Biochemistry Books

2147 products


  • Organic Chemistry

    Oxford University Press Organic Chemistry

    2 in stock

    Book SynopsisOrganic chemistry is the chemistry of compounds of carbon. The ability of carbon to link together to form long chain molecules and ring compounds as well as bonding with many other elements has led to a vast array of organic compounds. These compounds are central to life, forming the basis for organic molecules such as nucleic acids, proteins, carbohydrates, and lipids. In this Very Short Introduction Graham Patrick covers the whole range of organic compounds and their roles. Beginning with the structures and properties of the basic groups of organic compounds, he goes on to consider organic compounds in the areas of pharmaceuticals, polymers, food and drink, petrochemicals, and nanotechnology. He looks at how new materials, in particular the single layer form of carbon called graphene, are opening up exciting new possibilities for applications, and discusses the particular challenges of working with carbon compounds, many of which are colourless. Patrick also discusses techniques used in the field.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.Table of ContentsREFERENCES; FURTHER READING; INDEX

    2 in stock

    £9.49

  • A Taste for Poison Eleven deadly substances and

    HarperCollins Publishers A Taste for Poison Eleven deadly substances and

    3 in stock

    Book Synopsis'Indecently entertaining.' A Daily Mail Book of the WeekAn Amazon US Best Book of 2022''A fascinating tale of poisons and poisonous deeds which both educates and entertains.'' Kathy ReichsAs any reader of murder mysteries can tell you, poison is one of the most enduring and popular weapons of choice for a scheming murderer. It can be slipped into a drink, smeared onto the tip of an arrow or the handle of a door, even filtered through the air we breathe. But how exactly do these poisons work to break our bodies down, and what can we learn from the damage they inflict?In a fascinating blend of popular science, medical history, and narrative crime nonfiction, Dr Neil Bradbury explores this most morbidly captivating method of murder from a cellular level. Alongside real-life accounts of murderers and their crimes some notorious, some forgotten, some still unsolved are the equally compelling stories of the poisons involved: eleven molecules of death that work their way through the humanTrade Review‘This very splendid book is essentially a detailed primer on how to dispose of your enemies. … A winning mixture of hard science and true crime stories, is almost indecently entertaining.’ Daily Mail ‘Lively … Bradbury is an engaging, cheerful tour guide.’ New York Times Book Review ‘Captivating in its storytelling and just enough science for the geeks. A tremendously entertaining dip into the dark and compelling world of death.’ Professor Dame Sue Black, author of All That Remains: A Life in Death ‘We’ve all seen Colonel Mustard dead in the library from poisoning. Instead of telling us why, in this original and invigorating book, Neil Bradbury focuses on how, exploring the workings of crime from a scientific basis. Fascinating.’ Judith Flanders, author of The Invention of Murder 'Neil Bradbury writes with wit, flair, and authority.' Lindsey Fitzharris, bestselling author of The Butchering Art ‘An engrossing history of poisons, poisonings and poisoners. Alongside the very human stories of the people who fall victim to these deadly substances, it’s packed with quirky detail and easily digestible (pun intended) science.’ Kate Morgan, author of Murder: The Biography 'Weaves jaw-dropping true stories and spellbinding histories behind the most infamous poisons.' Lydia Kang, bestselling author of Quackery: A Brief History of the Worst Ways to Cure Everything 'An unselfconsciously jaunty work of horror. Its stories may leave you eyeing your housemates and sniffing your coffee.' Judy Melinek, M.D. and T.J. Mitchell, bestselling authors of Working Stiff ‘An accessible and fascinating study.’ Publishers Weekly starred review ‘Appealing to any true crime fan … genre-bending.’ Booklist ‘A frightening romp … fascinating, edifying, and terrifying.’ Library Journal

    3 in stock

    £10.44

  • Introduction to Research in the Health Sciences

    Elsevier Health Sciences Introduction to Research in the Health Sciences

    3 in stock

    Book SynopsisTable of Contents Section 1 Methodological foundations of health research 1 Foundations of health research 2 Quantitative and qualitative methods 3 The research process Section 2 Research planning 4 The formulation of research questions 5 Sampling methods and external validity 6 Ethics Section 3 Research designs 7 Experimental designs and randomized controlled trials 8 Surveys and quasi-experimental designs 9 Qualitative research Section 4 Data collection 10 Questionnaires and survey design 11 Mixed methods 12 Interviewing techniques 13 Measurement and observation Section 5 Descriptive statistics 14 Organization and presentation of data 15 Measures of central tendency and variability 16 Standard scores and normal distributions 17 Correlation Section 6 Data analysis and inference 18 Probability and confidence intervals 19 Hypothesis testing: selection and use of statistical tests 20 Effect size and the interpretation of evidence 21 Qualitative data analysis 22 Critical evaluation of published research Section 7 Evaluation and dissemination of research results 23 Synthesis of research evidence: systematic reviews and meta-analyses 24 Translational research

    3 in stock

    £36.99

  • The Chemistry Of Food And Nutrition

    Double 9 Books The Chemistry Of Food And Nutrition

    3 in stock

    Book Synopsis

    3 in stock

    £10.44

  • Biochemistry and Molecular Biology

    Oxford University Press Biochemistry and Molecular Biology

    3 in stock

    Book SynopsisNow in its sixth edition, Biochemistry and Molecular Biology provides the perfect balance between detail and conceptual understanding. Maintaining the much-praised clarity of previous editions, this edition incorporates both new techniques and pivotal discoveries in a succinct, easy-to-digest way, using updated figures and diagrams to help explain complex processes.Updated content on the manipulation of DNA and genes reflects the rapid introduction of new methods in contemporary research, and incorporates up-to-date discussions of recent developments such as gene editing. Chapter summaries are logically laid out, forming bulleted lists which provide students with a consolidation of difficult concepts and progressively guide them through the specifics whilst keeping the big picture in mind. Additional ''find out more'' sections provide helpful problem-solving support and the further reading is divided into types to cater for broader learning needs.With an integrated approach covering boTrade ReviewEasy to read with good use of simple figures and plenty of internal cross-references to other chapters or relevant pages. I was impressed with the inclusion of some very up to date findings. * Dr Peter Morris, School of Life Sciences, Heriot-Watt University *I don't know of any other biology/biochemistry book that explains DNA replication as well as this one. * Lynn Rogers, School of Molecular and Biomedical Science, Adelaide University *The style is very clear, logical and systematic. The diagrams complement the text well. * Dr Momna Hejmadi, Department of Biology and Biochemistry, University of Bath *Good entry level biochemistry textbook that gives students an overview of the diversity of biochemistry and that introduces abstract concepts in a well-explained and accessible way. * Dirk Wildeboer, Natural Sciences, Middlesex University *This textbook presents classical biochemistry material with a balanced emphasis on details and conceptual understanding. Explanations are given in a conversational manner so that students are not distracted by an over-whelming amount of new terminology. * Amanda Storm, Biology, James Madison University *Table of ContentsPart 1: Basic concepts of life 1: The basic molecular themes of life 2: Cells and viruses 3: Energy considerations in biochemistryPart 2: Structure and function of proteins and membranes 4: The structure of proteins 5: Methods in protein investigation 6: Enzymes 7: The cell membrane and membrane proteins 8: Muscle contraction, the cytoskeleton, and molecular motorsPart 3: Metabolism and nutrition 9: General principles of nutrition 10: Food digestion, absorption and distribution to the tissues 11: The storage fuels: Mechanisms of transport, storage, and mobilization of carbohydrate and fat 12: Principles of energy release from food 13: Glycolysis, the TCA cycle, and the electron transport system 14: Energy release from fat 15: An alternative pathway of glucose oxidation: The pentose phosphate pathway 16: Synthesis of glucose (gluconeogenesis) 17: Synthesis of fat and related compounds 18: Nitrogen metabolism: amino acid metabolism 19: Nitrogen metabolism: nucleotide metabolism 20: Mechanisms of metabolic control and their applications to metabolic integration 21: Raising electrons of water back up the energy scale: photosynthesisPart 4: Information storage and utilization 22: The genome 23: DNA synthesis, repair and recombination 24: Gene transcription 25: Protein synthesis and controlled protein breakdown 26: Control of gene expression 27: Protein sorting and delivery 28: Manipulating DNA and genesPart 5: Cells and tissues 29: Cell signalling 30: The cell cycle, cell division, cell death and cancerPart 6: Protective mechanisms against disease 31: Blood clotting, xenobiotic metabolism, and reactive oxygen species 32: The immune system

    3 in stock

    £55.09

  • Infection  Immunity

    Oxford University Press Infection Immunity

    2 in stock

    Book SynopsisGives a perfectly balanced overview of the field, describing the key infectious agents our bodies encounter and how our immune system responds to them. It also explains how diseases are spread and what measures we can take to control this spread, from vaccination to increasing public awareness.Trade ReviewInfectious disease affects everyone. If you are hoping to understand the mechanism of infections and immunity at an introductory level, then you will find this an excellent reference book: my copy is well thumbed and already sports a forest of bookmarks. * Susan Omar, The Biologist *Table of ContentsTHE INFECTIOUS ORGANISMS; THE IMMUNE SYSTEM; THE HOST-PATHOGEN BALANCE

    2 in stock

    £52.99

  • Principles of Toxicology

    CRC Press Principles of Toxicology

    3 in stock

    Book SynopsisReflecting the broad and interdisciplinary nature of toxicology, this third edition of Principles of Toxicology explores the biochemical, physiological, and environmental aspects of the subject.This new edition is updated and revised to include reference to several major new directions in the science of toxicology, including significant changes in thinking about cancer and carcinogenesis as well as the rapid expansion of toxicogenomics. The book also includes new chapters on topics of timely interest such as radiation, food safety, and natural toxins.As in previous editions, chapters combine background material in the appropriate disciplineâwhich helps readers review and remember the basicsâwith new information on toxicology to stress key principles and concepts. Also included is a selection of updated case studies through which principles and concepts are applied to real-world issues. The book features an extensive cross-referencing system linking all seTrade Review"Well-targeted by the authors for the intended purpose. Online access to material is employed where appropriate… Where relevant the text includes historical examples to assist or amplify the subject matter… One of the strengths of the book is the considerable cross referencing which provides useful assistance to the user to fully understand the wider ramifications of what might at first sight appear relatively isolated or limited problems. Furthermore the case-studies achieve exactly what they are intended to do, namely highlight the important points and place them in a context which is relevant and illustrative" - (Highly Commended, Public Health, BMA Medical Book Awards 2016)Table of ContentsMeasuring Toxicity and Assessing Risk. Toxicokinetics. Biotransformation. Cellular Sites of Action. Genomics and New Genetics in Toxicology. Carcinogenesis. Reproductive Toxicology and Teratology. Respiratory Toxicology. Cardiovascular Toxicology. Neurotoxicology. Hepatic Toxicology. Renal Toxicology. Immunotoxicology. Ecological Toxicology. Applications: Pharmacology and Toxicology. Applications: Forensic Toxicology. Applications: Environmental Toxicology and Pollution. Applications: Radiation. Applications: Food Safety. Applications: Toxins. Appendix: List of Selected Toxicants. Index.

    3 in stock

    £94.72

  • Lehninger Principles of Biochemistry

    Macmillan Learning Lehninger Principles of Biochemistry

    15 in stock

    Book Synopsis

    15 in stock

    £71.24

  • A Dictionary of Biomedicine

    Oxford University Press A Dictionary of Biomedicine

    1 in stock

    Book SynopsisThis dictionary includes 10,000 A-Z entries on all areas of biomedicine. It also covers terms from related areas, including anatomy, genetics, pathology, pharmacology, and clinical medicine. Fully cross-referenced and with web links, this is a clear and authoritative guide to an increasingly important area of medicine.Table of ContentsPREFACE; A NOTE ON CONVENTIONS; LISTING OF NAVIGATIONAL ENTRIES; A DICTIONARY OF BIOMEDICINE; APPENDIX 1: THE GREEK ALPHABET; APPENDIX 2: SI UNITS; APPENDIX 3: SINGLE-LETTER CODES FOR AMINO ACIDS

    1 in stock

    £15.74

  • Wilson and Walkers Principles and Techniques of

    Cambridge University Press Wilson and Walkers Principles and Techniques of

    2 in stock

    Book SynopsisBringing this best-selling textbook right up to date, the new edition uniquely integrates the theories and methods that drive the fields of biology, biotechnology and medicine, comprehensively covering both the techniques students will encounter in lab classes and those that underpin current key advances and discoveries. The contents have been updated to include both traditional and cutting-edge techniques most commonly used in current life science research. Emphasis is placed on understanding the theory behind the techniques, as well as analysis of the resulting data. New chapters cover proteomics, genomics, metabolomics, and bioinformatics, as well as data analysis and visualisation. Using accessible language to describe concepts and methods, and with a wealth of new in-text worked examples to challenge students'' understanding, this textbook provides an essential guide to the key techniques used in current bioscience research.Trade Review'After seven editions between 1975 and 2010 this essential textbook has undergone a major update. The new editors, Drs Hofmann and Clokie, recruited many experts to revise individual chapters and added a significant amount of new material, thus making the book even more valuable. This eighth edition is basically a new book that covers the techniques of biochemistry and molecular biology in a very comprehensive manner - it does not go into great detail, but gives the reader a good introduction to all of them. Each chapter contains suggestions for further reading for those in need of a follow-up. Excellent diagrams and illustrations provide help in comprehension of the presented material. Since this text is largely aimed at undergraduate students, it fulfils its role extremely well.' Alexander Wlodawer, National Cancer Institute at FrederickReview from previous edition: 'This book deserves a place in any modern pathology department and brings together a body of information which is traditionally scattered across several texts … it also represents excellent value for money.' Annals of Clinical BiochemistryReview from previous edition: 'It is necessary to have a practical up to date guide to experimental techniques at hand in a laboratory. This book belongs to such kind of texts. It covers all branches of basic as well as advanced techniques. The book represents a fundamental guidebook for work in a laboratory.' PhotosyntheticaReview from previous edition: 'The book is well illustrated, indexed, free of errors and most chapters have problem sets with worked answers. The book is written for 'all bioscience undergraduate students and pre-medical students for whom practical biochemistry, molecular biology and immunology form part of the syllabus' … it is a very good supplement for undergraduate courses in general biochemistry or a text for courses in biochemical techniques. [This book] is also recommended for graduate students and other researchers in applied sciences such as food biochemistry.' Journal of Food BiochemistryReview from previous edition: '… well-written and comprehensive … what truly distinguishes this text from others of its kind are the outstanding chapters on proteins, mass spectrometry and spectroscopic techniques. … a valuable resource for undergraduate or graduate students taking introductory or advanced techniques/laboratory courses in cell/molecular biology, biochemistry or biotechnology.' Microbiology TodayReview from previous edition: 'I found this volume remarkably satisfying in that it answered all those 'why do you do it like this?' type questions. … This book has already received extensive reference value on my bookshelf.' Journal of Biological EducationTable of ContentsForeword Keith Wilson and John Walker; Preface Samuel Clokie and Andreas Hofmann; Tables and resources Andreas Hofmann; 1. Life science studies Samuel Clokie and Andreas Hofmann; 2. Basic principles Parisa Amani and Andreas Hofmann; 3. Cell culture techniques Anwar Baydoun; 4. Recombinant DNA techniques and molecular cloning Ralph Rapley; 5. Preparative biochemistry Samuel Clokie; 6. Electrophoresis Ralph Rapley; 7. Immunochemical techniques Katja Fischer; 8. Flow cytometry John Grainger and Joanne Konkel; 9. Radioisotope techniques Robert Slater; 10. Clinical biochemistry Gillian Rumsby; 11. Microscopy Stephen Paddock; 12. Centrifugation Kay Ohlendieck and Stephen Harding; 13. Spectroscopic techniques Anne Simon and Andreas Hofmann; 14. Basic techniques probing molecular structure and interactions Anne Simon and Joanne Macdonald; 15. Mass spectrometric techniques Sonja Hess and James MacRae; 16. Fundamentals of bioinformatics Cinzia Cantacessi and Anna Protasio; 17. Fundamentals of cheminformatics Paul Taylor; 18. The Python programming language Timothy Stevens; 19. Processing and visualisation of experimental data Jean-Baptiste Cazier; 20. Fundamental genome sequencing and annotation Pasi Korhonen and Robin Gasser; 21. Fundamentals of proteomics Sonja Hess and Michael Weiss; 22. Fundamentals of metabolomics James MacRae; 23. Enzymes and receptors Megan Cross and Andreas Hofmann; 24. Drug discovery and development David Camp.

    2 in stock

    £41.79

  • Biocatalysis in Organic Synthesis: The

    Royal Society of Chemistry Biocatalysis in Organic Synthesis: The

    2 in stock

    Book SynopsisThe application of biocatalysis in organic synthesis is rapidly gaining popularity amongst chemists. Compared to traditional synthetic methodologies biocatalysis offers a number of advantages in terms of enhanced selectivity (chemo-, regio-, stereo-), reduced environmental impact and lower cost of starting materials. Together these advantages can contribute to more sustainable manufacturing processes across a wide range of industries ranging from pharmaceuticals to biofuels. The biocatalytic toolbox has expanded significantly in the past five years and given the current rate of development of new engineered biocatalysts it is likely that the number of available biocatalysts will double in the next few years. This textbook gives a comprehensive overview of the current biocatalytic toolbox and also establishes new guidelines or rules for “biocatalytic retrosynthesis”. Retrosynthesis is a well known and commonly used technique whereby organic chemists start with the structure of their target molecule and generate potential starting materials and intermediates through a series of retrosynthetic disconnections. These disconnections are then used to devise a forward synthesis, in this case using biocatalytic transformations in some of the key steps. Target molecules are disconnected with consideration for applying biocatalysts, as well as chemical reagents and chemocatalysts, in the forward synthesis direction. Using this textbook, students will be able to place biocatalysis within the context of other synthetic transformations that they have learned earlier in their studies. This additional awareness of biocatalysis will equip students for the modern world of organic synthesis where biocatalysts play an increasingly important role. In addition to guidelines for identifying where biocatalysts can be applied in organic synthesis, this textbook also provides examples of current applications of biocatalysis using worked examples and case studies. Tutorials enable the reader to practice disconnecting target molecules to find the ‘hidden’ biocatalytic reactions which can be applied in the synthetic direction. The book contains a complete description of the current biocatalyst classes that are available for use and also suggests areas where new enzymes are likely to be developed in the next few years. This textbook is an essential resource for lecturers and students studying synthetic organic chemistry. It also serves as a handy reference for practicing chemists who wish to embed biocatalysis into their synthetic toolbox.Table of ContentsIntroduction and Aims of the Book; Biocatalysis Basics and Principles; Hydrolysis; Reverse Hydrolysis: Reduction; Oxidation; C–X Bond Formation; C–C Bond Formation, Miscellaneous Biocatalysts; Biocatalytic Disconnections and Functional Group Interconversions; Comparison of Different Biocatalytic Routes to Target Molecules; Applications of Biocatalytic Retrosynthesis

    2 in stock

    £47.49

  • The Immortal Life of Henrietta Lacks

    Pan Macmillan The Immortal Life of Henrietta Lacks

    Book SynopsisRebeca Skloot is the author of The Immortal Life of Henrietta Lacks and an award-winning science writer whose articles have appeared in the New York Times Magazine and O, the Oprah Magazine, among others. She has worked as a correspondent for NPR's RadioLab and PBS's Nova ScienceNOW, and blogs about science, life, and writing at Culture Dish, hosted by Seed magazine. She also teaches creative nonfiction at the University of Memphis.

    £10.44

  • Toward a History of Epistemic Things Synthesizing

    Stanford University Press Toward a History of Epistemic Things Synthesizing

    Book SynopsisArguing for the primacy of the material arrangements of the laboratory in the dynamics of modern molecular biology, the author develops a new epistemology of experimentation in which research is treated as a process for producing epistemic things.Trade Review“This is one of the most profound works in the history and philosophy of science in decades. One seldom encounters works of such depth and originality; its conceptual framework and analytical tools are truly pathbreaking. The literary style of the work is inspiring in its poetic qualities, and the blend of wit, playfulness, rigor, and succinctness makes for captivating reading.”—Lily E. Kay, Massachusetts Institute of TechnologyTable of ContentsContents 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13.

    £25.19

  • Bioconjugate Techniques

    Elsevier Science Bioconjugate Techniques

    1 in stock

    Book SynopsisA guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab.Trade Review"Most of the chapters address specific systems and reagents such as (strept) avidin-biotin, silane coupling, buckyballs & fullerenes, antibodies, liposome conjugates, and modified nucleotides—as well as a few chapters on observation techniques such as fluorescent probes and isotopic labeling. Also new since the last edition is a chapter addressing immobilization in chromatography." --ProtoView.com, February 2014 "This is an incomparable and essential guide for any scientist involved in conjugating biologically active molecules. The new edition does not disappoint with its liberal use of color (especially in reaction schemes), expanded pages, and newly added chapters. For those interested in bioconjugate chemistry, you may soon find that this is the only book on your research library shelf!" Rating: 5 Stars --Doody.com, February 2014Table of Contents1. Introduction to Bioconjugation2. Functional Targets for Bioconjugation3. The Reactions of Bioconjugation4. Zero-Length Crosslinkers5. Homobifunctional Crosslinkers6. Heterobifunctional Crosslinkers7. Trifunctional Crosslinkers8. Dendrimers and Dendrons9. Cross-Bridges and Cleavable Reagent Systems10. Fluorescent Probes11. (Strept)avidin - Biotin Systems12. Isotopic Labeling Techniques13. Silane Coupling Agents14. Microparticles and Nanoparticles15. Immobilization of Ligands on Chromatography Supports16. Buckyballs, Fullerenes, and Carbon Nanotubes17. Chemoselective Ligation; Bioorthogonal Reagents18. PEGylation & Synthetic Polymer Modification19. Vaccine and Immunogen Conjugates20. Antibody Modification and Conjugation21. Liposome Conjugates and Derivatives22. Enzyme Modification and Conjugation23. Nucleic Acid and Oligonucleotide Modification and Conjugation24. Bioconjugation for the Study of Protein Interactions

    1 in stock

    £88.19

  • Biochemistry

    Oxford University Press Inc Biochemistry

    1 in stock

    Book SynopsisBiochemistry: The Molecular Basis of Life is an intermediate, one-semester text written for students on degree pathways in Chemistry, Biology, and other Health and Life Sciences. Designed for students who need a solid introduction to biochemistry, but are not specializing in the subject, the text focuses on essential biochemical principles that underpin the modern life sciences, and offers the most balanced coverage of chemistry and biology of any text on the market. The text equips students with a complete view of the living state, emphasizes problem solving, and applies biochemical principles to the fields of Health, Agriculture, Engineering, and Forensics, to show students the relevance of their learning. McKee and McKee is respected for its balance of biology and chemistry, consistently placing biochemical principles into the context of the physiology of the cell and biomedical applications.Trade ReviewMcKee's Biochemistry is by far the best available textbook on the market for a one semester undergraduate Biochemistry course. It is very reader-friendly and has a better flow than most Biochemistry textbooks. This textbook goes beyond being a good reference book for students. Several features like key concepts, medical correlations, chapter summaries, 'Biochemistry in Perspective,' and end-of-chapter problems help guide learning and provide valuable study materials. * Niina Ronkainen, Benedictine University *McKee's Biochemistry is an excellent, one-semester biochemistry text that covers the major topics to an appropriate depth for health professions students. It is concise yet provides enough details to lay a solid biochemistry foundation. * Joe Deweese, Lipscomb University *The amount of material covered and the depth of the coverage is very good for a one-semester biochemistry course. The clinical examples to start each chapter are very nice and a good way to interest students in the material. The writing is at a level that will be helpful to students. * Michael Gunther, West Virginia University *Table of ContentsChapter Opening Vignettes Biochemistry in Perspective Essays Biochemistry in the Lab Boxes Preface General and Organic Chemistry Review Primer 1. Biochemistry: An Introduction 2. Living Cells 3. Water: The Matrix of Life 4. Energy 5. Amino Acids, Peptides, and Proteins 6. Enzymes 7. Carbohydrates 8. Carbohydrate Metabolism 9. Aerobic Metabolism I: The Citric Acid Cycle 10. Aerobic Metabolism II: Electron Transport and Oxidative Phosphorylation 11. Lipids and Membranes 12. Lipid Metabolism 13. Photosynthesis 14. Nitrogen Metabolism I: Synthesis 15. Nitrogen Metabolism II: Degradation 16. Integration of Metabolism 17. Nucleic Acids 18. Genetic Information 19. Protein Synthesis Appendix: Solutions Credits

    1 in stock

    £136.79

  • The Elements of Murder

    Oxford University Press The Elements of Murder

    2 in stock

    Book SynopsisThis book is about elements that kill. Mercury, arsenic, antimony, lead, and thallium can be lethal, as many a poisoner knew too well. Emsley explores the gruesome history of these elements and those who have succumbed to them in a fascinating narrative that weaves together stories of true crime, enduring historical mysteries, tragic accidents, and the science behind it all. The colourful cast includes ancient alchemists, kings, leaders, a pope, several great musicians, and a motley crew of murderers. Among the intriguing accounts is that of the 17th century poet Sir Thomas Overbury, who survived four attempts to poison him with mercury but died when given the poison in enema form - under whose direction remains uncertain. Here, too, is detailed the celebrated case of Florence Maybrick, convicted of poisoning her violent husband James with arsenic, but widely believed at the time to be innocent. The question of her guilt is still disputed.Threaded through the book alongside the history is the growing understanding of chemistry, and the effects of different chemical substances on the human body. Thousands suffered the ill effects of poisonous vapours from mercury, lead, and arsenic before the dangers were realized. Hatters went mad because of mercury poisoning, and hundreds of young girls working in factories manufacturing wallpaper in the 19th century were poisoned by the arsenic-based green pigments used for the leaves of the popular floral designs. Even in the middle of the 20th century, accidental mercury poisoning caused many deaths in Minamata Bay, while leaded petrol poisoned the whole planet, and arsenic still continues to poison millions is Asia.Through vividly told stories of innocent blunders, industrial accidents, poisoners of various hues - cold, cunning, desperate - and deaths that remain a mystery, Emsley here uncovers the dark side of the Periodic Table.Trade ReviewReview from previous edition A readable anecdotal history of killing. This book will be enjoyed by those who like good detective stories, intriguing snippets of history, popular science and murder most foul. * Chemistry World *...authoritative and meticulously researched... Emsley knows what he is talking about. This is a lovely book. * Roger P Smith, Nature Vol 436 *A delightful potion of chemical erudition, forgotten science history and ghastly murder schemes Along the way, the bodies pile up as Emsley relates spectacular case histories of poisonings, accidental and criminal...Reading ''The Elements of Murder'' is like watching a hundred episodes of ''CSI,'' but without having to sit through the tedious personal relationships of the characters. * New York Times Book Review *...fascinating, wide-ranging and, let's not mince words, macabre new history of poison...a truly guilty pleasureFascinating brew of academic research and titilating murder mysteries...vivid and anecdotal history of poison * Daily Mail *He describes the chemistry with a light touch that makes the book accessible to non-chemists and, indeed, non-scientists. There is much here to fascinate a broad readership. * THES *a fascinating ancedotal history of killing. With something of interest on almost every page, it combines the satisfaction of a detective story, intriguing snippets of history, popular science, unsolved mysteries and murder. A powerful brew. * Telegraph *Meticulously researched, this book reads like a novel and a reader could pick up enough colourful anecdotes on which to dine out some time. Just be careful what, or whom, you eat. * Lancet *Meticulously researched, this book reads like a novel and a reader could pick up enough colourful anecdotes on which to dine out for some time. * The Lancet *Endlessly fascinating book...Every page reveals delights and horrors...It is the perfect book to take on a long-haul flight * Telegraph *The Elements of Murder is full of such intriguing nuggets...Emsley must have been an outstanding chemistry teacher.Table of Contents1. Deadly elements ; 2. The history and the chemistry ; 3. One man's medicine is another man's murder weapon ; 4. Arsenic and adultry ; 5. Off the wall poison ; 6. Insidious antimony ; 7. Requiem for a metal ; 8. Deadly lead ; 9. When the Empire struck lead ; 10. Mercury in the Tower ; 11. Mad cats and mad hatters ; 12. Young and deadly ; 13. Driving you hairless ; Glossary

    2 in stock

    £12.59

  • Fermentation for Your Culinary Delight

    Oxford University Press Fermentation for Your Culinary Delight

    2 in stock

    2 in stock

    £21.84

  • Physical Chemistry for the Life Sciences

    Oxford University Press Physical Chemistry for the Life Sciences

    2 in stock

    Book SynopsisA balanced presentation of the concepts of physical chemistry, and their applications to biology and biochemistry. Written to straddle the worlds of physical chemistry and the life sciences, it shows how the tools of physical chemistry can elucidate biological questions.Table of ContentsFocus 1: Biochemical Thermodynamics: The First Law Focus 2: Biochemical Thermodynamics: The Second Law Focus 3: Water and Aqueous solutions Focus 4: Chemical equilibrium Focus 5: Ion and Electron Transport Focus 6: The Rates of Reactions Focus 7: Biochemical kinetics Focus 8: Atoms Focus 9: Molecules Focus 10: Macromolecules and self-assembly Focus 11: Biochemical spectroscopy Focus 12: Scattering techniques Focus 13: Gravimetric methods

    2 in stock

    £137.74

  • Hormones

    Oxford University Press Hormones

    2 in stock

    Book SynopsisHormones are vital to the workings of the body, and while many people are aware of what hormones do, few have an appreciation of the nature and importance of the endocrine system. In this Very Short Introduction, Martin Luck explains what hormones are, what they do, where they come from, and how they work.Trade Reviewan informative and readable overview to the subject * Guardian *Table of Contents1. Hormones, history, and the shoulders of giants ; 2. What and how ; 3. Nuns, catastrophes, and the mysteries of reproduction ; 4. Water, salt, and blood pressure ; 5. The hard stuff: calcium, cells, bones, and cancer ; 6. Appetite, fat, and obesity ; 7. The thyroid gland ; 8. Light and dark ; 9. Changing perspectives ; Further reading ; Index

    2 in stock

    £9.49

  • A Mathematical Approach to Special Relativity

    Elsevier Science A Mathematical Approach to Special Relativity

    2 in stock

    Book SynopsisTable of Contents1. Galilean relativity 2. Lorentz Boosts 3. Development of the Formalism 4. Electrodynamics 5. Gravity 6. Experiments and Applications Part II: Mathematics 7. Mathematics of Translations 8. The Rotation Group 9. The Lorentz Group

    2 in stock

    £73.10

  • The Machinery of Life

    Springer-Verlag New York Inc. The Machinery of Life

    1 in stock

    Book SynopsisMolecular Machines.- The Processes of Living.- Molecules in Cells: Escherichia coli.- A Human Cell: The Advantages of Compartments.- The Human Body: The Advantages of Specialization.- Life and Death.- Viruses.- You and Your Molecules.Trade ReviewFrom the reviews of the second edition: "The Machinery of Life is a journey into the sub-microscopic world of molecular machines. Readers are introduced to the types of molecules within the cell, including proteins, nucleic acids, lipids and polysaccharides. … The Machinery of Life is a pictorial overview of the molecules that orchestrate the processes of life. … The book provides a fascinating introduction to biochemistry and molecular biology for the non-specialists … . It is written in clear, jargon-free text that is accessible to the lay reader." (Medical News Today, May, 2009) "This book is amazing. … this second edition is a major update. And what it conveys is the sheer unbelievable intricacy – and realness – of every cell in your body. David Goodsell … accomplishes this via amazing full-color illustrations, paintings based on computer animations created from microscope images. … It’s slim, readable and engaging, a nonfiction book that calls to you from the nightstand table. If you are even a little curious about how cells work, get your hands on The Machinery of Life." (Lisa Parsons, The Hippo, July, 2009) "The Machinery of Life, which is a new edition of Goodsell’s 1993 book of the same name. … the author’s full-color illustrations are astonishing, forcing the reader to dwell for minutes on every picture. They are based on data from scientific papers, electron microscopy and information about molecular structures that were obtained by X-ray crystallography. … He does a good job. … Goodsell’s technique is remarkable. He uses a combination of hand-drawing and computer graphics illustration." (Weanée Kimblewood, Lab Times, Issue 5, September, 2009) "Anyone who finds biology, especially modern biology at the molecular level, quite baffling and bristling with incomprehensible jargon – this could be the book for you! … David Goodsell is clearly a master of communication, conveying complex biological processes with great clarity. … An excellent gift, then, for anyone interested in learning about biology in an enjoyable way. A book bursting with colour and genuinely difficult to put down … ." (Michael Smith, Chemistry World, December, 2009) “In science, true understanding comes with the ability to visualize the system. For students of cell and molecular biology, this visualization often comes in the form of diagrams simplified in the name of clarity. … Using coordinates taken from the RCSB Protein Data Bank, Goodsell’s wonderfully drawn illustrations are true to the scale and shape of the real molecules. … This work will be enjoyed by all who are interested in the molecular processes … from new students to experienced scientists. Summing Up: Highly recommended.” (D. Carroll, Choice, Vol. 47 (4), December, 2009) “This well-written, beautifully illustrated volume serves as an introduction to the molecules that compose cells and viruses. The book is written at a very accessible level and is appropriate for nonspecialists and students beginning their study in biology. … experienced biologists will appreciate the lucid treatment of complex concepts, particularly the idea of molecular crowding in cells. … In summary, the easy-to-read narrative and beautiful illustrations of The Machinery of Life make this volume worthwhile to recommend to both nonspecialists as well as practicing biologists.” (A. James Link, The Quarterly Review of Biology, Vol. 85 (1), March, 2010)Table of ContentsIntroduction.- Part I: Molecules and Life: Molecular Machines.- The Processes of Living.- Part II: Molecules into Cells: Escherichia coli: One of the Simplest Cells.- Baker’s Yeast: The Advantages of Compartmentation.- Human Beings: The Advantages of Specialization.- Plants: Gathering Energy from the Sun.- Part III: Cells in Health and Disease: Life and Death.- Vitamins.- Viruses: Biological Hijackers.- Poisons and Drugs.

    1 in stock

    £26.99

  • Biochemistry and Molecular Biology of Plants

    John Wiley & Sons Inc Biochemistry and Molecular Biology of Plants

    2 in stock

    Book Synopsis* A major new edition of this highly successful, authoritative, superbly illustrated text * Distinguished, internationally renowned Editors * Completely revised with over half of the chapters having a major rewrite * Includes two new chapters on signal transduction and responses to pathogens .Trade Review“Biochemistry and Molecular Biology of Plants, 2nd edi­tion is a beast, but it’s a user-friendly one that should be wel­comed into one’s life to provide much-appreciated com­pan­ion­ship to fur­ther one’s plant bio­logy studies.” (AoB Blog, 1 November 2015) Table of ContentsThe Editors xi List of Contributors xii Preface xv About the Companion Website xvi COMPARTMENTS 1 Membrane Structure and Membranous Organelles 2 Introduction 2 1.1 Common properties and inheritance of cell membranes 2 1.2 The fluid-mosaic membrane model 4 1.3 Plasma membrane 10 1.4 Endoplasmic reticulum 13 1.5 Golgi apparatus 18 1.6 Exocytosis and endocytosis 23 1.7 Vacuoles 27 1.8 The nucleus 28 1.9 Peroxisomes 31 1.10 Plastids 32 1.11 Mitochondria 39 Summary 44 2 The Cell Wall 45 Introduction 45 2.1 Sugars are building blocks of the cell wall 45 2.2 Macromolecules of the cell wall 51 2.3 Cell wall architecture 73 2.4 Cell wall biosynthesis and assembly 80 2.5 Growth and cell walls 90 2.6 Cell differentiation 99 2.7 Cell walls as sources of food, feed, fiber, and fuel, and their genetic improvement 108 Summary 110 3 Membrane Transport 111 Introduction 111 3.1 Overview of plant membrane transport systems 111 3.2 Pumps 120 3.3 Ion channels 128 3.4 Cotransporters 142 3.5 Water transport through aquaporins 146 Summary 148 4 Protein Sorting and Vesicle Traffic 151 Introduction 151 4.1 The cellular machinery of protein sorting 151 4.2 Targeting proteins to the plastids 153 4.3 Targeting proteins to mitochondria 157 4.4 Targeting proteins to peroxisomes 159 4.5 Transport in and out of the nucleus 160 4.6 ER is the secretory pathway port of entry and a protein nursery 161 4.7 Protein traffic and sorting in the secretory pathway: the ER 175 4.8 Protein traffic and sorting in the secretory pathway: the Golgi apparatus and beyond 182 4.9 Endocytosis and endosomal compartments 188 Summary 189 5 The Cytoskeleton 191 Introduction 191 5.1 Introduction to the cytoskeleton 191 5.2 Actin and tubulin gene families 194 5.3 Characteristics of actin filaments and microtubules 196 5.4 Cytoskeletal accessory proteins 202 5.5 Observing the cytoskeleton: Statics and dynamics 207 5.6 Role of actin filaments in directed intracellular movement 210 5.7 Cortical microtubules and expansion 216 5.8 The cytoskeleton and signal transduction 219 5.9 Mitosis and cytokinesis 222 Summary 238 CELL REPRODUCTION 6 Nucleic Acids 240 Introduction 240 6.1 Composition of nucleic acids and synthesis of nucleotides 240 6.2 Replication of nuclear DNA 245 6.3 DNA repair 250 6.4 DNA recombination 255 6.5 Organellar DNA 260 6.6 DNA transcription 268 6.7 Characteristics and functions of RNA 270 6.8 RNA processing 278 Summary 288 7 Amino Acids 289 Introduction 289 7.1 Amino acid biosynthesis in plants: research and prospects 289 7.2 Assimilation of inorganic nitrogen into N-transport amino acids 292 7.3 Aromatic amino acids 302 7.4 Aspartate-derived amino acids 318 7.5 Branched-chain amino acids 326 7.6 Glutamate-derived amino acids 330 7.7 Histidine 333 Summary 336 8 Lipids 336 Introduction 337 8.1 Structure and function of lipids 337 8.2 Fatty acid biosynthesis 344 8.3 Acetyl-CoA carboxylase 348 8.4 Fatty acid synthase 350 8.5 Desaturation and elongation of C16 and C18 fatty acids 352 8.6 Synthesis of unusual fatty acids 360 8.7 Synthesis of membrane lipids 365 8.8 Function of membrane lipids 373 8.9 Synthesis and function of extracellular lipids 382 8.10 Synthesis and catabolism of storage lipids 389 8.11 Genetic engineering of lipids 395 Summary 400 9 Genome Structure and Organization 401 Introduction 401 9.1 Genome structure: a 21st]century perspective 401 9.2 Genome organization 404 9.3 Transposable elements 416 9.4 Gene expression 422 9.5 Chromatin and the epigenetic regulation of gene expression 430 Summary 436 10 Protein Synthesis, Folding, and Degradation 438 Introduction 438 10.1 Organellar compartmentalization of protein synthesis 438 10.2 From RNA to protein 439 10.3 Mechanisms of plant viral translation 447 10.4 Protein synthesis in plastids 450 10.5 Post-translational modification of proteins 457 10.6 Protein degradation 463 Summary 475 11 Cell Division 476 Introduction 476 11.1 Animal and plant cell cycles 476 11.2 Historical perspective on cell cycle research 477 11.3 Mechanisms of cell cycle control 482 11.4 The cell cycle in action 488 11.5 Cell cycle control during development 497 Summary 506 ENERGY FLOW 12 Photosynthesis 508 Introduction 508 12.1 Overview of photosynthesis 508 12.2 Light absorption and energy conversion 511 12.3 Photosystem structure and function 519 12.4 Electron transport pathways in chloroplast membranes 529 12.5 ATP synthesis in chloroplasts 537 12.6 Organization and regulation of photosynthetic complexes 540 12.7 Carbon reactions: the Calvin-Benson cycle 542 12.8 Rubisco 548 12.9 Regulation of the Calvin-Benson cycle by light 551 12.10 Variations in mechanisms of CO 2 fixation 557 Summary 565 13 Carbohydrate Metabolism 567 Introduction 567 13.1 The concept of metabolite pools 570 13.2 The hexose phosphate pool: a major crossroads in plant metabolism 571 13.3 Sucrose biosynthesis 573 13.4 Sucrose metabolism 577 13.5 Starch biosynthesis 580 13.6 Partitioning of photoassimilates between sucrose and starch 587 13.7 Starch degradation 593 13.8 The pentose phosphate/triose phosphate pool 597 13.9 Energy and reducing power for biosynthesis 601 13.10 Sugar-regulated gene expression 606 Summary 608 14 Respiration and Photorespiration 610 Introduction 610 14.1 Overview of respiration 610 14.2 Citric acid cycle 613 14.3 Plant mitochondrial electron transport 620 14.4 Plant mitochondrial ATP synthesis 632 14.5 Regulation of the citric acid cycle and the cytochrome pathway 634 14.6 Integration of the cytochrome pathway and nonphosphorylating pathways 635 14.7 Interactions between mitochondria and other cellular compartments 639 14.8 Biochemical basis of photorespiration 646 14.9 The photorespiratory pathway 648 14.10 Role of photorespiration in plants 652 Summary 655 METABOLIC AND DEVELOPMENTAL INTEGRATION 15 Long]Distance Transport 658 Introduction 658 15.1 Selection pressures and long-distance transport systems 658 15.2 Cell biology of transport modules 664 15.3 Short-distance transport events between xylem and nonvascular cells 668 15.4 Short-]distance transport events between phloem and nonvascular cells 673 15.5 Whole-plant organization of xylem transport 691 15.6 Whole-plant organization of phloem transport 696 15.7 Communication and regulation controlling phloem transport events 705 Summary 710 16 Nitrogen and Sulfur 711 Introduction 711 16.1 Overview of nitrogen in the biosphere and in plants 711 16.2 Overview of biological nitrogen fixation 715 16.3 Enzymology of nitrogen fixation 715 16.4 Symbiotic nitrogen fixation 718 16.5 Ammonia uptake and transport 735 16.6 Nitrate uptake and transport 735 16.7 Nitrate reduction 739 16.8 Nitrite reduction 744 16.9 Nitrate signaling 745 16.10 Interaction between nitrate assimilation and carbon metabolism 745 16.11 Overview of sulfur in the biosphere and plants 746 16.12 Sulfur chemistry and function 747 16.13 Sulfate uptake and transport 750 16.14 The reductive sulfate assimilation pathway 752 16.15 Cysteine synthesis 755 16.16 Synthesis and function of glutathione and its derivatives 758 16.17 Sulfated compounds 763 16.18 Regulation of sulfate assimilation and interaction with nitrogen and carbon metabolism 764 Summary 767 17 Biosynthesis of Hormones 769 Introduction 769 17.1 Gibberellins 769 17.2 Abscisic acid 777 17.3 Cytokinins 785 17.4 Auxins 795 17.5 Ethylene 806 17.6 Brassinosteroids 810 17.7 Polyamines 818 17.8 Jasmonic acid 821 17.9 Salicylic acid 826 17.10 Strigolactones 830 Summary 833 18 Signal Transduction 834 Introduction 834 18.1 Characteristics of signal perception, transduction, and integration in plants 834 18.2 Overview of signal perception at the plasma membrane 838 18.3 Intracellular signal transduction, amplification, and integration via second messengers and MAPK cascades 843 18.4 Ethylene signal transduction 847 18.5 Cytokinin signal transduction 850 18.6 Integration of auxin signaling and transport 852 18.7 Signal transduction from phytochromes 857 18.8 Gibberellin signal transduction and its integration with phytochrome signaling during seedling development 861 18.9 Integration of light, ABA, and CO2 signals in the regulation of stomatal aperture 866 18.10 Prospects 870 Summary 870 19 Molecular Regulation of Reproductive Development 872 Introduction 872 19.1 The transition from vegetative to reproductive development 872 19.2 The molecular basis of flower development 881 19.3 The formation of male gametes 889 19.4 The formation of female gametes 897 19.5 Pollination and fertilization 902 19.6 The molecular basis of self]incompatibility 908 19.7 Seed development 913 Summary 923 20 Senescence and Cell Death 925 Introduction 925 20.1 Types of cell death 925 20.2 PCD during seed development and germination 930 20.3 Cell death during the development of secretory bodies, defensive structures and organ shapes 932 20.4 PCD during reproductive development 937 20.5 Senescence and PCD in the terminal development of leaves and other lateral organs 940 20.6 Pigment metabolism in senescence 948 20.7 Macromolecule breakdown and salvage of nutrients in senescence 951 20.8 Energy and oxidative metabolism during senescence 957 20.9 Environmental influences on senescence and cell death I: Abiotic interactions 961 20.10 Environmental influences on senescence and cell death II: PCD responses to pathogen attack 964 20.11 Plant hormones in senescence and defense-related PCD 974 Summary 982 PLANT ENVIRONMENT AND AGRICULTURE 21 Responses to Plant Pathogens 984 Introduction 984 21.1 Pathogens, pests, and disease 984 21.2 An overview of immunity and defense 985 21.3 How pathogens and pests cause disease 989 21.4 Preformed defenses 1009 21.5 Induced defense 1012 21.6 Effector-triggered immunity, a second level of induced defense 1022 21.7 Other sources of genetic variation for resistance 1032 21.8 Local and systemic defense signaling 1033 21.9 Plant gene silencing confers virus resistance, tolerance, and attenuation 1042 21.10 Control of plant pathogens by genetic engineering 1044 Summary 1050 22 Responses to Abiotic Stress 1051 Introduction 1051 22.1 Plant responses to abiotic stress 1051 22.2 Physiological and cellular responses to water deficit 1054 22.3 Gene expression and signal transduction in response to dehydration 1061 22.4 Freezing and chilling stress 1068 22.5 Flooding and oxygen deficit 1076 22.6 Oxidative stress 1085 22.7 Heat stress 1094 22.8 Crosstalk in stress responses 1097 Summary 1099 23 Mineral Nutrient Acquisition, Transport, and Utilization 1101 Introduction 1101 23.1 Overview of essential mineral elements 1102 23.2 Mechanisms and regulation of plant K+ transport 1103 23.3 Phosphorus nutrition and transport 1113 23.4 The molecular physiology of micronutrient acquisition 1118 23.5 Plant responses to mineral toxicity 1127 Summary 1131 24 Natural Products 1132 Introduction 1132 24.1 Terpenoids 1133 24.2 Biosynthesis of the basic five-carbon unit 1135 24.3 Repetitive additions of C5 units 1138 24.4 Formation of parent carbon skeletons 1141 24.5 Modification of terpenoid skeletons 1143 24.6 Metabolic engineering of terpenoid production 1145 24.7 Cyanogenic glycosides 1146 24.8 Cyanogenic glycoside biosynthesis 1152 24.9 Functions of cyanogenic glycosides 1157 24.10 Glucosinolates 1158 24.11 Alkaloids 1159 24.12 Alkaloid biosynthesis 1164 24.13 Biotechnological application of alkaloid biosynthesis research 1171 24.14 Phenolic compounds 1178 24.15 Phenolic biosynthesis 1185 24.16 The phenylpropanoid-acetate pathway 1188 24.17 The phenylpropanoid pathway 1195 24.18 Universal features of phenolic biosynthesis 1202 24.19 Evolution of secondary pathways 1205 Summary 1206 Further reading 1207 Index 1222

    2 in stock

    £95.90

  • Principles of Biochemistry

    Pearson Education Principles of Biochemistry

    2 in stock

    Book SynopsisLaurence A. MoranAfter earning his Ph.D from Princeton University in 1974, Professor Moran spent four years at the Université dè Geneve in Switzerland. He has been a member of the Department of Biochemistry at the University of Toronto since 1978, specializing in molecular biology and molecular evolution. His research findings on heat-shock genes have been published in many scholarly journals.H. Robert HortonDr. Horton, who received his Ph.D from the University of Missouri in 1962, is William Neal Reynolds Professor Emeritus and Alumni Distinguished Professor Emeritus in the Department of Biochemistry at North Carolina State University, where he served on the faculty for over 30 years. Most of Professor Horton's research was in protein and enzyme mechanisms.K. Gray ScrimgeourProfessor Scrimgeour received his doctorate from the University of Washington in 1961 and has been a faculty member at the University of TorTable of Contents(NOTE: Each chapter concludes with Summary, Problems, and Selected Reading.)Part One: Introduction1 Introduction to Biochemistry2 WaterPart Two: Structure and Function3 Amino Acids and the Primary Structures of Proteins4 Proteins: Three-Dimensional Structure and Function5 Properties of Enzymes6 Mechanisms of Enzymes7 Carbohydrates 8 Coenzymes and Vitamins9 Lipids and MembranesPart Three: Metabolism and Bioenergetics 10 Introduction to Metabolism11 Glycolysis12 Gluconeogenesis, The Pentose Phosphate Pathway, and Glycogen Metabolism13 The Citric Acid Cycle14 Electron Transport and ATP Synthesis15 Photosynthesis16 Lipid Metabolism17 Amino Acid Metabolism18 Nucleotide MetabolismPart Four: Biological Information Flow19 Nucleic Acids20 DNA Replication, Repair, and Recombination21 Transcription and RNA Processing22 Protein Synthesis

    2 in stock

    £78.99

  • Making Medicine: Surprising Stories from the

    Prometheus Books Making Medicine: Surprising Stories from the

    2 in stock

    Book SynopsisHow do scientists design the medicine we use to improve our lives? It turns out that many are happy accidents or overlooked mixtures of carbon and hydrogen that go on to not only improve the lives of people the world over, but become million- and billion-dollar makers for pharmaceutical companies.In Making Medicine: Surprising Stories from the History of Drug Discovery, author Keith Veronese examines eighteen different molecules and their unlikely discovery –or in many cases, their second discovery –en route to becoming invaluable medications. From the famous story of Alexander Fleming’s discovery of penicillin, to lesser-known stories surrounding drugs like quinine (derived from the bark of the cinchona tree and responsible for saving the lives of millions in the fight against malaria), Veronese reveals the “how” and the “who” behind the pharmaceutical breakthroughs that continue to impact our world. With subjects including cancer-fighting therapies and over-the-counter pain relievers; hair regrowth creams and antidepressants; readers will no doubt have a personal connection to at least one molecule in this book.Like all discoveries made by mankind, the stories behind these breakthroughs and their introduction to the world are often messy, sometimes controversial, and always human. Take digoxin, which correctly prescribed can help heart efficiency, but in higher doses can prove fatal –a fact known all too well by Charles Cullen, a nurse who used digoxin to kill over forty patients. Making Medicine also details how modern pharmaceutical discovery works, highlighting the serendipitous nature of the discovery of these miracle molecules, along with how they do (or don't) interact with the human body to produce the desired result.

    2 in stock

    £17.99

  • Key Questions in Environmental Toxicology: A

    CABI Publishing Key Questions in Environmental Toxicology: A

    2 in stock

    Book SynopsisKey Questions in Environmental Toxicology is designed as a self-study tool for undergraduate students. Questions review the origin, characterization and environmental distribution of major pollutants, followed by their absorption and metabolic disposition in living organisms. They address implications for the development of cancer, cardiovascular disease, pulmonary dysfunction and neurological conditions in relation to gaseous pollutants, particulates, persistent organic compounds and radioactive emissions, then cover the impact of pollutants on biodiversity, food safety, and water contamination. This book: - Covers toxicology from human morbidity, ecological impact and biodiversity perspectives, and emphasises the impact of diverse organic pollutants in worsening these interconnected phenomena, leading to wider environmental emergencies; - Provides a selection of fill-in-the-gap, multiple choice and short answer question types for students to vary their learning and enhance motivation; - Includes full answer rationales, allowing students to gain true insight into the subject. Providing support to programmes across environmental science, ecology and human health, and covering all the major biological toxins and pollutants as well as unintended consequences of actions designed to improve outcomes, this book may be used in conjunction with the companion volume Introduction to Environmental Toxicology.

    2 in stock

    £24.70

  • Protein Folding: An Introduction

    Springer International Publishing AG Protein Folding: An Introduction

    2 in stock

    Book SynopsisThis snapshot volume is designed to provide a smooth entry into the field of protein folding. Presented in a concise manner, each section introduces key concepts while providing a brief overview of the relevant literature. Outlook subsections will pinpoint specific aspects related to emerging methodologies, concepts and trends.Table of ContentsProtein Structure: How is structure maintained?.- Protein Folding: Why is structure acquired?.- Folding Kinetics and Mechanisms: How is structure acquired?.- Protein Misfolding: Why proteins misbehave?.- Methods for Protein Folding.

    2 in stock

    £39.59

  • Modern Biophysical Chemistry: Detection and

    Wiley-VCH Verlag GmbH Modern Biophysical Chemistry: Detection and

    2 in stock

    Book SynopsisThis updated and up-to-date version of the first edition continues with the really interesting stuff to spice up a standard biophysics and biophysical chemistry course. All relevant methods used in current cutting edge research including such recent developments as super-resolution microscopy and next-generation DNA sequencing techniques, as well as industrial applications, are explained. The text has been developed from a graduate course taught by the author for several years, and by presenting a mix of basic theory and real-life examples, he closes the gap between theory and experiment. The first part, on basic biophysical chemistry, surveys fundamental and spectroscopic techniques as well as biomolecular properties that represent the modern standard and are also the basis for the more sophisticated technologies discussed later in the book. The second part covers the latest bioanalytical techniques such as the mentioned super-resolution and next generation sequencing methods, confocal fluorescence microscopy, light sheet microscopy, two-photon microscopy and ultrafast spectroscopy, single molecule optical, electrical and force measurements, fluorescence correlation spectroscopy, optical tweezers, quantum dots and DNA origami techniques. Both the text and illustrations have been prepared in a clear and accessible style, with extended and updated exercises (and their solutions) accompanying each chapter. Readers with a basic understanding of biochemistry and/or biophysics will quickly gain an overview of cutting edge technology for the biophysical analysis of proteins, nucleic acids and other biomolecules and their interactions. Equally, any student contemplating a career in the chemical, pharmaceutical or bio-industry will greatly benefit from the technological knowledge presented. Questions of differing complexity testing the reader's understanding can be found at the end of each chapter with clearly described solutions available on the Wiley-VCH textbook homepage under: www.wiley-vch.de/textbooksTable of ContentsIntroduction: What is Biophysical Chemistry? - An Example from Drug Screening PART I: Basic Methods in Biophysical Chemistry BASIC OPTICAL PRINCIPLES Introduction What Does the Electronic Structure of Molecules Look Like? Orbitals, Wave Functions and Bonding Interactions How Does Light Interact with Molecules? Transition Densities and the Transition Dipole Moment Absorption Spectra of Molecules in Liquid Environments. Vibrational Excitation and the Franck-Condon Principle What Happens After Molecules have Absorbed Light? Fluorescence, Nonradiative Transitions and the Triplet State Quantitative Description of all Processes: Quantum Efficiencies, Kinetics of Excited State Populations and the Jablonski Diagram Problems OPTICAL PROPERTIES OF BIOMOLECULES Introduction Experimental Determination of Absorption and Fluorescence Spectra Optical Properties of Proteins and DNA Optical Properties of Important Cofactors BASIC FLUORESCENCE TECHNQUES Introduction Fluorescent Labelling and Linking Techniques Fluorescence Detection Techniques Fluorscence Polarization Anisotropy Forster Resonance Energy Transfer Fluorescence Kinetics Fluorescence Recovery after Photobleaching Biochemiluminescence CHIROPTICAL AND SCATTERING METHODS Chiroptical Methods Light Scattering Vibrational Spectra of Biomolecules MAGNETIC RESONANCE TECHNIQUES Nuclear Magnetic Resonance of Biomolecules Electron Paramagnetic Resonance MASS SPECTROMETRY Introduction MALDI-TOF ESI-MS Structural and Sequence Analysis Using Mass Spectrometry PART II: Advanced Methods in Biophysical Chemistry FLUORESCENCE MICROSCOPY Introduction Conventional Fluorescence Microscopy Total Internal Reflection Fluorescence Microscopy Light-Sheet Microscopy SUPER-RESOLUTION FLUORESCENCE MICROSCOPY Stimulated Emission Depletion (STED) Microscopy Photoactivated Localization Microscopy (PALM) and Stochastic Optical Reconstruction Microscopy (STORM) 3D Super-Resolution Fluorescence Microscopy Imaging of Live Cells Multicolour Super-Resolution Fluorescence Microscopy Structured Illumination Microscopy SOFI Final Comparison SINGLE-BIOMOLECULE TECHNIQUES Introduction Optical Single-Molecule Detection Fluorescence Correlation Spectroscopy Optical Tweezers Atomic Force Microscopy of Biomolecules Patch Clamping ULTRAFAST- AND NONLINEAR SPECTROSCOPY Introduction Nonlinear Microscopy and Spectroscopy Ultrafast Spectroscopy DNA SEQUENCING AND NEXT-GENERATION SEQUENCING METHODS Sanger Method Next-Generation Sequencing Methods SPECIAL TECHNIQUES Introduction Fluorescing Nanoparticles Surface Plasmon Resonance Detection DNA Origami DNA Microarrays Flow Cytometry Fluorescence In Situ Hybridization Microspheres and Nanospheres ASSAY DEVELOPMENT, READERS AND HIGH-THROUGHPUT SCREENING Introduction Assay Development and Assay Quality Microtitre Plates and Fluorescence Readers Application Example: Drug Discovery and High-Throughput Screening Index

    2 in stock

    £51.00

  • Biochemistry

    Macmillan Learning Biochemistry

    4 in stock

    Book Synopsis

    4 in stock

    £75.04

  • Exercise Biochemistry

    Human Kinetics Publishers Exercise Biochemistry

    Book Synopsis Exercise Biochemistry brings an admittedly difficult and technical subject to life. Extremely user- and student-friendly, it is written in conversational style by Vassilis Mougios, who poses and then answers questions as if in conversation with a student. Mougios does an excellent job of making the information interesting by using simple language without compromising scientific accuracy and content. He also uses ample analogies, related works of art, and numerous illustrations to drive home his points for readers. The result is that Exercise Biochemistry is a highly informative and illuminating text on the effects of exercise on molecular-level functioning. It presents the basics of biochemistry as well as in-depth coverage of exercise biochemistry. The book uses key terms, sidebars, and questions and problems posed at the end of each chapter to facilitate learning. It also covers metabolism, endocrinology, and assessment all in one volume, unlike other exer Table of Contents Part I. Biochemistry Basics Chapter 1. Introduction 1.1 Chemical Elements 1.2 Chemical Bonds 1.3 Molecules 1.4 Ions 1.5 Radicals 1.6 Polarity Influences Miscibility 1.7 Solutions 1.8 Chemical Reactions 1.9 Chemical Equilibrium 1.10 pH 1.11 Acid-Base Interconversions 1.12 Buffer Systems 1.13 Classes of Biological Substances 1.14 Classes of Nutrients 1.15 Cell Structure Chapter 2. Metabolism 2.1 Free-Energy Changes of Metabolic Reactions 2.2 Determinants of Free-Energy Change 2.3 ATP, the Energy Currency of Cells 2.4 Phases of Metabolism 2.5 Redox Reactions 2.6 Overview of Catabolism Chapter 3. Proteins 3.1 Amino Acids 3.2 The Peptide Bond 3.3 Primary Structure of Proteins 3.4 Secondary Structure 3.5 Tertiary Structure 3.6 Denaturation 3.7 Quaternary Structure 3.8 Protein Function 3.9 Oxygen Carriers 3.10 Myoglobin 3.11 Hemoglobin Structure 3.12 The Wondrous Properties of Hemoglobin 3.13 Enzymes 3.14 The Active Site 3.15 How Enzymes Speed up Metabolic Reactions 3.16 Factors Affecting the Rate of Enzyme Reactions Chapter 4. Nucleic Acids and Gene Expression 4.1 Introducing Nucleic Acids 4.2 Flow of Genetic Information 4.3 Deoxyribonucleotides, the Building Blocks of DNA 4.4 Primary Structure of DNA 4.5 The Double Helix of DNA 4.6 The Genome of Living Organisms 4.7 DNA Replication 4.8 Mutations 4.9 RNA 4.10 Transcription 4.11 Delimiting Transcription 4.12 Genes and Gene Expression 4.13 Messenger RNA 4.14 Translation 4.15 The Genetic Code 4.16 Transfer RNA 4.17 Translation Continued 4.18 In the Beginning, RNA? Chapter 5. Carbohydrates and Lipids 5.1 Carbohydrates 5.2 Monosaccharides 5.3 Oligosaccharides 5.4 Polysaccharides 5.5 Carbohydrate Categories in Nutrition 5.6 Lipids 5.7 Fatty Acids 5.8 Triacylglycerols 5.9 Phospholipids 5.10 Steroids 5.11 Cell Membranes Chapter 6. Vitamins and Minerals 6.1 Water Soluble Vitamins 6.2 Fat Soluble Vitamins 6.3 Metal Minerals 6.4 Nonmetal Minerals 6.5 Elements in the Human Body Part II. Biochemistry of the Neural and Muscular Processes of Movement Chapter 7. Neural Control of Movement 7.1 Two Ways of Transmission of Nerve Signals 7.2 The Resting Potential 7.3 The Action Potential 7.4 Propagation of an Action Potential 7.5 Transmission of a Nerve Impulse from One Neuron to Another 7.6 Birth of a Nerve Impulse 7.7 The Neuromuscular Junction 7.8 Changes in Motor Neuron Activity During Exercise 7.9 A Lethal Arsenal at the Service of Research Chapter 8. Muscle Activity 8.1 Structure of a Muscle Cell 8.2 The Sliding-Filament Theory 8.3 The Wondrous Properties of Myosin 8.4 Myosin Structure 8.5 Actin 8.6 Sarcomere Architecture 8.7 Mechanism of Force Generation 8.8 Myosin Isoforms and Muscle Fiber Types 8.9 Control of Muscle Contraction by Ca2+ 8.10 Excitation-Contraction Coupling Part III. Exercise Metabolism III.1 Principles of Exercise Metabolism III.2 Exercise Parameters III.3 Experimental Models Used to Study Exercise Metabolism III.4 Five Means of Metabolic Control in Exercise III.5 Four Classes of Energy Sources in Exercise Chapter 9. Compounds of High Phosphoryl Transfer Potential 9.1 The ATP-ADP Cycle 9.2 The ATP-ADP Cycle in Exercise 9.3 Phosphocreatine 9.4 Watching Exercise Metabolism 9.5 Loss of AMP by Deamination 9.6 Purine Degradation Chapter 10. Carbohydrate Metabolism in Exercise 10.1 Carbohydrate Digestion and Absorption 10.2 Glycogen Content of the Human Body 10.3 Glycogenesis 10.4 Glycogenolysis 10.5 Exercise Speeds Up Glycogenolysis in Muscle 10.6 The Cyclic-AMP Cascade 10.7 Recapping the Effect of Exercise on Muscle Glycogen Metabolism 10.8 Glycolysis 10.9 Exercise Speeds Up Glycolysis in Muscle 10.10 Pyruvate Oxidation 10.11 Exercise Speeds Up Pyruvate Oxidation in Muscle 10.12 The Citric Acid Cycle 10.13 Exercise Speeds Up the Citric Acid Cycle in Muscle 10.14 The Electron Transport Chain 10.15 Oxidative Phosphorylation 10.16 Energy Yield of the Electron Transport Chain 10.17 Energy Yield of Carbohydrate Oxidation 10.18 Exercise Speeds Up Oxidative Phosphorylation in Muscle 10.19 Lactate Production in Muscle During Exercise 10.20 Is Lactate Production a Cause of Fatigue? 10.21 Is Lactate Production Due to a Lack of Oxygen? 10.22 Features of the Anaerobic Carbohydrate Catabolism 10.23 Utilizing Lactate 10.24 Gluconeogenesis 10.25 A Shortcut in Gluconeogenesis 10.26 Exercise Speeds Up Gluconeogenesis in the Liver 10.27 The Cori Cycle 10.28 Exercise Speeds Up Glycogenolysis in the Liver 10.29 Control of the Plasma Glucose Concentration in Exercise 10.30 Blood Lactate Accumulation 10.31 Blood Lactate Decline 10.32 “Thresholds” Chapter 11. Lipid Metabolism in Exercise 11.1 Triacylglycerol Digestion, Absorption, and Distribution 11.2 Digestion, Absorption, and Distribution of Other Lipids 11.3 Fat Content of the Human Body 11.4 Triacylglycerol Synthesis in Adipose Tissue 11.5 Lipolysis 11.6 Exercise Speeds Up Lipolysis in Adipose Tissue 11.7 Exercise Speeds Up Lipolysis in Muscle 11.8 Fate of the Lipolytic Products During Exercise 11.9 Fatty Acid Degradation 11.10 Energy Yield of Fatty Acid Oxidation 11.11 Degradation of Unsaturated Fatty Acids 11.12 Degradation of Odd-Number Fatty Acids 11.13 Fatty Acid Synthesis 11.14 Synthesis of Fatty Acids Other Than Palmitate 11.15 Exercise Speeds Up Fatty Acid Oxidation in Muscle 11.16 Changes in the Plasma Fatty Acid Concentration and Profile During Exercise 11.17 Interconversion of Lipids and Carbohydrates 11.18 Brown Adipose Tissue 11.19 Plasma Lipoproteins 11.20 A Lipoprotein Odyssey 11.21 Effects of Exercise on Plasma Triacylglycerols 11.22 Effects of Exercise on Plasma Cholesterol 11.23 Exercise Increases Ketone Body Formation Chapter 12. Protein Metabolism in Exercise 12.1 Processing of Dietary Proteins 12.2 Protein Content of the Human Body 12.3 Protein Turnover 12.4 Effects of Exercise on Protein Turnover 12.5 Amino Acid Degradation 12.6 Amino Acid Synthesis 12.7 Effects of Exercise on Amino Acid Metabolism in Muscle 12.8 Effects of Exercise on Amino Acid Metabolism in the Liver 12.9 The Urea Cycle 12.6 Amino Acid Synthesis 12.10 Plasma Amino Acid, Ammonia, and Urea Concentrations During Exercise 12.11 Contribution of Proteins to the Energy Expenditure of Exercise 12.12 Effects of Training on Protein Turnover Chapter 13. Effects of Exercise on Gene Expression 13.1 Stages in the Control of Gene Expression 13.2 Stages in the Control of Gene Expression Affected by Exercise 13.3 Kinetics of a Gene Product After Exercise 13.4 Exercise-Induced Changes That May Modify Gene Expression 13.5 Mechanisms of Exercise-Induced Muscle Hypertrophy 13.6 Mechanisms of Exercise-Induced Increase in Muscle-Mitochondrial Content 13.7 Exercise and Epigenetics Chapter 14. Integration of Exercise Metabolism 14.1 Interconnections of Metabolic Pathways 14.2 Energy Systems 14.3 Energy Sources in Exercise 14.4 Choice of Energy Sources During Exercise 14.5 Effect of Exercise Intensity on the Choice of Energy Sources 14.6 Effect of Exercise Duration on the Choice of Energy Sources 14.7 Interplay of Duration and Intensity: Energy Sources in Running and Swimming 14.8 Effect of the Exercise Program on the Choice of Energy Sources 14.9 Sex Differences in the Choice of Energy Sources During Exercise 14.10 How Sex Influences the Choice of Energy Sources During Exercise 14.11 Effect of Age on the Choice of Energy Sources During Exercise 14.12 Effect of Carbohydrate Intake on the Choice of Energy Sources During Exercise 14.13 Effect of Fat Intake on the Choice of Energy Sources During Exercise 14.14 Adaptations of the Proportion of Energy Sources During Exercise to Endurance Training 14.15 How Endurance Training Modifies the Proportion of Energy Sources During Exercise? 14.16 Adaptations of Energy Metabolism to Resistance and Sprint Training 14.17 Adaptations of Exercise Metabolism to Interval Training 14.18 Effect of the Genome on the Choice of Energy Sources in Exercise 14.19 Muscle Fiber Type Transitions 14.20 Effects of Environmental Factors on the Choice of Energy Sources in Exercise 14.21 The Proportion of Fuels Can Be Measured Bloodlessly 14.22 Hormonal Effects on Exercise Metabolism 14.23 Redox State and Exercise Metabolism 14.24 Causes of Fatigue 14.25 Recovery of the Energy State After Exercise 14.26 Metabolic Changes in Detraining Chapter 15. Exercise to Fight Disease 15.1 Health, Disease, and Exercise 15.2 Exercise to Fight Cardiovascular Disease 15.3 Adaptations of the Heart to Training 15.4 Adaptations of the Vasculature to Training 15.5 Exercise to Fight Cancer 15.6 Diabetes, a Major Metabolic Upset 15.7 Exercise to Fight Diabetes 15.8 Obesity, a Health-Threatening Condition 15.9 Why Obesity Is Harmful 15.10 Exercise to Fight Obesity 15.11 Exercise to Fight Osteoporosis 15.12 Exercise to Fight Mental Dysfunction 15.13 The Detriments of Physical Inactivity 15.14 Exercise for Healthy Aging and Longevity 15.15 Benefits From Regular Exercise in Other Diseases 15.16 A Final Word on the Value of Exercise Part IV. Biochemical Assessment of Exercising Persons IV.1 The Blood IV.2 Aims and Scope of the Biochemical Assessment IV.3 The Reference Interval IV.4 Classes of Biochemical Parameters Chapter 16. Iron Status 16.1 Hemoglobin 16.2 Hematologic Parameters 16.3 Does Sports Anemia Exist? 16.4 Iron 16.5 Total Iron-Binding Capacity 16.6 Transferrin Saturation 16.7 Soluble Transferrin Receptor 16.8 Ferritin 16.9 Iron Deficiency Chapter 17. Metabolites 17.1 Lactate 17.2 Estimating the Anaerobic Lactic Capacity 17.3 Programming Training 17.4 Estimating Aerobic Endurance 17.5 Glucose 17.6 Triacylglycerols 17.7 Cholesterol 17.8 Recapping the Lipidemic Profile 17.9 Glycerol 17.10 Urea 17.11 Ammonia 17.12 Creatinine 17.13 Uric acid 17.14 Glutathione Chapter 18. Enzymes and Hormones 18.1 Enzymes 18.2 Creatine Kinase 18.3 Glutamyltransferase 18.4 Antioxidant Enzymes 18.5 Steroid Hormones 18.6 Cortisol 18.7 Testosterone 18.8 Overtraining Syndrome 18.9 Epilogue Part IV Summary

    £91.80

  • Handbook of Phytonutrients in Indigenous Fruits

    CABI Publishing Handbook of Phytonutrients in Indigenous Fruits

    Book SynopsisThe effects of inadequate diets on the population include malnutrition, non-communicable diseases and obesity. 'Hidden hunger', also known as micronutrient deficiencies, leads to various health-related disorders and diseases. Indigenous plants, in the form of indigenous fruits and leafy vegetables are gaining interest as a source of nutrients and bioactive phytochemicals, satisfying both food demand and health needs. Moreover, with the impact of climate change, and the importance of sustainability of food systems, it is essential that we investigate new, forgotten and alternative crops that can thrive in harsh conditions, require low fertilizer input, and are easily harvestable.This book contains chapters on 33 understudied indigenous fruits and vegetables from all around the world, including African nightshade, amaranth, baobab fruit, Indian gooseberry, red bush apple and snake melon. Each chapter provides:An overview of plant botany.An understanding of the phytonutrient constituents and health-promoting properties of bioactive compounds or metabolites.Information on the biological activity of the functional compounds that will improve productivity and increase utilization of indigenous fruits and vegetables to sustain food security.Impacts of postharvest storage, processing, and traditional food preparation methods.Potential for new product development.This is an essential resource for academic researchers and industry professionals in the fields of horticulture, agriculture, crop science, human health and nutrition.

    £140.40

  • Painless Biology

    Kaplan Publishing Painless Biology

    7 in stock

    Book SynopsisWhether you’re a student or an adult looking to refresh your knowledge, Barron’s Painless Biology provides review and practice in an easy, step-by-step format.An essential resource for: Virtual Learning Homeschool Learning pods Supplementing classes/in-person learning Inside you’ll find: Comprehensive coverage of biology, including, nature of science, cell anatomy, biochemistry, animals and plants, genetics, and much more Diagrams, charts, and instructive science illustrations Painless tips, common pitfalls, and informative sidebars Brain Tickler quizzes and answers throughout each chapter to test your progress

    7 in stock

    £11.69

  • Symphony in C

    HarperCollins Publishers Symphony in C

    Book SynopsisAn enchanting biography of the most resonant and most necessary chemical element on Earth.Carbon. It is the building block of every cell that makes up every living thing. It is the essential component of the food we eat, the fuel we burn, the wood we use and the air we breathe. It is worth billions as a luxury and half a trillion as a necessity, but there are still mysteries to be solved about the element that can be both diamond and coal. Where does it come from, what does it do, and why, above all, does life need it?In Symphony in C, leading carbon scientist Robert M. Hazen takes us on a vibrant journey through the origin and evolution of life's most widespread element. The story unfolds in four movements Earth, Air, Fire and Water and transports us through nearly 14 billion years of cosmic history, explaining how carbon is formed in the hearts of stars and why all life forms earthbound or alien use it as the basis of their biology. Symphony in C is a sweeping chronicle of carbTrade ReviewPraise for Symphony in C ‘A valuable and welcome explanation of why we would do well to pay more attention to the sixth element – and of how much more remains to be discovered about its planetary role through time’ Nature ‘Covering topics from carbon’s ancient origins to the threats that carbon compounds pose to our future climate, Hazen’s book is a fascinating read. Symphony in C chronicles cutting-edge science that’s helping researchers make better sense of the carbon-rich world around us’ Science News ‘From the Big Bang to coal, carbohydrates, and ultra-strong high-tech nanofibers, Robert M. Hazen provides an illuminating and enjoyable guide to the remarkable odyssey of carbon, the element of life. Enjoy the trip!’ Andrew Knoll, Fisher Professor of Natural History, Harvard University ‘C is the element carbon. C is a musical note. Scientist-musician Hazen uses the element and the note to compose a symphonic masterpiece that reveals how the primitive life that began on our planet four billion years ago has evolved into Darwin’s “endless forms most beautiful“’ David W. Deamer, author of Assembling Life ‘Hazen’s virtuoso performance captures the wonder of the sixth element – from volcanic gases to al dente pasta to life’s very beginnings – while telling the wonderful stories about the people behind the discoveries’ Terry Plank, Arthur D. Storke Memorial Professor of Geochemistry, Columbia University ‘This book is an incredibly rich story of carbon and its role in of life. Hazen has outdone himself in delivering an engaging, edifying, great read. If you don’t know why carbon is important in your life, or even if you think you do, you should put down whatever you’re reading and get this book’ Paul G. Falkowski, author of Life’s Engines``

    £11.69

  • Nutritional Biochemistry

    Elsevier Science Nutritional Biochemistry

    1 in stock

    Book SynopsisOffering a scientific approach to nutrition, this book describes the function of nutritional requirements at the cellular and molecular level. It includes a discussion of relevant aspects of physiology, food chemistry, toxicology, pediatrics, and public health.Table of ContentsClassification of Biological Structures Digestion and Absorption Nutrients that Resist or Escape Digestion Regulation of Energy Metabolism Energy Requirement Lipids Protein Vitamins Inorganic Nutrients Appendix A: Nutrition Methodology B: Cloning and Dot Blots

    1 in stock

    £93.09

  • Side Reactions in Peptide Synthesis

    Elsevier Science Side Reactions in Peptide Synthesis

    1 in stock

    Book SynopsisBased on the author's academic and industrial experience and backed by a thorough review of the literature, this book provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis.Table of ContentsPeptide Fragmentation/Deletion Premature FMOC Deprotection Elimination Side Reactions Peptide Global Deprotection/Scavenger-Induced Side Reactions Peptide Rearrangement Side Reactions Side Reactions Occurring at Amino Acid/Peptide Activation Step Intramolecular Cyclization Side Reactions Side Reactions in Amino Groups in Peptide Synthesis Side Reactions in Hydroxyl, Carboxyl, Ester Groups in Peptide Synthesis Oxidation and Reduction Side Reactions in Peptide Synthesis Racemization in Peptide Synthesis Solvent and Residual Impurities in the Reagents Induced Side Reactions Dipeptide Formation Side Reactions (Redundant Amino Acid Incorporation) Reattachment of Peptides to the Solid Supports Addition Side Reactions in Peptide Synthesis Side Reactions in Phosphor Peptides Side Reactions in CYS Protein Fragmentations

    1 in stock

    £66.59

  • Oxford Handbook of Medical Sciences

    Oxford University Press Oxford Handbook of Medical Sciences

    2 in stock

    Book SynopsisWritten by biomedical scientists and clinicians to disseminate the fundamental scientific principles that underpin clinical medicine, this new edition provides a clear, easily digestible account of basic cell physiology and biochemistry, and an investigation of the traditional piers of medicine.Trade ReviewReview from previous edition I have no doubt that OHMS is one of the best books I have ever bought. * Medical Student, University of Edinburgh *I would certainly recommend this book for clinical students who want to refresh some basic sciences later in their education. This is a reliable reference book which I think will serve me very well into my clinical years and I shall keep by my desk for those moments where I need to find a long-ago learnt and now-forgotten fact! * Cambridge Medicine Journal *This book represents excellent value for money and is a superb offering which is now in a mature third edition. * Dr Harry Brown, Pavilion Health Today *Table of Contents1: Cellular structure and function 2: Cellular metabolism 3: Molecular and medical genetics 4: Nerve and muscle 5: Musculoskeletal system 6: Respiratory and cardiovascular systems 7: Urinary system 8: Digestive system 9: Endocrine organs 10: Reproduction and development 11: Neuroanatomy and neurophysiology 12: Infection and immunity 13: Growth of tissues and organs 14: Medicine and society 15: Techniques of medical sciences

    2 in stock

    £32.29

  • Medical Genetics and Genomics

    Oxford University Press Medical Genetics and Genomics

    1 in stock

    Book Synopsis

    1 in stock

    £47.49

  • Biochemistry

    Oxford University Press Biochemistry

    1 in stock

    Book SynopsisWritten primarily for 16-19 year old students, this primer aims to extend students'' knowledge and inspire them to take their school-level learning further. It explores topics that are familiar from the curriculum and also introduces new ideas, giving students a first taste of the study of biology beyond school-level and demonstrating how concepts frequently encountered at school are relevant to and applied in current research. This is the ideal text to support students who are considering making the transition from studying biology at school to university. This is a concise, stimulating introduction to the fundamental biomolecules in cells and organisms, and the exciting ways biochemistry could be used to solve global problems, both now and in the future.Table of Contents1: Carbohydrates: Why life is sweet 2: Lipids and Proteins: the building blocks of a cell 3: Nucleotides and Nucleic Acids: Biology's information stores 4: Metabolism: Transforming energy and biomolecules 5: Maintaining a Metabolic Balance 6: Solving Tomorrow's Problems with Natural Products 7: Solving Tomorrow's Problems: Bioenergy and the environment

    1 in stock

    £29.60

  • A Primer on Stable Isotopes in Ecology

    Oxford University Press A Primer on Stable Isotopes in Ecology

    1 in stock

    Book SynopsisIn the past few decades, the field of ecology has made huge advancements thanks to stable isotopes. Ecologists need to understand the principles of stable isotopes to fully appreciate many studies in their discipline. Ecologists also need to be aware of isotopic approaches to enrich their toolbox for further advancing the discipline. A Primer on Stable Isotopes in Ecology is a concise and foundational resource for anyone interested in acquiring theoretical and practical knowledge for the application of stable isotopes in ecology.Readers will gain a more in-depth and complete knowledge of stable isotopes and explore isotopic methods used in ecological research, learning about stable isotope definitions, measurement, ecological processes, and applications in research. Chapters include in-depth descriptions of stable isotopes and their notation, isotope fractionation, isotope mixing, heavy isotope enrichment, and quantification methods by mass spectrometry and laser spectroscopy. The textTable of Contents1: Stable isotopes as a tool for ecologists 2: Stable isotopes, notations, and standards 3: Isotopic fractionation 4: Isotope mixing 5: Heavy isotope enrichments 6: Measuring stable isotopes

    1 in stock

    £39.00

  • Mann J Essentials of Human Nutrition 6e

    Oxford University Press Mann J Essentials of Human Nutrition 6e

    3 in stock

    Book SynopsisEssentials of Human Nutrition provides a complete and student-friendly introduction to the field for those embarking on courses in nutrition, or related subjects, for the first time. Written by an international team of experts, every chapter is carefully edited to give consistently clear and coherent explanations of all of the essential principles of nutrition. Key Features BL Chapters cover a broad range of disciplines to help students develop a complete understanding of the subject.BL Inter-chapter links help students see connections between different topics and build up a coherent picture of the subject as a whole.BL The text explains the impact of nutritional principles applied in practice, for example, in the context of sports and health care.New to this EditionThis sixth edition has been updated to incorporate new research and emerging topics such as biomarkers, assessment of nutritional status, and binge-eating disorders. Digital Formats and ResourcesEssentials of Human Nutrition is available for students and institutions to purchase in a variety of formats, and is supported by online resources.BL The e-book offers a mobile experience and convenient access: www.oxfordtextbooks.co.uk/ebooksBL Lecturer resources BL Image bankTrade ReviewReview from previous edition A great introduction to basic nutrition, diet, factors influencing dietary choice, dietary needs through the life course, and a taster of how diet and poor nutrition can be both a cause and a consequence of disease.An essential textbook for any introductory course in nutrition.A comprehensive, well written, and relevant textbook which provides an excellent overview of the current field of human nutrition.Table of ContentsPart 1: Introducing Human Nutrition 1: A. Stewart Truswell, Jim Mann, and Leanne Hodson: Introduction Part 2: Energy and Macronutrients 2: Jim Mann and Andrew Reynolds: Carbohydrates 3: C. Murray Skeaff, Jim Mann, and Leanne Hodson: Lipids 4: Colleen S. Deane, Daniel J. Wilkinson, and Philip J. Atherton: Protein 5: Andrew M. Prentice: Energy 6: A. Stewart Truswell: Alcohol Part 3: Organic and Inorganic Essential Nutrients 7: Lewis J. James and Gethin H. Evans: Water, Electrolytes, and Acid-base Balance 8: Helen Lambert, Ohood Hakim, and Susan A. Lanham-New: Major Minerals: Calcium and Magnesium 9: Patrick MacPhail: Iron 10: Samir Samman, Sheila Skeaff, Christine D. Thomson, and A. Stewart Truswell: Trace Elements 11: David I. Thurnham: Vitamin A and Carotenoids 12: A. Stewart Truswell: The B Vitamins 13: A. Stewart Truswell and Jim Mann: Vitamins C and E 14: A. Stewart Truswell: Vitamins D and K 15: Bernhard Watzl: Other Biologically Active Substances in Plant Foods: Phytochemicals 16: Anne-Marie Minihane: Nutrition, Genetics, and Personalized Nutrition Part 4: Nutrition-Related Disorders 17: Mike Lean: Overweight and Obesity 18: A. Stewart Truswell: Protein-Energy Malnutrition 19: Jim Mann and Rachael McLean: Cardiovascular Diseases 20: Kathryn E. Bradbury and Timothy J. Key: Nutrition and Cancer 21: Jim Mann: Diabetes Mellitus and the Metabolic Syndrome 22: Hannah Turner and Robert Peveler: The Eating Disorders: Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, and OSFED Part 5: Foods 23: Andrew Reynolds, A. Stewart Truswell, Margaret Allman-Farinelli, Meika Foster, Anna Rangan, Leanne Hodson, and Kim Bell-Anderson: Food Groups 24: Martijn B. Katan: Functional Foods and Health Claims 25: Peter Williams and Paul Brent: Food Toxicity and Safety Part 6: Changing Food Habits 26: A. Stewart Truswell and Helen Leach: Food Habits 27: A. Stewart Truswell, Leanne Hodson, and Jim Mann: Nutritional Recommendations for the General Population 28: Susan A. Jebb: Public Health Approaches to Implement Dietary Recommendations 29: C. Murray Skeaff: Dietary Patterns 30: Wilma Waterlander and Boyd Swinburn: Food Systems: Challenges and Ways Forward 31: Tim Lang and Pamela Mason: Nutrition, the Environment, and Sustainable Diets Part 7: Life Stages 32: Annie S. Anderson: Pre-Pregnancy, Pregnancy, and Lactation 33: Anne-Louise Heath, Helen Crawley, and Rachael Taylor: Infant Feeding and Eating Well for Toddlers 34: Rachael Taylor and Anne-Louise Heath: Childhood and Adolescent Nutrition 35: Sian Robinson and Clare Corish: Nutrition and Ageing Part 8: Nutritional Assessment 36: Philippa Lyons-Wall: Food Analysis, Food Composition Tables, and Databases 37: Jim Mann and Silke Morrison: Dietary Assessment 38: A. Stewart Truswell: Assessment of Nutritional Status 39: Nita G. Forouhi and Albert Koulman: Biomarkers Part 9: Applications 40: Louise M. Burke: Sports Nutrition 41: Claire Smith and Winsome R. Parnell: Nutritional Consequences of Poverty and Food Insecurity in Developed Countries 42: Suzie Ferrie: Food in Hospitals 43: Ross C. Smith: Nutritional Support for Hospital Patients

    3 in stock

    £67.62

  • Protein Structure and Function

    Oxford University Press Protein Structure and Function

    1 in stock

    Book SynopsisHow does the chemical description of a protein relate to its three-dimensional structure? How does the three-dimensional structure relate to the machinery that brings about a chemical reaction? How does the sequence of a gene encode not only the sequence of a protein but, more importantly, the architecture and function of that protein?Protein Structure and Function provides a clear and critical survey of our current understanding of the structure and function of proteins to answer questions such as these. Opening with a consideration of the link between protein sequence and structure, it goes on to explore the structural basis of protein function and how this function is controlled. Finally, it examines a range of case studies that illuminate the range of roles performed by proteins, and the diverse structures these proteins exhibit.Protein Structure and Function combines articulate prose with striking full colour illustrations, while the unique Primers in Biology modular structure intTrade ReviewA really good book provides a wealth of information in a manner that the reader remembers what he/she has read. This book does just that. The contents just pop into mind from time to time. This book will be a winner. * Tom Bruice, University of California, Santa Barbara *This treatment and focus is much needed. It will be essential reading by students and faculty alike, and will serve as a crucial reference book for everyone in the biosciences. * James Spudich, Stanford University School of Medicine *It is well-written, makes for interesting reading and contains a number of excellent examples. The whole book appears to be an important, useful and timely one. * Roman Laskowski, European Bioinformatics Institute *Table of Contents1. From Sequence to Structure ; 2. From Structure to Function ; 3. Control of Protein Function ; 4. From Sequence to Function: Case Studies in Structural and Functional Genomics ; 5. Structure Determination

    1 in stock

    £66.49

  • Cell Signalling

    Oxford University Press Cell Signalling

    1 in stock

    Book SynopsisSignalling within and between cells is one of the most important aspects of modern biochemistry and cell biology. An understanding of signalling pathways is vital to a wide range of biologists, from those who are investigating the causes of cancer, to those who are concerned about the impact of environmental pollutants on the ecosystem. The way cells adapt to changing environments, and the way cell dysfunction causes disease, is underpinned by cell signalling events. Cell Signalling presents a carefully structured and highly accessible introduction to this intricate and rapidly growing field. Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms, before examining how these components come together to create signalling pathways. A focus on common components and concepts, rather than mechanistic detail, allows the reader to gain a thorough understanding of the principles that underpin cell signalling. Online Resource CentreThe Online Resource Centre to accompany Cell Signalling features:For students:- Links to useful websitesFor registered adopters of the text:- Journal Clubs: suggested research papers and discussion questions linked to topics featured in the book- Figures from the book in electronic format for use in lecturesTrade ReviewA good overview of the key underlying concepts and principles, allowing students to gain a solid grounding in the subject. I like the Case Study sections which link to research findings; these provide relevant context and help students to understand the key message in complex scientific articles. * Dr Andrew Chantry, University of East Anglia *It is really the best specialist text for undergraduates on this topic I have seen. * Dr Fergus Doherty, University of Nottingham *Review from previous edition: John Hancock's Cell Signalling is a straightforward introduction to a rapidly expanding field of biology. Its unintimidating writing style, simple and uncluttered figures, and competitive price make it a wonderful introductory text for undergraduates. * Dr Laura K. Palmer, Penn State University *Review from previous edition: Complexity and specificity are the hallmarks of cell signalling, yet Hancock in this third edition has gone a long way to simplify these complicated processes. His signalling examples are clever and well-conceived, his writing descriptive and his passion for his subject infectious ... this is marvellous value for money and is a worthy companion to an undergraduate/postgraduate reference library. * John P. Phelan, Waterford Institute of Technology, Ireland in The Biochemist *Table of ContentsPART 1: AN OVERVIEW OF SIGNALLING; PART 2: COMPONENTS THAT COMPRISE SIGNALLING PATHWAYS; PART 3: SELECTED EXAMPLES OF SIGNALLING PATHWAYS AND EVENTS; PART 4: FINAL THOUGHTS

    1 in stock

    £52.99

  • Beer

    Oxford University Press Inc Beer

    1 in stock

    Book SynopsisDespite competition from an ever-growing range of alternative adult beverages, beer remains a vastly important beverage globally. There is a huge diversity of beer styles, drinks suited not only to refreshment and delight in themselves, but also to suit any drinking occasion, including alongside food of all types. There is nutritional value in beer and evidence that, consumed responsibly, it can be a valuable part of a well-balanced diet. This relates to the wholesomeness of the basic materials employed for the brewing of beer, notably malt and hops, but also the nature of the longstanding processes that are employed in converting cereals such as barley and wheat into malt and thence through the time-honored stages of brewing. This book explains these issues- history, nature and complexity of the modern brewing business, types of beer, quality attributes of beer, the underpinning processes, and much more. Any reader, from those who know little about the subject through to the beer aficTrade ReviewThis book is a good read for anyone interested in the science of beer or its consumption." -Chemistry WorldTable of ContentsForeword by Dr Tim Cooper Preface Preface to the Third Edition Preface to the Second Edition Preface to the First Edition Acknowledgments Introduction Chapter 1: FERTILE CRESCENT TO FRANKFURT: The World of Beer and Breweries Chapter 2: A BRIEF HISTORY OF BEER Chapter 3: BARLEY TO BARREL: The Basics of Malting and Brewing Chapter 4: PERSONAL CHOICE: Beer Styles Chapter 5: SEE, SMELL, SAVOR: The Quality of Beer Chapter 6: BEER AND BODY Chapter 7: THE HEART AND SOUL OF BEER: Malt Chapter 8: WATER: And Genuine Terroir Chapter 9: RICE, CORN AND OTHER TOUCHY SUBJECTS Chapter 10: THE WICKED AND PERNICIOUS WEED: Hops Chapter 11: HOT STUFF: The Brewhouse Chapter 12: GODESGOOD: Yeast and Fermentation Chapter 13: REFINING MATTERS: Downstream Processing Chapter 14: ENVIRONMENTAL MATTERS Chapter 15: MEASURE FOR MEASURE: How Beer Is Analyzed Chapter 16: REVERENCE FOR BEER Chapter 17: TO THE FUTURE: Malting and Brewing in Years to Come Glossary Further Study Index

    1 in stock

    £19.99

  • Dietary Reference Intakes A Risk Assessment Model for Establishing Upper Intake Levels for Nutrients Compass Series

    National Academies Press Dietary Reference Intakes A Risk Assessment Model for Establishing Upper Intake Levels for Nutrients Compass Series

    1 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    1 in stock

    £58.65

  • The 2nd International Forum on Biosecurity

    National Academies Press The 2nd International Forum on Biosecurity

    1 in stock

    Book SynopsisCovers the discussions of the 2nd International Forum on Biosecurity, held in Budapest, Hungary on March 30-April 2, 2008.Table of Contents1 Front Matter; 2 1 Background; 3 2 Plenary and Working Group Presentations and Discussions; 4 3 Major Themes and Next Steps; 5 References; 6 Appendixes; 7 Appendix A: Committee Member Biographies; 8 Appendix B: Agenda; 9 Appendix C: Examples of Projects and Initiatives

    1 in stock

    £42.00

  • The Science and Applications of Microbial Genomics

    National Academies Press The Science and Applications of Microbial Genomics

    1 in stock

    Table of Contents1 Front Matter; 2 Workshop Overview; 3 Appendix A; 4 Appendix B--Agenda; 5 Appendix C--Acronyms; 6 Appendix D--Glossary; 7 Appendix E--Speaker Biographies

    1 in stock

    £52.00

  • Clinical Biochemistry

    Elsevier - Health Sciences Division Clinical Biochemistry

    1 in stock

    Book SynopsisTable of ContentsPreface to the sixth edition Preface to the seventh edition Acknowledgements Part 1: Introducing clinical biochemistry 1 The clinical biochemistry laboratory 2 The use of the laboratory 3 Interpretation of results: general 4 Interpretation of results: diagnosis 5 Interpretation of results: monitoring 6 Analytical aspects Part 2: Core biochemistry 7 Fluid and electrolytes: basic concepts 8 Water and sodium balance: physiological mechanisms 9 Hyponatraemia: pathophysiology 10 Hyponatraemia: assessment and management 11 Hypernatraemia 12 Hyperkalaemia 13 Hypokalaemia 14 Intravenous fluid therapy 15 Investigation of renal function (1) 16 Investigation of renal function (2) 17 Urinalysis 18 Proteinuria 19 Acute kidney injury 20 Chronic kidney disease 21 Acid-base: concepts and vocabulary 22 Metabolic acid-base disorders 23 Respiratory and mixed acid-base disorders 24 Acid-base disorders: diagnosis and management 25 Proteins and enzymes 26 Immunoglobulins 27 Myocardial infarction 28 Liver function tests 29 Jaundice 30 Liver disease 31 Glucose metabolism and diabetes mellitus 32 Diagnosis and monitoring of diabetes mellitus 33 Diabetic ketoacidosis 34 Hypoglycaemia 35 Calcium regulation and hypocalcaemia 36 Hypercalcaemia 37 Phosphate and magnesium 38 Metabolic bone disease 39 Osteoporosis and fragility fractures Part 3: Endocrinology 40 Endocrine control 41 Dynamic function tests 42 Pituitary function 43 Growth disorders and acromegaly 44 Thyroid pathophysiology 45 Hypothyroidism 46 Hyperthyroidism 47 Adrenocortical pathophysiology 48 Hypofunction of the adrenal cortex 49 Hyperfunction of the adrenal cortex 50 Gonadal function 51 Subfertility Part 4: Specialised investigations 52 Nutritional assessment 53 Nutritional support 54 Parenteral nutrition 55 The metabolic response to injury 56 Gastrointestinal disorders 57 Disorders of the pancreas 58 Iron 59 Zinc and copper 60 Therapeutic drug monitoring 61 Toxicology 62 Metal poisoning 63 Alcohol 64 Ascites 65 Pleural fluid 66 Cerebrospinal fluid 67 Identification of body fluids 68 Lipoprotein metabolism 69 Clinical disorders of lipid metabolism 70 Hypertension 71 Cancer and its consequences 72 Tumour markers 73 Multiple endocrine neoplasia 74 Hyperuricaemia 75 Myopathy 76 Fetal monitoring and prenatal diagnosis 77 Pregnancy 78 Antenatal screening 79 Screening the newborn for disease 80 Paediatric biochemistry 81 Inborn errors of metabolism 82 Methods involving antibodies: immunoassay 83 Methods to separate and identify molecules 84 Selected inherited disorders Case history comments Index

    1 in stock

    £34.19

  • Biochemistry

    Cengage Learning, Inc Biochemistry

    1 in stock

    Book SynopsisIdeal for readers encountering biochemistry for the first time, Garrett and Grisham's BIOCHEMISTRY, Seventh Edition, makes even complex course concepts more accessible while revealing the beauty and usefulness of biochemistry in the everyday world. This engaging text illuminates the fundamental principles governing the structure, function and interactions of biological molecules, providing a solid foundation in biochemistry whether you are an undergraduate majoring in life sciences, chemistry or premedical programs, or a medical or graduate health sciences student seeking a deeper understanding of human physiology. Updated to reflect tremendous recent developments in biochemistry, the Seventh Edition features new and revised material and presentations throughout the text, incorporating additional content while maintaining a balanced and streamlined presentation. In addition, the authors emphasize the interrelationships of ideas to help you appreciate the overarching questions of biocheTable of ContentsPart I: MOLECULAR COMPONENTS OF CELLS. 1. The Facts of Life: Chemistry is the Logic of Biological Phenomena 1. 2. Water: The Medium of Life. 3. Thermodynamics of Biological Systems. 4. Amino Acids and the Peptide Bond. 5. Proteins: Their Primary Structure and Biological Functions. 6. Proteins: Secondary, Tertiary and Quaternary Structure. 7. Carbohydrates and the Glycoconjugates of Cell Surfaces. 8. Lipids. 9. Membranes and Membrane Transport. 10. Nucleotides and Nucleic Acids. 11. Structure of Nucleic Acids. 12. Recombination, Cloning, Gene Editing and Synthetic Biology--An Introduction. Part II: PROTEIN DYNAMICS. 13. Enzymes--Kinetics and Specificity. 14. Mechanisms of Enzyme Action. 15. Enzyme Regulation. 16. Molecular Motors. Part III: METABOLISM AND ITS REGULATION. 17. Metabolism: An Overview. 18. Glycolysis. 19. The Tricarboxylic Acid Cycle. 20. Electron Transport and Oxidative Phosphorylation. 21. Photosynthesis. 22. Gluconeogenesis, Glycogen Metabolism and the Pentose Phosphate Pathway. 23. Fatty Acid Catabolism. 24. Lipid Biosynthesis. 25. Nitrogen Acquisition and Amino Acid Metabolism. 26. Synthesis and Degradation of Nucleotides. 27. Metabolic Integration and Organ Specialization. Part IV: INFORMATION TRANSFER. 28. DNA Metabolism: Replication, Recombination and Repair. 29. Transcription and the Regulation of Gene Expression. 30. Protein Synthesis. 31. Completing the Protein Life Cycle: Folding, Processing and Degradation. 32. The Reception and Transmission of Extracellular Information.

    1 in stock

    £76.99

  • Introduction to Nutrition and Metabolism

    Taylor & Francis Ltd Introduction to Nutrition and Metabolism

    15 in stock

    Book SynopsisIntroduction to Nutrition and Metabolism equips readers with an understanding of the scientific basis of what we call a healthy diet. Now in its sixth edition, this highly recognized textbook provides clear explanations of how nutrients are metabolized and gives the principles of biochemistry needed for comprehending the science of nutrition.This full-color textbook explores the need for food and the uses to which food is put in the body, as well as the interactions between health and diet. Outlining the scientific basis behind nutritional requirements and recommendations, this new edition has been extensively revised to reflect current knowledge.Features: Lists key objectives at the beginning, and summary points at the end of each chapter. Accompanying online resources include interactive tutorial exercises based on interpretation of clinical and research data. Covers topics including: Chemical reactions and catalysis by enzymes; the role ofTrade Review Amy Hess Fischl, MS RDN LDN BC-ADM CDCES(University of Chicago Medical Center) **Description** This sixth edition of a primer of nutritional biochemistry, coming seven years after the last edition, builds on previous content to include key emerging areas of nutrition research, specifically the gut microbiome and epigenetics.*Purpose** The purpose is to enable readers to gain a working knowledge of how nutrients are metabolized and how they influence our metabolic status since these boiling blocks of knowledge are key to our relationship with food. Nutritional biochemistry is crucial to our understanding of the scientific basis behind eating principles. The book meets these objectives.**Audience** The book is written for "those using this information in their studies," which I consider to be nutrition students and nutrition practitioners. The book meets the needs of this audience. The lead author has been part of this book since the first edition. The second author also appears to be a credible authority as a nutrition lecturer and professor.**Features** The eleven chapters cover the key topics in nutritional biochemistry: micronutrients, enzymes and metabolic pathways, the role of ATP, digestion and absorption, metabolism of the macronutrients. The first chapter also delves into why we eat and spends a little time discussing religion, cultural differences, availability, and social status, which is a practical way to lay the framework for the information the book provides. The chapter on diet and health adds nutrition genomics to the conversation as well. While the book is laden with key content, the lead author also provides an additional resource on a website he controls called "The Virtual Tutorial." This has interactive exercises to help readers understand the metabolism of energy, carbohydrate, lipids, and protein. The author suggests that the exercises can be completed alone or in a group "gathered around the same computer." While the website is not formally part of the book, it does appear that it would be helpful for readers to test their knowledge in a more tangible way.**Assessment** This book is a perfectly acceptable option for students who are required to take a nutritional biochemistry course. Given the time between editions, this update is justified.--Weighted Numerical Score: 73 - 3 Stars Table of Contents Contents Preface .......................................................................................................................................... xvii Authors .......................................................................................................................................... xix Additional Resources on the Website: Metabolism Online – The Virtual Tutorial ........................ xxi Chapter 1 Why Eat? ..................................................................................................................... 1 Chapter 2 Enzymes and Metabolic Pathways ...................................................................... 21 Chapter 3 The Role of ATP in Metabolism .......................................................................... 53 Chapter 4 Digestion and Absorption .................................................................................... 83 Chapter 5 Energy Nutrition: The Metabolism of Carbohydrates and Fats .................. 121 Chapter 6 Diet and Health: Nutrition and Chronic Noncommunicable Diseases …. 1 73 Chapter 7 Overweight and Obesity ..................................................................................... 223 Chapter 8 Protein- Energy Malnutrition: Problems of Undernutrition ......................... 247 Chapter 9 Protein Nutrition and Metabolism ................................................................... 259 Chapter 10 The Integration and Control of Metabolism ................................................... 293 Chapter 11 Micronutrients: The Vitamins and Minerals .................................................. 323 Index ............................................................................................................................................. 421

    15 in stock

    £68.99

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