Clinical and internal medicine Books
John Wiley and Sons Ltd Lee Textbook Vol 2
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£40.10
Basic Books VRx: How Virtual Therapeutics Will Revolutionize
Book SynopsisA virtualist is a doctor who specializes in virtual medicine. She uses tools like VR headsets, spatial acoustics, haptic feedback, and even olfactory mimicry to induce reactions in patients' bodies that help treat a variety of physiological and psychological conditions, from chronic pain, to compulsive behavior, without the use of pharmaceuticals or surgical techniques. Virtualists don't exist yet, but after reading VRx they just might. In recent years, scientists have established that people's perceptions - their subjective experiences of the world - influence how their bodies work. We typically have little control over our perceptions, particularly when we are sick. But what could we do if we did? In VRx Brennan Spiegel introduces readers to a new kind of medicine, called virtual therapeutics, answering exactly this question, using technology that is already available.It works through two basic but powerful psychological concepts: embodied cognition, the idea that thought processes involve the whole body, not just the brain; and presence, the ability of virtual reality to trick your body into thinking it's somewhere that it isn't, or can do something that it can't usually do. VRx takes readers on a mindbending journey through the ways in which these deep connections between our minds and our bodies are being put to good use. We learn about the woman who endures an exceptionally painful labor by completing breathing exercises on a digital beach, the schizophrenic patient who literally confronts the demon inside his head, the burn victims who are able to manage their pain better after traversing snowy virtual landscapes, and the doctor who confronted his own fear of mortality by watching himself die. Brimming with extraordinary stories of the power of virtual therapeutics to treat both physical and psychological conditions, VRx offers nothing short of a completely new way of healing.
£29.90
American Society for Microbiology Snyder and Champness Molecular Genetics of
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£100.80
AHA Press ICD-10-CM and ICD-10-PCs Coding Handbook Without
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£120.34
John Wiley and Sons Ltd Glycobiology of the Immune Response, Volume 1253
Book SynopsisCarbohydrates are ubiquitous, essential molecules, as important as nucleic acids and proteins yet less well understood. Mounting data demonstrate that microbial and mammalian glycans and their protein-binding partners (lectins) play central roles in all innate and adaptive immune responses. Indeed, programmed remodeling of host glycans can modulate infection, autoimmunity, and cancer, while microbial glycoconjugates can serve as canonical innate receptor agonists that induce B cell and T cell activation. Glycobiology of the Immune Response explores the integration of state-of-the-art glycobiology and immunology to raise awareness of the multifaceted roles of glycans and lectins in the immune system NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.Trade Review“Glycobiology of the Immune Response explores the integration of state-of-the art glycobiology and immunology to raise awareness of the multifaceted roles of glycans and lectins in the immune system.” (European Journal of Immunology, 1 December 2012) Table of ContentsGlycobiology of immune responses 1 Gabriel A. Rabinovich, Yvette van Kooyk and Brian A. Cobb Multifarious roles of sialic acids in immunity 16 Ajit Varki and Pascal Gagneux Siglecs as sensors of self in innate and adaptive immune responses 37 James C. Paulson, Matthew S. Macauley and Norihito Kawasaki Interleukin-2, Interleukin-7, T cell-mediated autoimmunity, and N-glycosylation 49 Ari Grigorian, Haik Mkhikian and Michael Demetriou T cells modulate glycans on CD43 and CD45 during development and activation, signal regulation, and survival 58 Mary C. Clark and Linda G. Baum Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells 68 Bo Pei, Jose Luis Vella, Dirk Zajonc and Mitchell Kronenberg Gelectins in acute and chronic inflammation 80 Fu-Tong Liu, Ri-Yao Yang and Daniel K. Hsu Mechanisms underlying in vivo polysaccharide-specific immunoglobulin responses to intact extracellular bacteria 92 Clifford M. Snapper CD33-related siglecs as potential modulators of inflammatory responses 102 Paul R. Crocker, Sarah J. McMillan and Hannah E. Richards Sulfated glycans control lymphocyte homing 112 Hiroto Kawashima and Minoru Fukuda Acute phase glycoproteins: bystanders or participants in carcinogenesis? 122 Eugene Dempsey and Pauline M. Rudd Glycans, galectins, and HIV-1 infection 133 Sachiko Sato, Michel Ouellet, Christian St-Pierre and Michel J. Tremblay An evolutionary perspective on C-type lectins in infection and immunity 149 Linda M. van den Berg, Sonja I. Gringhuis and Teunis B. H. Geijtenbeck Integrated approach toward the discovery of glycol-biomarkers of inflammation-related diseases 159 Takashi Angata, Reiko Fuijinawa, Ayako Kurimoto, Kazuki Nakajima, Masaki Kato, Shinji Takamatsu, Hiroaki Korekane, Cong-Xiao Gao, Kazuaki Ohtsubo, Shinobu Kitazume and Naoyuki Taniguchi Novel roles for the IgG Fc Glycan 170 Robert M. Anthony, Fredrik Wermeling and Jeffrey V. Ravetch The effect of galectins on leukocyte trafficking in inflammation: sweet or sour? 181 Dianne Cooper, Asif J. Iqbal, Beatrice R, Grittens, Carmela Cervone and Mauro Perretti Engineering cellular trafficking via glycosyltransferase-programmed stereosubstitution 193 Robert Sackstein The expanding role of α2-3 sialylation for leukocyte trafficking in vivo 201 Markus Sperandio Beyond glycoproteins as galectin counterreceptors: effector T cell growth control of tumors via ganglioside GM1 206 Robert W. Ledeen, Gusheng Wu, Sabine André, David Bleich, Guillementte Huet, Herbert Kaltner, Jürgen Kopitz and Hans-Joachim Gabius Online only Polarization of host immune responses by helminth-expressed glycans Donald Harn Jr., Smanla Tundup and Leena Srivastava Carbohydrate-recognition in the immune system: contributions of NGL-based microarrays to ligand discovery Ten Feizi Diversity in recognition of glycans by F-type lectins and galectins: molecular, structural, and biophysical aspects Gerardo R. Vasta, Hafiz Ahmed, Mario A. Bianchet, José A. Fernández-Robledo and L. Mario Amzel
£36.95
John Wiley and Sons Ltd Environmental Stressors in Biology and Medicine,
Book SynopsisThis volume stems from the Second International Conference on Environmental Stressors in Biology and Medicine, which occurred October 5-7, 2011 in Siena, Italy. Included are short reviews and perspectives on the basic mechanisms of environmental stressors; physical and chemical stressors and related diseases; air pollutants and related diseases; protection afforded by food and pharmaceuticals; and food as a source of stressors. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.Table of ContentsOmics approaches in cystic fibrosis research: a focus on oxylipin profiling in airway secretions Jason P. Eiserich Jun Yang Brian M. Morrissey Bruce D. Hammock Carroll E. Cross 1 Nitric oxide signaling in the brain: translation of dynamics into respiration control and neurovascular coupling Joao Laranjinha Ricardo M. Santos Cátia F. Lourenco Ana Ledo RuiM. Barbosa 10 Physiological functions of GPx2 and its role in inflammation-triggered carcinogenesis Regina Brigelius-Flohé Anna Patricia Kipp 19 Molecular medicine and the development of cancer chemopreventive agents Alberto Izzotti 26 Experimental basis for discriminating between thermal and athermal effects of water-filtered infrared A irradiation Tobias Jung Tilman Grune 33 Acrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary disease Nadia Moretto Giorgia Volpi Fiorella Pastore Fabrizio Facchinetti 39 Sarcopenia and smoking: a possible cellular model of cigarette smoke effects on muscle protein breakdown Oren Rom Sharon Kaisari Dror Aizenbud Abraham Z. Reznick 47 The link between altered cholesterol metabolism and Alzheimer's disease Paola Gamba Gabriella Testa Barbara Sottero Simona Gargiulo Giuseppe Poli Gabriella Leonarduzzi 54 Rottlerin and curcumin: a comparative analysis Emanuela Maioli Claudia Torricelli Giuseppe Valacchi 65 Plant polyphenols and human skin: friends or foes Liudmila Korkina Chiara De Luca Saveria Pastore 77 Flavonoids and metabolic syndrome Monica Galleano Valeria Calabro Paula D. Prince María C. Litterio Barbara Piotrkowski Marcela A. Vazquez-Prieto Roberto M. Miatello Patricia I. Oteiza Cesar G. Fraga 87 Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia Carmela Spagnuolo Maria Russo Stefania Bilotto Idolo Tedesco Bruna Laratta Gian Luigi Russo 95 Cigarette smoke and ozone effect on murine inflammatory responses Concetta Gardi Giuseppe Valacchi 104 Age-related changes in cellular protection, purification, and inflammation-related gene expression: role of dietary phytonutrients Angela Mastaloudis Steven M. Wood 112 The role of oxidative stress in Rett syndrome: an overview Claudio De Felice Cinzia Signorini Silvia Leoncini Alessandra Pecorelli Thierry Durand Giuseppe Valacchi Lucia Ciccoli Joussef Hayek 121 Emerging topics in cutaneous wound repair Giuseppe Valacchi Iacopo Zanardi Claudia Sticozzi Velio Bocci Valter Travagli 136 Corrigendum for Ann. N.Y. Acad. Sci. 1236: 30-43 145
£116.85
John Wiley and Sons Ltd Barriers and Channels Formed by Tight Junction
Book SynopsisTight junctions between epithelial and endothelial cells form selective barriers and paracellular channels and regulate paracellular transport of solutes, immune cells, and drugs. More specifically, tight junctions consist of proteins that laterally interconnect neighboring cells of epithelia and endothelia. Certain proteins seal the tight junction, so that a nearly impermeable barrier develops, whereas others form channels that allow for permeation between the cells. Recent investigations have focused on tight junction proteins, belonging to the claudin family (claudins-1 to -27 in humans) and the newly defined group of TAMP (three proteins: occludin, Marvel-D2, and tricellulin). Barriers and Channels Formed by Tight Junction Proteins I showcases work in this area clustered around three major themes: the molecular properties of tight junctions, for example, the role of the claudin family of proteins and the formation of ion and charge-selective channels; the regulation of tight junction and barrier functions via genetic mechanisms and scaffold protein mediation; and the functional role of the tight junction in various tissues, such as the skin, lungs, endothelia, and nervous system NOTE: Annals volumes are available for sale as individual books or as a journal. For informatio.n on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. Table of Contents1. Perspectives on tight junction research Jörg-Dieter Schulzke, Dorothee Günzel, Lena J. John, and Michael Fromm Molecular properties of the tight junction 20. Charge-selective claudin channel Susanne M. Krug, Dorothee Günzel, Marcel P. Conrad, In-Fah M. Lee, Salah Amasheh, Michael Fromm, and Alan S. L. Yu 29. Claudin-derived peptides are internalized via specific endocytosis pathways Denise Zwanziger, Christian Staat, Anuska V. Andjelkovic, and Ingolf E. Blasig 38. A phosphorylation hotspot within the occluding C-terminal domain Max J. Dörfel and Otmar Huber 45. Determinants contributing to claudin ion channel formation Anna Veshnyakova, Susanne M. Krug, Sebastian L. Mueller, Jörg Piontek, Jonas Protze, Michael Fromm, and Gerd Krause 54. Lipolysis-stimulted lipoprotein receptor: a novel membrane protein of tricellular tight junctions Mikio Furuse, Yukako Oda, Tomohito-Higashi, Noriko Iwamoto, and Sayuri Masuda 59. Overexpression of claudin-5 but not claudin-3 induces formation of trans-interaction-dependent multilamellar bodies Jan Rossa, Dorothea Lorenz, Martina Ringling, Anna Veshnyakova, and Joerg Piontek 67. Association between segments of zonula occludens proteins: live-cell FRET and mass spectrometric analysis Christine Rueckert, Victor Castro, Corinna Gagell, Sebastian Dabrowski, Michael Schümann, Eberhard Krause, Ingolf E. Blasig, and Reiner F. Haseloff 77. Dynamic properties of the tight junction barrier Christopher R. Weber Regulation of the tight junction and barrier function 85. Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cells Takashi Kojima and Norimasa Sawada 93. The role for protein tyrosine phosphatase nonreceptor type 2 in regulating autophagosome formation Michael Scharl and Gerhard Rogler 103. Caveolin binds independently to claudin-2 and occluding Christina M. Van Itallie and James M. Anderson 108. Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2 Declan F. McCole 115. Intracellular mediators of JAM-A-dependent epithelial barrier function Ana C. Monteiro and Charles A. Parkos 125. Cingulin, paracingulin, and PLEKHA7: signaling and cytoskeletal adaptors at the apical junctional complex Sandra Citi, Pamela Pulimeno, and Serge Paschoud 133. ZO-2, a tight junction scaffold protein involved in the regulation of cell proliferation and apoptosis Lorenza Gonzalez-Mariscal, Pablo Bautista, Susana Lechuga, and Miguel Quiros 142. From TER to trans- and paracellular resistance: lessons from impedance spectroscopy Dorothee Günzel, Silke S. Zakrzewski, Thomas Schmid, Maria Pangalos, John Wiedenhoeft, Corinna Blasse, Christopher Ozboda, and Susanne M. Krug Tight junctions in skin, lung, endothelia, and nervous tissues 152. Diverse type of junctions containing tight junction proteins in stratified mammalian epithelia Werner W. Franke and Ulrich-Frank Pape 158. Barriers and more: functions of tight junction proteins in the skin Nina Kirschner and Johanna M. Brandner 167. Roles for claudins in alveolar epithelial barrier function Christian E. Overgaard, Leslie A. Mitchell, and Michael Koval 175. Claudins and alveolar epithelial barrier function in the lung James A. Frank 184. Relevance of endothelial junctions in leukocyte extravasation and vascular permeability Dietmar Vestweber 193. Involvement of claudins in zebrafish brain ventricle morphogenesis Jingjing Zhang, Martin Liss, Hartwig Wolburg, Ingolf E. Blasig, and Salim Abdelilah-Seyfried 199. Modulation of tight junction proteins in the perineurium for regional pain control D. Hackel, A. Brack, M. Fromm, and K. L. Rittner
£97.85
Workman Publishing Flu Therapy: A Natural and Herbal Approach: (A
Book SynopsisSince 1973, Storey's Country Wisdom Bulletins have offered practical, hands-on instructions designed to help readers master dozens of country living skills quickly and easily. There are now more than 170 titles in this series, and their remarkable popularity reflects the common desire of country and city dwellers alike to cultivate personal independence in everyday life.
£6.92
American Academy of Professional Coders 2020 ICD-10-CM Expert: Diagnosis Codes for
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£108.64
American Academy of Professional Coders 2021 HCPCS Level II Expert: Service/Supply Codes
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£102.92
Black Rabbit Books Disgusting Medical Jobs
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£10.44
Amicus Learning My Life with Asthma
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£35.70
Amicus Ink Mi Vida Con Asma
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£10.44
American Society for Microbiology Gram-Positive Pathogens
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£136.75
Bancroft Press Cry Unheard: New Insights into the Medical
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£22.32
Mac Keith Press Early Detection and Early Intervention in
Book SynopsisThe book aims to provide a comprehensive overview of assessments and interventions applied in young children with, or at high risk, for developmental motor disorders. It provides an evidence-based practical guide for health professionals working in the field of early detection and early intervention (e.g., paediatricians and paediatric physiotherapists). Parts I & II provide an overview of the clinical picture of early detection and early intervention and the neurodevelopmental mechanisms occurring in early life are discussed, including vulnerability and plasticity. In Parts III & IV basic principles and features governing typical and atypical motor development are explained, covering not only motor development but also sensory and cognitive development. Part V summarises the methods available for assessments, including information on technical details of the tools and psychometric properties. Finally, Part VI discusses early intervention, including evidence on effectiveness, together with the application of equipment in young children with developmental motor disorders. Special attention is paid to the family and environmental adaptations.Table of ContentsAuthor Appointments vii Foreword ix Preface xi Video Captions xiii Part 1: Introduction 1 1 Introduction 3Mijna Hadders-Algra 2 Early Diagnosis and Early Intervention in the Clinic 9Leena Haataji Part 2: Developmental Neurology 23 3 Neurodevelopmental Mechanisms in Early Life 25Mijna Hadders-Algra Part 3: Typical Motor Development 39 4 Sensory, Language, Cognitive and Socio-Economic Development 41Hayley C Leonard 5 Motor Development During Foetal Life and Early Infancy 58Mijna Hadders-Algra 6 Motor Development Between 3 Months and 2 Years 70Mijna Hadders-Algra Part 4: Atypical Motor Development 97 7 Atypical Motor Development of the Foetus and Young Infant 89Mijna Hadders-Algra 8 Atypical Motor Development Between 3 Months and 2 Years 99Mijna Hadders-Algra and Lindsay Pennington Part 5: Diagnostics: Assessment of Neuromotor Conditions In Early Childhood 113 9 Psychometric Properties of Standardized Tests 115Barbara Sargent 10 Assessments in the Neonatal Period and Early Infancy 124Alicia Jane Spittle and Mijna Hadders-Algra 11 Assessment of Infants and Toddlers 144Annette Majnemer, Laurie Snider and Mijna Hadders-Algra Part 6: Early Intervention 171 12 Early Intervention: What About the Family? 173Peter Rosenbaum, Monika Novak-Pavlic, Schirin Akhbari Ziegler and Mijna Hadders-Algra 13 Early Intervention in the Neonatal Period 185Mijna Hadders-Algra 14 Early Intervention in the First 2 Years Post-Term 198Mijna Hadders-Algra 15 Environmental Adaptations 228Gunilla Thunberg, Roslyn Livingstone, Margaret Buchholz and Debra Field 16 Concluding Remarks 242Mijna Hadders-Algra Index 247
£76.50
Kohlhammer Neurofeedback: Theoretische Grundlagen -
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£56.05
Kohlhammer Klinische Elektromyographie Und Neurographie -
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£169.10
£304.00
Kohlhammer Depression ALS Storung Des Gleichgewichts: Wie
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£38.17
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Thyroid Disease in Adults
Book SynopsisThis book is a comprehensive guide to the assessment and management of adults with thyroid disorders in daily clinical practice. All important aspects and disorders are considered. Relevant information on basic anatomy, embryology, immunology, and physiology is included to provide a better basis for understanding the development of disease and its diagnosis and treatment. Currently available biochemical tests and other specific diagnostic tools are also considered in detail. The various common thyroid disorders are then discussed in a series of individual chapters that focus on etiology, pathophysiology, symptomatology, diagnosis, and treatment. Numerous high-quality illustrations and concise fact boxes are included. The authors are all experts with wide experience in three disciplines and a long-standing interest in thyroid disease.Trade ReviewFrom the reviews:“The authors provide a clinical handbook that covers a wide range of thyroid diseases seen in everyday practice. … This book is targeted at general practitioners, internists, and other clinicians who manage patients with thyroid dysfunction. … The large number of color pictures, graphs, and pathology pictures make this book unique and easy to read. … There are several benefits to this book. … Readers are likely to find useful clinical pearls without much searching. … it serves well as a handbook and reference.” (Rebecca L. Brown, Doody’s Review Service, August, 2011)Table of ContentsAnatomy and physiology.- Biochemical investigations.- Other investigations.- Clinical investigation of the thyroid.- Iodine and the thyroid gland in health and sickness.- Autoimmunity and the thyroid gland.- Growth regulation of the thyroid gland.- Thyroiditis, pathogenesis.- Causes of hypothyroidism.- Symptoms of hypothyroidism.- Threatment of hypothyroidism.- Subclinical hypothyroidism.- Myxoedema coma.- Causes of thyrotoxicosis.- Symptoms of thyrotoxicosis.- Treatment options in hyperthyroidism.- Graves’ disease.- Thyroid-associated ophthalmopathy.- Autonomous adenoma.- Toxic multinodular goitre.- Subclinical thyrotoxicosis.- Thyrotoxicosis in the elderly.- Thyrotoxic crisis/thyroid storm.- Thyroiditis – clinical aspects.- Subacute thyroiditis.- Other causes of thyrotoxicosis.- Non-toxic goiter.- Thyroid lumps.- Thyroid cancer.- The thyroid and pregnancy. Thyroid disease in adolescents.- Medicines and other medical preparations and the thyroid.- Thyroid hormone resistance.
£166.54
World Health Organization Pocket book of hospital care for children:
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£23.56
World Health Organization Lignes Directrices Pour Le Traitement de la
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£28.50
World Health Organization Défi de l'Obésité Dans La Région Européenne de
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£22.80
WHO Regional Office for Europe Tackling Chronic Disease in Europe: Strategies
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£33.08
Tomo Remedios Caseros Que Curan Casi Todo
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£9.95
