Description
Book SynopsisBased on the author's academic and industrial experience and backed by a thorough review of the literature, this book provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis.
Table of ContentsPeptide Fragmentation/Deletion Premature FMOC Deprotection Elimination Side Reactions Peptide Global Deprotection/Scavenger-Induced Side Reactions Peptide Rearrangement Side Reactions Side Reactions Occurring at Amino Acid/Peptide Activation Step Intramolecular Cyclization Side Reactions Side Reactions in Amino Groups in Peptide Synthesis Side Reactions in Hydroxyl, Carboxyl, Ester Groups in Peptide Synthesis Oxidation and Reduction Side Reactions in Peptide Synthesis Racemization in Peptide Synthesis Solvent and Residual Impurities in the Reagents Induced Side Reactions Dipeptide Formation Side Reactions (Redundant Amino Acid Incorporation) Reattachment of Peptides to the Solid Supports Addition Side Reactions in Peptide Synthesis Side Reactions in Phosphor Peptides Side Reactions in CYS Protein Fragmentations
