Public health and preventive medicine Books

3453 products


  • Is Cancer Inevitable

    Johns Hopkins University Press Is Cancer Inevitable

    Book SynopsisHow can new understandings about cancer cell interactions help doctors better control, and eventually cure, cancer?Cancer is a formidable enemy. In fact, people born in America since 1960 face a one in two chance of being diagnosed with cancer in their lifetimes. However, there's growing evidence that fewer cancers will be death sentences for patients. New approaches and understandings are transforming the medical world, increasing success rates for remissions, disease management, and cures. Dr. Ashani Weeraratna is at the forefront of this new level of care. In Is Cancer Inevitable?, Weeraratnaa pioneering melanoma researcher whose work explores the role aging plays in cancer cells' spread and drug resistancegives readers an inside look at several of the latest cancer advances. Detailing the actions that are reducing the disease's impact and exploring what the future may hold, she explains how the molecular mechanisms involved in metastasis and the cells' microenvironments influence cTable of ContentsPreface 1. The Nature of Cancer2. The Role of Cancer Research3. Breaking Through4. Is Cancer Inevitable?AcknowledgmentsNotesIndex

    £13.30

  • Ethically Challenged

    Johns Hopkins University Press Ethically Challenged

    7 in stock

    Book SynopsisRevealing the dark truth about the impact of predatory private equity firms on American health care. Won Gold from the Axiom Book Award in the Category of Business Ethics, the Benjamin Franklin Awards by the Independent Book Publishers Association and the North American Book Award in the Catergory of Business Finance, Finalist of the American Book Fest Best Book Social Change and Current Events by the American Book FestPrivate equity (PE) firms pervade all aspects of our modern lives. Unlike other corporations, which generally manufacture products or provide services, they leverage considerable debt and other people's money to buy and sell businesses with the sole aim of earning supersized profits in the shortest time possible. With a voracious appetite and trillions of dollars at its disposal, the private equity industry is now buying everything from your opioid treatment center to that helicopter that helps swoop you up from a car crash site. It may even control how and when you caTable of ContentsAcknowledgmentsIntroduction. Hiding in Plain SightChapter 1. Who Even Are They? Private Equity from Soup to NutsChapter 2. The Emergence of the Alternative Asset ClassChapter 3. Consolidating Health CareChapter 4. It's between Me and My Doctor?Chapter 5. Drilling for Gold: Corralling DentistsChapter 6. Frail Elderly and Children: Homecare and HospiceChapter 7. Public Crisis, Private Gain: Substance Abuse and Eating DisordersChapter 8. Capitalizing on Children with Autism Spectrum DisordersChapter 9. Hijacking an Industry: Medical Ambulances and Emergency Air TransportConclusion. Infiltrating Our Health Care SystemAppendix. Selected Private Equity Firms Buying Health Care BusinessesAbbreviationsGlossaryNotesBibliography Index

    7 in stock

    £26.10

  • My Quest for Health Equity

    Johns Hopkins University Press My Quest for Health Equity

    15 in stock

    Book SynopsisReading this book is like sitting down with Dr. David Satcher to hear stories of leadership and lessons learned from his lifetime commitment to health equity. Dr. David Satcher is one of the most widely known and well-regarded physicians of our time. A former four-star admiral in the US Public Health Service Commissioned Corps, he served as the assistant secretary for health, the surgeon general of the United States, and the director of the Centers for Disease Control and Prevention before founding the eponymous Satcher Health Leadership Institute at Morehouse School of Medicine. At the core of his impact on public health, he is also a lifelong leader for civil rights and health equity. Born black and poor in the deep South, Dr. Satcher was a victim of an unjust health care system: he almost died of whooping cough at the age of two because Jim Crow laws meant that his black doctor could not admit him to a hospital. That experience was the first of many that shaped him as a leader andTable of ContentsAcknowledgments IntroductionChapter 1. Lessons Learned from Fifty Years of Leadership Chapter 2. From Health Disparities to Global Health Equity Chapter 3. When Leadership Confronts FailureChapter 4. The Need for Clear CommunicationChapter 5. The Need for Continual Learning Chapter 6. A Three-Dimensional Perspective on Leadership Chapter 7. Discipline in the Quest for Health Equity Chapter 8. Leading from Science to Policy to PracticeChapter 9. Confronting the Epidemic of Overweight and ObesityChapter 10. The Advancement of Reproductive HealthChapter 11. Overcoming the Stigma of Mental Health ProblemsChapter 12. Leadership beyond ExpertiseChapter 13. The Team Approach to LeadershipChapter 14. Leading for Institutional Sustainability Frequently Used AcronymsReferencesIndex

    15 in stock

    £17.10

  • Quarantine

    Johns Hopkins University Press Quarantine

    5 in stock

    Book SynopsisThis riveting story of the typhus and cholera epidemics that swept through New York City in 1892 has been updated with a new preface that tackles the COVID-19 pandemic. Winner, 2003 Arthur J. Viseltear Prize for Outstanding Book in the History of Public Health, American Public Health AssociationIn Quarantine! Howard Markel traces the course of the typhus and cholera epidemics that swept through New York City in 1892. The story is told from the point of view of those involvedthe public health doctors who diagnosed and treated the victims, the newspaper reporters who covered the stories, the government officials who established and enforced policy, and, most importantly, the immigrants themselves. Drawing on rarely cited stories from the Yiddish American press, immigrant diaries and letters, and official accounts, Markel follows the immigrants on their journey from a squalid and precarious existence in Russia's Pale of Settlement, to their passage in steerage, to New York's Lower East Table of ContentsFigures and Tables Preface to the First EditionPreface to the Updated Edition: Revisiting Quarantine!Introduction: The Concept of QuarantinePart I. Averting a PestilenceThe Typhus Fever Epidemic on New York's Lower East SideChapter 1. The Russian Jews of the SS MassiliaChapter 2. The City Responds to the Threat of TyphusChapter 3. The Results of the Quarantine Part II. "Cholera May Knock, but It Won't Get In!"Cholera, Class, and Quarantine in New York HarborChapter 4. Awaiting the Cholera: "Choleria!"Chapter 5. "Knocking Out the Cholera!"Part III. Legislating QuarantineAttempting to Restrict Immigration as a Cholera PreventiveChapter 6. Maintaining the QuarantineChapter 7. The Doctors' Prescription for QuarantineChapter 8. The Congress RespondsEpilogue: "The Microbe as Social Leveller"NotesIndex

    5 in stock

    £23.75

  • Curriculum Development for Medical Education

    Johns Hopkins University Press Curriculum Development for Medical Education

    Book SynopsisA thoroughly revised and updated fourth edition of a text that has become an international standard for curriculum development in health professional education. Intended for faculty and other content experts who have an interest or responsibility as educators in their discipline, Curriculum Development for Medical Education has extended its vision to better serve a diverse professional and international audience. Building on the time-honored, practical, and user-friendly approach of the six-step model of curriculum development, this edition is richly detailed, with numerous examples of innovations that challenge traditional teaching models. In addition, the fourth edition presents updates in our understanding of how humans learn; a new chapter on curricula that address community needs and health equity; and an increased emphasis throughout on health systems science, population health, equity, educational technology in health professions education, and interprofessional education. Table of ContentsPrefaceList of ContributorsIntroductionPatricia A. Thomas and David E. KernOne. Overview: A Six-Step Approach to Curriculum DevelopmentDavid E. KernTwo. Step 1: Problem Identification and General Needs AssessmentBelinda Y. ChenThree. Step 2: Targeted Needs AssessmentMark T. HughesFour. Step 3: Goals and ObjectivesPatricia A. ThomasFive. Step 4: Educational StrategiesSean A. Tackett and Chadia N. AbrasSix. Step 5: ImplementationMark T. HughesSeven. Step 6: Evaluation and FeedbackBrenessa M. Lindeman, David E. Kern, and Pamela A. LipsettEight. Curriculum Maintenance and EnhancementDavid E. Kern and Patricia A. ThomasNine. DisseminationDavid E. Kern and Sean A. TackettTen. Curriculum Development for Larger ProgramsPatricia A. Thomas and David E. KernEleven. Curricula That Address Community Needs and Health EquityHeidi L. Gullett, Mamta K. Singh, and Patricia A. ThomasAppendix A. Example CurriculaTopics in Interdisciplinary Medicine: High-Value Health CareAmit K. PahwaNeurology Graduate Training Program in ZambiaDeanna SaylorThe Kennedy Krieger Curriculum: Equipping Frontline Clinicians to Improve Care for Children with Behavioral, Emotional, and Developmental DisordersMary L. O'Connor LeppertAppendix B. Curricular, Faculty Development, and Funding ResourcesPatricia A. Thomas and David E. KernIndex

    £79.00

  • The Caregivers Guide to Memory Care and Dementia

    Johns Hopkins University Press The Caregivers Guide to Memory Care and Dementia

    Book SynopsisThis practical guide provides general caregiving tips and helps you decide when and how to transition your loved one to a dementia care community. Caring for someone with dementia is challenging, especially when it comes time to think about other living arrangements. What do you need to know about dementia, including its different stages? What do you do if the person you're caring for seems to have trouble recognizing you? When is it time to move a person living with dementia into a senior living community? And how can you maintain your relationship with your loved one when you are living apart?Gerontologist and dementia care consultant Rachael Wonderlin has written a compassionate book to help friends and family members of those living with dementia answer these tough questionsand more. In practical, down-to-earth language, The Caregiver's Guide to Memory Care and Dementia Communities walks the reader through key points about dementia care, including common terminology used by healTable of ContentsForeword, by Michelle TristaniPart I. Defining and Understanding DementiaChapter 1. Why This Book Is Worth ReadingChapter 2. What Is Dementia?Chapter 3. Causes of DementiaChapter 4. Stages of DementiaChapter 5. MedicationsPart II. Communicating with People Living with DementiaChapter 6. Embracing Someone's RealityChapter 7. Why Logic, Quizzing, and Reorientation Don't WorkChapter 8. Yes, and . . . : Improvisation and DementiaChapter 9. Communicating with Someone Experiencing Hallucinations and DelusionsChapter 10. Helping with Timeline ConfusionChapter 11. Personal PreferencesChapter 12. Becoming a Dementia DetectiveChapter 13. AphasiaPart III. Caregiver Stress and Choosing a Care CommunityChapter 14. Caregiving StressChapter 15. Guilt and Taking Things AwayChapter 16. How to Handle Family Dynamics When Choosing a Care CommunityChapter 17. Myths about Care CommunitiesChapter 18. At-Home SafetyChapter 19. When Is It Time to Move Your Loved One?Chapter 20. What Types of Communities Exist?Chapter 21. Cost of CarePart IV. Caregiving in a Care CommunityChapter 22. What to Expect at a Dementia Care CommunityChapter 23. Move-In DayChapter 24. Remember That Caregiving Is an Imperfect ScienceChapter 25. Visiting and Saying GoodbyeChapter 26. Day Trips and OutingsChapter 27. ActivitiesChapter 28. Building a Dementia-Friendly EnvironmentPart V. Changes in CareChapter 29. When Technology Works and When It Doesn't Chapter 30. When It's Time for a Dietary ChangeChapter 31. Friendships and Disagreements among ResidentsChapter 32. Sex and Sexual OrientationChapter 33. When It's Time for HospiceChapter 34. When There's a Hospital TripChapter 35. Final Thoughts and NotesAppendix. Clinical Dementia Rating ScaleIndex

    £18.00

  • The Contagion of Liberty

    Johns Hopkins University Press The Contagion of Liberty

    10 in stock

    Book SynopsisNow an LA Times Book Prize finalist: a timely and fascinating account of the raucous public demand for smallpox inoculation during the American Revolution and the origin of vaccination in the United States. Finalist of the LA Times Book Prize for History by the LA Times, Winner of the Peter J. Gomes Memorial Book Prize by the Massachusetts Historical SocietyThe Revolutionary War broke out during a smallpox epidemic, and in response, General George Washington ordered the inoculation of the Continental Army. But Washington did not have to convince fearful colonists to protect themselves against smallpoxthey were the ones demanding it. In The Contagion of Liberty, Andrew M. Wehrman describes a revolution within a revolution, where the violent insistence for freedom from disease ultimately helped American colonists achieve independence from Great Britain. Inoculation, a shocking procedure introduced to America by an enslaved African, became the most sought-after medical procedure of thTrade ReviewIn The Contagion of Liberty, historian Andrew Wehrman traces the path of the smallpox-inoculation movement, and its generally overlooked impact on politics around the American War of Independence. He argues that smallpox influenced the journey towards independence from British rule, and how Americans conceived of their new, hard-won liberties. It is a tale of startling contemporary relevance.As vaccination was privatized, he argues, the concept of a civic duty to protect public health was displaced by the idea of disease as a consequence of personal negligence.—NatureThe Covid pandemic wasn't the first time that America has found itself split along ideological seams over infectious disease.As historian Andrew Wehrman explains in The Contagion of Liberty: The Politics of Smallpox in the American Revolution, our downright violent resistance to, and demand for freedom from, the disease was also precisely what helped galvanize our mobilization of independence from England.—EngadgetThe Contagion of Liberty is a timely and fascinating account of the raucous public demand for smallpox inoculation during the American Revolution.This thought-provoking history offers a new dimension to our understanding of both the American Revolution and the origins of public health in the United States.—New York AlmanackIn The Contagion f Liberty, Andrew Wehrman weaves together dozens of individual stories and their layered historical contexts to provide a fascinating account of smallpox in America, from colonial times through the early republic. A deeply researched and gracefully written volume.—Wall Street JournalTimely and thought provoking.—H-NetOver the past three years of the COVID-19 pandemic, controversies about preventive measures, government versus individual control of health, medical racism and health inequities, disease versus the economy, and vaccine mandates have raged. Wehrman shows that this is not new ground we are treading...—American Journal of Public HealthAndrew Wehrman makes a robust case that there is nothing new under the sun in public health in his fantastic new monographThe Contagion of Liberty is both timely and sturdy in its findingsIt belongs on any list of the best history books of 2023.—American HistoryAn accessible and valuable example of the long history of American healthcare controversies.—H-WarThe Contagion of Liberty is a well-argued and extremely timely book. The depth of research and attention to political as well as medical debates make it a rare successful crossover text of interest to both historians of medicine and historians of the American Revolution. The strength and clarity of the argument and variety of evidence brought to bear make this book a must-read for students and scholars of the period. Wehrman demonstrates that the history of health and disease are essential—not supplemental—to our understanding of the past.—Journal of the History of Medicine and Allied SciencesWell written and engaging....Rather than positioning epidemics and disease as natural phenomenon existing next to social and cultural questions, as most histories of that period do, [Wehrman] convincingly shows that smallpox and inoculation were part of political debates and ideas flowing through the history of the United States' independence....As recent epidemiological and political challenges of the present and recent past remind us, and as Wehrman aptly illuminates, these debates remain as pertinent today as they were in 1776.—H-Soz-KultTable of ContentsIntroductionChapter 1. Sore Spots: Making Inoculation AmericanChapter 2. General Inoculation in BostonChapter 3. The Norfolk RiotsChapter 4. The Siege of Castle PoxChapter 5. Creating a Critical MassChapter 6. From Rumors to RemediesChapter 7. George Washington's About-FaceChapter 8. Thirteen ScarsChapter 9. Inoculation NationChapter 10. Vaccination PainsConclusionAcknowledgementsNotesIndex

    10 in stock

    £23.85

  • Building Breakthroughs

    Johns Hopkins University Press Building Breakthroughs

    Book SynopsisFrom mRNA vaccines to gene therapies, the next frontier of medical innovation is here. In Building Breakthroughs, Raju Prasad tells the story of important advancements in biotechnology and medical innovation from gene therapies to mRNA vaccines, providing historical context and examining cutting-edge research. Based on in-depth interviews with both the scientists who developed these discoveries and the patients who have benefited from them, Building Breakthroughs reveals the key players behind drug development and the inner workings of this essential business. Through stories of patients and their families, and of the researchers creating new treatments, Prasad reveals how cell therapies are advancing to treat childhood leukemia and a form of lymphoma, how a gene therapy was established to treat the rare disease spinal muscular atrophy type I, and potentially curative therapies that are being developed for sickle cell disease. By examining the clinical trial and regulatory paths eachTable of ContentsIntroductionPart I. The Journey from Idea to ApprovalChapter 1. Leukemia and LymphomaChapter 2. Chimeric Antigen Receptor (CAR)-T Cell TherapyChapter 3. Spinal Muscular AtrophyChapter 4. In Vivo Gene TherapyChapter 5. Sickle Cell AnemiaChapter 6. Ex Vivo Gene-Modified Cell TherapyChapter 7. A Brief History of FDA RegulationChapter 8. The Path to ApprovalPart II. Enabling the Next Wave Of InnovationChapter 9. Building Blocks Chapter 10. Recognizing ValueChapter 11. Financial and Human Capital Investments in BiotechnologyChapter 12. Looking ForwardEpilogue. COVID-19AcknowledgmentsReferencesIndex

    £20.70

  • Well Connected

    Johns Hopkins University Press Well Connected

    1 in stock

    Book SynopsisHow a community in Cairo, Egypt, has adapted the many systems required for clean water. Who is responsible for ensuring access to clean potable water? In an urbanizing planet beset by climate change, cities are facing increasingly arid conditions and a precarious water future. In Well Connected, anthropologist Tessa Farmer details how one community in Cairo, Egypt, has worked collaboratively to adapt the many systems required to facilitate clean water in their homes and neighborhoods. As a community that was originally not included in Cairo's municipal systems, the residents of Ezbet Khairallah built their own potable water and wastewater infrastructure. But when the city initiated a piped sewage removal system, local residents soon found themselves with little to no power over their own water supply or wastewater removal. Throughout this transition, residents worked together to collect water at the right times to drink, bathe, do laundry, cook, and clean homes. These everyday pracTable of Contents1. Introduction2. Sowing Connection3. Locating Connection4. Hedging Connection5. Sensing Connection6. Conclusion: Gathering ConnectionReferencesIndex

    1 in stock

    £37.35

  • The Present Illness

    Johns Hopkins University Press The Present Illness

    3 in stock

    Book SynopsisBeyond political posturing and industry quick-fixes, why is the American health care system so difficult to reform?Health care reform efforts are difficult to achieve and have been historically undermined by their narrow scope. In The Present Illness, Martin F. Shapiro, MD, PhD, MPH, weaves together history, sociology, extensive research, and his own experiences as a physician to explore the broad range of afflictions impairing US health care and explains why we won''t be able to fix the system without making significant changes across society. With a sharp eye and ready humor, Shapiro dissects the ways all groups participatingclinicians and their organizations, medical schools and their faculty, hospitals and clinical corporations, scientists and the National Institutes of Health, insurers and manufacturers, governments and their policies, and also patients and the publicshape and reinforce a dysfunctional system. Shapiro identifies three major pr

    3 in stock

    £22.50

  • Building a Unified American Health Care System

    Johns Hopkins University Press Building a Unified American Health Care System

    20 in stock

    Book Synopsis

    20 in stock

    £29.70

  • Fatal Jump

    Johns Hopkins University Press Fatal Jump

    4 in stock

    Book SynopsisExploring the fateful chains of events that gave rise to humanity's infectious diseases and pandemics. Why do global pandemics materialize? To address this question, we must delve into the world of pathogens that transcend their original host species and jump into new ones. Most pathogens fail to initiate infection or spread in the population when they jump. Only a few sustain onward chains of transmission, and even fewer sustain these indefinitely. Yet the rare pathogens that do make the leap have caused many of humanity's most dangerous infectious diseases. In Fatal Jump: Tracking the Origins of Pandemics, veterinary disease ecologist Dr. Leslie Reperant investigates mysteries such as how African-originated monkeypox left its home continent, why COVID-19 could threaten measles control, and how pigs' fondness for mangoes enabled the deadly Nipah virus to spread. She shares behind-the-scenes insights into hugely destructive pathogens carried by rats, bats, ticks, and mosquitoes, as

    4 in stock

    £24.75

  • Lazaretto

    Johns Hopkins University Press Lazaretto

    10 in stock

    Book Synopsis

    10 in stock

    £27.55

  • Healing the Traumatized Brain

    Johns Hopkins University Press Healing the Traumatized Brain

    4 in stock

    Book SynopsisTable of ContentsAcknowledgmentsIntroductionPart I: Brain Structure and Function1. The Inner Workings of the Brain2. The Structure of the Brain3. Types of Brain Injury4. Influences on Recovery after Brain InjuryPart II: Neural Plasticity5. The Idea of Plasticity6. Neuroplasticity and Recovery from Brain Injury7. Behavioral Therapy and Plasticity8. Stress Management and Plasticity9. Cognitive Rehabilitation and Plasticity10. Nutrition and PlasticityPart III: Emotional Problems Caused by the Traumatized Brain11. Depression and the Traumatized Brain12. Mania and the Traumatized Brain13. Anxiety and the Traumatized Brain14. PTSD and the Traumatized BrainPart IV: Behavioral Disorders Caused by the Traumatized Brain15. Psychosis and the Traumatized Brain16. Aggression and the Traumatized Brain17. Impulsivity and the Traumatized Brain18. Substance Use and The Traumatized Brain19. Apathy and the Traumatized Brain20. Sleep and the Traumatized BrainPart V: Cognitive Issues Caused by the Traumatized Brain21. Attention and the Traumatized Brain22. Memory and the Traumatized Brain23. Executive Function and the Traumatized Brain24. Language and the Traumatized BrainPart VI: The Traumatized Brain and the Other Symptoms25. Headaches and the Traumatized Brain26. Seizures and the Traumatized Brain27. Vision and the Traumatized Brain28. Balance and the Traumatized Brain29. Hormonal Abnormalities and the Traumatized BrainPart VII: The Traumatized Brain and the Future30. Repeated Brain Injuries31. Future Treatments: Brain Stimulation and PlasticityEpilogueGlossaryResourcesSuggested ReadingIndex

    4 in stock

    £40.95

  • Healing the Traumatized Brain

    Johns Hopkins University Press Healing the Traumatized Brain

    Book SynopsisThe essential guide to recovering from concussion and other brain injuries. Recovering from a brain injury can be a challenging and prolonged process. Learn how to maximize your recovery from the effects of brain injuries with the guidance of Sandeep Vaishnavi, MD, PhD, and Vani Rao, MBBS, MD, two leading medical experts with extensive experience helping patients recover from concussion and other brain injuries. Healing the Traumatized Brain explains how the brain works, how injuries affect the brain, and how to use your brain's own power to recover. This detailed guide contains essential information on: The emotional, behavioral, mental, and physical effects following concussion and other brain injuries Medication options and lifestyle changes Practical strategies for healing, including stress management, behavioral therapy, and cognitive rehabilitation Neuroplasticity and nutrition as they affect recovery Behavioral disorders, balance disorders, and hormonal changes following concuTable of ContentsAcknowledgmentsIntroductionPart I: Brain Structure and Function1. The Inner Workings of the Brain2. The Structure of the Brain3. Types of Brain Injury4. Influences on Recovery after Brain InjuryPart II: Neural Plasticity5. The Idea of Plasticity6. Neuroplasticity and Recovery from Brain Injury7. Behavioral Therapy and Plasticity8. Stress Management and Plasticity9. Cognitive Rehabilitation and Plasticity10. Nutrition and PlasticityPart III: Emotional Problems Caused by the Traumatized Brain11. Depression and the Traumatized Brain12. Mania and the Traumatized Brain13. Anxiety and the Traumatized Brain14. PTSD and the Traumatized BrainPart IV: Behavioral Disorders Caused by the Traumatized Brain15. Psychosis and the Traumatized Brain16. Aggression and the Traumatized Brain17. Impulsivity and the Traumatized Brain18. Substance Use and The Traumatized Brain19. Apathy and the Traumatized Brain20. Sleep and the Traumatized BrainPart V: Cognitive Issues Caused by the Traumatized Brain21. Attention and the Traumatized Brain22. Memory and the Traumatized Brain23. Executive Function and the Traumatized Brain24. Language and the Traumatized BrainPart VI: The Traumatized Brain and the Other Symptoms25. Headaches and the Traumatized Brain26. Seizures and the Traumatized Brain27. Vision and the Traumatized Brain28. Balance and the Traumatized Brain29. Hormonal Abnormalities and the Traumatized BrainPart VII: The Traumatized Brain and the Future30. Repeated Brain Injuries31. Future Treatments: Brain Stimulation and PlasticityEpilogueGlossaryResourcesSuggested ReadingIndex

    £18.45

  • Health Plans Unmasked

    Johns Hopkins University Press Health Plans Unmasked

    10 in stock

    Book SynopsisAn insightful overview of health insurers and a guide to sustainability for provider organizations. Physicians experience ongoing frustrations in their relationships with health plans. Even as they struggle to keep up with accelerating clinical advances, they face daunting challenges from payers that are transitioning from traditional fee-for-service contracts to complex alternative payment models. In Health Plans Unmasked, Martin Lustick, MD, offers insights and guidance for those who face the herculean task of transforming their business practices to achieve financial stability while improving outcomes for their patients. By explaining both how and why insurance companies behave the way they do, Dr. Lustick helps providers avoid mistakes and take advantage of opportunities for success. He provides information on: The evolution of health care financing in the United States The nuts and bolts of health plan capabilities and the real motives of health plan administrators Tips for suTable of ContentsForewordAcknowledgmentsSection 1: The Basics1. Historical Context2. What is a Health Plan?3. Medicare4. Medicaid5. Commercial Insurance6. Brokers and ConsultantsSection 2: Reimbursement Basics7. The ABCs of Fee for Service8. What Happens to a Claim?9. Payment Errors10. Health Plan Strategic Concerns11. Analytics12. Cost Management Strategies13. Quality14. Care Management15. Health Plan CommitteesSection 3: Contracting16. Health Plan Contracting 10117. Value-Based Budgeting18. Incentive Payments19. Risk MitigationSection 4: Opportunities and Obstacles in Value-Based Care20. Price Transparency21. Subrogation22. Pharmacy Benefit Management23. On Becoming a PayviderSection 5: A Shifting Paradigm24. Closing ThoughtsGlossary of AcronymsIndex

    10 in stock

    £37.35

  • Death in Custody

    Johns Hopkins University Press Death in Custody

    15 in stock

    Book SynopsisThe United States significantly undercounts the number of people who die in law enforcement custody each year. How can we fix this?Deaths resulting from interactions with the US criminal legal system are a public health emergency, but the scope of this issue is intentionally ignored by the very systems that are supposed to be tracking these fatalities. We don't know how many people die in custody each year, whether in an encounter with police on the street, during transport, or while in jails, prisons, or detention centers. In order to make a real difference and address this human rights problem, researchers and policy makers need reliable data. In Death in Custody, Roger A. Mitchell Jr., MD, and Jay D. Aronson, PhD, share the stories of individuals who died in custody and chronicle the efforts of activists and journalists to uncover the true scope of deaths in custody. From Ida B. Wells's enumeration of extrajudicial lynchings more than a century ago to the Washington Post's current eTrade ReviewDeath in Custody is a radical shift in how to analyze violence, misconduct, and dysfunction in the criminal justice system in the modern era.Aronson and Mitchell offer recommendations for attempting to sort out this crisis, but this book would be important even if it didn't. Death in Custody makes the case that white supremacy, economic inequality, and exploitation are among the causes of this festering problem.—The ProgressiveDeath in Custody provides readers with the brutal history on which the U.S. criminal legal system was built.These unnecessary deaths will continue to occur until there is a uniform way of making our judicial system transparent and accountable.—ZEKE magazineIn Death in Custody, Roger A. Mitchell Jr. and Jay D. Aronson argue that deaths in law enforcement custody amount to a public health emergency. Their work ties in high-profile examples and shows how journalists have long done the work of tracking in-custody deaths.Mitchell and Aronson argue that collecting accurate data is the first step toward addressing this crisis.—Chris BlackwellThere's no real way to know how many people die in custody each year. In their book, Death in Custody, Roger and Jay chronicle the efforts of activists and journalists to uncover the true scope of this problem, to try to figure out how many people actually are dying in custody. And they argue for a straightforward solution. I learned a lot from this book. It blew my mind.—DeRay McKesson, Pod Save the PeopleDr. Mitchell and Professor Aronson's meticulous examination of our criminal legal system is a shocking exposure of just how little our society knows or cares to know about people dying in custody. In their careful accounting of various attempts to understand and prevent deaths in custody, one thing becomes clear: the reforms on the margins that federal, state, and local governments engage in are simply not enough to stop the human suffering that occurs every day in this country.—Hunter Parnell, Public Defenseless PodcastDeeply researched.—AZ LuminariaIn a striking collaboration, Roger A. Mitchell (a pathologist) and Jay D. Aronson (a human rights expert) expose an underappreciated problem at the intersection of public health and criminal justice: People who die in police custody are often unaccounted for. By combining perspectives ranging from historical analysis to contemporary methods in public health and statistics, the authors highlight a gap that reveals major challenges in the criminal legal system and in our public health infrastructure.—Harvard Public Health, "Best Public Health Books of 2023"In their courageous and often gripping book Death in Custody, Roger A. Mitchell (a pathologist) and Jay D. Aronson (a human rights expert) teach us that the process through which deaths are counted or characterized is a justice issue in and of itself.—C. Brandon Ogbunu, Harvard Public HealthNo one really knows exactly how many people across the country die in jails and prisons each year. This intricate investigation by Aronson and Mitchell details how things came to be this way.—Los Angeles TimesTable of ContentsIntroduction1. Lynching2. Early Advocacy Against Police Killings3. The Death in Custody Reporting Act4. Before Sandra Bland: Custodial Deaths in Texas5. Mortality Behind Bars: Documenting Deaths in Prisons, Jails, and Detention Centers6. Homicide: Death at the Hands of Another7. The Checkbox and BeyondIndex

    15 in stock

    £21.60

  • Collapse and Resiliency

    Johns Hopkins University Press Collapse and Resiliency

    3 in stock

    Book SynopsisAn insider account of how an African public health leader responded to an unprecedented Ebola outbreak. Tolbert Nyenswah, LLB, MPH, DrPH, was the assistant minister of health and deputy chief medical officer in Liberia when the 2014 Ebola epidemic struck. Nyenswah, the incident manager who led the response, became known as the Ebola Czar for his pivotal role in combating the epidemic despite his government's lack of resources. His story underscores the public health strategies that succeeded and those that failed, highlighting important lessons in managing current and future outbreaks. In Collapse and Resiliency, Nyenswah presents an insider's view of Liberia's response to the deadly Ebola epidemic. Nyenswah describes the fascinating journey from his childhood in a rural Liberian village to leading his country's response to the deadly outbreak, providing a deeply personal account of how the epidemic was finally controlled despite a depleted health care system. Prior to the Ebola epidTable of ContentsForewordEllen Johnson Sirleaf, Former President, Republic of LiberiaPrefaceIntroductionChapter 1. Ebola Hits LiberiaChapter 2. Born for Such a TimeChapter 3. Unsafe Rituals, Burial Practices, and International SpreadChapter 4. A Refugee in Côte d'IvoireChapter 5. Total Collapse of Public Health Care ServicesChapter 6. Security Challenge: Community Distrust and Resistance—West PointChapter 7. Interventions: What We Did and How We Did ItChapter 8. The International ResponseChapter 9. Recovery, Rebuilding, and ResiliencyChapter 10. ReflectionsAcronyms and AbbreviationsReferencesIndex

    3 in stock

    £26.10

  • Nothing But Nets

    Johns Hopkins University Press Nothing But Nets

    2 in stock

    Book SynopsisTable of ContentsList of AbbreviationsIntroduction: Making Evidence-Based Global Health in Africa1. The Scientific Object: Becoming the Right Tool for the Job2. The Biomedical Technology: From Kenyan Particulars to Global Universals3. The Technology of Neoliberal Policy: Taking Insecticide-Treated Nets to Market4. The Global Health Commodity: Selling the Value of Saving Lives5. The Domestic Technology: Making Healthy Homes in KenyaConclusion: Lessons for Global Health and Malaria Control in a Precarious AgeAcknowledgementsBibliographyIndexNotes

    2 in stock

    £37.35

  • Viruses and Reproductive Injustice

    Johns Hopkins University Press Viruses and Reproductive Injustice

    1 in stock

    Book SynopsisBrazil's Zika outbreak revealed extreme health disparities and reproductive injustice across racial and socioeconomic lines. Brazil's 2015 Zika outbreak led to severe illnesses for many and the birth of several thousands of children with severe brain damage. Even though mosquito-borne diseases such as the Zika virus affect people across society, these children were born almost exclusively to poor, and usually non-white, women. In Viruses and Reproductive Injustice, Ilana Löwy explores the complicated health disparities and reproductive injustice that led to these cases of congenital Zika syndrome. Löwy examines the history of the outbreak in Brazil and connects it to broader questions concerning reproductive rights, the medical science behind understanding new pathogens, and the role of international health organizations in battlingor ignoringpublic health crises. The explanation behind the strongly skewed distribution of cases among social classes was far from straightforward or oTable of ContentsContentsPreface: A Forgotten Virus and Expunged MemoriesAcknowledgmentsIntroduction. Framing an EpidemicChapter 1. Viruses and Mosquitoes: From Yellow Fever to ZikaChapter 2. Fetuses: Women, Doctors, and the LawChapter 3. Surprises: "I've never seen anything like this"Chapter 4. Zika in Brazil: Producing Partial KnowledgeChapter 5. Stratified Reproduction: Class, Ethnicity, and RiskChapter 6. Mães de Micro: Zika and Maternal CareChapter 7. After Zika: Open Questions, Complex LegacyConclusion. Embodied InequalityFurther ReadingNotesIndex

    1 in stock

    £42.50

  • The Liberty Paradox

    Johns Hopkins University Press The Liberty Paradox

    7 in stock

    Book SynopsisHow do we balance freedom with the responsibilities we owe each other as members of society?Are we free to do whatever we want? This idea challenges us throughout our daily lives, from how to tackle pandemic restrictions and vaccine mandates to how to respond to technological innovations and climate change warnings. In The Liberty Paradox, David Kinley argues that we must rehabilitate the notion of liberty by rescuing it from the myopic demands of freedom without limit and reinstating the essential ingredient of social responsibility. Combining political, philosophical, and personal reflections as a global human rights lawyer, Kinley examines the implications of this liberty reset for how we negotiate freedom's boundaries in the realms of wealth, work, health, happiness, security, voice, love, and death. With chapters dedicated to each of these life-defining domains and written in a style both engaging and insightful, The Liberty Paradox explores how we tryand often failto balance pers

    7 in stock

    £22.50

  • The Rich Flee and the Poor Take the Bus

    Johns Hopkins University Press The Rich Flee and the Poor Take the Bus

    20 in stock

    Book Synopsis

    20 in stock

    £24.75

  • Progress Notes

    Johns Hopkins University Press Progress Notes

    15 in stock

    Book SynopsisA groundbreaking approach to training doctors could transform the future of health care. For decades, physicians have been trained on the textbook of the body, from the corpse in a cadaver lab to the patient in a procedure suite. This type of training usually leads them to specialize in specific organs or systems and breeds an increasingly impersonal view of medicine in which the importance of person-to-person carethe hallmark of a good relationship between doctors and patientshas been lost. In this engrossing narrative, you'll meet seven extraordinary students who embarked on a new way to train doctors that attempts to regain what's been lost. These medical students follow patients instead of physicians, accompanying patients to primary care appointments, emergency room visits, and even surgical procedures, developing deep connections and understanding the intricate interplay between the health of our bodies and the health of our communities. They learn the textbook of a community

    15 in stock

    £22.50

  • In These Streets

    Johns Hopkins University Press In These Streets

    20 in stock

    Book SynopsisA groundbreaking expose on the rise of gun violence in recent years. Journalist Josiah Bates pulls back the curtain on a crisis that continues to plague the United States in this gripping narrative. Fueled by the convergence of the COVID-19 pandemic and social unrest, gun violence has surged to unprecedented levels, devastating marginalized communities and urban areas across the nation. Bates embarks on a heart-wrenching journey, crisscrossing the country to meet victims, perpetrators, community activists, and renowned scholars. Through their powerful stories, he unearths the hidden causes behind the escalating gun violence epidemic. From the corrosive effects of poverty to the contentious debates surrounding policing and calls to defund law enforcement, Bates fearlessly navigates the intricate web of factors influencing gun violence. Through firsthand accounts and expert analysis, he exposes the systemic failures that perpetuate this cycle of destruction and delivers a powerful clar

    20 in stock

    £21.85

  • One Health and the Politics of COVID19

    Johns Hopkins University Press One Health and the Politics of COVID19

    15 in stock

    Book SynopsisUnpacks the mysteries of COVID-19''s origins to impart important lessons for future outbreaks.Unpacking the mysteries of COVID-19''s origins to impart important lessons for future outbreaks.In this timely book, leading public health expert Laura H. Kahn uses the comprehensive One Health approach to investigate the COVID-19 pandemic. The concept of One Health recognizes the interconnected links among the health of humans, animals, plants, and the environment. By comparing the history, science, and clinical presentations of three different coronavirusesSARS-CoV-1, MERS, and SARS-CoV-2 (COVID-19)Kahn uncovers insights with important repercussions for how to prepare for and avoid future pandemics. The One Health approach is a useful framework for examining the outbreak of COVID-19. Understanding the origins of this zoonotic disease requires examining the environmental and molecular biological factors that allowed the virus to spread to humans. Kahn inv

    15 in stock

    £24.75

  • Well Fight It Out Here

    Johns Hopkins University Press Well Fight It Out Here

    1 in stock

    Book SynopsisHow a coalition of Black health professions schools made health equity a national issue.Winner of the Phillis Wheatley Award from the Sons & Daughters of the United States Middle PassageRacism in the US health care system has been deliberately undermining Black health care professionals and exacerbating health disparities among Black Americans for centuries. These health disparities only became a mainstream issue on the agenda of US health leaders and policy makers because a group of health professions schools at Historically Black Colleges and Universities banded together to fight for health equity. We''ll Fight It Out Here tells the story of how the Association of Minority Health Professions Schools (AMHPS) was founded by this coalition and the hard-won influence it built in American politics and health care. David Chanoff and Louis W. Sullivan, former secretary of health & human services, detail how the struggle for equity has been fought in the field Trade ReviewAn important, detailed account of the hard-won victories in the fight for equal health care access in the United States.—Foreword ReviewsRacism in the U.S. health care system has been deliberately undermining Black health care professionals and exacerbating health disparities among Black Americans for centuries.David Chanoff and Louis W. Sullivan, former secretary of Health and Human Services, detail how the struggle for equity has been fought in the field of health care, where bias and disparities continue to be volatile national issues.—Washington InformerA pertinent and valuable exploration of the often-overlooked endeavors to address racial health disparities in the United States....The book captivates readers by weaving together political history and memoir, interspersed with interviews and reflections from those closely associated with AMPHS to paint a vivid picture of a critical historical period.—The FASEB JournalTable of ContentsPrefaceTimelineChapter 1. The Nadir Chapter 2. The Response Chapter 3. Abraham Flexner and the Black Medical Schools Chapter 4. AMHPS: The Founding Chapter 5. The Heckler Report Chapter 6. Landmark Legislation Chapter 7. AMHPS and the Secretary Chapter 8. The Office of Minority Health Chapter 9. The Center for Minority Health and Health Disparities Chapter 10. A National Institute Chapter 11. A Common Mission Afterword Acknowledgments Notes Index

    1 in stock

    £18.45

  • Asymptomatic

    Johns Hopkins University Press Asymptomatic

    3 in stock

    Book SynopsisThe riveting account of how asymptomatic transmission drove COVID-19''s global spread and catalyzed interventions to control it.Why was COVID-19 so difficult to contain and so devastating to people and economies worldwide? In Asymptomatic, author Joshua S. Weitz explains how silent transmission enabled COVID-19''s massive and tragic global impact. Weaving the science of viral infections together with an insider''s look at response efforts, Weitz guides readers through the shockwaves of successive epidemic waves as public health officials and academic research teams confronted the rise and risk of what was then a burgeoning global pandemic. The discovery of asymptomatic spread also fueled competing narratives: either COVID-19 was about to dissipate as quickly as it had emerged or completely disrupt life as we knew it. Weitz, a physicist-turned-biologist who directs a quantitative viral dynamics research group and has been immersed in COV

    3 in stock

    £26.10

  • Margin over Mission

    Johns Hopkins University Press Margin over Mission

    20 in stock

    Book Synopsis

    20 in stock

    £20.70

  • Governing How We Care

    Temple University Press,U.S. Governing How We Care

    Book SynopsisAn analysis of local struggles over community health as a window into governance, citizenship, and identity formation.Trade Review"[T]his is a thoughtful contribution to relationships between government, community, and public health... Recommended." Choice, September 2012 "Shaw offers a sophisticated critical examination of community health efforts in the United States... Shaw's book is interesting and provides an insightful critique of public health programming in the United States. She demonstrates both the contested nature of what these program[s] do and the definitions of the communities that they are intended to serve. The book will no doubt be of interest to sociologists, anthropologists, and other social scientists interested in societal responses to health problems. It is well written and deeply grounded in contemporary social theory and careful analysis of rich and varied ethnographic data...social theorists and ethnographers will find the book a valuable contribution to the field... Shaw's critique is clear and significant." Sociology of Health & Illness, November 2012 "This book is a must-read for policy makers, researchers, health care administrators, public officials, and others who are interested in the complex issues surrounding health care delivery in the United States... [Shaw] explores the risks and norms of drug prevention research... [Her] illumination of this phenomenon in the injection drug user population provides a challenging perspective to the field... Governing How We Care provides a concretely rooted lesson about the experience of vulnerable populations in public health programs. Readers will gain valuable insight into programs that aim to correct short-term behavior and long-term behavior adaptations." - Public Administration ReviewTable of ContentsContents Acknowledgments Introduction 1. The Governmentality of Community Health Part I: Technologies of Citizenship and Difference 2. Community Health Advocates: The Professionalization of "Like Helping Like" 3. Neoliberalism at Work: Contemporary Scenarios of Governmental Reforms in Public Health and Social Work 4. Technologies of Culturally Appropriate Health Care Part II: Technologies of Prevention and Boundaries of Citizenship: Drug Use, Research, and Public Health 5. "I Always Use Bleach": The Production and Circulation of Risk and Norms in Drug Research 6. Syringe Exchange as a Practice of Governing Conclusion References Index

    £64.80

  • The Statistical Analysis of Recurrent Events Statistics for Biology and Health

    Springer New York The Statistical Analysis of Recurrent Events Statistics for Biology and Health

    1 in stock

    Book SynopsisThis book presents models and statistical methods for the analysis of recurrent event data. More general intensity-based models are also considered, as well as simpler models that focus on rate or mean functions.Trade ReviewFrom the Reviews: "The book provides many good real life examples to demonstrate application of the methods discussed....[it] is excellent for teaching an advanced class in statistics on this topic as it also contains many good exercises at the end of each chapter, some being extensions of the discussions." (Journal of Biopharmaceutical Statistics (JBS), Issue #5, 2008) "This book provides a timely and comprehensive review of methodologies for recurrent event data analysis and should be beneficial to Biometrics readers who are interested in recurrent events." "The strength of this book is its scope. It covers most of the methodology that is readily available for general use. ...Overall, we think this is a very good reference for recurrent event data analysis, especially because no other books provide a similar degree of coverage, and it would provide a nice textbook for a graduate-level course on the topic." (Biometrics, September 2008) "This book deals with processes generating multiple events over time. … The book comprises eight chapters, four appendices and a useful notational glossary. … it is directed to a much broader target readership, like social scientists, economists and industrial statisticians as well. … Many examples are used to illustrate and discuss the models and statistical methods in great detail. Techniques for estimation, testing and model checking are lucidly described … for a graduate course." (Harald Heinzl, Zentralblatt MATH, Vol. 1159, 2009) “…Every aspiring statistical researcher interested in recurrent events should have this book on his/her shelf as a great guide for learning the state-of-the-art stochastic models, frequentist (mostly estimating equation and asymptotic based) methods, and computational tools (including popular programs and routines). This is a very well-organized and comprehensive book on a very rapidly expanding area of research. As a mentor of PhD students, I myself will definitely recommend every graduate student interested in mastering recurrent events to read this book thoroughly to understand the current state of the literature as well as areas of future research and further development.” ( Journal of the American Statistical Association, Dec. 2009, Vol. 104, No. 488)Table of ContentsModels and Frameworks for Analysis of Recurrent Events.- Methods Based on Counts and Rate Functions.- Analysis of Gap Times.- General Intensity-Based Models.- Multitype Recurrent Events.- Observation Schemes Giving Incomplete or Selective Data.- OtherTopics.

    1 in stock

    £74.99

  • Global Health Governance

    University of Toronto Press Global Health Governance

    Book SynopsisGlobalization has immersed all of humanity in a single germ pool. There are no health sanctuaries in a globalizing world. In Global Health Governance, Obijiofor Aginam explores the relevance of international law in contemporary public health diplomacy. He focuses on the concept of mutual vulnerability to explore the globalization of disease, in what is paradoxically a global village and a divided world. Drawing from a wide range of disciplines, Global Health Governance offers a holistic approach to global health governance involving a multiplicity of actors: nation-states, international organizations, civil society organizations, and private actors. Aginam articulates modest proposals under the rubric of communitarian globalism, a paradigm that strives to meet the ideals of 'law of humanity.' These proposals project a humane global health order where all of humanity is inexorably tied into a global compact and where the health of one nation-state rises and fa

    £25.19

  • Multidisciplinary Public Health

    Bristol University Press Multidisciplinary Public Health

    Book SynopsisA lively and comprehensive review of policy change, Multidisciplinary public health: Understanding the development of the modern workforce concludes with a reflection on the new public health system under way in England, making useful comparisons with the rest of the UK.Trade Review"Recent developments in public health are poorly understood by the public. Multidisciplinary public health provides a readable history, based on the authors' own involvement, of one key change in modern public health - the incorporation of non-medical people into the mainstream public health workforce." Virginia Berridge, London School of Hygiene and Tropical Medicine "Public health in England has moved into uncharted territory. This timely and important history of the changing workforce is an indispensable guide to the challenges and unfinished business ahead" David J Hunter, Durham University "A key text, entertainingly and expertly written, for anyone who wants to be better informed about public health and the contemporary development of the workforce that delivers it. This book provides a welcome addition to the literature on public health in England" Lord Hunt of King's HeathTable of ContentsIntroduction and methods; Developing the specialty of public health; The multidisciplinary public health movement of the 1990s; Changes for specialists I: Setting up a multidisciplinary public health senior appointments process; Changes for specialists II: The new regulatory system for specialists; Changes for specialists III: The establishment of multidisciplinary higher specialist training in public health; The focus on practitioners and the wider workforce; Where we are now? The new public health system in England from April 2013; Experience across the other UK countries; Conclusion.

    £77.39

  • Partnership Working in Public Health

    Bristol University Press Partnership Working in Public Health

    Book SynopsisPartnership working in public health presents the findings from a detailed study of public health partnerships in England which are used to explore the government's changes in public health now being implemented.Trade Review"The authors challenge the established view that partnership working is an effective way to tackle complex public health problems...and prompt the reader to consider a great array of factors that will challenge your preconceptions in considering a seemingly straightforward question." Research Policy and Practice"In this challenging volume David Hunter and Neil Perkins build on a diverse array of ideas and evidence about partnerships, taking the reader beyond simple descriptions to explore the theoretical basis of partnership and examples of what makes for success." Professor Gareth Williams, School of Social Sciences, Cardiff University."A timely and important analysis! As health systems are transformed in the UK and elsewhere, deeper understanding of complexity and how government enables or constrains innovation and change is critical." Allan Best, InSource Research Group"The book achieves its aim of using research to explore public health partnerships and their ability to deliver better health outcomes... there is little available for the intended audience on public health partnerships and the book challenges the widely held views that partnerships deliver demonstrable improvements in public health." Elaine Rodgers, Health DevelopmentTable of ContentsIntroduction; Theories and concepts of partnerships; Public health partnerships: What’s the prognosis?; The view from the bridge: Senior practitioners’ views on public health partnerships; The view from the frontline: Frontline practitioners’ views on public health partnerships; The changing policy context: New dawn or poisoned chalice?; Conclusion: The future for public health partnerships.

    £75.99

  • Governance Commissioning and Public Health

    Bristol University Press Governance Commissioning and Public Health

    Book SynopsisBy exploring the impact of different dimensions of governance on decision-making, this book argues that governance and population health are inextricably linked. Relevant to students, practitioners, policy-makers and anyone interested in governance and decision-making for public health.Trade Review"This book is an excellent guide to understanding the complexities and interconnections of governance, commissioning and public health in the context of recent public health policy in the English NHS and local government." David Evans, Professor in Health Services Research, University of the West of England"A resource for all public health graduates and practitioners who are or will be working in the public health sector." Dr Krishna Regmi, University of BedfordshireTable of ContentsIntroduction; Dimensions of governance; Commissioning for health and wellbeing; Levers for change (1): governance arrangements; Levers for change (2): incentives; Prioritising public health investment; Public involvement in commissioning; Conclusions.

    £28.49

  • Governance Commissioning and Public Health

    Bristol University Press Governance Commissioning and Public Health

    Book SynopsisBy exploring the impact of different dimensions of governance on decision-making, this book argues that governance and population health are inextricably linked. Relevant to students, practitioners, policy-makers and anyone interested in governance and decision-making for public health.Trade Review"This book is an excellent guide to understanding the complexities and interconnections of governance, commissioning and public health in the context of recent public health policy in the English NHS and local government." David Evans, Professor in Health Services Research, University of the West of England"A resource for all public health graduates and practitioners who are or will be working in the public health sector." Dr Krishna Regmi, University of BedfordshireTable of ContentsIntroduction; Dimensions of governance; Commissioning for health and wellbeing; Levers for change (1): governance arrangements; Levers for change (2): incentives; Prioritising public health investment; Public involvement in commissioning; Conclusions.

    £75.99

  • PeopleCentred Public Health

    Bristol University Press PeopleCentred Public Health

    Book SynopsisPeople-centred public health provides a comprehensive and accessible overview of policy, practice and research in how members of the public can be involved in delivering health improvement as volunteers or lay health workers, drawing on a major study of lay engagement in public health, and using case studies and real life examples.Trade Review"Acknowledging citizens are part of the solution, not the problem, could lead to a 21st century flourishing of Public Health as important as the first one in the 19th century." Trevor Hopkins, Asset Based Consulting & co-author of 'A glass half-full'“Participation is essential to health promotion action and people have to be at the centre of decision-making processes for it to be effective. This book offers a valuable, critical and timely analysis as government policy develops on active citizenship.” Jane Wills, Professor of Health Promotion, London South Bank University"I recommend this book to anyone interested in the future of public health. It offers a compelling guide to the policies, research and practice for anyone that is engaged in helping people and communities to become active citizens taking control of the factors that will radically improve their health." David Buck, Senior Fellow, Public health and health inequalities, Kings FundTable of ContentsForeword ~ Professor Sir Michael Marmot and Dr Mike Grady; Preface ~ Dr Stephen Peckham and Professor David Hunter; Introduction; The policy context; Lay health workers in practice; Benefits and value; The lay perspective; Walking for Health: a case study; Sexual health outreach: a case study; Community Health Educators: a case study; Citizen involvement in neighbourhood health: a case study; Commissioning and delivery; Dispelling the myths; Future directions.

    £28.49

  • PeopleCentred Public Health

    Bristol University Press PeopleCentred Public Health

    Book SynopsisPeople-centred public health provides a comprehensive and accessible overview of policy, practice and research in how members of the public can be involved in delivering health improvement as volunteers or lay health workers, drawing on a major study of lay engagement in public health, and using case studies and real life examples.Trade Review"Acknowledging citizens are part of the solution, not the problem, could lead to a 21st century flourishing of Public Health as important as the first one in the 19th century." Trevor Hopkins, Asset Based Consulting & co-author of 'A glass half-full'“Participation is essential to health promotion action and people have to be at the centre of decision-making processes for it to be effective. This book offers a valuable, critical and timely analysis as government policy develops on active citizenship.” Jane Wills, Professor of Health Promotion, London South Bank University"I recommend this book to anyone interested in the future of public health. It offers a compelling guide to the policies, research and practice for anyone engaged in helping people and communities to become active citizens taking control of the factors that will radically improve their health." David Buck, Senior Fellow, Public Health and Health Inequalities, Kings Fund"A clear and lively presentation of the issues from the perspectives of paid staff and lay health workers...a good introduction to key theoretical and practical issues about lay involvement in health promotion." Sociology of Health and Illness"This book provokes thinking and discussion on how to help deliver effective public health initiatives in the community. It is relevant for people working in public health who wish to develop knowledge on how to influence future practice." Hannah Marriage, Leicestershire Partnership Trust, Nursing Times.netTable of ContentsForeword ~ Professor Sir Michael Marmot and Dr Mike Grady; Series editors' preface; Introduction; The policy context; Lay health workers in practice; Benefits and value; The lay perspective; Walking for Health: a case study; Sexual health outreach: a case study; Community Health Educators: a case study; Citizen involvement in neighbourhood health: a case study; Commissioning and delivery; Dispelling the myths; Future directions.

    £75.99

  • Reforming Healthcare

    Bristol University Press Reforming Healthcare

    Book SynopsisReforming healthcare: What's the evidence? is the first major critical overview of the research published on healthcare reform in England from 1990 onwards by a team of leading UK health policy academics.Table of ContentsIntroduction; The NHS in 1990; Reorganising the NHS, 1990–2010; 'Central control' reorganisation in the NHS in the 2000s; Local dynamic reform in the NHS since 2000; The prospects for NHS reorganisation post-2010; Conclusion.

    £27.54

  • Reforming Healthcare

    Bristol University Press Reforming Healthcare

    Book SynopsisReforming healthcare: What's the evidence? is the first major critical overview of the research published on healthcare reform in England from 1990 onwards by a team of leading UK health policy academics.Table of ContentsIntroduction; The NHS in 1990; Reorganising the NHS, 1990–2010; 'Central control' reorganisation in the NHS in the 2000s; Local dynamic reform in the NHS since 2000; The prospects for NHS reorganisation post-2010; Conclusion.

    £77.39

  • Health Divides

    Bristol University Press Health Divides

    Book SynopsisClare Bambra examines the social, environmental, economic and political causes of health inequalities, how they have evolved over time and what they are like today. Revealing gaps in life expectancy of up to 25 years between places just a few miles apart, this important book demonstrates that where you live can kill you.Trade Review“This clearly written book, full of striking examples from around the world, shows that geography is as relevant for population health as ever” Professor Johan Mackenbach, Erasmus Medical Center, Netherlands"This numerical journey through the geographies of health and disease drives home one vital message: inequalities of place create inequalities in health. As the book eloquently observes, the political economy and geography of inequality largely determines how well, and how long, one is likely to live." Professor Ronald Labonte, University of Ottawa, Canada"Bambra’s razor sharp, timely and comprehensive analysis should be read by anyone concerned about inequality." Mary O'Hara, Guardian Journalist and author“Drawing on current and historical data from the UK and the US, Clare Bambra brilliantly demonstrates how increasing geographical and social health inequities stem from policy decisions and how different political choices could reduce them” Professor Louise Potvin, Canada Research Chair, University of Montreal, Canada & Fellow of the Canadian Academy of Health Sciences“A highly accessible text that provides a forensic investigation into how and why geography matters for health and inequalities.…Profoundly important and complemented with urgent and thought- provoking guidelines for what needs to be done to address this seemingly intractable societal problem.” Professor Jamie Pearce, University of Edinburgh, Scotland and Co-Editor, Health and Place"An excellent overview of the importance of geography for public health. A strong contribution to the health geography and public health literatures which highlights the importance of politics and policies for the unequal spatial distribution of health. I recommend it.” Dr Paul Norman, University of Leeds, England and Co-Editor, Population, Space and Place“Clare Bambra, a global leader in population health research who has been at the avant-garde in understanding how politics matters for life and death, has contributed a major, readable new statement that captures crucial insights from a new wave of political epidemiology. Health Divides will change the way you think about health and illness”. Professor Jason Beckfield, Harvard University, USA"A broad-ranging account of how place is implicated in large and growing health inequalities in some of the most affluent societies of the world. …squarely implicates policies of the neoliberal era in a compelling argument that, if heeded, could make for a healthier society" Professor James R. Dunn, McMaster University, Canada and Co-Editor, Journal of Epidemiology and Community Health“I recommend this book strongly to health professionals and medical students as it provides a comprehensive overview of health inequalities and the multiple connections between where we live and how long we live” Professor Pali Hungin, President of the British Medical Association"A welcome supplemental text for courses in health policy and introductory epidemiology, as well as a valuable primer for policy-makers." Science"Clare Bambra provides a good, easy-to-understand introduction to the major causes of health inequality in rich countries." Socialist Party"Inequality in the UK is nothing to do with the poor being a hopeless underclass, destined for extinction in a Darwinian world where only the fittest survive. As Clare Bambra... spells out, it has everything to do with factors such as poor housing, poor nutrition and lack of educational and employment opportunities." Times Higher Education"[The book's] messages should be loudly broadcast and be compulsory reading for politicians." Doctors for the NHS Newsletter"A careful analysis of persistent geographical health inequalities." - Health Affairs“an important book that demonstrates the value of careful analysis of health inequities data and close examination of the factors that explain why the data show the patterns they do.” International Journal of Epidemiology"getAbstract recommends Bambra’s report to forwardthinking leaders and public health advocates." - getAbstract, Vietnam News“Bambra also ends the book with a rallying note to her readers: we need income redistribution, devolution of power and a resourcing of the regions to make economic growth work for all.” People, Place and PolicyTable of ContentsForeword ~ Danny Dorling; Health Divides; From King Cholera to the C Word; In Sickness and In Health; Placing Life and Death; It’s the (Political) Economy; Too Little, Too Late; Past, Present, Future.

    £13.99

  • Religion and Health Care in East Africa

    Bristol University Press Religion and Health Care in East Africa

    Book SynopsisThis book is the first to investigate what role religion plays in health care in East Africa. Taking in to account the geopolitical and economic environments of the region, the authors examine the roles played by individual and group beliefs, government policies, and pressure from the Millennium Development Goals in affecting health outcomes.Trade Review"This book will fascinate scholars, practitioners, policy makers, and erudite readers alike. The authors leverage an impressive array of original evidence to present a persuasive argument about the relationship between spiritual and physical practices. This matters, and it makes for compelling reading." Ron E. Hassner, University of California, BerkeleyTable of ContentsPreface Religion, health care, and Africa Background knowledge, theorizing, and evidence Uganda Mozambique Ethiopia What have we learned? Conclusion

    £77.39

  • The NHS at 75

    Bristol University Press The NHS at 75

    Book SynopsisIn its 75th anniversary year, this book examines the history, evolution and future of the NHS. With contributions from leading researchers and experts across a range of fields, it provides a long-term critical review of the NHS and key themes in health policy.Table of ContentsForeword by Simon Stevens 1. The NHS at 75: An Unfolding Story – Mark Exworthy, Russell Mannion and Martin Powell 2. NHS Governance: The Centre Claims Authority – Scott Greer 3. Health and Care Funding at 75 – Anita Charlesworth, Nihar Shembavnekar and George Stevenson 4. The Devolved Nations – John Stewart 5. NHS at 75: General Practice Through the Lens of Access – Kath Checkland, Jennifer Voorhees, Jonathan Hammond and Sharon Spooner 6. NHS Hospitals and the Bedpan Doctrine: The First 75 Years – Rod Sheaff and Pauline Allen 7. Quality and the NHS: Fair-Weather Friends or a Long-Standing Relationship? – Ross Millar, Justin Waring and Mirza Lalani 8. Improving Health and Tackling Health Inequalities: What Role for the NHS? – Martin Powell and Mark Exworthy 9. NHS Managers at a Crossroads: Part of the Problem or the Solution? – Ian Kirkpatrick 10. Forgotten, Neglected and a Poor Relation? Reflecting on the 75th Anniversary of Adult Social Care – Catherine Needham and Jon Glasby 11. The NHS at 75 in Comparative Perspective – Ian Greener 12. Our NHS? The Changing Involvement of Patients and the Public in England’s Health and Care System – Ellen Stewart, Amit Desai and Giulia Zoccatelli 13. After 75 Years, Whither the NHS? Some Conclusions – Martin Powell, Mark Exworthy and Russell Mannion

    £72.00

  • 21st Century Global Mental Health

    John Wiley & Sons 21st Century Global Mental Health

    1 in stock

    Book Synopsis

    1 in stock

    £112.50

  • HACCP A Practical Approach Author S Mortimore

    Springer-Verlag New York Inc. HACCP A Practical Approach Author S Mortimore

    1 in stock

    Book SynopsisForeword.- Acknowledgements.- About the Authors.- Disclaimer.- About this Book.- Prologue.- 1. An Introduction to HACCP and its role in food safety control.- 2. Preparation and planning to achieve effective food safety management.- 3. Hazards, their significance and control.- 4. Prerequisites for food safety PRPs and Operational PRPs.- 5. Designing food safety.- 6. How to do a HACCP Study.- 7. Implementation, Verification and Maintenance for Ongoing Risk Management.- 8. Considerations for HACCP application in different supply chain sectors.- Epilogue.- References, further reading and resource materials.- Appendices.- Index.Trade ReviewMortimore and Wallace point out that since they last updated the book there have continued to be many failures in the food supply chain. Some of these are world renowned, many were significant national failures, and many, many more were small, isolated, and sometimes tragic events occurring in local communities all around the world. So what has gone wrong? Is HACCP not working? Sadly, the answer to this question is that it hasn’t had a chance to work. Far from being “done,” HACCP has been poorly implemented and under-utilized in probably the majority of food companies. Twenty years ago developments in HACCP were fairly major, and some governments saw its implementation as a remedy for all of their country’s food safety issues. In reality, use of the HACCP approach does offer a practical and major contribution to the way forward, but only if the people charged with its implementation have the proper knowledge and expertise to apply it effectively. Whilst a new book isn’t by itself going to solve that problem, the authors hope that it may help some companies to do better.- Land O'Lakes, Inc., Arden Hills, MNTable of ContentsForeword.- Acknowledgements.- About the Authors.- Disclaimer.- About this Book.- Prologue.- 1. An Introduction to HACCP and its role in food safety control.- 2. Preparation and planning to achieve effective food safety management.- 3. Hazards, their significance and control.- 4. Prerequisites for food safety – PRPs and Operational PRPs.- 5. Designing food safety.- 6. How to do a HACCP Study.- 7. Implementation, Verification and Maintenance for Ongoing Risk Management.- 8. Considerations for HACCP application in different supply chain sectors.- Epilogue.- References, further reading and resource materials.- Appendices.- Index.

    1 in stock

    £71.99

  • Microbial Pathogenesis Infection and Immunity

    Springer-Verlag New York Inc. Microbial Pathogenesis Infection and Immunity

    15 in stock

    Book SynopsisThe Complement System as a Viral Target for Immune Evasion.- Modulation of Type I Interferon Response by RNA Viruses.- Viroporins: Differential Functions at Late Stages of Viral Life Cycles.- Mycobacterium tuberculosis: Innate Immune Recognition and Persistence.- Candida and Candidiasis.- Mechanisms of Pathogenesis of Aspergillosis.- Airway Epithelium Interactions with Aspergillus fumigatus.- Anti-Fungal Innate and Adaptive Immune Responses.- Host-pathogen interaction in Malaria and Trypa nosomiasis.- The Host Pathogen Interaction and Immunomodulation During Leishmaniasis.- Immune responses induced by parasitic worms.- Pathogenic Persistence and Evasion mechanisms in Schistosomiasis.- Transmissible Spongiform Encephalopathies: Passage from Gut to Brain.Table of Contents1. The Complement System as a Viral Ta rgetfor Immune Evasion................................................................................1Ajitanuj Rattan, Rewati Kasbe, Jayati Mullick and Arvind SahuAbstract......................................................................................................................................... 1Introduction.................................................................................................................................. 1Role of Complement in Combating Viruses............................................................................... 2Complement Evasion by Viruses: Diverse Strategies................................................................ 6Conclusion.................................................................................................................................. 172. Modulation of Type I Interferon Responseby RNA Viruses..........................................................................................28Suchita BhattacharyyaAbstract....................................................................................................................................... 28Introduction................................................................................................................................ 28RNA Viruses............................................................................................................................... 29Type I Interferon System............................................................................................................ 31Modulation of Type I Interferon Response by RNA Viruses.................................................. 31Conclusion.................................................................................................................................. 333. Viroporins: Differential Functions at Late Stagesof Viral Life Cycles.............................................................................38Francois Kien, Huailiang Ma, Stefan Díaz Gaisenband and Béatrice NalAbstract....................................................................................................................................... 38Introduction................................................................................................................................ 38Molecular Organizations and Ion Channel Activities of IAV M2,SARS‑CoV E, HCV p7 and HIV‑ 1 Vpu Viroporins......................................................... 42Differential Roles of Viroporins during Virus Morphogenesis and Release.......................... 46Conclusion.................................................................................................................................. 53xviii Contents4. Mycobacterium tuberculosis:Innate Immune Recognitionand Persistence......................................................................................63Mycobacterium tuberculosis:Innate Immune Recognitionand Persistence......................................................................................63Munirah Abdul‑Aziz and Anthony G. TsolakiAbstract....................................................................................................................................... 63Introduction................................................................................................................................ 63Initial Stages of M. tuberculosis Infection................................................................................. 64Macrophage Involvement and M. tuberculosis Persistence..................................................... 69Granuloma Formation and M. tuberculosis Persistence......................................................... 70Conclusion.................................................................................................................................. 73M. tuberculosis Infection................................................................................. 64Macrophage Involvement and M. tuberculosis Persistence..................................................... 69Granuloma Formation and M. tuberculosis Persistence......................................................... 70Conclusion.................................................................................................................................. 73M. tuberculosis Persistence..................................................... 69Granuloma Formation and M. tuberculosis Persistence......................................................... 70Conclusion.................................................................................................................................. 73M. tuberculosis Persistence......................................................... 70Conclusion.................................................................................................................................. 735. Candida and Candidiasis............................................................................82Candida and Candidiasis............................................................................82Thomas HöfkenAbstract....................................................................................................................................... 82Introduction................................................................................................................................ 82Medically Important Candida Species...................................................................................... 83Pathogenicity Mechanisms......................................................................................................... 83Experimental Systems to Study Candidiasis............................................................................ 84Adherence................................................................................................................................... 85Invasion....................................................................................................................................... 86Secreted Hydrolytic Enzymes.................................................................................................... 87Polymorphism............................................................................................................................ 88Candida Species...................................................................................... 83Pathogenicity Mechanisms......................................................................................................... 83Experimental Systems to Study Candidiasis............................................................................ 84Adherence................................................................................................................................... 85Invasion....................................................................................................................................... 86Secreted Hydrolytic Enzymes.................................................................................................... 87Polymorphism............................................................................................................................ 88Biofilm Formation...................................................................................................................... 92Interaction with Bacteria........................................................................................................... 95Phenotypic Switching and Mating............................................................................................. 96Metabolic Flexibility and Nutrition Acquisition...................................................................... 96Stress Adaptation....................................................................................................................... 97Host Responses........................................................................................................................... 98Antifungal Drugs and Drug Resistance.................................................................................... 99Conclusion................................................................................................................................ 100...................................................................................................................... 92Interaction with Bacteria........................................................................................................... 95Phenotypic Switching and Mating............................................................................................. 96Metabolic Flexibility and Nutrition Acquisition...................................................................... 96Stress Adaptation....................................................................................................................... 97Host Responses........................................................................................................................... 98Antifungal Drugs and Drug Resistance.................................................................................... 99Conclusion................................................................................................................................ 1006. Mechanisms of Pathogenesisof Aspergillosis...................................................................................115Savneet Kaur, Kavita Kale, Taruna Madan and P. Usha SarmaAbstract..................................................................................................................................... 115Introduction.............................................................................................................................. 115Invasive Pulmonary Aspergillosis (IPA)................................................................................. 116Allergic Bronchopulmonary Aspergillosis (ABPA)................................................................ 127Conclusion................................................................................................................................ 132Contents xix7. Airway Epithelium Interactionswith ASPERGILLUS fumigatus.........................................................138ASPERGILLUS fumigatus.........................................................138Neelkamal ChaudharyAbstract..................................................................................................................................... 138Introduction.............................................................................................................................. 138Airway Epithelium Interaction with A. fumigatus................................................................. 139Toll‑Like Receptors................................................................................................................... 140Non‑TLR Receptors.................................................................................................................. 142Other Antimicrobial Mechanisms........................................................................................... 143Conclusion................................................................................................................................ 144A. fumigatus................................................................. 139Toll‑Like Receptors................................................................................................................... 140Non‑TLR Receptors.................................................................................................................. 142Other Antimicrobial Mechanisms........................................................................................... 143Conclusion................................................................................................................................ 1448. Anti‑Fungal Innate and Adaptive Immune Responses.............149Uday Kishore, Suhair M. Abozaid and Mohammed N. Al‑AhdalAbstract..................................................................................................................................... 149Introduction.............................................................................................................................. 150Innate Immune Mediated Defense against Fungi.................................................................. 151Adaptive Immunity and Fungal Pathogens............................................................................ 156Conclusion................................................................................................................................ 1599. Host‑pa thogen interaction in Malariaand Trypa nosomiasis.........................................................................167Janez Ferluga, Annapurna Nayak, and Uday KishoreAbstract..................................................................................................................................... 167Introduction: Malaria, Background and Life Cycle of the Parasite.................................... 168Malaria Immunity and Chronicity Development.................................................................. 170Complement Involvement........................................................................................................ 174PfEMP1: Virulence and Pathogenesis Modulation................................................................ 175Cerebral Malaria...................................................................................................................... 176Placental Malaria...................................................................................................................... 177EMP1: Virulence and Pathogenesis Modulation................................................................ 175EMP1: Virulence and Pathogenesis Modulation................................................................ 175Cerebral Malaria...................................................................................................................... 176Placental Malaria...................................................................................................................... 177P. falciparum Anaemia.............................................................................................................. 178A Role of Red Cell Blood Groups in Malaria Virulence Modulaton.................................... 179Merozoite Erythrocyte Invasion.............................................................................................. 179Human African Trypanosomiasis (HAT)................................................................................ 180Parasite Life Cycle.................................................................................................................... 181HAT Pathogenesis.................................................................................................................... 182Evasion of Innate and Adaptive Immunity by Trypanosome............................................... 184Potential Involvement of the Complement System................................................................ 185Genetic HAT and Host Diversity and Disease Phenotypes................................................... 186American Trypanosomiasis (Chagas Disease)........................................................................ 187Anaemia.............................................................................................................. 178Anaemia.............................................................................................................. 178A Role of Red Cell Blood Groups in Malaria Virulence Modulaton.................................... 179Merozoite Erythrocyte Invasion.............................................................................................. 179Human African Trypanosomiasis (HAT)................................................................................ 180Parasite Life Cycle.................................................................................................................... 181HAT Pathogenesis.................................................................................................................... 182Evasion of Innate and Adaptive Immunity by Trypanosome............................................... 184Potential Involvement of the Complement System................................................................ 185Genetic HAT and Host Diversity and Disease Phenotypes................................................... 186American Trypanosomiasis (Chagas Disease)........................................................................ 187T. cruzi Life Cycle...................................................................................................................... 188Cell Invasion............................................................................................................................. 188Pathogenesis of Chagas Disease............................................................................................... 188Chronic Chagas Disease........................................................................................................... 189Role of Adipose Tissue.............................................................................................................. 190Cytokine Expression and Regulaton....................................................................................... 190Complement and Immune Evasion......................................................................................... 191Conclusion................................................................................................................................ 192Life Cycle...................................................................................................................... 188T. cruzi Life Cycle...................................................................................................................... 188Cell Invasion............................................................................................................................. 188Pathogenesis of Chagas Disease............................................................................................... 188Chronic Chagas Disease........................................................................................................... 189Role of Adipose Tissue.............................................................................................................. 190Cytokine Expression and Regulaton....................................................................................... 190Complement and Immune Evasion......................................................................................... 191Conclusion................................................................................................................................ 192Life Cycle...................................................................................................................... 188Life Cycle...................................................................................................................... 188Cell Invasion............................................................................................................................. 188Pathogenesis of Chagas Disease............................................................................................... 188Chronic Chagas Disease........................................................................................................... 189Role of Adipose Tissue.............................................................................................................. 190Cytokine Expression and Regulaton....................................................................................... 190Complement and Immune Evasion......................................................................................... 191Conclusion................................................................................................................................ 192xx Contents10. The Host Pathogen Interactionand Immunomodulation During Leishmaniasis...............203Surajit Bhattacharjee and Arijit BhattacharyaAbstract..................................................................................................................................... 203Introduction.............................................................................................................................. 204Initial Interaction and Phagocytosis....................................................................................... 205Macrophage Functions Altered by Leishmania...................................................................... 206Microbicidal Free Radical Production.................................................................................... 207Impairment of Antigen Presentation....................................................................................... 208Modulation of Cytokine Production........................................................................................ 209Chemokine and Chemokine Receptors in Leishmaniasis..................................................... 211Cytokine–Chemokine Networks in Leishmaniasis................................................................ 213Leishmania...................................................................... 206Microbicidal Free Radical Production.................................................................................... 207Impairment of Antigen Presentation....................................................................................... 208Modulation of Cytokine Production........................................................................................ 209Chemokine and Chemokine Receptors in Leishmaniasis..................................................... 211Cytokine–Chemokine Networks in Leishmaniasis................................................................ 213Leishmania‑Induced Alteration of Host Cell Signaling......................................................... 214Toll‑Like Receptors (TLRs)..................................................................................................... 220Immune Responses against Leishmania Infection................................................................. 221Conclusion................................................................................................................................ 223‑Induced Alteration of Host Cell Signaling......................................................... 214Leishmania‑Induced Alteration of Host Cell Signaling......................................................... 214Toll‑Like Receptors (TLRs)..................................................................................................... 220Immune Responses against Leishmania Infection................................................................. 221Conclusion................................................................................................................................ 223‑Induced Alteration of Host Cell Signaling......................................................... 214‑Induced Alteration of Host Cell Signaling......................................................... 214Toll‑Like Receptors (TLRs)..................................................................................................... 220Immune Responses against Leishmania Infection................................................................. 221Conclusion................................................................................................................................ 223Leishmania Infection................................................................. 221Conclusion................................................................................................................................ 22311. Immune responses induced by pa rasitic worms....................233Janez Ferluga, Lubna Kouser and Uday KishoreAbstract..................................................................................................................................... 233Introduction.............................................................................................................................. 234Helminth Type‑2 Immunity and Allergy................................................................................. 235Hygiene Hypothesis on Allergies Increase.............................................................................. 237Examples of Type 2 Immunity................................................................................................. 237Tissue‑Parasite Variation in Type 2 Immunity....................................................................... 238Potential Complement Involvement in Helminth and Autoimmunity................................. 240Complement Evasion................................................................................................................ 242Trichinellosis............................................................................................................................. 243Filariasis.................................................................................................................................... 244Taeniasis.................................................................................................................................... 245Schistosomiasis......................................................................................................................... 246Conclusion................................................................................................................................ 24712. Pathogenic Persistence and Evasion mechanismsin Schistosomiasis...............................................................................255Annapurna Nayak and Uday KishoreAbstract..................................................................................................................................... 255Introduction.............................................................................................................................. 256Life Cycle into Intermediate and Vector Host........................................................................ 257Skin Penetration by Cercariae: Breaking the First Line of Defense.................................... 259Modulation of the Host’s Immune Response.......................................................................... 260Granulomas in Acute and Chronic Schistosomiasis.............................................................. 263Contribution of Various Immune Cells in the Immunopathology....................................... 265Complement Evasion by Schistosome Paramyosin............................................................... 265Immune Modulation of the Snail............................................................................................. 267Conclusion................................................................................................................................ 270Contents xxi13. TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES—Passage from Gut to Brain............................................................276Daniel A. MitchellAbstract..................................................................................................................................... 276Introduction.............................................................................................................................. 277The Replication of Infectious Prions....................................................................................... 277The Importance of the Gut in TSEs........................................................................................ 278Prion Proliferation in Lymphoid Tissues................................................................................ 279The Role of Dendritic Cells in Prion Trafficking................................................................... 279The Role of the Complement System in Prion Disease.......................................................... 280Prion Passage to the Brain and Neurocytoxicity.................................................................... 281Conclusion................................................................................................................................ 282................................................................... 279The Role of the Complement System in Prion Disease.......................................................... 280Prion Passage to the Brain and Neurocytoxicity.................................................................... 281Conclusion................................................................................................................................ 282

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