Biology, life sciences Books
Johns Hopkins University Press The Secret Perfume of Birds
Book SynopsisThe untold story of a stunning discovery: not only can birds smell, but their scents may be the secret to understanding their world. Winner of the PROSE Award for Best Book in Popular Science and MathematicsThe puzzling lack of evidence for the peculiar but widespread belief that birds have no sense of smell irked evolutionary biologist Danielle Whittaker. Exploring the science behind the myth led her on an unexpected quest investigating mysteries from how juncos win a fight to why cowbirds smell like cookies. In The Secret Perfume of Birdspart science, part intellectual history, and part memoirWhittaker blends humor, clear writing, and a compelling narrative to describe how scent is important not just for birds but for all animals, including humans. Whittaker engagingly describes how emerging research has uncovered birds' ability to produce complex chemical signals that influence their behavior, including where they build nests, when they pick a fight, and why they fly away. Mate Trade ReviewFrom tangerine-scented auklets to mossy-smelling juncos, birds are more fragrant than you might think.—Simon Ings, NEW SCIENTISTWhittaker blends science writing and memoir to explore how birds make use of odors in her delightful debut. Whittaker's a natural explainer, and her willingness to poke fun at herself only enhances her fascinating account. Fans of Jon Dunn and Jonathan Meiburg will be charmed.—Publishers WeeklyA delightfully meandering account...Whittaker presents a new lens for bird lovers to view common species, and she had me wondering what some of my favorite birds smell like... The book's greatest success is how it depicts the reality of doing science...It takes a diverse group of perspectives—and the humility to reconsider our biases—to truly understand our world.—Ryan Mandelbum, Scientific AmericanWhittaker's wide-ranging book combines memoir, intellectual history, and the results of her own scientific research on avian chemical communication, which challenges the long-held belief in ornithology that birds don't have a sense of smell. Whittaker also discusses her unorthodox academic career and her personal life (including her roller derby alter ego 'Chunk Rock Girl'), adding zest to the science.—Library JournalBeautifully written.—BirdWatchingFull of vivid descriptions of fieldwork adventures, fun facts about bird scents, detailed scientific explanations that always stay very readable....A charming and readable background to a little-studied area of ornithology.—BTO News (British Trust for Ornithology)Whittaker convincingly busts the myth of avian anosmia....[The Secret Perfume of Birds]rewards the reader with fascinating insights into the fields of animal behaviour and chemical communication.—The Inquisitive BiologistTable of ContentsPreface. Follow Your NoseChapter 1. The Most Ancient and Fundamental SenseChapter 2. Following the Bird's NoseChapter 3. Deciphering the Secrets of SmellsChapter 4. What Does Sexy Smell Like?Chapter 5. Making Scents of BacteriaChapter 6. Thanks for SharingChapter 7. MHC: Magical Happiness Controller?Chapter 8. Girl PowerAfterword. A Breath of Fresh AirAcknowledgmentsGlossaryReferencesIndex
£21.85
Johns Hopkins University Press Cave Biodiversity
Book SynopsisA deep-dive into the evolutionary biology, biogeography, and conservation of the most elusive subterranean creatures in the world. Far from the austere, sparsely populated ecosystems often conjured in the imagination, caves host some of the most mysterious and biodiverse natural systems in the world. Subterranean environments, however, are the least explored terrestrial habitats, contributing to misconceptions about their inhabitants. Edited by cave scientist and conservation ecologist Dr. J. Judson Wynne, Cave Biodiversity explores both the evolution and the conservation of subterrestrial-dwelling fauna. Covering both vertebrates and invertebrates, including mollusks, fishes, amphibians, arthropods, and other troglobionts, this volume brings together ichthyologists, entomologists, ecologists, herpetologists, and conservationists to provide a nuanced picture of life beneath the earth's surface. Broad chapters covering biotic and abiotic factors that influence evolution and support biTable of ContentsList of ContributorsForewordPrefaceAcknowledgementsChapter 1. Influence of the Physical Environment on Terrestrial Cave DiversityChapter 2. Evolutionary Models Influencing Subterranean SpeciationChapter 3. Biology and Ecology of Subterranean MolluscaChapter 4. The Subterranean Cholevinae of ItalyChapter 5. Cave Trechine (Coleoptera: Carabidae) Radiation and Biogeography in Eastern North America,Chapter 6. Subterranean Colonization and Diversification of Cave-dwelling SalamandersChapter 7. Diversity, Distribution, and Conservation of Cavefishes in ChinaIndex
£67.15
Johns Hopkins University Press Frogs of the United States and Canada
Book SynopsisThe most thorough, updated guide to frogs and toads in the United States and Canada available. A stunning diversity of frog species can be found from coastal swamps to lofty mountain peaks, and from the Florida Keys to the Arctic Ocean. They live in subtropical lowlands, grassland prairies, deserts, and alpine-tundra habitats. Some species have restricted habitat requirements, whereas others occur contiguously from the arid plains or humid southeastern forests to the high tundra. In this new edition of Frogs of the United States and Canada, C. Kenneth Dodd Jr. tours the reader through the marvelous world of North American frogs. Covering 114 native and introduced species from all US states and Canadian provinces, this comprehensive reference on the biology, behavior, and conservation of the Order Anura includes detailed and updated information on past and present distribution life history and demography reproduction and diet landscape ecology and evolution diseases, parasites, and
£140.25
Johns Hopkins University Press Sexual Segregation in Ungulates
Book SynopsisWhy does it benefit some male and female animals to live separately?Winner of the Wildlife Society Publication Best Authored Book Award by The Wildlife SocietySexual segregation, wherein the sexes of a species live apart for long periods of time, has far-reaching consequences for the ecology, behavior, and conservation of hooved mammals, which are called ungulates. Award-winning researcher R. Terry Bowyer has spent the past four decades unravelling the causes and consequences of this perplexing phenomenon by studying ungulates and the large carnivores that prey upon them. In Sexual Segregation in Ungulates, Bowyer's critical, thought-provoking approach helps resolve long-standing disagreements concerning sexual segregation and offers future pathways for species and habitat conservation. He highlights important elements of the natural history of wild ungulate species, including bighorn sheep and elk. He then uses this perspective to frame and test hypotheses illuminating the motivationsTable of ContentsPreface Acknowledgments Chapter 1. Introduction and Overview Historical Perspectives Ungulate Characteristics and Relevant Aspects of Their Behavior, Ecology, and Conservation Mating Systems Predator Pits, Apparent Competition, and Territorial Regulation of Populations Sexual Segregation in Plants and Animals Chapter 2. Differences between the Sexes Definitions of Sexual Segregation Sexual Differences in Morphology, Physiology, and Foraging Behavior Sexual Dimorphism The Role of Resources and Predation Risk in Gregariousness Chapter 3. Temporospatial Patterns Defining Social Groups Temporal Patterns of Sexual Segregation and Aggregation Spatial Patterns of Sexual Segregation Chapter 4. Detection and Measurement Detecting Sexual Segregation Measuring Sexual Segregation Effects of Scale Chapter 5. Failed Concepts Setting Aside Rejected Hypotheses Social Hypotheses Ecological Hypotheses Limiting Overutilization of Habitats Chapter 6. The Role of Social Behavior Social Aggression and Sexual Affinities Activity Patterns The Social-Constraints Hypothesis Chapter 7. Ecological Aspects of Sexual Segregation Competition Hypothesis Gastrocentric Hypothesis Niche-Partitioning Hypothesis Predation-Risk Hypothesis Multiple Causations and Tradeoffs Chapter 8. Consequences of Sexual Segregation for Theory and Management Paternal Investment and Sexual Selection Population Dynamics Chapter 9. Failing to Consider Sexual Segregation Moose North American Elk White-Tailed Deer Bighorn Sheep Chapter 10. The Future Defining Sexual Segregation Why Is Sexual Segregation Overlooked? Future Questions and Directions Relevance to Other OrganismsLiterature CitedIndex
£52.70
Johns Hopkins University Press Scientific Collaboration
Book SynopsisA narrative guide to help scientists improve their collaboration techniques and build trusting relationships with their research teams. The days of scientists conducting solitary inquiries in isolated labs are effectively over, with most researchers instead collaborating in cross-functional teams. In addition to mastering the technical skills necessary in their respective fields, scientists must now learn strategies for better communication and relationship building to succeed in reaching their research goals. In Scientific Collaboration, biosecurity researcher and animal disease ecologist Jeanne M. Fair shares excitingand occasionally cringeworthytrue stories of scientists working together. These examples provide an approachable way to introduce the principles crucial to effective scientific collaboration. From the global community of scientists measuring sea-ice decline to cooperative private-public sector investigations of harrowing virus outbreaks, the experiences described demTable of ContentsAcknowledgmentsIntroductionChapter 1. Transformative CollaborationsChapter 2. CommunitiesChapter 3. A Scientific RevolutionChapter 4. The Science of Team ScienceChapter 5. TrustChapter 6. CompetenceChapter 7. CommunicationChapter 8. Fish Don't Know They're in WaterChapter 9. Dream TeamsChapter 10. Science NetworksChapter 11. What the Hell just Happened?ReferencesIndex
£42.50
Johns Hopkins University Press Before They Vanish
Book Synopsis
£22.50
Taylor & Francis Inc Histochemical and Cytochemical Methods of
Book SynopsisHistochemistry and cytochemistry are important fields for studying the inner workings of cells and tissues of the body. While visualization techniques have been in use for many years, new methods of detection developed recently help researchers and practitioners better understand cell activity. Histochemical and Cytochemical Methods of Visualization describes the essential techniques that can be used for histochemical investigations in both light and transmission electron microscopy. The book begins by discussing techniques in light microscopy. It reviews classical methods of visualization, histochemical and histoenzymatic methods, and methods used to visualize cell proliferation and apoptosis. Next, the book examines the cytochemical methods used in electron microscopy with traditional techniques, as well as more specialized methods. The final section provides an overview of image analysis and describes how image processing methods can be used to extract vital Table of ContentsHistological and Histochemical Methods with Light Microscopy. Classical Methods of Visualization. Histochemical Methods. Enzyme Histochemistry Methods. Visualization of Cell Proliferation. Visualization of Apoptosis. High-Speed Tissue Proteomic. Preparation of Products for Histology and Histochemistry. Cytological Methods in Electron Microscopy. General Techniques in Electron Microscopy. Cytochemical Techniques. Ultrastructural Cytoenzymology. The Acetylation Method. Preparation of Products for Electron Microscopy. Image Quantification. Image Quantification in Histology and Cytology. Index.
£215.00
Taylor & Francis Inc Molecular Cellular and Tissue Engineering
Book SynopsisKnown as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine.More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, Table of ContentsMOLECULAR BIOLOGY. TRANSPORT PHENOMENA AND BIOMIMETIC SYSTEMS. PHYSIOLOGICAL MODELING, SIMULATION, AND CONTROL. STEM CELL ENGINEERING: AN INTRODUCTION. TISSUE ENGINEERING ARTIFICIAL ORGANS. DRUG DESIGN, DELIVERY SYSTEMS, AND DEVICES PERSONALIZED MEDICINE. ETHICS.
£185.00
Taylor & Francis Inc Nutrition Lifestyle Factors and Blood Pressure
Book SynopsisEven though enormous advancements have been made in identifying evidence-based lifestyle strategies for hypertension prevention and management, little progress has been made in implementing these proven strategies. Nutrition, Lifestyle Factors, and Blood Pressure compiles practical, science-based information for health care providers to provide effective lifestyle interventions for blood pressure care. Divided into three sections, the book features: Evidence-based blood pressure control and relevant considerations for real-life situations Special considerations in blood pressure control and lifestyle modification among children and adolescents, during pregnancy, and among those with diabetes Practical tools that health care providers can put into practice in particular settings An excellent supplement to existing resources, Nutrition, Lifestyle Factors, and Blood Pressure shortensTable of ContentsEvidence Behind Lifestyle Factors and Blood Pressure. Behavioral Strategies and Blood Pressure Control. Special Considerations.
£175.00
Taylor & Francis Inc Chemical Genomics and Proteomics
Book SynopsisSince the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous novel methods and subdisciplines, such as chemical glycomics and lipidomics. This second edition has been updated to uniquely reflect this interdisciplinary feature as well as the remarkable developments that have occurred. The new edition also covers innovative applications from cell biology to drug discovery to, more recently, clinical diagnostics and medical practice, which utilize the concepts of chemical genomics.The text provides an overview of the strategies and methodologies of chemical genomics, focusing on emerging technologies and recent applications in the areas of combination chemical genetics, toxicogenomics, drug chemical genomics and proteomics, and orthogonal chemical genetics. It describes the development and application of novel analytical methods used in lTrade ReviewPraise for the First Edition"I thoroughly enjoyed this book and have already had to retrieve it from my PhD students who are anxious to read it ...make sure your library has a copy!"—Journal of Chemical Technology and Biotechnology, Vol. 80, Issue 8, August 2005"[This book] is the first book dedicated solely to chemical genomics. It presents the most important research and developments in chemical genomics … The plentiful tables and figures are well-designed and effectively support the content. … highly recommended for academic and special libraries with relevant programs, and for research scientists in the field."—E-StreamsTable of ContentsUtilizing small molecules in chemical genomics: Toward high-throughput approaches. Development and application of novel analytical methods in lipidomics. From chemical genomics to chemical proteomics: The power of microarray technology. Genomic and proteomic biomarkers in the drug R&D process. Quo vadis biomedical sciences in the omics era: Toward computational biology and medicine. Novel chemogenomic approaches to drug design.
£175.75
Taylor & Francis Inc OMICs Technologies
Book SynopsisSince the completion of the Human Genome Project, food and nutrition sciences have undergone a fundamental molecular transformation. New discoveries in molecular biology, analytical chemistry, and biochemistry have led to the development of new tools that are likely to revolutionize the study of food. OMICS Technologies: Tools for Food Science explores how these tools reveal the fundamental pathways and biochemical processes that drive food and nutrition sciences.In this volume, an international panel of researchers examines the rise of these new technologiesincluding metabolomics, metagenomics, nutrigenomics, transcriptomics, and proteomicsand describes how they translate to food science research and productive technologies. The book explains how these methods can be used to assess the quality attributes of foods and food production systems. It explores the principles that regulate food production, analyzes processing and ethical issues, and documentsTable of ContentsNutrition Science and "Omics" Technologies: Ethical Aspects in Global Health. Array Platform for Food Safety and Quality. Metabolomics and Food Science: Concepts and Serviceability in Plant Foods and Nutrition. Foodomics: A New Omics for a New Food Era. Proteomics in Food Biotechnology. Challenges in Feasible Problem Construction in Nutritional Genomics: An Empirical Study. Genomics and Breeding in Food Crops. Genomics of Fruit Quality and Disorders. Systems Biology Approaches Reveal New Insights into the Molecular Mechanisms Regulating Flesh Fruit Quality. Coffee Genomics. Omics Approaches to Meat Quality Management. Functional Genomics to Improve Meat Quality in Pigs. Meat Science and Proteomics. Wine-Omics: New Platforms for the Improvement of Yeast Strains and Wine Quality. Aspergillus flavus Genetics and Genomics in Solving Mycotoxin Contamination of Food and Feed. Index.
£209.00
Taylor & Francis Inc Diet Exercise and Chronic Disease
Book SynopsisExercise and diet are key factors in the etiology and prevention of chronic disease. While most books on chronic disease have a decided clinical approach, Diet, Exercise, and Chronic Disease: The Biological Basis of Prevention brings together the latest cellular- and molecular-based research on the etiology of chronic diseases and the impact of various aspects of diet and exercise on the causal mechanisms. By focusing on cellular biology, details of the integrative nature of the many different underlying factors are revealeddetails that are not evident with the prevailing clinical approach to chronic disease.This book highlights chronic diseases that are major causes of mortality, and which have sufficient molecular evidence for dietary and activity-related components to their etiology. Individual chapters examine the role of diet and exercise in diabetes, atherosclerosis, osteoporosis, cancer, and neurodegenerative disease. They cover aspects such as disease etiologyTable of ContentsIntroduction. Inflammation. Diabetes. Atherosclerosis. Osteoporosis. Cancer. Neurodegenerative Disease. Hunger and Satiety Signaling. Summary and Recommendations. Index.
£175.00
Taylor & Francis Inc Handbook of Disease Causing Microbes
Book SynopsisThe Book provides knowledge on the diversity of disease causing microbes including bacteria, viruses, fungi and Protozoans- the major diseases they cause and the environmental factors that influence the occurrence, transmission and spread of microbes along with the epidemiological factors determining the occurrence of disease.
£120.00
Taylor & Francis Inc Bacterial NanoCellulose
Book SynopsisBacterial nanocellulose (BNC) is an emerging nanomaterial with unique properties produced by several species of ubiquitous fermentation bacteria, most importantly Gluconacetobacter xylinus, previously known as Acetobacter xylinum. BNC has been used for a variety of commercial applications including textiles, cosmetics, and food products, and it has a high potential for medical applications. Bacterial NanoCellulose: A Sophisticated Multifunctional Material provides the state of the art of scientific knowledge about the mechanism of cellulose production by bacteria along with pointing out challenges in expansion of BNC production in large scale. It provides the latest update on BNC structure and its modification, as well as comprehensive information about current and future applications of BNC. This seminal work covers the basic science, technology, and economic impact of this bulk chemical as well as the companies and patents that are driving the field. ItTable of ContentsBiosynthesis of Bacterial Cellulose. Effect of Cultivation Conditions on the Structure and Morphological Properties of BNC Biomaterials with a Focus on Vascular Grafts. Large-Scale Production of BNC: State and Challenges. Tough Bacterial Nanocellulose Hydrogels Based on the Double-Network Technique. Bacterial Cellulose Surface Modifications. Nematic Ordered Cellulose Templates. Applications and Products—Nata de Coco. Wound Dressings and Cosmetic Materials from Bacterial Nanocellulose. Bacterial Nanocellulose Hydrogels Designed as Bioartificial Medical Implants. Bacterial Nanocellulose Biomaterials with Controlled Architecture for Tissue Engineering Scaffolds and Customizable Implants. Biomimetic Mineralization of Apatite on Bacterial Cellulose. Bacterial Nanocellulose as a Structured Platform for Conductive Biopolymers.
£150.00
Taylor & Francis Inc Managing Your Biological Data with Python
Book SynopsisTake Control of Your Data and Use Python with ConfidenceRequiring no prior programming experience, Managing Your Biological Data with Python empowers biologists and other life scientists to work with biological data on their own using the Python language. The book teaches them not only how to program but also how to manage their data. It shows how to read data from files in different formats, analyze and manipulate the data, and write the results to a file or computer screen. The first part of the text introduces the Python language and teaches readers how to write their first programs. The second part presents the basic elements of the language, enabling readers to write small programs independently. The third part explains how to create bigger programs using techniques to write well-organized, efficient, and error-free code. The fourth part on data visualization shows how to plot data and draw a figure for an article or slide pTrade Review“… a significant step forward … The book is cleverly designed to cover a wide range of subjects in a pleasant, easy-to-follow sequence of chapters. These have been carefully prepared so that the minimum level of interdependence is kept, making it possible to begin working at virtually any level without falling into intricate cross-references. A beginner will find the first chapters quite welcoming while a person with medium or even high levels of programming experience can easily find a suitable entry point in the middle.The book is written using an entertaining style that pushes the reader into a naturally built engaging experience … the authors have chosen a collection of underlying subject areas that cover a very wide variety of interests, ensuring that mixed audiences are kept engaged. In that sense, the content becomes adaptable to the wide diversity of learners that are found in today's communities of specialised biologists.… also usable as a reference guide, due to the richness of its worked examples that will prove valuable as seeds for code development for programmers at any level. … as a single book to support learning Python for problem solvers in the life sciences, this book is certainly a very smart choice. It is also ready for creative teachers to develop more in the same direction.”—Pedro L. Fernandes, Instituto Gulbenkian de Ciência"Having read Managing Your Biological Data with Python brings back memories of the times I started writing my first lines of code nearly a decade ago. As a beginning structural biologist without any coding experience, this book would have been a welcome companion to quickly get me started on my bioinformatical projects with Python. It is this, often pragmatic, attitude scientists have towards programming that makes Python the language of choice for many. A clear syntax, powerful build-in functions and a lively ecosystem of user contributed modules allow you to do advanced things with only little lines of code. The book introduces you to the basic principles of programming in Python using the many build-in functions. It does so using practical examples that you can start using right away in your day-to-day research.Python’s modular design principles could even be seen in the organization of this book. If you have never written a line of code in your life, the first chapters are indispensable to teach you basic coding principles but if you have some experience, you can safely skip these. I would however, recommend to read the ones introducing the build-in functions. It never hurts to refresh your memory on the many powerful build-ins Python actually has; I certainly forgot about one or two of them. Working your way through the first chapters will help you get comfortable with Python and lay the foundation for writing more advanced programs in the remaining chapters. These chapters introduce some of the powerful community contributed Python modules that make your life as a biologist a whole lot easier. Again, the example code introducing these modules is of high practical value and together with the coding recipes in the ‘cookbook’ chapter they provide a solid blueprint for you to build your own code upon. I’m confident that reading Managing Your Biological Data with Python will quickly allow you to get the most out of your data and start answering those trilling scientific questions you have, and do all of that while having fun. "—Marc van Dijk, Structural biologist, bioinformaticien, and eScience entrepreneur, Bijvoet Center for Biomolecular Research, Utrecht University, The Netherlands"For many biologists faced with computational challenges, Python has become the language of choice, due to its power, elegance, and simplicity. Managing Your Biological Data with Python by Allegra Via et al. teaches Python using biological examples and discusses important Python-driven applications, such as PyMol and Biopython. The book is an excellent resource for any biologist needing relevant programming skills."—Thomas Hamelryck, Associate Professor, Bioinformatics Center, University of Copenhagen, Denmark"Biological data volumes are growing rapidly as high-throughput technologies (e.g., DNA microarrays or DNA/RNA sequencing) improve. Managing and analyzing biological data are becoming more demanding and the application of programming techniques has simply become a standard. Managing Your Biological Data with Python is one of very few user-friendly books for biologists. It is amazing how clearly authors explain the possible applications of Python for data management (parsing data records, filtering and sorting data) and data visualization (also using the Python interface to R). The book also offers the description of modular programming, which is simply excellent! It guides readers from writing simple functions through writing classes to building program pipelines—everything according to Python coding standards and in an easy-to-follow way. This is absolutely the best book to start learning Python. Intermediate Python users can use this book to learn some new tricks that they could implement in their own code. I can highly recommend this book to researchers, students, and their lecturers."—Dr. Barbara Uszczynska, Centre de Regulació Genòmica (CRG), Barcelona, SpainTable of ContentsGetting Started: The Python Shell. Your First Python Program. Data Management: Analyzing a Data Column. Parsing Data Records. Searching Data. Filtering Data. Managing Tabular Data. Sorting Data. Pattern Matching and Text Mining. Modular Programming: Divide a Program into Functions. Managing Complexity with Classes. Debugging. Using External Modules: The Python Interface to R. Building Program Pipelines. Writing Good Programs. Data Visualization: Creating Scientific Diagrams. Creating Molecule Images with PyMOL. Manipulating Images. Biopython: Working with Sequence Data. Retrieving Data from Web Resources. Working with 3D Structure Data. Cookbook. Appendices.
£62.99
Taylor & Francis Inc Materials in Biology and Medicine
Book SynopsisWhile the interdisciplinary field of materials science and engineering is relatively new, remarkable developments in materials have emerged for biological and medical applications, from biocompatible polymers in medical devices to the use of carbon nanotubes as drug delivery vehicles. Exploring these materials and applications, Materials in Biology and Medicine presents the background and real-world examples of advanced materials in biomedical engineering, biology, and medicine.With peer-reviewed chapters written by a select group of academic and industry experts, the book focuses on biomaterials and bioinspired materials, functional and responsive materials, controlling biology with materials, and the development of devices and enabling technologies. It fully describes the relevant scientific background and thoroughly discusses the logical sequences of new development and applications.Presenting a consistent scientific treatment of all tTrade Review" … a timely addition to the field … Cutting-edge articles by leading experts review critical areas covering biomaterials and biomimetic materials, materials function and response modification, and medical device development. Each application-oriented chapter provides the relevant scientific and engineering background with extensive references for further study and research. The contributors use multiple examples to provide rich insights into a broad array of biomaterial applications for a target audience consisting of graduate students, materials scientists, research engineers, and academic physicians and surgeons."—Dr. Sunil K. Kesavan, Akebono Inc., Farmington Hills, Michigan, USA"… a timely addition to the field of … Cutting-edge articles by leading experts review critical areas covering biomaterials and biomimetic materials, materials function and response modification, and medical device development. Each application-oriented chapter provides the relevant scientific and engineering background with extensive references for further study and research. The contributors use multiple examples to provide rich insights into a broad array of biomaterial applications for a target audience consisting of graduate students, materials scientists, research engineers, and academic physicians and surgeons." —Dr. Sunil K. Kesavan, Akebono Inc., Farmington Hills, Michigan, USATable of ContentsIntroduction: Materials in Biology and Medicine. Biomaterials. Hydrophilic Polymers for Biomedical Applications. Hydrogels. Polyanhydrides. Functional Biomaterials. Molecularly Imprinted Polymers. Functionalization of Carbon Nanotubes. Animal Cell Culture. Tissue Engineering. Bioactive Devices. Cell Encapsulation. BioMEMS. Immobilized Enzyme Technology. Biocompatibility-Imparting Nanofilm Coating.
£237.50
Taylor & Francis Ltd Guide to Health Informatics
Book SynopsisHighly recommended by JAMA, this essential textbooks provides a comprehensive yet accessible overview of the basic concepts of information and communication technologies in healthcare.Trade Review"Comprehensive. Timely. Readable. Interesting. Useful as a textbook and/or reference. Relevant. Highly recommended... It is this reviewer’s opinion that this text is useful as a textbook and/or reference. It could easily serve the purpose as a textbook for an undergraduate biomedical engineering elective course, followed by, if possible, a course in database development. The text is highly relevant to engineers working in medicine, and is thus highly recommended." – Paul. H. King, Ph.D., P.E, Vanderbilt University, IEEE Pulse"...should be required reading for every physician intending to enter a fellowship program in medical informatics, and it is also highly recommended to every doctor and medical student interested in this emerging medical specialty."—JAMA"A simply brilliant introduction to this fast developing field which is comprehensive, up to date, and at the same time sophisticated... It should be read by all healthcare professionals."—2004 BMA Book Awards Judging PanelTable of ContentsBasic Concepts in Informatics. Informatics Skills. Information Systems in Healthcare. Guideline- and Protocol-Based Systems. Communication Systems in Healthcare. Language, Coding and Classification. Clinical Decision Support and Analytics. Specialized Applications for Health Informatics.
£62.99
John Wiley and Sons Ltd Biological Oceanography
Book SynopsisThis new edition of Biological Oceanography has been greatly updated and expanded since its initial publication in 2004. It presents current understanding of ocean ecology emphasizing the character of marine organisms from viruses to fish and worms, together with their significance to their habitats and to each other. The book initially emphasizes pelagic organisms and processes, but benthos, hydrothermal vents, climate-change effects, and fisheries all receive attention. The chapter on oceanic biomes has been greatly expanded and a new chapter reviewing approaches to pelagic food webs has been added. Throughout, the book has been revised to account for recent advances in this rapidly changing field. The increased importance of molecular genetic data across the field is evident in most of the chapters. As with the previous edition, the book is primarily written for senior undergraduate and graduate students of ocean ecology and professional marine ecologists.Trade Review“Due to its comprehensive nature, it is clear that this book will also succeed as a standard text for use in undergraduate and graduate marine science courses.” (Austral Ecology, 10 October 2014) “Overall I found it to be an immensely informative and entertaining read. This book will make an excellent core text for any graduate level course in Biological Oceanography whether introductory or advanced...I also think that every Biological Oceanographer should read it. It is an enlightening experience to view your field through the eyes of two colleagues who have been in this business for a long time. I also found reading this book a humbling experience. Charlie Miller and Pat Wheeler demonstrate an amazing depth and diversity of understanding in almost every topic that is taken up. I hope by the time I get to where they are in their careers I have achieved this level of scholarship in Biological Oceanography.” (Limnology and Oceanography Bulletin, 1 May 2013) “The book is extremely well referenced for further study and the impression is that most of the work cited is from within about the last twenty years. Altogether a worthy addition to any marine departmental library.” (British Ecological Society Bulletin, 1 December 2012)Table of ContentsPreface to the second edition vii Acknowledgements viii 1 Ocean ecology: some fundamental aspects 1 2 The phycology of phytoplankton 19 3 Habitat determinants of primary production in the sea 49 4 Numerical models: the standard form of theory in pelagic ecology 73 5 A sea of microbes: archaea, bacteria, protists, and viruses in the marine pelagial 96 6 The zoology of zooplankton 115 7 Production ecology of marine zooplankton 130 8 Population biology of zooplankton 158 9 Pelagic food webs 181 10 Biogeography of pelagic habitats 202 11 Biome and province analysis of the oceans 230 12 Adaptive complexes of meso- and bathypelagic organisms 276 13 The fauna of deep-sea sediments 292 14 Some benthic community ecology 321 15 Submarine hydrothermal vents 351 16 Ocean ecology and global climate change 367 17 Fisheries oceanography 396 References 427 Index 459
£53.15
John Wiley and Sons Ltd Dunes
Book SynopsisDunes is the first book in over a decade to incorporate the latest research in this active and fast-developing field. It discusses the shapes, sizes, patterns, distribution, history and care of wind-blown dunes, and covers all aspects of dunes, terrestrial and in the Solar System. The only book to cover all dunes, terrestrial and in the Solar System, in deserts, on coasts, and in the past Represents the most current update on the research of dunes for over a decade Incorporates the latest research to come out of China where the field is most rapidly expanding Discusses the most recent range of skills and technology now focused on the study of dunes Brings up-to-date a rapidly expanding field Trade Review “This is a terrific read for both specialists and nonspecialists. Summing Up: Highly recommended. Upper-division undergraduates through professionals/practitioners.” (Choice, 1 February 2014)Table of ContentsList of Figures xi Acknowledgements xv Introduction 1 Part One <10 m2; <10 years 5 1 Wind and Sand 7 Wind versus Bed 7 The Law of the Wall 8 Improving the wind/bed model 9 Lift-Off 12 Holding down by gravity 12 Holding down by cohesion 12 Raising by lift 13 Raising by drag 13 Raising by bombardment 14 Thresholds 14 Grain size 16 The slope of the bed 17 The dynamics of water content 17 Crusts 19 Pellets 20 Sand in Motion 20 Saltation 20 Streamers and other medium-scale patterns of saltating sand 22 Reptation 22 Creep 23 Other near-surface activity 23 Suspension 24 The vertical distribution of load and grain size 24 The saturation length 24 The fetch effect 26 The response of a loose bed to erosion by the wind 27 The Transport Rate 27 Shapes, densities and mixtures of size 29 Hard surfaces 30 Rough surfaces 30 Moisture, temperature and humidity 31 Rain 31 References 31 2 Ripples 32 Subtypes 35 Models 36 Flow response 36 Gravity wave 36 Saltation length 37 Shadow zone 37 Mathematical 37 Pattern 38 3 The Form and Behaviour of Free Dunes 39 Definitions 39 Early Stages 39 Start 39 Minimum size 40 The Profile of a Fully Grown Dune 41 Toe 41 Windward slope (or ‘stoss slope’) 43 Crest 45 Lee slope 46 Movement 53 Turnover time, bulk transport 56 Size 56 Flow-hierarchy models 57 Grain-size models 57 The time/supply model 58 References 58 Part Two 1000 to 10,000 m2; 100 to 1000 years 59 4 Pattern in Free Dunes 61 Definitions 61 Wind-Directional Regimes 62 Global winds 62 Local wind systems 62 The Classification of Wind-Directional Regimes 65 Wind-Directional Regimes and Dune Pattern 66 Transverse Dunes 66 Two-dimensional pattern: vertical and downwind 67 Two-dimensional pattern: horizontal and transverse to the wind 68 Self-organisation 69 Barchans 71 Quasi-transverse patterns 75 Linear Dunes 80 Introduction 80 Models of formation 82 Sand Sheets 88 Dunes with Distinctive Sand 90 Gravel dunes 90 Zibars 91 Clay dunes 92 Lunettes 92 Gypsum dunes 93 Diatomite sands 93 Volcanic sands 93 Snow and ice dunes 94 Niveo-aeolian deposits 94 References 94 5 Forced Dunes 96 Dunes Built around Bluff Obstacles 96 Climbing and echo dunes 96 Flanking and lee dunes 97 Cliff-top and falling dunes 99 Dunes on Gently Sloping Terrain 99 Reference 99 6 Dunes and Plants 100 Wind, Sand and Plants 100 Rigid objects 100 Spatial pattern 101 Porosity 102 Flexibility 102 Plants as living things 103 The broader time/space framework 104 Dunes among Plants 104 Nebkhas 104 Blowouts 107 Parabolic dunes 109 References 111 7 Coastal Dunes 112 Coastal Dunes and Climate 112 The Beach–Dune System 114 Exclusively Coastal Dunes 117 Embryo dunes 117 Fore-dunes (‘frontal dunes’ or ‘retention ridges’) 118 Tsunamis 120 Coastal sand sheets 120 References 121 Part Three >0.3 mm; <2,200,000,000 years 123 8 Sand Seas 125 Terms 125 Large Sand Seas 127 Growth and Development 127 Sand Seas in Tectonic Basins 129 Topographically Unconfined Sand Seas 131 Transfer between Sand Seas 133 9 A History of Dune Sand 134 Provenance 134 Recycling 137 Maturation 139 Mineralogy 139 Size characteristics 141 Shape and surface texture 141 Redness 144 Relationships between Dune Fields and the Sources of Their Sand 145 Source-bordering dune fields 145 Dune fields that have migrated away from their source 145 Sand seas that have taken sand from many local sources 146 The Australian sand seas and some aeolian sandstones 146 References 146 10 A History of Inland Dunes 147 Very Ancient Dunes: Siliceous Windblown Sandstones 147 The Emergence of Familiar Spatial and Dynamic Patterns 151 Dune Historiography 153 Dating 153 Dune-building environments 156 The long-term development of sand seas: sediment state 160 Quaternary Dune-Building Climates 160 Dunes in the Early- and Mid-Pleistocene 162 Late Pleistocene Dunes 163 The main theatres of dune formation in the Late Pleistocene 165 Dunes in the Holocene 175 The deglaciated North 176 The mid-latitudes 177 The semi-arid tropics 178 The present deserts 178 References 179 11 A History of Coastal Dunes 181 Long Sequences 181 Sea Level 181 Other Controls 182 Calcareous Aeolianite 184 Reference 185 12 Mars, Venus, Titan 186 Similarities 186 Differences 187 Sand 188 Ripples and Transverse Aeolian Ridges 190 Dunes 191 Mars 191 Venus 194 Titan 194 Reference 195 Part Four Care 197 13 Local, Short-Term Care (<1000 m2; <10 years) 199 Dunes in Deserts 199 Folk science 199 New approaches 200 Stabilised Dunes in Semi-Arid Areas 204 Coastal Dunes 204 References 207 14 Sustainability (>100,000 m2; >10 years) 208 Constraints 208 Complexity 208 Uncertainty 210 Environmental change 210 Sustainability 211 Coastal dunes 211 Stabilised inland dunes 212 References 213 Index 214
£54.00
Taylor & Francis Inc Atlas of Human Poisoning and Envenoming
Book SynopsisClinicians undergoing competency testing, certification, and periodic recertification are frequently faced with computer-based exams designed to evaluate clinical acumen and judgment. Test questions often include an image or radiograph followed by a vignette of the clinical encounter and a series of questions. Designed to better prepare practitioners for image-intense, computer-based examinations in their respective fields, Atlas of Human Poisoning and Envenoming is a visual and written reminder of the ubiquitous sources of toxins and toxoids in the environment and the outcomes of accidental or intentional toxic exposures in humans. The Second Edition has been restructured with bulleted text, tables, and figures resembling the vignettes that accompany national examinations. Combining the four specialties of toxicologyanalytical, medical, environmental, and industrialinto one comprehensive atlas, the book presents photographs and diagrams of toxic plants aTrade Review"Compared to other narrative-based references in this exceptionally complicated and detail-driven field, this atlas presents small bites of easily digestible information."—Sean P. Boley, MD, Regions Hospital and Level 1 Trauma Center for Doody's Review ServiceTable of ContentsGeneral Medical Toxicology. The Pharmacology of Human Poisoning and Envenoming. General Poisoning Management. Diagnostic Work-Up of the Poisoned Patient. Poison Antidotes. Toxicity of Antiseptics and Drug Additives. Poisonings with Over-the-Counter and Opioid Analgesics. Household Product Poisonings. Drug and Illicit Substance Abuse. Anticonvulsants and Sedative-Hypnotics. Reproductive and Perinatal Toxicology and Teratogenesis. Hypoglycemic and Other Endocrine Agent Toxicity. Cardiovascular Drug Toxicity. Antibiotic Toxicity. Anticancer Drug Toxicity. Environmental and Occupational Nephrotoxicology. Neurotoxicology. Environmental Toxicology. Food Poisoning. Seafood Poisoning. Mushroom Poisonings. Herbal Poisonings. Common Poisonous Household and Garden Plants. Bites and Stings: Terrestrial Envenomings. Common Arthropod Vectors of Infectious Diseases. Tick Paralysis. Bites and Stings: Marine Envenomings. Voodoo, Hoodoo, and Cajun Traditions and Poisonings. Industrial and Occupational Toxicology. Volatile Organic Chemicals. Petrochemical Toxicity. Industrial Gas Exposures and Occupational Lung Diseases. Metal and Metalloid Poisonings. Pesticide Poisonings: Insecticides, Rodenticides, and Herbicides. Radiation Toxicology. Chemical, Biological, and Radiological Weapons and Warfare. Workplace Substance Abuse Monitoring. Miscellaneous Toxicants. Epidemiology and Statistics for Toxicology. Epidemiology and Statistics for Toxicology. Index.
£210.00
Taylor & Francis Inc Chemistry of Heterocyclic Compounds
Book SynopsisThis book discusses the structure, synthesis, and reactivity of heterocyclic compounds. It covers nomenclature, conformational aspects, aromatic stabilization and biological activity of heterocyclic compounds. The book also includes discussions of biochemical processes involving destruction of heterocyclic rings. It includes problem sets that help readers to understand and apply the principles of heterocyclic reactivity and synthesis. The inclusion of more advanced material and references make the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry, particularly in the pharmaceutical and agrochemical industries. Table of ContentsIntroduction. Nomenclature of Heterocyclic Compounds. Three-Membered Heterocyclic Compounds with One Hetero Atom. Three-Membered Heterocyclic Compounds with Two Hetero Atoms. Four-Membered Heterocyclic Compounds with One Hetero Atom. Four-Membered Heterocyclic Compounds with Two Hetero Atoms. Five-Membered Heterocyclic Compounds with One Hetero Atom. Bicyclic Ring Systems Derived from Pyrrole, Furan and Thiophene. Five-Membered Heterocyclic Compounds with Two Hetero Atoms. Bicyclic Ring Systems Derived from pyrazole, imidazole, oxazole,isoxazole and thiazole. Six-Membered Heterocyclic Compounds with One Hetero Atom. Bicyclic Ring Systems Derived from Pyridine. Tricyclic Ring System Derived from Pyridine. Six-Membered Heterocyclic Compounds with Two Hetero Atoms. Bicyclic Ring Systems Derived from Pyridazine, pyrimidine, pyrazine. Seven-Membered Heterocyclic Compounds.
£130.06
Taylor & Francis Ltd Quantitative Pharmacology
Book SynopsisPKPD awareness is vital if we are to attempt to relate preclinical results to the acute and long term consequences in humans. The debate on whether preclinical findings can be translated to the human usage is still engaging scientists across industry, academia and regulatory bodies. Pharmacokinetics (PK) and pharmacodynamics (PD) comprise traditionally distinct disciplines within pharmacology, the study of the interaction of drugs with the body. It is our intention to show that by deliberately, intimately and systematically integrate these disciplines our understanding of drugs and the efficiency and effectiveness of drug discovery and development may be greatly enhanced. The book is therefore written with a broad audience in mind and focuses on concepts. Pharmacologists of all sorts, safety scientists, pharmacokineticists, medicinal chemists, clinicians, statisticians, veterinarians, animal science professionals, project leaders and students of medical, pharmaceutical and veterinarTrade Review"… provides very attractive and comprehensive reading for a broad audience—inside as well as outside Pharma—with interest in integrating PK and PD observations for greater understanding of how to connect drug fate and treatment consequences in vivo."—Professor Arvid Carlsson, Nobel Laureate, Gothenburg University"I consider the book by Gabrielsson and Hjorth to be very useful for in depth studies by scientists working with drug development and experimentalists in clinical pharmacology. It combines the analysis of effects versus time patterns with kinetic corollaries in a most comprehensive way. Moreover, it is a book of great graphical beauty exceptionally styled with a cover painted by one of the authors."--Gunnar Alvan MD PhD, Emeritus professor and former Director General of the Swedish Medical Products Agency"… provides very attractive and comprehensive reading for a broad audience—inside as well as outside Pharma—with interest in integrating PK and PD observations for greater understanding of how to connect drug fate and treatment consequences in vivo."—Professor Arvid Carlsson, Nobel Laureate, Gothenburg University"I consider the book by Gabrielsson and Hjorth to be very useful for in depth studies by scientists working with drug development and experimentalists in clinical pharmacology. It combines the analysis of effects versus time patterns with kinetic corollaries in a most comprehensive way. Moreover, it is a book of great graphical beauty exceptionally styled with a cover painted by one of the authors."--Gunnar Alvan MD PhD, Emeritus professor and former Director General of the Swedish Medical Products AgencyTable of ContentsIntroduction - What is PK/PD and Quantitative Pharmacology. Principles of kinetics from a pharmacodynamic point of view. Principles of plasma protein binding. Principles of dose, time and flow dependencies. Principles of rapid concentration-response equilibria. Time delays between plasma concentration and response. Principles of inter-species scaling.
£152.56
Taylor & Francis Inc Implementing Reproducible Research
Book SynopsisIn computational science, reproducibility requires that researchers make code and data available to others so that the data can be analyzed in a similar manner as in the original publication. Code must be available to be distributed, data must be accessible in a readable format, and a platform must be available for widely distributing the data and code. In addition, both data and code need to be licensed permissively enough so that others can reproduce the work without a substantial legal burden.Implementing Reproducible Research covers many of the elements necessary for conducting and distributing reproducible research. It explains how to accurately reproduce a scientific result. Divided into three parts, the book discusses the tools, practices, and dissemination platforms for ensuring reproducibility in computational science. It describes: Computational tools, such as Sweave, knitr, VisTrails, Sumatra, CDE, and the Declaratron syTrade Review"This collection brings together the expertise and experience of numerous authors and is likely to be valuable to scientists and statisticians alike. … This book should have broad appeal … introduces some extremely useful tools and practices from leaders in the field. On top of that, it also contains an exciting vision for the future of scientific research. … The challenge of reproducibility in the computational era is being confronted across the sciences, with each field developing its own tools and best practices. This book is an important step in bringing together a broad group of scientists to share what has been learned."—Journal of the American Statistical Association, June 2015 "The book as a whole has something for everybody and provides an interesting snapshot of the available tools, platforms, and good practices for researchers as the scientific community aims to be more self-correcting."—Journal of Statistical Software, October 2014 "Three recent books have significantly influenced how I use R in reproducible work: Dynamic Documents with R and knitr by Yihui Xie, Reproducible Research with R and RStudio by Christopher Gandrud, and Implementing Reproducible Research edited by Victoria Stodden, Friedrich Leisch, and Roger D. Peng … I recommend all three books to R users at any level. There really is something here for everyone."—Richard Layton, PhD, PE, Rose-Hulman Institute of Technology, Terre Haute, Indiana, USA "In total, this book provides information on almost all aspects of reproducible research in the open science environment … I would recommend this book to anybody who wants to learn more about reproducible research in the context of open science."—Biometrical Journal Table of ContentsTools: knitr: A Comprehensive Tool for Reproducible Research in R. Reproducibility Using VisTrails. Sumatra: A Toolkit for Reproducible Research. CDE: Automatically Package and Reproduce Computational Experiments. Reproducible Physical Science and the Declaratron. Practices and Guidelines: Developing Open-Source Scientific Practice. Reproducible Bioinformatics Research for Biologists. Reproducible Research for Large-Scale Data Analysis. Practicing Open Science. Reproducibility, Virtual Appliances, and Cloud Computing. The Reproducibility Project: A Model of Large-Scale Collaboration for Empirical Research on Reproducibility—Open Science Collaboration. What Computational Scientists Need to Know about Intellectual Property Law: A Primer. Platforms: Open Science in Machine Learning. RunMyCode.org: A Research-Reproducibility Tool for Computational Sciences. Open Science and the Role of Publishers in Reproducible Research. Index.
£71.99
Taylor & Francis Inc Biogeography and Biodiversity of Western Atlantic
Book SynopsisShallow water marine molluscan faunas are distributed in a pattern of distinct, geographically definable areas. This makes mollusks ideal for studying the distribution of organisms in the marine environment and the processes and patterns that control their evolution. Biogeography and Biodiversity of Western Atlantic Mollusks is the first book to use quantitative methodologies to define marine molluscan biogeographical patterns. It traces the historical development of these patterns for the subtropical and tropical western Atlantic. The book discusses the multistage process of evolving new taxa caused by eustatic fluctuations, ecological stress, and evolutionary selection. Drawing on his decades of intensive field work, the author defines three western Atlantic molluscan provinces and 15 subprovinces based on his Provincial Combined Index, a modern refinement of Valentineâs 50% rule. The faunal provincesâCarolinian, Caribbean, and Brazilianâare discussed in detail. TheTrade Review"Professor Petuch draws upon an extraordinary wealth of personal experience and many decades of field work studying both recent and fossil mollusks throughout the western Atlantic, and has produced a prolific body of publications on these faunas. … [He] is to be commended for clearly and succinctly defining a useful tool for quantifying faunal distinctions among geographic regions. This methodology can also be used to produce a series of testable hypotheses that will serve both as a foundation and as a point of departure for additional research into the effects of geography and ecology on the evolution and diversification of faunas."—From the Foreword by M. G. Harasewych, Ph.D., National Museum of Natural History, Smithsonian InstitutionTable of ContentsIntroduction: American Molluscan Faunas in Time and Space. The Molluscan Provincial Concept in the Tropical Western Atlantic. Provinces of the Tropical Western Atlantic. Molluscan Biodiversity in the Georgian Subprovince. Molluscan Biodiversity in the Subprovinces of the Florida Peninsula. Southern and Western Subprovinces of the Carolinian Province. Northern Subprovinces of the Caribbean Province. Molluscan Biodiversity in the Nicaraguan Subprovince. Molluscan Biodiversity in the Venezuelan Subprovince. Molluscan Biodiversity in the Grenadian and Surinamian Subprovinces. Northern Subprovinces of the Brazilian Province. Molluscan Biodiversity in the Paulinian Subprovince. Bibliography. Appendices. Index.
£171.00
Taylor & Francis Inc Bioengineered Nanomaterials
Book SynopsisMany varieties of new, complex diseases are constantly being discovered, which leaves scientists with little choice but to embrace innovative methods for controlling the invasion of life-threatening problems. The use of nanotechnology has given scientists an opportunity to create nanomaterials that could help medical professionals in diagnosing and treating problems quickly and effectively. Bioengineered Nanomaterials presents in-depth information on bioengineered nanomaterials currently being developed in leading research laboratories around the world. In particular, the book focuses on nanomaterials for biomedical applications.This collection brings together novel methodologies and strategies adopted in the research and development of bioengineered nanomaterials and technology. Renowned international researchers discuss topics including: Nanoemulsions as a vaccine adjuvant Bioceramic nanomaterials in medical applications NaturaTable of ContentsEmerging Potential of Nanoparticles for the Treatment of Solid Tumors and Metastasis. Aptamer–Nanomaterial Conjugates for Medical Applications. Recent Advances in Immobilization Strategies in Biomaterial Nanotechnology for Biosensors. Nanofibers and Nanoparticles in Biomedical Applications. Nanoemulsions as a Vaccine Adjuvant. Inorganic Nanomaterials of Carbonate Apatite as Intracellular Nucleic Acid/Drug Transporters. Bioceramic Nanomaterials in Medical Applications. Imaging and Triggered Release through Design of Ultrastable Core–Shell Iron Oxide Nanoparticles. Natural and Synthetic Nanoporous Membranes for Cell Encapsulation Therapy. Lipid and Cyclodextrin Nanocarriers Loading Bioactive Agents: Stabilization on Polymeric Supports. Silver Nanoparticles: Nanotoxicity Testing and Bioapplications. Nanoparticle Production for Biomedical Applications via Laser Ablation Synthesis in Solution. Nanomedicine in Brain Tumors. Inorganic Nanoparticle Materials for Controlled Drug Delivery Systems. Gold Nanoshells and Carbon Nanotubes as a Therapeutic Tool for Cancer Diagnosis and Treatment. Bioinspired Nanomaterials for Bone Tissue Engineering. Index.
£237.50
Taylor & Francis Inc RNAseq Data Analysis
Book SynopsisThe State of the Art in Transcriptome Analysis RNA sequencing (RNA-seq) data offers unprecedented information about the transcriptome, but harnessing this information with bioinformatics tools is typically a bottleneck. RNA-seq Data Analysis: A Practical Approach enables researchers to examine differential expression at gene, exon, and transcript levels and to discover novel genes, transcripts, and whole transcriptomes.Balanced Coverage of Theory and Practice.Each chapter starts with theoretical background, followed by descriptions of relevant analysis tools and practical examples. Accessible to both bioinformaticians and nonprogramming wet lab scientists, the examples illustrate the use of command-line tools, R, and other open source tools, such as the graphical Chipster software.The Tools and Methods to Get Started in Your Lab. Taking readers through the whole data analysis workflow, this self-contained guide provides a detailed oveTrade Review"Next-generation sequencing (NGS) is without doubt among the last decade’s most important technological advance in molecular biology, and RNA sequencing is its most common application, rapidly becoming an indispensable tool in drug discovery and biomarker identification. Given the complexity and fast-paced evolution of the NGS methodology, it may seem overwhelming to a novice to figure out where to get started. RNA-seq Data Analysis: A Practical Approach solves this problem: the single volume provides the reader with a wealth of details extending from the very fundamentals of NGS technology to comprehensive hands-on instructions on how to interpret your freshly baked sequencing reads. After reading this book, you will have all the necessary information to start putting RNA-seq to work answering your research questions."—Dr. Satu Nahkuri, Pharma Research and Early Development, F. Hoffmann-La Roche Ltd."This is a fantastic book and a real resource for anyone embarking or already working in RNA-seq data analysis. It is a practical guide that provides layers of information to the reader to comprehend the different steps and options when analysing RNA-seq data. The content and style of the book are great and the authors clearly explain and provide well-rounded examples. This book stands out among others since it is very easy to follow and does not require a strong programming or statistical background. It is obvious the authors have experience with explaining and probably teaching others on how to perform RNA-seq analysis. I highly recommend this book to students, researchers, as well as trainers in RNA-seq data analysis."—Dr. Maria Victoria Schneider (Vicky), The Genome Analysis Centre, UK"It is really a very practical book for both wet lab biologists and computer scientists working on RNA-seq projects. The book is clearly written with a general introduction to RNA-seq in Chapter 1 and a brief description to RNA-seq data analysis in Chapter 2. Detailed information of computational methods, analysis pipelines, and software tools are presented in the remaining chapters with some real examples. I believe that this book will serve not only as a textbook for an introductory course of omics data analysis but also as a guideline for researchers working on RNA-seq projects."—Jingchu Luo, Professor, Peking University"RNA-seq is currently the best method for genome-wide transcriptional profiling of cells in about any organism. This book includes all the key steps, in generally the same organization, that we’ve found to be effective when training biologists and bioinformaticians in RNA-seq analysis. It’s a good guide and reference for RNA-seq that can get analysts started (or keep them going) while avoiding much of the time-consuming literature, documentation, and Web searches at each step of the pipeline. It covers a broad (but not overwhelming) selection of popular methods without the typical bias of an author’s research emphasis."—George W. Bell, Ph.D., Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA"In modern life sciences, it is increasingly the bioinformatics aspect that holds the essential key to successful research projects and discoveries, albeit often poorly understood, or even regarded as a ‘black box.’ This is precisely the point at which RNA-seq Data Analysis: A Practical Approach comes in. This book, a brilliant compilation of all different aspects of RNA-sequencing analyses, opens up this ‘black box’ and reveals all of its inner workings. It covers all the basic principles while maintaining a tight focus on the practical aspects of successful analyses, including discussing caveats and possible pitfalls. Following this spirit throughout, it is intuitively structured and easy to read, making it attractive both for researchers who want to quickly deepen their understanding of RNA-seq processing and for use as teaching material in the classroom for the scientists of the future."—Manfred Grabherr, Department of Medical Biochemistry and Microbiology, Uppsala University"I feel that this is a marvelous book and will be of invaluable use to support bioinformaticians, graduate students, and the occasional user of the RNA-seq technology. It has great depth of content and addresses the key areas of designing your study and making sense of the data. It covers the typical scenarios that a services bioinformatician is likely to encounter and I can see this book having a place on desks of scientists across academia and industry."—Stephen Rudd, Head of Computational Biology, University of Queensland"I strongly recommend RNA-seq Data Analysis: A Practical Approach to any scientist who plans to do sequencing experiments, even if he will not analyze the data by himself. The book gives in the first parts very important outlines of the sequencing technology and how it is working. … Going further, the book covers all state-of-the-art techniques of RNA-seq analysis in a very profound yet clear way and will be of great value even for the advanced bioinformatician as a reference work. … a must-have recommendation to everyone working in the molecular biology field … Even as a bioinformatician with over 15 years of experience in this field, I found many valuable details and some yet not known facts about sequencing data analysis."—Oliver Heil, Bioinformatician, German Cancer Research Center (DKFZ)"Many people are interested in applying RNA-seq to examine the transcriptome of their organism of interest but they are finding it difficult to apply it in their own laboratories. … In this book, RNA-seq is introduced by describing the different platforms and then the reader is taken in a systematic way through the process of analyzing RNA-seq data using several free open source tools. This book will be of interest to people starting with RNA-seq."—Dr. Etienne de Villiers, Bioinformatics Group Leader, KEMRI-Wellcome Trust Research Programme (KWTRP), and Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford"Next-generation sequencing (NGS) is without doubt among the last decade’s most important technological advance in molecular biology, and RNA sequencing is its most common application, rapidly becoming an indispensable tool in drug discovery and biomarker identification. Given the complexity and fast-paced evolution of the NGS methodology, it may seem overwhelming to a novice to figure out where to get started. RNA-seq Data Analysis: A Practical Approach solves this problem: the single volume provides the reader with a wealth of details extending from the very fundamentals of NGS technology to comprehensive hands-on instructions on how to interpret your freshly baked sequencing reads. After reading this book, you will have all the necessary information to start putting RNA-seq to work answering your research questions."—Dr. Satu Nahkuri, Pharma Research and Early Development, F. Hoffmann-La Roche Ltd."This is a fantastic book and a real resource for anyone embarking or already working in RNA-seq data analysis. It is a practical guide that provides layers of information to the reader to comprehend the different steps and options when analysing RNA-seq data. The content and style of the book are great and the authors clearly explain and provide well-rounded examples. This book stands out among others since it is very easy to follow and does not require a strong programming or statistical background. It is obvious the authors have experience with explaining and probably teaching others on how to perform RNA-seq analysis. I highly recommend this book to students, researchers, as well as trainers in RNA-seq data analysis."—Dr. Maria Victoria Schneider (Vicky), The Genome Analysis Centre, UK"It is really a very practical book for both wet lab biologists and computer scientists working on RNA-seq projects. The book is clearly written with a general introduction to RNA-seq in Chapter 1 and a brief description to RNA-seq data analysis in Chapter 2. Detailed information of computational methods, analysis pipelines, and software tools are presented in the remaining chapters with some real examples. I believe that this book will serve not only as a textbook for an introductory course of omics data analysis but also as a guideline for researchers working on RNA-seq projects."—Jingchu Luo, Professor, Peking University"RNA-seq is currently the best method for genome-wide transcriptional profiling of cells in about any organism. This book includes all the key steps, in generally the same organization, that we’ve found to be effective when training biologists and bioinformaticians in RNA-seq analysis. It’s a good guide and reference for RNA-seq that can get analysts started (or keep them going) while avoiding much of the time-consuming literature, documentation, and Web searches at each step of the pipeline. It covers a broad (but not overwhelming) selection of popular methods without the typical bias of an author’s research emphasis."—George W. Bell, Ph.D., Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA"In modern life sciences, it is increasingly the bioinformatics aspect that holds the essential key to successful research projects and discoveries, albeit often poorly understood, or even regarded as a ‘black box.’ This is precisely the point at which RNA-seq Data Analysis: A Practical Approach comes in. This book, a brilliant compilation of all different aspects of RNA-sequencing analyses, opens up this ‘black box’ and reveals all of its inner workings. It covers all the basic principles while maintaining a tight focus on the practical aspects of successful analyses, including discussing caveats and possible pitfalls. Following this spirit throughout, it is intuitively structured and easy to read, making it attractive both for researchers who want to quickly deepen their understanding of RNA-seq processing and for use as teaching material in the classroom for the scientists of the future."—Manfred Grabherr, Department of Medical Biochemistry and Microbiology, Uppsala University"I feel that this is a marvelous book and will be of invaluable use to support bioinformaticians, graduate students, and the occasional user of the RNA-seq technology. It has great depth of content and addresses the key areas of designing your study and making sense of the data. It covers the typical scenarios that a services bioinformatician is likely to encounter and I can see this book having a place on desks of scientists across academia and industry."—Stephen Rudd, Head of Computational Biology, University of Queensland"I strongly recommend RNA-seq Data Analysis: A Practical Approach to any scientist who plans to do sequencing experiments, even if he will not analyze the data by himself. The book gives in the first parts very important outlines of the sequencing technology and how it is working. … Going further, the book covers all state-of-the-art techniques of RNA-seq analysis in a very profound yet clear way and will be of great value even for the advanced bioinformatician as a reference work. … a must-have recommendation to everyone working in the molecular biology field … Even as a bioinformatician with over 15 years of experience in this field, I found many valuable details and some yet not known facts about sequencing data analysis."—Oliver Heil, Bioinformatician, German Cancer Research Center (DKFZ)"Many people are interested in applying RNA-seq to examine the transcriptome of their organism of interest but they are finding it difficult to apply it in their own laboratories. … In this book, RNA-seq is introduced by describing the different platforms and then the reader is taken in a systematic way through the process of analyzing RNA-seq data using several free open source tools. This book will be of interest to people starting with RNA-seq."—Dr. Etienne de Villiers, Bioinformatics Group Leader, KEMRI-Wellcome Trust Research Programme (KWTRP), and Centre for Tropical Medicine, Nuffield Department of Medicine, University of OxfordTable of ContentsIntroduction. Quality Control. Mapping, and Assembly. Differential Expression. Analysis of Small Non-Coding RNAs.
£77.12
Taylor & Francis Inc The Integrated Nervous System
Book SynopsisThis innovative textbook is modelled on problem-based learning. It bridges the gap between academic neuroanatomy and clinical neurology and effectively takes the reader from the classroom to the clinic, so that learning can be applied in practice.This second edition has been updated and expanded to include many more clinical cases within both the book and the accompanying Wweb site. This book and the associated Web site will be of practical value to all the professionals who deal with people who have neurological conditions, as well as being invaluable to medical students and residents. This includes physiatrists (rehabilitation medicine specialists), physiotherapists, occupational therapists and speech therapists, and nurses who specialize in the care of neurological patients. We think that this text will also be of value for family physicians and specialists in internal medicine and pediatrics, all of whom must differentiate between organic pathology of the neTable of ContentsSynopsis of the Nervous System. The Neurological Examination. Clinical Problem Solving. Fifi. Cletus. Ernesto. Bernie. Etienne. Cheryl. Patty. Didi. Armand. Mickey. Neurorehabilitation. Ethics and Neurology.
£89.99
Hodder Education Edexcel A Level Biology Student Book 1
Book SynopsisExam Board: EdexcelLevel: AS/A-levelSubject: BiologyFirst Teaching: September 2015First Exam: June 2016Endorsed by Edexcel Supports Pearson Edexcel Level 3 Advanced GCE in Biology B (9BI0) specificationBuild investigative skills, test understanding and apply biological theory to topical examples with this Edexcel Year 1 Student Book- Supports all 16 required practicals with activities and questions to help students explain procedures, analyse data and evaluate results- Provides clear definitions, as well as explanations, of the meanings of all technical vocabulary needed for the new specification- Helps bring students up to speed with a summary of prior knowledge and diagnostic questions at the start of each chapter- Offers assessment guidance with Exam Practice Questions at the end of each chapter, graded by difficulty to support progression, along with Challenge Questions to stretc
£41.88
Hodder Education Edexcel A Level Biology Student Book 2
Book SynopsisExam Board: EdexcelLevel: AS/A-levelSubject: BiologyFirst Teaching: September 2015First Exam: June 2016Endorsed for Edexcel Supports Pearson Edexcel Level 3 Advanced GCE in Biology B (9BI0) specification.Build investigative skills, test understanding and apply biological theory to topical examples with this Edexcel Year 2 Student Book. - Supports all 16 required practicals with activities and questions to help students explain procedures, analyse data and evaluate results- Provides clear definitions, as well as explanations, of the meanings of all technical vocabulary needed for the new specification- Helps bring students up to speed with a summary of prior knowledge and diagnostic questions at the start of each chapter- Offers assessment guidance with Exam Practice Questions at the end of each chapter, graded by difficulty to support progression, along with Challenge Questions to stretc
£41.88
Hodder Education OCR A Level Biology Student Book 1
Book SynopsisExam Board: OCRLevel: A-levelSubject: BiologyFirst Teaching: September 2015First Exam: June 2016This is an OCR endorsed resourceEncourage students to learn independently and build on their knowledge with this textbook that leads students seamlessly from basic biological concepts to more complicated theories.- Develop experimental, analytical and evaluation skills with activities that introduce the practicals required by OCR and other experimental investigations in Biology- Provide assessment guidance with synoptic questions and multiple choice questions throughout the book, and revision tips and skills all in one chapter- Strengthen understanding of key concepts with contemporary and engaging examples, illustrated with accessible diagrams and images - Give students the opportunity to apply their knowledge and understanding of all aspects of practical work with Test Yourself Questions and ExaTrade ReviewThe Dedicated mathematics skills chapter is a wonderful inclusion. All the maths skills a student will need to demonstrate can be found, explained and exemplified in one place. -- A Popperwell, Science Teacher * Abigail Lambert *The book explains transcription and translation really well and better than our other sourceIt is clearly laid outThere are thorough explanations stating the key points which are easy to pick outQuestions are directly related to specification content whereas in our other AS text the questions are vague and not linked directly with contentDiagrams are clear and well labelled and aesthetically pleasing, they are easy to understand and accurateThe key terms and tip boxes contain relevant information to extend our knowledge in a way that is useful to us when we are revising -- A level Students, Gillingham School in Dorset. * Abigail Lambert *
£41.88
Hodder Education My Revision Notes OCR A Level Biology A
Book SynopsisExam Board: OCRLevel: A-LevelSubject: BiologyFirst Teaching: September 2015First Exam: Summer 2016With My Revision Notes: OCR A Level Biology A you can:- Manage your own revision with step-by-step support from experienced teacher and examiner Frank Sochacki- Apply biological terms accurately with the help of definitions and key words- Plan and pace your revision with the revision planner- Test understanding with questions throughout the book- Get exam ready with last minute quick quizzes available on the Hodder Education website
£23.78
Hodder Education OCR ASA Level Year 1 Biology A Workbook Exchange
Book SynopsisExam Board: OCR Level: A-Level Subject: Biology First Teaching: September 2015 First Exam: Summer 2016Our Student Workbooks build students'' understanding, developing the confidence and exam skills they need, whilst providing ready prepared lesson solutions.- Reinforce and apply topic understanding as classwork or extension tasks, or with revision- Prepare students to meet the demands of the new specification by practising exam technique- Create opportunities for independent learning and self-assessment with answers online- Supplement key resources such as textbooks - Time-saving and economical lesson solutions for both specialist and non-specialist teachers
£10.89
Hodder Education CCEA AS Unit 1 Biology Student Guide Molecules
Book SynopsisReinforce students'' understanding throughout their course; clear topic summaries with sample questions and answers will improve exam technique to achieve higher grades.Written by examiners and teachers, Student Guides: Help students identify what they need to know with a concise summary of the topics examined in the AS and A-level specification Consolidate understanding with exam tips and knowledge check questions Provide opportunities to improve exam technique with sample graded answers to exam-style questions Develop independent learning and research skills Provide the content for generating individual revision notes
£14.71
Hodder Education CCEA A2 Unit 1 Biology Student Guide Physiology
Book SynopsisExam Board: CCEALevel: A-levelSubject: BiologyFirst Teaching: September 2016First Exam: June 2018Reinforce students'' understanding throughout their course; clear topic summaries with sample questions and answers will improve exam technique to achieve higher gradesWritten by examiners and teachers, Student Guides: Help students identify what they need to know with a concise summary of the topics examined in the AS and A-level specification Consolidate understanding with exam tips and knowledge check questions Provide opportunities to improve exam technique with sample graded answers to exam-style questions Develop independent learning and research skills Provide the content for generating individual revision notes
£14.97
Hodder Education CCEA A2 Unit 2 Biology Student Guide Biochemistry
Book SynopsisExam Board: CCEALevel: A-levelSubject: BiologyFirst Teaching: September 2016First Exam: June 2018Reinforce students'' understanding throughout their course; clear topic summaries with sample questions and answers will improve exam technique to achieve higher gradesWritten by examiners and teachers, Student Guides: Help students identify what they need to know with a concise summary of the topics examined in the AS and A-level specification Consolidate understanding with exam tips and knowledge check questions Provide opportunities to improve exam technique with sample graded answers to exam-style questions Develop independent learning and research skills Provide the content for generating individual revision notes
£14.71
Hodder Education CCEA AS Unit 2 Biology Student Guide Organisms
Book SynopsisExam Board: CCEALevel: A-levelSubject: BiologyFirst Teaching: September 2016First Exam: June 2018Reinforce students'' understanding throughout their course; clear topic summaries with sample questions and answers will improve exam technique to achieve higher grades.Written by examiners and teachers, Student Guides: Help students identify what they need to know with a concise summary of the topics examined in the AS and A-level specification Consolidate understanding with exam tips and knowledge check questions Provide opportunities to improve exam technique with sample graded answers to exam-style questions Develop independent learning and research skills Provide the content for generating individual revision notes
£14.97
Hodder Education Biology for the IB Diploma Study and Revision
Book SynopsisExam Board: IBLevel: IBSubject: BiologyFirst Teaching: September 2014First Exam: Summer 16Stretch your students to achieve their best grade with these year round course companions; providing clear and concise explanations of all syllabus requirements and topics, and practice questions to support and strengthen learning. - Consolidate revision and support learning with a range of exam practice questions and concise and accessible revision notes- Practise exam technique with tips and trusted guidance from examiners on how to tackle questions- Focus revision with key terms and definitions listed for each topic/sub topic
£28.49
Edinburgh University Press Deleuze and Evolutionary Theory
Book Synopsis9 essays focus on the significance of Deleuze and Guattari's engagements with evolutionary theory across the full range of their work, from the interpretation of Darwin in 'Difference and Repetition', to the symbiotic alliances of wasp and orchid in 'A Thousand Plateaus'.
£94.50
Edinburgh University Press BergsonS Philosophy of Biology
Book SynopsisIn this book, Tano S. Posteraro focuses on Bergson's theory of evolution. He presents an alternative Bergson: not a phenomenologist whose central datum is the conscious experience of lived time or the lived body in time, but a systematic philosopher of biology with a robust, prescient and largely workable evolutionary programme.
£18.99
Taylor & Francis Inc Nanotoxicology
Book SynopsisSince the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines.Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer proTable of ContentsImpacts of Nanotechnology on Biomedicine. Introduction to Biomedical Nanotechnology. Impact of Bionanointeractions of Engineered Nanoparticles for Nanomedicine. Rational Approach for the Safe Design of Nanomaterials. Characterization of Manufactured Nanomaterials, Dispersion, and Exposure for Toxicological Testing. Exposure. Workplace Inhalation Exposure to Engineered Nanomaterials: Detection, Measurement, and Assessment. Nanotechnology in Consumer Products: Addressing Potential Health and Safety Implications for Consumers. Modeling. Quantitative Nanostructure–Activity Relationships: From Unstructured Data to Predictive Models for Designing Nanomaterials with Controlled Properties. Pharmacokinetics and Biodistribution of Nanomaterials. Methodologies and Techniques. Advanced Methodologies and Techniques for Assessing Nanomaterial Toxicity: From Manufacturing to Nanomedicine Screening. Detection Methods for the In Vivo Biodistribution of Iron Oxide and Silica Nanoparticles: Effects of Size, Surface Chemistry, and Shape. Quantitative Single-Cell Approaches to Assessing Nanotoxicity in Nanomedicine Systems. Imaging Techniques for Nanoparticles in Skin. Hazards. Safety Implications of Nanomaterial Exposure to Skin. Interspecies Comparisons of Pulmonary Responses to Fine and/or Nanoscale Particulates: Relevance for Humans of Particle-Overload Responses in the Rat Model. Current In Vitro Models for Nanomaterial Testing in Pulmonary Systems. Nanoparticles and the Immune System. Carbon Nanotubes and Cardiovascular Disease. Single- and Multiwalled Carbon Nanotubes Toxicity and Potential Applications in Neuroregeneration. Current In Vitro Models for Nanomaterial Testing: The Reproductive System. Current In Vitro Models for Nanomaterial Testing: Genotoxicity Issues. Cell-Based Targeting of Anticancer Nanomaterials to Tumors. Silver Nanoparticles in Biomedical Applications. Cytotoxicity of Conjugated and Unconjugated Semiconductor and Metal Nanoparticles. Risk Assessment. Issues Related to Risk Assessment of Nanomaterials.Risk Assessment of Engineered Nanomaterials: State of the Art and Roadmap for Future Research. Index.
£171.00
Taylor & Francis Inc A Handbook of Statistical Analyses using R
Book SynopsisLike the best-selling first two editions, A Handbook of Statistical Analyses using R, Third Edition provides an up-to-date guide to data analysis using the R system for statistical computing. The book explains how to conduct a range of statistical analyses, from simple inference to recursive partitioning to cluster analysis.New to the Third Edition Three new chapters on quantile regression, missing values, and Bayesian inference Extra material in the logistic regression chapter that describes a regression model for ordered categorical response variables Additional exercises More detailed explanations of R code New section in each chapter summarizing the results of the analyses Updated version of the HSAUR package (HSAUR3), which includes some slides that can be used in introductory statistics courses Whether you're a data analyst, scientist, or student, this handTrade Review“I truly appreciate how grounded in practicality this book is—and the way its chapters are structured really underlines this. Furthermore, all the datasets are interesting and vary widely in subject matter. If nothing else, this book is an excellent source of examples one might use to illustrate a variety of statistical techniques. … it offers a lot of good places to start if one wants to analyze data. … The book comes hand-in-hand with an R package, HSAUR3, with all the data and the code used in the text. The book is thus fully reproducible. Overall, it provides a great way for a statistician to get started doing a wide variety of things in the R environment. It would be particularly useful, then, for working statisticians looking to change their software. The book cites all the relevant packages one might need, which is quite nice for those attempting to navigate the vast array of packages freely available, and is quite clear in its presentation of the code. Between this and the datasets, it makes for quite a valuable and enjoyable reference.”—The American Statistician, August 2015"… a handy primer for using R to perform standard statistical data analysis. … students, analysts, professors, and scientists: if you are looking to add R to your toolkit for analyzing data statistically, then this book will get you there."—Kendall Giles on his blog, September 2014Praise for the Second Edition:"I find the book by Everitt and Hothorn quite pleasant and bound to fit its purpose. The layout and presentation [are] nice. It should appeal to all readers as it contains a wealth of information about the use of R for statistical analysis. Included seasoned R users: When reading the first chapters, I found myself scribbling small lightbulbs in the margin to point out features of R I was not aware of. In addition, the book is quite handy for a crash introduction to statistics for (well-enough motivated) nonstatisticians."—International Statistical Review (2011), 79"… an extensive selection of real data analyzed with [R] … Viewed as a collection of worked examples, this book has much to recommend it. Each chapter addresses a specific technique. … the examples provide a wide variety of partial analyses and the datasets cover a diversity of fields of study. … This handbook is unusually free of the sort of errors spell checkers do not find."—MAA Reviews, April 2011Table of ContentsAn Introduction to R. Data Analysis Using Graphical Displays. Simple Inference. Conditional Inference. Analysis of Variance. Simple and Multiple Linear Regression. Logistic Regression and Generalized Linear Models. Density Estimation. Recursive Partitioning. Scatterplot Smoothers and Additive Models. Survival Analysis. Quantile Regression. Analyzing Longitudinal Data I. Analyzing Longitudinal Data II. Simultaneous Inference and Multiple Comparisons. Missing Values. Meta-Analysis. Bayesian Inference. Principal Component Analysis. Multidimensional Scaling. Cluster Analysis. Bibliography. Index.
£64.99
Taylor & Francis Inc Liver Metabolism and Fatty Liver Disease
Book SynopsisNonalcoholic fatty liver disease is one of the most common liver diseases worldwide affecting patients from all ages, races, and ethnic backgrounds. It comprises a spectrum of hepatic pathology ranging from simple steatosis, in which there is an increase of fat accumulation in hepatocytes, to nonalcoholic steatohepatitis and cirrhosis. The significant prevalence of this diseasebetween 15 and 45 percent of the general populationmeans that it contributes to an increased burden of ill health both today and in the future.Liver Metabolism and Fatty Liver Disease addresses the current understanding of the development of nonalcoholic fatty liver disease as well as the clinical aspects of the disease by examining the current knowledge surrounding metabolism in the liver. The book discusses various topics including the involvement of oxidative stress, metabolic effects, and inflammation as well as the effect of nutrition on the development and progression of the disease.Table of ContentsIntroduction to Fatty Liver Disease and Consequences. Fatty Liver Disease and Consequences. Nutrition Role in Liver Protection and Damage.
£155.00
Taylor & Francis Inc Integrated Molecular Evolution
Book SynopsisEvolutionary biology has increasingly relied upon tools developed in molecular biology that allow for the structure and function of macromolecules to be used as data for exploring the patterns and processes of evolutionary change. Integrated Molecular Evolution, Second Edition is a textbook intended to expansively and comprehensive review evolutionary studies now routinely using molecular data. This new edition has been thoroughly updated and expanded, and provides a basic summary of evolutionary biology as well as a review of current phylogenetics and phylogenomics.Reflecting a burgeoning pedagogical landscape, this new edition includes nearly double the number of chapters, including a new section on molecular and bioinformatic methods. Dedicated chapters were added on: Evolution of the genetic code Mendelian genetics and population genetics Natural selection Horizontal gene transfers Animal development and plant development Trade ReviewRogers (molecular biology and evolution, Bowling Green State Univ.) has created an engaging, readable, accessible introduction to the field of molecular evolution. The book is organized in sections that follow a logical progression. A brief discussion of life and the basic features of evolutionary theory is followed by sections on basic macromolecules and cellular processes, Mendelian and population genetics, gene families, means of gene transfer, the developmental processes in multicellular organisms, and methods of molecular analysis and omics. The work ends with chapters devoted to the genomes of various organisms and agents, from viruses through humans. In each chapter, the discussion is tied to how the topic affects or is affected by the process of evolution. Each chapter ends with a summary of key points and contains a list of additional sources. The illustrations are effective and enhance the text. The book will be most useful to readers with a basic knowledge of molecular biology and development, as the background topics are covered in an appropriately succinct fashion. --M. S. Kainz, Ripon College Summing Up: Highly recommended. Upper-division undergraduates through faculty. CHOICE Table of ContentsLIFE AND EVOLUTION. Definitions of Life. Earth and Evolution. BIOMOLECULES. DNA, RNA, and Proteins. The Central Dogma and Beyond. Ribosomes and Ribosomal RNA. Structure of the Genetic Code. DNA Replication. DNA Segregation. GENETICS. Mendelian and Non-Mendelian Characters. Population Genetics. Alleles through Time. Changes to DNA. Infectious Changes to DNA: Viruses, Plasmids, Transposons, and Introns. MULTICELLULARITY. Multigene Families. Horizontal Gene Transfer. Development: Part I—Cooperation Among Cells. Development: Part II—Plants. Cancer. MOLECULAR BIOLOGY AND BIOINFORMATIC METHODS. Extraction and Quantification of Biological Molecules. Recombinant DNA and Characterization of Biological Molecules. Sequencing and Alignment Methods. OMICS: Part I. OMICS: Part II. Species Concepts and Phylogenetics. Phylogenetic Networks and Reticulate Evolution. Phylogenomics and Comparative Genomics. GENOMES. RNA Viruses. DNA Viruses. Bacteria and Archaea. Mutualists and Pathogens. Endosymbionts and Organelles. Protein Trafficking. Eukaryotic Genomes. Human Genome.
£120.00
Taylor & Francis Inc Biosimilar Clinical Development Scientific
Book SynopsisBiosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in clinical development, this book discusses various potential drug development strategies, the design and analysis of pharmacokinetics (PK) studies, and the design and analysis of efficacy studies.Trade Review"Thus, the book Biosimilar Clinical Development contains five chapters discussing general issues involving biosimilars. The remaining six chapters present statistical methods, many of which are new, and their applications in bioequivalence and biosimilarity studies; they are really research papers. . . It will appeal to readers interested in biosimilars and especially in their statistical assessments."~Laszlo Endrenyi, University of Toronto “The book is edited by a team of renowned experts from both statistics and biosimilar clinical development. It contains 11 chapters, covering not only statistical issues but also pre-clinical and clinical development issues not regularly discussed on this kind of book, as well as references to regulatory considerations of upmost importance for statisticians working in the strongly regulated environment of clinical development . . . I strongly recommend the reading of this book. In my opinion, the book should be a must-have reading for professionals who work regularly with biosimilars and want to have an overview of state-of-the art methods for 'hot-topics' in the analysis and planning of clinical trials for this purpose.”~David ManteigasTable of ContentsBiosimilars for Drug Development. Regulatory Requirements on Biosimilars. System Biology in the Context of Biosimilars. Clinical Considerations on Biosimilars. Large Molecules Complete Molecular Confidence (CMC) Development Strategy. Immunogenicity. Interchangeability. Bridging a New Biologic to Its Reference Biologic. How to Account Covariate Effect to Show Non-Inferiority in Biosimilars. Novel Method in Inference of Equivalence in Biosimilars. Multiplicity Adjustment in Equivalence Using Two One-Sided Tests. Bayesian Methods in Biosimilar Studies.
£120.00
Taylor & Francis Inc Practical Homicide Investigation
Book SynopsisRenowned for being THE definitive resource for homicide investigators, Practical Homicide Investigation: Tactics, Procedures, and Forensic Techniques details the recognized protocols used by investigative divisions of major police departments throughout the world. The text is used in most police academies, including the FBI Academy in Quantico, Virginia.Now in its fifth edition, the book begins with a comprehensive discussion of homicide crime scenes and moves chronologically from initial police notification, the correct police response that follows, and the subsequent steps necessary to conduct an intelligent investigation. It then delves into the more technical aspects of homicide investigation, augmented with numerous pictures and full-color illustrations that involve pertinent case histories.This latest edition includes three new chapters along with fully revised chapters with new case histories and techniques that reflect the latest forensicTrade Review"Geberth has succeeded in the impossible. … Practical Homicide Investigation, Fifth Edition, explains every aspect of a homicide investigation, with an easily understood, how-to approach from a professional who has been there. In my opinion, it is essential that the professional involved with the investigation and prosecution of a homicide have a copy…. This is the most outstanding and comprehensive encyclopedia on the tactics, procedures, and forensic techniques of homicide investigations."—Philip G. Schnelwar, Attorney at Law, White Plains, New York"This book leaves no question that now more than ever, a homicide investigation must be based on a mix of the practical and the scientific. In fact, the new chapters and revised materials, along with the descriptive photos in this text … will place this edition in the category of a police text classic, an authoritative standard on the subject, and make this book the most complete homicide textbook available on the market today."—Pierce R. Brooks (Deceased), from the Book's Foreword, Writing about the Previous Edition"One of the most difficult aspects of homicide investigation…is to keep current and up-to-date with techniques, laws and procedures. Vernon Geberth continues to update and review critical matters…relating to the ever-changing world of homicide investigation. If you do not keep up to date with the latest techniques and investigative practices as Vernon explains them, you will wish you had when you are confronted with them on the witness stand at trial. I have prosecuted murder cases for over thirty years in New Mexico, Texas, and Colorado. This book and its accompanying Field Guide are used by me and our local investigators constantly."—James Yontz, Deputy District Attorney, Pueblo, Colorado, USA"Vernon Geberth, a retired NYC homicide detective, is a prominent forensic consultant and the recognized clearinghouse for all things related to death investigations. The 1st edition had become a veritable bible for investigators, so I could just imagine what a 5th edition offered. I couldn’t wait to see it. At a crime scene, investigators should observe, describe, record anything they find, and use proper procedures to collect the evidence. This book goes over every known scenario: inside, outside, typical, atypical, straightforward, ambiguous, staged…you name it. In short, this book is impressive. Geberth leaves no stone unturned. I pride myself on my collection of unusual suicide cases, but he includes some in this book that riveted me."—Psychology Today’s "Shadow Boxing" blog June 2015, Katherine Ramsland. Katherine Ramsland, PhD, an expert on murder and serial crime, teaches forensic psychology and has published 46 books."This newly published 5th edition of Practical Homicide Investigation is 1226 pages in length, and … is a collaboration of information made possible by the author, who has dedicated his life to providing the most up to date reference tool to homicide and death investigators and prosecutors throughout the country. This behemoth of a text continues that legacy …which make this latest edition a valuable tool for any investigator charged with the ‘profound duty and awesome responsibility,’ of conducting a homicide or death investigation."—Detective Mark J. Czworniak (retired), Chicago Police Department, Area North - Homicide Sex Crimes Unit"This edition not only provides the scientific basis for homicide investigation, it also describes in intimate detail the procedures and techniques necessary for a comprehensive and successful investigation. The text is replete with photographs, drawings and illustrations ... including multiple case examples that are very clearly written and pertinent to the science as well as the practical procedures of homicide investigation. This is the most complete text available on the subject ... I highly recommend it to any officer involved in homicide investigation as well as forensic scientists."—Ronald Turco, Past President, American Academy of Psychoanalysis and The American Society of Psychoanalytic Physicians, Former Reserve Police Officer of 30 years"This is a must-have reference for all homicide detectives. This comprehensive opus is nothing less than a masterpiece. The amount of information packed into 1200 pages is astonishing …truly a wonderful resource for all persons investigating and seeking to gain an understanding of every aspect of homicide. No question this text is the gold standard in the field. Truly a remarkable resource."—Donna Pedergast, First Assistant District Attorney, Michigan Attorney General’s Office"Geberth, the world-wide expert on homicide investigation, is the real thing. His chapter on DNA is one of the most readable and comprehensive treatments on the subject. His expertise and clarity make this a must read. All of the twenty-four chapters have been excellently written and revised to make this textbook the continued recognized ‘Bible of Homicide Investigation’ for all members of the criminal justice and legal system."—Edwin T. Dreher, Deputy Chief (Retired), Office of the Chief of Detectives, New York City Police Department"The best book on death investigations just got better. I love the new book … it has been significantly expanded and goes into even greater detail than Geberth’s previous editions. The use of case studies to explain the importance of the different steps is magnificent. The information has been updated to acknowledge the increased role technology plays in death investigations. This is the ultimate manual for death investigations; every homicide investigator should own a copy and use it like a physician’s desk reference."—Larry Hallmark, Detective Lieutenant, Grapevine Texas Police Department"Practical Homicide Investigation, Fifth Edition, will be your one-stop shopping resource for successful death investigations. The updates and additions are massive … the incorporation of today’s forensic and technological advances will keep you on the cutting edge of death investigations."—Larry Thomas, Assistant Director, Kansas Bureau of Investigation (Ret.), BTK Serial Killer Task Force Supervisor"Once again, Vernon Geberth has set a new standard for learned treatises in homicide investigation … (the) Fifth Edition is thoughtful, provocative and, most of all, provides an expert guide for the men and women of our police forces."—Charles S. DeAngelo, Esq., Attorney-at-Law"Practical Homicide Investigation, Fifth Edition …contains just about everything there is to know about death investigations and is a must read for anyone that investigates deaths and homicides." —Heath Taylor, Sheriff, Russell County, Alabama"[With] the first edition to this textbook … and each successive edition, Practical Homicide Investigation has exemplified the most comprehensive and up-to-date compilation of homicide and death investigative knowledge available. This fifth edition is similarly an unsurpassed reference."—Joseph A. Bobak IV, Ph.D., Professor of Criminology and Forensic Investigation, Mount Aloysius College"This intelligent, all-encompassing book is a veritable encyclopedia for successful homicide investigations."—Marvin Skeen, Chief Criminal Investigator, Office of Attorney General of Washington"Vernon Geberth’s Practical Homicide Investigation, Fifth Edition leverages his 46 years of experience with that of many colleagues to put everything you need to know about murder investigation in one place—at your fingertips."—Pete Gagliardi, Author, The 13 Critical Tasks: An Inside-out Approach to Solving More Gun Crime, www.triplebarrelstrategies .com"This comprehensive book is a must-have item for every detective and investigator to use as a guide and reference. Vernon’s Fifth Edition successfully ties together the old-fashioned principles of good investigative police work with the latest advances of forensic science and technology."—Tom Jordan, Judge, District Court, Center Hall, Pennsylvania"Practical Homicide Investigation is to the police profession what the Physicians’ Desk Reference is to the medical profession. In the Preface Geberth writes, ‘A homicide investigator is street smart and book wise.’ This Fifth edition is a one of a kind source that provides professionals the ‘street smart’ with ‘book wise’ in a very practical way."—Anthony D. Magnetto, Police Commissioner (ret), City of Troy, NY Police Dept.Table of ContentsThe Homicide Crime Scene. First Officer’s Duties: General. First Officer’s Duties: Specific. The Preliminary Investigation: The Detectives. Specific Investigative Duties at The Scene. The Crime Scene Photographs. The Crime Scene Sketch. The Homicide Crime Scene Search. Estimating Time of Death. The Identity of the Deceased. Death Notifications. Modes of Death. Suicide. The Investigation of Sex-Related Homicide. Homosexual Homicides. Forensic Application of DNA Analysis. Collection of Evidence.The Autopsy. The News Media in Homicide Investigations. Identification of Suspects. Investigative Assessment: Criminal Personality Profiling. Equivocal Death Investigation. Narcotics Related Homicides. PHI Supervision and Management.
£132.07
Taylor & Francis Inc Phylogenomic Data Acquisition
Book SynopsisPhylogenomics is a rapidly growing field of study concerned with using genome-wide datausually in the form of DNA sequence locito infer the evolution of genes, genomes, and the Tree of Life. Accordingly, this discipline connects many areas in biology including molecular and genomic evolution, systems biology, molecular systematics, phylogeography, conservation genetics, DNA barcoding, and others. With the advent of Next Generation Sequencing in addition to advances in computer hardware and software over the past decade, researchers can now generate unparalleled phylogenomic datasets that are helping to illuminate many areas in the life sciences. This book is an introduction to the principles and practices of gathering these data. Phylogenomic Data Acquisition: Principles and Practice is intended for a broad cross-section of biologists and anyone else interested in learning how to obtain phylogenomic data using the latest methods.Trade Review"There is definitely a need for this book written in the language of the phylogeneticist. The general organization of the book is good. This book addresses a broad range of topics in a way that makes them comprehensible to people who are not experts in bioinformatics and will be extremely influential. Jennings has been in on the ground floor of the multilocus coalescent revolution in phylogenetics."Jim McGuire, University of California Berkeley"Genome sequencing technologies and data collection techniques are changing rapidly, and this book is a great resource for getting up to speed in this exciting field. Jennings outlines the essential data collection strategies that all students entering the field of molecular systematics need to know. "Adam Leaché, University of Washington, Seattle"This new book by evolutionary biologist Bryan Jennings brings together a wealth of useful information allowing researchers to move from start to finish in the rapidly changing field of phylogenomics. It details step-by-step protocols and provides masterful summaries of best practices for the modern phylogeneticist. Graduate students, postdoctoral fellows and principal investigators will find this book extremely useful. Jennings cuts through the jungle of sometimes conflicting information and provides cogent reviews of important topics and guidelines for avoiding common pitfalls."Scott Edwards, Harvard UniversityTable of ContentsIntroduction. PHYLOGENOMIC DATA CHARACTERISTICS AND ACQUISITION. Genomes, Molecular Evolution, and Molecular Markers. DNA Extraction. PCR Theory and Methodology. Loci Acquisition. Sanger and Next Generation DNA Sequencing. UNDERSTANDING AND MAKING GENE TREES: THE UNITS OF PHYLOGENOMIC ANALYSIS. Gene Tree Inference. Advanced Gene Tree Inference. PHYLOGENOMIC ANALYSIS: USING GENE TREES TO ANSWER EVOLUTIONARY QUESTIONS. Gene and Genome Evolution. Primer of Coalescent Theory. Species Tree Inference. Phylogeography I. Phylogeography II. DNA Barcoding and Forensics. Future Prospects. References. Glossary. Answers to End-of-chapter Questions.
£175.00
Taylor & Francis Inc Fennemas Food Chemistry
Book SynopsisThis latest edition of the most internationally respected reference in food chemistry for more than 30 years, Fennema's Food Chemistry, 5th Edition once again meets and surpasses the standards of quality and comprehensive information set by its predecessors. All chapters reflect recent scientific advances and, where appropriate, have expanded and evolved their focus to provide readers with the current state-of-the-science of chemistry for the food industry. This edition introduces new editors and contributors who are recognized experts in their fields.The fifth edition presents a completely rewritten chapter on Water and Ice, written in an easy-to-understand manner suitable for professionals as well as undergraduates. In addition, ten former chapters have been completely revised and updated, two of which receive extensive attention in the new edition including Carbohydrates (Chapter 3), which has been expanded to include a section on MaTrade ReviewSource: Grasas y Aceites Vol 68, No 4 (2017)Name: F. J. HidalgoIn summary, an updated version of this classic textbook in Food Chemistry that has been employed by numerous students and researchers. This new edition maintains the same spirit that previous editions and will continue being as useful as before for both Food Chemistry courses and those wanting to have a deep introduction to some unknown aspects in Food Chemistry.Table of ContentsIntroduction. Major Food Components. Water and Ice. Carbohydrates. Lipids. Amino Acids, Peptides, and Proteins. Enzymes. Dispersed Systems: Basic considerations. Minor Food Components. Vitamins. Minerals. Colorants. Flavors. Food Additives. Bioactive Substances. Nutraceuticals and Toxicants. Food Systems. Characteristics of Milk. Post-Mortem Physiology of Edible Muscle Tissues. Post-harvest Physiology of Edible Plant Tissues.
£215.00
Taylor & Francis Inc Health Technology Assessment
Book SynopsisThe term health technology refers to drugs, devices, and programs that can improve and extend quality of life. As decision-makers struggle to find ways to reduce costs while improving health care delivery, health technology assessments (HTA) provide the evidence required to make better-informed decisions.This is the first book that focuses on the statistical options of HTAs, to fully capture the value of health improvements along with their associated economic consequences. After reading the book, readers will better understand why some health technologies receive regulatory or reimbursement approval while others do not, what can be done to improve the chances of approval, as well as common shortcomings of submissions for drug and device reimbursement.The book begins by contrasting the differences between regulatory approval and reimbursement approval. Next, it reviews the principles and steps for conducting an HTA, including the reasons why different agencies will hTable of ContentsRegulation, Reimbursement and Health Technology Assessment. Requirements and Sources of Data to Complete an HTA. Meta-Analysis. Network Meta-Analysis. Bayesian Methods. Survival Analysis. Costs and Cost of Illness Studies. Health-Related Quality of Life. Missing Data Methods.
£105.00
