Health systems and services Books
F.A. Davis Company Modern Blood Banking Transfusion Practices
Book SynopsisJoin the generations of students who have embarked on successful careers with a firm foundation in the theory and practice of blood banking and transfusion practices. Denise Harmening's classic text teaches you not only how to perform must-know tests and tasks, but to understand the scientific principles behind them.Table of Contents Part I Fundamental Concepts 1. Red Blood Cell and Platelet Preservation: Historical Perspectives and Current Trends 2. Basic Genetics 3. Fundamentals of Immunology 4. Concepts in Molecular Biology Part II Blood Groups and Serological Testing 5. The Antiglobulin Test 6. The ABO Blood Group System 7. The Rh Blood Group System 8. Blood Group Terminology & Common Blood Groups: The Lewis System, P, I, MNS, Kell, Duffy, Kidd, Lutheran 9. Uncommon Blood Groups 10. Detection and Identification of Antibodies 11. Pre-transfusion Testing 12. Blood Bank Testing Technologies and Automation Part III Transfusion Practices 13. Donor Selection 14. Transfusion-Transmitted Diseases 15. Component Preparation 16. Transfusion Therapy 17. Adverse Effects of Blood Transfusion 18. Apheresis 19. Cellular Therapy in the Transplant Setting 20. Hemolytic Disease of the Fetus and Newborn 21. Autoimmune Hemolytic Anemias 22. Tissue Banking Part IV Leukocyte Antigens and Relationship Testing 23. The HLA System 24. Relationship Testing Part V Quality Management and Compliance 25. Quality Management in the Blood Bank 26. Patient Blood Management 27. Transfusion Safety and Federal Regulatory Requirements 28. Laboratory Information Systems in the Blood Bank 29. Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services
£109.80
F.A. Davis Company Urinalysis and Body Fluids
Book SynopsisSafely handle urine and body fluids. Process and analyse them effectively. This is a comprehensive and highly visual introduction to the theoretical knowledge and practical skills needed to safely handle and analyze non-blood body fluids.Table of Contents Atlas of Urine and Body Fluids Images Part One: Basic Principles 1. Safety and Quality Management 2. Urine and Body Fluid Analysis Automation 3. Introduction to Urinalysis 4. Renal Function Part Two: Urinalysis 5. Physical Examination of Urine 6. Chemical Examination of Urine 7. Microscopic Examination of Urine 8. Renal Disease 9. Urine Screening for Metabolic Disorders Part Three: Other Body Fluids 10. Cerebrospinal Fluid 11. Semen 12. Synovial Fluid 13. Serous Fluid 14. Bronchoalveolar Lavage Fluid 15. Amniotic Fluid 16. Fecal Analysis 17. Vaginal Secretions Answers to Study Questions, Case Studies, and Clinical Situations Abbreviations Glossary Index
£62.70
Stanford University Press Infectious Change
Book SynopsisTrade Review"In this defining ethnography of China's public health system and its complex relation to epidemics, Katherine Mason brilliantly describes health professionals, their struggles to be effective and ethical, the barriers they face, and how they animate the Chinese public health system as a lived reality. Infectious Change is an impressive contribution to both China studies and to medical anthropology!" -- Arthur Kleinman, Director * Harvard Asia Center *"Meticulously crafted, Infectious Change draws readers into the world of Chinese public health after SARS. Mason documents fundamentally different approaches to epidemic control among global, state, and local practitioners, including management of migratory populations, data collection, and ethics, arguing that global directives often stymie local efforts. This book elucidates why epidemic prevention everywhere must draw on local knowledge and practices." -- Margaret Lock * author of The Alzheimer Conundrum *"Infectious Change brings us for the first time before a hitherto unacknowledged consequence of the 2009 H1N1 crisis, and, at that, in one of the most epidemiologically critical regions of the globe today. It is this invaluable insight that should hold the attention not only of medical anthropologists but also of the wider global health community." -- Christos Lynteris * Medical Anthropology Quarterly *"This is an excellent, thought-provoking book, which will appeal to those with interests in contemporary China, medical anthropology, and histories of health and disease. It yields insights that will illuminate broader debates, such as those that pivot on the challenges inherent in promoting the "global" as a category in health." -- Robert Peckham * Bulletin of the History of Medicine *"Katherine Mason's book is an important contribution to the fields of Chinese studies and anthropology, joining a recent spate of excellent studies using the methods of anthropology to look at the intersections of public health, cultural practices and politics in China...Mason's book reminds us that implementing public health policy is never only about what is technically correct. It is about the cultural values and practices that govern relationships. It is also about understanding the power dynamics of the political system and generating the political will to construct an enabling environment and accountability mechanism to achieve it. In China, the tensions between centre and local are rarely resolved in favour of local and when new criteria for professional advancement are introduced, it results in the type of dysfunction so masterfully described by Mason." -- Joan Kaufman * China Quarterly *"In Infectious Change, Katherine A. Mason provides a captivating analysis of public health in China in the wake of SARS...Infectious Change is an insightful work that would be of interest to scholars of China and global health practitioners while also being accessible to a general academic reader. For China scholars, Mason makes a major contribution to the literature on public health." -- Emilio Dirlikov * Anthropological Quarterly *"Infectious Change presents a rich ethnographic account of how the Tianmai CDC works, how it would like to transform itself, and the barriers to doing so. It will make an excellent addition to courses on the anthropology of China or of global health because of the clarity of its ethnographic account and also because of the questions it opens up."––Elanah Uretsky, Asian MedicinTable of ContentsContents and Abstracts1Introduction chapter abstractThis chapter situates the reader in time and space and lays out the main arguments of the book. The author provides an overview of the recent history of public health in China, and describes the pseudonymous city of Tianmai. The author then suggests that due to key differences between professional responsibility as it is defined in the clinical and public health settings - particularly with regards to the aggregate nature of the public health "client" – a bifurcation of service and governance arose in Tianmai between a "common" being served and local populations being governed. The chapter lays out five "commons" that will be examined in the rest of the book: a civilized immigrant common, a professional common, a transnational scientific common, a global health common, and a global common. It also suggests that the Tianmai case can offer novel insights into the study of global health. 2City of Immigrants chapter abstractThis chapter takes a closer look at the immigrant city of Tianmai, and considers how the modern, cosmopolitan urban paradise that Tianmai's elites were trying to build included some and excluded others. In particular, the chapter examines the relationship – or lack thereof – between Tianmai's public health professionals and the city's enormous "floating population" of rural-to-urban migrants. The author shows how her interlocutors – former migrants themselves – refused to engage with migrant individuals, and actively maintained personal, moral, and professional boundaries between themselves and the floating population. This effectively divulged public health professionals of responsibility for the majority of the people who lived in their city and established them as "biological non-citizens" who had to be governed but could not be served. In doing this public health professionals worked to serve a civilized immigrant common of modern urban subjects that did not include the floating population. 3Relationships, Trust, and Truths chapter abstractThis chapter illustrates how the power to implement any given public health initiative in China was located within the webs of guanxi, or personal relationships, that public health professionals spun anew at the beginning of each project. Drawing on rich ethnographic description, the chapter takes the reader into the banqueting and other entertainment rituals that public health professionals engaged in almost daily in order to create and maintain these networks of reciprocal obligation and personalistic trust. The author then examines how a group of young, highly educated post-SARS reformers attempted to rid the public health system of guanxi, which they regarded as anti-scientific and akin to corruption. These reformers hoped to build a more transparent and reliable system of disease reporting and governance by establishing a professional common grounded in professionalized trust. 4Scientific Imaginaries chapter abstractThis chapter critically examines public health research and science in Tianmai. The author explores the efforts of Chinese public health professionals to advance their careers through scientific research, and discusses how in the wake of SARS, Chinese public health institutions dramatically increased their investments in scientific research – rendering publishable research a major focus of local public health work. Newly hired young people labored to produce the "quality" and "true" data that they associated with good science. They hoped that doing so would give them a chance to "develop themselves" as members of transnational scientific common, and to escape a local moral world that they felt was dominated by mimicry, deception, and instability. The chapter suggests that their approach to research provides a mirror through which public health researchers in other contexts could critically examine their own ethical practices, raising new questions about global research ethics. 5Pandemic Betrayals chapter abstractThis chapter provides an ethnographically rich eyewitness account of Tianmai's response to the 2009 H1N1 influenza pandemic, describing how public health professionals in Tianmai drew upon the lessons of SARS to mount what they thought would be an internationally lauded response to H1N1. In attempting to prove their pandemic preparedness capabilities and ensure a place among the global scientific elite, however, Tianmai's public health professionals instead found that their full admittance into a global health common and a global common remained elusive. The chapter discusses the professionals' difficulties in escaping their perceived status as a source, rather than a victim, of dangerous viruses; their use of disease control tactics that were portrayed abroad as excessive and unsophisticated; and their disappointment with the failure of their leaders and guanxi partners to act in the professional fashion that they had been trying to promote since SARS. 6Conclusion chapter abstractThe concluding chapter returns to the broader question of what professional responsibility can or should mean in public health and beyond, and asks how public health professionals in China could work to reconcile the "common" with the "population," and population needs with individual needs. The author uses the case of HIV/AIDS to examine the ways in which some public health professionals in Tianmai were experimenting with alternative interpretations of public health that broadened the boundaries of the common to allow in otherwise maligned groups, including rural migrants, gay men, and sex workers. The book ends by considering the implications of this ethnography for the study of public health – both local and global – more broadly.
£67.15
Rutgers University Press Beyond Slash Burn and Poison Transforming Breast Cancer Stories into Action
Book SynopsisBreast cancer is, for some, a personal struggle; for others, it is a disease posing scientific and environmental challenges; and for others it is a highly charged and politicized issue around which policy wars rage. This book recognises the overlapping relationship of all these realities.Trade ReviewBeyond Slash, Burn and Poison makes a great contribution to the emerging literature on the breast cancer movement. The facts and framework of this book powerfully demonstrate the ability of women's words to transform society, and point the way to a future in which breast cancer policy reflects the experiences of all women-and men-affected by the disease. -- Barbara Brenner * Executive Director of Breast Cancer Action *Beyond Slash, Burn and Poison frames a number of crucial perspectives on breast cancer in relation to femininity, privilege, sexuality, race, and the environment. -- Eve Kosofsky Sedgwick * author of Touching Feeling: Affect, Pedagogy, Performativity *This is an extremely useful and readable history of breast cancer writing framed within a larger feminist history.Diane Price Herndl, Iowa State University -- Diane Price Herndl * Iowa State University *
£26.99
MW - Rutgers University Press American Catholic Hospitals A Century of Changing Markets and Missions Critical Issues in Health and Medicine Series
a huge range and FREE tracked UK delivery on ALL orders.
£29.70
Rutgers University Press Embodied Politics Indigenous Migrant Activism
Book SynopsisArguing for a structurally competent approach to migrant health, Embodied Politics shows how efforts to promote indigenous health may actually reinforce the same social and political economic forces, namely structural racism and neoliberalism, that are undermining the health of indigenous Oaxacans in Mexico and the United States.Trade Review"Embodied Politics: Health Promotion in Indigenous Mexican Migrant Communities is timely, well-researched, and well-written. It was a pleasure to read and I look forward to using and recommending it in the future." -- Seth Holmes * author of Fresh Fruit, Broken Bodies: Migrant Farmworkers in the United States *"Embodied Politics: Health Promotion in Indigenous Mexican Migrant Communities is timely, well-researched, and well-written. It was a pleasure to read and I look forward to using and recommending it in the future." -- Seth Holmes * author of Fresh Fruit, Broken Bodies: Migrant Farmworkers in the United States *Table of ContentsPrefaceChapter 1 The Paradoxical Politics of Health PromotionChapter 2 Structural Violence, Migrant Activism, and Indigenous HealthChapter 3 The “Mexican Model” of Health: Examining the Travels and Translations of Health PromotionChapter 4 Números, Números, Números: Making Health Programs AccountableChapter 5 Cultural Sensitivity Training and the Cultural Politics of Teaching ToleranceChapter 6 La Lucha Sigue: Migrant Activism and the Ongoing Struggle to Promote Indigenous HealthAcknowledgmentsNotesIndex
£23.39
Rutgers University Press Embodied Politics Indigenous Migrant Activism
Book SynopsisArguing for a structurally competent approach to migrant health, Embodied Politics shows how efforts to promote indigenous health may actually reinforce the same social and political economic forces, namely structural racism and neoliberalism, that are undermining the health of indigenous Oaxacans in Mexico and the United States.Trade Review"Embodied Politics: Health Promotion in Indigenous Mexican Migrant Communities is timely, well-researched, and well-written. It was a pleasure to read and I look forward to using and recommending it in the future." -- Seth Holmes * author of Fresh Fruit, Broken Bodies: Migrant Farmworkers in the United States *"Embodied Politics: Health Promotion in Indigenous Mexican Migrant Communities is timely, well-researched, and well-written. It was a pleasure to read and I look forward to using and recommending it in the future." -- Seth Holmes * author of Fresh Fruit, Broken Bodies: Migrant Farmworkers in the United States *Table of ContentsPrefaceChapter 1 The Paradoxical Politics of Health PromotionChapter 2 Structural Violence, Migrant Activism, and Indigenous HealthChapter 3 The “Mexican Model” of Health: Examining the Travels and Translations of Health PromotionChapter 4 Números, Números, Números: Making Health Programs AccountableChapter 5 Cultural Sensitivity Training and the Cultural Politics of Teaching ToleranceChapter 6 La Lucha Sigue: Migrant Activism and the Ongoing Struggle to Promote Indigenous HealthAcknowledgmentsNotesIndex
£105.40
Rutgers University Press Chronic Failures Medical Anthropology Kidneys
Book SynopsisExplores Chronic Kidney Disease and the search for renal care lived out in the context of poverty, inequality and uneven welfare arrangements. Based on ethnographic research conducted in the state of Jalisco, this book documents the routes uninsured Mexican patients take in order to access resource intensive biotechnical treatments.Trade Review“Kierans offers an extraordinary portrait of the challenges underlying efforts to survive kidney failure in Mexico. 'Regimes of care' extend far beyond clinical interventions, incorporating (and insisting upon) the ongoing labors of kin, including the transport challenges of ongoing dialysis treatments, the oppressive cost of immunosuppressant drugs post-transplant, the limits of universal insurance and its bureaucratic burdens, and even the necessity of having a microwave at home. This beautifully written, thought-provoking work stands out as an important contribution to social scientists’ writings on the sociomedical dimensions of organ failure, healthcare disparities, and on the entanglement of suffering and hope.”— Lesley A. Sharp, author of The Transplant Imaginary "the book is sensitive to multiple theoretical lenses that unpack the rich ethnographic details in the local complex settings. It is a must-read for those interested in medical anthropology, clinical nephrology, science and technology studies, global health, and biomedical ethics as it shows how organ transplantation, a 'miracle' medicine of the twentieth century, actually exploits the poor."— Medical Anthropology Quarterly “Chronic Failures unfolds a chilling account of the pathological regimes of renal care in Jalisco, Mexico, written in taut prose that is at once theoretically incisive and full of telling ethnographic texture. Moving deftly across the specific and entangled relations of bodies, markets, and state, this book brilliantly weaves together clinical paper-work and polluted lake water, pharmaceutical tianguis and charitable billionaires, media scandals and a mysterious new form of chronic kidney failure into a compelling indictment of the mirage of biomedical salvation. Kierans lays bare how sickness itself is made into a form of consuming labor – one that more often produces hardship and harm rather than health.”— Megan Crowley-Matoka, author of Domesticating Organ Transplant: Familial Sacrifice and National Aspiration in MexicoTable of ContentsForeword by Lenore Manderson Prologue Introduction Encountering Regimes of Renal Care: The Crucible of Experience Chapter One Studying Regimes of Renal Care Chapter Two Biopolitics and the Analytics of a Population on the Move Chapter Three Labor: Producing Sickness and the State Chapter Four Brokering Healthcare: Paper-work, Negotiation and the Strategies of Navigation Chapter Five Exchange: Bodies as Sites for the Production of (Surplus) Value Chapter Six Transplant Scandals, the State and the ‘Multiple Problematics’ of Accountability Chapter Seven Political and Corporate Etiologies: Producing Disease Emergence and Disease Response Epilogue References
£29.70
Rutgers University Press Chronic Failures Kidneys Regimes of Care and the
Book SynopsisChronic Failures: Kidneys, Regimes of Care and the Mexican State is about Chronic Kidney Disease (CKD) and the relentless search for care within a context of poverty, inequality and uneven welfare arrangements. Documenting the routes taken to access care, the practices of patients without entitlement offer critical perspectives on state-market-healthcare relations.Trade Review“Chronic Failures unfolds a chilling account of the pathological regimes of renal care in Jalisco, Mexico, written in taut prose that is at once theoretically incisive and full of telling ethnographic texture. Moving deftly across the specific and entangled relations of bodies, markets, and state, this book brilliantly weaves together clinical paper-work and polluted lake water, pharmaceutical tianguis and charitable billionaires, media scandals and a mysterious new form of chronic kidney failure into a compelling indictment of the mirage of biomedical salvation. Kierans lays bare how sickness itself is made into a form of consuming labor – one that more often produces hardship and harm rather than health.” -- Megan Crowley-Matoka * author of Domesticating Organ Transplant: Familial Sacrifice and National Aspiration in Mexico *“Kierans offers an extraordinary portrait of the challenges underlying efforts to survive kidney failure in Mexico. 'Regimes of care' extend far beyond clinical interventions, incorporating (and insisting upon) the ongoing labors of kin, including the transport challenges of ongoing dialysis treatments, the oppressive cost of immunosuppressant drugs post-transplant, the limits of universal insurance and its bureaucratic burdens, and even the necessity of having a microwave at home. This beautifully written, thought-provoking work stands out as an important contribution to social scientists’ writings on the sociomedical dimensions of organ failure, healthcare disparities, and on the entanglement of suffering and hope.” -- Lesley A. Sharp * author of The Transplant Imaginary *"the book is sensitive to multiple theoretical lenses that unpack the rich ethnographic details in the local complex settings. It is a must-read for those interested in medical anthropology, clinical nephrology, science and technology studies, global health, and biomedical ethics as it shows how organ transplantation, a 'miracle' medicine of the twentieth century, actually exploits the poor." * Medical Anthropology Quarterly *Table of ContentsForeword by Lenore Manderson Prologue Introduction Encountering Regimes of Renal Care: The Crucible of Experience Chapter One Studying Regimes of Renal Care Chapter Two Biopolitics and the Analytics of a Population on the Move Chapter Three Labor: Producing Sickness and the State Chapter Four Brokering Healthcare: Paper-work, Negotiation and the Strategies of Navigation Chapter Five Exchange: Bodies as Sites for the Production of (Surplus) Value Chapter Six Transplant Scandals, the State and the ‘Multiple Problematics’ of Accountability Chapter Seven Political and Corporate Etiologies: Producing Disease Emergence and Disease Response Epilogue References
£105.40
University of Minnesota Press Imagining Illness Public Health and Visual
Book SynopsisAnalyzing the visual culture of public health from the nineteenth century to the present.Trade Review"Imagining Illness fills a significant gap in terms of the visual culture of public health...the images are abundant and beautifully reproduced by the press. Given that this book is devoted to the image, it is heartening to see them reproduced here with such detail and expertise." —International Journal of Communication Table of ContentsContents Acknowledgments Introduction. Toward a Visual Culture of Public Health: From Broadside to YouTube David Serlin I. Tracing the Visual Culture of Public Health Campaigns 1. Image and the Imaginary in Early Health Education: Wilbur Augustus Sawyer and the Hookworm Campaigns of Australia and Asia Lenore Manderson 2. Cultural Communication in Picturing Health: W.W. Peter and Public Health Campaigns in China, 1912-1926 Liping Bu 3. The Color of Money: Campaigning for Health in Black and White America Gregg Mitman 4. Empathy and Objectivity: Health Education Through Corporate Publicity Films Kirsten Ostherr II. Mapping a Visual Genealogy of Public Health 5. Contagion, Public Health, and the Visual Culture of Nineteenth-Century Skin Katherine Ott 6. Maps as Graphic Propaganda for Public Health Mark Monmonier 7. "Some One Sole Unique Advertisement": Public Health Posters in the Twentieth Century William H. Helfand 8. Nursing the Nation: The 1930s Public Health Nurse as Image and Icon Shawn Michelle Smith III. Building New Public Spheres for Public Health 9. Visual Imagery and Epidemics in the Twentieth Century Roger Cooter and Claudia Stein 10. The Image of the Child in Postwar British and U.S. Psychoanalysis Lisa Cartwright 11. Performing Live Surgery on Television and the Internet Since 1945 David Serlin 12. Imagining Mood Disorders as a Public Health Crisis Emily Martin Contributors Index
£19.79
John Wiley & Sons Good Practices in Health Financing
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£37.76
MP-WBK World Bank Group Publ Discovering the Real World Health Workers Career Choices and Early Work Experience in Ethiopia
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£24.65
MP-WBK World Bank Group Publ Making Health Financing Work for Poor People in Tanzania
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£21.80
Duke University Press AIDS TV
Book SynopsisTrade Review"Juhasz’s perspective as an academic, activist, and videomaker produces an analysis that combines broad social analysis and a culturally informed feminist politics with the work of producing AIDS video. AIDS TV challenges the standard disciplinary compartmentalizing of AIDS scholarship and service work and brings a welcome critical focus on a body of work often treated as purely educational, but not as art."—Paula Treichler, University of Illinois College of Medicine at Urbana-Champaign
£25.19
University of Pittsburgh Press US Experiment in Social Medicine The The Community Health Center Program 19651986 Contemporary Community Health
Book SynopsisThe first political history of the Community Health Center Program, the only federal experiment in social medicine. Sardell views the inherent political struggles, and the survival of the program on the condition that it only serve the poor.Trade ReviewAn excellent account of how a policy network that included buraucratic and congressional actors initiated and, with the gradual development of supportive interest group actors, was able to sustain the Neighborhood Community Health Center Program."" - Journal of Health Politics, Policy and Law
£38.95
Kregel Publications,U.S. Basic Questions on Healthcare What Should Good
Book Synopsis
£7.46
University of Missouri Press Harry S.Truman Versus the Medical Lobby
Book SynopsisThis text provides a historiography of the Truman administration as well as a history of public health. It details the road to comprehensive health care in the USA and the legislative victories and defeats that occurred during the Truman years.
£38.90
John Wiley & Sons Introduction to Reference Sources in the Health Sciences
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£95.25
Edward Elgar Publishing Ltd Innovation and Health Theory Methodology and
Book SynopsisInnovation and Health investigates both the origin and the diffusion of novelty in the field of health.Trade ReviewIn this thought provoking and insightful book, Thomas Grebel provides the contours of a novel theoretical framework allowing us to cope with the complex nature of the creation, diffusion and normative direction of innovations in the health sector. Multi-disciplinary in scope and rigorous in technical and appreciative analysis, this book makes a major contribution to our understanding of the evolution of knowledge in general and the dynamic and complex nature of medical innovations in particular. Anyone seriously interested in theoretical and normative groundwork for an evolutionary knowledge-based approach to health economics will have to stop and listen. --Kurt Dopfer, University of St Gallen, SwitzerlandTable of ContentsContents: Preface 1. Introduction 2. Change in Economics 3. Health Economics 4. Towards a Theory of Innovation in Health Economics 5. Knowledge Creation in Medicine 6. Network Evolution in Medicine 7. Technology Diffusion in Medicine 8. Conclusion Bibliography Index
£88.00
Boydell & Brewer Ltd Charity and the London Hospitals 18501898
Book SynopsisA study of the development of the hospital as a economic, medical and voluntary institution in the second half of the nineteenth century.By the 1890s Victorians assumed that London's hospitals were facing an endemic financial crisis which was so severe that some feared the state might have to intervene to support an ailing voluntary system: charity both underpinnedLondon's hospitals and proved insufficient to meet the ever-increasing cost of care, despite the ability of those running the hospitals to pick the pockets of the benevolent. Charity and the London Hospitals takes these themes to study the development of the hospital as an economic, medical, and voluntary institution in the second half of the nineteenth century. Drawing on a comparative study of hospital records, the author investigates how and why Victorians contributed to show that benevolence was rarely amenable to a single form or reason, moving on to argue that though it remained central to the hospitals' raison d'être, philanthropy's contribution was modified at a financial and administrative level as hospitals shifted from being philanthropic to medical institutions. Why this process occurred and the impact of professionalisation and scientific medicine are also assessed, as are the debates surrounding hospitals and the state at the end of the nineteenth century. KEIR WADDINGTON is Professor of History at Cardiff University.Trade ReviewFills an important gap... Instead of depicting the 'great' metropolitan establishments as heroic arenas for medical and surgical triumphs, the author allows us to see them as administratively contested and financially precarious establishments. * MEDICAL HISTORY *A much needed and comprehensive study of hospital finance in the nineteenth century... sets the agenda for future work. * LONDON JOURNAL *Table of ContentsIntroduction: philanthropy and the London hospitals The philanthropic imperative Paying for the sick poor Financial diversification: an explanation Charity and control: voluntarism and the management of the London hospitals Striving for influence: lay versus medical control State aid versus voluntarism Conclusion: 1898 and beyond
£24.69
MP-MTB University of Manitoba Press Medicares Histories Origins Omissions and
Book SynopsisMedicare is arguably Canada's most valued social program. As federally-supported medicare enters its second half-century, Medicare's Histories brings together leading social and health historians to reflect on the origins and evolution of medicare and the missed opportunities characterizing its past and present.Table of Contents Chapter 1 Chief Complaint: Physician Discontent with Canadian Medicare Chapter 2 Medicine in the “Muskeg Metropolis:” Health Service Transformation in Canadian Resource Towns, 1960-1975 Chapter 3 From Health Care Policy to Professional Politics: Medicare and Allied Health Professionals in Quebec, 1960-1990 Chapter 4 Did Medicare Make Nursing Work Invisible? Chapter 5 “One foot on each side of the border:” Dr Frederick Dodge Mott, Rural Health, and “Socialized” Medical Care in the United States and Canada, 1930s-1970s Chapter 6 What Was Socialized Medicine? Revisiting the Radical Pre-History of Medicare Chapter 7 Medicare vs. Medicine Chest: Court Challenges and Treaty Rights to Health Care Chapter 8 Mental Health and Medicare: Who Cares? Chapter 9 Medicare and Maternity: Historicizing Inequities in Women’s Health Chapter 10 Becoming Not a Stranger: Home care for rural elders in the age of Medicare Chapter 11 Medicare in Canada from a Disability Rights Perspective, Ontario c. 1975-1990 Chapter 12 Prevention or Cure: The Contested History of Public Health and Medicare, 1960-2018 Chapter 13 Medicare Unfinished: Pharmacare and Denticare
£25.56
American Pharmacists Association (APhA) Pharmacists Guide to PointOfCare Testing
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£45.60
Harvard Global Equity Initiative Household Spending and Impoverishment
Book Synopsis
£18.86
John Wiley & Sons Inc Race Ethnicity and Health A Public Health Reader
Book SynopsisRace, Ethnicity and Health, Second Edition,is a critical selection of hallmark articles that address health disparities in America. It effectively documents the need for equal treatment and equal health status for minorities. Intended as a resource for faculty and students in public health as well as the social sciences, it will be also be valuable to public health administrators and frontline staff who serve diverse racial and ethnic populations.The book bringstogether the best peer reviewed research literature from the leading scholars and faculty in this growing field, providing a historical and political context for the study of health, race, and ethnicity, with key findings on disparities in access, use, and quality. This volume also examines the role of health care providers in health disparities and discusses the issue of matching patients and doctors by race. New chapters cover: reflections on demographic changes in the US based on the current census; metrics and nomenclature for disparities; theories of genetic basis for disparities; the built environment; residential segregation; environmental health; occupational health; health disparities in integrated communities; Latino health; Asian populations; stress and health; physician/patient relationships; hospital treatment of minorities; the slavery hypertension hypothesis; geographic disparities; and intervention design. Table of ContentsSources xi The Editors xv The Authors xvii Introduction: The Ethnic Demographic Transition 1Thomas A. LaVeist Chapter 1 Defining Health and Health Care Disparities and Examining Disparities Across the Life Span 11Lydia A. Isaac Part 1 Historical and Political Considerations Chapter 2 The Color Line: Race Matters in the Elimination of Health Disparities 35Stephen B. Thomas Chapter 3 Health Care Disparities—Science, Politics, and Race 41M. Gregg Bloche Part 2 Conceptualizing Race and Ethnicity Chapter 4 Why Genes Don’t Count (for Racial Differences in Health) 49Alan H. Goodman Chapter 5 Using “Socially Assigned Race” to Probe White Advantages in Health Status 57Camara Phyllis Jones, Benedict I. Truman, Laurie D. Elam-Evans, Camille A. Jones, Clara Y. Jones, Ruth Jiles, Susan F. Rumisha, Geraldine S. Perry Part 3 Explaining Racial and Ethnic Disparities Psychosocial and Individual-Level Determinants 77 Chapter 6 Racism as a Stressor for African Americans: A Biopsychosocial Model 79Rodney Clark, Norman B. Anderson, Vernessa R. Clark, David R. Williams Chapter 7 A Systematic Review of Empirical Research on Self-Reported Racism and Health 105Yin Paradies Chapter 8 Stress, Coping, and Health Outcomes among African-Americans: A Review of the John Henryism Hypothesis 139Gary G. Bennett, Marcellus M. Merritt, John J. Sollers III, Christopher L. Edwards, Keith E. Whitfi eld, Dwayne T. Brandon, Reginald D. Tucker-Seeley Chapter 9 Race and Unhealthy Behaviors: Chronic Stress, the HPA Axis, and Physical and Mental Health Disparities over the Life Course 159James S. Jackson, Katherine M. Knight, Jane A. Rafferty Chapter 10 Epigenetics and the Embodiment of Race: Developmental Origins of U.S. Racial Disparities in Cardiovascular Health 175Christopher W. Kuzawa, Elizabeth Sweet The Effects of Culture 213 Chapter 11 Acculturation and Latino Health in the United States: A Review of the Literature and Its Sociopolitical Context 215Marielena Lara, Cristina Gamboa, M. Iya Kahramanian, Leo S. Morales, David E. Hayes Bautista Chapter 12 Measuring Culture: A Critical Review of Acculturation and Health in Asian Immigrant Populations 253Talya Salant, Diane S. Lauderdale Chapter 13 Racial Influences Associated with Weight-Related Beliefs in African American and Caucasian Women 291Christie Z. Malpede, Lori F. Greene, Stephanie L. Fitzpatrick, Wendy K. Jefferson, Richard M. Shewchuk, Monica L. Baskin, Jamy D. Ard Chapter 14 Adverse Pregnancy Outcomes: Differences Between U.S.- and Foreign-Born Women in Major U.S. Racial and Ethnic Groups 303Gopal K. Singh, Stella M. Yu Social Determinants 321 Chapter 15 Levels of Racism: A Theoretic Framework and a Gardener’s Tale 323Camara Phyllis Jones Chapter 16 Racial Residential Segregation: A Fundamental Cause of Racial Disparities in Health 331David R. Williams, Chiquita Collins Chapter 17 Life Course Theories of Race Disparities: A Comparison of the Cumulative Dis/Advantage Theory Perspective and the Weathering Hypothesis 355Roland J. Thorpe Jr., Jessica A. Kelley-Moore Chapter 18 U.S. Socioeconomic and Racial Differences in Health: Patterns and Explanations 375David R. Williams, Chiquita Collins Chapter 19 Exploring Health Disparities in Integrated Communities 419Thomas A. LaVeist Environmental Determinants 437 Chapter 20 Race/Ethnicity, the Social Environment, and Health 439Marsha Lillie-Blanton, Thomas A. LaVeist Chapter 21 Built Environments and Obesity in Disadvantaged Populations 455Gina S. Lovasi, Malo A. Hutson, Monica Guerra, Kathryn M. Neckerman Chapter 22 Health Risk and Inequitable Distribution of Liquor Stores in African American Neighborhoods 485Thomas A. LaVeist, John M. Wallace Jr. Chapter 23 Environmental Health Disparities: A Framework Integrating Psychosocial and Environmental Concepts 493Gilbert C. Gee, Devon C. Payne-Sturges Chapter 24 Sick and Tired of Being Sick and Tired: Scientifi c Evidence, Methods, and Research Implications for Racial and Ethnic Disparities in Occupational Health 523Linda Rae Murray Part 4 Health Services and Health System Effects Patients 539 Chapter 25 Attitudes About Racism, Medical Mistrust, and Satisfaction with Care Among African American and White Cardiac Patients 541Thomas A. LaVeist, Kim J. Nickerson, Janice V. Bowie Chapter 26 The Legacy of Tuskegee and Trust in Medical Care: Is Tuskegee Responsible for Race Differences in Mistrust of Medical Care? 557Dwayne T. Brandon, Lydia A. Isaac, Thomas A. LaVeist Chapter 27 Patient Race/Ethnicity and Quality of Patient–Physician Communication during Medical Visits 569Rachel L. Johnson, Debra Roter, Neil R. Powe, Lisa A. Cooper Providers 587 Chapter 28 Implicit Bias among Physicians and Its Prediction of Thrombolysis Decisions for Black and White Patients 589Alexander R. Green, Dana R. Carney, Daniel J. Pallin, Long H. Ngo, Kristal L. Raymond, Lisa I. Iezzoni, Mahzarin R. Banaji Chapter 29 The Effect of Patient Race and Socio-Economic Status on Physicians’ Perceptions of Patients 607Michelle van Ryn, Jane Burke Chapter 30 Ethnicity and Analgesic Practice 637Knox H. Todd, Christi Deaton, Anne P. D’Adamo, Leon Goe Chapter 31 The Effect of Race and Sex on Physicians’ Recommendations for Cardiac Catheterization 647Kevin A. Schulman, Jesse A. Berlin, William Harless, Jon F. Kerner, Shyrl Sistrunk, Bernard J. Gersh, Ross Dubé, Christopher K. Taleghani, Jennifer E. Burke, Sankey Williams, John M. Eisenberg, José J. Escarce System 665 Chapter 32 Advancing Health Disparities Research within the Health Care System: A Conceptual Framework 667Amy M. Kilbourne, Galen Switzer, Kelly Hyman, Megan Crowley-Matoka, Michael J. Fine Chapter 33 Linking Cultural Competence Training to Improved Health Outcomes: Perspectives from the Field 689Joseph R. Betancourt, Alexander R. Green Chapter 34 “We Don’t Carry That”—Failure of Pharmacies in Predominantly Nonwhite Neighborhoods to Stock Opioid Analgesics 697R. Sean Morrison, Sylvan Wallenstein, Dana K. Natale, Richard S. Senzel, Lo-Li Huang Chapter 35 Do Hospitals Provide Lower-Quality Care to Minorities than to Whites? 707Darrell J. Gaskin, Christine S. Spencer, Patrick Richard, Gerard F. Anderson, Neil R. Powe, Thomas A. LaVeist Part 5 Health Disparities Solutions Chapter 36 Linking Science and Policy through Community-Based Participatory Research to Study and Address Health Disparities 723Meredith Minkler Chapter 37 The National Health Plan Collaborative to Reduce Disparities and Improve Quality 741Nicole Lurie, Allen Fremont, Stephen A. Somers, Kathryn Coltin, Andrea Gelzer, Rhonda Johnson, Wayne Rawlins, Grace Ting, Winston Wong, Donna Zimmerman Chapter 38 Interventions to Reduce Racial and Ethnic Disparities in Health Care 761Marshall H. Chin, Amy E. Walters, Scott C. Cook, Elbert S. Huang Index 787
£76.46
John Wiley and Sons Ltd Transplant Administration
Book SynopsisCovers the specifics of each aspect of transplant administration, providing information that will enable new administrators to quickly master essentials, help more seasoned administrators evaluate and improve their programs, and provide a knowledge base, focused on best-practices in light of regulatory requirements.Table of ContentsList of Contributors, vii Preface, xi Acknowledgments, xv About the Companion Website, xvii 1 Organ Allocation: NOTA, the OPTN, and Policy Development, 1 Kenneth Andreoni and Ciara Samana 2 Organizational Structures, 17 Lisa Norris 3 Human Resources, 27 Lisa Norris 4 Clinical Services, 39 Lisa Norris 5 Regulatory and Compliance Issues, 51 Marguerite Brown 6 Transplant Finance, 75 Lisa Norris 7 Managed Care Contracting, 97 Mindy Scharlin 8 Quality Assessment and Performance Improvement, 115 Lisa Norris 9 Transplant Information Management and Transplant Information Systems, 129 Lauren E. Kearns 10 Strategy and Marketing, 155 Lisa Norris 11 Managing and Leading the Transplant Enterprise, 171 Lisa Norris Appendix 1 Human Resources: Lists of Transplant Staff Duties, 181 Appendix 2 Human Resources: Medical/Surgical Director Job Description, 191 Appendix 3 Human Resources: In-Patient Transplant Coordinator Orientation, 195 Appendix 4 Human Resources: Post-Transplant Coordinator Orientation, 199 Appendix 5 Human Resources: Pre-Transplant Coordinator Orientation, 201 Appendix 6 Human Resources: Transplant Social Work Orientation, 203 Appendix 7 Regulatory and Compliance Issues: Surveyor Worksheet—Organ Transplant Program Quality Assessment and Performance Improvement, 207 Appendix 8 Transplant Finance: Kidney Organ Procurement Rates for 2013, 217 Appendix 9 Managed Care Contracting: UNOS RFI Example, 219 Appendix 10 Managed Care Contracting: Sample Letter to Claims Department, 223 Appendix 11 Managed Care Contracting: Sample Managed Care Contract, 225 Appendix 12 Insurance Approval Form, 229 Index, 231
£121.46
John Wiley and Sons Ltd Practice Development Workbook for Nursing Health
Book SynopsisIf you re looking to develop and improve your nursing, health or social care practice, either individually or as part of a team, the Practice Development Workbook for Nursing, Health and Social Care Teams offers a wide-ranging selection of activities, tools and resources covering vital aspects of practice development.Table of ContentsPreface ix About the companion website xi 1 Introduction: Getting the best out of this resource 1 Introduction 1 This resource matters because 4 Who is it for? 5 How can this resource be used in your workplace? 7 What is practice development? 9 The principles of practice development work 11 The person-centred practice framework 12 Useful websites and resources 14 2 Knowing and demonstrating values and beliefs about person-centred care 17 Introduction 17 Reflection on my own values and beliefs about the care/services I give or receive 20 Going for a reflective walk on your own or with someone else 21 Values and beliefs of the care setting 23 Leaders’ values and beliefs 25 Sheet 2.1: Worksheet for recording learning activities with a buddy: Values and beliefs about care 27 Sheet 2.2: Discussion groups 28 Discussion trigger 2.1: Short videos 30 Quick evaluation to raise profile of values and beliefs in the care home (available on companion website) Invitation and information sheet for patients/residents, families and care staff for the values and beliefs clarification activity (available on companion website) Discussion trigger 2.2: Posters (available on companion website) Discussion trigger 2.3: Factsheets (available on companion website) Discussion trigger 2.4: Scenarios (available on companion website) Discussion trigger 2.5: Scenarios created by sensory walkabouts (available on companion website) Discussion trigger 2.6: Accessing group/team values and beliefs through emotional triggers (available on companion website) Sheet 2.3: Handout: How to feature values and beliefs in your work around the care setting/care home 32 Sheet 2.4: Values and beliefs template 33 Sheet 2.5: Values and beliefs clarification activity: A facilitator’s guide (This section also includes materials that are on the companion website) 34 Sheet 2.6: Instruction sheet for patients/residents, families and care staff for the values and beliefs clarification activity 38 3 Developing a shared vision for person-centred care 39 Introduction 39 Guide: Setting up a practice development coordinating group for visioning activities 43 Sheet 3.1: Templates for group meeting agendas and notes 44 Sheet 3.2: Group relaxation activity (available on companion website) 45 Sheet 3.3: Creative methods for developing a shared vision: Programme of three workshops (you decide which one you might do) 45 Sheet 3.4: Workshop guidance: Visualisation through painting and/or collage 46 Sheet 3.5: Workshop guidance: Creating and sharing personal visions 48 Sheet 3.6: Workshop guidance: Vision statement development 50 Sheet 3.7: Guide: Visioning with a virtual group 51 Sheet 3.8: Questionnaire: Developing a shared vision for person-centred care at 52 Sheet 3.9: Visioning the practice development processes and developing ground rules (one-to-one) 53 Sheet 3.10: Visioning the practice development processes and developing ground rules (small informal group) 55 Sheet 3.11: Workshop guidance: Visioning the practice development processes and developing ground rules 57 Sheet 3.12: What do we do next? 58 Useful websites and resources 59 4 Introduction to measuring progress and evaluation 60 Introduction: Why measuring and evaluation is important 60 Workshop guidance: Current evaluation methods within your organisation 63 Trigger for group discussion: What are ‘metrics’ and how do we measure person-centred care? 65 Trigger for group discussion: Practice development principles for measuring and evaluation 66 Learning activity for teams: Evaluating care plans 67 Learning activity for teams: Evaluating your respect for dignity, privacy and the control people have in your service 70 Learning activity for teams: Cats, skirts, handbags and lipstick 73 ‘At a Glance’: Summary plan for personalised care (available on companion website) Learning activity for staff who serve food & drink: Evaluating the service you offer 74 Learning activity for housekeepers: Evaluating the cleaning, housekeeping or repair service you offer 76 Learning activity for team or home managers and those with an interest in learning and practice development: Evaluating the learning support systems for care teams 79 Guide: Reflection tools 82 Reflection tools and examples (available on companion website) Getting the commitment of stakeholders 84 Template for developing a communication plan with stakeholders 85 Guide: Setting up and sustaining a practice development coordinating group 86 Examples of session plans (available on companion website) Developing a common vision about our roles (available on companion website) Claims, Concerns and Issues: An evaluation tool for working with stakeholders 87 A template for stakeholders’ views: Claims, Concerns and Issues 88 An example of Claims, Concerns and Issues (1) 89 An example of Claims, Concerns and Issues (2) 90 Guide: Facilitating Claims, Concerns and Issues 91 5 Getting started together: Measuring and evaluating where we are now 93 Introduction 93 Guidance on developing evaluation questions 95 SWOT or TOWS tool 96 Forcefield analysis 97 Gathering evidence in the workplace 98 Example of a poster/flyer about gathering evidence (available on companion website) Example of a poster/information sheet about carrying out observations (available on companion website) Example of information sheet for families/decision makers of people for whom process consent might apply (e.g. people with severe cognitive impairment) (available on companion website) Guide: Method and documentation of consent process for individuals with severely impaired capacity (available on companion website) Giving and receiving feedback after evidence has been gathered 100 Workplace observations: Walkabout guide 102 Workplace observations: In a fixed place 103 Workplace observations: Record sheet 104 Combined observations: Record sheet for feedback 105 Guide: Observations of care 106 Guide: Patient/resident/relative narrative interview 106 Guide: Conversation with patients/residents with severe cognitive impairment 108 Two person-centred assessment tools (available on companion website) Handout: Culture 111 Method for facilitating a workshop on workplace culture (available on companion website) Handout: Effective workplace culture 112 Useful websites and resources 113 6 A practice development plan 114 Introduction 114 Pulling it together activity 1: Individual/informal group activity for analysis of evidence (in preparation for action planning) 119 Pulling it together workshop 1: Analysis of evidence gathered through observations, narratives and conversations 122 Pulling it together workshop 2: Comparing findings and interpretations 124 Worksheet for recording learning about person-centred care through practice development activities and workshops (available on companion website) Pulling it together activity 2: Individual/informal group activity for identifying indicators to prioritise action planning 127 Pulling it together workshop 3: Identifying indicators and using them to prioritise action planning 129 Practice development coordinating group: Roles and responsibilities 132 Person-centred practice templates (also available on companion website) 133 Evidence summary and action plan for aims and goals based on the person-centred practice framework 134 Overview action planning guide 138 Overview action planning template (available on companion website) Action point planning sheet (available on companion website) SMART and SMARTER goals 139 7 Mini-projects: Ongoing and integrated action, evaluation, learning and planning 140 Introduction 140 Examples of mini-projects 143 Mini-projects: Guide to structure and processes 145 Sheet 7.1: Leading a project/working/action or learning group 148 Sheet 7.2: Mini-project action planning template 149 Sheet 7.3: Example: Filled in mini-project action planning template 155 What do you do with this next? 161 8 Learning in the workplace 162 Introduction 162 Part 1: Creating a person-centred learning environment 167 Sheet 8.1: A learning culture guide 168 A framework for work-based learning (available on companion website) Sheet 8.2: Activity and guidance for managers for creating a person-centred learning environment 171 Sheet 8.3: Evaluation and process review of group work and sessions 174 Sheet 8.4: Giving and receiving feedback handout 176 Indicators of effective feedback (available on companion website) Indicators of ineffective feedback (available on companion website) Part 2: Active learning 178 Enabling questions 179 Activity 8.1: The 15 minute reflection space 181 Activity 8.2: Practising the use of open enabling questions in active learning 182 Sheet 8.5: Preparation for activities 3–6 184 Activity 8.3: Reflection on ‘self as active learner’ 185 Activity 8.4: Types/modes of reflection: The way you tend to reflect (available on companion website) Activity 8.5: Positive incident accounts 186 Activity 8.6: Problem-solving tool (available on companion website) Sheet 8.6: Worksheet for recording learning and action points 187 Sheet 8.7: Process evaluation: Listening critically to other peoples’ work 188 Sheet 8.8: Process evaluation record: Listening skills 189 Sheet 8.9: Process evaluation record: What I said 190 Sheet 8.10: Active learning evaluation 191 Part 3: Learning supervision 192 Induction programmes, preceptorship, mentorship, coaching and work-based learning facilitation 193 Guide for work-based facilitators: Foundation Degrees (available on companion website) Clinical or professional supervision for the future 195 Summary of learning in the workplace 195 Useful websites 196 Sharing and celebrating 9 What if ? When things don’t go so well 199 Introduction 199 Frequently asked questions 201 Most common challenges 207 Identifying why things are not going well 212 Sheet 9.1: Material from other chapters in this resource that can be used for addressing things that don’t go well 213 Activity 9.1: Acknowledging our own part in what didn’t go well 215 Activity 9.2: Helping each other learn from what didn’t go well and work out what to do about it 216 Activity 9.3: Acknowledging, in the working day, when things don’t go well and affirming plans to change 221 10 Practice development as a continuous process 223 Introduction 223 Activity 10.1: Look after yourself and your health 224 Activity 10.2: Keeping it fresh everyday 225 Guidance: Keeping practice development fresh 226 Examples: The art of re-invention 227 Activity 10.3: The art of re-invention 227 Linking to new policy agendas 229 Useful websites and resources 230 References 231 Index 233
£33.20
John Wiley & Sons Inc Promising Care
Book SynopsisPromising Care: How We Can Rescue Health Care by Improving It collects 16 speeches given over a period of 10 years by Donald M. Berwick, an internationally acclaimed champion of health care improvement throughout the course of his long and storied career as a physician, health care educator and policy expert, leader of the Institute for Healthcare Improvement (IHI), and administrator of the Centers for Medicare & Medicaid Services. These landmark speeches (including all of Berwick''s speeches delivered at IHI''s annual National Forum on Quality Improvement in Health Care from 2003 to 2012) clearly show why our medical systems don''t reliably contribute to our overall health. As a remedy he offers a vision for making our systems better safer, more effective, more efficient, and more humane. Each of Berwick''s compelling speeches is preceded by a brief commentary by a prominent figure in health care, policy, or politics who has a unique connection to that particular speTable of ContentsPreface ix Acknowledgments xiii The Author xv The Commentary Authors xvii Introduction xxviiby Maureen Bisognano 1 My Right Knee 1Commentary by Gary S. Kaplan 2 Some is Not a Number, Soon is Not a Time 25Commentary by C. Joseph McCannon 3 Power 45Commentary by Dale Ann Micalizzi 4 Mont Sainte-Victoire 67Commentary by Jason Leitch 5 A Message for Ramesh 89Commentary by Paul Farmer 6 Eating Soup with a Fork 101Commentary by Paul B. Batalden 7 What “Patient-Centered” Should Mean: Confessions of an Extremist 123Commentary by Frederick S. Southwick 8 Tense 137Commentary by Jessica Berwick 9 A Transatlantic Review of the NHS at Sixty 155Commentary by Lord Nigel Crisp 10 The Epitaph of Profession 165Commentary by Christine K. Cassel 11 Squirrel 177Commentary by Diana Chapman Walsh 12 You Decide 195Commentary by Beverley H. Johnson 13 The Moral Test 205Commentary by Tom Daschle 14 New Health System—New Professionalism 223Commentary by James Reason 15 To Isaiah 235Commentary by Mark D. Smith 16 And We Said, “No” 245Commentary by Patricia A. Gabow Index 267
£40.80
John Wiley & Sons Inc Fundamentals of Health Care Financial Management
Book SynopsisLearn the essentials of finance theory and practice with the tools needed in day-to-day practice In this thoroughly revised and updated fourth edition of Fundamentals of Health Care Financial Management, consultant and educator Steven Berger offers a practical step-by-step approach to understanding the fundamental theories and relationships guiding financial decisions in health care organization. Using cases set in a fictional mid-sized hospital, the book takes the reader into the inner workings of the finance executive''s office. As in the previous editions, this book introduces students to key practical concepts in fundamental areas of financial management. This innovative introduction to the most-used tools and techniques includes health care accounting and financial statements; managing cash, billings and collections; making major capital investments; determining cost and using cost information in decision-making; budgeting and performance measurement; and Table of ContentsFigures, Tables, and Exhibits vii Preface xv Acknowledgments xix The Author xxi Chapter 1: January 1 What Is Health Care? 3 What Is Management? 5 What Is Financial Management? 6 Why Is Financial Management Important? 8 Ridgeland Heights Medical Center: The Primary Statistics 9 Pro Forma Development 13 Living with the Finance Committee and Board of Directors’ Calendar 19 Year-End Closing 24 Chapter 2: February 31 Accounting Principles and Practices 32 Objectives of Financial Reporting 34 Basic Accounting Concepts 35 Basic Financial Statements of a Health Care Organization 36 Uses of Financial Information 37 The Financial Statements 39 Preparing for the Auditors 52 Analysis of Sensitive Accounts 54 February Finance Committee Special Reports 56 Chapter 3: March 61 Strategic Financial Planning: Five-Year Projections 63 RHMC Strategic Financial Planning 67 Ratio Analysis 74 The Capital Plan and Its Relationship to the Strategic Plan 84 Chapter 4: April 91 Medicare and Medicaid Net Revenue Concepts 94 Calculation of Medicare and Medicaid Contractual Adjustments 100 Implications of the Balanced Budget Act of 1997 109 Implications of the Medicare Modernization Act of 2003 115 Implications of the Patient Protection and Affordable Care Act of 2010 (PPACA or ACA) 117 Managed Care Net Revenue Concepts 131 Preparation of the Medicare and Medicaid Cost Report 137 Presentation of the Audited Financial Statements to the Finance Committee 140 Chapter 5: May 145 Fundamentals of Revenue Cycle Management (RCM) 146 Calculation of the Allowance for Doubtful Accounts and Bad-Debt Expense 165 Calculation of the Allowance for Contractual Adjustments 170 Chapter 6: June 175 Budget Preparation: The Beginning 177 Budget Calendar 177 Volume Issues 185 Capital Budgeting: June 190 Accounting and Finance Department Responsibilities 195 June Finance Committee Special Agenda Items 198 Chapter 7: July 203 Budget Preparation: The Middle Months 204 Capital Budgeting: July 221 Regulatory and Legal Environment 223 Other Regulatory and Business Compliance Issues 227 Corporate Compliance 228 Accreditation Issues 229 Patient Satisfaction Issues 232 Chapter 8: August 235 Capital Budget: August 236 Operating Budget 246 Budget Variance Analysis 249 Budget Variance Parameters 252 Flexible Budgeting 252 August Finance Committee Special Agenda Items 260 Chapter 9: September 263 Operating Budget 265 Capital Budget: September 275 Cash Budget 277 Physician Practice Management Issues 280 Current Physician Practice Issues—2013 292 Additional Physician-Hospital Integration Issues 294 Monthly Physician Reporting 295 Chapter 10: October 299 Information Systems Implications for Health Care Financial Management 301 Information Technology Strategic Plan Initiatives 304 HIPAA Implementation Issues 306 Selection of a New Health Care Information System 310 Budget Presentation to the Board Finance Committee 316 October Finance Committee Special Agenda Items 328 Chapter 11: November 331 Preparation of the Budget Results and Delivery to the Department Managers 333 Budgeting and Spreading Contractual Adjustments by Department 337 Issues Involving RHMC’s Cost Structure 340 How to Improve the Organization’s Cost Structure 344 Supply Chain Management in Health Care 352 Benefits of Tax Status for Health Care Organizations 356 Preparation and Implications of the Annual IRS 990 Report 360 Chapter 12: December 367 Getting Ready for Year-End Reporting—Again 371 Open-Heart Surgery Pro Forma 371 December Finance Committee Special Agenda Items 380 Looking into the Future of Health Care Finance 383 Future Conclusions 397 References 401 Index 407
£81.86
John Wiley and Sons Ltd Hand Hygiene
Book SynopsisThe first comprehensive, authoritative review of one of the most fundamental and important issues in infection control and patient safety, hand hygiene. Developed and presented by the world''s leading scholar-clinicians, Hand Hygiene is an essential resource for all medical professionals. Developed and presented by the world leaders in this fundamental topic Fully integrates World Health Organization (WHO) guidelines and policies Offers a global perspective in tackling hand hygiene issues in developed and developing countries Coverage of basic and highly complex clinical applications of hand hygiene practices Includes novel and unusual aspects and issues in hand hygiene such as religious and cultural aspects and patient participation Offers guidance at the individual, institutional, and organizational levels for national and worldwide hygiene promotion campaigns Trade Review"In their new textbook, Hand Hygiene: A Handbook for Medical Professionals, Didier Pittet, John Boyce, and Benedetta Allegranzi turn to leading experts on patient safety and infection control to produce an impressive book with 45 chapters focusing on every aspect of hand hygiene. But, as Pittet asks in the preface, “Does hand hygiene deserve a textbook?” It is refreshing for a textbook writer to ask this question about his own book, and the answer, as the foreword suggests, is a resounding “yes.”While hand hygiene is essential, compliance is complicated. Additionally, actual rates of compliance are difficult to measure as are the number of HAIs that can be prevented with high hand hygiene compliance rates. With these issues in mind, Pittet and colleagues present this new work with a noble objective, “to save many more millions of lives every year worldwide.”The edition includes many important, but often overlooked, areas in chapters covering topics such as handhygiene promotion strategies, human factors, barriers to compliance, and skin reaction to hand hygiene. Ofparticular importance, the book includes chapters on the safety climate as well as personal accountability. Of note, a chapter on religion and cultural practices sheds light on interesting issues that are often marginalised. The book is organised logically, beginning with a review of the data on HAI......We have a real problem with hand hygiene among medical professionals, and now is the time to embrace change. This handbook takes an important step in that direction. Pittet believes that a renewed commitment by providers will “drive excellence in hand hygiene practices, research, and attitudes for many years to come.” The editors and authors should be commended for this laudable goal and outstanding handbook" (The Lancet Vol 17 August 17)"This well-written book, coupled with its excellent editing, is easy to read. It succeeds in appealing to a diverse population of healthcare professionals. All healthcare facility leaders in patient safety and infection prevention would be well served by this guide and reference to improving hand hygiene" Doodys, Sept 2017Table of ContentsContributors xi Preface xv Foreword xvii 1. The Burden of Healthcare-Associated Infection 1Benedetta Allegranzi, Sepideh Bagheri Nejad, and Didier Pittet 2. Historical Perspectives 8Andrew J. Stewardson and Didier Pittet 3. Flora and Physiology of Normal Skin 12Gürkan Kaya and Didier Pittet 4. Dynamics of Hand Transmission 18Andrew J. Stewardson, Benedetta Allegranzi, and Didier Pittet 5. Mathematical Models of Handborne Transmission of Nosocomial Pathogens 28Ben S. Cooper and Nantasit Luangasanatip 6. Methodological Issues in Hand Hygiene Science 36Matthew Samore and Stephan Harbarth 7. Statistical Issues: How to Overcome the Complexity of Data Analysis in Hand Hygiene Research? 42Angèle Gayet-Ageron and Eli Perencevich 8. Hand Hygiene Agents 51Pascal Bonnabry and Andreas Voss 9. Methods to Evaluate the Antimicrobial Efficacy of HandHygiene Agents 58Manfred L. Rotter, Syed A. Sattar, and Miranda Suchomel 10. Hand Hygiene Technique 70Marie-Noëlle Chraïti and Andreas F. Widmer 11. Compliance with Hand Hygiene Best Practices 76Benedetta Allegranzi, Andrew J. Stewardson, and Didier Pittet 12. Barriers to Compliance 85John M. Boyce, Benedetta Allegranzi, and Didier Pittet 13. Physicians and Hand Hygiene 89Benedetta Allegranzi, Andrew J. Stewardson, and Didier Pittet 14. Surgical Hand Preparation 94Andreas F. Widmer and Joseph Solomkin 15. Skin Reaction to Hand Hygiene 101Elaine Larson 16. Alcohol-Based Handrub Safety 105John M. Boyce and M. Lindsay Grayson 17. Rinse, Gel, Foam, Soap … Selecting an Agent 109Andreas Voss 18. Behavior and Hand Hygiene 115Mary-Louise McLaws and Hugo Sax 19. Hand Hygiene Promotion Strategies 123Benedetta Allegranzi and Didier Pittet 20. My Five Moments for Hand Hygiene 134Hugo Sax, Benedetta Allegranzi, and Didier Pittet 21. System Change 144Benedetta Allegranzi, Andreas Voss, and Didier Pittet 22. Education of Healthcare Professionals 152Elaine Larson, Marie-Noëlle Chraïti, and Wing-Hong Seto 23. Glove Use and Hand Hygiene 156Marie-Noëlle Chraïti, Benedetta Allegranzi, and Elaine Larson 24. Monitoring Hand Hygiene Performance 162Hugo Sax and John M. Boyce 25. Performance Feedback 172Andrew J. Stewardson and Hugo Sax 26. Marketing Hand Hygiene 180Julie Storr and Hugo Sax 27. Human Factors Design 185Lauren Clack and Hugo Sax 28. Institutional Safety Climate 193Enrique Castro-Sánchez, Alison Holmes, and Didier Pittet 29. Personal Accountability for Hand Hygiene 201Robert M. Wachter and Peter Pronovost 30. Patient Participation and Empowerment 206Yves Longtin, Susan E. Sheridan, and Maryanne McGuckin 31. Religion and Hand Hygiene 216Jaffar A. Al-Tawfiq and Ziad A. Memish 32. Hand Hygiene Promotion from the US Perspective: PuttingWHO and CDC Guidelines into Practice 221Katherine Ellingson 33. WHO Multimodal Promotion Strategy 230Benedetta Allegranzi and Didier Pittet 34. Monitoring Your Institution (Hand Hygiene Self-Assessment Framework) 244Benedetta Allegranzi, Andrew J. Stewardson, and Didier Pittet 35. National Hand Hygiene Campaigns 249Claire Kilpatrick and Julie Storr 36. Hand Hygiene Campaigning: From One Hospital to the Entire Country 256Philip L. Russo and M. Lindsay Grayson 37. Improving Hand Hygiene through Joint Commission Accreditation and the Joint Commission Center for Transforming Healthcare 263Mark R. Chassin, Barbara I. Braun, and Anne Marie Benedicto 38. A Worldwide WHO Hand Hygiene in Healthcare Campaign 275Claire Kilpatrick, Julie Storr, and Benedetta Allegranzi 39. The Economic Impact of Improved Hand Hygiene 285Nicholas Graves 40. Hand Hygiene: Key Principles for the Manager 294Eleanor Murray, Alison Holmes, and Didier Pittet 41. Effect of Hand Hygiene on Infection Rates 299Benedetta Allegranzi, Stephan Harbarth, and Didier Pittet 42A.Hand Hygiene in Specific Patient Populations and Situations: Critically Ill Patients 317Caroline Landelle, Jean-Christophe Lucet, and Didier Pittet 42B. Hand Hygiene in Specific Patient Populations and Situations: Neonates and Pediatrics 324Walter Zingg and Hanan H. Balkhy 42C. Hand Hygiene in Long-Term Care Facilities and Home Care 329Maria Luisa Moro, Marie-Noëlle Chraïti, and Benedetta Allegranzi 42D.Hand Hygiene in Ambulatory Care 337Marie-Noëlle Chraïti, Sepideh Bagheri Nejad, and Benedetta Allegranzi 42E. Hand Hygiene in Hemodialysis 344Marie-Noëlle Chraïti, Sepideh Bagheri Nejad, and Benedetta Allegranzi 42F. Hand Hygiene in Specific Patient Populations and Situations: Anesthesiology 350François Stéphan 43. Hand Hygiene in Resource-Poor Settings 357Nizam Damani, Shaheen Mehtar, and Benedetta Allegranzi 44A. Role of Hand Hygiene in MRSA Control 367Stephan Harbarth 44B. Role of Hand Hygiene in Clostridium difficile Control 373John M. Boyce and Walter Zingg 44C. Role of Hand Hygiene in Respiratory Diseases Including Influenza 378Wing Hong Seto and Benjamin J. Cowling 44D. Handborne Spread of Noroviruses and its Interruption 385Syed A. Sattar and Yves Longtin 45. Conducting a Literature Review on Hand Hygiene 391Daniela Pires, Fernando Bellissimo-Rodrigues, and Didier Pittet Appendix 400 Index 409
£108.86
John Wiley & Sons Inc Introduction to Global Health Promotion
Book SynopsisIntroduction to Global Health Promotion addresses a breadth and depth of public health topics that students and emerging professionals in the field must understand as the world's burden of disease changes with non-communicable diseases on the rise in low- and middle-income countries as their middle class populations grow.Table of ContentsPreface xiii Acknowledgments xix The Editors xxi SOPHE xxv The Contributors xxvii Chapter 1 The State of Global Health 1Richard Skolnik Chapter 2 Global Health Promotion: The State of the Science 31David V. McQueen Chapter 3 Global Health Promotion and the Social Determinants of Health 49Kumanan Rasanathan and Alyssa Sharkey Chapter 4 Models of Health Behavior Change: International Applications 65Rick S. Zimmerman, Zhiwen Xiao, Purnima Mehrotra, and Charles Roy Chapter 5 Two Health Communication Approaches: Communication for Behavioral Impact (COMBI) and Entertainment Education 99Everold N. Hosein, May G. Kennedy, and Sandra de Castro Buffington Chapter 6 Global Health Promotion in the Context of Human Rights 129Elvira Beracochea and Lubna Ahmed Chapter 7 eHealth and Global Health Promotion 145Sheana S. Bull, Gretchen Domek, and Deborah Thomas Chapter 8 Reducing Maternal and Infant Mortality: Meeting a Global Challenge 173Padmini Murthy Chapter 9 Malaria Prevention and Control 191Fouzia Farooq and Elke S. Bergmann-Leitner Chapter 10 Global Immunization Initiatives from a Health Promotion Perspective 209Marilyn E. Rice, Jon K. Andrus, Virginia Swezy, and Rick S. Zimmerman Chapter 11 The Evolving Global HIV Pandemic: Epidemiology, Prevention, and Future Priorities 239Ralph J. DiClemente, Puja Seth, and Purnima Mehrotra Chapter 12 Community-Based Risk Communication in Epidemics and Emerging Disease Settings 271Renata Schiavo, Karen M. Hilyard, and Ewart C. Skinner Chapter 13 Noncommunicable Diseases (NCDs): Moving Toward Health Promotion 303C. James Hospedales, Andr´e Pascal Kengne, Branka Legetic, and Adriana Blanco Marquizo Chapter 14 Women's Cancers 339Silvana Luciani and Irene Agurto Chapter 15 Health Promotion in Families and Communities: An Integrated Approach from Latin America and the Caribbean 363Fernando Zacarias, Adrian Diaz, Manuel Pena, Adela Paez Jimenez, Leticia Martinez, and Gina Tambini Chapter 16 Oral Health Promotion 383Margaret Scarlett and Gary L. Kreps Chapter 17 Adaptation and Implementation of Public Health Innovations in Developing Countries 425Bonita Stanton, Xiaoming Li, and Linda Kaljee Chapter 18 Health Promotion in the Global Setting: The Role of International Organizations and Governments 445John (Jack) Bryant and F. Curtiss Swezy Chapter 19 The Future of Global Health Promotion 467Rick S. Zimmerman, Jon K. Andrus, and C. James Hospedales Author Index 491 Subject Index 499
£76.46
John Wiley & Sons Inc Perspectives on Complex Global Challenges
Book SynopsisExamines current and prospective challenges surrounding global challenges of education, energy, healthcare, security, and resilience This book discusses issues in large-scale systems in the United States and around the world. The authors examine the challenges of education, energy, healthcare, national security, and urban resilience. The book covers challenges in education including America''s use of educational funds, standardized testing, and the use of classroom technology. On the topic of energy, this book examines debates on climate, the current and future developments of the nuclear power industry, the benefits and cost decline of natural gases, and the promise of renewable energy. The authors also discuss national security, focusing on the issues of nuclear weapons, terrorism and cyber security. Urban resilience is addressed in the context of natural threats such as hurricanes and floods. Studies the usage of a globalized benchmark for both studentTable of ContentsContributors xiii Introduction and Overview 1Elisabeth Paté-Cornell, William B. Rouse, and Charles M. Vest Can America Still Compete? 17Norman R. Augustine Section I Education 21 1 Introduction 23 Overview of Contributions 28 References 30 2 K-12 Education Reform in the United States 33Craig R. Barrett Great Teachers 35 High Expectations 36 Tension in the System 36 Intelligent use of Technology in the Classroom 37 Make Education Relevant for the Student 38 3 Secure America’s Economic Future by Investing in Young Children 41Deborah J. Stipek Reference 43 Recommended Readings 43 4 The Future of Teaching in the United States 45Linda Darling-Hammond References 48 5 The Conundrum of Controlling College Costs 49Lawrence S. Bacow References 52 6 Military Education 53William J. Perry Section II Energy 59 7 Introduction 61 Energy Demand 62 The Electric Grid 64 Nuclear Power 65 Renewable Energy 66 Role of Consumers 67 Overview of Contributions 69 References 71 8 The Future of the US Electric Grid 73Richard Schmalensee System Organization 73 Bulk Power 74 Distribution 76 Cybersecurity 78 Concluding Observations 78 9 The Revolution in Natural Gas 81John Deutch 10 The Future of Nuclear Power in the United States 85Richard A. Meserve 11 Renewable Energy: Balancing Risk and Reward 89Richard H. Truly and Michal C. Moore Section III Healthcare 93 12 Introduction 95 Driving Forces 96 Complexity of Decision Making 98 Value and Healthcare Delivery 98 Overview of Contributions 100 References 102 13 How to Move Toward Value-Based Healthcare? 105Denis A. Cortese and Robert K. Smoldt Recommended Readings 107 14 Delivering on the Promise to Reduce the Cost of Healthcare with Electronic Health Records 109William W. Stead Recommended Readings 112 15 Big Data in Health and Healthcare: Hopes and Fears for the Future 113Elizabeth A. McGlynn 16 Medical Education: One Size Does not Fit All 117Lloyd B. Minor and Michael M.E. Johns Section IV Security 121 17 Introduction 123 Emergence of Non-State Powers and Terrorist Groups 123 Resizing the US Nuclear Arsenal 124 Cybersecurity 125 Intelligence 126 Biological Weapons 126 US Defense Budget 127 Overview of Contributions 128 References 132 18 Vigilance in an Evolving Terrorism Landscape 133Michael E. Leiter 19 The Market’s Role in Improving Cybersecurity 139Herbert Lin References 144 20 On Nuclear Weapons 145George P. Shultz 21 The Nuclear Security Challenge: It is International 147Siegfried S. Hecker 22 Nuclear Weapon Reductions Must be Part of Strategic Analysis 151Henry A. Kissinger and Brent Scowcroft 23 Maintaining us Leadership in Science Technology and Innovation for National Security 155Jacques S. Gansler Section V Resilience 159 24 Introduction 161 Framework for Urban Resilience 162 Potential Approaches 163 Overview of Contributions 164 References 167 25 Urban Resilience: How Cities need to Adapt to Unanticipated and Sudden Change 169Michael Batty References 171 26 Buying Down Risks and Investing in Resilience 173Richard Reed References 177 27 Resilience from the Perspective of a Chief Urban Designer 179Alexandros Washburn 28 Engineering for Resilience: Ten Commandments of the Dutch Approach 183Theo Toonen System of Systems 186 Public Expertise 187 Crowded House 188 Co-Governance 188 Clear Direction 189 Executive Leadership 190 International Bat Strategy 191 Implementation Democracy 191 Shared Service 193 Checks and Balances 193 References 194 Conclusions 195 Index 197
£54.86
John Wiley and Sons Ltd Beyond One Health
Book SynopsisTackling One Health from a multi-disciplinary perspective, this book offers in-depth insight into how our health and the health of every living creature and our ecosystem are all inextricably connected. Presents critical population health topics, written by an international group of experts Addresses the technical aspects of the subject Offers potential policy solutions to help mitigate current threats and prevent additional threats from occurring Table of ContentsList of Contributors xiii Foreword by Chadia Wannous and David Nabarro xvii Foreword by Lonnie King xix Preface xxi Section 1 The Science of One Health 1 1 Epidemiology: Science as a Tool to Inform One Health Policy 3Yvette J. Johnson]Walker and John B. Kaneene 1.1 Introduction 3 1.2 Enhancing Our Understanding of Health and Disease 5 1.2.1 Causes of Disease 5 1.2.1.1 Deterministic Models of Disease 6 1.2.1.2 Hill’s Causal Criteria 7 1.2.1.3 Multifactorial Models of Disease Causation 8 1.2.1.4 Breaking the Chain of Transmission 8 1.2.2 Assessing the Impact of Disease 10 1.2.3 Natural Course of Disease 13 1.2.3.1 Reservoirs of Disease 13 1.2.3.2 Humans as a Reservoir 14 1.2.3.3 Domestic Animal Reservoirs 14 1.2.3.4 Wildlife Reservoirs 17 1.2.3.5 Environmental Reservoirs 17 1.3 From Understanding Epidemiology to Public Policy 19 1.3.1 Assessments of Diagnostic Test Reliability 20 1.3.2 Determination of Safety and Effectiveness of New Treatments and Vaccines 20 1.3.3 Assessment of Health at the Level of the Individual, Community, or Ecosystem and Establish Standards of Care for Prevention and Treatment Protocols/Programs 21 1.3.4 Establishing Disease Response Regulations and Control Standards 22 1.4 Examples of the Benefits of Using a One Health Approach 23 1.4.1 Overall Summary of Practical Experiences Applying a One Health Approach 25 References 28 2 Health Impacts in a Changing Climate 31Donald J. Wuebbles 2.1 Introduction 31 2.2 Our Changing Climate 32 2.2.1 Climate Change Effects on Temperature 33 2.2.2 Climate Change Effects on Precipitation 34 2.2.3 Climate Change Effects on Severe Weather 37 2.3 The Basis for a Human Cause for Climate Change 41 2.4 Twenty]first Century Projections of Climate Change 43 2.5 Climate and Health 49 2.5.1 Temperature]Related Death and Illness 49 2.5.2 Air Quality Impacts 50 2.5.3 Vector]Borne Diseases 50 2.5.4 Water]Related Illnesses 52 2.5.5 Food Safety, Nutrition, and Distribution 52 2.5.6 Extreme Weather]Related Impacts 54 2.5.7 Mental Health and Well]being 54 2.5.8 Climate–Health Risk Factors and Populations of Concern 55 2.6 Summary and a Look Forward 55 References 56 3 Food Safety and Security 61Megin Nichols, Lauren Stevenson, Casey Barton Behravesh, and Robert V. Tauxe 3.1 Evolution of Food Production 61 3.2 Foodborne Illness 63 3.3 A One Health Approach to Foodborne Illness Detection and Response 68 3.4 Antibiotic Resistance and Food Safety 75 3.5 Zoonotic Disease and Foodborne Pathogens 78 3.6 Outbreak Response Communication 80 References 83 4 Water Security in a Changing World 89Jeffrey M. Levengood, Ari Hörman, Marja]Liisa Hänninen, and Kevin O’Brien 4.1 Introduction 89 4.2 Waterborne Pathogens and Contaminants : Technologies for Drinking Water Treatment and Management of Water Safety 90 4.2.1 Waterborne Pathogens 90 4.2.2 Antibiotic]Resistant Bacteria in Source and Drinking Water 91 4.2.3 Chemical Hazards in the Drinking Water 93 4.2.4 Pharmaceuticals in Wastewater and Raw Water Sources 93 4.2.5 Water Treatment Methods 93 4.2.5.1 Thermal Treatment 94 4.2.5.2 Chemical Disinfection 94 4.2.5.3 Filtration 95 4.2.5.4 Other Treatment Methods 96 4.2.6 Surveillance for Waterborne Diseases 96 4.2.7 Requirements for Drinking Water Quality 96 4.2.8 Water Safety Plans (WSPs) 97 4.3 The Water/Energy/Food Nexus: Mitigating Global Risks 99 4.3.1 Water/Energy Nexus 99 4.3.1.1 Nuclear 102 4.3.1.2 Coal 103 4.3.1.3 Natural Gas 103 4.3.1.4 Renewables 103 4.3.1.5 Water/Energy Nexus Summary 104 4.3.2 Water/Food Nexus 104 4.3.2.1 Water/Food Nexus Summary 107 4.3.3 Water/Energy/Food Nexus: Summary and Next Steps 107 Acknowledgments 108 References 108 5 One Toxicology, One Health, One Planet 115Daniel Hryhorczuk, Val R. Beasley, Robert H. Poppenga, and Timur Durrani 5.1 Introduction 115 5.1.1 History 115 5.1.2 Toxic Chemicals in Our Environment 117 5.1.3 One Toxicology 118 5.2 Key Concepts 120 5.2.1 Dose]Response Relationships 120 5.2.2 Differences in Susceptibility 120 5.2.3 Periods of Increased Susceptibility 122 5.2.4 Receptors 122 5.2.5 Toxicokinetics and Toxicodynamics 123 5.3 Ecotoxicology and Human Exposures 124 5.3.1 Everyday Toxicology and Ecotoxicology: Contrasts, Complexities, and Challenges 124 5.3.2 Toxicant Fate in the Environment 125 5.3.3 Contrasts in Feasibility: Examinations and Interventions 129 5.3.4 Indirect Effects of Chemicals 132 5.3.5 Direct Immunotoxicity and Indirectly Mediated Immunosuppression 137 5.3.6 Neurotoxicity 138 5.3.7 Endocrine Disruption 138 5.3.8 Reproductive and Developmental Toxicity 140 5.4 Toxicological Risk Assessment and One Health 141 5.4.1 Risk Assessment 141 5.4.2 Regulatory Toxicology 141 5.4.3 One Health and One Toxicology on One Earth 142 5.5 Conclusions 143 References 144 6 Biodiversity and Health 153Dominic A. Travis, Jonathan D. Alpern, Matteo Convertino, Meggan Craft, Thomas R. Gillespie, Shaun Kennedy, Cheryl Robertson, Christopher A. Shaffer, and William Stauffer 6.1 Introduction 153 6.2 Connectivity 155 6.2.1 Biodiversity as an Indicator of Health 155 6.2.2 Social Factors 158 6.3 Grand Challenges, Development Goals, Global Health Security, and Ecosystem Health 159 6.3.1 The Case of Agriculture, Food Security, and Biodiversity 161 6.3.2 The Case of Wildlife Trade, Bushmeat, and Biodiversity 162 6.3.3 The Case of Infectious Diseases and Biodiversity 165 6.3.4 The Case of Climate Change, Conflict, and Human and Animal Migration 166 6.4 Conclusions and a Way Forward 168 6.4.1 The Application of Complexity Science and Technology Tools to Optimize Health and Environmental Outcomes 168 References 170 7 Emerging Infectious Diseases: Old Nemesis, New Challenges 177Ronald C. Hershow and Kenneth E. Nusbaum 7.1 Introduction 177 7.2 Rabies 180 7.2.1 Natural History 180 7.2.2 The Epizoology of Rabies Virus 181 7.2.3 Global Burden 181 7.3 Avian Influenza 182 7.3.1 Natural History 182 7.3.2 Recent Outbreaks 183 7.4 Zika Virus 186 7.5 Ebola Virus Disease (EVD) 188 7.6 Summary 189 Acknowledgments 190 References 190 8 Reigning Cats and Dogs: Perks and Perils of Our Courtship with Companion Animals 195Sandra L. Lefebvre and Robert V. Ellis 8.1 Introduction 195 8.2 Benefits and Hazards of Human]Pet Relationships 197 8.2.1 Physical and Mental Health 197 8.2.1.1 Impacts on Humans 197 8.2.1.2 Impacts on Pets 200 8.2.2 Overweight and Obesity 202 8.2.3 Feeding Practices and Illness 203 8.2.3.1 Human Illness Related to Pet Feeding Practices 203 8.2.3.2 Pet Illness Related to Feeding Practices 205 8.2.4 Infectious Disease Transmission 206 8.2.4.1 Companion Animal]to]Human Transmission 206 8.2.4.2 Human]to]Companion Animal Transmission 216 8.2.5 Pets, People, and Antimicrobial Resistance 216 8.2.6 Social and Community Health 221 8.2.7 Domestic Health and Violence 223 8.3 Interactions Among Humans, Pets, and the Environment 223 8.3.1 Working Dogs 223 8.3.2 Environmental Toxicants 224 8.3.3 Pets and the External Environment 225 8.3.4 Disaster Preparedness 227 8.3.5 Climate Change 228 8.3.6 Zoonotic Disease Surveillance for Both People and Pets 228 8.4 Conclusion 229 Disclaimer 230 References 230 9 Zoological Institutions and One Health 243Thomas P. Meehan and Yvonne Nadler 9.1 Introduction 243 9.2 Zoos, Aquariums, and Field Conservation 243 9.3 Zoos, Aquariums, and the Care of Animals 244 9.4 Social Aspects of Zoos and Aquariums 245 9.5 Zoonotic Disease Challenges: Protecting Visitors, Staff, and Animals 246 9.6 Case Studies in One Health from Zoological Institutions 249 9.6.1 West Nile Virus: A Case Study for the One Health Paradigm 249 9.6.1.1 Emergence of West Nile Virus in North America 249 9.6.1.2 Centers for Disease Control: ArboNET 250 9.6.1.3 A Failure of Early Coordination 251 9.6.1.4 Lessons Learned from the West Nile Virus Outbreak, 1999 252 9.6.1.5 Zoological Institutions as Forerunners to the ‘One Health’ Paradigm 253 9.6.1.6 Zoological Parks as Sentinels for Human Disease 253 9.6.1.7 A Model for Sentinel Surveillance: The Zoological WNV Surveillance Project 254 9.6.1.8 Lessons Learned from the Zoological WNV Surveillance Project 254 9.6.1.9 The Role of Zoological Institutions in Preparing for Pandemics 255 9.6.2 The Emergence of Highly Pathogenic Avian Influenza Virus, 1999 255 9.6.2.1 Consequences of HPAI Detection in a Zoological Institution 256 9.6.2.2 The Association of Zoos and Aquariums Prepares for HPAI 257 9.6.2.3 Lessons Learned from HPAI Surveillance System 258 9.7 Conclusion 259 References 260 Section 2 Four Perspectives on One Health Policy 265 10 One Health Leadership and Policy 267William D. Hueston, Ed G.M. van Klink, and Innocent B. Rwego 10.1 Introduction and Definitions 267 10.2 Grand Challenges in Health (aka “Wicked Problems”) 267 10.3 Implications of Grand Challenges for One Health Leadership 268 10.4 Critical Competencies for One Health Leadership 268 10.5 Policy]Making with One Health in Mind 269 10.6 Integrating One Health Leadership Approaches in Hierarchical Organizations 270 10.7 Demonstrating One Health Leadership and Policy in Action 271 10.8 Case Study 1: National One Health Policy Development in Cameroon and Rwanda 272 10.8.1 Cameroon 272 10.8.2 Rwanda 272 10.9 Case Study 2: The Campaign for Global Elimination of Dog]Mediated Human Rabies 273 10.10 Case Study 3: Antimicrobial Resistance – USA 274 References 276 11 Implementing One Health 277Laura H. Kahn 11.1 Financing One Health Initiatives 277 11.2 Conclusion 279 References 279 12 The Social Cost of Carbon 281William J. Craven 12.1 Introduction 281 12.2 Some Context on Cost]Benefit Analyses 282 12.3 The Social Cost of Carbon (SCC) 282 12.3.1 Looking at Costs 283 12.3.2 Getting the SCC as Good as it Can Get 285 12.4 Current Challenges to Reducing and Mitigating the Effects of Climate Change 287 References 288 13 Complex Problems, Progressive Policy Solutions, and One Health 291John A. Herrmann 13.1 One Health as Prevention 291 13.1.1 Successes 291 13.1.2 Failures 292 13.2 Translating Science: Risk Communication and Science Literacy 293 13.2.1 Communication of Science 294 13.2.2 Liberal Education and the Sciences 295 13.2.3 Community Empowerment and Participatory Democracy 299 13.3 The Economics of One Health 300 13.4 From Here to There 302 References 302 Section 3 Conclusion 305 14 The Long and Winding Road 307John A. Herrmann and Yvette J. Johnson]Walker 14.1 One Health: Many Facets, All Interrelated 307 14.2 One Health Policy Development 310 14.2.1 Policy Basics and Challenges to Enacting One Health]based Policies 310 14.2.2 Microeconomic One Health Dilemmas 311 14.2.3 One Health Research in Emerging Infectious Diseases: Macroeconomic Dilemmas 312 14.2.4 The Long and Winding Road Forward 313 References 321 Index
£91.76
John Wiley & Sons Inc CMOS Integrated Labonachip System for
Book SynopsisA thorough examination of lab-on-a-chip circuit-level operations to improve system performance A rapidly aging population demands rapid, cost-effective, flexible, personalized diagnostics. Existing systems tend to fall short in one or more capacities, making the development of alternatives a priority. CMOS Integrated Lab-on-a-Chip System for Personalized Biomedical Diagnosis provides insight toward the solution, with a comprehensive, multidisciplinary reference to the next wave of personalized medicine technology. A standard complementary metal oxide semiconductor (CMOS) fabrication technology allows mass-production of large-array, miniaturized CMOS-integrated sensors from multi-modal domains with smart on-chip processing capability. This book provides an in-depth examination of the design and mechanics considerations that make this technology a promising platform for microfluidics, micro-electro-mechanical systems, electronics, and electromagnetics. From CMOS fundamentals to endTable of ContentsPreface x 1 Introduction 1 1.1 Personalized Biomedical Diagnosis 1 1.1.1 Personalized Diagnosis 1 1.1.2 Conventional Biomedical Diagnostic Instruments 3 1.1.2.1 Optical Microscope 3 1.1.2.2 Flow Cytometer 4 1.1.2.3 DNA Sequencer 5 1.2 CMOS Sensor-based Lab-on-a-Chip for System Miniaturization 7 1.2.1 CMOS Sensor-based Lab-on-a-Chip 7 1.2.2 CMOS Sensor 8 1.2.2.1 CMOS Process Fundamentals 8 1.2.2.2 CMOS Sensor Technology 10 1.2.2.3 Multimodal CMOS Sensor 13 1.2.3 Microfluidics 14 1.2.3.1 Microfluidic Fundamentals 14 1.2.3.2 Microfluidics Fabrication 16 1.3 Objectives and Organization of this Book 20 1.3.1 Objectives 20 1.3.2 Organization 20 References 21 2 CMOS Sensor Design 25 2.1 Top Architecture 25 2.2 Noise Overview 25 2.2.1 Thermal Noise 26 2.2.2 Flicker Noise 27 2.2.3 Shot Noise 28 2.2.4 MOSFET Noise Model 29 2.3 Pixel Readout Circuit 29 2.3.1 Source Follower 30 2.3.2 Sub-threshold Gm Integrator 33 2.3.3 CTIA 35 2.4 Column Amplifier 38 2.5 Column ADC 39 2.5.1 Single-Slope ADC 39 2.5.2 Sigma-Delta ADC 43 2.6 Correlated Sampling 49 2.6.1 Correlated Double Sampling 49 2.6.2 Correlated Multiple Sampling 51 2.7 Timing Control 52 2.7.1 Row Timing Control 52 2.7.2 Column Timing Control 55 2.8 LVDS Interface 57 References 59 3 CMOS Impedance Sensor 60 3.1 Introduction 60 3.2 CMOS Impedance Pixel 61 3.3 Readout Circuit 63 3.4 A 96 × 96 Electronic Impedance Sensing System 65 3.4.1 Top Architecture 65 3.4.2 System Implementation 67 3.4.2.1 System Setup 67 3.4.2.2 Sample Preparation 68 3.4.3 Results 68 3.4.3.1 Data Fitting for Single Cell Impedance Measurement 69 3.4.3.2 Cell and Electrode Impedance Analysis 71 3.4.3.3 EIS for Single-Cell Impedance Enumeration 71 References 74 4 CMOS Terahertz Sensor 76 4.1 Introduction 76 4.2 CMOS THz Pixel 76 4.2.1 Differential TL-SRR Resonator Design 76 4.2.1.1 Stacked SRR Layout 76 4.2.1.2 Comparison with Single-ended TL-SRR Resonator 80 4.2.1.3 Comparison with Standing-Wave Resonator 82 4.2.2 Differential TL-CSRR Resonator Design 83 4.3 Readout Circuit 84 4.3.1 Super-regenerative Amplification 84 4.3.1.1 Equivalent Circuit of SRA 84 4.3.1.2 Frequency Response of SRA 86 4.3.1.3 Sensitivity of SRA 86 4.3.2 Super-regenerative Receivers 87 4.3.2.1 Quench-controlled Oscillation 87 4.3.2.2 SRX Design by TL-CSRR 89 4.3.2.3 SRX Design by TL-SRR 91 4.4 A 135 GHz Imager 94 4.4.1 135 GHz DTL-SRR-based Receiver 94 4.4.2 System Implementation 95 4.4.3 Results 95 4.5 Plasmonic Sensor for Circulating Tumor Cell Detection 98 4.5.1 Introduction of CTC Detection 98 4.5.2 SRR-based Oscillator for CTC Detection 99 4.5.3 Sensitivity of SRR-based Oscillator 101 References 103 5 CMOS Ultrasound Sensor 106 5.1 Introduction 106 5.2 CMUT Pixel 107 5.3 Readout Circuit 109 5.4 A 320 × 320 CMUT-based Ultrasound Imaging System 110 5.4.1 Top Architecture 110 5.4.2 System Implementation 111 5.4.2.1 Process Selection 111 5.4.2.2 High Voltage Pulser 112 5.4.2.3 Low-Noise Preamplifier and High Voltage Switch 115 5.4.3 Results 116 5.4.3.1 Simulation Results 116 5.4.3.2 Two-channel AFE IC Measurement Results 117 5.4.3.3 Acoustic Transmission Testing with AFE IC and CMUT 121 5.4.3.4 Acoustic Pulse-echo Testing with AFE IC and CMUT 122 References 124 6 CMOS 3-D-Integrated MEMS Sensor 126 6.1 Introduction 126 6.2 MEMS Sensor 127 6.3 Readout Circuit 127 6.4 A 3-D TSV-less Accelerometer 129 6.4.1 CMOS-on-MEMS Stacking 129 6.4.2 Bonding Reliability 132 6.4.2.1 Al–Au Thermo-compression Shear Strength 132 6.4.2.2 Al–Au Thermo-compression Hermeticity 134 6.4.3 Results 135 6.4.3.1 Standalone Validation of the Readout Circuit 135 6.4.3.2 Functionality Testing of CMOS-on-MEMS Chip 136 6.4.3.3 Reliability Testing of CMOS-on-MEMS Chip 138 References 141 7 CMOS Image Sensor 142 7.1 Introduction 142 7.2 CMOS Image Pixel 145 7.2.1 Structure 145 7.2.1.1 FSI 4 T Pixel 145 7.2.1.2 Back Side Illumination Pixel 147 7.2.1.3 Stack Pixel 148 7.2.2 Noise and Model 150 7.2.2.1 Photon Shot Noise 151 7.2.2.2 Reset Noise 152 7.2.2.3 Thermal Noise 152 7.2.2.4 Flicker Noise 154 7.2.2.5 Fixed Pattern Noise 154 7.3 Readout Circuit 155 7.3.1 Global Serial Readout 156 7.3.2 Correlated Double Sampling 156 7.4 A 3.2 Mega CMOS Image Sensor 158 7.4.1 4-way Shared Pixel Unit 158 7.4.2 Top Architecture 159 7.4.3 System Implementation 162 7.4.4 Results 164 7.4.4.1 System Characterization 164 7.4.4.2 Digital CDS for FPN Reduction 164 7.4.4.3 Blood Cell Imaging Experiments 165 References 167 8 CMOS Dual-mode pH-Image Sensor 169 8.1 Introduction 169 8.2 CMOS Dual-mode pH-Image Pixel 170 8.3 Readout Circuit 172 8.3.1 CDS for Optical Sensing 174 8.3.2 CDS for Chemical Sensing 174 8.4 A 64 × 64 Dual-mode pH-Image Sensor 175 8.4.1 Top Architecture 175 8.4.2 System Implementation 177 8.4.3 Results 177 References 184 9 CMOS Dual-mode Energy-harvesting-image Sensor 186 9.1 Introduction 186 9.2 CMOS EHI Pixel 187 9.3 Readout Circuit 191 9.4 A 96 × 96 EHI Sensing System 195 9.4.1 Top Architecture 195 9.4.2 System Implementation 197 9.4.3 Results 203 References 211 10 DNA Sequencing 213 10.1 Introduction 213 10.2 CMOS ISFET-based Sequencing 213 10.2.1 Overview 213 10.2.2 ISFET-based Sequencing Procedure 215 10.3 CMOS THz-based Genotyping 220 10.3.1 Overview 220 10.3.2 THz-based Genotyping Procedure 220 10.4 Beyond CMOS Nanopore Sequencing 221 10.4.1 Overview 221 10.4.2 Nanopore-based Sequencing Procedure 223 10.5 Summary 227 References 230 11 Cell Counting 231 11.1 Introduction 231 11.2 Optofluidic Imaging System 231 11.2.1 Contact Imaging 231 11.2.2 Optofluidic Imaging System Model 232 11.2.2.1 Resolution Model 232 11.2.2.2 Dynamic Range Model 233 11.2.2.3 Implication to SR Processing 234 11.3 Super-resolution Image Processing 234 11.3.1 Multi-frame SR Processing 235 11.3.2 Single-frame SR Processing 236 11.4 Machine-learning-based Single-frame Super-resolution 237 11.4.1 ELMSR 238 11.4.2 CNNSR 242 11.5 Microfluidic Cytometer for Cell Counting 245 11.5.1 Microfluidic Cytometer System 245 11.5.1.1 System Overview 245 11.5.1.2 Microfluidic Channel Fabrication 246 11.5.1.3 Microbead and Cell Sample Preparation 246 11.5.1.4 Microfluidic Cytometer Design 247 11.5.1.5 Cell Detection 248 11.5.1.6 Cell Recognition 249 11.5.1.7 Cell Counting 250 11.5.2 Results 250 11.5.2.1 Counting Performance Characterization 250 11.5.2.2 Off-Line SR Training 251 11.5.2.3 On-line SR Testing 253 11.5.2.4 On-line Cell Recognition and Counting 254 References 255 12 Conclusion 258 12.1 Summaries 258 12.2 Future Works 260 Index 262
£98.96
John Wiley and Sons Ltd The Complete Dentist
Book SynopsisThe Complete Dentist: Positive Leadership and Communication Skills for Success is a one-of-a-kind guide to starting and running an effective and successful dental practice. Presents tried-and-true ideas and methods for effective communication, blending positive psychology with leadership in dentistry Describes the five elements of success and happiness, offering pathways to a flourishing dental practice Considers the reasons why communication and leadership skills are important for dentists Table of Contents Prologue viii Introduction xiii Part I The Problem 1 1 The Many Faces of Dentistry – A Fragmented Field 3 What is Dentistry? 3 Wholism vs. Reductionism 4 Fragmented Dental Education 7 The Why of Work 10 References and Notes 15 2 Not the Golden Age of Dentistry 16 The Paradox of Duty and Desire 23 References and Notes 27 3 Dentistry Today 29 The Four Stages of Learning 31 Technology – Wagging the Dog 36 Human Interaction Rules 39 References and Notes 41 4 The Ultimate Losers In the End 43 Dentists and Stress 46 Dental Health Today 50 References and Notes 53 Part II The Solution 55 5 The Fundamental Value of Leadership 57 That Vision Thing 62 Climbing The Right Wall 65 My Pledge to You 66 Creating Your Vision Statement 70 References and Notes 70 6 Positive Psychology and Leadership 72 The Well]Being Theory 76 Positive Emotions 77 Engagement 85 Positive Relationships 88 Meaning 93 Accomplishments 100 Conclusion 104 References and Notes 105 7 Passion is the By]product of Mastery – A New Curriculum 109 Passion – The Fire of Desire 109 Passion is the Opposite of Apathy and the By]Product of Mastery 112 What is the Mastery Process? More Evidence of Control 113 References and Notes 117 8 A New Beginning – A New Curriculum 118 References and Notes 126 Part III Leadership Ethos 129 9 What Adam Smith Knew 135 References and Notes 140 10 The Foundation of Ethos – Self]Awareness and Ownership 141 References and Notes 147 11 The Virtues of Emotional Intelligence 148 Self]awareness 151 Self]regulation 151 Self]motivation 153 References and Notes 155 12 Grit, Optimism and Resilience 156 References and Notes 164 13 The TAO of Dentistry and a Culture of Trust 165 References and Notes 173 Part IV Pathos – Other People Matter 175 14 Your Focus – Your Success 179 References and Notes 185 15 The Charismatic Dental Leader 186 16 Contact – The First Four Minutes 193 References and Notes 197 17 Conversation With An Elephant 199 Reference 203 Part V Logos – Where the Rubber Meets the Road 205 18 The Practical Wisdom of Systems and Processes 209 References and Notes 215 19 The Key Systems and Skills 216 References and Notes 222 20 Manage Your Energy, Not Your Time 223 References and Notes 231 21 Master of the Intangibles – It Takes a Team 232 References and Notes 239 Part VI Epilogue 241 A Master in the Art of Living 241 Index
£45.86
John Wiley and Sons Ltd Introduction to One Health
Book SynopsisIntroduction to One Health: An Interdisciplinary Approach to Planetary Health offers an accessible, readable introduction to the burgeoning field of One Health. Provides a thorough introduction to the who, what, where, when, why, and how of One Health Presents an overview of the One Health movement viewed through the perspective of different disciplines Encompasses disease ecology, conservation, and veterinary and human medicine Includes interviews from persons across disciplines important for the success of One Health Includes case studies in each chapter to demonstrate real-world applications Table of ContentsForeword xiii Acknowledgments xv About the Companion Website xvii Part I An Introduction and Impetus for One Health 1 1 Why One Health? 3 1.1 Book Overview 8 1.2 Conclusions and Welcome to One Health 10 End of Chapter Questions & Activities 11 Interview 12 Works Cited 13 2 Our Interconnected World 15 2.1 One Health Challenges on a Connected Planet 17 2.2 Global Challenges for One Health Practitioners 19 2.2.1 Emerging Infectious Diseases and Invasive Species 19 2.2.2 Loss of Biodiversity and Natural Resources 19 2.2.3 Climate Change 21 2.2.4 Environmental Degradation and Environmental Contaminants 21 2.2.5 Loss of Habitat and Increased Interactions of Domestic Animals–Wildlife–Humans 22 2.3 Drivers of Our Connected Health Challenges 22 2.4 Solutions Using a One Health Approach 24 2.5 Connectivity Across the Human–Animal–Environment Interface 25 End of Chapter Questions & Activities 26 Interview 26 Case Study28 Works Cited 29 3 Greatest Threats to Planetary Health 31 3.1 The Climate Crisis 31 3.2 Emerging and Re‐emerging Infectious Diseases 36 3.3 The Loss of Biodiversity 39 3.3.1 Habitat Loss 40 3.3.2 Pollution 41 3.3.3 Invasive Species 44 3.4 The Anthropocene and Inequality 46 3.4.1 Wealth and Income Inequality 46 3.4.2 Global Food Insecurity 48 3.4.3 Environmental Racism 49 3.5 Science Denial 51 3.6 Conclusion 52 End of Chapter Questions & Activities 53 Interview 54 Works Cited 56 Part II The One Health Triad 59 4 Environmental Health as One Health 61 4.1 Threats to Environmental Health 63 4.2 Pollution and Environmental Contamination 64 4.3 Habitat Loss and Land Use Alterations 68 4.4 Environmental Health and Health of the Future 70 4.5 Two Things Exacerbate Everything 71 4.5.1 Population Growth and Consumption 71 4.5.2 Climate Change 72 4.6 Things Can Get Better 72 4.7 Conclusion 74 End of Chapter Questions & Activities 74 Interview 75 Case Study 77 Works Cited 79 5 Animal Health as One Health 81 5.1 Vulture Declines and One Health 83 5.2 Animals that Share Our Planet 85 5.3 How Do We Keep All Animals Healthy on a Changing Planet? 86 5.4 Threats to Animal Health on a Changing Planet 88 5.5 Conclusions 88 End of Chapter Questions & Activities 89 Interview 90 Case Study 91 Works Cited 93 6 Human Health as One Health 95 6.1 Human Health as One Health 96 6.2 Human Disease in the Context of One Health 98 6.2.1 Infectious Diseases 98 6.2.2 Disruption of Embryonic and Fetal Development 99 6.2.3 Diseases of Nourishment 100 6.2.4 Respiratory Disease 102 6.2.5 Cancer 104 6.3 Climate Change and Human Health 105 6.4 Going Forward 105 End of Chapter Questions & Activities 107 Interview 107 Case Study 109 Works Cited 110 Part III Practitioners and Their Tools 113 7 The One Health Practitioner 115 7.1 Who Is a One Health Practitioner? 117 7.2 The Beauty of an Interdisciplinary, Team‐Based Approach 119 7.2.1 Problem Solving 119 7.2.2 One Health Is Anticipatory 120 7.3 Occupational Opportunities in One Health 120 7.3.1 The One Health Triad 120 7.3.2 One Health Practitioners and Their Tools 121 7.3.3 How to Start a Movement 122 7.3.4 The Humanity of Science 122 7.4 The Citizen Practitioner 123 End of Chapter Questions & Activities 124 Interview 124 Case Study 126 Works Cited 127 8 Essential Tools for One Health Practitioners 129 8.1 Why We Need One Health Tools 131 8.2 The Tools of One Health 132 8.2.1 The Tangible: Hard Tools of One Health 132 8.2.2 People Power: The Intangible Tools of One Health 134 8.2.3 Disease Risk Analyses: Linking the Tangible with the Intangible Tools of One Health 138 8.3 Tools to Help Start a One Health Movement 140 8.4 Conclusions 141 End of Chapter Questions & Activities 141 Interview 142 Case Study 144 Works Cited 145 Part IV How to Start a Movement 147 9 Education and Critical Thinking in One Health 149 9.1 Higher Education and One Health 151 9.2 One Health Practitioners as Educators 153 9.3 Conclusions 158 End of Chapter Questions & Activities 158 Interview 159 Case Study 160 Works Cited 161 10 Communication and Advocacy in One Health 163 10.1 A Hole in the Ozone 163 10.2 Scientific Communication 165 10.3 Science Denial and the Cautionary Language of Scientists 166 10.4 Communication as the Bridge‐Building Tool of One Health 168 10.5 Communication as Outreach 168 10.6 Citizen Science as One Health 171 10.7 Communication and Advocacy as a One Health Tool 172 10.8 Conclusion 174 End of Chapter Questions & Activities 174 Interview 175 Case Study 177 Works Cited 179 Part V The Humanities of One Health 181 11 Culture and Theology in One Health 183 11.1 Culture 185 11.2 Culture, Social Structure, and One Health 185 11.2.1 Poverty 185 11.2.2 Marginalization 186 11.2.3 Women and Gender Equity 186 11.3 Culture and Animal/Ecosystem One Health 187 11.4 Religion and One Health 189 11.5 Cultural and Religious Awareness and One Health 191 End of Chapter Questions & Activities 191 Interview 192 Case Study 193 Works Cited 194 12 Economics and One Health 197 12.1 Economics: The Connection Between Values and Behaviors 199 12.2 Cost and Externalities 200 12.3 The Cost and Value of Life 201 12.4 The Conundrum of Economics and the Environment 204 12.5 Business and Sustainability: Patagonia 205 12.6 Business and Sustainability: New Belgium Brewing 205 12.7 Global Economics and Planetary Health 206 End of Chapter Questions & Activities 207 Interview 208 Case Study 210 Works Cited 211 13 Politics and Policy of One Health 213 13.1 What Do We Mean by the Politics of One Health? 215 13.2 How a Health Issue May Become a Political Issue 216 13.3 Political Differences, Realities, and Challenges 217 13.4 Key Local, National, and International One Health Organizations and Movements 218 13.5 Environmental/Biodiversity 218 13.5.1 International Climate Accord 218 13.5.2 International Union for the Conservation of Nature 218 13.5.3 The Convention on International Trade in Endangered Species of Wild Fauna and Flora 219 13.5.4 United States Environmental Protection Agency 219 13.6 Animal and Human Health 219 13.6.1 World Health Organization 219 13.6.2 Food and Agriculture Organization of the United Nations 220 13.6.3 The World Organization for Animal Health 220 13.6.4 Centers for Disease Control and Prevention 220 13.7 Approaching Health Policies Through the One Health Lens 221 13.8 Call to Action – Advocacy, Policy, and Politics 221 13.9 Conclusions 223 End of Chapter Questions & Activities 223 Interview 224 Case Study 226 Works Cited 227 Part VI Where Do We Go From Here? 229 14 Working in a Global Environment 231 14.1 Think Globally, Act Locally, and the Butterfly Effect 232 14.2 How a Global Environment Fits in One Health 233 14.3 Education and Skills Needed to Work and Thrive in a Global World 235 14.4 How To Be a One Health Practitioner in a Global Environment 238 14.5 International Programs, Policies, and Laws for One Health in the Global Environment 239 14.6 Conclusion 240 End of Chapter Questions & Activities 242 Interview 243 Case Study 245 Works Cited 245 15 The Past and Future of One Health 247 15.1 The Lesson of Easter Island 248 15.2 One Health in History 249 15.3 How One Health Became One Health 249 15.4 Our Futures 250 15.5 Our Current Actions Establish the Path 252 15.6 The Ethics of Our Decisions 252 15.7 Conclusions 252 End of Chapter Questions & Activities 252 Interview 253 Works Cited 255 Glossary 257 Index 267
£93.56
John Wiley and Sons Ltd Genetic Counseling Practice
Book SynopsisThe second edition of Genetic Counseling Practice: Advanced Concepts and Skills, provides in-depth content regarding the advanced competencies for meeting patient needs across the changing landscape of genetic counseling practice. The content aligns with the Reciprocal Engagement Model (REM) of practice which integrates the biomedical knowledge and psychosocial aspects of genetic counseling. This edition has been revised and expanded to reflect advances made in the present-day field. Edited by a team two genetic counselors and a psychologist, the chapters offer a holistic picture of genetic counseling. Chapter authors are all recognized experts in the profession. The chapters are grounded in evidence-based practice and research. Each chapter includes learning activities to help readers apply concepts and skills. Featured topic areas include: Meeting the needs of culturally diverse patients Addressing challenging patient dynamics Working wTable of ContentsPreface x About the Authors xi Acknowledgments xvii 1 Introduction 1Bonnie S. LeRoy, Patricia McCarthy Veach, and Nancy P. Callanan Development of the 2nd Edition 2 References 7 2 Complicated Shadows: The Limitations of Autonomy in Genetic Counseling Practice 9Robert G. Resta Objectives 9 Definition and Focus 10 Seven Limitations of Autonomy 11 Summary 18 Learning Activities 19 References 21 3 Actively Engaging with Patients in Decision-Making 25Andrea Shugar and Cheryl Shuman Objectives 25 A Brief History of the Medical Encounter: From Paternalism to Shared Decision-Making 25 Psychological Aspects of Decision-Making 26 Informed Decision-Making 30 Summary 41 Learning Activities 41 Acknowledgment 48 References 48 4 Risk Assessment and Communication: A Complex Process 53Shannan Delany Dixon, MaryAnn W. Campion, and Claire N. Singletary Objectives 53 Introduction 53 Risk Assessment in Genetic Counseling 54 Risk Communication 61 Influences on Risk Perception 65 Summary 70 Learning Activities 70 References 73 5 A Genetic Counselor’s Guide to Understanding Grief 79Nadia Ali and Cecelia Bellcross Objectives 79 Introduction 80 The Grief Process 82 Types of Grief 89 Conclusion 101 Learning Activities 102 References 105 6 Patient Anger: Insights and Strategies 109Lynn Schema Objectives 109 Introduction 109 Challenges Posed by Patient Anger 116 Practice Applications 118 Conclusion 123 Summary Points 123 Learning Activities 124 References 127 7 Resistance and Adherence: Understanding the Patient’s Perspective 131Krista Redlinger-Grosse Objectives 131 Definition and Concepts 132 Resistance 133 Adherence and Non-adherence 140 Summary 144 Learning Activities 145 References 148 8 Countertransference: Making the Unconscious Conscious 153Krista Redlinger-Grosse Objectives 153 Definitions and Concepts 154 The Countertransference Process 155 Manifestations and Effects of Countertransference 161 Management of Countertransference 166 Summary 169 Learning Activities 169 References 171 9 Supporting Family Communication About Genetic Conditions 177Marion Mcallister, Rhona Macleod, and Alison Metcalfe Objectives 177 Introduction 177 Literature Review 178 Application of Select Family Systems Theory Interventions Adapted to Genetic Counseling 180 Summary 186 Learning Activities 187 Acknowledgments 188 References 188 10 Developmentally Based Approaches for Counseling Children and Adolescents 191Stephanie Austin and Kelly Schoch Objectives 191 Introduction 191 Child and Adolescent Development 192 Theoretical Framework 195 Chronic Illness and Children 197 Strategies for Genetic Counseling with Children and Adolescents 199 Conclusion 212 Summary Points 212 Learning Activities 212 References 214 11 Cultural Competency and Genetic Counseling: Key Concepts 219Nancy Steinberg Warren Objectives 219 Introduction 219 Definitions and Key Concepts 220 Health Disparities 226 Conceptualizing Cultural Competence 230 Developing Cultural Competency 231 Summary 236 Learning Activities 236 Resources for Cultural Knowledge, Cases, Teaching, and Learning Exercises 239 References 240 12 Cultural Competency: Application to Genetic Counseling 247Nancy Steinberg Warren Objectives 247 Introduction 247 Cultural Competency and the Genetic Counseling Process 248 Explanatory Models of Health and Well-being 253 Health Literacy 259 Working with Interpreters and Translators 260 Summary 263 Learning Activities 264 Resources for Cultural Knowledge, Cases, Teaching, and Learning Exercises 265 References 266 13 Education in Genetic Counseling: The Impacts of Genetic Literacy and Adult Learning 271Andrea L. Durst and Rachel Mills Objectives 271 Introduction 271 General Literacy in the United States 273 Health Literacy 274 Genetic Literacy 276 Genetic Literacy Considerations for Genetic Counselors 280 Adult Education Theory in Practice 294 Summary Points 301 Learning Activities 302 References 304 14 Adapting Genetic Counseling Practice to Different Models of Service Delivery 317Angela Trepanier and Dawn C. Allain Objectives 317 Introduction 317 Defining Service Delivery Models 318 Attributes of Alternative Service Delivery Models 319 Putting it all Together – Practice Implications 329 Conclusions 333 Learning Activities 333 References 335 15 “Oh The Places You’ll Go!” The Genetic Counselor Professional Development Journey 341Catherine A. Reiser Objectives 341 Introduction 341 Literature Review 343 Reflective Practice 347 Optimizing Self-Reflection 352 Leadership 354 Summary Points 356 Acknowledgments 356 Learning Activities 357 References 360 16 Development of the Genetic Counseling Profession: A Professionalization Process 365Bonnie Jeanne Baty Objectives 365 What Makes a Field of Practice a Profession? 365 How Does Genetic Counseling Measure Up to the Characteristics of a Profession? 366 Milestones in the Development of the Genetic Counseling Profession 366 Genetic Counseling and the General Model of Professionalization 369 Looking to the Future: Milestones that Need Further Development to Advance the Professionalization of Genetic Counseling 370 How is Professionalization of Genetic Counseling Relevant to Genetic Counseling Practitioners? 375 Summary 376 Learning Activities 377 References 378 Index 383
£88.16
John Wiley & Sons Inc The Law of TaxExempt Healthcare Organizations
Book SynopsisGet up to date on 2019 healthcare law and newly relevant issues The Law of Tax-Exempt Healthcare Organizations 2019 Supplement provides complete and comprehensive practitioner updates and analysis in a single volume. Tackling complex legal issues with plain-English explanations and the appropriate citations, this guide is a must-have resource for organizations and their advisors. The companion website provides extensive appendices for further reference, as well as helpful downloadable tables that facilitate a more efficient approach to practice. Healthcare law is a complex field, and keeping up with the frequent changes to federal law is itself a full time job. This book eliminates the need for extended research time by collecting all of the newest and relevant guidelines into one place. Get up to date on the latest IRS forms, guidance, and procedures Interpret complex legal issues correctly and appropriately Reference relevTable of ContentsPreface ix About the Authors xi Book Citations xv 1 Tax-Exempt Healthcare Organizations: An Overview 1 1.2 Defining Tax-Exempt Organizations 1 1.5 Charitable Healthcare Organizations 1 1.8 Promotion of Health 2 1.10 ABLE Programs 2 3 Public Charities and Private Foundations (New) 5 3.3 Commerciality Doctrine 5 4 Private Inurement, Private Benefit, and Excess Benefit Transactions 9 4.4 Private Inurement—Scope and Types 9 4.6 Essence of Private Benefit 10 4.9 Excess Benefit Transactions 12 5 Public Charities and Private Foundations 13 5.1 Public Institutions 13 5.6 Recognition of Change in Public Charity Status 13 7 Lobbying and Political Activities 15 7.1 Legislative Activities Limitation 15 7.4 Political Activities Limitation 16 7.5 Business Expense Deduction Rules and Political Activities 18 7.7 Public Policy Advocacy Activities 19 7.8 Political Activities of Social Welfare Organizations 19 8 Hospitals 21 8.3 Public Hospitals 21 9 Managed Care Organizations 23 9.3 Commercial-Type Insurance Providers 23 9.5 Recent Developments 23 13 Other Provider and Supplier Organizations 27 13.3 Qualified Nonprofit Health Insurance Issuers 27 13.5 Accountable Care Organizations 28 16 For-Profit Subsidiaries 33 16.3 Attribution of Subsidiary’s Activities to Exempt Parent 33 17 Exempt and Nonexempt Cooperatives 35 17.1 Cooperative Hospital Service Organizations 35 18 Business Leagues 37 18.1 Business Leagues in General 37 18.2 Healthcare Trade Associations 38 19 Other Health-Related Organizations 39 19.4 Hospital Management Services Organizations 39 19.5 Regional Health Information Organizations 40 20 Healthcare Provider Reorganizations 41 20.1 Some Basics about Reorganizations 41 21 Mergers and Conversions 43 21.4 Conversion from Nonexempt to Exempt Status 43 22 Partnerships and Joint Ventures (New) 45 22.9 Whole-Hospital Joint Ventures 45 24 Tax Treatment of Unrelated Business Activities 47 24.2 Definition of Trade or Business 47 24.3 Definition of Regularly Carried On 49 24.5 Application of Substantially Related Test to Healthcare Organizations 50 24.11 Pharmacy, Medical Supplies, and Service Sales 51 24.12 Laboratory Testing Services 51 24.13 Medical Research 52 24.18 Other Exceptions to Unrelated Income Taxation 53 24.20 Revenue from Controlled Organizations 55 24.21 Unrelated Debt-Financed Income 55 24.23 Computation of Unrelated Business Taxable Income 55 25 Physician Recruitment and Retention 61 25.5 Specific Recruitment and Retention Techniques 61 26 Charity Care 63 26.6 Definitional and Reporting Issues 63 26.9 Charity Care and National Health Reform 64 26.10 Additional Statutory Requirements for Hospitals 64 26.12 Provider Taxes (New) 82 27 Worker Classification and Employment Taxes 85 27.7 Medical Residents and the Student Exception 85 28 Compensation and Employee Benefits 87 28.3 Executive Compensation 87 28.5 Overview of Employee Benefits Law 87 28.6 Deferred Compensation in General 88 28.7 Excessive Executive Compensation (New) 91 30 Tax-Exempt Bond Financing 95 30.3 Disqualification of Tax-Exempt Bonds 95 31 Fundraising Regulation 105 31.2 Federal Law Regulation 105 33 Governance 107 33.4A IRS Ruling Policy 107 34 Exemption and Public Charity Recognition Processes 111 34.1 Exemption Recognition Process 111 34.5 Public Charity Status 121 34.6 Group Exemption 121 34.7A Notice Requirements for Social Welfare Organizations (New) 122 34.8 Procedure Where Determination Is Adverse 123 34.9 Constitutional Law Aspects of Process 125 35 Maintenance of Tax-Exempt Status and Avoidance of Penalties 127 35.1 Material Changes 127 35.2A Modification of Tax Exemption (New) 129 35.4 Redesigned Annual Information Return 129 35.5 Disclosure Requirements 130 35.6 IRS Disclosure to State Officials 131 36 IRS Audits of Healthcare Organizations 133 36.2 Audit Procedures 133 Cumulative Table of Cases 139 Cumulative Table of IRS Revenue Rulings 149 Cumulative Table of IRS Revenue Procedures 153 Cumulative Table of IRS Private Letter Rulings 155 Cumulative Table of IRS Technical Advice Memoranda 161 Table of Chief Counsel Advice Memoranda 163 Cumulative Table of IRS General Counsel Memoranda 165 Table of Tax Reform Legislation 167 Cumulative Index 173
£157.50
John Wiley and Sons Ltd Kelly Vanas Nursing Leadership and Management
Book SynopsisNursing Leadership & Management, Fourth Editionprovides a comprehensive look at the knowledge and skills required to lead and manage at every level of nursing, emphasizing the crucial role nurses play in patient safety and the delivery of quality health care. Presented in three units, readers are introduced to a conceptual framework that highlights nursing leadership and management responsibilities for patient-centered care delivery to the patient, to the community, to the agency, and to the self. This valuable new edition: Includes new and up-to-date information from national and state health care and nursing organizations, as well as new chapters on the historical context of nursing leadership and management and the organization of patient care in high reliability health care organizationsExplores each of the six Quality and Safety in Nursing (QSEN) competencies: Patient-Centered Care, Teamwork and Collaboration, Evidence-based Practice (EBP), Quality Improvement (QI), Safety, and InformaticsProvides review questions for all chapters to help students prepare for course exams and NCLEX state board examsFeatures contributions from experts in the field, with perspectives from bedside nurses, faculty, directors of nursing, nursing historians, physicians, lawyers, psychologists and more Nursing Leadership & Management, Fourth Editionprovides a strong foundation for evidence-based, high-quality health care for undergraduate nursing students, working nurses, managers, educators, and clinical specialists.Table of ContentsContributors xxi former contributors to the third edition xxxi Preface xxxix Foreword xlvii How to use this book xlix About the editors li Acknowledgments lv About the Companion Website lvii Unit 1: Kelly's Nursing Leadership and Management 1 1 Kelly's Nursing Leadership, Management, and Motivation 1 2 The Health Care Environment 29 3 Nursing Leadership and Management in a Historical Context 66 4 Organization of Patient Care in High Reliability Care Organizations 86 5 Organization and Staffing of Patient Care at the Unit Level 120 6 Health Care Economics 157 7 Hospital Department and Unit Budgets 184 Unit 2: Leadership and Management of Patient-Centered Care 206 8 Patient-Centered Care 206 9 Patient and Health Care Education 230 10 Patient Outcomes and Evidence-Based Health Care 261 11 Searching for the Evidence 280 12 Quality Improvement of Patient Care 303 13 Improving Quality at the Bedside 328 14 Safety: Patient and Health Care Team 348 15 Nursing Informatics 374 Unit 3: Nursing and the Interprofessional Team 411 16 Interprofessional Teamwork and Collaboration 411 17 Members of the Interprofessional Team 441 18 Delegation, Assignment, and Supervision of Patient Care 456 19 Time Management and Setting Patient Care Priorities 490 20 Change, Clinical Decision Making and Innovation 511 21 Power and Politics 535 22 Legal Aspects of Nursing 566 23 Ethical Aspects of Nursing 587 24 Culture, Generational Differences, and Spirituality 605 Unit 4: Leadership and Management of Self and the Future 640 25 NCLEX-RN Preparation 640 26 Entry into the Profession: Your First Job 668 27 Career Planning and Professional Development 695 28 Balancing a Healthy Personal and Professional Life 722 29 Nursing Career Opportunities 734 Appendix 1 754 Appendix 2 770 Appendix 3 772 Appendix 4 774 Appendix 5 776 Appendix 6 778 Glossary 780 Index 791
£95.90
John Wiley & Sons Inc OntologyBased Information Retrieval for
Book SynopsisWith the advancements of semantic web, ontology has become the crucial mechanism for representing concepts in various domains. For research and dispersal of customized healthcare services, a major challenge is to efficiently retrieve and analyze individual patient data from a large volume of heterogeneous data over a long time span. This requirement demands effective ontology-based information retrieval approaches for clinical information systems so that the pertinent information can be mined from large amount of distributed data. This unique and groundbreaking book highlights the key advances in ontology-based information retrieval techniques being applied in the healthcare domain and covers the following areas: Semantic data integration in e-health care systems Keyword-based medical information retrieval Ontology-based query retrieval support for e-health implementation Ontologies as a database management system technology for medicalTable of ContentsPreface xix Acknowledgment xxiii 1 Role of Ontology in Health Care 1Sonia Singla 1.1 Introduction 2 1.2 Ontology in Diabetes 3 1.2.1 Ontology Process 4 1.2.2 Impediments of the Present Investigation 5 1.3 Role of Ontology in Cardiovascular Diseases 6 1.4 Role of Ontology in Parkinson Diseases 8 1.4.1 The Spread of Disease With Age and Onset of Disease 10 1.4.2 Cost of PD for Health Care, Household 11 1.4.3 Treatment and Medicines 11 1.5 Role of Ontology in Depression 13 1.6 Conclusion 15 1.7 Future Scope 15 References 15 2 A Study on Basal Ganglia Circuit and Its Relation With Movement Disorders 19Dinesh Bhatia 2.1 Introduction 19 2.2 Anatomy and Functioning of Basal Ganglia 21 2.2.1 The Striatum-Major Entrance to Basal Ganglia Circuitry 22 2.2.2 Direct and Indirect Striatofugal Projections 23 2.2.3 The STN: Another Entrance to Basal Ganglia Circuitry 25 2.3 Movement Disorders 26 2.3.1 Parkinson Disease 26 2.3.2 Dyskinetic Disorder 27 2.3.3 Dystonia 28 2.4 Effect of Basal Ganglia Dysfunctioning on Movement Disorders 29 2.5 Conclusion and Future Scope 31 References 31 3 Extraction of Significant Association Rules Using Pre- and Post-Mining Techniques—An Analysis 37M. Nandhini and S. N. Sivanandam 3.1 Introduction 38 3.2 Background 39 3.2.1 Interestingness Measures 39 3.2.2 Pre-Mining Techniques 40 3.2.2.1 Candidate Set Reduction Schemes 40 3.2.2.2 Optimal Threshold Computation Schemes 41 3.2.2.3 Weight-Based Mining Schemes 42 3.2.3 Post-Mining Techniques 42 3.2.3.1 Rule Pruning Schemes 43 3.2.3.2 Schemes Using Knowledge Base 43 3.3 Methodology 44 3.3.1 Data Preprocessing 44 3.3.2 Pre-Mining 46 3.3.2.1 Pre-Mining Technique 1: Optimal Support and Confidence Threshold Value Computation Using PSO 46 3.3.2.2 Pre-Mining Technique 2: Attribute Weight Computation Using IG Measure 48 3.3.3 Association Rule Generation 50 3.3.3.1 ARM Preliminaries 50 3.3.3.2 WARM Preliminaries 52 3.3.4 Post-Mining 56 3.3.4.1 Filters 56 3.3.4.2 Operators 58 3.3.4.3 Rule Schemas 58 3.4 Experiments and Results 59 3.4.1 Parameter Settings for PSO-Based Pre-Mining Technique 60 3.4.2 Parameter Settings for PAW-Based Pre-Mining Technique 60 3.5 Conclusions 63 References 65 4 Ontology in Medicine as a Database Management System 69Shobowale K. O. 4.1 Introduction 70 4.1.1 Ontology Engineering and Development Methodology 72 4.2 Literature Review on Medical Data Processing 72 4.3 Information on Medical Ontology 75 4.3.1 Types of Medical Ontology 75 4.3.2 Knowledge Representation 76 4.3.3 Methodology of Developing Medical Ontology 76 4.3.4 Medical Ontology Standards 77 4.4 Ontologies as a Knowledge-Based System 78 4.4.1 Domain Ontology in Medicine 79 4.4.2 Brief Introduction of Some Medical Standards 81 4.4.2.1 Medical Subject Headings (MeSH) 81 4.4.2.2 Medical Dictionary for Regulatory Activities (MedDRA) 81 4.4.2.3 Medical Entities Dictionary (MED) 81 4.4.3 Reusing Medical Ontology 82 4.4.4 Ontology Evaluation 85 4.5 Conclusion 86 4.6 Future Scope 86 References 87 5 Using IoT and Semantic Web Technologies for Healthcare and Medical Sector 91Nikita Malik and Sanjay Kumar Malik 5.1 Introduction 92 5.1.1 Significance of Healthcare and Medical Sector and Its Digitization 92 5.1.2 e-Health and m-Health 92 5.1.3 Internet of Things and Its Use 94 5.1.4 Semantic Web and Its Technologies 96 5.2 Use of IoT in Healthcare and Medical Domain 98 5.2.1 Scope of IoT in Healthcare and Medical Sector 98 5.2.2 Benefits of IoT in Healthcare and Medical Systems 100 5.2.3 IoT Healthcare Challenges and Open Issues 100 5.3 Role of SWTs in Healthcare Services 101 5.3.1 Scope and Benefits of Incorporating Semantics in Healthcare 101 5.3.2 Ontologies and Datasets for Healthcare and Medical Domain 103 5.3.3 Challenges in the Use of SWTs in Healthcare Sector 104 5.4 Incorporating IoT and/or SWTs in Healthcare and Medical Sector 106 5.4.1 Proposed Architecture or Framework or Model 106 5.4.2 Access Mechanisms or Approaches 108 5.4.3 Applications or Systems 109 5.5 Healthcare Data Analytics Using Data Mining and Machine Learning 110 5.6 Conclusion 112 5.7 Future Work 113 References 113 6 An Ontological Model, Design, and Implementation of CSPF for Healthcare 117Pooja Mohan 6.1 Introduction 117 6.2 Related Work 119 6.3 Mathematical Representation of CSPF Model 122 6.3.1 Basic Sets of CSPF Model 123 6.3.2 Conditional Contextual Security and Privacy Constraints 123 6.3.3 CSPF Model States CsetofStates 124 6.3.4 Permission Cpermission 124 6.3.5 Security Evaluation Function (SEFcontexts) 124 6.3.6 Secure State 125 6.3.7 CSPF Model Operations 125 6.3.7.1 Administrative Operations 125 6.3.7.2 Users’ Operations 127 6.4 Ontological Model 127 6.4.1 Development of Class Hierarchy 127 6.4.1.1 Object Properties of Sensor Class 129 6.4.1.2 Data Properties 129 6.4.1.3 The Individuals 129 6.5 The Design of Context-Aware Security and Privacy Model for Wireless Sensor Network 129 6.6 Implementation 133 6.7 Analysis and Results 135 6.7.1 Inference Time/Latency/Query Response Time vs. No. of Policies 135 6.7.2 Average Inference Time vs. Contexts 136 6.8 Conclusion and Future Scope 137 References 138 7 Ontology-Based Query Retrieval Support for E-Health Implementation 143Aatif Ahmad Khan and Sanjay Kumar Malik 7.1 Introduction 143 7.1.1 Health Care Record Management 144 7.1.1.1 Electronic Health Record 144 7.1.1.2 Electronic Medical Record 145 7.1.1.3 Picture Archiving and Communication System 145 7.1.1.4 Pharmacy Systems 145 7.1.2 Information Retrieval 145 7.1.3 Ontology 146 7.2 Ontology-Based Query Retrieval Support 146 7.3 E-Health 150 7.3.1 Objectives and Scope 150 7.3.2 Benefits of E-Health 151 7.3.3 E-Health Implementation 151 7.4 Ontology-Driven Information Retrieval for E-Health 154 7.4.1 Ontology for E-Heath Implementation 155 7.4.2 Frameworks for Information Retrieval Using Ontology for E-Health 157 7.4.3 Applications of Ontology-Driven Information Retrieval in Health Care 158 7.4.4 Benefits and Limitations 160 7.5 Discussion 160 7.6 Conclusion 164 References 164 8 Ontology-Based Case Retrieval in an E-Mental Health Intelligent Information System 167Georgia Kaoura, Konstantinos Kovas and Basilis Boutsinas 8.1 Introduction 167 8.2 Literature Survey 170 8.3 Problem Identified 173 8.4 Proposed Solution 174 8.4.1 The PAVEFS Ontology 174 8.4.2 Knowledge Base 179 8.4.3 Reasoning 180 8.4.4 User Interaction 182 8.5 Pros and Cons of Solution 183 8.5.1 Evaluation Methodology and Results 183 8.5.2 Evaluation Methodology 185 8.5.2.1 Evaluation Tools 186 8.5.2.2 Results 187 8.6 Conclusions 189 8.7 Future Scope 190 References 190 9 Ontology Engineering Applications in Medical Domain 193Mariam Gawich and Marco Alfonse 9.1 Introduction 193 9.2 Ontology Activities 195 9.2.1 Ontology Learning 195 9.2.2 Ontology Matching 195 9.2.3 Ontology Merging (Unification) 195 9.2.4 Ontology Validation 196 9.2.5 Ontology Verification 196 9.2.6 Ontology Alignment 196 9.2.7 Ontology Annotation 196 9.2.8 Ontology Evaluation 196 9.2.9 Ontology Evolution 196 9.3 Ontology Development Methodologies 197 9.3.1 TOVE 197 9.3.2 Methontology 198 9.3.3 Brusa et al. Methodology 198 9.3.4 UPON Methodology 199 9.3.5 Uschold and King Methodology 200 9.4 Ontology Languages 203 9.4.1 RDF-RDF Schema 203 9.4.2 OWL 205 9.4.3 OWL 2 205 9.5 Ontology Tools 208 9.5.1 Apollo 208 9.5.2 NeON 209 9.5.3 Protégé 210 9.6 Ontology Engineering Applications in Medical Domain 212 9.6.1 Ontology-Based Decision Support System (DSS) 213 9.6.1.1 OntoDiabetic 213 9.6.1.2 Ontology-Based CDSS for Diabetes Diagnosis 214 9.6.1.3 Ontology-Based Medical DSS within E-Care Telemonitoring Platform 215 9.6.2 Medical Ontology in the Dynamic Healthcare Environment 216 9.6.3 Knowledge Management Systems 217 9.6.3.1 Ontology-Based System for Cancer Diseases 217 9.6.3.2 Personalized Care System for Chronic Patients at Home 218 9.7 Ontology Engineering Applications in Other Domains 219 9.7.1 Ontology Engineering Applications in E-Commerce 219 9.7.1.1 Automated Approach to Product Taxonomy Mapping in E-Commerce 219 9.7.1.2 LexOnt Matching Approach 221 9.7.2 Ontology Engineering Applications in Social Media Domain 222 9.7.2.1 Emotive Ontology Approach 222 9.7.2.2 Ontology-Based Approach for Social Media Analysis 224 9.7.2.3 Methodological Framework for Semantic Comparison of Emotional Values 225 References 226 10 Ontologies on Biomedical Informatics 233Marco Alfonse and Mariam Gawich 10.1 Introduction 233 10.2 Defining Ontology 234 10.3 Biomedical Ontologies and Ontology-Based Systems 235 10.3.1 MetaMap 235 10.3.2 GALEN 236 10.3.3 NIH-CDE 236 10.3.4 LOINC 237 10.3.5 Current Procedural Terminology (CPT) 238 10.3.6 Medline Plus Connect 238 10.3.7 Gene Ontology 239 10.3.8 UMLS 240 10.3.9 SNOMED-CT 240 10.3.10 OBO Foundry 240 10.3.11 Textpresso 240 10.3.12 National Cancer Institute Thesaurus 241 References 241 11 Machine Learning Techniques Best for Large Data Prediction: A Case Study of Breast Cancer Categorical Data: k-Nearest Neighbors 245Yagyanath Rimal 11.1 Introduction 246 11.2 R Programming 250 11.3 Conclusion 255 References 255 12 Need of Ontology-Based Systems in Healthcare System 257Tshepiso Larona Mokgetse 12.1 Introduction 258 12.2 What is Ontology? 259 12.3 Need for Ontology in Healthcare Systems 260 12.3.1 Primary Healthcare 262 12.3.1.1 Semantic Web System 262 12.3.2 Emergency Services 263 12.3.2.1 Service-Oriented Architecture 263 12.3.2.2 IOT Ontology 264 12.3.3 Public Healthcare 265 12.3.3.1 IOT Data Model 265 12.3.4 Chronic Disease Healthcare 266 12.3.4.1 Clinical Reminder System 266 12.3.4.2 Chronic Care Model 267 12.3.5 Specialized Healthcare 268 12.3.5.1 E-Health Record System 268 12.3.5.2 Maternal and Child Health 269 12.3.6 Cardiovascular System 270 12.3.6.1 Distributed Healthcare System 270 12.3.6.2 Records Management System 270 12.3.7 Stroke Rehabilitation 271 12.3.7.1 Patient Information System 271 12.3.7.2 Toronto Virtual System 271 12.4 Conclusion 272 References 272 13 Exploration of Information Retrieval Approaches With Focus on Medical Information Retrieval 275Mamata Rath and Jyotir Moy Chatterjee 13.1 Introduction 276 13.1.1 Machine Learning-Based Medical Information System 278 13.1.2 Cognitive Information Retrieval 278 13.2 Review of Literature 279 13.3 Cognitive Methods of IR 281 13.4 Cognitive and Interactive IR Systems 286 13.5 Conclusion 288 References 289 14 Ontology as a Tool to Enable Health Internet of Things Viable 5G Communication Networks 293Nidhi Sharma and R. K. Aggarwal 14.1 Introduction 293 14.2 From Concept Representations to Medical Ontologies 295 14.2.1 Current Medical Research Trends 296 14.2.2 Ontology as a Paradigm Shift in Health Informatics 296 14.3 Primer Literature Review 297 14.3.1 Remote Health Monitoring 298 14.3.2 Collecting and Understanding Medical Data 298 14.3.3 Patient Monitoring 298 14.3.4 Tele-Health 299 14.3.5 Advanced Human Services Records Frameworks 299 14.3.6 Applied Autonomy and Healthcare Mechanization 300 14.3.7 IoT Powers the Preventive Healthcare 301 14.3.8 Hospital Statistics Control System (HSCS) 301 14.3.9 End-to-End Accessibility and Moderateness 301 14.3.10 Information Mixing and Assessment 302 14.3.11 Following and Alerts 302 14.3.12 Remote Remedial Assistance 302 14.4 Establishments of Health IoT 303 14.4.1 Technological Challenges 304 14.4.2 Probable Solutions 306 14.4.3 Bit-by-Bit Action Statements 307 14.5 Incubation of IoT in Health Industry 307 14.5.1 Hearables 308 14.5.2 Ingestible Sensors 308 14.5.3 Moodables 308 14.5.4 PC Vision Innovation 308 14.5.5 Social Insurance Outlining 308 14.6 Concluding Remarks 309 References 309 15 Tools and Techniques for Streaming Data: An Overview 313K. Saranya, S. Chellammal and Pethuru Raj Chelliah 15.1 Introduction 314 15.2 Traditional Techniques 315 15.2.1 Random Sampling 315 15.2.2 Histograms 316 15.2.3 Sliding Window 316 15.2.4 Sketches 317 15.2.4.1 Bloom Filters 317 15.2.4.2 Count-Min Sketch 317 15.3 Data Mining Techniques 317 15.3.1 Clustering 318 15.3.1.1 STREAM 318 15.3.1.2 BRICH 318 15.3.1.3 CLUSTREAM 319 15.3.2 Classification 319 15.3.2.1 Naïve Bayesian 319 15.3.2.2 Hoeffding 320 15.3.2.3 Very Fast Decision Tree 320 15.3.2.4 Concept Adaptive Very Fast Decision Tree 320 15.4 Big Data Platforms 320 15.4.1 Apache Storm 321 15.4.2 Apache Spark 321 15.4.2.1 Apache Spark Core 321 15.4.2.2 Spark SQL 322 15.4.2.3 Machine Learning Library 322 15.4.2.4 Streaming Data API 322 15.4.2.5 GraphX 323 15.4.3 Apache Flume 323 15.4.4 Apache Kafka 323 15.4.5 Apache Flink 326 15.5 Conclusion 327 References 328 16 An Ontology-Based IR for Health Care 331J. P. Patra, Gurudatta Verma and Sumitra Samal 16.1 Introduction 331 16.2 General Definition of Information Retrieval Model 333 16.3 Information Retrieval Model Based on Ontology 334 16.4 Literature Survey 336 16.5 Methodolgy for IR 339 References 344
£164.66
John Wiley and Sons Ltd Nanotechnology in Medicine
Book SynopsisTable of ContentsPreface xiii List of Contributors xv List of Abbreviations xix Part I Nanomedicine: Nanotoxicological Insights 1 1 Nanomedicines: Applications and Toxicological Concerns 3 Mrunali Patel, Rashmin Patel, and Mahendra Rai 1.1 Introduction 3 1.2 Nanomedicine’s Revolution 9 1.3 Potential Applications of Nanomedicine 10 1.3.1 Diagnosis 10 1.3.2 Drug Delivery 12 1.3.3 Tissue Engineering and Regenerative Medicine 17 1.4 Clinical Translation of Nanomedicine 18 1.5 Nanotoxicological Challenges 19 1.6 Safety Issues and Regulations 22 1.7 Conclusion and Future Perspectives 23 References 24 2 Microbial Biopolymers and Their Derivatives as Nanotechnological Tools for Medicine: Applications, Advantages, Toxicity, and Safety 29 Paulo Ricardo Franco Marcelino, Fernanda Gonçalves, Nayelen Sayuri Aizawa, Henrique Paiva Pereira, Talita Martins Lacerda, and Silvio Silvério da Silva 2.1 Introduction 29 2.2 Natural Polymers: Conceptualization, Classifications, and Physicochemical Characteristics 30 2.3 Applications of Biopolymers in Nanoparticles, Nanofibers, and Drug Delivery Systems of Therapeutic Importance 35 2.4 Safety of Microbial Biopolymers Used in Nanoscale-Systems for Therapeutic Applications 38 2.5 Conclusions 40 References 41 Part II Nanoparticles: Toxicity and Safety 47 3 Selenium Nanoparticles: Toxicity and Safety 49 Irina A. Shurygina, Irina S. Trukhan, Nataliya N. Dremina, and Michael G. Shurygin 3.1 Introduction 49 3.2 Selenium Forms 50 3.3 Toxicity of Selenium Nanoparticles 52 3.4 Toxicity Mechanisms 56 3.5 Conclusion 60 References 60 4 Impact of Nanoparticles on Protozoa 67 Daniela Plachá and Josef Jampílek 4.1 Introduction 67 4.1.1 Antiprotozoal Drugs 72 4.2 Nanosystems 74 4.2.1 Preparation and Synthesis of Nanoparticles and Systems 75 4.3 Nanosystems with Effect on Human Parasitic Protozoa 77 4.3.1 Malaria 77 4.3.2 Trypanosomiases 79 4.3.3 Leishmaniasis 81 4.3.4 Toxoplasmosis 87 4.3.5 Cryptosporidium 89 4.3.6 Acanthamoeba 90 4.4 Nanosystems with Effect on Veterinary Parasitic Protozoa 91 4.5 Nanomaterial Toxicity on Beneficial Protozoa 93 4.6 Conclusion 96 Acknowledgment 97 References 97 5 Toxicity of Metallic Nanoparticles: A Pressing Issue 109 Tejal Mehta, Dhaivat Parikh, Kartik Hariharan, Namdev Dhas, and Viral Patel 5.1 Introduction 109 5.2 Toxicity of Metal Nanoparticles and Influence of Physicochemical Properties 110 5.2.1 Toxicity of Copper and Copper Oxide Nanoparticles 110 5.2.2 Toxicity of Gold Nanoparticles 112 5.2.2.1 Physicochemical Factors Influencing AuNPs’ Toxicity 112 5.2.3 Toxicity of Silver Nanoparticles 115 5.2.4 Toxicity of Zinc Oxide Nanoparticles 117 5.2.5 Toxicity of Iron Oxide Nanoparticles 118 5.2.6 Physicochemical Properties Affecting Toxicity 119 5.3 Accumulation and Toxicity of Metal-Based Nanoparticles in Various Organs 119 5.4 Conclusion and Future Perspectives 128 Acknowledgment 128 References 128 6 Toxicity, Safety, and Biodistribution of Multifunctional Mesoporous Silica Nanoparticles 137 Mansi Athalye, Rashmin Patel, and Mrunali Patel 6.1 Introduction 137 6.2 Bioapplicability of Mesoporous Silica Nanoparticles 138 6.3 Biodistribution, Toxicity, and Safety of MSN 139 6.3.1 Factors Affecting Biodistribution of Mesoporous Silica Nanoparticles 140 6.3.1.1 Particle Size 140 6.3.1.2 Particle Shape 142 6.3.1.3 Functionalization 142 6.3.1.4 Dose 144 6.3.1.5 Route of Administration 145 6.4 Safety Evaluation of Mesoporous Silica Nanoparticles 145 6.4.1 Cytotoxicity 146 6.4.2 Tissue Compatibility 147 6.4.3 Genotoxicity 147 6.4.4 Immunotoxicity 148 6.4.5 Autophagy 148 6.4.6 Endothelial Dysfunction and Toxic Effects on Blood Cells 149 6.4.7 Blood Compatibility 149 6.4.8 Neurotoxicity 149 6.5 Conclusion and Future Directions 149 References 153 7 Safety and Toxicity Issues of Polymeric Nanoparticles: A Serious Concern 156 Priya Patel, Naimish Vyas, and Mihir Raval 7.1 Introduction 156 7.2 Application of Nanomaterials 157 7.3 Classification of Nanoparticles (NPs) 157 7.3.1 Polymeric Nanoparticles 158 7.3.1.1 Advantages of Polymeric Nanoparticles 159 7.3.1.2 Polymers Used in the Preparation of Polymeric Nanoparticles 159 7.3.1.3 Methods of Preparation of Polymeric Nanoparticles 160 7.3.1.4 Polymeric Nanoparticles in Drug Delivery 162 7.4 Nanotoxicology 163 7.4.1 Toxicity of Nanoparticles 163 7.4.2 Tissue Toxicity of Nanomedicine 164 7.4.3 Mechanisms of Nanoparticle Toxicity 164 7.4.4 Toxicity of Polymeric Nanoparticles 164 7.4.5 Nanoformulations Showing Toxicity 165 7.5 Safety Assessment of Nanomedicines by Methodological Considerations 167 7.5.1 Nanoparticles Safety Study 168 7.5.2 Methodological Considerations for Safety Assessment of Nanomedicines 169 7.6 Conclusion and Future Perspectives 170 References 170 8 Green Synthesis of Copper and Copper-Based Nanoparticles for Their Use in Medicine: Toxicity and Safety 174 Sadhucharan Mallick and Piyali Sabui 8.1 Introduction 174 8.2 Green Synthesis Methods of Copper and Copper-Based Nanoparticles 176 8.2.1 Fungi-Assisted Synthesis of Nanoparticles 176 8.2.2 Actinomycetes-Assisted Synthesis of Nanoparticles 176 8.2.3 Bacteria-Assisted Synthesis of Nanoparticles 177 8.2.4 Algae-Assisted Synthesis of Nanoparticles 177 8.2.5 Phytochemical-Assisted Synthesis of Nanoparticles 177 8.2.6 Biomolecule and Biopolymer-Mediated Synthesis of Nanoparticles 178 8.3 Purification of Copper and Copper-Based Nanoparticles 179 8.4 Characterization of Green Synthesized Copper and Copper-Based Nanoparticles 179 8.5 Copper and Copper-Based Nanoparticles as Nanomedicines 179 8.5.1 Application as Antibacterial Agents 179 8.5.2 Application as Antifungal Agents 182 8.5.3 Application as Antiviral Agents 182 8.5.4 Application as a Targeted Drug Delivery System 182 8.5.5 Application as Anticancer Agents 183 8.5.6 Applications in Molecular Imaging 184 8.6 Copper and Copper-Based Nanoparticles and Their Toxicity 184 8.6.1 Nanotoxicology 184 8.6.2 Different Types of Toxicity 185 8.6.3 Toxicity Effect of Copper and Copper-Based Nanoparticles 185 8.7 Safety Implications of Copper and Copper-Based Nanoparticles 186 8.8 Future Perspectives 187 8.9 Conclusion 188 References 189 Part III Nanotoxicology and Drug Delivery 195 9 Gene Delivery Using Nanocarriers: Toxicity and Safety Aspects 197 Imran Vhora and Nirav Khatri 9.1 Introduction 197 9.2 Nanocarrier Types 198 9.2.1 Lipid-Based Nanocarriers 198 9.2.2 Polymeric Nanocarriers 200 9.3 Target Diseases and Routes of Administration 200 9.4 Learnings from Clinical Trials 214 9.4.1 Toxicity with Systemic Delivery – Intravenous Administration 215 9.4.2 Toxicity with Local Delivery 215 9.4.2.1 Pulmonary Delivery 216 9.4.2.2 Intratumoral and Other Local Delivery in Cancer 216 9.4.2.3 Subcutaneous, Intradermal, and Intramuscular Delivery 216 9.5 Mechanisms of Toxicity of Gene Delivery Nanocarriers 217 9.5.1 Cellular Damage and Inflammatory Mediators 217 9.5.2 ROS Induction 219 9.5.2.1 Off-target Effects of the Genetic Cargo 219 9.6 Overcoming Toxicity Issues with Nanocarrier-Mediated Gene Therapy 220 9.6.1 Modification of Genetic Cargoes 220 9.6.2 Modification of Nanocarrier System 220 9.6.2.1 Optimizing Excipient Chemistry – Lipid and Polymer Chemistry 220 9.6.2.2 Modification of Nanocarrier Morphology 222 9.6.3 Preclinical Testing for Expected Toxicities 223 9.7 Future Perspectives and Conclusion 225 References 226 10 Toxicity and Safety Evaluation of Lipid-Based Nanoparticles for Brain Delivery 233 Mitali Patel and Priyanshi Patel 10.1 Introduction 233 10.2 Barriers Across Brain Delivery 234 10.2.1 The Blood–Brain Barrier (BBB) 234 10.2.2 The Blood Cerebrospinal Fluid (BCSF) Barrier 234 10.3 Role of Lipid Nanoparticles in Brain Delivery 235 10.3.1 Liposomes 236 10.3.2 Solid Lipid Nanoparticles (SLNs) 236 10.3.3 Nanostructured Lipid Carriers (NLCs) 237 10.3.4 Lipid–Drug Conjugates (LDCs) 237 10.3.5 Lipid Polymer Hybrid Nanoparticles (LPHNPs) 238 10.4 Transport Mechanisms Involved for Brain Delivery 238 10.4.1 Paracellular Transport 238 10.4.2 Transcellular Transport 238 10.4.3 Carrier-mediated Transport 238 10.4.4 Receptor-mediated Endocytosis 238 10.4.5 Adsorptive-mediated Endocytosis 239 10.5 Toxicity of Lipid Nanoparticles 239 10.6 Safety of Lipid Nanoparticles 240 10.7 Conclusion and Future Perspectives 242 References 242 11 Risk Assessment of Injectable Nanoparticles Used as Nanomedicine 248 Marco Vinícius Chaud, Fernando Batain, Eliana Barbosa Souto, Patrícia Severino, Aleksandra Zielińska, and Thais Francine Ribeiro Alves 11.1 Introduction 248 11.2 Nanomaterials, Nanoparticles, and Nanoformulation 249 11.3 Injectable Nanoparticles Toxicity 251 11.4 Safety of Nanoparticles in Acute and Chronic Studies 253 11.5 Future Perspectives and Conclusion 254 References 255 12 Dermatological Delivery of Nanodrugs: Applications, Toxicity, and Safety 259 Saurabh Shivalkar, Arushi Verma, Vishal Singh, and Amaresh Kumar Sahoo 12.1 Introduction 259 12.2 An Overview of Dermatology and Nanodrugs 260 12.3 Nanomaterials for Dermatologically Active Nanodrugs 262 12.4 Nanoformulations for Topical and Transdermal Delivery 265 12.5 Applications of Dermatological Nanodrugs and Its Delivery Mechanisms 268 12.5.1 Prevention 268 12.5.1.1 Antisepsis 268 12.5.1.2 Cosmetics and Photoprotection 269 12.5.2 Diagnosis 269 12.5.3 Therapeutic Applications 270 12.5.3.1 Phototherapy 270 12.5.3.2 Sebaceous Gland Disorders 270 12.5.3.3 Treatment of Inflammatory Skin Diseases 270 12.5.3.4 Other Therapeutic Applications 270 12.6 Toxicity Evaluation of Dermatologically Active Nanodrugs 271 12.6.1 Nanodrugs and Toxicity Due to Penetration 271 12.6.2 Genotoxicity 273 12.7 Safety Considerations 273 12.8 Limitations and Risk 274 12.9 Conclusion 274 References 275 13 Nanonutraceuticals: Considerations for Toxicity and Safety Assessment 281 Shah Esha Bhavin and Anuradha Ketan Gajjar 13.1 Introduction 281 13.2 Novel Carrier-Based Drug Delivery Systems 282 13.2.1 Lipidic Nanosystems 283 13.2.1.1 Non-Vesicular Systems 283 13.2.1.2 Vesicular Systems 283 13.2.2 Polymeric Nanosystems 283 13.2.3 Lipid Polymer Nanosystems 285 13.3 Safety and Toxicity Assessment of Nanoparticles 285 13.4 Approaches for Biodegradable Nanoparticles 289 13.5 Modified Nanocarriers (Nanosponges) 291 13.5.1 Cyclodextrin-Based Nanosponges 291 13.6 Conclusion and Future Perspectives 293 References 293 14 Current Challenges and Future Needs for Nanotoxicity and Nanosafety Assessment 299 Ravish J. Patel, Amit Alexander, Anu Puri, and Bappaditya Chatterjee 14.1 Introduction 299 14.2 Nanomaterials: Risk Assessment 302 14.3 The Hurdles in Toxicity Evaluation of Nanomaterials 304 14.3.1 Physicochemical Properties of Nanomaterials’ Characterization 304 14.3.1.1 Size of Nanomaterials 304 14.3.1.2 Composition Effects 304 14.3.1.3 Surface-Related Effects 304 Agglomeration 305 14.3.1.5 Solubility 305 14.3.1.6 Surface Charge and Dispersity 305 14.3.1.7 Dose Metric 305 14.3.2 In vitro, In vivo, and In silico Approaches for the Assessment of Toxicity for the Nanomaterials 305 14.4 Nanosafety Assessment Tools 307 14.5 Conclusion and Perspectives 308 References 310 Part IV Nanotechnology, Ethics, and Regulatory Framework 315 15 Safety Regulations for the Use of Nanotechnological Products for Biomedical Applications: A Systematic Literature Review 317 Raquel Von Hohendorff, Wilson Engelmann, and Daniele Weber S. Leal 15.1 Introduction 317 15.2 The State-of-the-art of Biomedical Applications of Nano-Products 318 15.3 The Scientific Perspective on Nano-products for Biomedical Applications, Risks, and Regulations 322 15.4 Using RRI as a Methodological Pathway Toward Communication Between the Science System and the Law System 324 15.5 Final Considerations and New Propositions 340 Notes 341 References 342 16 Nanoethics and Nanotechnology 349 Iti Chauhan, Madhu Verma, and Mohd Yasir 16.1 Introduction 349 16.1.1 Types of Nanotechnology 349 16.1.2 Applications of Nanotechnology 349 16.2 Nanoethics 351 16.2.1 Regulatory Agencies 354 16.2.1.1 Nanotechnology and State Regulation (India) 355 16.2.2 Distributive Justice 356 16.2.2.1 Bridging the Gap 357 16.2.3 Nanoweapons 358 16.2.4 Ethics in Nanomedicine 358 16.2.4.1 Ethics in Research and Development 359 16.2.4.2 Health and Safety Issues 360 16.2.4.3 Toxicity Associated with Nanoparticulate System 361 16.2.5 Privacy and Confidentiality 361 16.2.6 Human Enhancement 362 16.2.7 Nanopollution 363 16.2.7.1 Health Issues 363 16.2.7.2 Measuring Nanomaterials’ Concentration in the Environment 364 16.2.7.3 Environmental Issues 365 16.2.7.4 Social Issues 365 16.2.7.5 Speculative Issue 366 16.2.8 Educational Issues 367 16.2.9 Biological Issues 367 16.3 Conclusion 368 References 368 17 Current Regulatory Framework in Nanotechnology and Medicine 373 Nitin Dubey and Nidhi Dubey 17.1 Introduction 373 17.1.1 Classification of Nanomaterials 374 17.1.2 Nanoparticles 374 17.2 Quality Attributes and Regulatory Concerns of Nanomaterials 375 17.2.1 Physicochemical Characterization 375 17.2.2 Nonclinical Studies for Nanomaterials 376 17.2.3 Clinical Studies for Nanomaterials 377 17.2.4 Identification of Hazardous Material 377 17.2.5 Exposure Risk to Humans and Environment During Nanomaterial Manufacturing, Storage, or Disposal 378 17.3 Quality Assessment of Nanomedicines 380 17.4 Current Regulatory Framework over Nanomaterials 381 17.4.1 USA 382 17.4.1.1 ANSI 387 17.4.1.2 ASTM 387 17.4.2 European Union 387 17.4.2.1 CEN 390 17.4.3 Taiwan 390 17.4.4 Iran 390 17.4.5 Canada 390 17.4.6 Australia 391 17.4.7 Japan 392 17.4.8 India 392 17.4.9 People’s Republic of China 393 17.4.10 Republic of Korea 394 17.4.11 Russia 394 17.4.12 WHO 394 17.4.13 OECD 394 17.4.14 ISO 396 17.4.15 VAMAS 397 17.5 Conclusion and Future Outlook 401 References 402 Index 407
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John Wiley & Sons Inc Health Economics and Financing
Book SynopsisThe latest edition of the gold standard in the economics and financing of health care In the newly revised Sixth Edition of Health Economics and Financing, an expert team of authors delivers an authoritative discussion of key topics in the economic and finance issues relevant to health care. From cost-benefit and cost-effectiveness analyses to the economic considerations driving the choices of physicians, hospitals, and pharmaceutical companies, the book explores the influence of financial considerations both public and private that remain front-of-mind for modern health care decision makers.Table of ContentsPreface xix Acknowledgments xxiii About the Authors xxv Foreword xxvii 1 Choices: Money, Medicine, and Health 1 2 Demand and Supply 20 3 Cost-Benefit and Cost-Effectiveness Analysis 40 4 Financing Medical Care: Health Insurance Contracts: Managed Care 63 5 Physicians 98 6 Medical Education, Organization, and Business Practices 116 7 Hospitals 136 8 Management and Regulation of Hospital Costs 151 9 Long-Term Care 170 10 Pharmaceuticals 188 11 Financing and Ownership of Health Care Providers 207 12 History, Demography, and the Growth of Modern Medicine 229 13 Macroeconomics of Medical Care 254 14 The Role of Government and Public Goods 279 15 International Comparisons of Health and Health Expenditures 308 16 Value for Money in the Future of Health Care 325 Glossary G-1 Index I-1
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