Cellular biology (cytology) Books
Nova Science Publishers Inc Axons: Cell Biology, Molecular Dynamics & Roles
Book SynopsisAxons are nerve fibres that typically conduct electrical impulses away from the neuron''s cell body. The function of the axon is to transmit information to different neurons, muscles and glands. In this book, the authors discuss the cell biology, molecular dynamics and role in neural repair and rehabilitation of axons. Topics include the traumatic retraction of living neural processes and their inhibitions; water translocation from the axoplasm into the glioplasm during reactive reorganisation of myelinated nerve fibres; problems and mechanisms in axonal afterdischarges; the putative role of axon cytoskeleton protein in MS repair; microtubules as a potential therapeutic target for the treatment of neurodegenerative diseases; morphometrical and molecular biological analyses of facial nerves in healthy adults and patients with facial nerve palsy; intrinsic axon growth potential; and sensory axonal guidance by chemorepulsive and chemoattractive cues in higher vertebrates.
£146.24
Nova Science Publishers Inc Lipid Rafts: Properties, Controversies & Roles in
Book SynopsisFor many years, the surface of cells was viewed as a homogeneous fluid lipid casing. However, it is now understood that the surface of cells is not homogeneous but instead contains domains selectively enriched in particular lipids and proteins. Although it is still not completely clear how these lipid platforms are formed, their existence provides a basis for the organisation of many cell processes. One possibility is that microdomain formation relies on lipid phase separation in the plane of the bilayer -- ''lipid raft'' hypothesis. Lipid rafts are compelling since they provide spontaneous organisation for signal transduction as well as intracellular sorting and targeting. What are the functions of these domains? Do they rely on specific interactions and how do they change in response to cell signalling processes? Do they help in the understanding of cell signalling and immune function and how may they be disrupted in disease processes such as neurodegeneration?
£146.24
Nova Science Publishers Inc Ganglion Cells: Morphology, Functional
Book SynopsisThe ability to observe the world around us through sight provides us with many advantages we may take for granted daily. We are able to recognise a hazard well in advance because we see it; we can find allies because we see them. Further, thanks to the perception of the world that gives us sight, we can collect information to help us develop feelings, such as trust in others, love and sensations, like beauty. However, the mechanism to enjoy this capability is really complex, starting with the structure responsible for receiving, processing and transmitting information to the brain. This book discusses the ways in which ganglion cells are used in the nervous system, as well as its morphology, functional development and role in diseases.
£106.49
Nova Science Publishers Inc Oxidative Stress: Causes, Role in Diseases &
Book SynopsisActive oxygen species are produced as inescapable by-products of a normal aerobic metabolism, and their production is further enhanced by exposure to certain environmental conditions, or as a result of some diseases. Oxidative stress is defined as an imbalance between the production of free radicals (FR) and antioxidant defences in favour of the former, which can result from an excess of prooxidant, antioxidant deficiency or both factors. There are many kinds of FR, but these can be grouped together under the name of reactive oxygen species (ROS) or reactive nitrogen species (RNS), determined by the ability of each species according to the four basic characteristics: reactivity, specificity, selectivity and diffusivity. This book aims to discuss the biological effects, role in diseases, and causes of oxidative stress. Some of the topics provided include oxidative stress in biofilms; age realtion to oxidative stress; controlling of oxidative stress in non-alcoholic steatohepatitis; and the role of nitric oxide toxicity and oxidative stress in graft versus host disease.
£182.99
Nova Science Publishers Inc New Research on Molecular Chaperones
Book SynopsisIn this book, the current advances on the functional role of molecular chaperones in protozoan''s mechanisms of response to stressful conditions, as well as an overview of studies focusing on molecular chaperones as potential targets for designing novel anti-parasitic drugs, are examined. In the second chapter, the current progress regarding the structure-function relationship as well as its association with the chaperone-like activity of the mammalian PDIA1/P4HB protein are discussed. The final chapter focuses on the cytoplasmic and nuclear functions of URI/Bud27 in different organisms.
£127.99
Nova Science Publishers Inc Properties Live Axoplasm
Book SynopsisThis book is devoted to the study of physiological properties of a living axoplasm, which, as it turns out, is hardly studied as a single organ. This study revealed a number of new physiological properties. The mechanism of simultaneous currents bidirectional axoplasm, disappearance streams and reappearance of the apical dendrites of pyramidal neurons in the brain during stress were revealed, as well as the causes of the similarity of nerve terminals regardless of their very different physiological functions. There exists proof of differences in presynaptic terminals of the postsynaptic. The reasons for the impossibility of treating transected axons using surgical sutures are discussed, and finally the cause of the absence of swelling properties in myelinated fibers with hypotension environment is solved. Some new approaches to the treatment of fibers and early manifestations of diastase nonspecific reactions are explored as well.
£113.59
Nova Science Publishers Inc Osteoclasts: Cell Biology, Functions & Related
Book Synopsis
£127.99
S Karger AG Chromosomes Genomes and Beyond Maximo E Drets
Book Synopsis
£133.86
S Chand & Co Ltd Cell Biology,Genetics, Molecular Biology: Evolution and Ecology
£999.99
Cosmo Publications Cytomorphology of Iris
Book Synopsis
£999.99
Anmol Publications Pvt Ltd Physiology of Transport
Book Synopsis
£33.74
Nova Science Publishers, Inc. Calponin and Transgelin Molecular Evolution Function Regulation and Medical Relevance
£72.24
Nova Science Publishers, Inc. The Centrosome â 150 Years of Research
£163.19
Penguin Publishing Group The Lives of a Cell Notes of a Biology Watcher
Book SynopsisElegant, suggestive, and clarifying, Lewis Thomas's profoundly humane vision explores the world around us and examines the complex interdependence of all things. Extending beyond the usual limitations of biological science and into a vast and wondrous world of hidden relationships, this provocative book explores in personal, poetic essays to topics such as computers, germs, language, music, death, insects, and medicine. Lewis Thomas writes, Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us.
£14.45
Oxford University Press Sex and the Origins of Death
Book SynopsisDeath, for bacteria, is not inevitable. Protect a bacterium from predators, and provide it with adequate food and space to grow, and it would continue living--and reproducing asexually--forever. But a paramecium (a slightly more advanced single-cell organism), under the same ideal conditions, would stop dividing after about 200 generations--and die. Death, for paramecia and their offspring, is inevitable. Unless they have sex. If at any point during that 200 or so generations, two of the progeny of our paramecium have sex, their clock will be reset to zero. They and their progeny are granted another 200 generations. Those who fail to have sex eventually die. Immortality for bacteria is automatic; for all other living beings--including humans--immortality depends on having sex. But why is this so? Why must death be inevitable? And what is the connection between death and sexual reproduction? In Sex and the Origins of Death, William R. Clark looks at life and death at the level of the cell, as he addresses such profound questions as why we age, why death exists, and why death and sex go hand in hand. Clark reveals that there are in fact two kinds of cell death--accidental death, caused by extreme cold or heat, starvation, or physical destruction, and programmed cell death, initiated by codes embedded in our DNA. (Bacteria have no such codes.) We learn that every cell in our body has a self-destruct program embedded into it and that cell suicide is in fact a fairly commonplace event. We also discover that virtually every aspect of a cell''s life is regulated by its DNA, including its own death, that the span of life is genetically determined (identical twins on average die 36 months apart, randomly selected siblings 106 months apart), that human tissue in culture will divide some 50 times and then die (an important exception being tumor cells, which divide indefinitely). But why do our cells have such programs? Why must we die? To shed light on this question, Clark reaches far back in evolutionary history, to the moment when inevitable death (death from ageing) first appeared. For cells during the first billion years, death, when it occurred, was accidental; there was nothing programmed into them that said they must die. But fierce competition gradually led to multicellular animals--size being an advantage against predators--and with this change came cell specialization and, most important, germ cells in which reproductive DNA was segregated. When sexual reproduction evolved, it became the dominant form of reproduction on the planet, in part because mixing DNA from two individuals corrects errors that have crept into the code. But this improved DNA made DNA in the other (somatic) cells not only superfluous, but dangerous, because somatic DNA might harbour mutations. Nature''s solution to this danger, Clark concludes, was programmed death--the somatic cells must die. Unfortunately, we are the somatic cells. Death is necessary to exploit to the fullest the advantages of sexual reproduction. In Sex and the Origins of Death, William Clark ranges far and wide over fascinating terrain. Whether describing a 62-year-old man having a major heart attack (and how his myocardial cells rupture and die), or discussing curious life-forms that defy any definition of life (including bacterial spores, which can regenerate after decades of inactivity, and viruses, which are nothing more than DNA or RNA wrapped in protein), this brilliant, profound volume illuminates the miraculous workings of life at its most elemental level and finds in these tiny spaces the answers to some of our largest questions.Trade ReviewAnyone who reckons that science writing is dry stuff may find their outlook broadened by this little book about the biology of death. * New Scientist *
£16.49
Oxford University Press Life Itself
Book SynopsisIn Life Itself, Boyce Rensberger, science writer for The Washington Post, takes readers to the frontlines of cell research with some of the brightest investigators in molecular, cellular, and developmental biology. Virtually all the hottest topics in biomedical research are covered here, such as how do cells and their minute components move How do the body''s cells heal wounds? What is cancer? Why do cells die? And what is the nature of life? The solutions to the most pressing challenges facing scientists today -- from the efforts to conquer disease to the quest to understand life itself -- will be found in the innermost workings of the cell.In Life Itself, Rensberger paints a colourful and fascinating portrait of modern research in this vital area, an account which will enthrall anyone interested in state-of-the-art science or the incredible workings of the human body.Trade ReviewLife Itself is a wonderfully readable digest of everything currently known about the mechanisms by which living cells perform their myriad tasks. * The New York Times Book Review *An elegant, authoritative, yet felicitously written book that will appeal to anyone who is interested in how cells work....a compelling portrait of terrestrial life in its many guises. * New Scientist *Table of Contents1. A Particle of Life ; 2. Molecular Motors ; 3. Animation ; 4. The Living-Room Cell ; 5. How Genes Work ; 6. One Life Becomes Two ; 7. Two lives Become One ; 8. Constructing a Person ; 9. Pumping Protein ; 10. Heal Thyself ; 11. In Self-Defense ; 12. Revolution ; 13. The Immortality Within
£18.49
Oxford University Press The Way of the Cell Molecules Organisms and the Order of Life
Book SynopsisWhat is life? Fifty years after physicist Erwin Schrodinger posed this question in his celebrated and inspiring book, the answer remains elusive. In The Way of the Cell, one of the world''s most respected microbiologists draws on his wide knowledge of contemporary science to provide fresh insight into this intriguing and all-important question. What is the relationship of living things to the inanimate realm of chemistry and physics? How do lifeless but special chemicals come together to form those intricate dynamic ensembles that we recognize as life? To shed light on these questions, Franklin Harold focuses here on microorganisms - in particular, the supremely well-researched bacterium E. coli - because the cell is the simplest level of organization that manifests all the features of the phenomenon of life. Harold shows that as simple as they appear when compared to ourselves, every cell displays a dynamic pattern in space and time, orders of magnitude richer than its elements. It integrates the writhings and couplings of billions of molecules into a coherent whole, draws matter and energy into itself, constructs and reproduces its own order, and persists in this manner for numberless generations while continuously adapting to a changing world. A cell constitutes a unitary whole, a unit of life, and in this volume one of the leading authorities on the cell gives us a vivid picture of what goes on within this minute precinct. The result is a richly detailed, meticulously crafted account of what modern science can tell us about life as well as one scientist''s personal attempt to wring understanding from the tide of knowledge.Trade Review"The work is like a breath of fresh air in a scientific world otherwise obsessed with excessive reductionism."--BioEssays"Witty and erudite, this scientific book hails as a literary achievement. Comprehensive and up to date, Franklin Harold traces the roots--historical, thermodynamic, and biochemical--of today's biological revolution."--Lynn Margulis, co-author (with Dorion Sagan) of both What is Life? and What is Sex?"This book helps us understand why the search for answers to the riddle 'What is life?' is a noble quest."--Howard C. Berg, author of Random Walks in Biology
£18.49
Oxford University Press Biophysics of Computation
Book SynopsisNeural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information processing in single neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive anTable of Contents1. The membrane equation ; 2. Linear cable theory ; 3. Passive dendritic trees ; 4. Synaptic input ; 5. Synaptic interactions in a passive dendritic tree ; 6. The Hodgkin-Huxley model of action-potential generation ; 7. Phase space analysis of neuronal excitability ; 8. Ionic channels ; 9. Beyond Hodgkin and Huxley: calcium, and calcium-dependent potassium currents ; 10. Linearizing voltage-dependent currents ; 11. Diffusion, buffering, and binding ; 12. Dendritic spines ; 13. Synaptic plasticity ; 14. Simplified models of individual neurons ; 15. Stochastic models of single cells ; 16. Bursting cells ; 17. Input resistance, time constants, and spike initiation ; 18. Synaptic input to a passive tree ; 19. Voltage-dependent events in the dendritic tree ; 20. Unconventional coupling ; 21. Computing with neurons - a summary
£91.20
Oxford University Press ThreeDimensional Electron Microscopy of Macromolecular Assemblies
Book SynopsisCryoelectron microscopy of biological molecules is among the hottest growth areas in biophysics and structural biology at present, and Frank is arguably the most distinguished practitioner of this art. CryoEM is likely over the next few years to take over much of the structural approaches currently requiring X-ray crystallography, because one can now get good and finely detailed images of single molecules down to as little as 200,000 MW, covering a substantial share of the molecules of greatest biomedical research interest. This book, the successor to an earlier work published in 1996 with Academic Press, is a natural companion work to our forthcoming book on electron crystallography by Robert Glaeser, with contributions by six others, including Frank. A growing number of workers will employ CryoEM for structural studies in their own research, and a large proportion of biomedical researchers will have a growing interest in understanding what the capabilities and limits of this approachTable of Contents1: Introduction 2: Electron Microscopy of Macromolecular Assemblies 3: Two-Dimensional Averaging Techniques 4: Multivariate Data Analysis and Classification of Images 5: Three-Dimensional Reconstruction 6: Interpretation of Three-Dimensional Images of Macromolecules Appendix 1: Some Important Definitions and Theorems Appendix 2: Profiles, Point-Spread Functions, and Effects of Commonly Used Low-Pass Filters Appendix 2: Bibliography of Methods Appendix 2: Bibliography of Structures Appendix 2: Special Journal Issues on Image Processing Techniques
£155.00
Oxford University Press Sensory Transduction
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£110.00
Oxford University Press The Neuron Cell and Molecular Biology
Book SynopsisThe Fourth Edition of The Neuron features newly updated chapters and scores of full-color figures, making it an ideal first course in the cell and molecular biology of nerve cells.Trade ReviewThe text is impressively modern, with up-to date information on the trendiest areas of neurobiology . . .the book is highly visual, with figures on virtually every page. The figures deserve special comment because they are a teacher's dream: simple and uncluttered, but conceptually powerful. Frankly, although the recommendation is often absurd, The Neuron is one of those books that really does belong on every shelf. * Nature *The format of each chapter is ideally suited for easy, enjoyable, and almost effortless learning . . . This is a superbly written and well-illustrated text covering all of the major aspects of neuroscientific knowledge . . . every neuroscientist should keep a copy handy. * Journal of Psychiatry and Neuroscience *This is a first-rate textbook for a course in cellular neurobiology for upper-level university students. My colleagues and I took it out on a shakedown cruise with a class of 250 undergraduates. The wind really caught their sails, and we sped quickly through it in the ten weeks of the academic quarter. The students appreciated the consistent clarity and the uniformity of style. The illustrations are highly conceptual and were easily understood . . . The up-to-date presentation of many exciting recent findings is a great strength. General principles are illustrated with a useful blend of data from vertebrate and invertebrate systems. * William S Messer, Jr., in The Quarterly Review of Biology *An outstanding, easily readable, and quite up-to-date overview of fundamental neurobiology. * Canadian Journal of Neurological Sciences *Table of ContentsPreface to the Fourth Edition ; I. Introduction ; 1. Signaling in the Brain ; 2. Form and Function in Cells of the Brain ; II. Electrical Properties of Neurons ; 3. Electrical Signaling in Neurons ; 4. Membrane Ion Channels and Ion Currents ; 5. Ion Channels Are Membrane Proteins ; 6. Ion Channels, Membrane Ion Currents, and the Action Potential ; 7. Diversity in the Structure and Function of Ion Channels ; III. Intercellular Communication ; 8. Intercellular Communication: How Neurons Communicate: Gap Junctions and Neurosecretion ; 9. Synaptic Release of Neurotransmitters ; 10. Neurotransmitters and Neurohormones ; 11. Receptors and Transduction Mechanisms I: Receptors Coupled Directly to Ion Channels ; 12. Receptors and Transduction Mechanisms II: Indirectly Coupled Receptor/Ion Channel Systems ; 13. Sensory Receptors ; IV. Behavior and Plasticity ; 14. The Birth and Death of a Neuron ; 15. Neuronal Growth and Trophic Factors ; 16. Adhesion Molecules and Axon Pathfinding ; 17. Formation, Maintenance, and Plasticity of Chemical Synapses ; 18. Intrinsic Neuronal Properties, Neural Networks and Behavior ; 19. Learning and Memory
£102.00
Penguin Random House LLC Cellular Biophysics Transport Volume 1 A Bradford Book
£73.81
Springer Water and Ions in Biological Systems
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£170.99
Springer Subcellular Biochemistry 11
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£123.49
Springer Molecular Mechanisms of Membrane Fusion
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£123.49
Springer Heparin and Related Polysaccharides 313 Advances in Experimental Medicine and Biology
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£170.99
Springer Current Directions in InsulinLike Growth Factor Research Proceedings of the Fourth International Symposium on Insulin IGFs and Their Receptors ... in Experimental Medicine and Biology
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£115.50
Springer Bioelectrochemistry IV
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£109.50
Springer Chemicals via Higher Plant Bioengineering
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£123.49
Springer Bacterial Invasion into Eukaryotic Cells
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£237.49
Springer Fusion of Biological Membranes and Related Problems Subcellular Biochemistry 34
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£170.99
Springer The Genetic Code and the Origin of Life Molecular Biology Intelligence Unit
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£123.49
Springer Molecular Mechanisms of Werner S Syndrome Medical Intelligence Unit Unnumbered
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£85.49
Springer Functional Tissue Engineering
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£123.49
Springer Cell Surface Receptors
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£123.49
Springer Cell Volume and Signaling
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£85.49
Springer Synaptic Plasticity and Transsynaptic Signaling
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£179.99
Springer Mechanisms of Lymphocyte Activation and Immune Regulation X
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£123.49
Springer Biochemistry of Atherosclerosis
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£170.99
Springer Cardiac Mechanotransduction Medical Intelligence Unit Medical Intelligence Unit Unnumbered
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£132.28
Springer The Kinetochore
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£85.49
Springer Advances in Molecular Oncology
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£170.99
Springer TNF Receptor Associated Factors TRAFs
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£85.49
Springer Lysosomal Storage Disorders
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£197.99
Springer Foundations of Systematics and Biogeography
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£170.99
Springer Biological LowVoltage Scanning Electron Microscopy
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£123.49
Springer Eukaryotic Membranes and Cytoskeleton
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£123.49
Springer The Golgi Apparatus
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£152.99
