Gastrointestinal and colorectal surgery Books

Book SynopsisAcute appendicitis is one of the most common surgical abdominal emergencies worldwide, with a lifetime risk of 8.6% for males and 6.7% for females. This compilation discusses how while non-operative treatment of appendicitis has been proposed as an alternative to surgery, appendicectomy remains the mainstay of treatment in most cases and techniques have shifted from open to laparoscopic methods. The current knowledge in pathogenesis, diagnosis, and clinical management of acute appendicitis is also discussed. Next, the authors present an updated review chapter of appendicitis regarding its prevalence and risk factors, particularly how the diagnosis of appendicitis is based on a history of diffuse abdominal pain, which usually starts in the central region of the abdomen and migrates to the lower right quadrant of the abdomen. The residual remnant or "stump" of the appendix after an initial appendectomy may become inflamed causing what is commonly referred to as stump appendicitis. Treatment with antibiotics may be attempted as an alternative to surgery; however, the vast majority of cases require definitive surgical excision of the remnant appendix. The authors propose that keeping this disease in the differential is important in reducing complications associated with delayed diagnosis.

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Book SynopsisGastric cancer is the fourth most common cancer in the world. Most gastric cancers are diagnosed in advanced stages, and the prognosis remains poor. The 5-year survival rate is 40-60% in eastern countries and around 25% in the west. Among advanced gastric cancer cases, peritoneal implantation is one of the most common forms of metastasis and around 14% of cases present peritoneal metastases at initial diagnosis, presenting a survival of 3-6 months. Until the early 1990s it was considered a terminal disease. But today these patients have some opportunities to be treated with curative intent or to prolong their life. Although the prognosis remains poor, there are some treatment options including cytoreductive surgery, neoadjuvant therapy, and some forms of intraperitoneal chemotherapy with or without hyperthermia. These are aggressive treatments, so we must be careful when selecting patients. Imaging and preoperative staging are also crucial in selecting patients for appropriate treatment. The surgical technique is described and a detailed demonstration video is available in the e-book version. New forms of treatment such as PIPAC and new scientific advances and future perspectives are discussed. This book is an update on this topic and attempts to provide an overview for all medical personnel involved in the treatment of these patients.Table of ContentsPreface; Epidemiology of gastric cancer; Role of imaging in peritoneal surface malignancies; Diagnosis and staging in advanced gastric cancer; Histopathological and molecular classifications of gastric cancer; Patient selection and preoperative considerations; Neoadjuvant and adjuvant therapy; Principles of cytoreductive surgery; Role of intraperitoneal chemotherapy.; Current role of PIPAC in peritoneal metastases of gastric origin; Scientific Advances and future perspectives; Index.

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Book SynopsisObesity is a multifactorial global epidemic with associated risk factors for an array of vascular, metabolic, psychological and economical consequences. Bariatric surgery has revealed a significant link between gastrointestinal metabolism and obesity that extends to resolution of many metabolic diseases including type 2 diabetes and cardiovascular disease risk. Bariatric surgery offers the most effective results and Roux-en Y gastric bypass (RYGB) is the most commonly performed bariatric surgery worldwide. The effective weight loss achieved by RYGB is thought to be caused by the re-arrangement of the gastrointestinal tract leading malabsorption and restriction of the ingested nutrients, and consequently resulting in alterations in the gut hormone levels. The first chapter of this book briefly summarises the current literature on the changes in the gastrointestinal hormones following RYGB. Chapter Two studies the role of bariatric surgery in the resolution of obesity and type 2 diabetes. Chapter Three discusses how to treat a type 2 diabetes patient post-bariatric surgery. The last chapter discusses the recent findings of the relationship between gastric bypass and four different skin disorders.

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Book SynopsisThere is an increase in specialisation within general surgery and now even within its sub specialties. Colorectal surgery is probably the largest of the subspecialties of general surgery, and one of the areas where trainees and consultant general /colorectal surgeons are least confident is in their understanding of the anatomy, physiological pathology and management of the anal canal and pelvis. Currently available there are books on the market centred around the general management of colorectal disease, but the time is now right for a definitive text on the anal canal and pelvis specifically. Table of Contents1. The Normal Anus.- 2. Anorectal Physiology.- 3. Imaging the Normal Anus.- 4. Surgical Treatment and Pathology: Normal Histology.- 5. Congenital Abnormalities of the Anus.- 6. Premalignant Conditions of the Anus.- 7. Malignant Conditions including Squamous Cell Carcinoma and Rare Cancers.- 8. Rectocele Pathophysiology and Presentation.- 9. Treatment: Rectocele.- 10. Incontinence- Causes and Pathophysiology.- 11. Incontinence Assessment: Physiology and Imaging.- 12. Surgical Treatments for Incontinence.- 13. Haemorrhoids – Anatomy , Pathophysiology and Presentation.- 14. Operative management.- 15. Benign Disease, Fissures, Presentation and Pathophysiology.- 16. Chronic Anal Fissure.- 17. Anal Sepsis: Anatomy, Pathophysiology and Presentation.- 18. Imaging of Anal Sepsis.- 19. Management of Anorectal Sepsis.- 20. Perianal Skin Conditions.- 21. Pruritus Ani. 22. Reconstruction of the Anus and Peri-Anal Region.

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Book SynopsisThis book is a topical review of issues the editors consider to be 'hot topics' and will be of interest to qualified consultant colorectal surgeons and those performing general surgery with an interest in colorectal surgery. In addition, the topics picked are likely to be ones that candidates taking the Intercollegiate Examination in General Surgery will be quizzed upon. It is not intended to be a textbook covering all aspects of colorectal surgery. Rather, it is meant to be an up-to-date view of current and probable near future advances. Frontiers in neoplasia, inflammatory bowel disease, anal disorders and management are covered by acknowledged experts, known to be active in the field. The implications of deep pelvic dissection and pouch surgery in males and females are sensitively explored. Each chapter contains three main sections entitled 'What is the problem/issue?', 'Where are we now?' and 'Where are we going?'. Referencing for the first two is key and current; the last section is speculative with the occasional reference. This volume should find a place on the coloproctologist's bookshelf as an exciting review of contemporary themes, complementing traditional textbooks.

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Book SynopsisThis book is both a lively introduction and a guidebook to those pioneers, most of them surgeons, who attempted to help their patients by extending the boundaries of their own knowledge and experience. In the 16 chapters of the book, an international group of authors have provided something of value to all those with an interest in surgical gastroenterology. Medical students and young trainees will come to understand the principles behind modern gastrointestinal surgery. Researchers will find insights and inspiration for their work and publications. Established surgeons and physicians will be rewarded with information that adds colour to their teaching, either on ward rounds or during formal lectures. Great care has been taken in choosing appropriate portraits and illustrations to bring these remarkable pioneers to life for the reader.Table of ContentsEarly Origins of Anatomy and Surgery; The Battle Against Infection; The Changing Tides in Oesophageal Surgery; The Arrival of Bariatric Surgery; Gastroduodenal Surgery; Surgery of the Liver and Billiary Tree; Surgery of the Pancreas; The Challenges of Intestinal Obstruction; Intestinal Reconstruction; The Story of Appendicitis; The Surgery of Inflammatory Bowel Disease; Evolution of Surgery for Colorectal Cancer; The Anus and Peri-Anal Conditions; Alimentary Tract Disorders in Infants and Children.

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Book SynopsisOffering comprehensive coverage of all diseases and conditions affecting the colon, rectum, and anus, Steele’s Colon and Rectal Surgery provides authoritative guidance on the full range of today’s operative procedures. Edited by Dr. Scott R. Steele, Chairman of the Department of Colorectal Surgery at the Cleveland Clinic, and section editors Drs. Justin A. Maykel, Amy L. Lightner, and Joshua I.S. Bleier, this new reference contains 81 concise, tightly focused chapters that take you step by step through each procedure, guided by the knowledge and expertise of key leaders in the field from across the world. Includes comprehensive coverage of the latest laparoscopic, robotic, and open diagnostic and surgical management techniques in all areas of colon and rectal surgery Each chapter includes insightful section editor commentary throughout and concludes with a senior editor commentary written by Dr. Steele Features a full-color design with hundreds of unique, detailed illustrations and photographs depicting the steps in today’s operative procedures Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

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Book SynopsisColorectal Surgery has continued to experience tremendous growth in both the community and academic settings over the past few years. The recent increase in demand for colorectal specialists has been fueled by an overwhelming number of applications to fellowship training programs, resulting in some of the most coveted and competitive positions. Furthermore, the accumulation of experience, knowledge, and wisdom from pioneers in the field, combined with major recent technological advances, has transformed the clinical management of diseases of the colon and rectum. Colorectal Surgeons have embraced advances ranging from minimally invasive approaches for complex problems to novel training methods for future generations. Additionally, we have spearheaded innovations in the management of colorectal cancer, pelvic floor disorders, diverticulitis, inflammatory bowel disease, and anorectal conditions. Despite these improvements, there remains a seemingly never-ending mixture of complex patient disease processes and complications resulting from the care of these patients. Even in cases where the technical challenges were managed successfully, complications or poor function may result in dramatic life-long consequences, reduced quality of life, as well as having economic implications. The American Society of Colon and Rectal Surgeons (ASCRS) is the premiere professional organization of Colon and Rectal Surgeons. Three editions of the ASCRS Textbook of Colon and Rectal Surgery have been published and have proved to be extremely valuable for their wealth of general information and knowledge, providing not only background information, but also specifics regarding the more complex situations that surgeons who treat patients with colorectal disease experience on a regular basis. An ASCRS manual was produced in in 2009 and 2014, each accompanying their original textbooks. This has been formed by abstracting the textbook into a bullet format; all figures and most tables were retained. The 3rd edition of the Textbook (published by Springer) included completely new chapters and authors. This 3rd edition of the Manual is indicated to conform to the new edition of the Textbook and incorporate newer information in the field of colon and rectal surgery. This Manual will serve as a very useful resource for physicians and researchers dealing with diseases of the colon and rectum. It will provide a concise yet comprehensive summary of the current status of the field that will help guide education, patient management and stimulate investigative efforts. All chapters were written and abstracted by experts in their fields and will include the most up to date scientific and clinical information.Trade Review“This book is written for senior surgical residents, colorectal surgery fellows, or practicing colorectal surgeons. … This is a nice book that will be a valuable resource to its readers. It is a short and efficient primer on a number of colorectal issues and will serve as a nice adjunct to the much larger textbook.” (Peter Nau, Doody's Book Reviews, May 17, 2019)Table of Contents

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Book SynopsisThis comprehensive text provides the reader with an in-depth understanding of laryngopharyngeal reflux (LPR), and presents a practical and readable evidence-based approach to the diagnosis and management of patients with this condition. It highlights options for management of those patients who fail to improve with traditional reflux treatment and assists in determining the next steps in the management of this population. Information is presented from an inter-disciplinary perspective, including input by otolaryngology, gastroenterology, speech pathology, and complementary/integrative medicine.The first section of the book is dedicated to understanding the fundamentals of laryngopharyngeal reflux as a condition. It begins with a review of the fundamental anatomy and pathophysiology of LPR and summarizes the landmark and most recent advances in the scientific understanding of this condition. Subsequent chapters delve into the typical symptoms and clinical presentations of patients, with information provided on cost-effective work-up strategies to confirm the diagnosis. The second section focuses on management of this condition. It begins with a thorough review of traditional medical management, including use of proton pump inhibitors, histamine receptor antagonists, neutralizing agents, low acid diet, alkalinizing agents, and alginates. Surgical management is reviewed as well, including partial and full fundoplication operations. It concludes with “non-traditional” treatment options for LPR, with chapters dedicated to voice therapy, probiotics, herbal therapies, and integrative East-West medicine approaches. Laryngopharyngeal Reflux Disease will be a definitive guide for otolaryngologists, gastroenterologists, speech pathologists, and general physicians with an interest in traditional and complementary/integrative treatments for patients with laryngopharyngeal reflux.Table of ContentsSection 1: Understanding and Recognizing LPR.- Laryngopharngeal Reflex: An Overview.- Approach to the Patient.- Commonly Confused Conditions.- Section 2: Treatment Options for LPR.- Lifestyle and Dietary Modifications.- Medical Management Options.- Surgical Management Options.- The Role of Voice Therapy.- Probiotic and Herbal Remedies.- Integrative East-West Medicine Approaches to LPR Symptoms.

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Book Synopsis​The first edition laid out the foundation with laparoscopic and robotic surgery utilizing the Da Vinci SI platform. Since then, many new advances in equipment and surgical techniques are becoming more popular. This second edition expands upon laparoscopic and endoscopic techniques and robotic surgery with the use of the new Da Vinci XI platform.This book bridges the gap between the practicing community of surgeons and the surgical innovators and provides a foundation for all classic and new techniques in minimally invasive colorectal surgery. By enhancing the surgical toolbox, the surgeon is able to progress from the novice to the master. Rather than describing the entire operative procedure by an individual author, this book compares operative steps of various technical difficulties throughout different chapters, thereby allowing the surgeon to tailor surgery to patient and surgeon`s own comfort level and experience. Chapters are written by a myriad of renowned experts in the field and discuss the major advances in advanced laparoscopic and endoscopic, robotic, and transanal minimally invasive surgical techniques. Great emphasis is placed on transanal total mesorectal excision (TaTME), which is dramatically changing the surgical approach to rectal resections. The second edition of Advanced Techniques in Minimally Invasive and Robotic Colorectal Surgery serves as a valuable resource to general surgeons, colon and rectal surgeons, minimally invasive surgeons, as well as residents and fellows.Table of Contents

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Book SynopsisThis volume provides a concise yet comprehensive overview of advanced techniques in interventional endoscopy beyond ERCP and EUS. Comprised of sections on endoscopic resection (including EMR, ESD, STER and EFTR), bariatric endoscopy, endoscopic myotomy (POEM, GPOEM, ZPOEM and PREM), endoscopic anti-reflux therapies, endoscopic tissue apposition, and advances in interventional EUS, the text highlights indications and technical details, assesses safety and efficacy, and provides quality metrics and training pathways for these endoscopic procedures. The book is also accompanied by multiple photos and videos illustrating these endoscopic techniques. Written by world renowned experts in the field, Gastrointestinal Interventional Endoscopy: Advanced Techniques is a valuable resource for gastroenterologists and surgeons interested in the latest advances in interventional endoscopy.Table of ContentsPart I Endoscopic Resection1 Endoscopic Lesion Recognition and Advanced Imaging ModalitiesJorge D. Machicado, Jennifer Kolb, Sachin B. Wani2 Endoscopic Mucosal Resection of the EsophagusSamuel Han, Hazem Hammad3 Gastric and Duodenal Endoscopic Mucosal ResectionRommel Romano, Pradermchai Kongkam4 A Pragmatic Approach to Complex Colon PolypsMichael X. Ma, Michael J. Bourke5 Endoscopic Tools and Accessories for ESD Calvin J. Koh, Dennis Yang, Peter V. Draganov6 Esophageal ESD Lady Katherine Mejía Pérez, Seiichiro Abe, Raja Siva, John Vargo, Amit Bhatt7 Gastric ESDTakuji Gotoda8 Colonic ESDVikneswaran Namasivayam, Yutaka Saito9 Endoscopic Full Thickness Resection (EFTR) and Submucosal Endoscopic Resection (STER)Mingyan Cai, Marie Ooi, Pinghong Zhou10 EMR Versus ESD: Pros and ConsVijay Kanakadandi, Mojtaba Olyaee, Amit Rastogi 11 Training and Competency in Endoscopic ResectionDaniel S. Strand, Andrew Y. WangPart II Bariatric Endoscopy12 Intra-gastric Balloons and Aspiration TherapyChetan Mittal, Shelby Sullivan13 Endoscopic Sleeve Gastroplasty (ESG)Gontrand Lopez-Nava, Inmaculada Bautista-Castaño14 Emerging Endoscopic Therapies for Weight Loss Thomas J. Wang, Marvin Ryou15 Endoscopic Therapy of Post-Bariatric Surgery Strictures, Leaks and FistulasFilippo Filicori, Lee L. Swanström16 Endoscopic Management of Weight RegainEric J. Vargas, Andrew C. Storm, Fateh Bazerbachi, Barham K. Abu DayyehPart III Endoscopic Myotomy17 POEM: Pre-procedural work-up and IndicationsJoseph Rayfield Triggs, John E. Pandolfino18 Peroral Endoscopic Myotomy: Endoscopic TechniquesChetan Mittal, Mihir S. Wagh19 POEM: Efficacy, Safety, Training and Competency Juergen Hochberger, Volker Meves20 Endoscopic Myotomy for Zenker’s Diverticulum (Z-POEM) Alessandro Fugazza, Roberta Maselli, Alessandro Repici21 Per-oral Endoscopic Pyloromyotomy (G-POEM) and Per-rectal Endoscopic Myotomy (PREM) Amol Bapaye, Amit MaydeoPart IV Endoscopic Anti-Reflux Therapies22 History of Endoscopic Anti-reflux Therapies - Lessons Learned Zaheer Nabi, D. Nageshwar Reddy 23 Transoral Fundoplication for Treatment of Gastroesophageal Reflux DiseasePier Alberto Testoni, Sabrina Gloria Giulia Testoni, Giorgia Mazzoleni, Lorella Fanti24 Radiofrequency Ablation and Anti-Reflux Mucosectomy for Gastroesophageal Reflux DiseaseBryan Brimhall, Amit Maydeo, Mihir S. Wagh, Hazem HammadPart V Endoscopic Tissue Apposition25 Techniques for Endoscopic SuturingOlaya I. Brewer Gutierrez, Stuart K. Amateau26 Endoscopic Clips and GluesRoupen Djinbachian, Daniel von RentelnPart VI Advances in Interventional EUS27 Interventional EUS: PancreasVinay Dhir, Ankit Dalal, Carmen Chu 28 Interventional EUS: Bile Duct and GallbladderAnthony Yuen Bun Teoh, Kenjiro Yamamoto, Takao Itoi29 Interventional Vascular EUSJason B. Samarasena, Kyle J. Fortinsky, Kenneth J. Chang

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Book SynopsisThis atlas provides a concise yet comprehensive overview of high-resolution manometry, impedance and pH monitoring. Through instructive text and over 130 high-yield images, the atlas describes the basic principles of esophageal, antroduodenal and anorectal high-resolution manometry, reviews both normal and pathologic findings on manometry, covers technical aspects of pH monitoring and impedance, and outlines advances in equipment, software, and diagnostic guidelines.Written by experts in the field, Atlas of High-Resolution Manometry, Impedance, and pH Monitoring is a valuable resource for gastroenterologists and other clinicians and practitioners who work or are interested in the GI motility field. Table of Contents1 Introduction to High-Resolution Manometry and Impedance 2 Esophageal Manometry3 Antroduodenal Manometry 4 Anorectal Manometry 5 Basic Principles of Ambulatory pH monitoring and Impedance

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Book SynopsisThis clinical casebook provides a comprehensive yet concise state-of-the-art review of gluten-associated disorders. Presented in a case-based format, the casebook reviews the overall management of celiac disease (from seronegative through classical to refractory disease) as well as non-celiac gluten/wheat sensitivity, with an emphasis on gastrointestinal and extra-intestinal manifestations of these disorders. Specific topics presented in these cases include, for instance, dermatitis herpetiformis, celiac disease and the liver, non-responsive celiac disease, celiac crisis, overlap with functional gastrointestinal disorders, and fructan intolerance. Two chapters written by expert dieticians share their experience in managing celiac disease and gluten/wheat sensitivity. Written by international experts in the field, Diagnosis and Management of Gluten-Associated Disorders: A Clinical Casebook is a valuable resource for both adult and pediatric gastroenterologists, hepatologists, primary care physicians, dermatologists, registered dieticians, trainees, and researchers interested in gluten-associated disorders.Table of ContentsPreface1. From Classical to Non-Classical Celiac DiseaseNir Bar, MD, Dana Ben Ami Shor, MD, Guy A. Weiss, MD2. Dermatitis HerpetiformisTeea Salmi, Kaisa Hervonen3. Celiac Disease and The LiverBeshoy Yanny MD, Jasleen Kaur Grewal MD, Angela Doan NP, Vijeta Kailash Vaswani, MPH4. Pediatric Celiac DiseaseHilary Jericho, MD and Stefano Guandalini, MD5. Celiac Disease and Women’s HealthCarolina Ciacci, Fabiana Zingone6. Gluten Challenge in Gluten-Associated DisordersRafael Mendo-Lopez , Shakira Yoosuf , Daniel Leffler7. Seronegative Celiac DiseaseSuneeta Krishnareddy MD MS, Benjamin Lebwohl MD MS8. Non-Responsive Celiac DiseaseIsabel A. Hujoel, Alberto Rubio-Tapia9. Type I Refractory Celiac DiseaseMarjorie M Walker, BMBS, Michael D Potter10. Type II Refractory Celiac DiseaseAdam C. Bledsoe, MD, Joseph A. Murray, MD11. Enteropathy-Associated T-cell LymphomaKarlton Wong, Monica Mead12. Celiac CrisisJonas Zeitz, MD and Peter HR Green, MD13. The Role of Capsule Endoscopy in Celiac DiseaseNeil Marya, Stephen Kim14. Between Functional Gastrointestinal Disorders and Celiac DiseaseAdrienne Lenhart, M.D. and Lin Chang, M.D.15. The Dietitian Role in Celiac DiseaseJanelle Smith MS RDN CEDRD16. Non-Celiac Gluten SensitivityGiulia Catassi, Loris Naspi, Carlo Catassi17. The Dietitian Role in Non-Celiac Gluten SensitivityNancee Jaffe MS RDN18. Fructan IntoleranceElizabeth B. Hastie and Sheila E. Crowe

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Book SynopsisThe book encompasses the different concepts and designs using magnets for surgical purposes. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. The text reviews new data about interventions in all medical and surgical fields. Written by experts in their fields, topics focus on endoluminal and laparoscopic operations, techniques from vascular and GI anastomosis. The book demonstrates the use of magnets to treat a variety of diseases such as reflux, back pain, and fecal incontinence. The reader will learn how to retract and gain exposure, dissect tissue planes, achieve hemostasis, and create anastomosis in a totally different way. Physical properties of external surface and internal magnets are discussed. The authors emphasize the importance of partnering with industry leaders to develop novel surgical tools.By harnessing the power of attraction, the energy and might of magnets, Magnetic Surgery serves as a valuable resource for clinicians, surgeons and researchers in biomedical engineering interested in this form of energy and physical metal properties. In utilizing these properties, the book seeks to improve surgical outcomes of patients worldwide.Table of ContentsIntroduction – Ideas and People Leading to Successful Products for Patient Care Leading to Magnetic Surgery- Physical Properties, Toxicity, and Physiological Effects of Magnets.- History of Magnets Used in Surgery.- Magnetic Interventions for Gastro-Esophageal Reflux.- Use of Magnets for Double-J Ureteral Stents.- Magnets for Colorectal Anastomosis.- Magnets for Fecal Incontinence.- Magnets for Urinary Incontinence.- The Use of Magnets in the Treatment of Congenital Disorders.- Use of Magnets in Flexible Endoscopy.- Magnetic Retraction for Laparoscopic Cholecystectomy and Other General Surgical Interventions.- Magnetic Retraction for Laparoscopic Sleeve Gastrectomy and Other Bariatric Procedures.- Magnetic Vascular Anastomosis.- Laparoendoscopic Magnetic Gastrointestinal Anastomosis.- Endoscopic Magnetic Bowel Anastomosis.- Magnetic Compression Anastomosis and Magnetic Compression Revision for Stenosis.- Use of Magnetically Controlled Growing Rod Implants for the Spine.- Magnetic Anal Sphincter for Fecal Incontinence.- Magnetic Satiety System: The Use of Magnets to Assist in Combating Obesity.- Future / Research in Magnetic Surgery.

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Book SynopsisThis book provides a practical overview of the treatment and management of celiac disease. It examines new data which can be merged with clinical aspects to provide a global perspective for the busy clinician. The disease represents 1% of the population and often goes unnoticed for a long time; however, this book aims to reduce the instance of misdiagnoses of symptoms by providing clear guidance in a single book, with contributions from esteemed experts in the field. Advances in Celiac Disease - Improving Paediatric and Adult Care addresses the clinical characterisation of the disease, in both paediatric and adult populations. The clinical symptoms are clearly defined as well as treatment options and follow-up. This book will be an essential resource for clinicians seeking a clear, concise resource to identifying, treating, and managing celiac disease in both adults and children. Table of ContentsWhat is Celiac disease.- New Diagnostic Criteria for Children and Adolescents.- Classical Clinical Forms in childhood.- Extra-intestinal clinical forms in childhood.- Specific features of Celiac Disease in adults.- Epidemiology.- Importance of Histological Diagnosis.- Value of genetic markers.- Value of serological markers.- Autoimmunity and Celiac Disease.- Follow-up of pediatric patients.- Transition of the celiac patient: from the pediatrician to the adult gastroenterologist.- Follow-up of Adult patients.- Quality of Life and Celiac Disease.- New Research Fields in Celiac Disease.- Primary Health Care Prevention of Celiac Disease.- The Gluten-free Diet.- New therapeutic strategies.- Non celiac sensitivity to Gluten.

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Book SynopsisThis book provides a concise overview of several critically important techniques and their applications within Laparoscopic Common Bile Duct Exploration (LCBDE). LCBDE is rapidly emerging as the preferential management option for treating patients with common bile duct (CBD) stones. Chapters within this book describe how this technique can be applied to manage patients with concomitant gallstones, which aims to increase the exploration of the CBD via the transcystic route. Particular mention is made for the use of energy devices to enable stone fragmentation within the bile duct also known as Lithotripsy-Assisted Bile duct Exploration by Laparoendoscopy (LABEL). Guidance is also provided on how to set-up an acute biliary service which can offer the single-stage management of concomitant gallstones and choledocholithiasis. The concepts of ‘Leveraging Access to Technology and Enhanced Surgical Techniques (LATEST)’ in LCBDE and ‘Biliary Surgery 2.0’ as the framework through which these techniques can be further enhanced are analysed. Laparoscopic Common Bile Duct Exploration features insight into how to perform these increasingly important procedures successfully and set-up a service within institutions that are yet to provide it. Therefore, it is a valuable resource for all medical professionals involved in the care of these patients.Table of ContentsHistory of biliary surgery.-The first cholecystectomy.- The first choledochotomy.- History of common bile duct imaging.- Technique of CBD exploration in the 60’s 70’s.- The arrival of ERCP.- Approach to the cbd stones in the 80’s.-The revolution in the nineties: The laparoscopic cholecystectomy and bile duct exploration.- Review of the evidence against and in favour of LC-IOC±LCBDE.- Our technique & equipment needed.- Equipment and kit needed for LCBDE.- Surgical technique for LCBDE.- Laparoscopic ultrasound.- Different surgical scenarios and its specific management.- Different surgical scenarios.- CBD and CD both non-dilated.- CD Dilated & CBD non-dilated.- CD non-dilated & CBD Dilated.- CD & CBD both dilated.- The impossible hilum: The transinfundibular approach.- The closure after the access to the CBD.- Closure over T -tube.- Closure over antegrade stent.- Primary closure.- Closure with transcystic drain.- Bilioenteric anastomoses.- The LABEL technique.- Our experience with LCBDE in more than 450 cases.- The evolution to Biliary Surgery 2.0.- Our cases.-Failure to clear the duct.- Morbidity.- Closure after exploring CBD.- T tube vs antegrade stent.-Primary closure.- Increase in the use of transcystic approach.- The transcystic vs the TD access.-management of Type II Mirizzi syndrome.- The impact pf LCBDE in a general surgical department.-Bile duct exploration 2.0 .-Training in LCBDE.

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Book SynopsisThis extensively revised second edition of this essential work provides a comprehensive overview of Gastroesophageal Reflux (GER) in children. It contains detailed insight into the epidemiology and pathophysiology of the condition. Relevant diagnostic methods and treatment techniques are also covered. Heavily revised chapters discuss issues associated with GER in special patient populations and current approaches to GER diagnosis and management. New chapters cover relevant aspects of the microbiome, how nutrition can be key to successful treatment and the adverse effects of the latest therapeutic drugs presently available. Colic in infants, and differential diagnoses in eosinophilic esophagitis are also described. The first part of the book is dedicated to introducing the condition, discussing epidemiology, symptoms and diagnosis. This is followed by addressing issues of the condition encountered in special patient populations such as in preterm infants, apnea, neulorogic patients and cystic fibrosis, among others. The final part of the book is dedicated to therapeutic approaches from medication to surgery and alternative approaches such as complementary medicine and hypnotherapy. The approaches and challenges in endoscopy are also detailed.Gastroesophageal Reflux in Children, Second Edition is edited by a leading world expert in the topic and written by a global team of authors from a range of associated disciplines, making the work a critical resource for pediatricians, gastroenterologists to pulmonologists, otolaryngologists and neurologists.Table of Contents

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Book SynopsisThis book is based on the proceedings of the Enteric Nervous System conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility. The book focuses on methodological strategies and unresolved issues in the field and explores where the future is heading and what technological advances have been made to address current and future questions. The Enteric Nervous System II continues in the tradition of a popular earlier volume which covered the previous meeting. Many of the same authors are contributing to this new volume, presenting state-of-the-art updates on the many developments in the field since the earlier meeting. The coverage include a wide range of topics, from structure and function of the enteric nervous system through gut motility and visceral pain. The author team includes long-established authorities who significantly contributed to the advances in ENS research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field. Table of Contents Luminal Chemoreceptors and Intrinsic Nerves- Key Modulators of Digestive Motor Function Comparative and evolutionary aspects of the ENS Exploring synaptic transmission in the ENS: electrophysiology, functional studies and modelling Mucosal Serotonin Ca2+ signaling in Interstitial cells of Cajal: The mechanistic basis for many GI motility behaviors Identifying types of neurons in the enteric nervous system Clinico-Pathological Features of severe gut dysmotility Purinergic signaling in the ENS Myogenic and neural control in concert colonic response to physiological and chemical stimuli Molecular targets to alleviate enteric neuropathy and gastrointestinal dysfunction The emerging role of the gut-brain microbiota axis in neurodevelopmental disorders A view on how enteric neurons monitor luminal content Interaction of the microbiota and the developing ENS Influence of the circadian rhythm on enteric nervous system function Mechanosensitive Enteric Neurons (MEN) at work Neurogenetic investigation of the ENS and gut motility The shaggy dog story of enteric signaling: serotonin, a molecular megillah Contribution of enteric neuroglial remodelling to inflammatory bowel disease and cancer evolution Examining cellular metabolism in the enteric nervous system Embryonic development of motility: a bottom-up approach to the workings of the intestine Quantitative analysis of intestinal movements with spatiotemporal maps The roles of Mas related G-protein coupled receptors in the gut Refining Enteric Neural Circuitry by Quantitative Morphology, Transcriptomics and Function in Mice” Extrinsic modulation of enteric circuits that regulate colon function in health and disease Activating and Modeling ENS Circuits in Mouse Colon Neurons, macrophages and glia: the role of intercellular communication for gut motility Modelling development of the ENS: What's been done and what's next Epithelial 5-HT4 receptors as a target for treating constipation and colitis Activity in Enteric Neural circuits underlying propulsion Contribution of the ENS to autoimmune diseases and irritable bowel syndrome

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Book SynopsisThis book provides extensive information on the duodenal switch and all of its derivatives. The number of procedures performed is progressively increasing, as cases of obesity are on the rise and patients’ body mass index (BMI) is getting higher. It discusses all the techniques involved in the duodenal switch procedure and its derivatives used in the primary and revision situations. Readers will learn what the procedure can offer not only in terms of weight loss, but also its potential with regard to metabolic diseases, since some data indicates that the duodenal switch may lead to rapid resolution of diabetes and other comorbidities. The work is divided into three parts, the first of which provides an overview of the duodenal switch, its history, mechanisms of action and reasons for performing it. Part II covers patient selection, risk assessment, complications and different techniques regarding weight loss surgery. In addition, there are chapters on nutrition and psychological aspects. Lastly, the chapters in Part III address patient selection and preoperative and postoperative care in metabolic and diabetes type 2 surgeries. The most important information on the duodenal switch is gathered in a single volume and includes its benefits for metabolic diseases. This book will give healthcare professionals new confidence with regard to this procedure and may serve as a reference guide not only for the bariatric community (surgeons, PA, ARNP, nutritionists) but also for teaching new residents and fellows.Table of ContentsPart I – Introduction 1. A Brief History of the Duodenal Switch 2. Duodenal Switch. Mechanisms of functioning 3. Duodenal Switch and Its Derivatives 4. Primary Single Anastomosis Duodenal Switch: Perspective from a Lengthy Experience 5. Duodenal Switch and Its Derivatives in Bariatric and Metabolic Surgery Part II - Weight Loss Surgery 6. Pathophysiology of the cardiometabolic alterations in obesity 7. Pathophysiology of bile acid regulation 8. Nonalcoholic steatohepatitis (NASH) 9. Patient Selection 10. Psychological and Psychiatric Work Up 11. Nutritional, Behavioral, and Support for Duodenal Switch 12. Preoperative endoscopy 13. Postoperative care 14. Preoperative Testing and Counseling 15. Risk Assessment and Reduction 16. Airway Evaluation and Management 17. Patient Positioning and Positioning for Bariatric Surgery 18. Intraoperative Monitoring Of The Morbidly Obese Patient 19. Method of anesthesia: gas selection and adjunct medications 20. Regional Anesthesia in Bariatric Surgery 21. Multimodal Analgesia in Bariatric Surgery 22. Anatomical Considerations 23. Robotic Duodenal Switch and SADI-S: Technical Aspects 24. Laparoscopic Biliopancreatic Diversion with Duodenal Switch: Surgical technique 25. SADIS - Technical details 26. Technical Aspects of Single Anastomosis Duodenal Switch-SIPS Version 27. Duodenal Bipartition or Side-to-Side Duodeno-Ileostomy. Rationale and Technical Details 28. Duodenoileal anastomosis with handsewn tehcnique 29. Circular Anastomosis in Duodenal Switch 30. Duodenoileal anastomosis with linear stapler technique 31. Staged Duodenal Switch for High-Risk Patients 32. Duodenal Switch, SADI and SIPS in Adolescent 33. Duodenal Switch (DS), Single Anastomosis Duodeno-Ileal bypass (SADI) and Stomach Intestinal Pylorus-Sparing (SIPS) Surgery in the Elderly 34. Right Gastric Artery Ligation: The Brazilian Results 35. Surgery Failure: what are the options? 36. Causes of Weight Regain After Duodenal Switch and its Derivatives 37. Revisional Surgery for Weight Regain 38. Conversion of Sleeve Gastrectomy to Duodenal Switch and SADI-S 39. Gastric Band Revision to Duodenal Switch 40. Endoscopic Treatment of Weight Regain in Duodenal Switch 41. Conversion of Gastric Bypass to Duodenal Switch 42. Management of Duodenal Stump blowout 43. Duodenoileal anastomosis testing 44. Closing the mesenteric defects 45. Preventing Surgical Complications 46. Malabsorbative complications 47. Postoperative Psychological Assistance 48. Surgical Management of Leaks 49. Internal Hernias and Bowell Obstruction 50. Management of Portal Vein Thrombosis Following Bariatric Surgery 51. Gallstones and Choledocholithiasis 52. Hyperinsulinemic postprandial hypoglycemia after duodenal switch 53. Diarrhea after Duodenal Switch: Medical and Surgical Management 54. Endoscopic Treatment of Complications 55. Global analyisis of our experience with hypoabsortive tecnique: > 500 cases DS vs SADI-S 56. Body Contouring after Duodenal Switch 57. Bariatric Surgery Population in the ICU 58. Bariatric Emergencies For The General Surgeon 59. Robotic bariatric surgeon training Part III - Metabolic and Diabetes Type 2 Surgery 60. Mechanisms of control of diabetes 2 with duodenal switch 61. The Evolution of Single anastomosis Duodenal Switch 62. Metabolic Syndrome Control and the influence of hormonal changes post-Duodenal Switch (DS) 63. Staged Duodenal Switch for High-Risk Patients 64. Duodenal Switch in Patients with Metabolic Syndrome 65. Duodenal Switch (DS) for the Surgical Treatment of Diabetes and Metabolic Disease 66. Postoperative care 67. Metabolic Syndrome and the Influence of Bile Acids

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Book SynopsisThis open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, ultrasound, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. IDKD books are extensively re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their speciality. Table of ContentsEmergency radiology of the abdomen and pelvis (inkl. trauma).- Imaging infectious disease of the abdomen (including COVID).- Staging and monitoring of oncologic disease with emphasis on standardized reporting and hybrid imaging.- Benign and malignant diseases of the colon and rectum.- Retroperitoneal masses.- Diffuse liver disease.- Focal liver disease.- Diseases of the gall bladder and biliary tree.- Diseases of the pancreas.- Adrenal disease.- Benign and malignant renal disease.- Update on immunotherapies: the role of the radiologists in the era of precision medicine.- Benign disease of the uterus.- Malignant disease of the uterus.- Adnexal disease.- Prostate MRI.- Pathways for spread of disease in the abdomen.- Small bowel disease.- Congenital and acquired pathologies of the pediatric gastro-intestinal tract.- Congenital and acquired pathologies of the pediatric uro-genital tract.

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Book SynopsisThis is an open access book. Colorectal surgery is one of the most performed procedures in dedicated colorectal and general surgery units worldwide. In the last two decades, the minimally invasive laparoscopic approach has become very popular worldwide, attracting great interest among patients (lower risk of infection, less pain, and faster recovery) and demonstrating excellent oncological results. Technology is improving rapidly, offering revolutionary innovations, particularly with the advent of robotic surgery, which offers important advantages over laparoscopy for both surgeons and patients: improved ergonomics, wristed instruments, and a better vision. These advantages may be particularly useful for more complex and challenging situations (complete mesocolic excision, low rectal cancer, one-stage treatment of colorectal and liver metastases, etc.), translating into potential improved surgical and oncological results. Although several books have been published on the subject, the great interest in robotic surgery makes it mandatory, in our opinion, to have a general update in view of the latest technical innovations and the results of the most relevant and recent literature. The book is divided into chapters dealing with the different colorectal segments with their robotic surgical operations and specific technical variants. The new frontiers of benign and emergency colorectal diseases are also considered, as well as the new robotic platforms recently introduced in the healthcare market. Some of them, such as the da Vinci SP single port device, may represent a revolutionary approach for this surgery. Training and cost aspects were also considered.Table of Contents1 The tale of two cities: the development of trauma and acute care surgery.- 2 Organization and training in trauma and acute care surgery in Italy.- 3 The development of a regional trauma registry.- 4 Quality assessment in acute care surgery.- 5 Diagnostic protocols in trauma care.- 6 Damage control surgery. An Update.- 7 Damage control resuscitation and massive transfusion.- 8 REBOA in exanguinating torso haemorrhage.- 9 Definitive Care of abdominal solid organ injuries.- 10 Trauma to the chest: the role of trauma surgeon.- 11 Abdomino-pelvic trauma.- 12 The open abdomen: indications and techniques.- 13 Entero-atmospheric fistula: a challenge of acute care surgery.- 14 Operative endoscopy in acute care surgery.- 15 Point of Care Ultrasounds in acute care surgery.- 16 Large bowel emergencies.- 17 Biliary emergencies.- 18 Step-up approach in acute pancreatitis.- 19 Source control in abdominal sepsis.- 20 Laparoscopy in acute care surgery.- 21 Caustic injuries.

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Book SynopsisThis text and the terminology developed by the Papanicolaou Society of Cytopathology (P.S.C.) represents an important advance in the field of pancreaticobiliary cytopathology. This textbook/atlas is designed to present a comprehensive and state of the art approach to the cytologic diagnosis and reporting of pancreaticobiliary lesions. Chapters address each of the diagnostic categories defined by the P.S.C. The definition of each category along with the clinical pathologic entities contained within the category are discussed along with specific cytologic criteria for inclusion of a cytologic specimen within the category. Each chapter is lavishly illustrated demonstrating diagnostic criteria and examples of lesions contained within the category. Additionally, appropriate ancillary testing is discussed and where appropriate illustrated. Each chapter concludes with a discussion of appropriate management as well as estimates of malignancy risk for the category.The Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology: Definitions, Criteria, Ancillary Testing and Management will provide the reader with a unified approach to diagnosing and reporting interpretations of cytologic specimens obtained from the pancreaticobiliary tract. This text/atlas will serve as a reference guide for pathologists, surgeons, endoscopists and radiologists. Table of Contents1. Overview of Diagnostic Terminology and Reporting2. Category I. Non-Diagnostic3. Category II. Negative (for Malignancy)· Acute Pancreatitis· Chronic Pancreatitis· Autoimmune Pancreatitis· Pseudocyst· Lymphoepithelial Cyst· Splenule/Accessory Spleen4. Category III. Atypical5. Category IV: Neoplastic: Benign· Serous Cystadenoma· Neuroendocrine Microadenoma· Lymphangioma6. Category IV: Neoplastic: Other· Pancreatic Neuroendocrine Tumor· Solid-Pseudopapillary Neoplasm· Neoplastic Mucinous Cysts (Intraductal papillary mucinous neoplasm (IPMN) and Mucinous cystic neoplasm (MCN)7. Category V. Suspicious (for Malignancy)8. Category VI. Positive or Malignant· Ductal adenocarcinoma and variants· Acinar Cell Carcinoma· High-grade neuroendocrine carcinoma· Pancreatoblastoma· Lymphoma· MetastasesAppendix A: Template for Cyst DiagnosisAppendix B: Mucinous EtiologyAppendix C: Useful Ancillary Tests

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Book SynopsisThis volume presents a concise yet comprehensive overview on all facets concerning the complications of cirrhosis. Structured in three sections, the book reviews the natural history of cirrhosis, the diagnostic and predictive tools available to assess the disease, complications, and treatment options such as liver assist devices and transplantation. Topical concerns in the management of patients with cirrhosis are also addressed, including issues pertaining to the delivery of quality care in this patient population.Written by experts in their fields, Complications of Cirrhosis: Evaluation and Management serves as a valuable resource for practitioners and physicians-in-training on the subject of cirrhosis.Trade Review“It is a very informative resource on cirrhosis and the associated disease process. … It is written for those in the field of gastroenterology and practitioners who encounter patients with this disease process on a daily basis. … This book will prove helpful in day-to-day practice when patients present with complicated situations related to cirrhosis. It will be of use for quick reference as well as to build an understanding of the overall disease state and management.” (Matthew M. Lute, Doody’s Book Reviews, April, 2016)Table of ContentsPart 1: Diagnosing and prediction – Getting it right now, predicting it right in the futureChapter 1: Pathogenesis and Evolution of Liver Fibrosis: Cirrhosis or Cirrhoses?Francesca Saffioti, Massimo PinzaniChapter 2: Natural History of CirrhosisGuadalupe Garcia-TsaoChapter 3: Prediction of Complications of Cirrhosis: Molecular BiomarkersMar Coll, Elsa Solà, Pau Sancho-BruChapter 4: Predictors of Clinical Complications of CirrhosisJoel P. Wedd, Avash Kalra, Scott W. BigginsChapter 5: Non-Invasive Markers of Fibrosis in the Assessment of CirrhosisNikhiel B. Rau, Nezam AfdhalChapter 6: Diagnosis of cirrhosis: ImagingSumit Kumar, Sumeet K Asrani, Jayant TalwalkarChapter 7: Measurement of Portal Pressure and Transjugular Liver BiopsyJuan G Abraldes, Philippe Sarlieve, Puneeta TandonPart 2: Current Management Strategies of the Complications of CirrhosisChapter 8: Reversal of CirrhosisGemma Odena, Eva Stein, Ramon BatallerChapter 9: Esophageal Varices: Primary and Secondary ProphylaxisHumberto Gonzalez, William SanchezChapter 10: Acute Variceal BleedingÀngels Escorsell, Virginia Hernández-Gea, Juan C. García-PagánChapter 11: Gastric and Ectopic VaricesDaniel Schmidt, P Aiden McCormickChapter 12: Portal Hypertensive Gastropathy and Gastric Antral Vascular Ectasia (GAVE)Mary Drinane, Vijay H. ShaChapter 13: Ascites and Refractory AscitesAngelo Paredes, Arun J. SanyalChapter 14: Hyponatremia in CirrhosisElliot B. Tapper, Andrés CárdenasChapter 15: Hepatorenal syndromeElsa Solà, Pere GinèsChapter 16: Hepatic EncephalopathyAnkit V. Patel, Jasmohan S. BajajChapter 17: Cirrhotic Cardiomyopathy: Pathogenic Mechanisms and Management StrategiesSam LeeChapter 18: Hepatopulmonary syndromeMichael Fallon, David GoldbergChapter 19: Portopulmonary HypertensionMichael Krowka, Rodrigo Cartin-CebaChapter 20: Portal Vein ThrombosisDominique-Charles VallaChapter 21: Coagulation Disorders in Patients with CirrhosisPatrick NorthupChapter 22: Hepatocellular CarcinomaLewis RobertsChapter 23: CholangiocarcinomaWilliam C. Palmer, Denise M. HarnoisChapter 24: Bacterial Infections in Patients with CirrhosisThierry Gustot, Richard MoreauChapter 25: Acute-on-Chronic Liver failure (ACLF)Vicente Arroyo, Javier FernandezChapter 26: Liver support systemsMansoor Bangash, Banwari Agarwal, Rajiv JalanChapter 27: Liver TransplantationNizar A. Mukhtar, Oren K. FixChapter 28: Assessment and management of the patient with cirrhosis undergoing surgeryDavid P. Nunes, Surakit PungpapongChapter 29: Promoting a Healthy Lifestyle, Managing Hyperlipidemia, Diabetes Mellitus, Hypertension and Immunizations in Patients with CirrhosisDavid P. Nunes, Surakit PungpapongChapter 30: Malnutrition in Patients with CirrhosisJaime Aranda-MichelChapter 31: Bone disease in Patients with CirrhosisAlbert Parés, Núria GuañabensPart 3: Cost, Quality and End-of-Life Care in CirrhosisChapter 32: The Economic Cost of CirrhosisFasiha Kanwal, Michael VolkChapter 33: Delivering Quality Care to Patients with Cirrhosis: A Practical Guide for CliniciansMichael Volk, Fasiha KanwalChapter 34: Quality of life issues for patients with cirrhosisLinda Henry, Zobair YounossiChapter 35: Palliative Care in CirrhosisMaria Yataco, Robert Shannon, Andrew P. KeavenyChapter 36: Ethical Issues in End Stage Liver Disease: A Framework for Assessment and the ChallengesStephen Chris Pappas

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Book SynopsisThis comprehensive manual discusses the many aspects of inflammatory bowel disease (IBD), providing relevant information along with practical guidance. The reader is also directed to additional resources for extra and current information. This book comes at a time when the number of people suffering from the two major forms of IBD, ulcerative colitis (UC) and Crohn’s disease (CD), is rising around the globe. Despite their huge impact on daily life and health economics, these diseases are not fully understood, and diagnosis and treatment remains a significant challenge. IBD nurses are increasingly recognised as key clinicians within the multidisciplinary team caring for people with IBD. Through experience and specialist knowledge IBD nurses provide timely support, advice, and treatment for people living with this unpredictable condition. IBD nurses are also well placed to liaise with the wider team, developing patient centred services which best fit their local health framework. The combined international expertise and accessible guidance here will equip nurses, or any clinician wanting to increase their competence in IBD management. Thereby this manual aims to contribute to the optimisation of IBD care throughout the world.Table of ContentsI.IBD Foundations: Anatomy and Physiology.- Epidemiology.- Aetiology, Pathophysiology and Localisation.- II. Diagnosis, Assessment and Monitoring: Clinical Assessment.- Endoscopy.- Lab.- Radiology.- Histopathology.- Monitoring.- Differential Diagnosis.-III.Managing IBD: Medical Management 1: General.- Medical Management 2: Conventional.- Medical Management 3: Biological.- New Therapeutic Treatments.- Antibiotics and Microflora (FMP).- Risks and Side-Effects of Medical Therapy.- Surgical Management.- Short Bowel Syndrome.- Alternative Therapies.- IV. Complications and Comorbidities: EIMs.- Penetrating CD and Fistulae.- Opportunistic Infections.- Cancer.- V. The Patient in... Newly Diagnosed Patient.- Fertility, Pregnancy and Lactation.- Young IBD.- Elderly.- Patient Priorities.- Dietary Management.- Stoma.- Pouch Care.- Adherence.- Constipation.- VI. Lifestyle Issues: Travel and Vaccination.- Smoking and Drugs.- Stress and Psychological Support.- Communication Skills.- Sport.- Sex and Intimacy.- Patient Support Groups.- VII. Research: Clinical Studies.- Nursing Research.- VIII. IBD Nursing: Training and Education.- E-health.- In Patient Care.- Nursing Support and IBD Networking.- Advice Lines.- Clinics.- Maintaining and IBD Nurse Service.- IBD Nurse Within the MDT.

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Book SynopsisThis edition of the SAGES Manual of Hernia Surgery aligns with the current version of the new SAGES University MASTERS Program Hernia Surgery pathway. This manual serves as a curriculum for participants in the MASTERS Program as well as a modern text on hernia surgery for all learners. Hernia surgery is one of the fastest developing fields in general surgery today. There have been rapid advancements in hernia techniques in recent years, making most prior texts on the subject obsolete. These advancements involve significant evolution in both the techniques and strategies for hernia repairs, as well as the tools used to achieve these means. This text thoroughly addresses the multiple component separation techniques and options for locations of mesh repairs. It also discusses the revolution of hernia repair being facilitated by robotic surgery, which allows increased access to minimally invasive techniques for surgeons and thus increased access to minimally invasive surgical repairs for patients. This manual will be a valuable resource for interested surgeons to understand the variety of potential approaches to individual hernias, and to individually tailor the care of the hernia patient.Trade Review“This will be used by trainees at all levels ‐‐ residents and fellows ‐‐ as well as practicing surgeons who wish to expand or solidify their knowledge in the field. … This is an extremely valuable and unique contribution. There is, currently, a plethora of books about hernia repair, but there is nothing like this book.” (Carol Scott‐Conner, Doody's Book Reviews, May 31, 2019)Table of ContentsSAGES University MASTERS PROGRAM: Hernia Pathway. Laparoscopic Ventral Hernia Repair.- Masters Program Hernia Pathway: Laparoscopic Inguinal Hernia.- Hernia Materials-Fundamentals of Prosthetic Characteristics.- Permanent Prosthetics: Polypropylene, Polyester, ePTFE, Hybrid Mesh.- Biologic and Absorbable Prosthetic: When, Why, and Where are we Going.- Prosthetic Fixation Options.- How to Choose a Mesh in Hernia Repair.- Patient Comorbidities Complicating a Hernia Repair: The Preoperative Workup and Postoperative Planning.- Enhanced Recovery in Abdominal Hernia Repair.- Computed Tomography and Gross Anatomy of the Abdominal Wall (Including Planes for Mesh Hernia Repair).- Umbilical Hernia Options.- Bridging Versus Closing the Defect during MIS Ventral Hernia Repair: Pros and Cons.- Robotic Technique for Intraperitoneal Onlay Mesh (IPOM).- Ventral, Incisional and Atypical Hernias Using a Robotic Transabdominal Preperitoneal Approach.- Technique: Posterior Rectus Sheath.- Ventral Abdominal Hernia Repair Technique: External Oblique Release.- Techniques: Transversus Abdominis Release.- Robotic Transveruss Abdominis Release: Tips and Tricks.- Ventral Abdominal Hernia Repair: MIS Extraperitoneal Repaie Techniques: eTEP Rives, MILOS/EMILOS and Onlay MIS Repair.- Component Separations: Outcomes and Complications.- Botulinum Toxin in Abdominal Wall Hernia Repair.- Mesh Sutured Repairs of the Abdominal Wall.- Treatment of Parastomal Hernias.- Challenging Hernias: Spigelian, Flank Hernias, Suprapubic, and Subxiphoid.- Recurrent Ventral Hernia Repair.- Loss of Abdominal Domain.- Fixation vs. Fixation in MIS Inguinal Hernia Repair.- Open Techniques: Mesh and Non-Mesh Anatomical Repairs.- MIS Techniques: Lap TAPP and rTAPP.- MIS vs Open Inguinal Hernia for Uncomplicated Unilateral Hernia.- TAPP vs. TEP vs. rTAPP: What does the Evidence Show?.- Minimally Invasive Surgical Techniques for Inguinal Hernia Repair: The Extended-View Totally Extraperitoneal Approach (eTEP).- Inguinal Hernia Repair with Mini-laparoscopic Instruments.- The Cavernous Direct Inguinal Hernia.- Remoral Hernia and Other Hidden Hernias: Options and Strategies.- Strangulated Inguinal Hernia: Options and Strategies.- Groin Pain Syndromes in Athletes: Sports Hernia.- Chronic Pain After Inguinal Repair.- Intraoperative and Postoperative Complications of MIS Inguinal Hernia Repair.- Repair of Paraesophageal Hernia.- Repair of Congenital Diaphragm Hernias: Morgagni and Bochdalek.- Revisional Paraesophaeal Hernia: Tips and Tricks.- Establishing a Hernia Program.- Prevention of Abdominal Wall Hernias.- Hernias in the Pediatric Population.- Herniorrhaphy in Cirrhosis: Operative Approach and Timing.- Concurrent Hernia Repair with Gynecologic or Urologic Surgery: Pros and Cons.

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Book SynopsisThis third edition text provides a completely revised and updated new version of this unique, modern, practical text that covers the strategic evaluation, specific approaches, and detailed management techniques utilized by expert colorectal surgeons caring for patients with complex problems–whether they result from underlying colorectal disease or from complications arising from previous surgical therapy. The format follows that of both a “how to” manual as well as an algorithm-based guide to allow the reader to understand the thought process behind the proposed treatment strategy. By making use of evidence-based recommendations, each chapter includes not only background information and diagnostic/therapeutic guidelines, but also provides a narrative by the author on his/her operative technical details and perioperative “tips and tricks” that they utilize in the management of these complex surgical challenges. Distinctive to this book, is the reliance on experts in the field including past presidents of the ASCRS, as well as multiple other national and internationally recognized surgeons, to lend their personal insight into situations where data may be more sparse, but individual and collective experience is paramount to making sound decisions and thereby optimizing patient outcomes. The text includes chapters on the assessment of risk and methods utilized to minimize perioperative complications. In addition, it incorporates sections covering the medical and surgical therapies for abdominal, pelvic and anorectal disease. Moreover, the technical challenges of managing complications resulting from the original or subsequent operations is addressed. The underlying focus throughout the text is on providing pragmatic and understandable solutions that can be readily implemented by surgeons of varying experience to successfully treat complex colorectal problems. However, it also goes beyond the technical aspects of colorectal surgery and includes special sections highlighting the essence of a surgeon; covering aspects involving the medical-legal, ethical, and economic challenges confronting surgeons. Throughout the text, each author provides an ongoing narrative of his/her individual surgical techniques along with illustrations and diagrams to “personally” take the reader through the crucial steps of the procedure, and key points of patient care inherent to that topic. Additionally, where appropriate, links to online videos give the reader an up-front look into technical aspects of colorectal surgery.Table of ContentsSECTION 1: PERIOPERATIVE/ ENDOSCOPY Chapter 1 Anatomy and Embryology of the Colon, Rectum & Anus Joseph C. Carmichael, MD and Steven Mills, MD Chapter 2 Colonic Physiology Joshua I. S. Bleier, MD, FACS, FASCRS and Kirsten Bass Wilkins, MD, FACS, FASCRS Chapter 3 Anal Physiology: The physiology of continence and defecation Vitaliy Poylin, MD, FACS, FASCRS and Thomas E. Cataldo, MD, FASC, FASCRS Chapter 4 Endoscopy Kurt Davis, MD and Michael A. Valente, DO, FACS, FASCRS Chapter 5 Endoscopic management of polyps, polypectomy and combined endoscopic and laparoscopic surgery Kelly A. Garrett, MD, FACS, FASCRS and Sang W. Lee, MD FACS FASCRS Chapter 6 Preoperative assessment of colorectal patients Jennifer S. Davids, MD and Justin A. Maykel, MD Chapter 7 Optimizing Outcomes with Enhanced Recovery Conor P. Delaney, MD, MCh, PhD, FRCSI, FACS, FASCRS and Raul Bosio, MD, MSBS Chapter 8 Postoperative Complications Andrew Russ, MD and Gregory D. Kennedy, MD, PhD Chapter 9 Anastomotic Construction Steven R. Hunt, MD and Matthew L. Silviera, MD Chapter 10 Anastomotic complications Konstantin Umanskiy MD, FACS, FASCRS and Neil Hyman MD, FACS, FASCRS SECTION II: ANORECTAL DISEASE Chapter 11 Approach to Anal Pain Amir L. Bastawrous, MD, MBA Chapter 12 Hemorrhoids Martin Luchtefeld, MD, FACS, FASCRS and Rebecca E. Hoedema, MS, MD, FACS, FASCRS Chapter 13 Anal Fissure Kim C. Lu, MD, FACS, FASCRS and Daniel O. Herzig, MD, FACS, FASCRS Chapter 14 Anorectal Abscess and Fistula Bradley R. Davis, MD, FACS, FASCRS and Kevin R. Kasten, MD Chapter 15 Complex Anorectal Fistulas Giulio A. Santoro, MD, PhD and Maher A. Abbas, MD, FACS, FASCRS Chapter 16 Rectovaginal Fistula Jamie A Cannon, MD Chapter 17 Pilonidal Disease and Hidradenitis Suppurativa Eric K. Johnson, MD, FACS, FASCRS Chapter 18 Dermatology and Pruritus Ani Wolfgang B. Gaertner, MSc, MD and Genevieve B. Melton, MD, PhD Chapter 19 Sexually Transmitted Infections Cindy Kin, MD and Mark Lane Welton, MD, MHCM Chapter 20 Anal Intraepithelial Neoplasia Rocco Ricciardi, MD, MPH SECTION III: MALIGNANT DISEASE Chapter 21 Anal Cancer Tushar Samdani, MD, MS, DNB(Surgery), MRCS(Edin) and Garrett M. Nash, MD, MPH Chapter 22 Presacral Tumors John Migaly, MD, FACS, FASCRS and Christopher R. Mantyh, MD Chapter 23 Molecular Basis of Colorectal Cancer and Overview of Inherited Colorectal Cancer Syndromes Matthew F. Kalady, MD and Y. Nancy You, MD, MHSc Chapter 24 Colorectal Neoplasms: Screening and Surveillance after Polypectomy Evie H. Carchman, MD and Charles P. Heise, MD, FACS, FASCRS Chapter 25 Colon Cancer: Preoperative Evaluation and Staging Cary B. Aarons, MD and Najjia N. Mahmoud, MD Chapter 26 The Surgical Management of Colon Cancer Matthew G. Mutch, MD, FASCRS, FACS Chapter 27 Rectal Cancer: Preoperative Evaluation and Staging Jorge Marcet, MD Chapter 28 Rectal Cancer: Neoadjuvant Therapy Andrea Cercek, MD and Julio Garcia-Aguilar, MD, PhD Chapter 29 Local excision of rectal neoplasia Mark H. Whiteford, MD, FACS, FASCRS Chapter 30 Rectal Cancer: Watch and Wait George J. Chang, MD, MS Chapter 31 Proctectomy Emmanouil P. Pappou MD, PhD and Martin R. Weiser MD Chapter 32 Rectal Cancer Decision Making W. Donald Buie MD MSc FRCSC FACS and Anthony R. MacLean MD FRCSC FACS Chapter 33 Colorectal Cancer: Postoperative Adjuvant Therapy Stephen M. Sentovich, MD, MBA and Marwan Fakih, MD Chapter 34 Colorectal Cancer: Surveillance after Curative-Intent Therapy Scott E. Regenbogen, MD, MPH and Karin M. Hardiman, MD, PhD Chapter 35 Colorectal Cancer: Management of Local Recurrence Eric J. Dozois, MD and Dorin T. Colibaseanu,MD Chapter 36 Colorectal Cancer: Management of Stage IV Disease Glenn T. Ault, MD, MSEd and Kyle G. Cologne, MD Chaptery 37 Appendiceal Neoplasms Constantine P. Spanos, MD FACS FASCRS and Andreas M. Kaiser, MD FACS FASCRS Chapter 38 Carcinoids, GISTs and Lymphomas of Colon and Rectum David J. Maron, MD, MBA SECTION IV: BENIGN COLORECTAL DISEASE Chapter 39 Diverticular Disease Jason Hall MD MPH FACS FACRS Chapter 40 Large Bowel Obstruction Karim Alavi, MD, MPH and Charles M Friel, MD Chapter 41 Lower Gastrointestinal Hemorrhage Brian R. Kann, MD, FACS, FASCRS and H. David Vargas, MD, FACS, FASCRS Chapter 42 Endometriosis Michael J. Snyder, MD, FACS Chapter 43 Trauma of the Colon, Rectum, and Anus W. Brian Perry, MD, FASCRS Chapter 44 Inflammatory Bowel Disease: Pathobiology Tara M. Connelly, MD, MB, BCh, MSc and Walter A. Koltun, MD, FACS and FACRS Chapter 45 IBD Diagnosis and Evaluation Matthew M. Philp, MD, FACS, FASCRS and Howard M. Ross, MD, FACS, FASCRS Chapter 46 Medical Management of Chronic Ulcerative Colitis Stefan D. Holubar MD, MS, FACS, FASCRS and Mattias Soop MD, PhD Chapter 47 Medical Management of Crohn’s Disease Scott A Strong, MD, FACS, FASCRS Chapter 48 Anorectal Crohn's disease Stephen R. Gorfine, MD Chapter 49 Crohn’s Disease: Surgical Management Roberta Muldoon, MD and Alan J. Herline MD Chapter 50 Ulcerative Colitis – Surgical Management Mukta K. Krane, MD, FACS, Erin O. Lange, MD, MSPH, and Alessandro Fichera, MD, FACS, FASCRS Chapter 51 Complications of the Ileal Pouch Daniel L. Feingold, MD and P. Ravi Kiran, P. Ravi Kiran, MBBS, MS (Gen Surgery), FRCS (Eng), FRCS (Glas), FACS, MSc (EBM) Oxford Chapter 52 Infectious Colitides Frederick R. Lane, MD and Dipen C. Maun MD Chapter 53 Clostridium difficile Infection David B. Stewart, Sr., MD, FACS, FASCRS Chapter 54 Radiation, microscopic, ischemic colitis Isabelle Raîche, MD, FRCS and Husein Moloo, MD MSc, FRCS Chapter 55 Intestinal Stomas Michael F. McGee, MD, FACS, FASCRS and Peter A. Cataldo, MD, FACS, FASCRS Chapter 56 Functional complications after colon and rectal surgery Dana M Hayden, MD, MPH and Alex Jenny Ky, MD SECTION V: PELVIC FLOOR DISORDERS Chapter 57 Common Tests for the Pelvic Floor Dana R. Sands, MD, FACS, FASCRS and Amy J. Thorsen, MD Chapter 58 Evaluation of Constipation and Treatment of Abdominal Constipation Muneera R Kapadia, MD, MME and Madhulika K Varma, MD Chapter 59 Obstructed Defecation M. Shane McNevin MD, FASCRS Rectal Prolapse Chapter 60 Brooke Gurland MD and Massarat Zutshi MD Chapter 61 Evaluation and Treatment of FI Ian M Paquette MD and Liliana Bordeianou MD Chapter 62 Functional Bowel Disorders for the Colorectal Surgeon Jennifer M. Ayscue, MD, FACS, FASCRS and Anjali S. Kumar, MD, MPH, FACS, FASCRS Chapter 63 Middle and Anterior Compartment: Issues for the Colorectal Surgeon Cecile A. Unger, MD, MPH and Marie Fidela R. Paraiso, MD SECTION IV: MISCELLANEOUS Chapter 64 Pediatric Colorectal Disorders Daniel H. Teitelbaum, MD, Peter F. Ehrlich, MD, MSc Chapter 65 Considerations for Geriatric Patients Undergoing Colorectal Surgery Kevin R. Kasten, MD and Todd D. Francone, MD, MPH Chapter 66 Guy R. Orangio, MD, FACS, FASCRS Health Care Economics Chapter 67 Ethical Issues in Colorectal Surgery Jason D. Keune, MD, MBA Chapter 68 Welcome to Litigation Dennis K. Ames, JD Chapter 69 Surgical Education Bradley J. Champagne, MD, FACS, FASCRS and Helen M. MacRae, MD, MA, FRCSC, FACS Chapter 70 Maintenance of Certification: Current Status and Future Considerations Jan Rakinic, M.D., FACS, FASCRS and W. Donald Buie, MD, MSc, FRCSC, FACS, FASCRS Chapter 71 Quality & Safety in Colon & Rectal Surgery Elizabeth C. Wick, MD and Jonathon Efron, MD Chapter 72 Practice Management Eric M Haas MD FACS FASCRS

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Book SynopsisThis volume is a state-of-the art resource on the recent advances and clinical management of NSAIDs and aspirin. The text provides a thorough overview of NSAIDS and aspirin, reviewing such topics as pharmacology and mechanisms, clinical effects, and the safety and efficacy of these drugs. It also focuses on the effect of the drugs on the cardiovascular system and in the prevention of GI cancer. Practical recommendations for a safe prescription of NSAIDs are also included. Written by experts in the field, NSAIDs and Aspirin: Recent Advances and Implications for Clinical Management is a comprehensive text of great value to gastroenterologists, rheumatologists, cardiologists, oncologists, orthopedists, trauma and internal medicine specialists. Trade Review“This well-organized book describes the pharmacology and effects on various organ systems of aspirin and NSAIDS, and guides clinical decision making regarding the use of these medications. … It is appropriate specifically for medical students interested in gastroenterology, but it can be used by those interested in other fields of medicine to better understand the significance of NSAIDs and aspirin. The author is very well versed in this area.” (Noah Settergren, Doody's Book Reviews, March, 2017)Table of ContentsSection 1. Pharmacology and MechanismsChapter 1. Chemistry, Pharmacodynamics, and Pharmacokinetics of NSAIDsSara Calatayud and Juan Vicente EspluguesChapter 2. Principles, Mechanisms of Action, and Future Prospects of Anti-Inflammatory DrugsBibiana Rius and Joan Clària Section 2. Clinical Effects and Drug SafetyChapter 3. Efficacy of NSAIDs in the Treatment of Rheumatic DiseasesMarc C. Hochberg and Lee S. SimonChapter 4. Adverse Effects of NSAIDs in the Gastrointestinal Tract: Risk Factors of Gastrointestinal Toxicity with NSAIDsSunny H. Wong and Francis K.L. ChanChapter 5. Adverse Effects of NSAIDs on the Cardiovascular SystemCarmelo Scarpignato and Corrado BlandizziChapter 6. Safe Prescription of NSAIDs in Clinical PracticeMohammad Yaghoobi and Richard H. HuntSection 3. AspirinChapter 7. NSAIDS and Aspirin: Recent Advances and Implications for Clinical ManagementKarsten Schrör and Michael VoelkerChapter 8. Non-Prescription Analgesic Anti-inflammatory Drugs: Efficacy and SafetyDenis M. McCarthyChapter 9. Low-Dose Aspirin in the Cardiovascular SystemRuben Casado-Arroyo, Angel Lanas, and Pedro BrugadaChapter 10. Adverse Effects of Low-Dose Aspirin in the Gastrointestinal TractKatsunori IijimaChapter 11. Aspirin in the Treatment and Prevention of Cardiovascular Disease: Need for Individual Clinical JudgmentsAngel Lanas and Charles H. HennekensSection 4. NSAIDS and Aspirin in Cancer PreventionChapter 12. Molecular and Experimental Basis for COX-Inhibition in CancerAnnalisa Bruno, Melania Dovizio, and Paola PatrignaniChapter 13. Clinical Effects of NSAIDs and Coxibs in Colon Cancer PreventionElena Piazuelo and Angel LanasChapter 14. Aspirin and the Prevention of Colorectal Cancer Paul J. Lochhead and Andrew T. ChanChapter 15. A Rational Approach for the Use of NSAIDs and/or Aspirin in Cancer Prevention in the Near Future: “Balancing Risk and Benefits”Elizabeth Half, Ahmad Fokra, and Nadir Arber

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Book SynopsisThe editors aim to provide the definitive guide for healthcare professionals on functional disorders of the gastrointestinal tract and pelvic floor, and the treatments used within the current healthcare context. This book will help the reader to access and understand relevant information within a variety of clinical settings and scenarios. It will be relevant and useful to a variety of disciplines (e.g. Physicians, Nurses, Physiotherapists) who work within the field of gastrointestinal care. This book will be written by a team from the worlds’ most well established colorectal specialist hospital, presenting a definitive guide to care of the patient group.Table of ContentsPart 1. Introduction.- 1. Background to bowel function and rationale for writing the book.- 2. Normal anatomy and physiology of bowel function with a view to including detail on the pelvic floor.- 3. Epidemiology Constipation and FI.- 4. Investigations: Anorectal Physiology.- Part 2. Causes and Assessment of Bowel Dysfunction.- 5. Causes of constipation/evacuatory dysfunction.- 6. The Assessment of Constipation and Evacuatory Disorders.- 7. Causes of faecal incontinence.- 8. The Assessment of Faecal Incontinence.- Part 3. Treatments for Bowel Dysfunction.- 9. Conservative management.- 10. Food choice as a Management Strategy in Bowel Dysfunction.- 11. Pharmacological therapy.- 12. Rectal Irrigation.- 13. Neuromodulation.- 14. Surgery .- 15. Psychological medicine for bowel dysfunction.

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Book SynopsisThis book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers’ understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special “clinical correlates” sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.Table of ContentsHistory of Development of Gastrointestinal Physiology: From Antiquity to Modern Period and the Birth of Modern Digestive Physiology.- Structural and Functional Organization of Gastrointestinal Tract.- Cellular Organization of the GI Tract.- Intercellular Network of the GI Tract.- Molecular Basis of Regulation of GI Functioning.- Gastrointestinal Growth and Development: From Zygote to Adulthood.- Gastrointestinal Motor Function.- Gastrointestinal Hormones.- Neural Secretions and Regulation of Gut Functions.- Gut Immunomodulatory Functions.- Gastrointestinal Exocrine (Lumencrine) Secretions. The Reception Theory as the Basis for Developing the First Antisecretory Pharmacotherapy Drugs.- Chemical Digestion, Absorption and Transport.- Metabolic Functions of the Gut.- Excretory Functions of the GI Tract. Defecation.- Physiology of Helicobacter pylori.- Functional Relationship between the Gut and Other Organs of the Body.- Gastrointestinal Functioning in Extreme Conditions of Temperature, Pressure and Gravity.- Appendix.

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