Clinical and internal medicine Books

Book SynopsisTable of ContentsPreface vii Contributors ix 1 Why Inclusion Matters 1 Shehla Imtiaz-Umer and John Frain 2 The Impact of Bias in Healthcare 11 Habib Naqvi 3 Racism in Healthcare 17 Olivia King and Anton Emmanuel 4 Ethnicity and Disease 27 Mohammad Rizwan Ali, Shehla Imtiaz-Umer, and John Frain 5 Representation in Healthcare Training 37 Diana Akpeki, Zunaira Dara, and John Frain 6 Women in Healthcare 45 Olivia O’Connell and Anna Frain 7 Sexual Orientation and Gender Identity 53 Duncan McGregor 8 Disability Disparities and Ableism in Medicine 61 Lisa I. Iezzoni 9 Migrants and Displaced People 69 James Smith 10 Mental Health 75 Oluwaseun Oluwaranti 11 Privilege, Power and Intersectionality in Healthcare 83 Shehla Imtiaz-Umer 12 Allyship and Being an ‘Active Bystander’ 93 Diana Lautenberger 13 Teaching Equality, Diversity and Inclusion in Healthcare 101 Sylk Sotto-Santiago Index 109

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Book SynopsisTable of ContentsContributors xviii Preface xxv Acknowledgements xxvii Chapter 1 Advanced Clinical Practice 1 Sadie Diamond-Fox and Vikki-Jo Scott Learning Outcomes 1 Introduction 1 The Concept and History of Advanced-Level Practice 3 Frameworks and Toolkits for Advanced Clinical Practice 3 Ensuring Quality and Governance in Advanced Practice 3 How to Use this Book 5 Conclusion 5 References 7 Further Reading 8 Self-Assessment Questions 8 Glossary 8 Chapter 2 The Advanced Clinical Practice Curriculum 10 Rachael Daw and Ollie Phipps Learning Outcomes 10 Introduction 10 Curriculum Development 12 Understanding the Context of ACP 14 The Clinical Practice Curriculum 14 The Leadership and Management Curriculum 15 The Education Curriculum 15 The Research Curriculum 16 Assessment for ACP 16 Specialist Curriculums, Credentials and Capability Frameworks 18 First Contact Practitioners and Advanced Practitioners – Roadmaps to Practice 19 Supervision and CPD Strategies 19 Conclusion 21 References 22 Further Reading 23 Self-Assessment Questions 24 Glossary 24 Chapter 3 Scope of Practice and Management of Patient Care 25Ollie Phipps Learning Outcomes 25 Introduction 25 The Multi-Professional Framework (MPFFACP) 26 Governance 27 Legal Issues 27 Regulation Statements of Standards and Code of Conducts 28 Nursing and Midwifery Council (NMC) 28 Health and Care Professions Council (HCPC) 28 General Pharmaceutical Council (GPhC) 28 Scope and Capability 28 Defining Scope of Practice 28 Competency vs Capability 29 Knowledge, Skills and Behaviours 29 Competence 29 Multiprofessional Registrations and Scope of Practice 30 Expanding Scope and Scope Creep 30 Responsibility and Accountability 30 Dunning–Kruger Effect 31 Imposter Syndrome 31 Professional Issues 31 Indemnity 33 Indemnity Insurance 33 Negligence 34 Duty of Care 34 Breach of Duty 34 Causation 34 Mental Health Act 1983 and Sections 35 Mental Capacity Act 36 Ethics 37 Autonomy 37 Non-maleficence 38 Beneficence 38 Justice 38 The Right to Life and the Right to Dignity 38 Consent 39 Gillick Competence 39 Confidentiality 39 Development and Regulation 39 Conclusion 40 References 40 Further Reading 42 Self-Assessment Questions 42 Glossary 43 Chapter 4 Principles of Physiology for Advanced Practice 44 Colin Chandler, Alison Wood, and Robin Hyde Learning Outcomes 44 Introduction 45 How the Body Adapts to Different Situations 47 Key Concepts of the Cell 52 Contents vii Control – How the Body Allows us to Achieve Action and Participation in Society 55 Changes to Physiology Through the Life Course 57 Microbiome/Microbiota and Interactions with the Microbiological Environment 61 Conclusion 62 References 63 Further Reading 64 Self-Assessment Questions 64 Glossary 64 Chapter 5 Principles of Pathophysiology 66 Sarah Ashelford and Vanessa Taylor Learning Outcomes 66 Introduction 67 The Main Disease Mechanisms 68 Cancer 69 Aetiology and Pathogenesis of Cancer 70 Clinical Investigations 72 Learning Events 72 Clinical Effects of Cancer 72 Learning Event 72 Cardiovascular Disease and Stroke 73 Investigations 73 Pathogenesis of Atherosclerosis 73 Pharmacological Principles 76 Investigations 76 Diabetes 76 Clinical Presentation 76 Learning Event 77 Aetiology and Pathogenesis of Type 1 Diabetes 77 Aetiology and Pathogenesis of Type 2 Diabetes 78 Acute Complications of Diabetes 79 Respiratory Disease 81 Asthma 81 Aetiology and Pathogenesis of Asthma 81 Pharmacological Principles 83 Learning event 83 Chronic Obstructive Pulmonary Disease 83 Aetiology and Pathogenesis of COPD 83 Conclusion 86 References 86 Further Reading 89 Self-Assessment Questions 89 Glossary 89 Chapter 6 Principles of Pharmacology 90 Ihab Ali and Phil Broadhurst Learning Outcomes 90 Introduction 90 Pharmacotherapy 91 Pharmacokinetics (PK) 91 VIII Contents Pharmacodynamics (pd) 93 Pharmacodynamics: Drug–Receptor Interactions 94 Pharmacodynamics: Drug Concentration 94 Therapeutic Drug Monitoring (TDM) 96 Plasma Protein Binding 98 Drug-induced Adverse Effects 100 Drug Interactions 103 Contraindications 103 Excipients 104 Adherence 104 Conclusion 107 References 107 Further Reading 111 Self-Assessment Questions 111 Glossary 111 Chapter 7 Supplementary and Independent Prescribing 113 Brigitta Fazzini, Esther Clift, and Jill Bentley Learning Outcomes 113 Introduction 113 Education 115 General Pharmacological Principles 115 Prescribing in Paediatrics 115 Prescribing in Mental Health 116 Prescribing in Critical Care 117 Absorption 117 Distribution 117 Metabolism 118 Excretion 119 Assessing Drug Therapy in Critical Illness 119 Prescribing in Older People 120 Medication Reviews 120 Pharmacokinetics 121 Guidelines on Drug Prescription for Older People 122 Antibiotics Stewardship 123 Authorisation of Blood Components and Products 125 Legal Aspects and Governance 125 Patient Consent 126 Clinical Decision Making 126 De-Prescribing 127 Health Promotion 127 Why is This Important to Us as Prescribers? 128 So What Can We Do? 128 Social Prescribing 129 Conclusion 130 References 130 Further Reading 131 Self-Assessment Questions 131 Glossary 131 Chapter 8 Core Procedural Skills 132 Mark Cannan, Kirstin Geer, and Stuart Cox Learning Outcomes 132 Introduction 132 Consent/Assent 133 Clinical Competence for Procedures 134 Preparation: Positioning 135 Core Procedural Skills 137 Airway: Basic Manoeuvres and Adjuncts 137 Airway: Supraglottic Airway Devices 137 Breathing: Intercostal Drain Insertion 137 Preprocedure Set-up and Equipment for ICD Insertion 137 Procedure for ICD Insertion (Seldinger) – Small Bore 139 Procedure for ICD Insertion – Large Bore (Lloyd 2019) 141 Postprocedure Checks 141 Pearls and Pitfalls 141 Circulation: Venepuncture 142 Practitioner Safety 142 Technique 143 Postprocedure Checks 144 Pearls and Pitfalls 144 Circulation: Peripheral Intravenous Cannulation 144 Technique 145 Postprocedure Checks 146 Pearls and Pitfalls 146 Circulation: Arterial Puncture and Cannulation 147 Technique 148 Postprocedure Checks 149 Pearls and Pitfalls 149 Circulation: Central Venous Access Via Central Venous Catheter 149 Technique 150 Pearls and Pitfalls 151 Circulation: Intraosseous Needle Insertion 152 Preprocedure Considerations 152 Pearls and Pitfalls 152 Disability: Lumbar Puncture 153 Technique 154 Pearls and Pitfalls 155 Exposure: Nasogastric Tube Insertion 156 Technique – Awake Patient 156 Technique - Unconscious/Anaesthetised/Intubated Patient 157 Postprocedure Checks 157 Pearls and Pitfalls 157 Learning From Patient Safety Events 158 Conclusion 158 References 159 Further Reading 161 Self-Assessment Questions 161 Glossary 161 Chapter 9 Clinical History Taking and Physical Examination 162 Sadie Diamond-Fox, Rebecca Connolly, Alexandra Gatehouse, and John Wilkinson Learning Outcomes 162 Introduction 162 The Consultation as a Diagnostic Tool 163 Communication 164 The Cone Technique 164 Ideas, Concerns and Expectations (ICE) 165 Triggers to Consultation 165 Consultation Models 165 Calgary-Cambridge Guide to the Medical Interview 167 Patient Perspective of Consultation 168 Kinesics Interviewing 168 Aspects of Obtaining a Medical History 169 History Taking in Special Circumstances: Time-Critical Situations 171 History Taking for Neurodiverse and Non-verbal Populations 172 History Taking for Ethnic Minority Populations 173 History Taking for LGBTQIA+ Populations 173 Clinical Assessment – Aspects of Physical Examination 175 Introduction 175 General Inspection 176 Vital Signs 176 Physical Examination Techniques 177 Hands and Nails 177 Upper Limbs 181 Head and Neck 181 Thorax 185 Abdomen 188 Lower Limbs 190 Closing the Consultation 190 Conclusion 191 References 191 Further Reading 194 Self-Assessment Questions 194 Glossary 194 Chapter 10 Clinical Decision Making and Diagnostic Reasoning 195 Helen Francis-Wenger and Colin Roberts Learning Outcomes 195 Introduction 195 Clinical Reasoning and Clinical Decision Making 197 Recognition 200 Probability 200 Reasoning 200 Watching and Waiting 200 Selective Doubting 201 Iteration and Reiteration 201 Thinking, Growing and Evolving 201 Contents xi Decision-Making Theories 203 Normative, Prescriptive and Descriptive Interactions 203 Descriptive Approach 203 Normative Approach 203 Prescriptive Approach 204 Intuition 204 Hypothetico-Deductive Reasoning 205 Cue Acquisition Stage 205 Hypothesis Generation 205 Cue Interpretation 206 Hypothesis Evaluation 206 The Cognitive Process 206 Biases 207 Assistive Tools and Concepts: Risk Assessments/Probability Scores/Risk Stratification 210 Odds Ratios 210 Numbers Needed to Treat 210 Bayes’ Theorem: Sensitive (Rule Out) and Specific (Rule In) 210 Risk Stratification 211 Conclusion 211 References 211 Further Reading 213 Self-Assessment Questions 213 Glossary 213 Chapter 11 Diagnostic Interpretation 214 Colin Roberts, Christine Eade, and Helen Francis-Wenger Learning Outcomes 214 Introduction 214 Principles to Follow 216 Principles of Ordering and Interpretation 216 Reference Ranges 217 Patient and Clinician Factors to Consider When Interpreting Results: Context 217 The Full Blood Count 217 Haemoglobin 217 A Stepwise Approach 218 White Cells (Leucocytes) 219 Platelets (Thrombocytes) 219 Raised Platelets (>400) 219 Low Platelets (<150) 219 Inflammatory Markers 220 C-Reactive Protein 220 Plasma Viscosity 220 Renal Function 220 Range 220 Creatinine (Cr) 221 Urea (U) 221 Acute Kidney Injury 221 Chronic Kidney Injury 221 Electrolytes: Sodium and Potassium 221 Electrolytes: Calcium and Magnesium 223 Liver Function Tests 225 Alanine Aminotransferase (ALT) 225 Alkaline Phosphatase (ALP) 225 Bilirubin (Br) 225 Patterns of Liver Disease 225 Thyroid Function Tests 226 Hypothyroidism (Underfunctioning) 226 Hyperthyroidism (Overfunctioning) 226 Subclinical Hypothyroidism and Hyperthyroidism 227 Diagnostic Interpretation: Imaging 228 Fundamental Principles 228 The Essentials of Each Imaging Modality are Considered Below 229 Plain Film 229 Ultrasound 232 Lung Ultrasound 232 FAST Scan 233 Echo 233 Computed Tomography 233 Imaging Summary 234 References 235 Further Reading 236 Self-Assessment Questions 236 Glossary 236 Chapter 12 Public Health: Prevention, Promotion and Empowerment 238 Joanna Lavery and Sharon Riverol Learning Outcomes 238 Introduction 238 Accreditation Considerations 240 Clinical Examination 242 Leg assessment 244 Clinical investigation – point-of care (POC) D-dimer testing 244 Diagnosis – Class 1 Cellulitis 245 Pharmacology 245 Follow-up Plan 246 Clinical Examination 248 Results 249 Management 249 Pharmacology 249 Clinical Examination 251 NEWS2 – 0 But Blood Pressure Found to Be Hypotensive 251 Neuro assessment 251 Management 253 Reflections 255 Admission Avoidance 255 Advanced Care Practitioner and Patient Empowerment 255 References 256 Further Reading 261 Self-Assessment Questions 261 Glossary 262 Chapter 13 Managing Complexity 263 Jaclyn Proctor and Sadie Diamond-Fox Learning Outcomes 263 Introductions 263 Medical Complexity 265 Measuring Complexity in a Healthcare Context 266 Situational Complexity 269 Systems Complexity 270 NHS Long Term Plan (2019) 270 Advanced Clinical Practice 272 Conclusion 275 References 276 Further Reading 277 Self-Assessment Questions 277 Glossary 277 Chapter 14 Frailty: Principles of Rehabilitation and Reablement, Palliative Care and Organ Donation 278 Esther Clift and Stevie Park Learning Outcomes 278 Introduction 278 Discharge Planning 279 Intermediate Care 280 Rehabilitation 281 Reablement 282 Pathways 282 Technology 282 Home-based Care 282 Virtual Wards 283 Urgent Community Response 283 Palliative or End-of-Life Care 284 Gold Standard Framework 285 Care Plans 285 Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) 286 Pain and Symptom Control 286 Verifying Death 287 Organ Donation 287 Diagnosing Death by Neurological Criteria (Brainstem Death Testing) 287 Role of the SN-OD and Referral Process 288 Tissue Donation 288 Clinical Frailty 288 Diagnosis Tools for Diagnosis and CGA 288 Exercise 290 Nutrition 290 Social Isolation and Loneliness 291 Conclusion 293 References 293 Further Reading 295 Self-Assessment Questions 295 Chapter 15 Mental Health, Learning Disability and Autism 296 Clare Allabyrne and Jo Delrée Learning Outcomes 296 Introduction 297 Parity of Esteem 297 Diagnostic Overshadowing and Unconscious Bias 297 Mental Health and Ethnicity 298 Communication 298 Therapeutic Communication 298 Fundamental Principles of Therapeutic Communication 298 Specific Issues in Communication Clients with ASD/LD 299 Clinical Investigations 299 Mental Health Screening Tools 299 Holistic Mental Health Assessment 299 Ten-point Guide to Mental State Examination 301 Risk Assessment in Mental Health 301 Assessing Different Groups 302 Assessing Children and Young People 302 Assessing People with Autism 303 Assessing People with Learning Disability 304 A Note on Challenging Behaviour 307 Pharmacological Principles 307 Resources 309 Learning Disability Learning Event 309 Mental Health Learning Event 309 Mental Health UK states 309 Conclusion 310 References 310 Further Reading 313 Self-Assessment Questions 313 Glossary 313 Chapter 16 Education and Learning 315 Joe Wood and Elizabeth Midwinter Learning Outcomes 315 Introduction 316 Principles of Teaching and Learning 316 Understanding How We Learn 316 Recognising Adult Learners 317 Dual Coding Theory 317 Evidence-based Practice 318 Contents xv Self-directed Learning 318 Supporting Others to Develop Knowledge and Skills 318 Feedback 318 Appraisal Processes and Continuing Professional Development 319 Learning From Mistakes: Safety I and Safety II 319 Coaching, Mentoring and Role Modelling 319 Creating an Effective Learning Environment 320 Optimise the Space 320 Physial 320 Virtual 321 Ensure Learner-centredness 321 Get to Know the Learner 322 Plan the Process 322 Create Psychological Safety 323 Promote Continual Improvement Via Reflection 324 Simulation and Technological Advances in Healthcare Education 324 Simulation 324 Teaching Practical Skills – Reflections from Clinical Experience 325 Human Factors 325 Interprofessional Education 326 Types of Simulation 327 The Concept of Fidelity 328 In Situ Simulation 329 Designing Simulated Learning 329 Scenario Writing 330 Practical Considerations 330 Introductions and Orientation 330 Pre-brief 330 Programmed vs On the Fly 331 Debrief 331 Technology-enhanced Learning 333 Conclusion 334 References 334 Further Reading 338 Self-Assessment Questions 338 Glossary 338 Chapter 17 The Advanced Practitioner as Educator 339 Phil Broadhurst Learning Outcomes 339 Introduction 339 Providing Feedback 342 Feeding Back and Feeding Forward 343 The One-Minute Preceptor 345 Conclusion 347 References 347 Further Reading 349 Self-Assessment Questions 350 Glossary 350 Chapter 18 Research Principles 351 Brigitta Fazzini and Roberta Borg Learning Outcomes 351 Why Research Is Important 351 The Research Process 352 Critical Appraisal and the Hierarchy of Evidence 353 Designing a Research Project 354 Every Research Project Starts with a Question 354 Research Methods 355 Scientific Hypothesis 355 Quantitative versus Qualitative Research Methods 356 Quantitative Research Method 357 Qualitative Research Method 359 Healthcare Research Ethics 360 Quality Improvement 362 Conclusion 364 References 364 Further Reading 365 Self-Assessment Questions 366 Glossary 366 Chapter 19 Leading Research in Advanced Practice 367 Leanne Dolman, Joanna De Souza, and Sara Stevenson-Baker Learning Outcomes 368 Introduction 368 Enabling Evidence-Based Practice 369 Using Local Procedures and Protocols – Role Modelling and Ensuring Continuity of Practice 370 Auditing Current Practice 370 Utilising Clinical Audit 371 Setting Standards and Developing New Protocols 371 Setting Intended Outcomes 371 Patient-reported Outcome Measures 372 Reviewing your Protocol (Quality Control) 372 Developing Guidelines at a National/International Level 373 Developing New Evidence for Practice 373 Leading on Quality Improvement 374 Dissemination of Existing and New Knowledge 377 Local Dissemination 377 Presenting at an External Conference 377 Developing a Conference Abstract 378 Developing a Poster 378 Developing an Oral Presentation 378 Writing for Publication 378 Joining a National Forum or Guideline Development Group 378 Developing the Advanced Practitioner as a Clinical Academic 379 Creating A Research Culture at Organisational Level to Improve Person-Centred Healthcare 380 Conclusion 381 References 382 Further Reading 384 Self-Assessment Questions 384 Glossary 384 Chapter 20 Innovations in Practice 386 Vanessa Taylor and Sarah Ashelford Learning Outcomes 386 Introduction 386 Innovation, Practice Development and Service Improvement 388 Innovation and Advanced-level Practice and the Advanced Practitioner Role 392 Advanced-level Practice and Workforce Transformation: An Example of Healthcare Service Innovation 392 Advanced Practitioner as Clinical (Practice Development/ Improvement) and Professional (Service/System Development) Innovator 394 Conclusion 400 References 401 Self-Assessment Questions 403 Glossary 403 Chapter 21 Professional Development and Transition 404 Vikki-Jo Scott and Esther Clift Learning Outcomes 404 Introduction 405 Personal Professional Development 405 Continuing Professional Development and Role Transition 410 Supporting Professional Development Within a Team 412 Contribution to Broader Development of Advanced Practice 415 What Next? 416 Conclusion 416 References 417 Further Reading 417 Self-Assessment Questions 418 Glossary 418 Index 419

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Book SynopsisA full-color guide to the entire field of clinical endocrinology and its scientific underpinnings â updated with the latest breakthroughs and developmentsA Doodyâs Core Title for 2022! Greenspanâs Basic & Clinical Endocrinology delivers a succinct, leading-edge overview of the underlying molecular biology of the endocrine system and the latest perspectives on the diagnosis and treatment of specific diseases and disorders. Featuring an enhanced design that includes hundreds of full-color illustrations and clinical photographs, Greenspanâs is a true must-have during traditional or integrated courses in endocrinology, endocrinology rotation, or exam prep in internal medicine and endocrinology and as reference for disease management.Greenspanâs provides clinically relevant coverage of metabolic bone disease, pancreatic hormones and diabetes mellitus, hypoglycemia, obesity, geriatric endoc

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Book SynopsisHematology Timely morphology resource based on ongoing series of morphology updates published in the American Journal of Hematology since 2008 This is the first book of its kind, written by renowned author Professor Barbara J. Bain, featuring a collection of instructive cases with interesting morphological features initially published in the American Journal of Hematology. This new book aims to bring these interesting and instructive cases to a wider readership. This book features updated cases and a Test Yourself section to aid in reader comprehension and information retention. Cases covered in Hematology: 101 Morphology Updates include: The significance of irregularly contracted cells and hemighosts in sickle cell disease, and striking dyserythropoiesis in sickle cell anemia following an aplastic crisis Prominent Howell-Jolly bodies when megaloblastic anemia develops in a hyposplenic patient, and unusual aspects of G6PD Table of ContentsPreface x Note to the reader xi Acknowledgements xii Abbreviations xv 1 Malaria – one swallow makes a summer 1 2 The significance of irregularly contracted cells and hemighosts in sickle cell disease 2 3 Striking dyserythropoiesis in sickle cell anemia following an aplastic crisis 3 4 A normal mean cell volume does not exclude a diagnosis of megaloblastic anemia 4 5 Prominent Howell–Jolly bodies when megaloblastic anemia develops in a hyposplenic patient 6 6 A ghostly presence – G6PD deficiency 7 7 G6PD deficiency in patients identified as female 8 8 The cause of sudden anemia revealed by the blood film 9 9 Choreo-acanthocytosis 10 10 Lead poisoning 12 11 Dysplastic neutrophils in an HIV-positive woman 14 12 Help with HELLP 15 13 Neutrophil dysplasia induced by granulocyte colony-stimulating factor 16 14 COVID-19 and acute kidney injury 17 15 Diagnosis of pyrimidine 5′nucleotidase deficiency suspected from a blood film 19 16 Bone marrow aspirate in Chédiak–Higashi syndrome 20 17 Phytosterolemia 21 18 Pseudo-Chédiak–Higashi inclusions together with Auer rods in acute myeloid leukemia 22 19 Botryoid nuclei resulting from cocaine abuse 23 20 Infantile pyknocytosis 25 21 Splenic rupture in cytomegalovirus infection 27 22 A new diagnosis of monoclonal B-cell lymphocytosis with cytoplasmic inclusions in a patient with COVID-19 29 23 Pseudoplatelets and apoptosis in Burkitt lymphoma 31 24 What is a promonocyte? 32 25 Persistent neonatal jaundice resulting from hereditary pyropoikilocytosis 34 26 Auer rods or McCrae rods? 36 27 Observation of Auer rods in crushed cells in acute promyelocytic leukemia 37 28 Alpha chain inclusions in peripheral blood erythroblasts and erythrocytes 39 29 Dyserythropoiesis in visceral leishmaniasis 41 30 Compound heterozygosity for hemoglobins S and D 42 31 Granular B lymphoblastic leukemia 43 32 Hyposplenism in adult T-cell leukemia/lymphoma 44 33 Voxelotor in sickle cell disease 45 34 The importance of a negative image 48 35 Seeing what isn’t there 49 36 A young woman with sudden onset of a severe coagulation abnormality 50 37 Immature Plasmodium falciparum gametocytes in bone marrow 51 38 Acute myeloid leukemia with myelodysplasia-related changes showing basophilic differentiation 52 39 Thiamine-responsive megaloblastic anemia in an Iraqi girl 53 40 Teardrop poikilocytes in metastatic carcinoma of the breast 54 41 A blood film that could have averted a splenectomy 55 42 Russell bodies and Mott cells 57 43 Dutcher bodies 59 44 Acute myeloid leukemia with inv(16)(p13.1q22) 61 45 Dysplastic macropolycytes in myelodysplasia-related acute myeloid leukemia 63 46 Diagnosis of cystinosis from a bone marrow aspirate 64 47 Emperipolesis in a patient receiving romiplostim 65 48 Mechanical hemolysis: a low mean cell volume does not always represent microcytosis 66 49 Transplant-associated thrombotic microangiopathy 67 50 Neuroblastoma in the bone marrow 69 51 Gray platelet syndrome 70 52 Diagnosis of systemic lupus erythematosus from a bone marrow aspirate 71 53 Diagnosis from a blood film following a dog bite 72 54 Interpreting a postpartum Kleihauer test 73 55 Dengue fever in returning travellers 74 56 Auer rod-like inclusions in multiple myeloma 76 57 Azurophilic granules in myeloma cells 77 58 Plasmodium knowlesi 78 59 The cytological features of NPM1-mutated acute myeloid leukemia 79 60 Irregularly contracted cells in Wilson disease 81 61 Pseudo-Pelger–Huët neutrophil morphology due to sodium valproate toxicity 82 62 The distinctive cytological features of T-cell prolymphocytic leukemia 83 63 Eosinophil morphology in the reactive eosinophilia of Hodgkin lymphoma 86 64 Malaria pigment 87 65 Salmonella colonies in a bone marrow film 88 66 Severe babesiosis due to Babesia divergens acquired in the UK 89 67 Congenital acute megakaryoblastic leukemia 91 68 Basophilic differentiation in transient abnormal myelopoiesis 92 69 Methylene blue-induced Heinz body hemolytic anemia in a premature neonate 93 70 Neutrophil vacuolation in acetominophen-induced acute liver failure 95 71 Howell–Jolly bodies in acute hemolytic anemia 96 72 The distinctive micromegakaryocytes of transformed chronic myeloid leukemia 97 73 Copper deficiency 98 74 Chronic neutrophilic leukemia 99 75 Neutrophilic leukemoid reaction in multiple myeloma 101 76 Persistent polyclonal B lymphocytosis 103 77 Non-hemopoietic cells in the blood and bone marrow 104 78 It’s a black day – metastatic melanoma in the bone marrow 105 79 Dehydrated hereditary stomatocytosis 106 80 Circulating lymphoma cells in intravascular large B-cell lymphoma 107 81 Unusual inclusions in hemoglobin H disease post-splenectomy 108 82 An unexpectedly bizarre blood film in hemoglobin H disease 109 83 Acute myeloid leukemia with a severe coagulopathy and t(8;16)(p11;p13) 111 84 Cold autoimmune hemolytic anemia secondary to atypical pneumonia 113 85 A confusing ‘white cell count’ – circulating micromegakaryocytes in post-thrombocythemia myelofibrosis 114 86 Diagnosis of follicular lymphoma from the peripheral blood 115 87 Transformation of follicular lymphoma 117 88 Cytology of systemic mastocytosis 118 89 Systemic mastocytosis – the importance of looking within bone marrow fragments 119 90 Schistocytosis is not always microangiopathic hemolytic anemia 120 91 Hemoglobin C disease 121 92 Hemoglobin St Mary’s 122 93 Congenital sideroblastic anemia in a female 123 94 A puzzling case of methemoglobinemia 125 95 Hodgkin lymphoma in a bone marrow aspirate 127 96 Giant proerythroblasts in pure red cell aplasia due to parvovirus B19 infection in a patient with rheumatoid arthritis 128 97 A myeloid neoplasm with FIP1L1::PDGFRA presenting as acute myeloid leukemia 129 98 Breast implant-associated anaplastic large cell lymphoma 131 99 Large granular lymphocytosis induced by dasatinib 132 100 The distinctive cytology and disease evolution of blastic plasmacytoid dendritic cell neoplasm 134 101 Platelet phagocytosis as a cause of pseudothrombocytopenia 136 Test yourself 137 Answers to test cases 145 Index 152

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Book SynopsisA practitioner guide summarizing the aims and achievements of evidence-based healthcare and why it is crucial to modern clinical practice ABC of Evidence-Based Healthcare explains how evidence is developed and formulated into guidance for clinicians. It details how to interpret and apply this evidence to one's own practice and patients, covering areas such as diagnosis and screening, therapy, harm, and prognosis. Some of the key aspects discussed in this book include understanding choice of study design, the roles of quantitative and qualitative research, selecting and using appraisal tools and key statistical concepts. Additionally, the book also covers how to interpret the results of research studies, apply results to the needs of patients, communicate results to colleagues and incorporate them into student training, as well as discussing treatment options, risks, and benefits with patients. As in all ABC books, the text is complemented with practical examples of evidence in practic

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Book SynopsisThe latest edition of an essential resource for nursing and healthcare students covering the anatomy and physiology of children and young people Fundamentals of Children and Young People's Anatomy and Physiology, 3rd Edition contains the critical knowledge associated with anatomy and physiology required to provide safe and effective care to children and young people. Emphasising the application of evidence-based theory to practice, this comprehensive yet accessible textbook helps nursing and healthcare students understand how children's anatomical and physiological systems influence disease processes and treatment options differently than in adults. This third edition includes an expanded focus on ethnic minority communities and representation of gender and LGBTQI+ issues to ensure a more inclusive understanding of diversity in the population. Readers will also find: A collection of effective pedagogical tools designed to enhance learning, including chapter-specific learning objectives

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Book SynopsisA concise, illustrated, and accessible guide to the nervous system Each of the twelve volumes in Peate's Body Systems series is rooted in the belief that a deep and thorough understanding of the human body is essential for providing the highest standard of care. Offering clear, accessible and up-to-date information on different body systems, this series bridges the gap between complex scientific concepts and practical, everyday applications in health and care settings. This series makes for an invaluable resource for those committed to understanding the intricacies of human biology, physiology and the various systems that sustain life. The Nervous System is the perfect companion for students and newly registered practitioners across nursing and allied health fields with an interest in neurological care, providing a comprehensive yet easy-to-digest guide for both academic and clinical application. Equips healthcare students and practitioners with the necessary information to provide saf

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Book SynopsisA concise, illustrated, and accessible guide to the skin Each of the twelve volumes in Peate's Body Systems series is rooted in the belief that a deep and thorough understanding of the human body is essential for providing the highest standard of care. Offering clear, accessible and up-to-date information on different body systems, this series bridges the gap between complex scientific concepts and practical, everyday applications in health and care settings. This series makes for an invaluable resource for those committed to understanding the intricacies of human biology, physiology and the various systems that sustain life. The Skin is the perfect companion for students and newly registered practitioners across nursing and allied health fields with an interest in dermatological care, providing a comprehensive yet easy-to-digest guide for both academic and clinical application. Equips healthcare students and practitioners with the necessary information to provide safe and competent ca

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Book SynopsisA concise, illustrated, and accessible guide to the ear, nose and throat Each of the twelve volumes in Peate''s Body Systems series is rooted in the belief that a deep and thorough understanding of the human body is essential for providing the highest standard of care. Offering clear, accessible and up-to-date information on different body systems, this series bridges the gap between complex scientific concepts and practical, everyday applications in health and care settings. This series makes for an invaluable resource for those committed to understanding the intricacies of human biology, physiology and the various systems that sustain life. Ear, Nose and Throat is the perfect companion for students and newly registered practitioners across nursing and allied health fields with an interest in Ear, Nose and Throat (ENT) care, providing a comprehensive yet easy-to-digest guide for both academic and clinical application. Equips healthcare students a

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Book SynopsisAdopted at Cambridge University Essential Medical Genetics provides students, clinicians, counsellors and scientists with the up-to-date information they need regarding the basic principles underlying medical genetics. It also provides guidance on how to apply current knowledge in clinical contexts, covering a wide variety of topics: from genome structure and function to mutations, screening and risk assessment for inherited disorders. This sixth edition has been substantially updated to include, for instance, the latest information on the Human Genome Project as well as several new molecular genetic and chromosome analysis techniques.In full colour throughout, it includes a number of brand new features, including: a large number of self-assessment questions; ''Essentials'' chapter summaries; further reading suggestions; and case study scenarios introducing clinical situations. An invaluable new section gives illustrated practical advice regarding Trade Review“Essential Medical Genetics is the perfect resource for a course on medical genetics, and is now accompanied by a regularly updated website and the FREE enhanced Wiley Desktop Edition (upon purchase of the book) .” (MedReport, 9 October 2012) “I have watched this textbook from its first inception and was disappointed that there was no new edition for so many years. Having waited, the result now is excellent and it has overcome my preference for Emery's Elements as a basic human genetics text.” Emeritus Professor in Clinical Genetics "I find the reference to electronic resources particularly useful, especially for people who approach clinical genetics for the first time and are not familiar with these tools." Dr Sixto García-Miñaúr, Imperial College London, and Hospital Universitario La Paz, Madrid, Spain Reviews of the previous edition "This book is an easy to read, well illustrated introduction to medical genetics. It deals nicely with all the classical aspects of the subject..." Black Bag, Medical Students' Society of Bristol University "...a justifiably popular introductory text." The British Medical JournalTable of ContentsPreface vii Acknowledgements ix How to get the best out of your textbook x Part 1: Basic principles 1 1 Medical genetics in perspective 3 Scientific basis of medical genetics 5 Clinical applications of medical genetics 9 2 The human genome 13 Structure and organisation of the genome 14 Gene identification 14 Th e Human Genome Project 14 3 Nucleic acid structure and function 23 Nucleic acid structure 24 Nucleic acid function 26 Gene regulation 29 DNA replication 31 Mutation types, eff ects and nomenclature 32 4 DNA analysis 41 Basic methods 42 Mutation detection 43 Indirect mutant gene tracking 52 Analysis of DNA length polymorphisms 53 Analysis of single-nucleotide polymorphisms 54 5 Chromosomes 57 Chromosome structure 58 Chromosome analysis 59 Chromosome heteromorphisms 65 Chromosomes in other species 66 Mitochondrial chromosomes 68 Mitosis 69 6 Gametogenesis 73 Meiosis 74 Spermatogenesis 76 Oogenesis 78 Fertilisation 78 X-inactivation and dosage compensation 79 Sex chromosome aberrations 80 Sex determination and differentiation 83 Genomic imprinting (parental imprinting) 83 7 Chromosome aberrations 89 Numerical aberrations 90 Structural aberrations 92 Cytogenetic and molecular methods for the detection of chromosomal aberrations 100 Identification of the chromosomal origin of complex structural rearrangements 107 Other aberrations 111 8 Typical Mendelian inheritance 117 Introduction to autosomal single-gene inheritance 118 Autosomal dominant inheritance 118 Autosomal recessive inheritance 120 Introduction to sex-linked inheritance 123 X-linked recessive inheritance 125 X-linked dominant inheritance 127 Y-linked inheritance (holandric inheritance) 128 9 Atypical Mendelian inheritance 131 Genetic anticipation 132 Pseudoautosomal inheritance 134 Autosomal dominant inheritance with sex limitation 134 Pseudodominant inheritance 134 X-linked dominant inheritance with male lethality 135 Mosaicism 135 Modifi er genes and digenic inheritance 135 Uniparental disomy 136 Imprinting disorders 136 10 Non-Mendelian inheritance 141 Multifactorial disorders 142 Somatic cell genetic disorders 147 Mitochondrial disorders 147 11 Medical genetics in populations 151 Selection for single-gene disorders 152 Founder effect and genetic drift for single-gene disorders 153 Altered mutation rate for single-gene disorders 154 Linkage analysis and the International Hapmap Project 154 Human population evolution and migration 155 Part 2: Clinical applications 161 12 Genetic assessment, genetic counselling and reproductive options 163 Communication of advice 164 Special points in counselling 168 Prenatal diagnosis 170 Amniocentesis 170 Chorionic villus sampling 174 Cordocentesis, fetal skin biopsy and fetal liver biopsy 175 Ultrasonography 175 Fetal cells in the maternal circulation 175 Free fetal DNA and RNA detection 175 Preimplantation genetic diagnosis 176 13 Family history of cancer 179 General principles 180 Tumour suppressor genes 181 Genes involved in DNA repair mechanisms 187 Oncogenes 187 Other cancer-related genes 189 Genetic counselling aspects of cancer 189 Common familial cancer predisposition syndromes 189 14 Family history of common adult-onset disorder 199 General principles 200 Diabetes mellitus: common and monogenic forms 200 Dementia: Alzheimer disease, Huntington disease, prion diseases and other causes 202 15 Strong family history – typical Mendelian disease 209 Cystic fibrosis 210 Duchenne and Becker muscular dystrophies 212 Neurofi bromatosis type 1 214 16 Strong family history – other inheritance mechanisms 219 Myotonic dystrophy 220 Fragile X syndrome 221 Mitochondrial disorder 222 Imprinting-related disorder 223 Chromosomal translocation 224 17 Screening for disease and for carriers 229 Prenatal screening 230 Neonatal screening 233 Carrier detection in the adult population 234 Presymptomatic screening of adults 237 18 Family history of one or more congenital malformations 241 Aetiology 242 Chromosomal disorders 243 Neural tube defects 247 Teratogenic eff ects 250 Multiple malformation syndromes 253 Part 3: Electronic databases – a user's guide 265 19 Electronic databases – a user's guide 267 Finding information regarding specifi c conditions and names of associated genes 268 Laboratories undertaking genetic testing 270 Patient information and support groups 270 Gene- and protein-specifi c sequence, structure, function and expression information 272 Nucleotide sequences and human mutations 281 Automatic primer design tools 281 Displaying map data for genes and markers 287 Online missense mutation analysis tools 288 Computer-aided syndrome diagnosis 293 Professional genetics societies 297 Th e Human Genome Project: ethics and education 297 Self-assessment – answers 305 Appendix 1: Odds, probabilities and applications of Bayes’ theorem 312 Appendix 2: Calculation of the coeffi cients of relationship and inbreeding 314 Appendix 3: Population genetics of single-gene disorders 315 Appendix 4: Legal aspects 317 Glossary 318 Index 324

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Book SynopsisTrade Review"Dorland's is one of the most comprehensive medical dictionaries on the market." -Iris Kovar-Gough, MA, MLIS(Michigan State University Libraries) Doodys Review Service

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Book SynopsisThese are the same books used in Kaplan Medical’s courses and trusted by thousands of medical students each year to succeed on the exam. The books are entirely made up of case-based scenarios, with Differential Diagnoses, Testing, Discussion, and Management. Volume 1 cases address Internal Medicine, Psychiatry, and Ethics. Volume 2 cases address Pediatrics, Obstetrics/Gynecology, Surgery, Epidemiology/Biostatistics, Patient Safety. Up-to-date. Updated biannually by Kaplan’s all-star faculty. Complete. Includes basic science correlates likely to be tested on the exam, patient management from the experts, patient safety, and population health.Learner-efficient. Case-based content (250+ in-depth cases) organised in outline format presents material for both the Foundations of Independent Practice (FIP) and Advanced Clinical Medicine (ACM) components of the examTrusted. Used by thousands of students each year to succeed on the USMLE Step 3 and COMLEX-USA Level 3.Clinical Management Review Complete 2-Book Set 2023-2024 assumes mastery of both the preclinical (discipline-based) and clinical sciences, both of which are covered in Kaplan's other bundles.

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Book SynopsisOSCEs Made Easy is tailored for undergraduate medical students and postgraduate medical trainees. It is a practical guide on how to prepare rigorously and systematically for OSCEs, and to secure yourself a high-scoring result. A compilation of personal revision notes combined with stories about what works well, the objective of this book is to provide every final-year medical student with the information we wish we had known going into OSCE revision. For what it is worth, all of us contributing to this book passed the OSCEs with distinctions!This book is not just an exam crammer. It is also an excellent resource for the first years on the clinical wards challenged by a complex patient on the cardiology ward, or for those who forgot how to properly examine a patient with a neurological complaint in the emergency room. The reader of this book will be provided with the resources to take a focused history, perform a proper examination, and prescribe and do basic procedures.

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Book SynopsisAce your medical exams with The Revision Guide to Core Clinical Medicine!Unlock your medical potential with The Revision Guide to Core Clinical Medicine - the ultimate companion for every aspiring doctor, written by graduates from the University of Cambridge. This comprehensive resource takes students through eight core specialities, from pharmacology and investigations to the diagnosis and management of conditions, helping to save time and reduce levels of stress for medical students.Truly understand and excel in the essential knowledge needed to succeed.Instead of needing multiple books for each subject area - such as different specialities, pharmacology and investigations - this exhaustive revision guide covers the key information in one convenient resource. Packed with vital information across eight core specialities, this unique book will help you ace your clinical exams.All the must-know information in one comprehensive and easy-to-understand book.

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Book SynopsisThis open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.Table of ContentsPart I. The biopsychosocial model: a diagnostic assessment.- Ch. 1. Much invoked – but deeply flawed?.- Ch.2. Locating the scientific and clinical content.- Ch. 3 The core theory problem: biopsychosocial causal interactions.- Ch. 4 The first step: updating the biomedical model.- Part II. Core non-reductionist concepts in biology and biomedicine.- Ch.5 Biology.- Ch.6 Physicalism.- Part III. Biology opens up to the BioPsychoSocial.- Ch.7 The Biomedical Model opens up to the Biopsychosocial.- Ch.8 The Psychological as Agency.- Ch.9 Conditions of Agency.- Ch.10 The socio-political : who gets to control what?.- Ch.11 Biopsychosocial systems.- Part IV. Biopsychosocial conditions of health and disease.- Chapter 12. Conditions of biological, psychological and social life.- Chapter 13. Biopsychosocial conceptualisation of health conditions.- Chapter 14. Locating causes in biopsychosocial systems.- Chapter 15. Compare and contrast physical and mental health conditions.- Ch.16 Locating the Biopsychosocial Model.

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Book SynopsisThis book serves as a tool for general psychiatrists, medical students, residents, and fellows looking for a clinically relevant and high-yield overview of addiction psychiatry in preparation for their board exams – or for everyday clinical practice. Written by expert educators in addiction psychiatry, the text is organized by substances misused and populations affected. This book serves as both a primary learning tool for those new to the field, as well as a reference for those working in addiction treatment. Each chapter begins with summaries of high yield clinical pearls, followed by general information including treatment, and then ends with accompanying board-style review questions. The scope includes understanding substances of misuse and substance use disorders (SUDs), how to evaluate, diagnose, and monitor SUDs, how to treat SUDs both pharmacologically and behaviorally, and critical information for specific populations of patients. Absolute Addiction Psychiatry for Clinical Practice and Review is an excellent resource for all medical students, residents, fellows, and professionals taking certification exams in addiction, including those in psychiatry, addiction medicine, emergency medicine, internal medicine, pain medicine, and others. The chapter "Laboratory Testing for Substance Use Disorders" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.Table of ContentsPart 1- Diagnosis, Treatment Modalities and Settings, Recovery 1. Evaluation and diagnosis of Substance Use Disorder 2. Addiction Treatment Settings and Levels of Care 3. Recovery from Addiction and Treatment Moniotring 4. Non-pharmacologic Treatment across Substances 5. Special Focus: Issues in the US Opioid Epidemic Part 2- Substances and their Treatments 6. Nicotine 7. Alcohol 8. Benzodiazepines 9. Cannabis 10. Opioids 11. Stimulants- Cocaine and Amphetamines 12. Steroids, Dissociatives, Club Drugs, Inhalants, Hallucinogens Part 3- Populations 13. Adolescents and Students 14. Women and Pregnancy 15. Lesbian, Gay, Bisexual, Trans (LGBT) 16. Underserved Populations 17. Older Adults 18. Co-occurring Medical Disorders 19. Co-occurring Psychiatric Disorders

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Book SynopsisThe previous edition of The Bethesda System for Reporting Thyroid Cytopathology provided important updates and advances in the practice of thyroid cytopathology. It was inspired by new developments in the field of thyroid cytopathology since the publication of the first edition in 2010. These included revised clinical guidelines for the management of patients with thyroid nodules, the introduction of molecular testing as an adjunct to cytopathologic examination, and the reclassification of the non-invasive follicular variant of papillary thyroid carcinoma as non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). This new third edition provides updates to the current reporting terminology and diagnostic criteria, including new information on ancillary molecular testing, as well as imaging findings and clinical management. This book provides a more unified approach to diagnosing and reporting thyroid FNA interpretations. It simplifies the reporting structure by settling on just one name for each of the six categories and aligning terminology with the most recent classification of thyroid tumors by the World Health Organization. Written by experts in the field, The Bethesda System for Reporting Thyroid Cytopathology, Third Edition aims to inspire advances in thyroid cytopathologic diagnosis and the betterment of patients with thyroid nodular disease. It serves as a reference guide not just for pathologists, but also endocrinologists, surgeons, and radiologists. Table of Contents

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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Book SynopsisTable of Contents1. Lessons Learnt from History of Rheumatic Heart Diseases 2. Rheumatic Fever and Rheumatic Heart Disease: A 4-century Review with Special Reference to India 3. Epidemiology of Group a Streptococcal Infections, Rheumatic Fever, and Rheumatic Heart Disease 4. Can We Change the Epidemiological Trend of Rheumatic Heart Disease in India? 5. Etiopathogenesis and Management of Streptococcal Infection 6. Laboratory Diagnosis of Group A B-hemolytic Streptococcal Infections 7. Etiopathogenesis and Pathology of Carditis in Rheumatic Fever 8. Pathology of Chronic Rheumatic Heart Disease 9. Etiopathogenesis, Clinical Manifestations, and Diagnosis of Acute Rheumatic Fever 10. Cardiac Complications of Acute Rheumatic Fever 11. Role of Echocardiography in Diagnosis of Carditis in Acute Rheumatic Fever 12. Clinical Profile of Rheumatic Heart Disease 13. Role of Echocardiography in Rheumatic Heart Disease 14. Consensus and Controversies in the Management of Acute Rheumatic Fever: Introducing Armor to Prevent and Protect 15. Medical Management of Rheumatic Heart Disease and Management during Pregnancy, Noncardiac Surgery, and Infective Endocarditis 16. Echocardiographic Screening for Rheumatic Heart Disease 17. Prevention and Vaccine for Rheumatic Fever: How Far are We? 18. Natural History of Rheumatic Fever and Rheumatic Heart Disease 19. Nonsurgical Management of Rheumatic Heart Disease 20. Transcatheter Treatment of Rheumatic Mitral Stenosis in Pediatric Age Group 21. Surgical Management of Rheumatic Heart Disease 22. Rheumatic Fever, Rheumatic Heart Disease Registry, and Control Program

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Book SynopsisTable of Contents1. What is an Echo? 2. Conventional Echo 3. Color Doppler Echo 4. Echo Windows 5. Normal Views and Values 6. Newer Modalities in Echo 7. Ventricular Dysfunction 8. Cardiomyopathies 9. Coronary Artery Disease 10. Systemic Hypertension 11. Pulmonary Hypertension 12. Diseases of Aorta 13. Congenital Diseases 14. Valvular Diseases 15. Pericardial Diseases 16. Endocardial Diseases 17. Intracardiac Masses 18. Thromboembolic Diseases 19. Systemic Diseases

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Book SynopsisThe femur, or thigh bone, is the only bone in the thigh and is the longest bone in the body. It acts as the site of origin and attachment for many muscles and ligaments, and the head forms a ball and socket joint with the hip.The femoral neck connects the femoral shaft with the femoral head. Femoral neck fractures are a type of intracapsular hip fracture the junctional location makes the neck prone to fracture.TheFemoral Neck System(FNS) addresses clinical challenges associated with thefixationoffemoral neckfractures.Authored by a team of highly experienced trauma surgeons and orthopaedic specialists, this book provides a comprehensive overview of the FNS, detailing its design, biomechanical principles, clinical applications, and rehabilitation protocols.The book begins with a detailed examination of femoral neck fractures, including definitions, classifications, epidemiology, and incidence rates, as well as comparative analysis of various fixation methods.The next chapter covers design and components of implants, including screws, plates, and locking mechanisms.The following sections provide step-by-step surgical procedures for femoral neck fracture fixation, explaining positioning, intraoperative considerations, tips for optimal implant placement, and postoperative care and rehabilitation.The book concludes with discussion on common complications and their management, clinical outcomes and studies, and future perspectives and innovations.Compiling the latest data, research and expert opinions, chapters feature anecdotal notes for the fixation system, pearls, charts, figures, and diagrams, to provide an invaluable resource for specialists involved in the management of femoral neck fractures.

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Book SynopsisThe third edition has been fully revised to provide the most recent advances in chemical peeling. Topics new to this edition include lip peels, periocular peels, nail peels, hand peels, and body peels. There is also discussion on combining peels with other procedures such as lasers and microneedling, to optimise results.

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Book SynopsisThe OSCEs have become a part of most examinations in Critical Care Medicine. This book will be of great help to the examinees. The contents have been divided into two sections one is Questions and the second is Answers. It contains chapters on Respiratory Medicine, Neurology, Nephrology, Microbiology and Infection Control, Hemodynamics, Drugs, Biochemistry, Miscellaneous, and Case Scenarios. Contains nearly 330 questions with model answers. Questions range from the old tests, new techniques and devices, and results of laboratory and other investigations. Also covers questions on all organ systems and different ways these systems may be affected by the disease. The answers are structured from examination point-of-view. These will help the examinees in developing the skills to face the objective structured clinical examinations (OSCEs) in their examination. Table of ContentsQUESTIONS 1. Respiratory Medicine 2. Neurology 3. Nephrology 4. Microbiology and Infection Control 5. Hemodynamics 6. Drugs 7. Biochemistry 8. Miscellaneous 9. Case Scenarios ANSWERS 1. Respiratory Medicine 2. Neurology 3. Nephrology 4. Microbiology and Infection Control 5. Hemodynamics 6. Drugs 7. Biochemistry 8. Miscellaneous 9. Case Scenarios

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Book SynopsisIn an interesting survey amongst doctors, fibromyalgia was considered the least prestigious disease. Although this survey was done in a Scandinavian country and was done more than 13 years ago, the grim situation is still the same today all over the world. Patients suffering with fibromyalgia feel that they are not believed and they are not listened to. Despite knowledge being gathered on this disease for a few centuries, and having definite diagnostic criteria and management pathways, the healthcare system still fails many patients who are left without a diagnosis or treatment plan. Fibromyalgia is a disease that causes widespread pain in many areas of the body and has significant accompanying symptoms like fatigue, waking unrefreshed and cognitive symptoms. Fibromyalgia affects patients as a whole including their cognitive performance, physical skills, psychological status, ability to work and social life. It can present as a part of the spectrum of functional pain syndromes, often accompanied by other systemic conditions such as irritable bowel syndrome, headaches and chronic fatigue. It is estimated that 1 in 20 can suffer with this debilitating condition. This textbook will cover the condition in great detail and is written in an easy-to-understand style. Doctors, nurses, medical students, physiotherapists, occupational therapists, psychologists, and other healthcare professionals will find this book informative. Patients who suffer from fibromyalgia will also find it useful to understand their medical condition; the book will help to direct them to specific treatment strategies, explaining the benefit and risk in detail. As this is a common chronic pain presentation, it will be of immense use to candidates preparing for examinations conducted by the Royal College of Anaesthetists, UK (FRCA), Faculty of Pain Medicine, UK (FFPMRCA), American Board of Anesthesiology (AB), College of Anaesthesiologists of Ireland (FCAI), European Society of Anaesthesiology and Intensive Care (EDAIC), Australian and New Zealand College of Anaesthetists (FANZA), World Institute of Pain (FIPP/CIPS), Canadian Board exams, National Board of Examinations of India (Dip NB) and other competitive exams across the globe. The author is a senior consultant in pain medicine practising in the United Kingdom and is consulted by thousands of chronic pain patients every year. He has won many educational awards including a national innovative award in pain medicine. One of his innovations is published in the list of examples of excellence by the Faculty of Pain Medicine, London. He has lectured at many international, national and regional meetings, and is a regular invited expert lecturer in public groups and fibromyalgia patient support groups. He has also published many articles and textbooks on pain medicine.

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a huge range and FREE tracked UK delivery on ALL orders.

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Book Synopsis

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Book Synopsis

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Book SynopsisRecent innovations, including deep brain stimulation and new medications, have significantly improved the lives of people who have Parkinson's disease. Nevertheless, patients and families continue to face many challenges. This book is suitable for reliable advice about medical, emotional, and physical issues.Trade ReviewThe best comprehensive guide on Parkinson's disease I have ever read. If I were suggesting a book for my primary care physician to read on Parkinson's disease, this would be the one. APDA Young Parkinson's Newsletter Patients and their loved ones will find this practical guide the perfect complement to a physician's care. Publishers WeeklyTable of ContentsPrefacePart I: Introduction1. What Is Parkinson's Disease?2. Who Gets Parkinson's Disease?Part II: Signs and Symptoms of Parkinson's Disease3. Early Symptoms4. Moderate Parkinson's Disease5. Advanced Parkinson's Disease6. Behavioral Changes and Psychiatric Symptoms7. Young-Onset Parkinson's DiseasePart III: Diagnosing Parkinson's Disease8. How a Diagnosis Is Made9. Types of Parkinsonism10. Diagnosing Other Neurologic ProblemsPart IV: Treatment of Parkinson's Disease11. How the Brain Works and How TreatmentWorks12. Choosing the Correct Medications13. Drug Therapies14. Exercise and Rehabilitation Therapy15. Diet and Complementary/AlternativeTherapies16. Surgical TreatmentsPart V: Other Issues17. Illness, Hospitalization, and Parkinson's Disease18. Parkinson's Disease Research19. Questions and AnswersResourcesIndex

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Book SynopsisTable of ContentsChapter 1. Understanding Liver Disease Chapter 2. Diagnosing Liver Disease Chapter 3. What Is Viral Hepatitis? Chapter 4. Understanding Hepatitis B Chapter 5. Understanding Hepatitis C Chapter 6. Alcohol and the Liver Chapter 7. Non-Alcoholic Fatty Liver Disease Chapter 8. Other Causes of Liver Diseases Chapter 9. Complications of Liver Disease Chapter 10. Liver Cancer Chapter 11. Liver Transplantation Chapter 12. Liver Health Patient Resources Index

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Book SynopsisSelected as a Doody's Core Title for 2022 and 2023! For more than 30 years, Designing Clinical Research has set the standard as the most practical, authoritative guide for physicians, nurses, pharmacists, and other practitioners involved in all forms of clinical and public health research. Using a reader-friendly writing style, Drs. Warren S. Browner, Thomas B. Newman, Steven R. Cummings, Deborah G. Grady, Alison J. Huang, Alka M. Kanaya, and Mark J. Pletcher, all of the University of California, San Francisco, provide up-to-date, commonsense approaches to the challenging judgments involved in designing, funding, and implementing a study. This state-of-the-art fifth edition features new figures, tables, and design, as well as new editors, new content, and extensively updated references to keep you current. Covers clinical research in its many forms, including clinical trials, observational studies, translational science, and patient-oriented research. Presents epidemiologic terms and principles and advanced conceptual material in a practical and reader-friendly manner. Discusses key changes in the field, including confounding and directed acyclic graphs, surrogate outcomes and biomarkers, instrumental variables and Mendelian randomization, regression discontinuity designs, alternative data sources, AI and machine learning, pilot studies, as well as an update on P values and Bayesian analysis.. Covers modifications of classic randomized trials, such as pre/post, interrupted time series, difference-in-differences, stepped wedge and cluster randomized designs, as well as randomized trials in health systems. Adds new chapters on qualitative approaches to clinical research and on community-engaged research Enrich Your eBook Reading Experience Read directly on your preferred device(s),such as computer, tablet, or smartphone Easily convert to audiobook,powering your content with natural language text-to-speech

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Book SynopsisCurrent, comprehensive, and focused, the bestselling Oxford Handbook of Acute Medicine returns for its fourth edition.Thoroughly revised and updated throughout, this trusted, quick-reference guide includes the latest evidence-based guidelines and recommended management of medical emergencies alongside new figures and clinical tips from experienced authors and a team of dedicated specialist reviewers. With a new chapter on acute medicine and the older patient, and even more distilled key points and practice tips, it is accessible to all members of the multidisciplinary team and practitioners across an even wider range of specialties. The Oxford Handbook of Acute Medicine remains the must-have resource for all those dealing with acute illness.Your practical guide to the presentation, causes, and management of the acutely ill patient, this Handbook will take you step-by-step through the management of the patient while awaiting specialist help, and beyond, with details of specialist treatmTrade ReviewReview from previous edition Continuing on the tradition of excellence that define the Oxford Handbooks, this little book is ideal for all stages of medical training... This book is definitely one to add to your collection of core texts. * Northwing *Table of Contents1: Cardiac emergencies 2: Respiratory emergencies 3: Gastroenterological emergencies 4: Renal emergencies 5: Shock 6: Neurological emergencies 7: Infectious diseases 8: Emergencies in HIV-positive patients 9: Endocrine emergencies 10: Haematological emergencies 11: Rheumatological emergencies 12: Dermatological emergencies 13: Psychiatric emergencies 14: Drug overdoses 15: Practical procedures 16: Differential diagnosis 17: Acute medicine and the older patient

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Book SynopsisSelected as a Doody's Core Title for 2022 and 2023! Reflecting the trusted expertise of Dr. John B. West and Dr. Andrew M. Luks, West’s Pulmonary Pathophysiology: The Essentials, Tenth Edition offers accessible explanations of disease processes that affect the respiratory system. This best-selling companion to West’s Respiratory Physiology: The Essentials, 11th Edition, has served generations of students and practitioners who work with respiratory patients, presenting vital knowledge in a concise, straightforward manner that’s easy to understand. Building on this legacy of success, the tenth edition is updated throughout with the latest clinical perspectives, new images, clinical vignettes, and enhanced USMLE-style review questions to help students excel in today’s changing healthcare practice. UPDATED! Clinical Vignettes with open-ended questions demonstrate the real-world application of basic science and strengthen students’ self-assessment. UPDATED! Radiographs, CT images, and color histopathologic sections clarify diagnostic and therapeutic approaches. UPDATED! USMLE-style multiple-choice questions, with answers, at the end of each chapter reveal areas requiring further study and boost students’ test-taking confidence. Clinical features/notes boxes provide efficient, bulleted review for key diseases. End-of-chapter Key Concepts reviews reinforce essential chapter information at a glance. Appendices provide fast access to symbols, units, and normal values; further readings; and answers to multiple-choice and Clinical Vignette questions. Online video lectures, available via YouTube, engage students in the material and clarify challenging textbook concepts.

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Book SynopsisCovering the core concepts, activities and approaches involved in medical education, Medical Education at a Glance provides a concise, accessible introduction to this rapidly expanding area of study and practice.Table of ContentsPreface vii Acknowledgements viii About the editors ix Contributors x Part 1 Overview and broad concepts 1 1 What is medical education? 2 2 Stages of medical education 4 3 Evidence-guided education 6 4 Learning theories: paradigms and orientations 8 5 Learning theories and clinical practice 10 6 The curriculum 12 7 Planning and design 14 8 Equality, diversity and inclusivity 16 9 Principles of selection 18 10 Evaluation 20 11 Educational leadership 22 12 International perspectives 24 Part 2 Medical education in practice 27 13 Large group teaching: planning and design 28 14 Large group teaching: delivery 30 15 Small group teaching: planning and design 32 16 Small group teaching: delivery 34 17 Clinical teaching: planning and design 36 18 Clinical teaching: delivery 38 19 Simulation: planning and design 40 20 Simulation: delivery 42 21 Patient involvement in education 44 22 Ward-based and bedside teaching 46 23 Learning and teaching in ambulatory settings 48 24 Teaching in the operating theatre 50 25 Interprofessional education 52 26 Reflective practice 54 27 Teaching clinical reasoning 56 28 Professionalism 58 29 Peer learning and teaching 60 30 Communication 62 31 Problem-based and case-based learning 64 32 Learner support 66 33 Supporting professional development activities 68 34 Mentoring and supervision 70 35 e-Learning 72 36 Social media 74 Part 3 Assessment and feedback 77 37 Feedback 78 38 Principles of assessment 80 39 Written assessments 82 40 Assessment of clinical skills 84 41 Work-based assessment 86 42 Assessing professionalism 88 43 Portfolios 90 44 Setting pass marks 92 45 Developing yourself as a medical educator 94 Further reading/resources 96 References 101 Index 107

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Book SynopsisA new volume in the bestselling Pocket Notebook series, Pocket Addiction Medicine delivers highly relevant coverage of this widespread and increasing health care problem in an easily portable source. Edited by physician leaders in Addiction Medicine, Drs. Sarah E. Wakeman, Joshua D. Lee, and Anika Alvanzo and co-published with the American Society of Addiction Medicine (ASAM), this handbook provides must-know information on everything from screening for and diagnosis of substance use disorder to managing intoxication and withdrawal, to ongoing treatment of substance use disorder, including caring for special populations—all designed for quick reference at the point of care. Using the popular, easy-access Pocket Notebook format, it puts key clinical information about a broad range of issues in addiction medicine at your fingertips in seconds. Contains up-to-date content in outline format, with bulleted lists, tables, and algorithms for quick reference. Covers the most essential topics in addiction medicine including screening, diagnosis, treatment, toxicology testing, harm reduction, and many more. Progresses logically from basic epidemiology, to assessment, diagnosis, and treatment. Consult this high-yield handbook by diagnosis, such as opioid use disorder, alcohol use disorder, or stimulant use disorder; or by special topic, such as preventing overdose and infectious complications associated with injection drug use, caring for pregnant people with substance use disorder, treatment of pain and opioid use disorder, or understanding recovery supports. A portable and authoritative resource for physicians and trainees in primary care and other specialty areas, as well as students and other healthcare professionals.

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book Synopsis

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