Description
Book SynopsisMiniaturization in the fields of chemistry and molecular biology has resulted in the lab-on-a-chip. Such systems are micro-fabricated devices capable of handling extremely small fluid volumes facilitating the scaling of single or multiple lab processes down to a microchip-sized format. The convergence of lab-on-a-chip technology with the field of cell biology facilitated the development of organ-on-a-chip systems. Such systems simulate the function of tissues and organs, having the potential to bypass some cell and animal testing methods. These technologies have generated high interest as applications for disease modeling and drug discovery.
This book, edited by Drs. Sean Murphy and Anthony Atala, provides a comprehensive coverage of the technologies that have been used to develop organ-on-a-chip systems. Known leaders cover the basics to the most relevant and novel topics in the field, including micro-fabrication, 3D bio-printing, 3D cell culture techniques, biosensor design
Table of Contents
Introduction. Microfabrication and 3D Bioprinting. 3D Cell Culture/Tissue Spheroids. Biosensors and Microelectronics. Microfluidics. Big Data/Predictive Analysis. Lab-on-a-Chip. Lung-on-a-Chip. Liver-on-a-Chip. Heart-on-a-Chip. Skin-on-a-Chip. Kidney-on-a-Chip. Body-on-a-Chip. Liver Cancer-on-a-Chip. Lung Cancer-on-a-Chip. Breast Cancer-on-a-Chip. Cancer Metastasis-on-a-Chip. Cancer Microenvironment-on-a-Chip. Disease Modeling. Toxicology Testing. Detection of Bioweapon Pathogens. Personalized Medicine.
