Medical research Books
Springer Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair
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Springer Liver and Pancreatic Diseases Management
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Springer The Arterial Chemoreceptors
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Springer Cd137 Pathway Immunology and Diseases
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Springer Taurine 6
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Springer Immediate Early Genes in Sensory Processing Cognitive Performance and Neurological Disorders
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Springer Java for Bioinformatics and Biomedical Applications
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Springer Molecularly Targeted Therapy for Childhood Cancer
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Springer Data Mining in Biomedicine 7 Springer Optimization and Its Applications
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Springer Whos Who in Fluorescence 2007
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Springer Genetically Engineered Mice for Cancer Research Design Analysis Pathways Validation and PreClinical Testing
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Springer Osteoimmunology
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Springer Principles of Bacterial Detection Biosensors Recognition Receptors and Microsystems
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Springer Hypoxia and the Circulation
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Springer Brain Development in Drosophila melanogaster
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Springer Molecular Mechanisms of Parasite Invasion
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Springer Bacterial Signal Transduction Networks and Drug Targets
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Springer Biomarkers for Psychiatric Disorders
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Springer The Sarcomere and Skeletal Muscle Disease
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Springer New York Molecular Radiation Biology The Action Of Ionizing Radiation On Elementary Biological Objects Heidelberg Science Library
Table of Contents1. Introduction.- 1.1. Historical Survey.- 1.2. Dose-Response Curves and Special Aspects of Radiation Action.- 1.3. The Temporal Stages of Radiation Action.- 1.4. The Significance of Molecular Radiation Biology.- 1.5. An Introduction to Molecular Radiation Biology.- References.- 2. The Hit Theory.- 2.1. Basic Concepts.- 2.2. Single and Multiple Hit Phenomena.- 2.3. Dose-Response Curves of Multiple Target Systems.- 2.4. The Influence of Biological Variability on the Form of Dose-Response Curves.- 2.5. The “Relative Steepness” of the Dose-Response Curve.- 2.6. Possibilities of Deception by Single-Hit Curves.- References.- 3. The Stochastics of the Action of Radiation.- 3.1. Kinetic Interpretation of the Dose-Response Curve.- 3.2. Multi-Hit Curves.- 3.3. Reverse Processes.- 3.4. A Formalistic Description of Dose-Response Curves.- 3.5. Dose-Response Curves of Colony Formation.- References.- 4. Primary Processes of Energy Absorption.- 4.1. X- and Gamma-Radiation.- 4.2. Neutrons.- 4.3. Charged Particles.- 4.4. Uptake of Energy by Molecules.- 4.5. The Energy Distribution of Secondary Electrons.- 4.6. Energy Deposited per Primary Interaction.- References.- 5. Target Theory and Action Cross Section.- 5.1. Establishment of a Rigid Concept of a “Hit”.- 5.2. Target Theory.- 5.3. Theory of the Action Cross Section.- 5.4. Relative Biological Effectiveness.- References.- 6. Direct and Indirect Action of Radiation.- 6.1. The Direct Effect.- 6.2. Indirect Effect in Solutions.- 6.3. Indirect Effect in Cells.- 6.4. Indirect Effect in the Dry State.- 6.5. Protective and Sensitizing Agents.- References.- 7. The Temperature Effect.- 7.1. Experimental Observations.- 7.2. Temperature Effect and the Indirect Action of Radiation..- 7.3. LET-Dependence of the Temperature Effect.- 7.4. The “Thermal Spike” Model.- References.- 8. The Oxygen Effect.- 8.1. The Oxygen Effect in Macromolecules.- 8.2. An Oxygen Effect Hypothesis.- 8.3. The Oxygen Effect in Bacteria.- 8.4. Oxygen Effect and LET.- References.- 9. The Action of Radiation on Enzymes: The Example of Ribonuclease.- 9.1. Structure and Function of Ribonuclease.- 9.2. Inactivation Kinetics.- 9.3. Radiation-Induced Radicals.- 9.4. Changes in Irradiated Enzyme Molecules.- 9.5. Separation and Identification of Irradiation Products.- 9.6. Amino Acid Analysis.- 9.7. Mechanisms of Inactivation.- References.- 10. Physico-Chemical Changes in Irradiated Nucleic Acids.- 10.1. The Structure of DNA.- 10.2. Radiation-Induced Radicals.- 10.3. Chemical Changes in Irradiated DNA.- 10.4. Breaks in the Polynucleotide Chains.- 10.5. Intermolecular Cross-Linking.- 10.6. Rupture of Hydrogen Bonds.- References.- 11. Inactivation of Nucleic Acid Functions.- 11.1. Functions of Nucleic Acids.- 11.2. Infectivity.- 11.3. Transformation.- 11.4. Priming Activity of DNA.- 11.5. Enzyme Induction.- 11.6. DNA-mRNA Hybrids.- 11.7. Translation.- References.- 12. The Action of Radiation on Viruses.- 12.1. Basic Properties of Viruses.- 12.2. Inactivation of Viruses containing Single-Stranded Nucleic Acids.- 12.3. Inactivation of Viruses containing Double-Stranded DNA.- 12.4. Repair of Radiation Damage in Viral DNA.- 12.5. BU Effect.- References.- 13. The Action of Radiation on Bacteria.- 13.1. Some Basic Properties of Bacteria.- 13.2. Inactivation of Bacteria.- 13.3. Bacterial DNA as the Critical Target.- 13.4. Repair of UV Damage.- 13.5. Repair of Damage caused by Ionizing Radiation.- 13.6. Genetic Control of Repair in Bacterium E. coli.- 13.7. Micrococcus Radiodurans.- References.- 14. Radiation Sensitivity and Biological Complexity.- 14.1. Attempts at a Systematic Approach.- 14.2. What is Radiation Sensitivity?.- References.
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Springer TripleHelical Nucleic Acids
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Springer Introduction to Molecular Medicine
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Springer Cellular and Molecular Methods in Neuroscience Research
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Springer Human Body Dynamics Classical Mechanics and Human Movement
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Springer Listen to the Music
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Springer Fixation in Histochemistry
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Springer Food Preparation Spaces The Shape of space
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Springer Project Leadership
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iUniverse Searching the Web for Health A Guide to Finding Reliable Medical Information on the Internet
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iUniverse A Life in Academic Medicine
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Kidneyhood.Org Stopping Kidney Disease
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Springer The Importance of Animal Experimentation for Safety and Biomedical Research
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Springer Biomedical Light Microscopy
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Springer In vitro Diagnostic Medical Devices Law and Practice in Five EU Member States
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Springer Manual of Biological Markers of Disease
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Springer Laboratory Techniques in Thrombosis a Manual
Book SynopsisThe first edition of this manual appeared in 1992 and was entitled ECAT Assay Procedures. It was the result of a unique cooperation between experts brought together by the European Concerted Action on Thrombosis and Disabilities (ECAT). The Concerted Action was at that time under the auspices of the Commission of the European Union. The second edition, like the first edition, deals with diagnostic tests within the field of thrombosis. However, the second edition has a broader scope because it is no longer limited by the frontiers of ECAT. Experts allover the world, in and outside ECAT, have contributed to this edition. The editors are very grateful for their contributions. The need for a new edition is obvious. Since 1992 new assays have been introduced for research, diagnosis, and therapy of thrombosis; for other assays improvements have been suggested, while a few others becameTrade Review`The objective towards standardization is largely met, since world experts on each assay collaborated to evaluate and compare the available methodologies and point to the advantages and disadvantages of each one. This book is written for clinical thrombosis and hemostasis laboratorians. Another attractive feature is the degree of expertise recruited to produce these critical summaries of existing methodologies. This book is a long overdue update of the first edition in view of the multitude of newly developed methodologies and the number of manufacturers involved.' Demetra D. Callas, Loyola University Medical Center in Doody Publishing Inc. Table of ContentsList of Contributors. Nomenclature of Haemostasis Factors. 1. Introduction to Laboratory Assays in Haemostasis and Thrombosis; J.Gram, J. Jespersen. 2. Good Medical Laboratory Services - Guidelines; J.-C. Libeer. 3. Blood Collection and Sample Preparation: Pre-analytical Variation; I.D. Walker. 4. Quality Assessment of Haemostatic Assays and External Quality Assessment Schemes; T.A.L. Woods, et al. 5. Activated Partial Thromboplastin Time (APTT); L. Poller. 6. Prothrombin Time (PT); L. Poller. 7. Endogenous Thrombin Potential; H.C. Hemker, S. Béguin. 8. Fibrinogen; M.P.M. de Maat, et al.9. Activated Factor VII; J.H. Morrissey. 10. Factor VII Activity and Antigen; G. Mariani, et al. 11. Factor VIII Clotting Activity; P.M. Mannucci, A. Tripodi. 12. Von Willebrand Factor; P.M. Mannucci, R. Coppola. 13. Antithrombin Activity and Antigen; J. Conard. 14. Protein C Activity and Antigen; R.M. Bertina. 15. Protein S Antigen; R.M. Bertina. 16. Protein S Activity Assays; E.M. Faioni. 17. Activated Protein C (APC) Resistance; A. Tripodi. 18. Tissue Factor Pathway Inhibitor (TFPI); P.M. Sandset. 19. Lupus Anticoagulant; D.A. Triplett. 20. Heparin Cofactor II; S.J. Bauman, F.C. Church. 21. Fibrinopeptide A (FPA); A. Haeberli. 22. Thrombin-Antithrombin (TAT) Complexes; J. Harenberg. 23. Prothrombin Fragment F 1+ 2; A. Haeberli. 24. Plasma Tissue-Type Plasminogen Activator (t-PA) Activity; C. Kluft, et al. 25. Tissue Type Plasminogen Activator Antigen (t-PA Ag); M.Ch. Alessi, I. Juhan-Vague. 26. Plasminogen Activator Inhibitor-1(PAI-1) Antigen; P.J. Declerk. 27. Plasminogen Activity; P.J. Gaffney. 28. Plasma Plasmin Inhibitor* Activity (*Previously &agr;2-Antiplasmin); C. Kluft, P. Meyer. 29. Plasmin-&agr;2-Antiplasmin Complexes (Plasmin-Plasmin Inhibitor Complexes); E. Hattey, et al. 30. Soluble Fibrin and Degradation Products of Fibrinogen (FgDP), Fibrin (FbDP;D-dimer) and Total of FgDP and FbDP (TDP); W. Nieuwenhuizen, R. Bos. 31. Venous Occlusion Test in Fibrinolysis Assays; J. Jespersen. 32. List of Manufacturers. Index.
£170.99
Springer Animal Cell Technology Basic Applied Aspects Proceedings of the Tenth Annual Meeting of the Japanese Association for Animal Cell Technology Nagoya November 58 1997
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Springer DNA Methods in Clinical Microbiology
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Springer Laboratory Techniques in Thrombosis A Manual ECAT Assay Procedures 2nd Revised Edition of Ecat Assay Procedures
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Springer Novel Frontiers in the Production of Compounds for Biomedical Use 1 Focus on Biotechnology
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Springer Liver Diseases Advances in Treatment and Prevention Falk Symposium 137
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Springer State of the Art of Hepatology Molecular and Cell Biology Falk Symposium 138
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Springer Portal Hypertension in the 21st Century The proceedings of a symposium sponsored by Axcan Pharma Inc and NicOx SA held in Montrl Canada April 24 2004
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Springer Gallstones Pathogenesis and Treatment Falk Symposium 139
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Springer Genitourinary Infections
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Springer The Immunoassay Kit Directory
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Springer In Situ Hybridization Medical Applications
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Penguin Random House LLC Its All in Your Head The Link Between Mercury Amalgams and Illness
Book SynopsisDescribes the dangers of using mercury in the amalgams used to fill teeth.
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