Pharmacology Books

6014 products


  • Pharmaceutical Press An Introduction to Clinical Pharmaceutics

    Out of stock

    Book SynopsisConsiders the importance of pharmaceutics and pharmaceutical dosage form design by considering the clinical use of modern drugs. This book also considers the use and behaviour of dosage forms in different age groups and patient groups along with developments such as personalised therapies and genomics.Table of Contents1. Introduction; 2. Drugs and Excipients; 3. Oral Formulations; 4. Parenteral Formulations; 5. Adverse Reactions; 6. Pharmaceutics and the Neonate; 7. Pharmaceutics of Disease States; 8. Advanced Delivery Systems.

    Out of stock

    £999.99

  • Drugs and the Liver

    Pharmaceutical Press Drugs and the Liver

    Out of stock

    Book SynopsisEnables the practitioner to assess liver function using biochemical markers, other tests, signs, symptoms and disease knowledge. This practical guide covers background information on liver function, the principles of drug use in liver disease and includes a section of worked examples of commonly asked questions.Trade Review'For those pharmacists involved in medication reviews, interpretation of liver function test results is an essential part of the process. This book provides an excellent explanation of each parameter and the limitations of using the results alone when assessing the degree of liver function.'Jackie Smith, a pharmaceutical advisor, Chemist and Druggist, October 2008 -- Jackie Smith * Chemist and Druggist *'This book combines all pertinent issues relating to liver dysfunction and medication use in one reference. The authors and contributors have done an excellent job to make the book a practical tool that can be used by clinicians when making therapeutic choices rather than merely presenting pharmacokinetic principles and expected alterations in liver disease.'Sharya Vaughan Bourdet, PharmD BCPS, The Annals of Pharmacotherapy Vol. 42, July/August 2008 -- Sharya Vaughan Bourdet * The Annals of Pharmacotherapy *'The book is written primarily for pharmacist clinicians, but it serves as a useful review for anyone who has an interest in drug metabolism and liver function...the thorough but easy to understand review of the liver anatomy and function is a highlight. This is a good read for those who need to brush up on these topics.'Patrick J. McDonnell, Temple University School of Pharmacy. Doody Enterprises, Inc. April 2008 -- Patrick J. McDonnell * Doody Enterprises *Table of ContentsPart 1 - Understanding Liver Function; 1. Introduction to the Anatomy of the Liver; 2. Functions of the Liver; 3. Causes of Liver Disease and Dysfunction; 4. Assessing Liver Function; Part 2 - Principles of Drug Use in Liver Disease; 5. Pharmacokinetics of Drugs in Liver Disease; 6. Undesirable Side Effects; Part 3 - Putting the Theory into Practice; 7. Applying the Principles - introduction; 8. Introducing the Aide Memoire; 9. Scenario 1 Choice of Analgesia; 10. Scenario 2 Choice of Anti-emetic; 11. Scenario 3 Choice of Anti-hyperlipidaemic Agent; 12. Scenario 4 Choice of Hormone Replacement Therapy (HRT); 13. Scenario 5 Choice of Contraceptive; Appendix 1 - Detailed Description of the Patient Cases; Appendix 2 - The Blank Aide Memoire Form.

    Out of stock

    £999.99

  • Pharmaceutical Press Introduction to Statistics in Pharmaceutical

    Out of stock

    Book SynopsisA self-contained introduction to Statistics, presented in the context of clinical trials and pharmaceutical drug development. This title focuses on the statistical analyses most commonly used in drug development. It emphasises the importance of descriptive statistics as well as inferential statistics.Trade Review'It fills the gap that exists between books that focus on research design and those that address statistical methods. The authors have clearly met this worthy objective. This book fills a unique position and uses innovative method.'Michael R Jacobs, BS, PharmD (Temple University of Pharmacy) Doody Enterprises July 2008 -- Michael R Jacobs * Doody's Notes *Table of ContentsSection 1 Setting the Scene; Statistic, Statistics and Statistical Analyses; New Drug Development; Section 2 Design, Analysis and Interpretation; Data, Central Tendency and Variation; Research Questions and Research Hypotheses; Study Design and Methodology; Hypothesis Testing and Estimation; Section 3 Pre-clinical Drug Development; Overview of Pre-clinical Drug Development; Pharmacokinetic Studies; Pharmacodynamic Studies; Section 4 Clinical Drug Development; Phase 1: Clinical Trials; Confirmatory Clinical Trials: Safety Data; Confirmatory Clinical Trials: Efficacy Data; Health Outcomes Data; Section 5 Additional Pharmaceutical Statistical Techniques; Analysis of Frequencies; Analysis of Association and Prediction; Analysis of Ranked Outcomes; Section 6 Writing Regulatory Documents and Scientific Manuscripts; Scientific Communication: Goals and Necessary Statistical Skills.

    Out of stock

    £999.99

  • Pharmacy Case Studies

    Pharmaceutical Press Pharmacy Case Studies

    5 in stock

    Book SynopsisHelps students to take an integral approach to pharmacy via a series of pharmacy cases. This book tests knowledge gained within the individual areas of law and ethics, pharmaceutics, pharmacology and pathology by examples, bringing together various areas taught on the degree course.Table of ContentsGastrointestinal; Cardiovascular; Respiratory; CNS; Infections; Endocrine; Obstetrics, Gynaecology and UTI; Malignant Disease; Nutrition and the Blood; Musculoskeletal and Joint; Eyes; ENT; Skin; Immunological / Vaccines; Liver Disease; Renal Disease; Paediatrics; Elderly.

    5 in stock

    £31.35

  • Foundation in Pharmacy Practice

    Pharmaceutical Press Foundation in Pharmacy Practice

    Book SynopsisGives an introductory overview to pharmacy practice. This book is suitable for first year undergraduate students, providing a starting point for further study and is facilitated by regular signposting and referencing to specific texts. It also includes an easily navigated glossary of reference terms.Trade Review'This book is detailed enough to provide readers with a strong background in pharmacy practice and to serve as a useful reference for seasoned professionals. It is comprehensive guide to practice.'Richard P Berardi, RPh, BSc, MHA (Temple University Hospital) Doody Enterprises Sept 2008 -- Richard P Berardi * Doody's Notes *Table of ContentsWhat is Pharmacy Practice?; Structure and function of the NHS in England; An overview of community pharmacy - The role of the community pharmacist; past, present and future; An overview of hospital pharmacy; An overview of industrial sector pharmacy; Introduction to Medicines Management; An overview of the structure and function of the Royal Pharmaceutical Society of Great Britain; Essential Communication Skills for Pharmacists; Prescription types and legal requirements; Prescription interpretation and understanding; Packaging of medicines; Labelling of medicines; Extemporaneous dispensing: a beginner's guide; Compliance, adherence and concordance; Sale and supply of medicines: Risk and advice provision; Major Routes of Drug Administration; Glossary of common Pharmacy Practice terms.

    £31.35

  • Pharmaceutical Press Nonmedical Prescribing

    Out of stock

    Book SynopsisPresents an overview of non-medical prescribing by health professions other than doctors and covers the ethics, legal and patient safety framework. This book includes background information on history, competencies needed (includes RPSGB guidelines) and the moral aspects of prescribing.Table of Contents1. Development of Non-medical Prescribing; 2. Legal, Ethical and Moral Aspects of Prescribing; 3. Clinical Governance and Patient Safety on Prescribing; 4. Principles of Prescribing and Drug Handling; 5. Clinical Decision Making and Evidence Based Prescribing; 6. Prescribing in Diabetes; 7. Prescribing in Palliative Care; 8. Prescribing in Cardiology; 9. Respiratory Disease Management; 10. Prescribing in Oncology; 11. Prescribing in Mental Health.

    Out of stock

    £999.99

  • Pharmaceutical Press FASTtrack Therapeutics

    Out of stock

    Book SynopsisA guide for students providing bullet points of basic information on therapeutics. It focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and important self-assessment section which includes MCQs, case studies, sample essay questions and worked examples.Table of Contents1. Cardiovascular system; 2. Respiratory system; 3. Gastro-intestinal Tract; 4. Renal System; 5. Infectious Diseases; 6. Central nervous system; 7. Endocrine system; 8. The Skin; 9. The Eye; 10. Musculoskeletal Disorders.

    Out of stock

    £999.99

  • Injectable Drugs Guide

    Pharmaceutical Press Injectable Drugs Guide

    Book SynopsisA guide to the important information for safe and effective administration of injectable drugs. It includes information on: final concentration of reconstituted solutions; stability; periodicity of monitoring; and, unusual electrolyte, glucose and excipients content.Trade Review"...the book is a quick guide to the use, admixture, administration, monitoring, storage, physical characteristics, and other clinical information for injectable medications. The tables are well organized and the information is easy to retrieve and follow...This is a quick and dirty, go-to book for information on the use of injectable medications. It is a handy, "just in case" reference (just in case you don't know how to mix or administer, or are unsure of the compatibility of a medication). This is a good reference."Judith Klevan, BA biology, BS Pharmacy (Jeanes Hospital), Doody's Notes, May 2011 -- Judith Klevan * Doody's Notes *

    £48.60

  • Sampsons Textbook of Radiopharmacy

    Pharmaceutical Press Sampsons Textbook of Radiopharmacy

    Book SynopsisThe fourth edition of this well-established text has been completely revised and updated to reflect developments in the science and practice of radiopharmacy that have taken place over the last ten years.Trade Review"All the chapters describe the real basics of the subject, therefore the book is very suitable as textbook and reference work for students on radiopharmacy or persons working in the field of nuclear medicine...the book is well referenced, so that the reader wishful to deepen any topic, may find a bunch of useful information at the end of each chapter; moreover, beside the obvious target represented by radiopharmacists/radiochemists, we would recommend the book to all the other professionals involved in the field of Nuclear Medicine". Sergio Todde, University of Milano-Bicocca, Philip Elsinga, LIMCG Groningen, European Journal of Nuclear Medicine and Molecular Imaging (EJNMMI) 2011 -- Sergio Todde * European Journal of Nuclear Medicine and Molecular Imaging *"...the 4th edition is a very useful book. We are using it in our MSc Radiopharmacy option. lt is more detailed and more up to date than Saha's textbook (our other prescribed book)...The book is well indexed...We will continue to use the book for the course." Dr Beverley Summers, Department of Pharmacy/ Photobiology Laboratory, Medunsa Campus (UL), South Africa, June 2011. -- Dr Beverley SummersTable of Contents1. What Is Radiopharmacy? 2. Nuclear Structure and Radioactivity 3. Radiation Protection 4. Detection of Radiation 5. Physics Applied to Radiopharmacy - Imaging Instruments for Nuclear Medicine 6. Production of Radionuclides 7. Radiopharmaceutical Chemistry - Basic Concepts 8. Fundamentals of Technetium and Rhenium Chemistry 9. Trivalent metals and thallium 10. Radiohalogenation 11. Radiolabeling Approaches with Fluorine-18 12. Carbon-11 13. Other Radioelements 14. Radiolabelling of Biomolecules 15. Radiopharmacokinetics 16. Receptors and Transporters 17. Radiation Dosimetry for Targeted Radionuclide Therapy 18. Survey of Current Diagnostic Radiopharmaceuticals 19. Survey of Current Therapeutic Radiopharmaceuticals 20. Formulation of Radiopharmaceuticals 21. Principles and Operation of Radionuclide Generators 22. Quality Assurance Requirements 23. Quality Control Methods for Radiopharmaceuticals 24. Radiolabelling of Blood Cells - Theory and Practice 25. Particulate Radiopharmaceuticals 26. Design and Operation of Radiopharmacy Facilities 27. Regulation of Radiopharmacy Practice in Europe 28. Regulation of Radiopharmacy Practice in the United Kingdom 29. Regulation of Nuclear Pharmacy Practice in the United States 30. Packaging and Transport of Radiopharmaceuticals 31. Patient Safety and Dispensing of Radiopharmaceuticals 32. The Effect of Patient Medication 33. Use of Drugs to Enhance Nuclear Medicine Studies 34. Molecular Biology Techniques in Radiopharmaceutical Development 35. Chemical Characterisation of Radiopharmaceuticals 36. Evaluation of Radiopharmaceuticals Using Cell Culture Models 37. Animal Models: Preclinical Molecular Imaging, Why and How?

    £72.90

  • Pharmaceutical Press Good Pharmacovigilance Practice Guide

    Out of stock

    Book SynopsisPharmacovigilance is the science of collecting, monitoring, researching, assessing and evaluating information from healthcare providers and patients on the adverse effects of medications, biological products, herbalism and traditional medicines. This text provides practical advice about achieving an appropriate system of pharmacovigilance.Trade Review'This is an easy-to-read, practical guide that navigates relevant pharmacovigilance legislation and guidance. It is a valuable single reference for an array of information.'Joshua J Gagne PharmD MS, The Annals of Pharmacotherapy, Volume 43, May 2009 -- Joshua J Gagne * The Annals of Pharmacotherapy *'This book provides valuable insight to the agency's (MHRA) expectations. Those whose primary role lies outside the area of pharmacovigilance are very likely to benefit from the book because it should help them to better understand the commitments the organization is making to maximise product safety.'Michael R Jacobs, BS PharmD, Doody's Notes, 27th February 2009 -- Michael R Jacobs * Doody's Notes *Table of Contents1. EEA Qualified Person Responsible for Pharmacovigilance; 2. Management of Pharmacovigilance Data; 3. Spontaneous Case Processing; 4. Literature Searching; 5. Periodic Safety Update Reports; 6. Evaluation of Safety Data; 7. Risk Management Plans; 8. Reference Safety Information; 9. Quality Management System; 10. Interactions Between Pharmacovigilance and Other Functions; 11. Contracts and Agreements; 12. Safety Reporting for Clinical Trials.

    Out of stock

    £999.99

  • MCQs in Pharmacy Practice

    Pharmaceutical Press MCQs in Pharmacy Practice

    Out of stock

    Book SynopsisCovers topics featured in pharmacy undergraduate registration and licensing multiple choice examinations. This book covers common general pharmacy practice interventions and operations and other topics commonly featured in examinations such as simple pharmaceutical calculations, doses, strengths, nomenclature, abbreviations and dosage forms.Trade Review'A great review for pharmacists, pharmacy students, and for use in an intern program. This latest edition is divided into both "open book" and "closed book" sections and contains a total of 800 multiple choice questions designed to assess participants knowledge, analytical skills, and the ability to apply this knowledge base in clinical practice.'The International Journal of Pharmaceutical Compounding, Volume 6, Issue 40, 2nd October 2009 * International Journal of Pharmaceutical Compounding *Table of Contents600 examination type MCQs.; The book is divided into an open book and a closed book section; Each section comprises three tests of 100 questions.; he questions are practice-oriented and are intended to assess students' knowledge, their evaluative and analytical skills, and their ability to apply knowledge base in clinical practice.

    Out of stock

    £999.99

  • Pharmaceutical Press Developing Your Prescribing Skills

    Out of stock

    Book SynopsisDeveloping Your Prescribing Skillshelps practitioners and all new prescribers to assess their current skills, and recognise their skills gaps. It identifies ways to meet learning needs and be accountable for prescribing, both as individuals and teams.Trade Review"This book uses real-life case scenarios to describe the art of prescribing for those new to the field...The reflective questions are a great way to think about the scenario and its clinical aspects...This book offers an excellent approach to learning. The use of real-life scenarios is always a useful tool for educating new practitioners. This is what makes this book unique"Zina T. Saidi, Pharm.D. (Jeanes Hospital), Doody's Notes, March 2011. -- Zina T. Saidi * Doody's Notes *

    Out of stock

    £999.99

  • MCQs in Pharmaceutical Science and Technology

    Pharmaceutical Press MCQs in Pharmaceutical Science and Technology

    Book SynopsisMCQs in Pharmaceutical Science and Technology includes 600 MCQs progressing from basic science through to clinical considerations.

    £31.35

  • Pharmaceutical Press FASTtrack Pharmaceutical Compounding and

    Out of stock

    Book SynopsisA student guide to the key dosage forms encountered in extemporaneous pharmaceutical compounding and dispensing.Trade Review"Of value to new practitioners involved in compounding nonsterile pharmaceutical preparations...Each chapter starts with an overview of the dosage form followed by discussions of general methods, a number of worked examples, and then a self-assessment section...each chapter includes both key points and tips. The detail included in the examples in the chapters on dosage forms is exceptional...it delivers a practical guide for students whose curricula continue to provide didactic and practice experiences in compounding." Joseph Boullata, PharmD (University of Pennsylvania College of Nursing), Doody's Notes, July 2012 -- Joseph Boullata * Doody's Notes *Table of Contents1. Introduction; 2. Solutions; 3. Suspensions; 4. Emulsions; 5. Creams; 6. Ointments, Pastes and Gels; 7. Suppositories and Pessaries; 8. Powders and Capsules; Bibilography; Further Reading; Appendix 1: Glossary of Terms Used in Formulations; Appendix 2: Abbreviations Commonly Used Within Pharmacy; Appendix 3: Formulae Contents

    Out of stock

    £999.99

  • Pharmaceutical Press FASTtrack Applied Pharmaceutical Practice

    Out of stock

    Book SynopsisGuides the student pharmacist or pharmacy technician through the main stages involved in pharmaceutical dispensing. This reference text accompanies the compulsory dispensing courses found in all undergraduate MPharm programmes and equivalent technical training courses.Trade Review"Applied Pharmaceutical Practice is good for all years and all stages of the MPharm course whether you are a first year learning from scratch or just refreshing your addled fourth year memory. It's great for practical dispensing, OSCEs, law exams or for anyone working in a pharmacy as a student, technician or newly qualified pharmacist...a brilliantly written book, student friendly, as well as being clear and interesting enough to read from cover to cover" Katrina Fredericks, BPSA pharmacy student, 2013 -- Katrina FredericksTable of Contents1. Introduction, medicines classification and standard operating procedures 2. NHS supply in the community 1: prescription forms and prescribing 3. NHS supply in the community 2: prescribers and the dispensing process 4. NHS supply within hospitals 5. Non-NHS supply 6. Controlled drugs 7. Emergency supply 8. Patient counselling and communication 1: the basics of patient communication 9. Patient counselling and communication 2: product-specific counselling points 10. Poisons and spirits Appendix 1: Commonly encountered qualifications of healthcare professionals Appendix 2: Abbreviations commonly used within pharmacy

    Out of stock

    £999.99

  • Pharmaceutical Press FASTtrack Pharmacology

    Out of stock

    Book SynopsisProvides a brief account of drug action, as a study or revision aid. The authors have taken a therapeutic area and considered the major classes of drugs, their actions and, to a limited degree, their uses.Trade Review"This book is intended to enhance material covered in traditional pharmacology textbooks...Visuals, algorithms, diagrams, and key points interspersed throughout the book help reinforce and summarize the material. Readers will be able to assess their understanding of the material through self-assessment questions at the conclusion of each chapter...Undergraduate pharmacy students, as well as other healthcare students, will find this a useful guide to help prepare for examinations." Neela A. Bhajandas, PharmD, Doody's Notes, May 2013. -- Neela A. Bhajandas * Doody's Notes *"The book provides good basic knowledge of pharmacology and is well organized, with sections on principles, followed by sections on the drugs used to treat different therapeutic areas...Overall the authors have generally obtained a good balance of core information that is accessible, without it being a textbook in disguise!...Whilst this book is aimed primarily at Pharmacists, I am sure it would also be of value as a revision aid for Medical students...my own daughter who is a 4th year Medical student said she would buy it, an endorsement indeed!" Professor Clive Page, British Journal of Pharmacology, June 2012 -- Professor Clive Page * British Journal of Pharmacology *Table of Contents1. Pharmacodynamics 2. Receptors 3. G-proteins and Their Downstream Signaling Cascades 4. Ion Channels and Transporters 5. Quantitive Pharmacology 6. Autonomic Pharmacology 7. Local Mediators 8. Pharmacokinetics and Drug Metabolism 9. Gastric Pharmacology 10. Lower Gastrointestinal Pharmacology 11. Antiemetics 12. Antiarrhythmics 13. Cardiovascular Drugs 14. Renal and Urinary Pharmacology 15. Antithrombotic Agents 16. Antiobesity Drugs 17. Asthma and Chronic Obstructive Pulmonary Disease 18. Allergy 19. Anxiolytics and Hypnotics 20. Antidepressants 21. Antiepileptic Drugs 22. Antipsychotic Drugs 23. Parkinson's Disease 24. Analgesics 25. Drugs of Abuse 26. General Anaesthetics 27. Neuromuscular Blocking Drugs 28. Thyroid Disorders 29. Diabetes Mellitus 30. Antibacterial Agents 31. Non-bacterial Infections 32. Anticancer Drugs 33. Steroids 34. Oral Contraceptives 35. Immunopharmacology 36. Biopharmaceuticals 37. Variation in Clinical Efficacy

    Out of stock

    £999.99

  • Pharmaceutical Press FASTtrack Pharmaceutics Drug Delivery and

    Out of stock

    Book SynopsisThis FASTtrack book systematically reviews important concepts and facts relating to the delivery and targeting of drugs. Relevant examples of delivery systems are given throughout the book with a focus on delivery systems that have actually reached clinical reality.Trade Review"I believe this book is truly a hidden gem... The self-assessment MCQ’s help to solidify knowledge covered in their relevant section, as well as highlighting areas of difficulty which could be easily found within the book and revised again if needed. I found that these questions were of similar difficulty to the MCQ’s used in lectures and past exam papers, facilitating exam prep...The diagrams were all very clear, simple and easy to understand, even when explaining complex mechanisms and routes of targeting...In conclusion I found this book really useful for basic and advanced understanding and revision of such a daunting unit. In addition to this it has also helped with thesis writing for my final year project that has a drug-targeting underlining."Lauren Jones, 4th year student, Portsmouth University, February 2014. -- Lauren JonesTable of Contents1. Controlling Drug Delivery; 2. Immediate Release Drug Delivery Systems I; 3. Immediate Release Drug Delivery Systems II; 4. Delayed Release Drug Delivery Systems; 5. Sustained Release Delivery Systems; 6. Controlled-release Dosage Forms; 7. Site Directed Drug Targeting; 8. Carriers for Drug Targeting

    Out of stock

    £999.99

  • FASTtrack Pharmaceutics  Dosage Form and Design

    Pharmaceutical Press FASTtrack Pharmaceutics Dosage Form and Design

    Out of stock

    Book SynopsisThis revision guide for students delivers the essentials of dosage formulation in a concise and easy-to-use format.Table of Contents1. Pharmaceutical solutions for administration to the gastrointestinal tract; 2. Pharmaceutical disperse systems 1: suspensions - general principles and the formulation of suspensions for oral administration; 3. Pharmaceutical disperse systems 2: emulsions and creams; 4. Pharmaceutical disperse systems 3: ointments, pastes, lotions, gels and related formulations; 5. Parenteral formulations; 6. Ocular, nasal and otic dosage forms; 7. Vaginal and rectal dosage forms; 8. Respiratory dosage forms; 9. Solid-dosage forms 1: tablets; 10. Solid-dosage forms 2: capsules; 11. Introduction to pharmaceutical engineering

    Out of stock

    £999.99

  • Pharmaceutical Press FASTtrack Chemistry of Drugs

    Out of stock

    Book SynopsisA revision guide on pharmaceutical and medicinal chemistry. The book covers all aspects of the chemistry of drugs and includes key points, tips, and self-assessment questions to aid in learning.Trade Review"4 stars. This book is a brilliant resource written by two experts in the field of pharmaceutical and medicinal chemistry. It is intended to complement lecture notes and prepare pharmacy undergraduates for their exams. It would also be a useful resource for practising pharmacists, researchers, scientists and all those with an interest in chemical structure and bonding, intermolecular interactions, drug licensing and pharmacopoeia. The text is well written, with a clear, consistent and open layout. There are overviews outlining what the reader should know after completing each section. The text is presented in concise bullet points, with key points, tips and simple diagrams." Oliver McGurk, medical science undergraduate, Nursing Standard 29(9) October 2014 -- Oliver McGurk * Nursing Standard *Table of Contents1. Chemical structure and bonding; 2. Intermolecular interactions; 3. Acids and bases; 4. Stereochemistry; 5. Chemical reaction mechanisms; 6. Chemistry of electrophiles and nucleophiles; 7. Chemistry of aromatic compounds; 8. Chemistry of carbonyl compounds; 9. Chemistry of aromatic heterocyclic compounds; 10. Amino acids, peptides and proteins; 11. Carbohydrates and nucleic acids; 12. Lipids and steroids; 13. Chemical stability of drugs; 14. Drug metabolism; 15. Molecular spectroscopy and pharmaceutical analysis; 16. Drug licensing and pharmacopoeia; Answers to self-assessment

    Out of stock

    £999.99

  • Drugs in Use Case studies for pharmacists and

    Pharmaceutical Press Drugs in Use Case studies for pharmacists and

    Book SynopsisDrugs in Use: Case Studies for Pharmacists and Prescribers helps you to bridge the gap between theoretical knowledge about medicines and the practical application to your patients. With an ever increasing shift of focus from theory to practice this book promotes evidence-based medicine and illustrates how you can optimise drug therapy in response to the needs of your individual patients. It will prove a valuable resource to pharmacists and prescribers. The cases have been updated to reflect recent changes in medicines use and this new edition boasts: New evidence concerning optimal care; Additional coverage of situations with difficulties in treatment optimisation; Significant focus on major advances in therapeutics; Self study questions and answers within each case. With self study questions and answers to accompany each case, you will find this a useful resource throughout your career. As a student, it will assist your studies and as a practicing pharmacist or prescriber in hospitalTrade Review"Drugs In Use" focuses on clinical skills, and that is a very useful area for modern pharmacists, both in hospital as well as community... When I was scanning through the book, I got 'stuck' easily by the instructive and fascinating case descriptions...I was learning new things, and this probably is the strength of the book. It helps to translate abstract knowledge into applicable clinical expertise... A good read for pharmacists who are interested in pharmacotherapy." J.W.F. van Mil, International Journal of Clinical Pharmacy, 36(469), 2014. -- J.W.F. van Mil * International Journal of Clinical Pharmacy *"Pharmacy students can benefit from practicing their skills and formulating their own opinion...pharmacists can maintain clinical competencies by resolving these scenarios...written by pharmacists with considerable experience...5 stars!" Melissa M. Ranieri, BS, PharmD(Temple University School of Pharmacy), Doody's Notes, 2013. -- Melissa M. Ranieri * Doody's Notes *"This book provides evidence-based medicine and illustrates how one can optimize drug therapy in response to the needs of individual patients...This is a very interesting and applicable book for pharmacy practice today." Compounding Today, 10(27) 5 July 2013. * Compounding Today *Table of ContentsHypertension; Ischaemic Heart Disease; Myocardial Infarction; Cardiac Failure; Stroke; Type I Diabetes in Childhood; Type II Diabetes Mellitus; Acute Renal Failure; Chronic Renal Failure Managed By Automated Peritoneal Dialysis; Renal Transplantation; Asthma; Chronic Obstructive Pulmonary Disease; Peptic Ulcer; Crohn's Disease; Alcoholic Liver Disease; Rheumatoid Arthritis; Osteoporosis; Epilepsy; Parkinson's Disease; Depression; Schizophrenia; Dementia; Substance Misuse; Human Immunodeficiency (HIV) Disease: Opportunistic Infections and Antiretroviral Therapy; Oncology; Symptom Control in Palliative Care; Eczema; Psoriasis; Anticoagulant Therapy; Colorectal Surgery; Cholecystectomy; Medicines Management; Managing Medicine Risk.

    £40.85

  • Prescribing Medicines for Children

    Pharmaceutical Press Prescribing Medicines for Children

    Book SynopsisPrescribing for children is a particularly challenging discipline due to specific issues of drug absorption, metabolism, distribution and excretion. The aim of this book is to improve understanding in all aspects of paediatric prescribing, from the development of suitable drugs through to their practical administration.

    £54.00

  • Pharmaceutical Press Disease Management

    Out of stock

    Book SynopsisDisease Management is a comprehensive introduction to the management of diseases which are commonly encountered in primary care.Trade ReviewA useful book for students and preregistration trainees... Common diseases — such as diabetes, hypertension, asthma, depression and peptic ulceration — are described, followed by brief summaries of the pharmacology of the drugs used to manage these conditions. There is a strong focus on drug choice so that the reader can appreciate the rationale behind logical prescribing.... ...drug interactions represent an important therapeutic challenge and attempts have been made to highlight important examples and how they may be overcome. The book will be of greatest value to pharmacy students in the latter part of their courses and to preregistration graduates undertaking their clinical practice. Laurence A. Goldberg, The Pharmaceutical Journal, 12 October 2016 -- Laurence A. Goldberg * The Pharmaceutical Journal *Table of ContentsPart A The patient 1 Signs and symptoms 2 Clinical laboratory tests 3 Lifestyle 4 Herbal medicine and alternative remedies Part B Treatment 5 Drug Choice and prescribing 6 Adverse drug reactions and interactions 7 Clinical pharmacokinetics Part C Gastrointestinal diseases 8 Dyspepsia and peptic ulcer disease 9 Nausea and vomiting 10 Lower gastrointestinal problems 11 The liver patient Part D Cardiovascular diseases 12 Hypertension 13 Lipids and cardiovascular risk 14 Obesity 15 Ischaemic heart disease 16 Heart failure 17 Thromboembolic prophylaxis 18 Anaemias 19 The renal patient Part E Respiratory diseases 20 Coughs and colds 21 Allergy 22 Respiratory diseases: asthma and chronic obstructive pulmonary disease Part F Central nervous system disorders 23 Migraine 24 Epilepsy 25 Affective disorders 26 Anxiety disorders 27 Insomnia 28 Schizophrenia 29 Parkinson's disease Part G Pain 30 Pain management 31 Musculoskeletal pain Part H Cancer 32 The cancer patient and chemotherapy 33 The cancer patient and palliative care; Part I Infections 34 Bacterial infections 35 Non-bacterial infections Part J Dermatology 36 Dermatology Part K Endocrine disorders 37 Diabetes mellitus 38 Thyroid disorders; Feedback on self-assessments Appendices 1 Formulary of some important classes of drugs, commonly used examples, mechanisms of action and uses 2 Some important clinical measurements and therapeutic drug monitoring.

    Out of stock

    £999.99

  • Pharmacy Registration Assessment Questions

    Pharmaceutical Press Pharmacy Registration Assessment Questions

    Book SynopsisPharmacy Registration Assessment Questions is developed around the current GPhC registration exam. Comprising of 400 questions, the book covers all sections such as BO5, EMQ, Classification, and Calculations, which will allow students to practice questions in the new format before the examinations. All questions are based on BNF72.Table of ContentsPrefaceAcknowledgementsAbout the authorsAbbreviationsChanges to the assessmentHow to use this bookBest of five questionsSection ASection BSection CSection DExtended matching questionsSection ASection BSection CSection DCalculation questionsSection ASection BSection CSection DAnswersBest of five answersExtended matching answersCalculation answersIndex

    £31.35

  • Pharmacy Registration Assessment Questions 2

    Pharmaceutical Press Pharmacy Registration Assessment Questions 2

    Book SynopsisPharmacy Registration Assessment Questions 2 features more than 400 entirely new, closed book and calculation questions in line with current GPhC guidance. This revision aid gives you the opportunity to practice a variety of question styles found in the assessment including single best answer questions, extended matching questions and calculations.Table of ContentsContents Preface Acknowledgements About the authors Abbreviations How to use this book Best of five questions Section A Section B Section C Section D Extended matching questions Section A Section B Section C Section D Calculation questions Section A Section B Section C Section D Best of five answers Extended matching answers Calculation answers Index

    £33.25

  • Pharmacy Registration Assessment Questions 3

    Pharmaceutical Press Pharmacy Registration Assessment Questions 3

    Out of stock

    Book SynopsisPharmacy Registration Assessment Questions 3 features more than 400 entirely new, closed book and calculation questions in line with current GPhC guidance. This revision aid gives you the opportunity to practice a variety of question styles found in the assessment including single best answer questions, extended matching questions and calculations.Table of Contents Contents Preface Acknowledgements About the authors Abbreviations How to use this book Best of five questions Section A Section B Section C Section D Extended matching questions Section A Section B Section C Section D Calculation questions Section A Section B Section C Section D Best of five answers Extended matching answers Calculation answers Index

    Out of stock

    £33.25

  • Pharmacy Foundation Assessment Questions 1

    Pharmaceutical Press Pharmacy Foundation Assessment Questions 1

    Out of stock

    Book SynopsisPharmacy Foundation Assessment Questions 1 features over 400 revision questions and it is fully aligned to the latest guidance regarding the assessment process from the GPhC. Questions are based on latest editions of both the BNF an BNFC, alongside the most current treatment guidelines available at the time of writing. This book also includes questions featuring prescriptions, patient information and pictures of conditions, replicating the type of questions students may encounter in the real exam. Written by a team of experienced authors who all work with foundation trainee pharmacists every day and including questions that are practical and will truly challenge students.

    Out of stock

    £33.25

  • Herbally Yours A Comprehensive Herbal Handbook

    Sound Nutrition,U.S. Herbally Yours A Comprehensive Herbal Handbook

    1 in stock

    Book Synopsis

    1 in stock

    £10.99

  • Pharmacology Mind Maps for Medical Students and

    Taylor & Francis Ltd Pharmacology Mind Maps for Medical Students and

    1 in stock

    Book SynopsisPharmacology Mind Maps is meant as a concise companion for the pharmacology students, enabling them to revise the subject in a short time through the innovative and effective technique of mind maps, after understanding the subject from a standard reference textbook. This handy manual provides the subject information in a condensed form, helping in last minute revision. Mind mapping is slowly taking over traditional methods and techniques and is explored extensively for a subject like pharmacology which is both an essential as well as a difficult subject to master for a medical student. This book will thus help the students to read, revise and recollect the subject easily and rapidly.Table of ContentsGENERAL PHARMACOLOGY. Definitions, drug nomenclature, and sources of drugs. Routes of drug administration. Pharmacokinetics and applied aspects. Pharmacodynamics. Adverse drug reactions. New drug approval process and clinical trials. AUTONOMIC NERVOUS SYSEM (ANS) PHARMACOLOGY. Introduction to ANS. Cholinergic system and drugs. Anticholinergics. Skeletal muscle relaxants. Adrenergic system and drugs. CARDIOVASCULAR PHARMACOLOGY. Antihypertensives. Calcium channel blockers, drug treatment of angina pectoris, and myocardial infarction. Cardiac glycosides and treatment of cardiac failure. Antiarrhythmics. Diuretics and antidiuretics. Pharmacotherapy of shock. CENTRAL NERVOUS SYSEM (CNS) PHARMACOLOGY. Introduction to CNS and alcohol. Sedative hypnotics. Antiepileptics. Antidepressants. Mood stabilizers and lithium. Antipsychotics. Drug treatment of Parkinsonism and Alzheimer’s disease. General anesthetics (GA). Local anesthetics (LA). Opioid analgesics. CNS stimulants/drugs of abuse. AUTACOID PHARMACOLOGY. Autacoids, histamine and antihistaminics. 5-Hydroxytryptamine agonists and antagonists and drug treatment of migraine. Eicosanoids and leukotrienes. Nonsteroidal anti-inflammatory drugs (NSAIDs). Drugs used in rheumtoid arthritis and gout VI. RESPIRAORY PHARMACOLOGY. Drugs used in the treatment of bronchial asthma and chronic obstuctive pulmonary disorders (COPD). Drugs used in the treatment of cough. HEMATOLOGICAL PHARMACOLOGY. Hematinics. Hemostatic agents. Anticoagulants. Antiplatelet agents. Thrombolytics (fibrinolytics) and antifibrinolytics. Hypolipidemic drugs. GASTROINTESINAL PHARMACOLOGY. Drug therapy of peptic ulcer and GERD. Emetics and antiemetics. Drug treatment of constipation, treatment of IBS, and IBD. Drug treatment of diarrhea. ENDOCRINE PHARMACOLOGY. Hypothalamic and pituitary hormones. Thyroid hormones and antithyroid agents. Estrogen, progestins, and hormonal contraceptives. Androgens and anabolic steroids. Corticosteroids. Insulin and oral antidiabetic agents. Agents affecting calcium balance. Drugs acting on uterus. CHEMOTHERAPY. General chemotherapy. Beta-lactam antibiotics. Sulfonamides. Chemotherapy of urinary tract infections and sexually transmitted diseases. Quinolones. Macrolides. Broad-spectrum antibiotics – Tetracyclines and chloramphenicol. Aminoglycosides. Miscellaneous antibiotics. Chemotherapy of tuberculosis (TB). Chemotherapy of leprosy. Chemotherapy of malaria. Drugs for amebiasis / pneumocystosis / leishmaniasis / trypanosomiasis. Antiviral drugs. Antifungal drugs. Anthelmintics. Antiseptics and disinfectants. Cancer chemotherapy. MISCELLANEOUS. Chelating agents. Immunosuppressants and immunostimulants Index

    1 in stock

    £34.99

  • Copper Amine Oxidases

    Taylor & Francis Inc Copper Amine Oxidases

    1 in stock

    Book SynopsisAlthough the amount of research on copper amine oxidases has grown rapidly and substantially in the past decade, the field unfortunately suffers from lack of cohesion and significant confusion surrounds aspects as simple as confirmation of enzyme identities. This book describes the structure of the enzymes, the role of copper, and of the unusual cofactor 6-hydroxydopa quinine derived from a posttranslational modification of a tyrosine residue. It also covers the differences of between AOs from bacteria, plants, and mammals. Finally, the text examines the importance of this ubiquitous class of enzymes in physiology and in metabolism of biogenic amines.Table of ContentsHistory. Nomenclature and Potential Functions of Copper Amine Oxidases. Cofactors of Amine Oxidases: Copper Ion and Its Substitution and the 2, 4, 5-Trihydroxylphenylalanine Quinone. Copper Amine Oxidases from Plants. Soluble Copper Amine Oxidases from Mammals. Membrane-Bound Copper Amine Oxidases. Copper Amine Oxidase Genes. Mechanism of TPQ Biogenesis in Prokaryotic Copper Amine Oxidase. Copper Amine Oxidase Crystal Structures. Plasma Amine Oxidases in Various Clinical Conditions and in Apoptosis. Copper Amine Oxidases in Intestine Diseases. Copper Amine Oxidases in Adipose Tissue-Related Disorders. Copper Amine Oxidases in Adhesion Molecules in Renal Pathology and in Alzheimer’s Disease and VAP-1 in Leukocyte Migration. Inhibitors of Copper Amine Oxidases: Past, Present, and Future. Pharmacological Applications of Copper Amine Oxidases. Copper Amine Oxidases as Antioxidant and Cardioprotective Agents. Biotechnological Aspects of Copper Amine Oxidases. Concluding Remarks. References.

    1 in stock

    £180.50

  • Chiroptical Spectroscopy

    Taylor & Francis Inc Chiroptical Spectroscopy

    1 in stock

    Book SynopsisThis book details chiroptical spectroscopic methods: electronic circular dichroism (ECD), optical rotatory dispersion (ORD), vibrational circular dichroism (VCD), and vibrational Raman optical activity (VROA). For each technique, the text presents experimental methods for measurements and theoretical methods for analyzing the experimental data. It also includes a set of experiments that can be adopted for undergraduate teaching laboratories. Each chapter is written in an easy-to-follow format for novice readers, with necessary theoretical formalism in appendices for advanced readers. Table of ContentsPolarized Light; Chiral Molecules; Interaction of Circularly Polarized Light with Chiral Molecules; Quantum Chemical Formulation of Chiroptical Spectroscopy; Prediction of Chiroptical Spectra; Conformational Analysis; Experimental Methods for Measuring Chiroptical Spectra; Comparison of Experimental and Calculated Spectra; Chiral Aggregation, Equilibria and the Horeau effect; Applications of Chiroptical Spectra

    1 in stock

    £175.75

  • Pharmacology

    Elsevier Health Sciences Pharmacology

    15 in stock

    Book SynopsisIntroduces you to basic pharmacology principles, with an emphasis on applying them to the kinds of clinical situations you will encounter on the job. This title helps you learn about how different drugs work in the body, drug dosage calculation methods, drug administration routes and procedures, and more.Trade ReviewThe second edition of Pharmacology: Principles and Applications is a thorough, comprehensive pharmacology text that is well suited for health professions students as a result of its extensive content and effective use of review questions, exercises, color, icons, and graphics to engage students for optimal learning. The text is divided in such a manner that health professions faculty can easily determine which sections of the text should be emphasized in a specific discipline. Journal of Pharmacy Technology - November/December 2008Table of ContentsSection 1: General Aspects of Pharmacology 1. Legal and Ethical Aspects of Pharmacology 2. Basics of Pharmacology 3. Drug Information and Drug Forms 4. Understanding Drug Dosages for Special Populations 5. Reading and Interpreting Medication Labels and Orders and Documenting Appropriately Section 2: Mathematics for Pharmacology and Dosage Calculations 6. Math Review 7. Measurement Systems and Their Equivalents 8. Converting Between Measurement Systems 9. Calculating Doses of Nonparenteral Medications 10. Calculating Doses of Parenteral Medications Section 3: Medication Administration 11. Safety and Quality Assurance 12. Enteral Routes 13. Percutaneous Routes 14. Parenteral Routes Section 4: Pharmacology for Multisystem Application 15. Analgesics and Antipyretics 16. Immunizations and the Immune System 17. Anitmicrobials, Antifungals, and Antivirals 18. Antineoplastic Agents 19. Nutritional Supplements and Alternative Medicines Section 5: Medication Related to Body Systems 20. Endocrine System Disorders 21. Eye and Ear Disorders 22. Drugs for Skin Conditions 23. Musculoskeletal System Disorders 24. Gastrointestinal System Disorders 25. Respiratory System Disorders 26. Circulatory System and Blood Disorders 27. Urinary System Disorders 28. Reproductive System Disorders 29. Neurological System Disorders 30. Drugs for Mental Health and Behavioral Disorders 31. Drugs of Abuse and Misuse Appendices A. Check Your Understanding Answers B. Drug-Nutrient and Drug-Drug Interactions Glossary

    15 in stock

    £70.29

  • Dermatokinetics of Therapeutic Agents

    Taylor & Francis Inc Dermatokinetics of Therapeutic Agents

    1 in stock

    Book SynopsisNovel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity. The skin, one of our key defensive barriers, allows certain topically applied substances and toxins to pass. The dermatokinetics of a drug determines the efficacy of treatment of skin disorders.Presenting the first comprehensive reference on this important area of research, Dermatokinetics of Therapeutic Agents includes a general overview of the theoretical as well as practical aspects of dermatokinetics and addresses the impact of a drug delivery system on the dermatokinetics of drugs. Chapters and illustrations cover introductory aspects and the significance, methods, and models used in dermatokinetic studies of therapeutic agents.Topics include: Theoretical Models for Dermatokinetics of Therapeutic Agents Drug Delivery Approaches to Modulate Dermatokinetics of DrugsTable of ContentsIntroduction to Dermatokinetics. Theoretical Models for Dermatokinetics of Therapeutic Agents. Drug Delivery Approaches to Modulate Dermatokinetics of Drugs. Conventional Methods of Cutaneous Drug Sampling. Cutaneous Microdialysis. Sampling Substrates by Skin Permeablization. Spectroscopic Techniques in Dermatokinetics Studies. Dermatokinetics of Gene Therapeutics. Regulatory Perspective of Dermatokinetic Studies.

    1 in stock

    £185.25

  • Chemistry of Natural Products

    Taylor & Francis Inc Chemistry of Natural Products

    1 in stock

    Book SynopsisThe second edition of a bestseller, this book discusses the common structural and stereochemical features of naturally occurring organic compounds. It includes a variety of examples to illustrate varied aspects so that the range of structure and behavior exhibited by these compounds is retained within the set framework. The author explores the increasing application of physical (spectroscopic) methods like IR, NMR, CD, ORD, MS, and High Resolution Mass Spectroscopy without undermining the importance of classical chemical methods. The section on problem solving helps to develop an analytical and critical evaluation of the data. Table of ContentsIntroduction. Structure. Stereochemistry. Reactions and Rearrangements. Synthesis. Biosynthesis. Biological Significance of Secondary Metabolites. Problems. Index.

    1 in stock

    £118.75

  • Taylor & Francis Inc Carbohydrate Chemistry

    Out of stock

    Book SynopsisThe second volume in the series Carbohydrate Chemistry: Proven Synthetic Methods, Volume 2 offers a collection of synthetic procedures valuable to the practice of synthetic carbohydrate chemistry. The series takes an important and unique approach in that all described procedures have been independently verified as reliable and reproducible. With editors and contributors who are highly respected scientists in the field, this book provides a widely useful reference for both researchers and students, exploring carbohydrate chemistry from both academic and industrial points of view.The book begins with an introductory section that offers tricks and tips collected by the series editor from many years of experience working in carbohydrate laboratories. The subsequent chapters present detailed protocols on both specific synthetic transformations and the preparation of common synthetic intermediates, with figures to aid in comprehension. Procedures are described for regioseleTrade Review'The contributors are the best scientists in the field and the series editor is highly respected. The volumes will ... be of use to undergraduates involved in carbohydrate workshops.'– Alexei Demchenko, Associate Professor of Chemistry and Biochemistry, Director of Graduate Studies, University of Missouri – St. Louis.‘This essential book series, focused on carbohydrate synthesis, starts with a dedication to Nobel Laureate Sir John W. Cornforth, who is credited with the first public criticism of what he pictured as ‘pouring a large volume of unpurified sewage into the chemical literature.’1 Unfortunately, this issue is not limited to the field of chemistry as many high profile cases of irreproducible experiments have led to alarms being set off even in the popular press.2 This series then serves as the much-needed water treatment plants – places where the reader can be guaranteed a good clean reproducible experiment. … at least now chemists with or without expertise in carbohydrates can count on finding reliable procedures to make sugar-based compounds at one scale – a major achievement. Not only should current practitioners gain back time lost in attempts to properly reconstruct experimental procedures, but these procedures should also allow more creative scientists to contribute to this growing area. Cornforth JW. Austr. J. Chem. 1993;46:157e70. For example, see Unreliable research: trouble at the lab. Econ. October 19, 2013.’ – Nicola L.B. Pohl, Indiana University, Department of Chemistry, Bloomington, IN, USA, for Carbohydrate Research, http://dx.doi.org/10.1016/j.carres.2015.04.007.Table of ContentsSection I: Synthetic Methods. Highly Stereoselective 1,2-cis-Glycosylations Employing C-2 (S)-(Phenylthiomethyl)benzyl Ether as a Chiral Auxiliary. Regioselective Reductive Openings of 4,6-O-Benzylidene-Type Acetals Using LiAlH4-AlCl3. A Facile Method for Oxidation of Primary Alcohols to Carboxylic Acids in Carbohydrate Synthesis. Ultrasonic Energy Promoted Allylation to Generate 1-C-(2,3,4,6-Tetra-O-benzyl-α-d-glucopyranosyl)prop-2-ene. Synthesis of a Multivalent Glycocyclopeptide Using Oxime Ligation. Reductive Amination Methodology for Synthesis of Primary Amines from Unprotected Synthons. General Preparation of Imidazole-1-sulfonate Esters. Regioselective Monoacylation and Monoalkylation of Carbohydrates Catalyzed by a Diarylborinic Ester. The Synthesis of Carbamates from Alkenylamines. Hydrolysis of Thioglycosides Using Anhydrous N-Iodosuccinimide (NIS) and Trifluoroacetic Acid (TFA). Highly Diastereoselective Construction of l-Heptosides by a Sequential Grignard Addition/Fleming-Tamao Oxidation. Synthesis of Fluorinated Exo-glycals Mediated by Selectfluor. A Direct and Stereospecific Approach to the Synthesis of α-Glycosyl Thiols. Efficient Microwave-Assisted Synthesis of 1′,2,3,3′,4,4′,6-Hepta-O-benzyl-sucrose and 1′,2,3,3′,4,4′-Hexa-O-benzylsucrose. Section II: Synthetic Intermediates. Oligosaccharide-Salicylaldehyde Derivatives as Precursors of Water-Soluble, Biocompatible Anion Receptors. Allyl 3,4,6-Tri-O-Benzyl-α-d-Mannopyranoside. Synthesis of a Spacer-Armed 6′-Sialyl-N-Acetyllactosamine. Synthesis of β-(1→3)-mannobiose. Phenyl 4,6-O-Benzylidene-1-thio-α-d-mannopyranoside. Synthesis of 1,3,4,6-Tetra-O-acetyl-α-d-glucopyranose Revisited. Synthesis of 4,6-O-Benzylidene Acetals of Methyl α-d-Glucopyranoside, Ethyl 1-Thio-β-d-gluco- and Galactopyranoside. Synthesis of α-N-Acetylneuraminic Acid Methyl Glycoside. Synthesis of Ammonium 3-Deoxy-d-manno-oct-2-ulopyranosylonate (Ammonium Kdo). Synthesis and Characterization of Tetra-O-propargyl Pentaerythritol. Improved Synthesis of Ethyl (2,3,4,6-Tetra-O-acetyl-β-d-galactopyranosyl)-(1→3)-4,6-O-benzylidene-2-deoxy-1-thio-2-trichloroacetamido-β-d-glucopyranoside. Synthesis of α-d-Galactofuranosyl Phosphate. Synthesis of 1,2 4,5-Di-O-(3,3-pentylidene)arabitol via Kinetic Acetal Formation. 1,2-Anhydro-3,4,6-tri-O-benzyl-β-d-mannopyranose. Synthesis of Glucosyl C-1 Dihalides from Tetra-O-acetyl-β-d-glucopyranosyl Chloride. Synthesis of 3,4,6-Tri-O-acetyl-d-galactal. Efficient Synthesis of Hepta-O-acetyl-β-lactosyl Azide via Phase Transfer Catalysis. Synthesis of 2,3,4,6-Tetra-O-acetyl-α-d-mannopyranosyl Azide. Synthesis of Phenyl 2,3,4,6-Tetra-O-acetyl-1-thio-β-d-galactopyranoside. An Alternative, Large-Scale Synthesis of 1,2 5,6-Di-O-isopropylidene-α-d-ribo-hex-3-ulofuranose.

    Out of stock

    £999.99

  • Clinical Pharmacology and Practical Prescribing

    Taylor & Francis Ltd Clinical Pharmacology and Practical Prescribing

    1 in stock

    Book SynopsisThe Medicine on the Move series provides fully-flexible access to subjects across the curriculum, in this case clinical pharmacology and prescribing practice, in a combination of print and mobile formats. The books are ideal for the busy medical student and junior doctor, irrespective of individual learning style and whether they are studying a subject for the first time or revisiting it during exam preparation, providing the right information whenever and wherever it is needed. Readers can choose from the book and the eBook to suit different situations, enabling them to benefit from learning medicine on the move.Print Versions of this book also include access to the ebook version.Table of ContentsCLINICAL PHARMACOLOGY. DRUGS AND PRACTICAL PRESCRIBING. SELF-ASSESSMENT.

    1 in stock

    £31.99

  • Drug Delivery

    Taylor & Francis Inc Drug Delivery

    1 in stock

    Book SynopsisIntegrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications. Examining special clinical states requiring innovative drug delivery modifications, such as hypercoagulability often seen in pregnancy, cancer, and autoimmune diseases, the book also discusses methods for improved drug delivery in clinical settings using clinical end points, clinical trials, simulations, and other venues. It also describes the latest drug delivery advances involving nanomaterTrade Review"This book is an excellent approach to the state of art in drug delivery, with the advantage of the clinical view. It is a good starting point to connect very distant spheres of knowledge in a hot spot of advanced molecular controlled release."—Guillermo R. Castro, Universidad Nacional de La Plata, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina"…unique compilation of information in the area of drug delivery, and readers will find useful information not only for their present use but also for furthering science in this area." —Ambikanandan Misra, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, IndiaTable of ContentsAn Introduction of Key Concepts in Drug Delivery. An Introduction to Pharmacokinetics: From Conventional to Advanced Systemic Drug Delivery Systems. Transporters and Enzymes Targeted Prodrugs for Improved Oral Drug Delivery. Gastroretentive Delivery: Physicochemical, Biopharmaceutical, Technological and Regulatory Considerations. Invasive vs. Non-Invasive Delivery of Insulin. Artificial Pancreas Drug Delivery. Micro/Nano Devices for Drug Delivery. Microneedle-Mediated Vaccines. Application of Nanoparticle Tracking Analysis in Drug Delivery. Microsponges for Drug Delivery. Chitosan for Advancing Drug Delivery. Gene Delivery by Electroporation. Drug Delivery Systems for Infectious Diseases. Nanotechnology in Drug Delivery to Chronic Inflammatory Diseases. Intrathecal Drug Delivery. Cancer Stem Cell Drug Delivery. Cardiac Drug Delivery. Current Developments in Nano-Therapeutics for Airway Diseases. Intravitreal Drug Delivery. Drug Delivery in Obstetrics and Gynecology. Drug Delivery Systems: A Regulatory Perspective.

    1 in stock

    £128.25

  • Heterogeneous Catalysis

    Taylor & Francis Inc Heterogeneous Catalysis

    1 in stock

    Book SynopsisFor more than a century, bioactive heterocycles have formed one of the largest areas of research in organic chemistry. They are important from a biological and industrial point of view as well as to the understanding of life processes and efforts to improve the quality of life. Heterogeneous Catalysis: A Versatile Tool for the Synthesis of Bioactive Heterocycles highlights the recent methodologies used in the synthesis of such bioactive systems and focuses on the role of heterogeneous catalysis in the design and synthesis of various biologically active heterocyclic compounds of pharmacological interest. Topics include: Synthetic protocols for the construction of heterocyclic systems employing silica-bound catalysts Recent advances in heterogeneous copper-catalyzed reactions for the synthesis of bioactive heterocycles Features of silica-based heterogeneous catalysts, such as abundance, ease of use, and stabilityTable of ContentsSynthesis of Bioactive Heterocyclic Systems Promoted by Silica-Supported Catalysts. Eco-Benign Synthesis of Indole Derivatives Employing Diverse Heterogeneous Catalysts. Solid Heterogeneous Catalysts Based on Sulfuric Acid and Transition-Metal Salts: Synthesis of Bioactive Heterocycles. Heterogeneous Copper-Catalyzed Synthesis of Bioactive Heterocycles. Silica Sulfuric Acid: A Simple and Powerful Heterogeneous Catalyst in Organic Synthesis. Application of Silica-Based Heterogeneous Catalysis for the Synthesis of Bioactive Heterocycles. Application of Organometallic Compounds as Heterogeneous Catalysts in Organic Synthesis. Ultrasound: An Efficient Tool for the Synthesis of Bioactive Heterocycles. Nano–Zinc Oxide: An Efficient Heterogeneous Catalyst for the Synthesis of Heterocyclic Compounds. Application of Heterogeneous Catalysts for the Synthesis of Bioactive Coumarins. Silver: A Versatile Heterogeneous Catalyst for Heterocyclic Synthesis. Mesoporous Materials from Novel Silica Source as Heterogeneous Catalyst.

    1 in stock

    £171.00

  • Cytochrome P450 2D6

    Taylor & Francis Inc Cytochrome P450 2D6

    1 in stock

    Book SynopsisCytochromes are proteins that catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. Cytochrome P450 2D6: Structure, Function, Regulation, and Polymorphism reviews the current knowledge of CYP2D6 as well as the maturing body of evidence indicating its significance to clinical and pharmacological researchers and practitioners.This book focuses on the critical role CYP2D6 plays in the human liver. It examines the genetic, epigenetic, physiological, pathological, and structural factors of the gene that govern the highly variable metabolism of a number of drugs in clinical use. It highlights the impact of the functional roles of CYP2D6 on clinical practice and drug development and also dTable of ContentsIntroduction to Human Cytochrome P450 Superfamily. Mammalian CYP2D Members: A Comparison of Structure, Function, and Regulation. Substrates of Human CYP2D6. Inhibitors of Human CYP2D6. Regulation of Human CYP2D6. Structure and Function of Human CYP2D6. Clinical Pharmacogenomics of Human CYP2D6. General Discussion about Human CYP2D6.

    1 in stock

    £237.50

  • Adverse Drug Interactions

    Taylor & Francis Inc Adverse Drug Interactions

    1 in stock

    Book SynopsisAdverse Drug Interactions: A Handbook for Prescribers assists clinicians by providing key information on potential adverse effects that can result from prescribing two or more drugs for simultaneous use. Interactions that are likely to give rise to life-threatening conditions, and which must therefore be completely avoided, are clearly highlighted. Less threatening but nonetheless important interactions necessitating practical measures, such as frequent monitoring and advice to patients, are also discussed.Presented in a user-friendly format, the book is organised by drug class and provides a brief summary of the mechanism underlying a particular interaction, alternative drugs lacking the same reactions that may be considered, and instructions for monitoring patients when adverse effects occur. All interactions listed in the previous edition have been reviewed and updated using the latest information available. The clinical reality of tTrade Review“There is much to commend. There are useful preliminary sections on the complexity of drug–drug interactions and the emerging role of electronic decision support systems… I was particularly pleased to see the inclusion of interactions with herbal and common over-the-counter medications, alcohol, ‘classic’ recreational drugs, vitamins and minerals, and key food groups.”—Daniel Marks, University College London Hospital, London, British Journal of Hospital MedicineTable of ContentsDrugs Acting on the Cardiovascular System. Drugs Acting on the Central Nervous System. Anticancer and Immunomodulating Drugs. Anticoagulants. Antidiabetic Drugs. Other Endocrine Drugs. Analgesics. Musculoskeletal Drugs. Anesthetic Drugs: General. Drugs to Treat Infections. Drugs Acting on the Gastrointestinal Tract. Respiratory Drugs. Metabolic Drugs. Obstetrics and Gynecology. Drugs Used to Treat the Urinary System. Drugs of Abuse. Miscellaneous. Over-the-Counter/Online Drugs, Traditional and Herbal Remedies. Appendices.

    1 in stock

    £63.64

  • Fundamentals of Asymmetric Synthesis

    Taylor & Francis Inc Fundamentals of Asymmetric Synthesis

    1 in stock

    Book SynopsisAsymmetric synthesis is an integral part of synthetic organic chemistry. Some of the reactions in this book were known prior to 1980, while several new ones, particularly catalytic asymmetric reactions, have been discovered in the recent years. The impact of this new class of reactions has been impressively extensiveboth on organic and medicinal chemistry. These reactions have been accepted whole-heartedly by synthetic organic chemists in developing shorter routes for complex natural targets as well as in the manufacture of a wide range of drug intermediates.Table of ContentsIntroduction. Terms, Definitions and Concepts in Asymmetric Synthesis. Achiral and Chiral Molecules and Their Properties. Prochirality. Enantioselective and Diastereoselective Synthesis. Methods for Monitoring Enantioselective and Diastereoselective Synthesis. Methods for Inducing Asymmetry. Chiral Substrate Controlled Asymmetric Reactions: Diastereoselection in acyclic systems. Chiral auxiliary controlled asymmetric reactions—Asymmetric α-alkylations. Chiral Stoichiometric Reagent Controlled Asymmetric Synthesis: Chiral Boron Reagents. Chiral Catalyst Mediated Asymmetric Reactions: Enzymes. Chiral Organometallic Catalysed Asymmetric Reactions: Sharpless Asymmetric Epoxidations, Dihydroxylations and Aminohydroxylations. Chiral Organometallic Catalysed Asymmetric Reactions. Organocatalysts in Asymmetric Synthesis—Chiral Additive Mediated Reactions. Asymmetric Aldol Reaction. Asymmetric Diels–Alder reactions. Stereoselective Synthesis and Stereospecific Synthesis. Index.

    1 in stock

    £175.75

  • Emerging NonClinical Biostatistics in

    Taylor & Francis Inc Emerging NonClinical Biostatistics in

    1 in stock

    Book SynopsisThe premise of Quality by Design (QbD) is that the quality of the pharmaceutical product should be based upon a thorough understanding of both the product and the manufacturing process. This state-of-the-art book provides a single source of information on emerging statistical approaches to QbD and risk-based pharmaceutical development. A comprehensive resource, it combines in-depth explanations of advanced statistical methods with real-life case studies that illustrate practical applications of these methods in QbD implementation. Table of ContentsBACKGROUND. Introduction. ANALYTICAL METHOD. Statistical Methods for Analytical Procedure Development, Validation and Transfer. Parallelism Testing of Bioassay. Validation of Assay Linearity. ROCESS DEVELOPMENT. Residual Host Cell DNA Risk Assessment. Statistical Evaluations of Viral Clearance. Pre-filtration Bio-burden Testing. Process Validation and Verification. MANUFACTURING. Specifications.

    1 in stock

    £96.99

  • Sensitive Skin Syndrome

    Taylor & Francis Inc Sensitive Skin Syndrome

    1 in stock

    Book SynopsisSensitive skin is a widely reported condition where affected individuals experience enhanced and unpleasant sensations of itching, burning and discomfort upon exposure to a wide range of environmental factors. Considerable progress in recent years has shed light on multiple aspects of this condition. This new edition sums up the advances in pathophysiology, methods of investigation, effects of environmental factors and clinical considerations in evaluation and management of affected individuals. This book provides a blend of basic science and methodologies for interested investigators as well as practical points in clinical management of patients. Table of ContentsSection I Introduction and Background 1 What is sensitive skin? Renée J.H. Richters, Natallia E. Uzunbajakava, Piet E.J. van Erp, and Peter C.M. van de Kerkhof2 Sensitive skin: a review of prevalence worldwide Charles Taieb and Laurent Misery3 Skin structure and function Golara Honari 4 The somatosensory system Francis McGlone and David ReillySection II Pathophysiology of Sensitive Skin 5 Stratum corneum and sensitive skin Enzo Berardesca6 Altered somatosensory pathways Eun Ju Kim, Dong Hun Lee, and Jin Ho Chung7 Itch and sensitive skin Martin SchmelzSection III Investigative Methods 8 Challenges of investigationLidia Maroñas-Jiménez, Elena González-Guerra, and Aurora Guerra-Tapia 9 Self-assessment of sensitive skinCharles Taieb and Laurent Misery10 Confocal Raman Micro-Spectroscopy: a new paradigm in the diagnosis of sensitive skin?Denise Falcone, Natallia E. Uzunbajakava, Piet E.J. van Erp, and Peter C.M. van de Kerkhof11 Regarding the quantification of the human skin barrier in Sensitive Skin SyndromeLuís Monteiro Rodrigues, Henrique Silva, and Catarina Rosado12 Irritant reactivity tests David A. Basketter13 Neurosensory assessment Roland JourdainSection IV Clinical Considerations 14 Sensitive skin: there is a link with ethnicity?Laurent Misery and Charles Taieb15 Gender and age influence on sensitive skinRosa Marie Andersen16 Sensitive skin: do we observe an impact on quality of life?Laurent Misery and Charles Taieb17 Perceived sensitive skin at different anatomic sites Miranda A. Farage18 Sensitive skin and non-eczematous dermatoses Ian McDonald, Helen Rea, and Martin Steinhoff19 Sensitive skin and eczematous dermatoses Arun C Inamadar and Aparna PalitSection V Environmental Factors and Everyday Products 20 Influence of air pollution on skin Sparsha Saxena and Golara Honari21 Sensitive skin, skin care products and cosmeticsEnzo Berardesca22 Fabrics and sensitive skin Gerald E. Pierard and Howard I. MaibachSection VI Management 23 Dermatotoxicology and sensitive skin syndrome Golara Honari and Howard I. Maibach 24 Formulations for sensitive skin Golara Honari and Howard I. Maibach25 Treatments for sensitive skin Martina Kerscher and Heike BuntrockIndex

    1 in stock

    £161.50

  • Kucers The Use of Antibiotics

    CRC Press Kucers The Use of Antibiotics

    1 in stock

    Book SynopsisKucers' The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference.Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internat

    1 in stock

    £475.00

  • Calpains: Pharmacology and Toxicology of a

    Taylor & Francis Inc Calpains: Pharmacology and Toxicology of a

    1 in stock

    Book SynopsisThis new edition offers a clear and through examination of the most recent results of thirty years of research on calcium-activated-neutral protease (CANP or Calpain). Coverage includes the implications of the recently gained ability to produce functionally active recombinant calpain in various human disorders such as cerebal ischemia, traumatic brain and spinal cord injury, cataract formation, myocardial infarction, and Alzheimer's disease. The resulting research to find more selective calpain inhibitors is also discussed. With a copy of Calpain: Pharmacology and Toxicology of Calcium Dependent Protease you will better understand why the calpain research area is such an exciting and promising one.Table of Contents1. The Calpain Super Family Yasuko Ono, Hiroyuki Sorimachi and Koichi Suzuki 2. Structure of Calpastian and its Inhibitory Control of Calpain Emiko Takano and Masatoshi Maki 3. The Expression of Calpain in Bacteria and in Insect Cells John Elce 4. Structure and Assembly of the Calcium-Binding Domains of Calpain Sthanam Narayana, John Elce, Debashish Chattopadhyay, Guang-da Lin, Mike Carson, Helen Blanchard, Pawel Grochulski and Miroslaw Cygler 5. Calpain Substrates, Assay Methods, Regulation, and its Inhibitory Agents Kevin Wang and Po-wai Yuen 6. Calpain In Signal Transduction John Fox and Takaomi Saido 7. The Calpain System in Muscle Tissue Ahmed Ouali and Rong-Ghi Chou 8. Involvement of Calpains in Cell Cycle G-1 - to S-Phase Progression Ronald Mellgren, Wenli Zhang, Qin Lu and Richard Lane 9. Calpain in Excitotoxicity, Cerebral Ischemia and Neuronal Apoptosis Kevin Wang, Po-wai Yuen and Kevin Lee 10. The Contribution of Calpain Proteolysis to Neuronal Death Following Traumatic Brain Injury Ronald Hayes, Andreas Kampfl and Rand Posmantur 11. The Pathophysiological Role of Calpain in Spinal Cord Injury Naren Banik, Donald Shields, Swapan Ray and Edward Hogan 12. Calpain-Mediated Proteolysis of Neuronal Structural Proteins Rodney Guttmann and Gail Johnson 13. Calpain and Cerebrovascular Injury Sung-Don Kang, Adam Arthur, Elisa Beres, Andrea Fergus, Chris Boals, Murad Bavbek and Kevin Lee 14. Calpains in the Pathogenesis of Alzheimer's Disease Ralph Nixon and Panaiyur Mohan 15. Calpain and Apoptosis in the Immune System Margaret Squier and J. John Cohen 16. The Role of Calpain in Renal Proximal Tubular and Hepatocyte Injury Charles Edelstein and Robert Schrier 17. Calpains in the Lens of the Eye Thomas Shearer, Hong Ma, M.Shih, Chiho Fukiage and Mitsoyoshi Azuma 18. Calpain Activation and Expression in Toxicant Injury Susan Starcevic and Raymond Novak 19. Calpain 3 (p94) in Limb Girdle Muscular Dystrophy Type 2A Isabelle Richard, Jacques Beckmann and Michael Fardeau 20. Genetic Analysis of Calpain Isoform Function in Skeletal Muscle: New Stratagies to Study Protease Function Bor-rung Ou, Jing Huang, Neil Forsberg, Mohammad Ilian and Dong-hyun Hong 21. Crustacean Calcium-Dependent Proteinases Jill Beyette and Donald Mykles 22. Calpains in Drosophila and Mammals: Structure and Implications in Neuronal Function Peter Friedrich, Peter Tompa and Gaspar Jekely. Azuma, Senju Pharmaceutical Co., Japan, Naren Banik, Medical University of South Carolina, USA, Murad Bavbek, University of Virginia, USA, Jacques Beckmann, CNRS URA 1922, France, Elisa Beres, University of Virginia, USA, Jill Beyette, University of Cincinnati, USA, Helen Blanchard, National Research Council, Canada, Chris Boals, University of Virginia, USA, Mike Carson, University of Alabama, USA, Debasish Chattapadhyay, University of Alabama, USA, Rong-Ghi Chou, National Chia-Yi Institute of Agriculture, China, J. John Cohen, University of Colordo Health Sciences Centre, USA, Miroslaw Cygler, National Research Council, Canada, Charles Edelstein, University of Colorado, USA, John Elce, Queens University, Canada, Michel Fardeau, Hospital Salpetiere, Andrea Fergus, University of Virginia, USA, Neil Forsberg, Oregon State University, USA, Joan Fox, Cleveland Clinic Foundation, USA, Peter Friedrich, Hungarian Academy of Sciences, Chiho Fukiage, Senju Pharmaceutical Co., Japan, Darrell Goll, University of Arizona, USA, Pawel Grochulski, National Research Council, Canada, Rodney Guttmann, University of Alabama, USA, Ronald Hayes, University of Texas - Houstan Health Centre, USA, Edward Hogan, Medical University of South Carolina, USA, Dong-hyun Hong, University of Toronto, Canada, Jing Huang, Oregon State University, USA, Mohammad Ilian, Lincoln University, Gaspar Jekely, Hungarian Academy of Sciences, Gail Johnson, University of Alabama, USA, Andreas Kamfl, University of Insbruck, Austria, Sung-Don Kang, University of Virginia, USA, Richard Lane, Medical College of Ohio, USA, Kevin Lee, University of Virginia, USA, Guang-da Lin, University of Alabama, USA, Qin Lu, Medical College of Ohio, USA, Hong Ma, Oregon State University, USA, Masatoshi Maki, Nagoya University, Japan, Ronald Mellgren, Medical College of Ohio, USA, Panaiyur Mohan, New York University Medical Centre, USA, Donald Mykles, Colorado State University, USA, Sthanam Narayana, University of Alabama, USA, Ralph Nixon, New York University Medical Centre, USA, Raymond Novak, Wayne State University, USA, Yasuko Ono, University of Tokyo, Japan, Ahmed Ouali, Station de Recherches sur la Viade, France, Bor-rung Ou, Tunghai University, China, Rand M. Posmantur, Bristol-Myers Squibb Company, USA, Swapan Ray, Medical University of South Carolina, USA, Isabelle Richard, CNRS URA 1922, France, Takaomi Saido, RIKEN Brain Science Institute, Japan, Robert Schrier, University of Colorado, USA, Thomas Shearer, Oregon Health Sciences University, USA, Donald Shields, Medical University of South Carolina, M. Shih, Oregon Health Sciences University, USA, Hiroyuki Sorimachi, University of Tokyo, Japan, Margaret Squier, University of Colorado Health Sciences Centre, USA, Susan Starcevic, Wayne State University, USA, Koichi Suzuki, University of Tokyo, Japan, Emiko Takanao, Kyoto National Hospital, Japan, Richard Taylor, Institut National de la Recherche Agronomique, France, Valery Thompson, University of Arizona, USA, Peter Tompa, Hungarian Academy of Sciences, Kevin Wang, Warner Lambert Company, USA, Po-wai Yuen, Warner Lambert Company, USA, Wenli Zhang, Cornell University Medical College.

    1 in stock

    £228.00

  • The Essential Flower Essence Handbook - Revised Edition: Featuring the Original Spirit-in-Nature Essences Chosen by Doctors Across Borders to Train Their Physicians

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    £18.04

  • Functional Informatics in Drug Discovery

    Taylor & Francis Inc Functional Informatics in Drug Discovery

    1 in stock

    Book SynopsisIntegrating various technologies with informational systems provides vast improvements to the overall research and development that occur in the biopharmaceutical industry. One of the first books to explore this area, Functional Informatics in Drug Discovery examines all aspects of technology integration and information flow in a biopharmaceutical enterprise and outlines the specific technologies used at various stages of drug development. With contributions from leaders in academia, information technology, and the pharmaceutical industry, each chapter illustrates how a particular area of biological science can benefit from the tools of informatics. The book first looks at intelligent automation, neurally based computational tools, and pharmacodynamic (PD) biomarkers. It then reviews a variety of novel technologies and approaches presently used in drug discovery at Johnson & Johnson. The text also describes how informatics can advance antibody technology and drug development for oncology. After focusing on forward genetic and reverse genetic strategies to identify relevant target genes for drug discovery, the book explains proteomic expression profiling and explores the application of laser microdissection in transcriptomics.Taking a systematic approach, this volume examines the impact of informatics tools on various areas in biopharmaceuticals by presenting in-depth analyses of emerging trends and future opportunities.Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.Table of ContentsPreface. Intelligent Automation, Neurally Inspired Algorithms as Computational Tools. Using Pharmacodynamic Biomarkers to Accelerate Early Clinical Drug Development. Opportunities in CNS Drug Discovery and Development. Clinical Success of Antibody Therapeutics in Oncology. Relating Target Sequence to Biological Function. Use of Protein Microarrays for Molecular Network Analysis and Signal-Pathway Profiling. Laser Microdissection-Based Transcriptomics Using Microarrays. Index.

    1 in stock

    £161.50

  • Structural Genomics on Membrane Proteins

    Taylor & Francis Inc Structural Genomics on Membrane Proteins

    1 in stock

    Book SynopsisWhile the genomic revolution has quickly led to the deposit of more than 30,000 structures in the protein data bank (PDB), less than one percent of those contributions represent membrane proteins despite the fact that membrane proteins constitute some 20 percent of all proteins. This discrepancy becomes significantly troublesome when it is coupled with the fact that 60 percent of current drugs are based on targeting this group of proteins, a trend that does not seem likely to reverse.Structural Genomics on Membrane Proteins provides an excellent overview on novel research in bioinformatics and modeling on membranes, as well as the latest technological developments being employed in expression, purification, and crystallography to obtain high-resolution structures on membrane proteins. This cutting-edge work also explains the difficulties facing researchers—both technical and ethical—that have slowed the process. Structural Genomics on Membrane Proteins provides researchers with an unprecedented look at the novel technologies that will ultimately allow them to conquer the last frontier in structural biology, leading to accelerated breakthroughs in drug discovery.Table of ContentsIntroduction. Bioinformatics in Membrane Protein Analysis. Prokaryotic Membrane Transport Proteins: Amplified Expression and Purification. Membrane Protein Production Strategies for Structural Genomics. Refolding of Membrane Proteins for Large-scale Production. Crystallization of Membrane Proteins. Signaling through Membrane Proteins. Expression of Membrane Proteins in Yeasts. Expression of Functional Membrane Proteins in the Baculovirus-Insect Cell System: Challenges and Developments. Expression of Membrane Proteins in Mammalian Cells, Solubilization and Purification of Membrane Proteins. Fluorescent Labeling of Membrane Proteins in Living Cells. Membrane Protein NMR. Miniaturization of Structural Biology Technologies: From Expression to Biophysical Analyses. Electron and Atomic Force Microscopy of Reconstituted Membrane Proteins. Structural Genomics on Membrane Proteins. Molecular Modeling of Membrane Proteins. Towards Structural Bases for GPCR Ligand-binding: A Path for Drug Discovery.

    1 in stock

    £194.75

  • Alginates: Versatile Polymers in Biomedical

    Apple Academic Press Inc. Alginates: Versatile Polymers in Biomedical

    5 in stock

    Book SynopsisThis new volume explores the latest research on the use of alginate as a biopolymer in various biomedical applications and therapeutics. The uses of alginates and modified alginates discussed in this book include tissue regeneration, encapsulation and delivery of drugs, nucleic acid materials, proteins and peptides, genes, herbal therapeutic agents, nutraceuticals, and more. This book also describes the synthesis and characterizations of various alginate and modified alginate systems, such as hydrogels, gels, composites, nanoparticles, scaffolds, etc., used for the biomedical applications and therapeutics. Alginate, a biopolymer of natural origin, is of immense interest for its variety of applications in pharmaceuticals (as medical diagnostic aids) and in materials science. It is the one of the most abundant natural biopolymers and is considered an excellent excipient because of its non-toxic, stable, and biodegradable properties. Several research innovations have been made on applications of alginate in drug delivery and biomedicines. There needs to be a thorough understanding of the synthesis, purification, and characterization of alginates and its derivatives for their utility in healthcare fields, and this volume offers an abundance of information toward that end.Table of Contents1. Alginates: Source, Chemistry, and Properties 2. Recent Advances of Alginates as Material for Biomedical Applications 3. Alginates: Hydrogels, their Chemistry, and Applications 4. Alginate-Based Hydrogels: Synthesis, Characterization, and Biomedical Application 5. Chemically Modified Alginates for Advanced Biomedical Applications 6. Bionanocomposites of Alginates, their Chemistry, and Applications 7. Alginate and its Applications in Tissue Engineering 8. Alginate-Based Scaffolds in Bone Tissue Engineering Applications 9. Alginate Properties, Pharmaceutical and Tissue Engineering Applications 10. Alginate: Drug Delivery and Application 11. Chemical and Physical Modifications of Alginate to Improve their use as Carriers in Delivery Systems 12. Updates on Alginate-Based Interpenetrating Polymer Networks for Sustained Drug Release 13. Alginate Nanoparticles 14. Alginate-Based Nanocarriers in Modern Therapeutics 15. Alginate-Based Composites in Drug Delivery Applications 16. Hydroxyapatite-Alginate Composites in Drug Delivery 17. Alginate-Based Gastrointestinal Tract Drug Delivery Systems 18. Alginate Hydrogels as a Colon-Targeted Drug Delivery System 19. Alginate Carriers for Treatment of Ocular Diseases 20. Alginate Carriers for Bioactive Substances: Herbal Natural Compounds and Nucleic Acid Materials

    5 in stock

    £183.35

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