting 10. Requirements and Results 11. The Diagnosis of Handwriting Identification 12. Handwriting, Document Analysis, and Electronic Media 13. Evaluating Document Examiner Competency 14. Science and Handwriting Identification 15. Terminology References Appendix A
£115.00
Taylor & Francis Inc Essentials of Polygraph and Polygraph Testing
Book SynopsisThroughout history, there has been an intrinsic need for humans to detect deception in other humans. Developed in 1923, the polygraph machine was a tool designed to do just this. To date, there have been many improvements made to the basic polygraph instrument. This book outlines the instrumentation as well as the latest in questioning techniques and methods available to the professional interviewer to determine truth from deception. The book covers psychology and physiology, a history of polygraph with the advances of leading figures, question formulation, data analysis, legal implications and legal cases, and the author's developed technique Integrated Zone Comparison Technique (IZCT).Table of ContentsPolygraph History. Question Formulation. Technique Development. Integrated Zone Comparison Technique (IZCT). The Pre-Test Interview. Data Analysis. Pre-Employment Testing. Report Writing. Legal Cases. Ethics and Standards. Research.
£135.00
Taylor & Francis Inc Handbook of MetalMicrobe Interactions and
Book SynopsisAround the World, metal pollution is a major problem. Conventional practices of toxic metal removal can be ineffective and/or expensive, delaying and exacerbating the crisis. Those communities dealing with contamination must be aware of the fundamentals advances of microbe-mediated metal removal practices because these methods can be easily used and require less remedial intervention. This book describes innovations and efficient applications for metal bioremediation for environments polluted by metal contaminates.Table of ContentsIntroduction to metal contamination and Environmental Issues. Metals and their toxic effects: An introduction to the noxious elements. Sources of metal pollution, global status and conventional remediation practices. Microbes: The natural scavengers and their role in metal bioremediation. Havocs of toxic metal contaminations: unforgettable stories. Metal-microbe interactions. Evolution of inherent biochemical pathways in microorganisms in metal contaminated environments. Enzyme catalysed microbial transformations of metals. Cellular and genetic machineries of metal resistance in microbes (the role of plasmids, genomic DNA, transposons and other genetic elements). Biosorption of metals by microorganism: bacteria, fungi, algae, actinobacteria. Metal binding proteins and peptides and their role in bioremediation. Bacterial exopolysaccharides in metal removal. Molecular approaches in metal bioremediation. Genetic engineering for enhanced metal remediation by microbes. Novel metabolic pathways for toxic metal removal from the contaminated environment. Introduction of heterologous microbial Metallothioneins into transgenic plants for metal removal. Genetically modified biosorbents for toxic metal removal. GMOs in natural environment and strategies to increase their survivability and stability. Bacterial biofilm and genetic regulation in metal detoxification. Interdisciplinary approaches for enhanced metal bioremediation. Interaction between metals, microbes and plants. Immobilization techniques for bioremediation of metals. Bioreactor based approaches of toxic metal removal. Computer aided studies in metal bioremediation. Bacterial mediated nanoparticle synthesis and their role in bioremediation. Specific metal bioremediation Studies. Investigation on arsenic accumulating and transforming bacteria for potential use in bioremediation. Elucidation of cadmium resistance gene in Cadmium resistant bacteria for utilization in bioremediation. Bioremediation of copper present in waste water using copper resistant microorganisms. Bioremediation of mercury and importance of bacterial mer genes: A biotechnology approach. Suitability of nickel resistant microbes for the use in enhanced nickel bioremediation. Efficacy of microbial entities with lead resistant genotype for in-situ bioremediation of lead contaminated sites. Zinc biosorption and subsequent mineralization/transformation by the microbial species for bioremediation of zinc. Bioremediation of chromium solutions and chromium containing waste waters. Harnessing radiation inducible promoter and gene clusters of microorganisms for enhanced precipitation of radioactive waste. Assessment of diversity and bioremediation potential of mercury resistant marine bacteria in Bay of Bengal, Odisha, India.
£247.00
Taylor & Francis Inc Metabolic Regulation and Metabolic Engineering
Book SynopsisThe global warming problem is becoming critical year by year, causing climate disaster all over the world, where it has been believed that the CO2 gas emitted from the factories and the burning of fossil fuels may be one of the reasons of global warming. Moreover, the global stock of fossil fuels is limited, and may run out soon within several tens of years. Although wind, geo-thermal, and tide energies have been considered as clean energy sources, those depend on the land or sea locations and subject to the climate change. Biofuel and biochemical production from renewable bio-resources has thus been paid recent attention from environmental protection and energy production points of view, where the current chemical and energy producing plants can be also utilized with slight modification. The so-called 1st generation biofuels have been produced from corn starch and sugarcane in particular in USA and Brazil. However, this causes the problem of the Table of ContentsBackground. Pretreatment of biomass. Transport of nutrients and carbon catabolite repression for the selective carbon sources. Catabolite regulation of the main metabolism. Metabolic regulation in response to growth environment. Metabolic engineering for the production of a variety of biofuels and biochemical. Biofuel and biochemical production by photosynthetic organisms. Systems biology approach and modeling. References. Appendix A.
£175.75
Taylor & Francis Inc Computational Exome and Genome Analysis
Book SynopsisExome and genome sequencing are revolutionizing medical research and diagnostics, but the computational analysis of the data has become an extremely heterogeneous and often challenging area of bioinformatics. Computational Exome and Genome Analysis provides a practical introduction to all of the major areas in the field, enabling readers to develop a comprehensive understanding of the sequencing process and the entire computational analysis pipeline.Trade Review"This book represents a timely contribution to the burgeoning field of exome and genome sequencing data analysis. It covers all pertinent topics ranging from raw data quality control to medical interpretation of genetic mutations, with detailed command line examples as well as in-depth explanations on every step of analysis. Highly recommended to any researchers, scientists, clinicians or students who are interested to learn practical skills on genome analysis."-Kai Wang, Department of Biomedical Informatics, Columbia University"This book provides a very comprehensive overview of all the fundamentals that are needed to work as a bioinformatician in the field of exome and genome analysis. All of the important processing steps are illustrated with practical examples and code. In addition, the casual writing style makes this book an easy read."-Christian Gilissen, Department of Human Genetics, Radbound Univeristy Medical Center "This book is an excellent example of a hybrid between a textbook and an up-to-date research reference on the latest bioinformatics tools available in this eld. Its rigorous and thorough approach makes it a reliable starting point for bioinformaticians and biologists. By including details on methodological aspects of some of the algorithms used for various components of the data analysis and coupling these with fully-commented examples and exercises, this book presents itself as a must-have for novices and experts alike. Given the fast pace of the field, no book can be exhaustive, however, the wide variety of tools presented here recommend it to a wide audience, both as expertise and focused research interests."-Irina Ioana Mohorianu, Zentralblatt MATH"This book represents a timely contribution to the burgeoning field of exome and genome sequencing data analysis. It covers all pertinent topics ranging from raw data quality control to medical interpretation of genetic mutations, with detailed command line examples as well as in-depth explanations on every step of analysis. Highly recommended to any researchers, scientists, clinicians or students who are interested to learn practical skills on genome analysis."-Kai Wang, Department of Biomedical Informatics, Columbia University"This book provides a very comprehensive overview of all the fundamentals that are needed to work as a bioinformatician in the field of exome and genome analysis. All of the important processing steps are illustrated with practical examples and code. In addition, the casual writing style makes this book an easy read."-Christian Gilissen, Department of Human Genetics, Radbound Univeristy Medical Center "This book is an excellent example of a hybrid between a textbook and an up-to-date research reference on the latest bioinformatics tools available in this eld. Its rigorous and thorough approach makes it a reliable starting point for bioinformaticians and biologists. By including details on methodological aspects of some of the algorithms used for various components of the data analysis and coupling these with fully-commented examples and exercises, this book presents itself as a must-have for novices and experts alike. Given the fast pace of the field, no book can be exhaustive, however, the wide variety of tools presented here recommend it to a wide audience, both as expertise and focused research interests."-Irina Ioana Mohorianu, Zentralblatt MATHTable of ContentsIntroduction. Whole Exome and Genome Sequencing. NGS Technology. Illumina Technology. Obtaining WES/WGS Data for this book. Raw Data Processing. FASTQ Format. Raw Data: Quality Control. Trimming. Alignment. Alignment: Mapping reads to the reference genome. SAM/BAM Format. Postprocessing the Alignment. Alignment Data: Quality control. Variant Calling. Variant Calling & Quality-based Filtering. Variant Call Format. Jannovar. Variant Annotation. Variant Calling: Quality Control. Integrative Genomics Viewer (IGV): Visualizing Alignments and Variants. De novo variants. Structural variation. Variant Filtering. Pedigree and Linkage Analysis. Intersection Analysis and Rare Variant Association Studies. Variant Frequency Analysis. Variant Pathogenicity Prediction. Prioritization. Variant Prioritization. Prioritization by Random Walk Analysis. Phenotype Analysis. Exomiser and Geniomiser. Medical Interpretation. Cancer. A (Very) Short Introduction to Cancer. Somantic variants in cancer. Tumor Evolution and Sample Purity. Driver Mutations and mutational signatures.
£123.50
Hodder Education CCEA AS/A2 Unit 3 Biology Student Guide:
Book SynopsisEnsure your students get to grips with the practical and skills needed to succeed at AS and A Level Biology. With an in-depth assessment-driven approach that builds and reinforces understanding; clear summaries of practical work with sample questions and answers help to improve exam technique in order to achieve higher grades.Written by experienced teacher John Campton, this Student Guide for practical Biology:- Help students easily identify what they need to know with a concise summary of practical work examined in the A-level specifications.- Consolidate understanding of practical work, methodology, mathematical and other skills out of the laboratory with exam tips and knowledge check questions, with answers in the back of the book.- Provide plenty of opportunities for students to improve exam technique with sample answers, examiners tips and exam-style questions. - Offer support beyond the Student books with coverage of methodologies and generic practical skills not focused on in the textbooks.
£14.10
Hodder Education Pearson Edexcel A-level Biology
Book SynopsisGet to grips with the core practicals and develop the skills students need to succeed with an assessment-driven approach, combining clear summaries of practical work that reinforce understanding, with sample questions and answers to improve exam technique. - Easily identify what students need to know with a concise summary of the required practical work examined in the A-level specifications. - Consolidate understanding of practical work, methodology, mathematical and other skills out of the laboratory with exam tips and knowledge check questions, with answers in the back of the book. - Improve exam technique with sample answers, examiner's tips and exam-style questions. - Provide extra support with coverage of methodologies and generic practical skills not focused on in the textbooks.
£15.48
Forgotten Books The Romance of the Earth (Classic Reprint)
£19.69
Forgotten Books Curing and Fermentation of Cigar Leaf Tobacco (Classic Reprint)
£24.48
Rowman & Littlefield Thinking Race: Social Myths and Biological
Book SynopsisThinking Race argues that racism results from a misguided blending of biological facts with pernicious socially constructed ideas. This book aims to help readers accept the reality of human difference while understanding human unity. The esteemed author team of Richard A. Goldsby, a biologist, and Mary Catherine Bateson, an anthropologist, recognize race as primarily socially constructed but also having biological reality. They argue that misunderstanding the nature of race stands in the way of addressing and solving the problems of our current racial climate. The book addresses controversial subjects, exploring whether or not race-associated biological differences are differences that might impact mental ability, medical practice, or athletic performance. Because the black/white divide is a dominant and continuing theme of U.S. history and culture, the book devotes a good deal of attention to these groups, while also covering Native Americans and Asian Americans. Thinking Race provides a thoughtful and nuanced case for viewing race as a cultural play in an ancestral theater. This perspective, anthropological and biological, will build a framework for thinking about race and provide conceptual tools for better understanding and addressing this charged and often pernicious notion.Trade ReviewIs race a social construction or a biological reality? In this brave and necessary book, Richard Goldsby and Mary Catherine Bateson provide a persuasive response: it is both. Using a wealth of genetic and cultural evidence, Goldsby and Bateson shed light on a question too often dominated by heat, and they explore the implications of their answer for medicine, social policy, and politics. -- William A. Galston, Senior Fellow, The Brookings InstitutionThis scholarly, but completely accessible and entertaining, treatise examines what we term “race” providing food for serious thought on several levels. The authors bring expertise from their respective areas of scholarship to bear on this complex topical issue. Their discussion of the intricacies involved, not readily resolved by current DNA analyses or dissection of cultural issues, gives new and thoughtful insight. Having defined race in a reasonable way next are enumerated consequences of racial discrimination along with some suggestions to balance inequity. An open-minded reading of this treatment may require rethinking of common stereotypes and abandoning racist attitudes. -- Thomas J. Kindt, authorThis wise book by a distinguished biologist and an acclaimed anthropologist forthrightly, clearly, and concisely summarizes the objective evidence that there are races and racial differences: readers will find some surprising. The authors’ take bears on many `hot-button’ issues and provides compelling and reasoned insight into how society and culture, not biology, determines racial inequality. Thinking Race is a must read. -- Lydia Villa-Komaroff, independent consultant, Intersections: Science, Business, Diversity; former vice president of research, Northwestern UniversityIf we are ever to move beyond the racial divisiveness that continues to plaque our nation, we must have courageous conversations about race. Goldsby and Bateson have written an important and engaging book that can enlighten these conversations in the interest of social justice. By explaining the biology of race, and how race is largely socially constructed, the authors help us accept human differences among us at the same time that we understand the power of human unity. -- Johnnetta Betsch Cole, President Emerita of Spelman College and Bennett College for WomenThe authors draw upon a wide spectrum of sources and methods in crafting a compelling argument that distinguishes and illustrates the complexities between race as a biological concept and race as a social construct. -- Robert Wedgeworth, founding President and CEO of ProLiteracy WorldwideTable of ContentsPreface Acknowledgments 1 Generations of Migration 2 The Notion and Nature of Race 3 Human Diversity 4 Race and Medicine 5 Race and Ability 6 Seeking Solutions Suggested Readings for Thinking Race Index
£37.11
Little, Brown & Company Flush: The Remarkable Science of an Unlikely
Book SynopsisFor readers of Giulia Enders' Gut and Bill Bryson's The Body, a surprising, witty and sparkling exploration of the teeming microbiome of possibility in human feces from microbiologist and science journalist Bryn Nelson.The future is sh*t: the literal kind. For most of human history we've been, well, disinclined to take a closer look at our body's natural product-the complex antihero of this story-save for gleaning some prophecy of our own health. But if we were to take more than a passing look at our poop, we would spy a veritable cornucopia of possibilities. We would see potent medicine, sustainable power, and natural fertilizer to restore the world's depleted lands. We would spy a time capsule of evidence for understanding past lives and murderous ends. We would glimpse effective ways of measuring and improving human health from the cradle to the grave, early warnings of community outbreaks like Covid-19, and new means of identifying environmental harm-and then reversing it.Flush is both an urgent exploration of the world's single most squandered natural resource, and a cri de coeur (or cri de colon?) for the vast, hidden value in our "waste." Award-winning journalist and microbiologist Bryn Nelson, PhD, leads readers through the colon and beyond with infectious enthusiasm, helping to usher in a necessary mental shift that could restore our balance with the rest of the planet and save us from ourselves. Unlocking poop's enormous potential will require us to overcome our shame and disgust and embrace our role as the producers and architects of a more circular economy in which lowly byproducts become our species' salvation. Locked within you is a medicine cabinet, a biogas pipeline, a glass of drinking water, a mound of fuel briquettes; it's time to open the doors (carefully!). A dose of medicine, a glass of water, a gallon of rocket fuel, an acre of soil: sometimes hope arrives in surprising packages.
£16.14
Little, Brown & Company Flush: The Remarkable Science of an Unlikely
Book SynopsisThe future is sh*t: the literal kind. For most of human history we've been, well, disinclined to take a closer look at our body's natural product-the complex antihero of this story-save for gleaning some prophecy of our own health. But if we were to take more than a passing look at our poop, we would spy a veritable cornucopia of possibilities. We would see potent medicine, sustainable power, and natural fertilizer to restore the world's depleted lands. We would spy a time capsule of evidence for understanding past lives and murderous ends. We would glimpse effective ways of measuring and improving human health from the cradle to the grave, early warnings of community outbreaks like Covid-19, and new means of identifying environmental harm-and then reversing it.Flush is both an urgent exploration of the world's single most squandered natural resource, and a cri de coeur (or cri de colon?) for the vast, hidden value in our "waste." Award-winning journalist and microbiologist Bryn Nelson, PhD, leads readers through the colon and beyond with infectious enthusiasm, helping to usher in a necessary mental shift that could restore our balance with the rest of the planet and save us from ourselves. Unlocking poop's enormous potential will require us to overcome our shame and disgust and embrace our role as the producers and architects of a more circular economy in which lowly byproducts become our species' salvation. Locked within you is a medicine cabinet, a biogas pipeline, a glass of drinking water, a mound of fuel briquettes; it's time to open the doors (carefully!). A dose of medicine, a glass of water, a gallon of rocket fuel, an acre of soil: sometimes hope arrives in surprising packages.
£22.50
Basic Books The Story Paradox: How Our Love of Storytelling
Book SynopsisHumans are storytelling animals. Stories are what make our societies possible. Countless books celebrate their virtues. But Jonathan Gottschall, an expert on the science of stories, argues that there is a dark side to storytelling we can no longer ignore. Storytelling, the very tradition that built human civilization, may be the thing that destroys it.In The Story Paradox, Gottschall explores how a broad consortium of psychologists, communications specialists, neuroscientists, and literary quants are using the scientific method to study how stories affect our brains. The results challenge the idea that storytelling is an obvious force for good in human life. Yes, storytelling can bind groups together, but it is also the main force dragging people apart. And it's the best method we've ever devised for manipulating each other by circumventing rational thought. Behind all civilization's greatest ills-environmental destruction, runaway demagogues, warfare-you will always find the same master factor: a mind-disordering story.Gottschall argues that societies succeed or fail depending on how they manage these tensions. And it has only become harder, as new technologies that amplify the effects of disinformation campaigns, conspiracy theories, and fake news make separating fact from fiction nearly impossible.With clarity and conviction, Gottschall reveals why our biggest asset has become our greatest threat, and what, if anything, can be done. It is a call to stop asking, "How we can change the world through stories?" and start asking, "How can we save the world from stories?"
£20.90
