Gastrointestinal and colorectal surgery Books

Book SynopsisSince Mondors times in the forties of the last century there was no other book in surgery to be written so easy and witty Boris D. Savchuk, World Journal of Surgery This, the fifth edition of Scheins Common Sense Emergency Abdominal Surgery, builds on the reputation of the four previous editions. Already a worldwide benchmark, translated into half a dozen languages, this book guides surgeons logically through the minefields of assessment and management of acute surgical abdominal conditions. Tyro and experienced surgeons alike will benefit from the distilled wisdom contained in these pages. The direct, no-nonsense style gives clear guidance while at the same time providing amusing (or saddening) insights into our collective surgical psyche. Old chapters were revised or rewritten and new chapters have been added, including a completely new colorectal section with its new co-editor. Finally, in an attempt to rejuvenate the book, Danny took over the helm while the aging Moshe was pushed down the line Selected reviews and comments from readers of the previous edition What to say, perhaps the most appropriate medical book ever written. This is written with short punchy chapters making it a very difficult book to put down. By the end I was a total enthusiast this is a text like no other I read Unreservedly recommended to old and young alike. A Must Have Book. I am about to end my chief year in general surgery residency my copy of the first edition shows the wear of half a dozen total read throughs and probably hundreds of referencings... Simply perfect. The best choice in surgery for trainees! It makes the more difficult surgery areas very easy to understand. I recommend it to all surgeons. One of the best books I have read in my life! Must read for all docs out there. But the moral of the book is that if scientific rigorousness (protocols, guidelines, evidence-based) and common sense are at odds, follow common sense.

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Book SynopsisThe 28th edition of Bailey & Loveâs Short Practice of Surgery is the leading surgical resource for medical students and surgeons in training. It encompasses the basic principles of careful history taking, observation, deductive reasoning, technical knowledge and post-operative patient care to ensure safe surgical practice.Key features Relevant - the content matches both undergraduate and post-graduate curriculae Readable â features summary boxes of core knowledge throughout the text. The consistent layout and style of tables, graphics, and diagrams aids easy understanding of key concepts. Also includes algorithms to assist the reader in understanding patient care pathways Current- highlights where major developments in surgical practice have occurred or are likely to transform surgical practice in the next decade Contemporary â includes expanded coverage of paediatric surgery aTrade Review"The quality of content is in no doubt… this is likely to be the only general surgical book you will ever need." -Dr Harry Brown Table of ContentsPART ONE: BASIC PRINCIPLES . Metabolic response to injury. Shock, haemorrhage and transfusion. Wound healing and tissue repair. Tissue engineering and regenerative Therapies. Surgical infection. Tropical infections and infestations. Basic surgical skills. Diagnostic imaging. Gastrointestinal endoscopy. Principles of minimal access surgery. Principles of oncology. Surgical audit and research. Ethics and law in surgical practice. Human factors, patient safety and quality improvement. Global Health and surgery. PART TWO: GENERAL PAEDIATRICS. Paediatric surgery.Neonatal Surgery. Trauma in children. Paediatric Urology. PART THREE: PERIOPERATIVE CARE Pre-operative care including the high-risk patient. Day case surgery. Anaesthesia and pain relief. Post-operative care including perioperative optimisation.Nutrition and fluid therapy PART FOUR: TRAUMA Introduction to trauma. Early assessment and management of sever trauma. Traumatic brain injury. Torso and pelvic trauma. The neck and spine. Maxillofacial trauma. Extremity trauma. Disaster surgery. Conflict Surgery. PART FIVE: ELECTIVE ORTHOPAEDICS History taking and clinical examination in musculoskeletal disease. Sports medicine and sports injuries. The spine. The upper limb. The hip. The knee. The foot and ankle. Musculoskeletal tumours. Infection of the bones and joints. Paediatric orthopaedics PART SIX: SKIN, PLASTIC and RECONSTRUCTIVE Skin and subcutaneous tissue. Burns. Plastic and reconstructive surgery PART SEVEN: HEAD AND NECK Cranial Neurosurgery. The eye and orbit. Developmental abnormalities of the face mouth and jaws: cleft lip & palate. The ear, nose and sinuses. The pharynx, larynx and neck. Oral cavity cancer. Disorders of the salivary glands PART EIGHT: ENDOCRINE and BREAST. The thyroid gland. The parathyroid glands.The adrenal glands and other abdominal endocrine disorders. The breast. PART NINE: CARDIOTHORACIC Cardiac surgery. The thorax PART TEN: VASCULAR Arterial disorders. Venous disorders.Lymphatic Disorders. PART ELEVEN: ABDOMINAL History and examination of the abdomen. The abdominal wall, hernia and umbilicus. The peritoneum, mesentery, greater omentum and retroperitoneal space. The oesophagus. The stomach and duodenum. Bariatric and metabolic surgery. The liver. The spleen. The gall bladder and bile ducts. The pancreas. Functional disorders of the intestine. The small intestines. Inflammatory bowel disease. The vermiform appendix. The large intestine. Intestinal obstruction. The rectum. The anus and anal canal. PART TWELVE: GENITOURINARY Urinary symptoms and investigations. The kidney and ureter. The urinary bladder. The prostate and seminal vesicles. The urethra and penis. The testis and scrotum. Gynaecology. PART THIRTEEN: TRANSPLANTATION Kidney transplantation and the principles of transplantation. Liver transplantation. Pancreas transplantation. Intestinal and multivisceral transplantation.

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Book SynopsisThis, the 4th edition of Schein's Common Sense Emergency Abdominal Surgery, builds on the reputation of the three previous editions. Already a worldwide benchmark, translated into half a dozen languages, this book guides surgical trainees logically through the minefields of assessment and management of acute surgical abdominal conditions. General surgery as a concept may have been overtaken in many parts of the world by the development of niche specialties, but the need for a cohort of generalists able to deal competently with common surgical emergencies has not gone away. If you recognise this need then this is the book for you! Tyro surgeons and experienced practitioners alike will benefit from the distilled wisdom contained in these pages. The direct, no nonsense, writing style, supported by entertaining cartoons, gives clear guidance while at the same time providing amusing insights into our collective surgical psyche. NOT a standard textbook. Buy it! You will not regret it. Some new editors and authors enhance the new edition. Almost all chapters have been revised to take account of new concepts and modern developments. New chapters have been added and some completely rewritten often with a new emphasis on the importance of a laparoscopic approach.'Trade ReviewThis is written with short punchy chapters making it a very difficult book to put down." -- R A B Wood, Journal of the Royal College of Surgeons of Edinburgh"Since Mondors times in the forties of the last century there was no other book in surgery to be written so easy and witty..." -- Boris D Savchuk, World Journal of SurgeryBy the end I was a total enthusiast... this is a text like no other I read... Unreservedly recommended to old and young and alike." -- M Winslet, Royal Free Hospital, London, Colorectal Disease"The title describes this book perfectly. This is a no‐nonsense approach to the sometimes very difficult situations in general surgery. The authors describe their experiences in tough situations of patient care for residents and young attendings... the historical quotes add a good amount of insight and interest. I have not come across another book like this... Focused on the real situations that surgeons come across, the book answers the questions that are not addressed in the major textbooks." -- Robert A Hanfland, Doodys Review ServiceThis book covers emergency abdominal surgery in a useful and interesting way. [It is] a small and handy book yet the coverage is wide. It would be of interest to any general surgeon and should certainly be read by surgical trainees. [It] allows mention of many things which would otherwise be excluded from a more rigidly structured work. I was also glad to be reminded of many things which I had known but forgotten. The writers clearly know what they are talking about. -- David Evans, Annals of the Royal College of Surgeons of England

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Book Synopsis''THIS BOOK COULD SAVE YOUR LIFE'' Lorraine Kelly1 in 15 men. 1 in 18 women. Every year in the UK 43,000 people are newly diagnosed with bowel cancer. Dr Anisha Patel is one of them. Young, fit, and married to a consultant gastroenterologist and bowel cancer screening specialist, in 2018 she was diagnosed with Stage 3 bowel cancer. Despite being a family doctor, Anisha had no idea what would come next. With the benefit of hindsight, and after first-hand experience, she understands now that the diagnosis is just the beginning, that treatment can be physically and mentally overwhelming, and that the hard work really starts when the treatment ends. Drawing on her own experience and her medical expertise, as well as that of specialists in the field, Anisha''s book is an essential companion for anyone facing a cancer diagnosis. She outlines what to expect at each stage, from diagnosis, through treatment and into tTrade ReviewAnisha generously shares everything she has learned through her own bowel cancer journey to create this incredibly comprehensive one-stop-shop for anyone coping with cancer. Packed with practical tips and emotional support - from questions to ask your doctor to how to share the news with friends and family - this thoughtful book holds your hand throughout the journey of dealing with cancer and life afterwards. Her personality and expertise shines through this wonderful book, and we are very proud of her for sharing her experience so openly to help others. -- Genevieve Edwards, CEO, Bowel Cancer UKAnisha's experience as both a GP and a bowel cancer survivor gives her an important perspective on cancer and the impact of a diagnosis. She has a powerful voice to help others and is doing so much to raise awareness and support people going through treatment. -- Tom Bourton, Media Volunteer Liaison, Cancer Research UKI am so impressed by how Anisha has faced her personal challenges, while continuing to promote the awareness of bowel cancer from both a patient's and a doctor's perspective. This book is a great guide for anyone facing a cancer diagnosis, and Deborah would have been proud to know that it will help so many people. -- Heather JamesThis book is the best companion I have ever read for the journey following a cancer diagnosis... Told with care, compassion, humour, hope and honesty, it will help very many people. -- Adam KayEssentially reading for all of us, and brilliant advice. This book could save your life. -- Lorraine KellyA book that will no doubt help many people, a complete insider's guide to bowel cancer told with compassion, warmth and some very practical tips. A must-read for anyone going through, or who knows someone with, a bowel cancer diagnosis. -- Dr Amir KhanThis book is a must-read for anyone affected by bowel cancer. Dr Anisha shares her own story with humour and honesty and guides you through every single crazy thought that will come into your head whilst gently explaining everything that is happening. -- Dr Liz O'RiordanA brilliant, much needed book about all things related to bowel cancer. I have learnt so much, and its written in a very personable manner. -- Dr Nighat ArifThere is plenty of information to be found regarding bowel cancer, but when doctors themselves have experienced the condition, particularly when they are talented communicators, the information they impart is something truly special. Dr Anisha Patel writes with an authority, insight and passion which is truly unique. I would recommend this book to anybody who has ever been touched by bowel cancer. -- Dr Hilary Jones, GP, TV Presenter, Medical Broadcaster, Author and Public SpeakerA fantastic resource for anyone facing a bowel cancer diagnosis, their families and friends. -- Dr Zoe WilliamsAs a fellow cancer bowelie, I can tell you that Anisha truly 'gets it', and all that cancer entails. If you want to understand more, read this! -- Dr Philippa KayeThe word "everything" is not used lightly in the title of this book!... I believe everyone will learn something from it and also be able to find some hope, reassurance and camaraderie within its pages. -- Sam Alexandra Rose, Patient and Public Involvement (PPI) Manager, Bowel Research UK

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Book SynopsisTable of ContentsAnorectal investigation Colonoscopy and flexible sigmoidoscopy Colorectal cancer Colorectal cancer and genetics Surgery for colon cancer Surgery for rectal cancer Perioperative chemotherapy and radiotherapy for colorectal cancer Advanced and recurrent colorectal cancer Anal cancer Diverticular disease Ulcerative colitis Crohn's disease Intestinal failure Incontinence Functional problems and their surgical management Functional problems and their medical management Anal fistula: evaluation and management Minor anorectal conditions

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Book SynopsisTable of ContentsEvaluation of surgical evidence Perioperative care and enhanced recovery Organisation of emergency general surgical services Patient assessment and surgical risk Perioperative and intensive care management of the surgical patient Surgical nutrition Abdominal hernias Neck surgery for the general surgeon Human factors and patient safety in surgery Principles of organ donation and general surgery in the transplant patient Early assessment of the acute abdomen Perforation of the upper gastrointestinal tract Acute non-variceal upper gastrointestinal bleeding Pancreaticobiliary emergencies Acute conditions of the small bowel and appendix Colonic emergencies Anorectal emergencies Paediatric surgical emergencies Management of trauma for the general surgeon Abdominal sepsis and abdominal compartment syndrome Complications of bariatric surgery presenting to the general surgeon and considerations for the general surgeon when operating on the obese patient

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Book SynopsisAlmost all major liver diseases like viral hepatitis (A-E), non-alcoholic fatty liver diseases (NAFLD), and alcoholic liver diseases (ALD) are preventable, which highlights the significance and need for a book dedicated to a preventive approach to liver diseases. Covering all liver diseases, with a comprehensive focus on different levels of prevention (primordial, primary, secondary, and tertiary), with well-defined interventions provides an edge to this book. The contents specifically focus on key measures that can prevent the development of liver diseases or delay the progression and complication of chronic liver diseases, useful for medical students and clinicians. Key Features: 1. Focuses on understanding and practising preventive measures that help in lowering the risks of liver disease development, further preventing the need for specialised care, liver transplantation, and significantly reducing morbidity and mortality due to liver diseases. 2. Provides details on promotive,

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Book SynopsisThe management of injured and acutely unwell patients remains a cornerstone of surgical practice. Although techniques for assessment, investigation and operative management of the emergency surgical patient may be drawn from elective practice; they also require expediency of decision making and constant consideration of both anatomical and physiological pathology. Hamilton Baileyâs Emergency Surgery 14e is the famous textbook of emergency surgery that defines these key principles.Reflecting huge changes in the practice of emergency and general surgery over recent years, this new edition of Hamilton Bailey's Emergency Surgery is designed to meet the needs of basic and higher surgical trainees. The thorough and diverse coverage of emergency surgical principles including important anaesthetic and physiological considerations and the use of damage control techniques alongside core topics in emergency surgery such as shock and response to injury, surgical infections, principles of wound management and nutrition ensure that the clinician has evidence-based medicine to rely on. The extensive range of trauma surgery chapters cover all the surgical subspecialties as they relate to emergency surgery providing comprehensive coverage of acute care surgery.The new edition of this highly regarded textbook on emergency surgery provides the necessary knowledge and evidence base to help the on-call surgical trainee through the important decision-making process when treating acute surgical patients. In addition to guidance on relevant investigations and surgical techniques, emphasis is also placed on those non-technical skills including leadership and communication which are essential for the management of unwell patients.General surgeons and those working in the emergency setting will benefit from the gold standard expertise provided in the 14th edition of Hamilton Bailey's Emergency Surgery.

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Book SynopsisThis manual offers state-of-the-art diagnostic and therapeutic modalities drawn from Gastroenterology, Speech Language Pathology, Otolaryngology and Radiology, offering contributions of 28 innovators and master clinicians to benefit both patients and providers.Trade ReviewFrom the reviews:“This is a comprehensive overview of diagnostic and therapeutic interventions for dysphagia. … The book is written for healthcare providers who see patients with disorders of deglutition, which would include those in otolaryngology, gastroenterology, speech-language pathology, and rehabilitation medicine. … This is an important contribution to the field of dysphagia management, with detailed chapters on diagnostic and therapeutic options for patients. The chapters are well organized and easy to follow.” (Inna Athar Husain, Doody’s Review Service, November, 2012)Table of ContentsPart I: General Consideration in Evaluation of Dysphagic Patients 1. Establishing a comprehensive Center for diagnosis and therapy of swallowing disorders - Bronwyn Jones and William Ravich2. Clinical Evaluation of Patients with Dysphagia: Importance of History Taking and Physical Exam - Gary H. McCullough and Rosemary Martino Part II: Commonly Used Tests for Evaluation of Deglutitive Disorders3. Radiographic Evaluation of the Oral/preparatory and Pharyngeal Phases of swallowing including the UES: Comprehensive Modified Barium Swallow Studies - Jeri A. Logemann4. Radiographic Evaluation of the Esophageal Phase of swallowing - Marc Levine5. Flexible Endoscopic Evaluation of Swallowing (FEES) - Susan Langmore and Joseph T. Murray6. Laryngopharyngeal Sensory Testing - Jonathan Aviv7. Un-sedated Transnasal esophagoscopy: Endoscopic evaluation of esophageal phase of deglutition - Gregory Postma and Kia Saeian8. Manometry of the UES including High Resolution Manometry - Benson Massey9. Manometric Assessment of the Esophagus - Jeff Conklin10. Esophageal pH and impedance monitoring - Eytan Bardan11. Pharyngeal pH and impedance monitoring - Robert T. Kavitt and Michael F. Vaezi Part III: Management of Oral Pharyngeal Dysphagia in Adults12. Oropharyngeal Strengthening and Rehabilitation of Deglutitive Disorders - Jacqueline Hind and JoAnne Robbins13. Shaker Exercise - Caryn Easterling14. Mendelson Maneuver and Masako Maneuver - Cathy L. Lazarus 15. Effortful Swallow - Maggie Lee Huckabee and Phoebe Macrae16. Compensatory Strategies and Techniques - Susan Butler, Cathy Pelletier, Catriona M. Steele Part IV: Management of Oral Pharyngeal Dysphagia in Pediatrics17. Rehabilitative Maneuvers and Exercise - Joan Justine Sheppard18. Compensatory Strategies and Techniques - Claire Miller and Paul Willging19. Special Consideration in the Evaluation of Infants and Children with Deglutitive Disorders - Neelesh Tipnis

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Book SynopsisThis book provides a practical overview of the treatment and management of celiac disease. It examines new data which can be merged with clinical aspects to provide a global perspective for the busy clinician. The disease represents 1% of the population and often goes unnoticed for a long time; however, this book aims to reduce the instance of misdiagnoses of symptoms by providing clear guidance in a single book, with contributions from esteemed experts in the field. Advances in Celiac Disease - Improving Paediatric and Adult Care addresses the clinical characterisation of the disease, in both paediatric and adult populations. The clinical symptoms are clearly defined as well as treatment options and follow-up. This book will be an essential resource for clinicians seeking a clear, concise resource to identifying, treating, and managing celiac disease in both adults and children. Table of ContentsWhat is Celiac disease.- New Diagnostic Criteria for Children and Adolescents.- Classical Clinical Forms in childhood.- Extra-intestinal clinical forms in childhood.- Specific features of Celiac Disease in adults.- Epidemiology.- Importance of Histological Diagnosis.- Value of genetic markers.- Value of serological markers.- Autoimmunity and Celiac Disease.- Follow-up of pediatric patients.- Transition of the celiac patient: from the pediatrician to the adult gastroenterologist.- Follow-up of Adult patients.- Quality of Life and Celiac Disease.- New Research Fields in Celiac Disease.- Primary Health Care Prevention of Celiac Disease.- The Gluten-free Diet.- New therapeutic strategies.- Non celiac sensitivity to Gluten.

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Book SynopsisThis comprehensive manual discusses the many aspects of inflammatory bowel disease (IBD), providing relevant information along with practical guidance. The reader is also directed to additional resources for extra and current information. This book comes at a time when the number of people suffering from the two major forms of IBD, ulcerative colitis (UC) and Crohn’s disease (CD), is rising around the globe. Despite their huge impact on daily life and health economics, these diseases are not fully understood, and diagnosis and treatment remains a significant challenge. IBD nurses are increasingly recognised as key clinicians within the multidisciplinary team caring for people with IBD. Through experience and specialist knowledge IBD nurses provide timely support, advice, and treatment for people living with this unpredictable condition. IBD nurses are also well placed to liaise with the wider team, developing patient centred services which best fit their local health framework. The combined international expertise and accessible guidance here will equip nurses, or any clinician wanting to increase their competence in IBD management. Thereby this manual aims to contribute to the optimisation of IBD care throughout the world.Table of ContentsI.IBD Foundations: Anatomy and Physiology.- Epidemiology.- Aetiology, Pathophysiology and Localisation.- II. Diagnosis, Assessment and Monitoring: Clinical Assessment.- Endoscopy.- Lab.- Radiology.- Histopathology.- Monitoring.- Differential Diagnosis.-III.Managing IBD: Medical Management 1: General.- Medical Management 2: Conventional.- Medical Management 3: Biological.- New Therapeutic Treatments.- Antibiotics and Microflora (FMP).- Risks and Side-Effects of Medical Therapy.- Surgical Management.- Short Bowel Syndrome.- Alternative Therapies.- IV. Complications and Comorbidities: EIMs.- Penetrating CD and Fistulae.- Opportunistic Infections.- Cancer.- V. The Patient in... Newly Diagnosed Patient.- Fertility, Pregnancy and Lactation.- Young IBD.- Elderly.- Patient Priorities.- Dietary Management.- Stoma.- Pouch Care.- Adherence.- Constipation.- VI. Lifestyle Issues: Travel and Vaccination.- Smoking and Drugs.- Stress and Psychological Support.- Communication Skills.- Sport.- Sex and Intimacy.- Patient Support Groups.- VII. Research: Clinical Studies.- Nursing Research.- VIII. IBD Nursing: Training and Education.- E-health.- In Patient Care.- Nursing Support and IBD Networking.- Advice Lines.- Clinics.- Maintaining and IBD Nurse Service.- IBD Nurse Within the MDT.

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Book SynopsisBiopsy Pathology in Colorectal Disease shows how the practising pathologist can extract the maximum of diagnostic value from biopsies of the colon, rectum and anus. With the advances in colonoscopic mucosal biopsy techniques these are amongst the most frequently encountered specimens in hospital histopathology departments. This new edition provides practising pathologists and those in allied disciplines with a thorough guide to the diagnosis of colorectal conditions, both common and rare, and offers expert guidance in the handling of biopsy specimens. The most valuable information for diagnostic interpretation of the various types of inflammatory disease is presented clearly and succinctly, minimizing the use of non-diagnostic terms such as non-specific colitis. Optimal ways of handling and examining polyps, the assessment of biopsies in motility disorders and the interpretation of biopsies of anal lesions are described. A rational classification and practical approach to dysplasia is presented. The early chapters describe how to recognize the many different features, both normal and abnormal, which can be regarded as signposts to diagnosis. The significance of these diagnostic signposts is briefly described and cross referenced to later chapters, in which the histological features of the specific diseases are covered in greater depth.Trade Review"This book fulfils the needs of all clinicians and pathologists having to deal with various colorectal conditions, both common and rare, that are looking for an expert guidance for the diagnosis." Dr P Kitsanta, ACP News"This book is a must-keep and a worthy successor to the first edition ... One would hope that all surgical pathologists, whether practitioner or academic, residents or fellows, would read this superb publication." Gregory Y. Lauwers, Archives of Pathology and Laboratory MedicineTable of Contents1. Introduction2. Normal features3. Assessment of abnormalities: diagnostic signposts4. Infective colitis5. Ulcerative colitis6. Crohn's disease7. Ileoanal pouch pathology8. Pseudomembranous colitis9. Microscopic - colitis collagenous colitis, lymphocytic colitis and their variants10. Ischaemic colitis11. Iatrogenic disease12. The differential diagnosis of inflammatory bowel disease13. Disorders of motility14. Neoplasia in the colon and rectum and its classification15. Polyps16. The diagnosis of malignancy17. Dysplasia in inflammatory bowel disease18. Malignant tumours19. Anal biopsy20. Miscellaneous conditions

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Book SynopsisThere has been an exponential increase in the volume and quality of published research relating to colorectal disease over the last decades. This book identifies the 50 key scientific articles in the field of colorectal disease and colorectal surgery and through expert reflections and editorial perspectives explains why these papers are important. Influential contributors who have shaped the practice of modern Colorectal Surgery comment on the Landmark Papers that have shaped and defined the specialty.Among thousands of articles, a small fraction are truly âœgame changing.â Such studies form the foundations of colorectal surgery today and the selection of papers within this book provide the 50 landmark papers every 21st-century colorectal surgeon needs to know. A commentary to each carefully selected paper explains why these papers are so important, thus providing every surgeon with the foundation stones of knowledge in this fast-moving area.A valuable reference not only to the established surgeon, but also to colorectal surgery residents and trainees, as well as to more experienced surgeons as they continue to learn new techniques and approaches and to improve their knowledge of colorectal disease and treatments. The papers provide an evidence-based resource for those surgeons preparing for professional exams and may inspire clinicians to produce new research.

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Book Synopsis- This clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies - Includes AJCC staging of gastrointestinal malignancies - Each chapter ends with an up-to-date list of suggested readings and ''key practice points'' making it a usefuly at-a-glance reference - Text includes 80 illustrations Trade ReviewFrom the reviews: "This is the third volume of the MD Anderson Cancer Care Series, detailing their standard approach to care of patients with gastrointestinal cancer. It emphasises the day-to-day aspects of medical care, minimising both extensive literature review and approaches not yet incorporated into routine practice. It is a pleasant soft-backed volume of 394 pages with 61 diagrams and scans; there are also liberal tables. … a useful addition to every departmental library." (Dr. C. L. Harmer, RAD Magazine, November, 2005)Table of ContentsStaging of Gastrointestinal Malignancies.- Recent Advances in Histopathology of Gastrointestinal Cancers: Prognostic and Therapeutic Assessment of Colorectal Cancers.- Current Status of Imaging Techniques in Gastrointestinal Cancers.- Endoscopy in the Management of Gastrointestinal Malignancies.- Role of Laparoscopy in Gastrointestinal Malignancies.- Risk Factors for Colorectal Cancer Susceptibility.- Colorectal Cancer: Screening and Primary Prevention.- Hereditary Nonpolyposis Colorectal Cancer and Genetic Counseling.- Colon Cancer.- Rectal Cancer.- Metastatic Cancer of the Liver.- Staging and Therapeutic Approaches for Patients with Localized, Potentially Curable Pancreatic Adenocarcinoma.- Treatment of Primary Liver Cancer.- Gastric Cancer.- Esophageal Carcinoma.- Anal Cancer.- Gastrointestinal Stromal Tumors.- Palliative Therapy.- Bowel Management in Patients with Cancer.- Barrett’s Esophagus.

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Book SynopsisThe Royal College of Surgeons' of England two-day definitive surgical trauma skills course is run by the authors. The course began in 1997 but a new syllabus has recently been put in place.The focus is on thoracic ,abdominal and vascular injuries, caused by both penetrating trauma, such as a knife, and ballistic trauma caused by guns.This Manual accompanies the course and it''s aim is to demystify the body and show how to control massive blood loss. Interventions, whether they be military or civilian, are descrbed in full, and techniques derived from the battlefield and world-wide hotspots in trauma are exemplified within this book.Table of ContentsForewordPreface Editors Contributors1. The Philosophy of Damage Control Daniel Grabo, Patrick Reilly and C. William Schwab 2. Ballistics and Blast Injury David M. Nott, Mansoor Khan and Morgan McMonagle 3. Emergency Surgical Airway Morgan McMonagle 4. Thoracic Surgery James V. O’Connor 5. Vascular Trauma Morgan McMonagle 6. Fasciotomy of the Extremities Mark W. Bowyer 7. Damage Control for Severe Pelvic Haemorrhage in Trauma John H. Armstrong 8. Trauma Laparotomy and Damage Control Laparotomy David M. Nott 9. Abdominal Trauma Mansoor Khan 10. Future of Trauma Surgery: Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) Philip J. Wasicek, Thomas M. Scalea and Jonathan J. Morrison Index

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Book SynopsisThis open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, ultrasound, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. IDKD books are extensively re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their speciality. Table of ContentsEmergency radiology of the abdomen and pelvis (inkl. trauma).- Imaging infectious disease of the abdomen (including COVID).- Staging and monitoring of oncologic disease with emphasis on standardized reporting and hybrid imaging.- Benign and malignant diseases of the colon and rectum.- Retroperitoneal masses.- Diffuse liver disease.- Focal liver disease.- Diseases of the gall bladder and biliary tree.- Diseases of the pancreas.- Adrenal disease.- Benign and malignant renal disease.- Update on immunotherapies: the role of the radiologists in the era of precision medicine.- Benign disease of the uterus.- Malignant disease of the uterus.- Adnexal disease.- Prostate MRI.- Pathways for spread of disease in the abdomen.- Small bowel disease.- Congenital and acquired pathologies of the pediatric gastro-intestinal tract.- Congenital and acquired pathologies of the pediatric uro-genital tract.

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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Book SynopsisThis book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers’ understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special “clinical correlates” sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.Table of ContentsHistory of Development of Gastrointestinal Physiology: From Antiquity to Modern Period and the Birth of Modern Digestive Physiology.- Structural and Functional Organization of Gastrointestinal Tract.- Cellular Organization of the GI Tract.- Intercellular Network of the GI Tract.- Molecular Basis of Regulation of GI Functioning.- Gastrointestinal Growth and Development: From Zygote to Adulthood.- Gastrointestinal Motor Function.- Gastrointestinal Hormones.- Neural Secretions and Regulation of Gut Functions.- Gut Immunomodulatory Functions.- Gastrointestinal Exocrine (Lumencrine) Secretions. The Reception Theory as the Basis for Developing the First Antisecretory Pharmacotherapy Drugs.- Chemical Digestion, Absorption and Transport.- Metabolic Functions of the Gut.- Excretory Functions of the GI Tract. Defecation.- Physiology of Helicobacter pylori.- Functional Relationship between the Gut and Other Organs of the Body.- Gastrointestinal Functioning in Extreme Conditions of Temperature, Pressure and Gravity.- Appendix.

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Book Synopsis2. Stone extraction via the T-tube 89 3. Endoscopic method 89 4. Preparation for stone extraction 90 5. Technique 90 6. Results 91 7. Complications 91 8. Discussion 91 Index of Subjects 99 CHAPTER 1 INTRODUCTION This book was conceived as a descriptive atlas of most reliable indication for common bile duct ex­ routine biliary surgery i. e. , cholecystectomy and ploration. The cholangioscope allows a visual ex­ exploration of the common bile duct. For the pro­ ploration of the biliary tree and permits the re­ ject the two authors worked together for one week moval of common bile duct calculi and other as biopsy under direct visual con­ at Ninewells Hospital and Medical School, Dundee procedures such on a series of patients with biliary tract disease trol. Both procedures have been described in detail especially selected for the exercise. With the con­ with emphasis on the practical aspects of their use. sent of the Tayside Health Board and the patients The era of blind bilary surgery is over and the concerned, all the operations and peri-operative sooner this message is received by all concerned, procedures were filmed by the photographic mem­ the better the outcome of biliary surgical practice bers of the team, Mr. and Mrs. Paz-Partlow. Ad­ overall. ditional case material has been obtained from It has not been our intention to produce a com­ Cedars Sinai Medical Center, Los Angeles.Trade Review`...excellently illustrated... ...of value to all surgeons performing biliary tract surgery.' Gastrointestinal Endoscopy, 31:5 (1985) `...an easy to read and excellent cooperative project from Scotland and the USA between a surgeon, endoscopist and radiologist. It can be commended to abdominal surgeons and will make a useful contribution to safer cholecystectomy.' Journal of the Royal Society of Medicine, 78 (1985) `...should be of help to all surgeons in training.' British Medical Journal, 219 (1985) Table of Contents1. Introduction.- 2. Review of existing problems in biliary tract surgery.- 3. Surgical approach and principles.- 1. Introduction.- 2. Prophylactic measures.- 2.1. Infectious complications.- 2.2. Haemorrhagic complications.- 2.3. Renal failure.- 3. Pre-operative biliary decompression in the jaundiced patient.- 4. Operative principles.- 4.1. Surgical access.- 4.2. Patient positioning.- 4.3. Appropriate incision.- 4.4. Illumination of the operating field.- 4.5. Packing.- 4.6. Exposure of relevant anatomy.- 5. Drainage of the supracolic compartment after biliary operations.- 4. Operative cholangiography (in cooperation with J.A. Hamlin and M. Paz-Partlow).- 1. Introduction.- 2. Common bile duct explorations.- 3. Unsuspected stones.- 4. Cannulation techniques.- 5. Initial and/or completion cholangiograms.- 6. Standard technique.- 6.1. Technique and equipment.- 6.2. Patient’s positioning.- 6.3. Scout film.- 6.4. Injected volume.- 6.5. Contrast material.- 6.6. Coordination of exposure.- 6.7. Mobile C-arm fluoroscope.- 7. Fluoro-cholangiography.- 7.1. Easy positioning of the patient.- 7.2. Optimal beam collimation.- 7.3. Shorter exposure time.- 7.4. Automatic exposure control.- 7.5. Minimal technician activity.- 7.6. Control of the exposure sequence.- 7.7. Serial films.- 7.8. Decreased examination time.- 7.9. Indirect radiography.- 8. Anomalies of surgical importance.- 8.1. Short cystic duct.- 8.2. Drainage of cystic duct in the right hepatic duct.- 8.3. Aberrant ducts.- 8.4. Ductal diverticula and choledochocele.- 8.5. The acute or emergency case.- 9. General aspects.- 10. Radiation protection.- 11. The cystic duct.- 12. Cholecysto-cholangiogram.- 13. The choledocho-cholangiogram.- 13.1. Direct needle puncture.- 13.2. Butterfly needle puncture.- 13.3. Special needle clamp.- 13.4. T-tube insertion.- 14. Contact selective cholangiography.- 15. Reason for failure for operative cholangiography.- 15.1. Overfilled ducts.- 15.2. Underfilled ducts.- 15.3. Poor quality films.- 15.4. Improper positioning.- 15.5. Obscured field.- 16. Artifacts.- 17. Complications of operative cholangiography.- 18. Reformed calculi.- 19. Complications of T-tube removal in the post-operative period.- 20. Results of operative cholangiography.- 20.1. Advantages.- 20.2. Disadvantages.- 5. Operative biliary endoscopy (cholangioscopy) (in cooperation with M. Paz-Partlow).- 1. Introduction.- 2. Instrumentation.- 2.1. Accessories.- 3. Technique.- 3.1. Mobilization of the duodenum.- 3.2. Endoscopic appearance.- 3.3. The cystic stump remnant.- 4. Endoscopic anatomy and pathology.- 4.1. Normal findings.- 4.2. Cholangitis.- 4.3. Calculi.- 4.4. Ampullary stenosis.- 4.5. Neoplasms.- 4.6. Miscellaneous.- 5. Repeated cholangioscopy.- 6. Complications.- 7. General aspects.- 7.1. Sterilization.- 7.2. Maintenance.- 8. Evaluation of results.- 9. Conclusions.- 6. Biliary manometry and debimetry.- 1. Introduction.- 2. Usage.- 3. Pharmacolgy of the sphincter of Oddi (SO).- 3.1. Effect of hormones and peptides.- 3.2. Effect of pharmacological agents.- 4. Biliary pressure indices.- 4.1. Resting (initial, interdigestive) pressure.- 4.2. Passage (yield, opening) pressure.- 4.3. Filling pressure curves.- 4.4. Residual pressure.- 4.5. Flow rate (debimetry).- 4.6. Incremental pressure and recovery time.- 5. Dynamic (transducer) manometry.- 5.1. Endoscopic sphincter zone activity.- 5.2. Technique of operative biliary manometry.- 6. Disorders of the sphincter of Oddi.- 6.1. Iatrogenic stricture.- 6.2. Papillitis/Oedema.- 6.3. Papillary stenosis (choledocho-duodenal junctional stenosis).- 6.4. Functional disorders.- 7. Exploration of the common bile duct.- 1. Introduction.- 2. Technique of CBD exploration.- 2.1. Mobilization of duodenum and head of pancreas.- 2.2. Exposure of the CBD.- 2.3. Choledochotomy.- 2.4. Cholangioscopy.- 2.5. Additional procedures.- 2.6. Insertion of T-tube.- 2.7. Closure of choledochotomy wound.- 3. Trans-duodenal exploration od CBD.- 4. Intra-hepatic calculi.- 5. Assessment of terminal end of the CBD and sphincteric region.- 6. Post-operative removal of T-tube.- 7. Conclusion.- 8. Postoperative removal of retained stones through the T-Tube tract (in cooperation with J.A. Hamlin).- 1. Introduction.- 2. Stone extraction via the T-tube.- 3. Endoscopic method.- 4. Preparation for stone extraction.- 5. Technique.- 6. Results.- 7. Complications.- 8. Discussion.- Index of Subjects.

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Book SynopsisThe endoscopic use of lasers in the treatment of gastrointestinal d~seases began within the last decade and has evolved rapidly. Work is now being done at more than 150 centers in Europe, the United States, Japan and the rest of the world. To date no publi­ cation has defined the state of the art. This text attempts to fill that void. To disseminate information about therapeutic laser endoscopy, an increasing number of short courses have been sponsored in the United States wherein the attendee hears didactic lectures, views video tapes, and in addition, has the opportunity to have a "hands-on" experience with endoscopic laser therapy in the animal labs. This book is an expansion of the material presented in one such course sponsored by The Cook County Hospital in Chicago, Illinois, in October, 1982. The course was organized by Peter Bright-Asare, M. D. , Chairman of Gastroenterology at the time of the course and chaired by Dr. Bright-Asare and myself. Some of the lectures from the course have been broadened and formalized. Other chapters were invited and added. Also included are group discussions about issues that are either controversial or undefined. Attempts were made to secure consensus opinion from experienced investigators in areas where no hard scientific experimental or clinical data exists. The contributors have a wide range of interest and expertise. Dr.Table of Contents1. Medical laser fundamentals.- 2. Laser tissue interaction.- 3. Natural history of upper gastrointestinal bleeding and determinants of outcome.- 4. Endoscopic control of gastrointestinal bleeding with don-laser devices.- 5. Endoscopic and pharmacologic therapy of upper gastrointestinal bleeding. Laser vs. pharmacotherapy vs. autacid.- 6. European experience with Nd: YAG and argon laser for therapy of upper gastrointestinal bleeding.- 7. Controlled trials of laser therapy in the treatment of upper gastrointestinal haemorrhage.- 8a. Treatment techniques for massive upper gastrointestinal bleeding. General considerations.- 8b. Specific treatment techniques for massive upper gastrointestinal bleeding.- 9. Therapy of upper gastrointestinal bleeding: Electrocautery vs. argon laser vs. Nd: YAG laser. Panel discussion. Moderator.- 10. A general overview of treatment techniques. Panel discussion. Moderator.- 11. Endoscopic laser therapy of upper gastrointestinal carcinomas.- 12. Laser therapy of colonic neoplasms.- 13. Gastrointestinal angiomata: diagnosis and treatment with laser therapy and other endoscopic modalities.- 14. Non-gastrointestinal uses of lasers in medicine and surgery.- 15. Organization of a multidisciplinary laser center.- 16. Complications of endoscopic laser therapy.- 17. Use of lasers in community hospitals in United States.- 18. Legal aspects of laser use in the United States.- 19. Undecided issues about the use of lasers in gastrointestinal disease. Panel discussion. Moderator.- 20. Current limitations, new technological directions and areas of investigation. Panel discussion. Moderator.

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Book SynopsisDespite the fact that the incidence of gastric cancer is declining in the Western world, it remains a significant problem with respect to accurate diagnosis and treatment since it has a high mortality rate. In June 1989 an International Conference was held at the University of Rome "La Sapienza" entitled "New Trends in Gastric Cancer: Background and videosurgery". During this meeting background information on the aetiopathogenesis of gastric cancer was presented together with talks and video presentations on the latest advances in the treatment of gastric carcinoma, both from the European and Japanese experience. Because of the poor prognosis of gastric carcinoma there is increasing pressure for early detection. Some of the problems in the early detection of gastric carcinoma are discussed together with methods of surveillance of high-risk subjects. It is generally accepted that the surgical approach to gastric carcinoma should take into account the site and extent of the lesion and there are chapters on new methods for pre and intraoperative staging of the disease which allow a more logical approach to surgery. A comparison between Japanese and Western rule and results was attempted and reasons for the differences were investigated. Since the field is still evolving not all aspects could be covered, and those angles not approached in this book will be addressed in a second International Conference to be held in Rome in June 1990.Table of ContentsSection 1 Background.- 1 Epidemiology and machanism of gastric carcinogenesis.- 2 Histiogenesis and precursors of human gastric cancer.- 3 N-nitroso compounds, gastric carcinogenesis and chemoprevention.- 4 Analytical problems in the determination of N-nitroso compounds in gastric juice.- 5 Early detection of patients at high risk of developing gastric cancer.- 6 Prospects for early detection of gastric cancer and precancerous lesions.- Section 2 New Trends in Diagnosis.- 7 New trends in electronic videoendoscopy of the digestive tract.- 8 Endosonography: its diagnostic utilities for gastric cancer.- 9 Flow cytometry in gastric cancer.- Section 3 Surgical Treatment of Gastric Cancer.- 10 Intraoperative staging in gastric cancer surgery.- 11 New technologies in gastric cancer surgery: Computer system to make operation plan and intraoperative staining of regional lymph nodes for complete dissection.- 12 The general rule of the Japanese Research Society for Gastric Cancer and treatment results by the rule.- 13 A European multicentre retrospective study in cancer of stomach.- 14 Surgical treatment of gastric cancer: our elective procedures for desirable curability.- 15 “Regional” gastrectomy.- 16 Total gastrectomy in the surgical treatment of gastric cancer.- 17 The role of extensive surgery in advanced gastric cancer.- 18 The importance of extended lymphadenectomy in gastric cancer surgery.- 19 Duodenopancreatectomy for gastric cancer.- 20 Reconstruction after total gastectomy.

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Book SynopsisAntimicrobial-associated diarrhea is often caused by Clostridium difficile; this disease can best be diagnosed by detection of fecal cytotoxin in a tissue culture assay and, when therapy is indicated, can be effectively treated with orally administered vancomycin. The cause of disease in most cases of antimicrobial-associated diarrhea that do not involve C. difficile is not known; fortunately, this form of diarrhea 1S usually mild. Antimicrobial-associated diarrhea may also rarely involve s. aureus and certain enteric pathogens. 37 QHAPTER 4 Qf. TECTlON. ISOLATION Al:iQ...IQENTlFICATlON OF CLOSTRIDIUM PIFFICILE S. P. BORRIELLO and PAULINE HONOUR Introduction 38 Detection of Co dlfflcile in stools 38 Direct methods 38 Indirect methods 39 Isolation of Co djfficjle 40 Identification of Co difflcile 44 38 DETECTION ISOLATION AND IDENTIFICATION OF CLOSTRIDIUM DIFFICILE S. P. Borriello and Pauline Honour Introduction In view of the mounting evidence generated world wide in the last few years that firmly implicates GBP. difficile as the aetiological agent in both antibiotic and non-antibiotic associated pseudomembranous colitis (Larson ~ al. , 1978, Bartlett ~ al. , 1978a, George ~ al. , 1978a), and also recent recognition of the fact that there may be a spectrum of gastrointestinal diseases associated with GBP. difficile infections (Borriello and Larson, 1981, Bolton ~ al. , 1980, Brettle ~ al. , 1982), an increasing number of laboratories are seeking to detect, isolate and identify GBP. difficile from clinical samples.Table of Contents1 Antibiotics associated with Clostridium difficile mediated diarrhoea and/or colitis.- 2 Spectrum of disease.- 3 Diagnosis and treatment of antimicrobial agent-associated diarrhea and colitis.- 4 Detection, isolation and identification of Clostridium difficile.- 5 Detection of Clostridium difficile toxins.- 6 Epidemiology of antimicrobial agent-associated diarrhea and colitis.- 7 Typing Clostridium difficile.- 8 Clostridium difficile and colonization resistance.- 9 Characteristics of the toxins of Clostridium difficile.- 10 Interaction of Clostridium difficile toxin B (cytotoxin) with cultured cells.- 11 Animal models of Clostridium difficile infection.- 12 The pathology of antibiotic-associated colitis.- Concluding remarks The unanswered questions.- Reference section.

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Book SynopsisThe basis of this book is a ten-lecture course on the control of gastrointesti­ nal motility given each year to the final year undergraduate students in Physiology at Sheffield University. A naive thought led me to believe that the conversion of my lecture notes into the present book would be a relatively easy task. I now know differently. As there is no equivalent undergraduate course elsewhere that I know of, it would be dishonest of me to claim this book to be an undergraduate text. The comprehensive way in which I have dealt with the subject, together with the inclusion of the most up-to-date material, make the book more relevant to postgraduate students of physiology, medicine and related sciences who require an introduction to the field of gastrointestinal motility and its control. I have, however, attempted to present the current concepts on the physiological mechanisms regulating motility in a way which under­ graduates, as well as postgraduates, will find readable, informative and, hopefully, enjoyable.Table of Contents1 Gastrointestinal smooth muscle.- 2 Intramural ganglia and mechanisms of peristalsis.- 3 Extrinsic innervation.- 4 Neurocrines, endocrines and paracrines.- 5 The oesophagus.- 6 The stomach.- 7 The small intestine.- 8 The large intestine.- 9 The co-ordination of gastrointestinal motility: the fasted state.- 10 The co-ordination of gastrointestinal motility: the fed state.- References.- Further reading.

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Book SynopsisDDDDDDDDDDDDD Effective management logically follows accurate diagnosis. Such logic often is difficult to apply in practice. Absolute diagnostic accuracy may not be possible, particularly in the field of primary care, when management has to be on analysis of symptoms and on knowledge of the individual patient and family. This series follows that on Problems in Practice which was concerned more with diagnosis in the widest sense and this series deals more definitively with general care and specific treatment of symptoms and diseases. Good management must include knowledge of the nature, course and outcome of the conditions, as well as prominent clinical features and assess­ is on what to do best for the ment and investigations, but the emphasis patient. Family medical practitioners have particular difficulties and advantages in their work. Because they often work in professional isolation in the com­ munity and deal with relatively small numbers of near-normal patients their experience with the more serious and more rare conditions is restricted. They find it difficult to remain up-to-date with medical advances and even more difficult to decide on the suitability and application of new and rela­ tively untried methods compared with those that are 'old' and well proven. Their advantages are that because of long-term continuous care for their patients they have come to know them and their families well and are able to become familiar with the more common and less serious diseases of their communities.Table of Contents1. Gastro-oesophageal Reflux.- 2. Dysphagia.- 3. Nausea and Vomiting.- 4. Uncomplicated Peptic Ulcer.- 5. Complicated Peptic Ulcer.- 6. Surgical Management of Peptic Ulcer.- 7. Gastrointestinal Bleeding.- 8. Acute Abdominal Pain.- 9. Chronic Abdominal Pain.- 10. Acute Diarrhoea.- 11. Chronic Diarrhoea.- 12. Malabsorption.- 13. The Irritable Bowel Syndrome.- 14. Ulcerative Proctocolitis and Crohn’s Disease.- 15. Diverticular Disease of the Colon.- 16. Constipation and other Problems with Defaecation.- 17. Miscellaneous Gastrointestinal Problems.- 18. Jaundice and Common Liver Diseases.- Appendix: Patient Information Sheets and Diets.

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Table of Contents1 Studies on the interdigestive (migrating) motor complex in man.- 2 Migrating myoelectrical complexes in man.- 3 The interdigestive myoelectrical complex and other migrating electrical phenomena in the human small intestine.- 4 Effect of feeding and of gastrin on the interdigestive myoelectrical complex in man.- 5 Postoperative gastrointestinal complexes.- 6 The effect of different test meals on the interdigestive myoelectrical complex (MMC) in dogs.- 7 The effects of exogenous cholecystokinin and pentagastrin on myoelectrical activity in the small intestine of the conscious fasted dog.- 8 Longitudinal contractions in the jejunum of fasting dogs.- 9 Laxative effects on small intestinal electrical activity of the conscious dog.- 10 Migrating myoelectrical complexes: disruption, enhancement and disorganization.- 11 Treatment of diverticular disease with hydrophilic colloids.- 12 Control of motor activity in the lower oesophageal sphincter by motilin.- 13 The role of the cholinergie nervous system in the gastrointestinal response to motilin in vivo.- 14 VIP antagonizes motilin-induced antral contractions in vitro.- 15 Release of [3H]noradrenaline by electrical stimulation of human isolated taenia coli.- 16 2-2?-Pyridylisatogen antagonizes adenosine 5?-triphosphate but not nerve-mediated relaxations in human isolated taenia coli.- 17 Stimulatory actions of adenosine triphosphate in dog intestine.- 18 Effect of dopamine on gastric motility in man: evidence for specific receptors.- 19 Is dopamine an endogenous inhibitor of gastric emptying?.- 20 Low residue diet affects motility of the duodenum as well as the colon.- 21 Effects of 16,16-dimethyl prostaglandin E2 on the integrated response to a meal.- 22 Influence of nutritive density of a meal on gastric emptying in duodenal ulcer patients.- 23 The effect of vagotomy on gastric emptying of solid and liquid components of a meal.- 24 The effect of bran on colonic myoelectrical function in diverticular disease.- 25 Methods of analysing rhythmic electrical potentials in the gastrointestinal tract.- 26 Frequency analysis of electrical activity in dog colon.- 27 Gastroduodenal coordination: a computer analysis.- 28 Computer analysis of electrical and mechanical activity of stomach, duodenum and caecum over long periods.- 29 Real-time analysis of colonic myoelectrical rhythms in disease.- 30 Specific impedance of longitudinal and circular muscle from cat proximal jejunum.- 31 Colonic mechanoreceptor input to neurons in the coeliac plexus and superior mesenteric ganglion.- 32 Electrical activity of myenteric neurons: comparison of results obtained with intracellular and extracellular methods of recording.- 33 The genesis of the myoelectrical activity in the circular muscle layer from the cat colon: a pharmacological analysis.- 34 In vitro studies of the electrical activity of the longitudinal and circular muscle layers of the human colon.- 35 Human lower oesophageal sphincter (LES) response to submaximal and maximal effective doses of synthetic human big gastrin (G-34) and gastrin I (G-17).- 36 The effects of thyrocalcitonin on pentagastrin-induced contraction of the lower oesophageal sphincter in normals and in patients with achalasia.- 37 Comparison of the biological activity of pentagastrin, G-17 and G-34 on canine antral motility and intracellular electrical activity.- 38 Direct measurement of pyloric diameter and tone in man and their response to cholecystokinin.- 39 The relationship between gastric inhibitory peptide and right colon electromechanical activity after feeding.- 40 Colonic motility.- 41 Cellular ion concentrations and electrical control activity in various regions of the colon.- 42 Electrophysiological control of motility in canine colon.- 43 Nycthemeral variation of ileocolic myoelectrical activity in the cat.- 44 The identification of an electrically silent zone at the ileocaecocolic junction.- 45 Idiopathic intestinal pseudo-obstruction syndromes—A clinicopathological study of six adults.- 46 Activity of derivatives of tyrosine on gastrointestinal motility.- 47 Sources of inaccuracy in measurement of sphincter pressures using perfused catheters.- 48 Food sensitivity in reflux oesophagitis.- 49 Motor response of the human oesophagus to different intraluminal pHs.- 50 The role of the antral pacesetter potential in canine gastric emptying of solids.- 51 Myoelectrical activity and histology at duodenal anastomoses.- 52 Characterization of the feline pyloric sphincter by neural and hormonal stimulation.- 53 The pressure relationship in the gastric body, antrum and duodenum during gastric (abomasal) emptying in the calf.- 54 Transformation of the slow potential rhythm of the fundus of the stomach after functional loading following Billroth I gastrectomy.- 55 Vagal control of lower oesophageal sphincter function.- 56 The cat oesophagus: responses of the circular layer of smooth muscle from the body to electrical field stimulation.- 57 Mechanism of tetrodotoxin-insensitive relaxation of opossum lower oesophageal sphincter.- 58 Analysis of the electrical activity of the canine gastro-oesophageal sphincter in terms of overlapping pulse sequences.- 59 The myogenic control of oesophageal peristalsis and LES relaxation and interaction between myogenic and neural control systems.- 60 Comparison of mechanical characteristics of the lower oesophageal sphincter and pyloric sphincter.- 61 The role of the duodenum in the regulation of lower oesophageal sphincter pressure (LESP) in the dog.- 62 Clinical and experimental studies on the effect of nifedipine on smooth muscle of the oesophagus and LES.- 63 The upper oesophageal sphincter during vomiting, eructation and distension of the cardia: an electromyographic study in the unanaesthetized dog.- 64 Somatostatin inhibition of lower oesophageal sphincter pressure elevation caused by glycine: support for a role of endogenous gastrin in physiological responses of the sphincter.- 65 Sphincter of Oddi motor activity in man: a zone of unique, phasic high-pressure contractions.- 66 Antagonism by metoclopramide of some gastrointestinal effects of secretin.- 67 Effects of bile salts and prostaglandins on colonic motility in the rabbit.- 68 Evidence suggesting prostaglandins mediate lower oesophageal sphincter incompetence associated with inflammation.- 69 Hydrogen ions inhibit jejunal flow.- 70 Gastroduodenal contractile activity in fed and fasted unrestrained rats.- 71 Calibration of strain gauge force transducers and quantification of gastric motility.- 72 Pressure and motility studies in clinical practice.- 73 Relaxation oscillators.- 74 Human colonic modelling and multiple solutions in non-linear oscillators.

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Book SynopsisThis book offers essential information on basic and translational research in gastric cancer, while also illustrating potential opportunities for its application in clinical practice. Gastric cancer is the fourth-most-common cancer globally and the second-leading cause of cancer deaths. It is known to be a heterogeneous disease with varied responses to “one-size-fits-all” treatments. Expanding our knowledge of cancer cell genetics may help us to explore more effective treatments in gastric cancer. The research on molecular mechanisms and its clinical applications, both presented here, will help readers gain an in-depth understanding of gastric cancer and its effective treatment.The book’s four sections cover personalized medicine, precise regional therapy, immunotherapy and nanomedicine in gastric cancer. Each part presents the state of art, recent advances and the authors’ experiences. Moreover, several interesting cases are described to demonstrate how gastric cancer patients benefit from translational research. This informative and attractively presented book on precision treatment in gastric cancer, including experimental findings and clinical treatment options, offers a valuable resource for oncologists and graduate students working in the field of gastric cancer.Table of ContentsMolecular pathology of hereditary gastric cancer.- Genetics and molecular signature of gastric cancer.- Circulating tumor cells in gastric cancer.- Customized chemotherapy in advanced gastric cancer.- Targeted therapy in advanced gastric cancer.- Laparoscopic surgery and robotic surgery.- Radiotherapy in peritoneal metastatic gastric cancer.- Personalized intraperitoneal strategy in gastric cancer.- Checkpoint blockade therapy of gastric cancer.- Adoptive cell therapy of gastric cancer.- Combinational immunotherapy of gastric cancer.- Use of Nanomedicine in the diagnosis of gastric cancer.- Systemic drug delivery.- Local drug delivery.- Drug delivery in synergistic combination with other treatments.

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Book SynopsisWritten by an interdisciplinary team of experts, this book contains historical information as well as current update on renal replacement therapy. New technology and techniques are presented in a concise, easy-to-read style that keeps the reader interested.The contributors include physicians who practise uremia therapy since its conception to more recent graduates, along with surgeons, pioneers and physicians who are patients themselves, thus giving readers the broadest perspective.The aim of the book is to update the reader on renal replacement therapy as of 2009. It is a textbook that can be read cover to cover and still serve as a fine reference guide. The book is targeted at anyone interested in kidney replacement therapy, from students and patients to the professorial level.Table of ContentsContemporary Therapy circa 2009: Peritoneal Dialysis (M C Mallappallil); Hemodialysis (Y Woredekal); Hemofiltration (H Ghali); Home Hemodialysis (B G Delano); Self Care Hemodialysis (S H Bray); Kidney Transplantation (F Tedla); Opting for Death (A Joseph); Projected Therapy circa 2012: Bowel as Kidney (E A Friedman); Xenografted Kidneys (M O Salifu); Wearable Artificial Kidney (WAC) (V Gura).

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Book SynopsisUroradiology is an up-to-date, image-oriented reference in the style of a teaching file that has been designed specifically to be of value in clinical practice. All aspects of the imaging of urologic diseases are covered, and case studies illustrate the findings obtained with the relevant imaging modalities in both common and uncommon conditions. Most chapters focus on a particular clinical problem, but normal findings, congenital anomalies, and interventions are also discussed and illustrated.In this second edition, the range and quality of the illustrations have been enhanced, and many schematic drawings have been added to help readers memorize characteristic imaging findings through pattern recognition. The accompanying text is concise and informative. Besides serving as an outstanding aid to differential diagnosis, this book will provide a user-friendly review tool for certification or recertification in radiology.Table of ContentsNormal findings and variations of the urinary tract. Congenital anomalies of the upper urinary tract. Benign renal tumors. Malignant renal parenchymal tumors. Urothelial tumors of the pelvocalyces and ureter. Renal cysts and cystic diseases. Pediatric renal masses. Renal infection. Urogenital tuberculosis. Renal papillary necrosis. Renal parenchymal disease. Nephrocalcinosis. Urolithiasis. Obstructive uropathy. Vascular diseases of the kidney. Renal pelvis and ureter. Urinary bladder. Urethral diseases. Prostate. Imaging for seminal tracts. Scrotum. Varicocele. Erectile dysfunction and penile diseases. Retroperitoneal diseases. Adrenal gland. Renal trauma. Transplanted kidneys. Pediatric urinary tract infection and related conditions. Nonvascular interventions of the urinary tract. Renovascular interventions.

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Book SynopsisThis atlas provides a concise yet comprehensive overview of high-resolution manometry, impedance and pH monitoring. Through instructive text and over 130 high-yield images, the atlas describes the basic principles of esophageal, antroduodenal and anorectal high-resolution manometry, reviews both normal and pathologic findings on manometry, covers technical aspects of pH monitoring and impedance, and outlines advances in equipment, software, and diagnostic guidelines.Written by experts in the field, Atlas of High-Resolution Manometry, Impedance, and pH Monitoring is a valuable resource for gastroenterologists and other clinicians and practitioners who work or are interested in the GI motility field. Table of Contents1 Introduction to High-Resolution Manometry and Impedance 2 Esophageal Manometry3 Antroduodenal Manometry 4 Anorectal Manometry 5 Basic Principles of Ambulatory pH monitoring and Impedance

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Book SynopsisThis atlas provides a concise yet comprehensive overview of high-resolution manometry, impedance and pH monitoring. Through instructive text and over 130 high-yield images, the atlas describes the basic principles of esophageal, antroduodenal and anorectal high-resolution manometry, reviews both normal and pathologic findings on manometry, covers technical aspects of pH monitoring and impedance, and outlines advances in equipment, software, and diagnostic guidelines.Written by experts in the field, Atlas of High-Resolution Manometry, Impedance, and pH Monitoring is a valuable resource for gastroenterologists and other clinicians and practitioners who work or are interested in the GI motility field. Table of Contents1 Introduction to High-Resolution Manometry and Impedance 2 Esophageal Manometry3 Antroduodenal Manometry 4 Anorectal Manometry 5 Basic Principles of Ambulatory pH monitoring and Impedance

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Book SynopsisAcute appendicitis is one of the most common surgical abdominal emergencies worldwide, with a lifetime risk of 8.6% for males and 6.7% for females. This compilation discusses how while non-operative treatment of appendicitis has been proposed as an alternative to surgery, appendicectomy remains the mainstay of treatment in most cases and techniques have shifted from open to laparoscopic methods. The current knowledge in pathogenesis, diagnosis, and clinical management of acute appendicitis is also discussed. Next, the authors present an updated review chapter of appendicitis regarding its prevalence and risk factors, particularly how the diagnosis of appendicitis is based on a history of diffuse abdominal pain, which usually starts in the central region of the abdomen and migrates to the lower right quadrant of the abdomen. The residual remnant or "stump" of the appendix after an initial appendectomy may become inflamed causing what is commonly referred to as stump appendicitis. Treatment with antibiotics may be attempted as an alternative to surgery; however, the vast majority of cases require definitive surgical excision of the remnant appendix. The authors propose that keeping this disease in the differential is important in reducing complications associated with delayed diagnosis.

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Book SynopsisGastric cancer is the fourth most common cancer in the world. Most gastric cancers are diagnosed in advanced stages, and the prognosis remains poor. The 5-year survival rate is 40-60% in eastern countries and around 25% in the west. Among advanced gastric cancer cases, peritoneal implantation is one of the most common forms of metastasis and around 14% of cases present peritoneal metastases at initial diagnosis, presenting a survival of 3-6 months. Until the early 1990s it was considered a terminal disease. But today these patients have some opportunities to be treated with curative intent or to prolong their life. Although the prognosis remains poor, there are some treatment options including cytoreductive surgery, neoadjuvant therapy, and some forms of intraperitoneal chemotherapy with or without hyperthermia. These are aggressive treatments, so we must be careful when selecting patients. Imaging and preoperative staging are also crucial in selecting patients for appropriate treatment. The surgical technique is described and a detailed demonstration video is available in the e-book version. New forms of treatment such as PIPAC and new scientific advances and future perspectives are discussed. This book is an update on this topic and attempts to provide an overview for all medical personnel involved in the treatment of these patients.Table of ContentsPreface; Epidemiology of gastric cancer; Role of imaging in peritoneal surface malignancies; Diagnosis and staging in advanced gastric cancer; Histopathological and molecular classifications of gastric cancer; Patient selection and preoperative considerations; Neoadjuvant and adjuvant therapy; Principles of cytoreductive surgery; Role of intraperitoneal chemotherapy.; Current role of PIPAC in peritoneal metastases of gastric origin; Scientific Advances and future perspectives; Index.

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Book SynopsisObesity is a multifactorial global epidemic with associated risk factors for an array of vascular, metabolic, psychological and economical consequences. Bariatric surgery has revealed a significant link between gastrointestinal metabolism and obesity that extends to resolution of many metabolic diseases including type 2 diabetes and cardiovascular disease risk. Bariatric surgery offers the most effective results and Roux-en Y gastric bypass (RYGB) is the most commonly performed bariatric surgery worldwide. The effective weight loss achieved by RYGB is thought to be caused by the re-arrangement of the gastrointestinal tract leading malabsorption and restriction of the ingested nutrients, and consequently resulting in alterations in the gut hormone levels. The first chapter of this book briefly summarises the current literature on the changes in the gastrointestinal hormones following RYGB. Chapter Two studies the role of bariatric surgery in the resolution of obesity and type 2 diabetes. Chapter Three discusses how to treat a type 2 diabetes patient post-bariatric surgery. The last chapter discusses the recent findings of the relationship between gastric bypass and four different skin disorders.

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Book SynopsisThis book is a topical review of issues the editors consider to be 'hot topics' and will be of interest to qualified consultant colorectal surgeons and those performing general surgery with an interest in colorectal surgery. In addition, the topics picked are likely to be ones that candidates taking the Intercollegiate Examination in General Surgery will be quizzed upon. It is not intended to be a textbook covering all aspects of colorectal surgery. Rather, it is meant to be an up-to-date view of current and probable near future advances. Frontiers in neoplasia, inflammatory bowel disease, anal disorders and management are covered by acknowledged experts, known to be active in the field. The implications of deep pelvic dissection and pouch surgery in males and females are sensitively explored. Each chapter contains three main sections entitled 'What is the problem/issue?', 'Where are we now?' and 'Where are we going?'. Referencing for the first two is key and current; the last section is speculative with the occasional reference. This volume should find a place on the coloproctologist's bookshelf as an exciting review of contemporary themes, complementing traditional textbooks.

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