Oncology Books

Book SynopsisWritten primarily for mid-to-upper level undergraduates, this primer will introduce students to topics at the forefront of the subject that are being applied to probe biological problems, or to address the most pressing issues facing society. These topics will include those that form the cornerstone of contemporary research, helping students to make the transition to active researcher. This primer provides an overview of the complex processes underpinning cancer development and progression along with a summary of cancer treatment strategies, emphasising the development of targeted molecular therapies and the opportunities they provide.It takes a contemporary and integrated approach, encompassing debates on genetics, epigenetics, and cancer addictions, and highlighting the remaining challenges and future research directions to advance the field.Table of Contents1: Cancer Fundamentals 2: Pathology of Cancer 3: Molecular Epidemiology 4: Key Players and Pathways in Cancer 5: Cancer Treatment and Clinical Management 6: Major Challenges and New Opportunities in Cancer

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Book SynopsisThis new edition of the Practical Management of Complex Cancer Pain has been fully updated and expanded, with five new chapters on novel interventional techniques in cancer pain amelioration. The book provides advice on advanced pain management, emphasising the suitability and selection of patients for different invasive and complex procedures based on patient history. Case histories are included throughout the text to give the reader insight into the complexities of holistic management, with pain being only one component in the distress that cancer causes for both patients and families. The book also covers cancer pain management for patients in a community setting, and the collaboration between pain and palliative medicine. Concise, practical, and evidence-based, this guide is essential reading for all pain and palliative care specialists in the community, hospital, and hospice settings.Trade ReviewReview from previous edition Crisp and to the point. * Dr. Roger Woodruff, IAHPC Book Reviews *Winner of the BMA Medical Book of the Year Award 2015Table of ContentsA. Introduction and clinical cases 1: Michael Bennett: Definition and pathophysiology of complex cancer pain 2: Michael Bennett and Paul Farquhar Smith: Evidence based pharmacological approaches to management 3: Mahesh Choudhary: Neurolytic blocking agents 4: Paul Eldridge and Deepti Bhargava: Role of surgery in cancer pain management 5: Chinnamani Eswar: Oncological management of cancer pain 6: Arun Bhaskar: Pelvic pain 7: Manohar Sharma, Sanjeeva Gupta, and Lakshmi Vas: Chest wall pain from mesothelioma or lung cancer 8: Lakshmi Vas: Unilateral upper limb plexopathy pain caused by cancer 9: Kate Marley: Unilateral lower limb plexopathy related cancer pain 10: Hemkumar Pushparaj: Upper GI pain from invasive pancreatic cancer 11: Manohar Sharma and Sanjeeva Gupta: Multiple bone metastases/bone fracture related 12: JJohn Titterington, Louise Lynch, and Hemkumar Pushparaj: Intrathecal pump case history 13: Kate Marley and Manohar Sharma: Cancer survivor with pain progression B. Details of interventional techniques 14: Samyadev Datta: Basic procedure safety and patient considerations for cancer pain interventions 15: Dhanalakshmi Koyyalagunta and Arun Bhaskar: Sympathectomy for cancer pain 16: Kumar S V Das and Shubhabrata Biswas: Kyphoplasty and vertebroplasty for spinal metastasis pain 17: Manohar Sharma and Ashwin Vishwanathan: Cervical cordotomy (Fluroscopic and CT Guided technique) 18: John Titterington: Intrathecal drug delivery for cancer pain 19: Mahesh Chaudhari: Spinal neurolysis 20: Manohar Sharma and Lakshmi Vas: Interventions for head and neck cancer related pain 21: Paul Eldridge and Deepti Bhargava: Neurosurgical techniques for cancer pain 23: Dmitry Kruglov and Simon Thomson: Spinal cord stimulation for cancer related pain 24: Gaurav Sundar: Radiological tumour ablative techniques 25: Erlick Pereira and Abteen Mostafi: Radiofrequency brain lesioning for cancer related pain 26: Samyadev Datta: Radiofrequency ablation technique for metastatic spine disease 27: Mathew Brown: The role of High Intensity Focused Ultrasound (HIFU) in cancer pain management C. Collaboration between services 28: Kate Marley and Hemkumar Pushparaj: Role of collaboration between pain medicine and palliative care 29: Mathew Brown: Pain in cancer survivors 30: Eugene Choi, Priya Krishaswamy, and Umesh K. Gidwani: Control of complex pain at the end of life in hospice or community setting

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Book SynopsisMore and more people living with and beyond cancer seek integrative interventions to complement their conventional cancer care. This second edition of the highly successful Integrative Oncology provides the reader with the most updated information available with new chapters on Music and Expressive Arts Therapies, Naturopathic Oncology, and an integrative approach to Lung Cancer. Integrative medicine is defined as healing-oriented medicine that takes account of the whole person (body, mind, and spirit) as well as all aspects of lifestyle; it emphasizes the therapeutic relationship and makes use of appropriate therapies, both conventional and alternative. This series grows out of a need to organize and make accessible to clinicians the basic principles of integrative medicine in practical application to common health conditions. Each volume focuses on a particular specialty and features well-recognized and authoritative editors and chapter authors. The text is presented in an easy-to-read format featuring case histories, clinical pearls, and useful tables, with all key information highlighted. Series editor Andrew Weil, MD, is Professor and Director of the Arizona Center for Integrative Medicine at the University of Arizona. Dr. Weil''s program was the first such academic program in the U.S., and its stated goal is to combine the best ideas and practices of conventional and alternative medicine into cost effective treatments without embracing alternative practices uncritically.Trade ReviewIntegrative oncology is an exciting new discipline that offers best-practice methods to prevent cancer and support those affected by it on all levels: body, mind, and spirit. This comprehensive book provides meticulous, well-written chapters on proven and yet-to-be-proven methods for enhancing cancer care with integrative oncology. * The ASCO Post *Table of Contents1. Why Integrative Oncology? ; 2. An Integrative Approach to Cancer Prevention ; 3. Molecular Targets of Botanicals Used for Chemoprevention ; 4. Research Methodology Challenges in Integrative Oncology ; 5. Diet and Cancer: Epidemiology and Prevention ; 6. Nutritional Interventions in Cancer ; 7. Botanical Medicine in Integrative Oncology: What is Known? ; 8. Cannabinoids and Cancer ; 9. Botanical-Drug Interactions in Oncology - What Is Known? ; 10. The Antioxidant Debate ; 11. Physical Activity and Cancer ; 12. Massage Therapy ; 13. Mind-Body Medicine in Integrative Cancer Care ; 14. Music and Expressive Arts Therapies ; 15. Energy Medicine and Cancer ; 16. The Role of Spirituality ; 17. Naturopathic Oncology ; 18. Traditional and Modern Chinese Medicine ; 19. Ayurveda and Yoga for Cancer Supportive Care ; 20. Anthroposophic Medicine, Integrative Oncology, and Mistletoe Therapy of Cancer ; 21. Integrative Medicine and Breast Cancer ; 22. Prostate Cancer: An Integrative Approach ; 23. Integrative Medicine in Colorectal Cancer: Role of Energy Balance as Treatment ; 24. Lung Cancer: An Integrative Approach ; 25. Integrative Therapies in Cancer Symptom Management ; 26. Alternative Therapies as Primary Treatments for Cancer ; 27. Communication Issues in Integrative Oncology ; 28. Tending the Spirit in Cancer ; 29. A Patient's Perspective

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Book SynopsisThis practical pocketbook provides an overview of the role of HPV in the pathophysiology of cervical cancer and its current screening and management, the principles of immune control of HPV infection in cervical cancer, and the challenges of implementing HPV vaccines and future developments.Table of Contents1. The UK cervical screening programme ; 2. Management of cervical intraepithelial neoplasia (CIN) ; 3. Role of HPV in cervical carcinogenesis ; 4. HPV and genital cancer: the essential epidemiology ; 5. The role of HPV testing in cervical screening ; 6. Natural immune control of HPV infection ; 7. Prophylactic HPV vaccines: pre-clinical and proof of principle studies ; 8. Prophylactic HPV vaccination: current status ; 9. Introduction of HPV prophylactic vaccination ; 10. HPV vaccination in the developing world ; 11. Screening post vaccination ; 12. Second-generation HPV prophylactic vaccines ; 13. Therapeutic HPV vaccines ; 14. Conclusion

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Book SynopsisThis is the story of the discovery of the first human cancer virus. Through intriguing accounts that include some remarkable characters and individual stories from around the globe - including the UK, Africa, USA, and China - it tells the story of the Epstein-Barr virus and the understanding of its connections to a variety of other diseases.Trade Review[A] pithy, pacy study. * Nature *It reads like a thriller ... the book is compelling and colourful, capturing the romance of scientific discovery so well that it is exciting and accessible. * Linda Geddes, New Scientist *Table of ContentsAcknowledgements ; Preface ; Introduction ; 1. Out of Africa ; 2. The Eureka moment ; 3. Convincing the Sceptics ; 4. EBV in Africa - Burkitt lymphoma ; 5. EBV in Asia - Nasopharyngeal carcinoma ; 6. New Diseases - An accident of nature; an accident of medicine ; 7. Unexpected Arrivals ; 8. Prevention and Cure ; 9. Making Sense of a Human Cancer Virus ; References ; Further Reading ; Glossary ; Index

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Book SynopsisThe Oxford Handbook of Clinical Haematology provides core and concise information on the entire spectrum of blood disorders affecting both adults and children. Updated for its fourth edition, it includes all major advances in the specialty, including malignant haematology, haemato-oncology, coagulation, transfusion medicine, and red cell disorders, with a brand new chapter on rare diseases. Practically focused, and specifically designed for ease-of-use, and rapid access to the information you need, this handbook is an indispensable resource on all aspects of haematology for all trainee doctors, nurses, technicians, and research professionals.The handbook is divided into clinical approach and disease-specific areas. The clinical approach section outlines various symptoms and signs in patients with blood disease to enable the reader to formulate a sensible differential diagnosis beofre embarking on investigation and treatment. The disease-specific section is written by four authors whose expertise covers the whole breadth of diseases included in the book. All authors have contributed to national guidelines (e.g. British Committee for Standards in Haematology, BCSH) and are experts in the evidence base that exists for each topic. The Oxford Handbook of Clinical Haematology offers a concise and logical approach to caring for patients with diseases of the blood.Trade ReviewThis new edition follows the tradition of the highly respected Oxford medical handbook series which is a compact, well produced book brimming with knowledge that will help the clinician in a large number of situations. * Dr Harry Brown, glycosmedia.com *Table of Contents1. Clinical approach ; 2. Red cell disorders ; 3. White blood cell abnormalities ; 4. Leukaemia ; 5. Lymphoma ; 6. Myelodysplasia ; 7. Myeloproliferative neoplasms (MPNs) ; 8. Paraproteinaemias ; 9. Haematopoietic stem cell transplantation (SCT) ; 10. Haemostasis and thrombosis ; 11. Immunodeficiency ; 12. Paediatric haematology ; 13. Haematological emergencies ; 14. Supportive care ; 15. Protocols and procedures ; 16. Haematological investigations ; 17. Blood transfusion ; 18. Rare diseases ; A1 Haematology online ; A2 Charts and nomograms ; A3 Normal ranges

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Book SynopsisThe importance of spiritual well-being and the role of meaning in moderating depression, hopelessness and desire for death in terminally-ill cancer and AIDS patients has been well-supported by research, and has led many palliative clinicians to look beyond the role of antidepressant treatment in this population. Clinicians are focusing on the development of non-pharmacologic interventions that can address issues such as hopelessness, loss of meaning, and spiritual well-being in patients with advanced cancer at the end of life. This effort led to an exploration and analysis of the work of Viktor Frankl and his concepts of logotherapy, or meaning-based psychotherapy. While Frankl''s logotherapy was not designed for the treatment of patients with life-threatening illnesses, his concepts of meaning and spirituality have inspired applications in psychotherapeutic work with advanced cancer patients, many of whom seek guidance and help in dealing with issues of sustaining meaning, hope, and uTrade ReviewThis is a priceless resource for those working with patients with advanced cancer and other terminal illnesses. It expertly applies scientifically validated existential treatments in an accessible workbook format for busy practicing clinicians... Unlike so much literature on existential psychotherapy with its grand theories, this book shows how to work with dying patients step by step. Readers will be rewarded with a new-found confidence when working with dying patients... 5 stars! * Doody's Notes *Few would argue with the importance of helping patients sustain a sense of meaning, particularly in the last months of life as they confront death... Well, that's what these little treatment manuals are all about. A carefully developed and structured 8-week psychotherapeutic intervention, for individuals or groups, shown to be of benefit in randomized clinical trials... I was impressed by the potential value of these interventions. In the palliative care setting they could be facilitated by experienced nurses, social workers, counsellors, and pastoral care workers as well as physicians. * IAHPC News *Table of ContentsIntroduction: Treatment Overview ; a. General Guidelines ; b. Intervention Purpose and Goals ; c. Intervention Overview ; d. How to Use the Manual ; 1. Session 1. Concepts & Sources of Meaning: Introductions and Meaning ; 2. Session 2. Cancer & Meaning: Identity Before and After Cancer Diagnosis ; 3. Session 3. Historical Sources of Meaning: Life as Legacy that has been given [past] and Life as Legacy that one lives [present] and gives [future] ; 4. Session 4. Attitudinal Sources of Meaning: Encountering Life's Limitations ; 5. Session 5. Creative Sources of Meaning: 'Creativity, Courage & Responsibility ; 6. Session 6. Experiential Sources of Meaning: Connecting with Life ; 7. Session 7. Transitions: Reflection & Hopes for Future ; References ; Handouts ; Exercises ; Homework

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Book SynopsisUntil the early 1960s, cancer treatment consisted of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. This title explores how practitioners established a style of practice, at the center of which lies the clinical cancer trial.Trade Review"This remarkable book charts the emergence of a clinical field - medical oncology - for which experimental protocols have become routinized as a form of normal practice. Cancer on Trial will make a lasting contribution to the sociology of scientific knowledge, the history of clinical practice, and the understanding of the networked basis of biomedical research." (Jeremy A. Greene, Harvard University)"

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Book SynopsisDid America try to steal Soviet cancer secrets? And how could a cancer cure turn into a biological atom bomb? This tale of scientific discovery and politics investigates the ideological wrangling and conflicts within the Cold War search for a cure for cancer.Trade Review"A fascinating and seductively accessible account of medical science in Stalin's Russia, of the quest for a cure for cancer in the context of Cold War ideology, bureaucratic infighting, and disciplinary rivalries." - Charles Rosenberg, Harvard University

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Book SynopsisIs cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer germ, inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government's campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.

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Book SynopsisIn the 1960s, University of Cincinnati radiologist Eugene Saenger infamously conducted human experiments on patients with advanced cancer to examine how total body radiation could treat the disease. Using the Saenger case as a means to reconsider cold war medical trials, this book examines the tensions at the heart of clinical studies of the time.Trade Review"What is truly original about Contested Medicine is that, by using the science studies approach applied to a specific historical case, Kutcher shows not only how ethics were constitutive of the shape of experimental work on cancer at its inception but how both of these things were mutually changed over time." - Christopher Lawrence, Wellcome Trust Centre for the History of Medicine, University College London"

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Book SynopsisProvides a scathing critique of the chemotherapy culture as well as of unscientific "alternative" therapies and endorses molecularly based technologies, making it an illuminating and necessary read for anyone interested in cancer research, especially patients and their families and physicians.

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Book SynopsisMohs Micrographic Surgery, an advanced treatment procedure for skin cancer, offers the highest potential for recovery - even if the skin cancer has been previously treated. This procedure is a state-of-the-art treatment in which the physician serves as surgeon, pathologist, and reconstructive surgeon.

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Book Synopsis The 'Bible' (New York Times) and the 'seminal work' (LA Times) offering the most authoritative guidance through all stages of breast cancer diagnosis and recovery, fully revised and updated.   While the amount of information regarding a breast cancer diagnosis is vaster than ever, online and off, what continues to be missing is the explanation behind the options. Most of the data online on medical sites is generic and often comes from the same source. Then there are the patient sites as well as many social media outlets that provide peer to peer support and information. This is important for emotional support but still leaves out the full range of options and the reasons for them. The Breast Book is where people go for a deeper understanding of how to make the best possible choices for their particular situations. Now in its seventh edition, the Breast Book has been fully revised to incorpor

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Book SynopsisIn Knockout, Suzanne Somers interviews doctors who are successfully using the most innovative cancer treatments—treatments that build up the body rather than tear it down. Somers herself has stared cancer in the face, and a decade later she has conquered her fear and has emerged confident with the path she''s chosen.Now she shares her personal choices and outlines an array of options from doctors across the country: EFFECTIVE ALTERNATIVE TREATMENTS•without chemotherapy•without radiation•sometimes, even without surgery INTEGRATIVE PROTOCOLS•combining standard treatments with therapies that build up the immune system METHODS FOR MANAGING CANCER•outlining ways to truly live with the diease Since prevention is the best course, Somers'' experts provide nutrition, lifestyle, and dietary supplementation options to help protect you from getting the disease in the first place. Whichever path you choose, Knockout is a must-have resource to navigate the life-and-death world of cancer and increase your odds of survival.  After reading stunning testimonials from inspirational survivors using alternative treatments, you''ll be left with a feeling of empowerment and something every person who is touched by this disease needs…HOPE.

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Book SynopsisTable of Contents1 Front Matter; 2 OVERVIEW AND MAJOR RECOMMENDATIONS; 3 APPROACH TO THE STUDY; 4 DIET AND THE MECHANISMS OF CARCINOGENESIS; 5 EPIDEMIOLOGICAL METHODS; 6 LABORATORY METHODS; 7 MACROCONSTITUENTS; 8 VITAMINS, MINERALS, AND NONNUTRITIVE INHIBITORS OF CARCINOGENESIS; 9 FOOD ADDITIVES, CONTAMINANTS, CARCINOGENS, AND MUTAGENS; 10 CONSUMER BEHAVIOR; 11 REFERENCES; 12 APPENDICES; 13 APPENDIX A: COMMITTEE ON DIET, NUTRITION, AND CANCER--AFFILIATIONS AND MAJOR RESEARCH INTERESTS; 14 APPENDIX B: ACKNOWLEDGEMENTS

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Book SynopsisTrade Review"This comprehensive book closes the gap between the textbook and clinical practice. It answers the questions that physicists might initially have when trying to implement a new program, a new procedure, etc. The book will be a great reference for medical physics residents and junior physicists, as well as for physicists who are about to implement a new procedure. Medical residents can use the book to gain insights into the physics aspects of treatments. The authors have managed to distill the most important, currently available information to create a truly practical book on radiation oncology physics. This will be a valuable book for the radiation oncology team." -Sotirios Stathakis, PhD (University of Texas Health Sciences Center at San Antonio) Doody's Score: 98 - 5 StarsTable of ContentsPART I Building Blocks 1. Reference dosimetry for ionizing radiation 2. Relative dosimetry for MV beams 3. In-vivo dosimetry 4. Quality assurance and commissioning of new radiotherapy technology 5. Quality assurance of radiotherapy dose calculations 6. Immobilization techniques in radiotherapy 7. Image guidance and localization technologies for radiotherapy 8. Brachytherapy 9. Proton radiotherapy 10. Radiation safety and shielding in radiotherapy 11. Information Technology in Radiation Oncology 12. Quality and safety improvement in radiation oncology PART II Clinical Applications 13. Simulation for radiotherapy treatment planning 14. Treatment planning quality metrics 15. The use of electrons for external beam radiotherapy 16. IMRT and VMAT 17. SRS and SBRT 18. Clinical aspects of image guidance and localization in radiotherapy 19. Respiratory motion management for external beam radiotherapy 20. Intracavitary Brachytherapy 21. Interstitial Brachytherapy 22. Prostate seed implant 23. Intraoperative radiotherapy (IORT) 24. Special Procedures Appendix I Resource Documents Appendix II Glossary

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Book SynopsisTable of ContentsIsaacs: Hoffman and Abeloff's Hematology-Oncology Review 1. Cancer biology and Genomics 2. Tumor Immunology 3. Anti-Cancer Therapies SECTION 1: Chemotherapy SECTION 2: Immunotherapy, antibodies, vaccines and pathway inhibitors 4. Clinical Trial Design and Ethics 5. Hereditary Cancer Syndromes HEMATOLOGIC MALIGNANCIES 6. Acute Myeloid Leukemia and Myelodysplastic Syndrome 7. Myeloproliferative Disorders 8. Chronic Lymphocytic Leukemia, Hairy Cell Leukemia, and other Chronic Lymphoproliferative Disorders 9: Hodgkin lymphoma 10. Non-Hodgkin Lymphoma 11. Multiple myeloma and other plasma cell dyscrasias 12. T cell and NK cell neoplasms and other lymphoid malignancies 13. Hematopoeietic Cell Transplantation SOLID TUMOR MALIGNANCIES 14. Breast cancer a: Early Stage Breast Cancer b: Metastatic breast cancer e. Premalignant breast conditions and in situ disease 15. Lung Cancer a: Non-small cell lung cancer b: Small cell lung cancer 16. Other Thoracic Malignancies a: Mesothelioma b: Thymoma and thymic cancer 17. Head and Neck cancer 18 : Esophageal Cancer 19: Gastric cancer 20: Pancreatic cancer 21: Colorectal cancer and Anal Cancer 22: Hepatobiliary cancer 23: Neuroendocrine, small bowel and appendiceal malignancies 24. Prostate cancer 25. Bladder and other urothelial cancers 26. Renal Carcinomas 27. Germ cell tumors 28. Gynecological Malignancies Ovarian Cancer and Fallopian Tube Cancer Cancer of the Cervix, Uterus, Vagina, Vulva and Gestational Choriocarcinoma 29. Melanoma and other skin cancers 30. Bone and soft tissue sarcoma 31.Cancer of unknown primary site 32. . Malignancies of the Central Nervous System a. Primary b. Metastatic NONMALIGNANT HEMATOLOGIC CONDITIONS 33. Coagulation 34. Hematopoietic System 1: Hematopoietic System Disorders RBC or iron 35. Transfusion Medicine SURVIVORSHIP AND END OF LIFE CARE Chapter 36. Supportive Care

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Book SynopsisTable of ContentsAbeloff's Clinical Oncology Sixth Edition PART I: SCIENCE AND CLINCIAL ONCOLOGY SECTION A: BIOLOGY AND CANCER 1. Molecular Tools in Cancer Research 2. Intracellular Signaling 3. The Cellular Microenvironment and Metastases 4. Control of the Cell Cycle 5. The Pathophysiology of Cancer Cell Death 6. Cancer Immunology 7. Stem Cells, Cell Differentiation, and Cancer 8. Vascular and Interstitial Biology of Tumors 9. Cancer Metabolism SECTION B: GENESIS OF CANCER 10. Environmental Factors 11. DNA Damage Response Pathways and Cancer 12. Viruses and Human Cancer 13. Genetic Factors: Hereditary Cancer Predisposition Syndromes 14. Genetic and Epigenetic Changes in Cancer SECTION C: DIAGNOSIS OF CANCER 15. Pathology, Biomarkers, and Molecular Diagnostics 16. Imaging SECTION D: CLINICAL TRIALS 17. Biostatistics and Bioinformatics in Clinical Trials 18. Trial Design 19. Structures Supporting Cancer Clinical Trials 20. Oncology and Health Care Policy SECTION E: PREVENTION AND EARLY DETECTION 21. Discovery and Characterization of Cancer Genetic Susceptibility Alleles 22. Lifestyle and Cancer Prevention 23. Cancer Screening and Early Detection 24. Nicotine Dependence: Current Treatments and Future Directions SECTION F: TREATMENT 25. Cancer Pharmacology 26. Therapeutic Targeting of Cancer Cells: Era of Molecularly Targeted Agents 27. Basics of Radiation Therapy 28. Hematopoietic Stem Cell Transplantation 29. Gene Therapy in Oncology 30. Therapeutic Antibodies and Immunologic Conjugates 31. Complementary and Alternative Medicine PART II: PROBLEMS COMMON TO CANCER AND THERAPY SECTION A: HEMATOLOGIC PROBLEMS AND INFACTIONS 32. Disorders of Blood Cell Production in Clinical Oncology 33. Diagnosis, Treatment, and Prevention of Cancer-Related Venous Thrombosis 34. Infection in the Patient with Cancer SECTION B: SYMPTOM MANAGEMENT 35. Hypercalcemia 36. Tumor Lysis Syndrome 37. Cancer-Related Pain 38. Cancer Cachexia 39. Nausea and Vomiting SECTION C: TREATMENT COMPLICATIONS 40. Oral Complications 41. Dermatologic Toxicities of Anticancer Therapy 42. Cardiovascular Effects of Cancer Therapy 43. Reproductive Complications 44. Paraneoplastic Neurologic Syndromes 45. Neurologic complications 46. Endocrine Complications 47. Pulmonary Complications of Anticancer Treatment SECTION D: POST TREATMENT CONSIDERATIONS 48. Rehabilitation of Individuals with Cancer 49. Survivorship 50. Second Malignant Neoplasms 51. Caring for Patients at the End of Life SECTION E: LOCAL EFFECTS OF CANCER AND ITS METASTASIS 52. Acute Abdomen, Bowel Obstruction, and Fistula 53. Superior Vena Cava Syndrome 54. Spinal Cord Compression 55. Brain Metastases and Neoplastic Meningitis 56. Bone Metastases 57. Lung Metastases 58. Liver Metastases 59. Malignancy-Related Effusions SECTION F: SPECIAL POPULATIONS 60. Cancer in the Elderly: Biology, Prevention, and Treatment 61. Special Issues in Pregnancy 62. Human Immunodeficiency Virus (HIV) Infection and Cancer PART III: SPECIFIC MALIGNANCIES SECTION A 63. Cancer of the Central Nervous System SECTION B 64. Ocular Tumors 65. Cancer of the Head and Neck SECTION C: SKIN 66. Melanoma 67. Nonmelanoma Skin Cancers: Basal Cell and Squamous Cell Carcinomas SECTION D: ENDOCRINE 68. Cancer of the Endocrine System SECTION E: THORACIC 69. Cancer of the Lung: Non-Small Cell Lung Cancer and Small Cell Lung Cancer 70. Diseases of the Pleura and Mediastinum 71. Cancer of the Esophagus and Gastroesophageal Junction SECTION F: GASTROINTESTINAL 72. Cancer of the Stomach and Gastroesophageal Junction 73. Cancer of the Small Bowel 74. Colon Cancer 75. Cancer of the Rectum 76. Cancer of the Anal Canal 77. Liver and Bile Duct Cancer 78. Carcinoma of the Pancreas SECTION G: GENITOURINARY 79. Cancer of the Kidney 80. Carcinoma of the Bladder 81. Prostate Cancer 82. Cancer of the Penis 83. Testicular Cancer SECTION H: GYNECOLOGICAL 84. Cancers of the Cervix, Vulva, and Vagina 85. Cancer of the Endometrium 86. Ovaries and Fallopian Tubes 87. Gestational Trophoblastic Disease 88. Cancer of the Breast SECTION I: SARCOMAS 89. Sarcomas of Bone 90. Sarcomas of Soft Tissue SECTION J 91. Carcinoma of Unknown Primary SECTION K: PEDIATRICS 92. Pediatric Solid Tumors 93. Childhood Leukemia 94. Childhood Lymphoma SECTION L: HEMATOLOGICAL 95. Acute Leukemias in Adults 96. Myelodysplastic Syndromes 97. Myeloproliferative Disorders 98. Chronic Myeloid Leukemia 99. Chronic Lymphoid Leukemias 100. Hairy Cell Leukemia 101. Multiple Myeloma and Related Disorders 102. Hodgkin's Lymphoma 103. Non-Hodgkin Lymphoma 104. Cutaneous T-Cell Lymphoma and Cutaneous B-Cell Lymphoma 105. Adult T-Cell Leukemia-Lymphoma

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Book SynopsisTrade Review"a good friend for the wide pathology community" a good friend for the wide pathology communityTable of Contents1. Non-Neoplastic Lesions of the Nasal Cavity, Paranasal Sinuses, and Nasopharynx 2. Benign Neoplasms of the Nasal Cavity, Paranasal Sinuses, and Nasopharynx 3. Malignant Neoplasms of the Nasal Cavity, Paranasal Sinuses, and Nasopharynx 4. Non-Neoplastic Lesions of the Larynx, Hypopharynx, and Trachea 5. Benign Neoplasms of the Larynx, Hypopharynx, and Trachea 6. Malignant Neoplasms of the Larynx, Hypopharynx, and Trachea 7. Non-Neoplastic Lesions of the Oral Cavity 8. Benign Neoplasms of the Oral Cavity 9. Malignant Neoplasms of the Oral Cavity 10. Malignant Neoplasms of the Oropharynx 11. Non-Neoplastic Lesions of the Salivary Glands 12. Benign Neoplasms of the Salivary Glands 13. Malignant Neoplasms of the Salivary Glands 14. Non-Neoplastic Lesions of the Gnathic Bones 15. Benign Neoplasms of the Gnathic Bones 16. Malignant Neoplasms of the Gnathic Bones 17. Non-Neoplastic Lesions of the Ear and Temporal Bone 18. Benign Neoplasms of the Ear and Temporal Bone 19. Malignant Neoplasms of the Ear and Temporal Bone 20. Non-Neoplastic Lesions of the Neck (Soft Tissue, Bone, and Lymph Node) 21. Benign Neoplasms of the Neck (Soft Tissue, Bone, and Lymph Node) 22. Malignant Neoplasms of the Neck (Soft Tissue, Bone, and Lymph Node) 23. Non-Neoplastic Lesions of the Thyroid Gland 24. Benign Neoplasms of the Thyroid Gland 25. Malignant Neoplasms of the Thyroid Gland 26. Non-Neoplastic Lesions of the Parathyroid Gland 27. Benign Neoplasms of the Parathyroid Gland 28. Malignant Neoplasms of the Parathyroid Gland 29. Diseases of the Paraganglia System

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Book SynopsisTrade Review"this book belongs at the bookshelf (and tablet) of any pathologist getting acquainted with the systematic approach to the complex world of soft tissue tumours." This book belongs at the bookshelf (and tablet) of any pathologist getting acquainted with the systematic approach to the complex world of soft tissue tumours. "This excellent book could be considered as one of the key references in soft tissue pathology. It is a particularly excellent resource for pathology residents or fellows who are seeking a comprehensive but concise book on soft tissue pathology." Kyle Perry, MD (Henry Ford Health Systems) Doody's Score: 100-5 Stars!Table of Contents1. Introduction: Tumor Classification and Immunohistochemistry 2. Biologic Potential, Grading, Staging, and Reporting of Sarcomas 3. Spindle Cell Tumors of Adults 4. Pediatric Spindle Cell Tumors 5. Tumors with Myxoid Stroma 6. Epithelioid and Epithelial-like Tumors 7. Pleomorphic Sarcomas 8. Round Cell Tumors 9. Biphasic Tumors and Tumors with Mixed Patterns 10. Soft Tissue Tumors with Prominent Inflammatory Cells 11. Giant Cell-Rich Tumors 12. Adipocytic Tumors 13. Vascular Tumors 14. Cartilaginous and Osseous Soft Tissue Tumors 15. Cutaneous Mesenchymal Tumors 16. Mesenchymal Tumors of the Gastrointestinal Tract 17. Lower Genital Soft Tissue Tumors 18. Applications of Molecular Testing to Differential Diagnosis

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Book SynopsisTrade Review"Overall, this is an outstanding resource that everyone interested in this subject must have.. The main objective of this book and the well-thought-out content sets it apart from any other book in the same space." Reviewed by Ravi Salgia, MD, PhD (City of Hope) Doody's Score: 98, 5 Stars!Table of ContentsSection 1: Lung Cancer Control and Epidemiology 1. Classical Epidemiology 2. Tobacco Control and Primary Prevention 3. Tobacco Cessation 4. Non-Smoking Related Lung Cancer 5. Gender-Related Differences in Lung Cancer 6. Genetic Susceptibility to Lung Cancer 7. Early Detection and Radiologic Screening 8. Preclinical Biomarkers for The Early Detection of Lung Cancer 9. Chemoprevention of Lung Cancer: Present and Developing Technologies Section 2: Lung Cancer Molecular Carcinogenesis 10. Copy Number Abnormalities and Gene Rearrangements in Lung Cancer: Present and Developing Technologies 11. Mutational Events in Lung Cancer: Present and Developing Technologies 12. Epigenetic Events, Alterations, and Remodeling in Lung Cancer: Present and Developing Technologies 13. Stem Cells and Lung Cancer: In Vitro and In Vivo Studies 14. Microenvironment and Lung Cancer 15. MicroRNAs as Biomarkers for Lung Cancer Section 3: Immunology 16. Humoral and Cellular Immune Dysregulation and Lung Cancer Section 4: Pathology 17. Classic Anatomic Pathology and Lung Cancer 18. Molecular Testing and Lung Cancer 19. Management of the Small Biopsy in the Molecular Er Section 5: Clinical and Radiologic Presentation of Lung Cancer 20. Clinical Presentation 21. Conventional Imaging Lung Cancer 22. PET Imaging of Lung Cancer Section 6: Diagnosis and Staging of Lung Cancer 23. Diagnostic Work-Up of Suspected Lung Cancer 24. Surgical Staging of the Mediastinum including Mediastinoscopy and Thoracoscopy, Preoperative and Intraoperative 25. The 8th Edition of the Tumor, Node and Metastasis Classification of Lung Cancer Section 7: Surgical Management of Lung Cancer 26. Preoperative Functional Evaluation of the Surgical Candidate 27. Results of Video Assisted Techniques for Resection of Lung Cancer 28. Results of Robotic Techniques for Resection of Lung Cancer 29. Extent of Surgical Resection for Stage I and II Lung Cancer 30. Extended Resections for Lung Cancer: Chest Wall and Pancoast Tumors 31. Extended Resections for Lung Cancer: Broncho/Vascular Sleeve Resections 32. Multiple Nodules: Management of the Patient with Synchronous or Metachronous Lung Cancers 33. Surgical Management of the Marginally Resectable Patient Section 8: Radiotherapeutic Management of Lung Cancer 34. Technical Requirements for Lung Cancer Radiotherapy 35. Radiobiology of Lung Cancer 36. Patient Selection for Radiotherapy 37. Stage I Non-Small Cell Lung Cancer and Oligometastatic Disease 38. Ablation Options for Localized Lung Cancer 39. Radiotherapy for Locally Advanced Non-Small Cell Lung Cancer, including Combined Modality 40. Radiotherapy in the Management of Small Cell Lung Cancer: Thoracic Radiotherapy, Prophylactic Cranial Irradiation 41. Palliative Radiotherapy for Lung Cancer: Locoregional and Metastatic 42. Acute and Late Toxicities of Thoracic Radiotherapy: Pulmonary, Esophagus, Heart 43. Treatment-Related Neurotoxicity, Medical and Radiation Therapy Section 9: Chemotherapy and Targeted Agents for Lung Cancer 44. Front-Line Systemic Options in Non-Small Cell Lung Cancer 45. Systemic Options in Second Line and Beyond 46. Maintenance Therapy in NSCLC 47. Pharmacogenomics and Lung Cancer 48. New Targetable Pathways in Lung Cancer 49. Management of Toxicities of Targeted Therapies 50. Immunotherapy and Lung Cancer 51. Systemic Therapy in Early-Stage NSCLC 52. Treatment of Small-Cell Lung Cancer Section 10: Other Thoracic Malignancies 53. Malignant Mesothelioma 54. Mediastinal Tumors 55. Neuroendocrine Tumors of the Lung Other than SCLC 56. Thymic Cancer/Thymoma Section 11: Symptom Management and Complications 57. Lung Cancer Emergencies 58. Role of Palliative Care in Lung Cancer Section 12: Clinical Trials 59. Methodology of Clinical Trials in Lung Cancer 60. How to Promote and Organize Clinical Research in Lung Cancer Section 13: Thoracic Oncology Advocacy 61. Role of Advocacy Groups in Lung Cancer 62. Health Services Research in Lung Cancer Appendix 63. Appendix: Diagnostic Algorithms

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Book SynopsisTable of ContentsSECTION 1 Fluid and Electrolyte Disorders in Cancer Patients 1 Kidney Function 2 Dysnatremias in Cancer 3 Potassium Disorders 4 Calcium and Phosphorus Disorders 5 Volume Disorders and Fluid Resuscitation SECTION 2 Paraprotein-Related Kidney Diseases 6 Paraproteins 7 Cast Nephropathy 8 Systemic Light Chain Amyloidosis 9 Monoclonal Immunoglobulin Deposition Disease 10 Fibrillary and Immunotactoid Glomerulonephritis SECTION 3 Hematopoietic Stem Cell Associated Kidney Disease 11 Hematopoietic Cell Transplant Associated Kidney Injury 12 Sinusoidal Obstruction Syndrome 13 Thrombotic Microangiopathy 14 Graft-Versus-Host Disease 15 Chronic Kidney Disease, End-Stage Renal Disease, and Bone Marrow Transplant SECTION 4 Chemotherapy and Radiation Related Kidney Diseases 16 Conventional Chemotherapy 17 Targeted Cancer Therapies (Biologics) 18 Adverse Kidney Effects of Immunotherapies 19 Chemotherapy in Chronic Kidney Disease and Dialysis 20 Radiation Nephropathy SECTION 5 Paraneoplastic Glomerulopathies 21 Paraneoplastic Glomerular Diseases 22 Paraneoplastic Glomerulonephritis 23 Hematologic Malignancies 24 Cancer Screening Recommendations SECTION 6 Renal Tumors 25 Renal Cell Cancer 26 Wilms Tumor and von Hippel Lindau Disease 27 Tuberous Sclerosis Complex and the Kidney 28 Evaluation of a Renal Cyst/Mass SECTION 7 Acute Kidney Injury 29 Acute Kidney Injury Incidence, Pathogenesis, and Outcomes 30 Tumor Lysis Syndrome 31 Obstructive Nephropathy in Cancer 32 Renal Replacement Therapies SECTION 8 Chronic Kidney Disease and Cancer 33 Chronic Kidney Disease as a Complication of Cancer, With Special Focus on Kidney and Urothelial Tumors 34 Incidence of Cancer and Screening Recommendations 35 Cancer in Renal Transplant Patients SECTION 9 Kidney Infections 36 Renal Infections in Cancer Patients SECTION 10 Infiltrative Diseases 37 Kidney Disease in Leukemia 38 Kidney Disease in Lymphoma

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Book SynopsisTable of ContentsPart 1. Cytotoxic Chemotherapy 1. Mechanism of Chemotherapy in Cancer Treatment 2. Neutropenic Complications of Chemotherapy 3. Chemotherapy Induced Anemia 4. Cancer Treatment Related Thrombocytopenia 5. Oral Mucositis 6. Gastrointestinal Complications of Chemotherapy 7. Neurological Complications 8. Pulmonary Toxicities of Cytotoxic Chemotherapy 9. Dermatological Complications of Chemotherapy 10. Cardiotoxicities of Chemotherapy 11. Management of Cancer Treatment Infusion Reactions Part 2. Targeted Therapies 12. Mechanism of Targeted Therapies in Cancer Treatment 13. Gastrointestinal Complications 14. Pulmonary Toxicities of Molecular Targeted Therapies 15. Dermatologic Toxicities 16. Cardiotoxicities Part 3. Immunotherapies 17. Mechanism of Immune-Related Adverse Events 18. Endocrine Toxicities 19. Gastrointestinal Toxicities 20. Neurological Complications of Immunotherapy 21. Pulmonary Toxicities 22. Dermatological Complications 23. Immunotherapy-Induced Cardiotoxicities 24. Rheumatological Complications Part 4. Radiation Therapy 25. Mechanisms of Radiation-Related Toxicities 26. Radiation-Induced Mucositis and Esophagitis 27. Radiation Therapy Related Dermatologic Toxicities 28. Pulmonary Toxicity from Radiation Therapy 29. Radiation-Induced Cardiotoxicities

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Book SynopsisTable of ContentsSECTION I SCIENTIFIC FOUNDATIONS OF RADIATION ONCOLOGY Part A. Radiobiology 1. The Biological Basis of Radiation Oncology 2. Molecular and Cellular Biology 3. Dose-Response Modifiers in Radiation Therapy 4. Interaction of Chemotherapy and Radiation 5. Biologics and Their Interactions with Radiation Part B. Physics 6. Radiation Oncology Physics 7. Radiation Physics - Stereotactic Part C. Related Cancer Disciplines 8. Surgical Principles 9. Principles of Chemotherapy 10. Imaging in Oncology 11. Nuclear Medicine 12. Health Services Research in Radiation Oncology 13. Statistics and Clinical Trials 14. Late Effects after Radiation SECTION II TECHNIQUES AND MODALITIES 15. Brachytherapy 16. Intensity-Modulated and Image-Guided Radiation Therapy 17. Intraoperative Irradiation 18. Total Body Irradiation 19. Charged Particle Radiotherapy 20. Neutron Radiotherapy 21. Hyperthermia 22. Targeted Radionuclide Therapy 23. Stereotactic Irradiation: CNS Tumors 24. Stereotactic Body Irradiation: Extracranial Tumors 25. Metastatic Disease: Bone, Spinal Cord, Brain, Liver, and Lung SECTION III DISEASE SITES Part A. Central Nervous System Tumors Overview 26. Low-Grade Gliomas 27. High-Grade Gliomas 28. Benign Brain Tumors: Meningiomas and Vestibular Schwannomas 29. Pituitary Tumors and Craniopharyngiomas 30. Spinal Cord Tumors 31. Orbital, Ocular, and Optic Nerve Tumors Part B. Head and Neck Tumors Overview 32. Oral Cavity 33. Oropharyngeal Cancer 34. Nasopharyngeal Carcinoma 35. Larynx and Hypopharynx Cancer 36. Sinonasal Cancer 37. Salivary Gland Malignancies 38. Thyroid Cancer 39. Unknown Head and Neck Primary Site 40. Management of the Neck 41. Cutaneous Carcinoma 42. Malignant Melanoma Part C. Thoracic Neoplasms Overview 43. Small Cell Lung Cancer 44. Non-Small Cell Lung Cancer 45. Cancer of the Esophagus 46. Uncommon Thoracic Tumors Part D. Gastrointestinal Tumors Overview 47. Gastric/GE Junction Cancer 48. Pancreatic Cancer 49. Hepatobiliary Cancer 50. Colon Cancer 51. Rectal Cancer 52. Anal Carcinoma Part E. Genitourinary Tumors Overview 53. Prostate Cancer 54. Bladder Cancer 55. Testicular Cancer 56. Kidney and Ureteral Carcinoma 57. Penile Cancer Part F. Gynecologic Tumors Overview 58. Cervical Cancer 59. Endometrial Cancer 60. Cancers of the Vulva and Vagina 61. Ovarian Cancer Part G. Breast Cancer Overview 62. Noninvasive Breast Cancer 63. Breast Cancer: Stages I-II 64. Breast Cancer: Postmastectomy Radiation, Locally Advanced Disease, and Inflammatory Breast Cancer Part H. Sarcoma and Benign Disease 65. Soft Tissue Sarcoma 66. Benign Diseases Part I. Childhood Cancers Overview 67. Central Nervous System Tumors 68. Pediatric Soft Tissue Sarcomas 69. Pediatric Sarcomas of Bone 70. Wilms' Tumor 71. Retinoblastoma 72. Neuroblastoma 73. Pediatric Leukemias and Lymphomas 74. Pediatric Hodgkin's Lymphoma 75. Rare Pediatric Tumors Part J. Lymphoma and Hematologic Malignancies Overview 76. Hodgkin's Lymphoma 77. Non-Hodgkin's Lymphoma 78. Multiple Myeloma and Other Plasma Cell Neoplasms 79. Mycosis Fungoides

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Book SynopsisTable of Contents1 A Multidisciplinary Approach to Cancer: A Radiologist's View 2 A Multidisciplinary Approach to Cancer: A Surgeon's View 3 A Multidisciplinary Approach to Cancer: A Medical Oncologist's View 4 A Multidisciplinary Approach to Cancer: A Radiation Oncologist's View 5 Assessing Response to Therapy 6 Head and Neck Cancer 7 Lung Cancer 8 Primary Mediastinal Neoplasms 9 Pleural Tumors 10 Liver Cancer: Hepatocellular and Fibrolamellar Carcinoma 11 Cholangiocarcinoma 12 Pancreatic Ductal Adenocarcinoma 13 Cystic Pancreatic Lesions 14 Pancreatic Neuroendocrine Tumors 15 Esophageal Cancer 16 Gastric Carcinoma 17 Small Bowel Malignant Tumors 18 Colorectal Cancer 19 Renal Tumors 20 Urothelial Carcinoma (Bladder Cancer and Upper Tracts) 21 Testicular Germ Cell Tumors 22 Primary Adrenal Malignancy 23 Prostate Cancer 24 Primary Retroperitoneal Tumors 25 Tumors of the Uterine Corpus 26 Cervical Cancer 27 Ovarian Cancer 28 Breast Cancer 29 Myeloma and Leukemia 30 Hematologic Malignancy: The Lymphomas 31 Thoracic Metastatic Disease 32 Metastases Abdominal-Pelvic Organs 33 Peritoneal Cavity and Gastrointestinal Tract 34 Bone Metastases 35 Cancer of Unknown Primary 36 Imaging in Thyroid Cancer 37 Melanoma 38 Soft Tissue Sarcomas 39 Interventional Imaging in the Oncologic Patient 40 Complications in the Oncologic Patient: Chest 41 Complications in the Oncologic Patient: Abdomen and Pelvis 42 Pulmonary Embolic Disease and Cardiac Masses and Tumors 43 Protocols for Imaging Studies in the Oncologic Patient 44 Front Matter

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Book SynopsisTable of Contents1 Lung Cancer Screening and Prevention 2 Lung Cancer: Diagnostic Techniques 3 Histology and Molecular Testing 4 Surgical Considerations in Lung Cancer Treatment 5 Surgically Resectable Disease 6 Oligometastatic Disease 7 Locally Advanced Non-Small Cell Lung Cancer 8 First-Line Therapy 9 Second-Line Therapy in Advanced Non-Small Cell Lung Cancer 10 Epidermal Growth Factor Receptor-Mutated Non-Small Cell Lung Cancer: A Clinical Approach 11 Diagnosis and Treatment of Anaplastic Lymphoma Kinase (ALK)Rearranged Non2Small Cell Lung Cancer 12 Other Molecular Cohorts Including ROS1, BRAF, HER2, MET, NTRK, RET, KRAS 13 Immunotherapy 14 Small Cell Lung Cancer Index

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Table of ContentsDedication Adrian Cristian Preface Adrian Cristian Section I 1. Cascade of disability in Breast Cancer and Gynecologic Cancer-assessment and treatment Adrian Cristian 2. Practice Implementation and Outcomes Measurement Nicole L. Stout 3. Exercise while living with Breast and Gynecologic Cancer Susan Maltser and Carly Rothman 4. Cancer Related Fatigue in Breast and Gynecologic Cancer Jasmine Zheng and Betty Chernack 5. Nutritional rehabilitation of the Breast and Gynecologic Cancer patient Karla Otero, Claudia Ferri and Carla Araya 6. A Comprehensive Approach to Psychosocial Distress and Anxiety in Breast and Gynecological Cancer Sherry Hite 7. Prehabilitation in Breast and Gynecologic Oncology Sasha E. Knowlton Section II 8. Systemic therapy for the Treatment of Breast Cancer Ana Cristina Sandoval Leon and Angelique Richardson 9. Principles of Radiation Therapy in Breast Cancer Maria Amelia Rodrigues 10. Breast Cancer Surgery Jane Mendez 11. Reconstructive Surgery and Post-Operative Care for Breast Cancer Harry Michael Salinas, Miguel Medina and Austin Jacob Pourmoussa 12. Skeletal Metastasis in Breast Cancer Theresa Pazionis 13. Shoulder Dysfunction in Breast Cancer Diana Molinares and Adrian Cristian 14. The role of Interventional Pain Management in Breast Cancer Ashish Khanna 15. Aromatase Inhibitor Musculoskeletal Syndrome Jonas Sokolof and Monica Gibilisco Section III 16. Systemic Therapy for the Treatment of Gynecologic Malignancies John Paul Diaz 17. Principles of Radiation Therapy in Gynecologic Cancer Allie Garcia-Serra 18. Surgical Gynecologic Oncolcogy Nicholas C. Lambrou and Angel Amadeo 19. Pelvic Floor Dysfunction in Gynecologic Cancer Louise Van Voorhis Gleason Section IV 20. Cancer Related Cognitive Impairment-Diagnosis, pathogenesis and management Beatriz Currier, Aileen Moreno and Richard A. Hamilton 21. Lymphedema in Breast and Gynecologic Cancer Mary Crosswell and Adrian Cristian 22. Peripheral Nervous System Involvement in Breast and Gynecologic Cancer Christian M. Custodio and Franchesca Konig 23. Inpatient Rehabilitation of Patients with Breast Cancer and Gynecologic Cancer Terence Pugh 24. Palliative Care and Symptom Management in Breast and Gynecologic Cancer Marianna Khawand and Suleyki Medina 25. Reproductive Issues and Fertility in Breast and Gynecologic Cancer John Paul Diaz and Elina Melik-Levine 26. Oncology Massage Therapy in Breast and Gynecologic Cancer Kristen Galamaga

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Table of ContentsNeurosurgical Approaches to the Skull Base: A Guide for the RadiologistAnterior and Central Skull Base Tumors: Key Points for the Radiologist to Analyze Prior to Endoscopic ApproachesImaging of the Vestibular Schwannoma: Diagnosis, Monitoring, and Treatment PlanningPatterns of Perineural Skull Base Tumor Extension from Extracranial TumorsImaging of Trigeminal Neuralgia and Other Facial PainImaging of Acquired Skull Base Cerebrospinal Fluid LeaksImaging of Petrous Apex LesionsImaging of Sella and Parasellar RegionImaging Anatomy and Pathology of the Intracranial and Intratemporal Facial NerveImaging of Acute and Chronic Skull Base InfectionImaging of Skull Base Trauma: Fracture Patterns and Soft Tissue InjuriesImaging of Developmental Skull Base AbnormalitiesSkull Base Neurointerventional TechniquesNew and Advanced Magnetic Resonance Imaging Diagnostic Imaging Techniques in theEvaluation of Cranial Nerves and the Skull Base

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Book SynopsisTrade Review"This book provides a comprehensive overview of the clinical management of various gynecologic conditions. This tenth edition updates the previous version, which was published in 2018." ©Doody's Review Service, 2023, Sydney P Oesch, MD (University of Texas Southwestern Medical Center) Doody's Score: 4 Stars!Table of Contents1) Pre Invasive Disease of the Cervix a. Stu Massad 2) Pre Invasive Disease of the Vagina and Vulva and related disorders a. Cara Matthews and Joan Walker 3) Invasive Cervical Cancer a. Krish Tewari and Brad Monk 4) Endometrial Hyperplasia, Estrogen Therapy, and the Prevention of Endometrial Cancer a. Lisa Landrum and Rosemary Zuna and Joan Walker 5) Adenocarcinoma of the Uterine Corpus a. William Creasman and David Scott Miller 6) Sarcoma of the Uterus a. Scott McMeeken and William Creasman 7) Gestational Trophoblastic Disease a. Emma Barber and John Soper 8) Invasive Cancer of Vulva a. Thomas Herzog 9) Invasive Cancer of the Vagina a. Marilyn Huang, Brian Slomovitz and Rob Coleman 10) Adnexal Masses a. Camille Gunderson and Robert Mannel 11) Epithelial Ovarian Cancer a. Eric Eisenhauer, Ritu Salani and Larry Copeland 12) Germ Cell, Stromal and other ovarian tumors a. Emily Pennock, Chad Hamilton, Larr Maxwell and Charlotte Marcus 13) Fallopian tube cancer a. Eric Hope, G Larry Maxwell, and Chad Hamilton 14) Breast Diseases a. Patricia Cronin and Mary Gemignani 15) Cancer in Pregnancy a. Krish Tewari 16) Complications of Disease and Therapy a. Kemi Doll and Dan Clarkepearson 17) Basic Principles of Chemotherapy a. Christina Chu and Steve Rubin 18) Targeted therapy and Molecular Genetics a. Shannon Westin, Anil Sood and Rob Coleman 19) Genes and Cancer: Genetic Counselling and Clinical Management a. David Mutch, Sheri Babb and Phil Disaia 20) Palliative Care and Quality of Life a. Dana Chase, Siu-Fun Wong, Lari Wenzel and Brad Monk 21) Role of Minimally Invasive surgery in Gynecologic Malignancies a. Floor Backes, David Cohn, Robert Mannel and Jeff Fowler 22) Epidemiology of Commonly Used Statistical Terms and Analysis of Clinical Studies a. Wendy Brewster 23) Basic Principles in Gynecologic Radiotherapy a. Catheryn Yashar Appendix A: Staging: Staging of Cancer at Gynecologic Sites a) Mutch B: Modified from Common Terminology Criteria for Adverse events (common terminology criteria for adverse events). C: Blood component therapy D: Suggested recommendations for routine cancer screening E: Nutritional Therapy: Index

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Book SynopsisTable of ContentsIntroduction A- Basics of breast diffusion MRI - General principles and challenges of diffusion MRI (Le Bihan, Iima, Partridge) This section will provide the physical basis of Diffusion MRI, give the key concepts necessary to understand and use DWI in clinical practice B- Breast Clinical Applications - Overview of conventional breast imaging (MMG, US, MRI except DWI) (Mann and/or Kuhl) This chapter will give a general overview of the field of breast imaging, with pros and cons, to help positioning DWI among all other approaches - Overview of breast DWI: Diagnosis of suspicious lesions using DWI in combination with standard MRI (20 pages) (Baltzer, Clauser, Gilbert) This chapter will review how DWI is currently used as a breast imaging modality and how breast lesions appear with DWI - Biomarkers, prognosis and prediction factors (10 pages) (Iima, Moy) This chapter will explain how DWI could be specifically used to provide information on prognosis and prediction factors (eg Her, Pg, ER, Ki67 receptors expression) and help lesion management - Disease and treatment monitoring (10 pages) (Partridge, Hylton, Li) This chapter will provide guidance on how DWI can be used to manage breast lesions, from diagnosis to treatment monitoring, using examples for most common types of lesions - Diffusion MRI as a stand-alone unenhanced breast imaging approach and screening (10 pages) (Amornsiripanitch, Hee Jung Shin, Partridge) This chapter will foresee how DWI could be used as a stand-alone approach (without DCE): patient population, technical requirement - DWI and breast physiology status (menstrual cycle, pregnancy, lactation) (10 pages) (Iima, Nissan) This chapter will review how changes in hormonal context and physiology may affect appearance of DWI normal breast tissues and lesions C- Challenges and Advanced Techniques - IVIM/perfusion Non-Gaussian diffusion (20 pages) (Sigmund, Iima, Le Bihan) This chapter will show how tissue microcirculation (perfusion) can be obtained from DWI without the need for tracers or contrast agent, explain why boosting sensitivity to diffusion provides added contrast and information on tissue microstructure, and how to combine both approaches in a clinical setting - DTI (20 pages) (Sigmund, Partridge) This chapter will explain how Diffusion Tensor Imaging could potentially reveal oriented features in the breast (eg ducts) and how lesions might modify them - Tissue characterization, radiomics, Artificial Intelligence, multiparametric imaging and integration of diffusion MRI to BIRADS (20 pages) (Pinker, Morris) This chapter will explain how DWI could be combined to other advanced breast imaging approaches to provide higher sensitivity, specificity and prognosis - Novel/Alternative Acquisition Techniques - (20 pages) o DWIBS (Takahara) o MS-EPI, RS-EPI, SMS, RSI, etc - (Hargreaves) Those short chapters will provide glances at novel or alternative methods to perform DWI with specific focus for breast applications D- Let us get practical - Clinical interpretation of diffusion MRI, ROI assessment, common errors, pitfalls and artifacts, challenges in acquisition (20 pages) (Gilbert, Patterson) This chapter will provide guidance on the interpretation of DWI in the breast, qualitatively and quantitatively, showing how common errors can be avoided and artifacts corrected - Quality control, standardization, test-objects (20 pages) (Chenevert, Newitt, Malyarenko, Keenan) This chapter will provide guidance on how to optimize DWI protocols, verify and control settings to obtain accurate and reproducible results

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Book SynopsisTable of ContentsPart One Introduction Ch 1 Evolution of HCT, past, present, and future Ch 2 Human leukocyte antigen Ch 3 Introduction and basic science of chimeric antigen receptor therapies Ch 4 Statistical methods in HCT and cellular therapies Part Two Methodology Ch 5 Hematopoietic cell collection; bone marrow harvesting, apheresis, UCB Ch 6 Leukapheresis and manufacturing of CAR cells Part Three General Clinical Aspects Ch 7 Patient and donor selection and preparing for HCT Ch 8 General management of patients undergoing HCT Ch 9 Haploidentical HCT Ch 10 Umbilical cord blood transplantation Ch 11 Process and general management of patients undergoing CAR therapies Part Four Pharmacology and Radiation Therapy Ch 12 Preparative regimens used in HCT and CAR therapies Ch 13 Pharmacology of drugs used in HCT and CAR therapies Ch 14 Role of radiation therapy in HCT and CAR therapies Part Five Disease-Specific Indications and Results Ch 15 HCT in AML Ch 16 CAR therapy in AML Ch 17 HCT in ALL Ch 18 CAR therapy in ALL Ch 19 HCT in chronic leukemias; CML and CLL Ch 20 HCT in MDS Ch 21 HCT in myeloproliferative disorders Ch 22 HCT in aplastic anemia Ch 23 HCT in multiple myeloma Ch 24 CAR therapy in multiple myeloma Ch 25 HCT in light-chain amyloidosis Ch 26 HCT in NHL Ch 27 HCT in Hodgkin lymphoma Ch 28 CAR therapy in lymphoma Ch 29 HCT in rare malignancies Ch 30 HCT for hematologic malignancies in HIV patients Ch 31 HCT in solid tumors Part Six Prevention and Management of Complications Ch 32 Infectious complications Ch 33 Graft failure Ch 34 Graft-versus-host disease Ch 35 Miscellaneous complications of HCT Ch 36 Cytokine release syndrome Ch 37 Neurologic complications of CAR therapy (ICANS) Ch 38 Miscellaneous complications of CAR therapy Ch 39 Symptoms management and palliative care Ch 40 Survivorship

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Book SynopsisTrade Review"This is an easy-to-read resource on rare gynecological cancers for those in the field. Each chapter is comprehensive and self-standing, preventing flipping back and forth to other chapters to find pertinent material. There are useful figures and tables to summarize the content and to give an at-a-glance, quick view of the key information covered in the chapter. The book is very up to date and addresses all therapies that are currently used in gynecological cancers.The ebook is easy to navigate and provides access to the book in its entirety." ©Doody's Review Service, 2023, Dandi Huang, MD(Cedars-Sinai Medical Center). Doody's Score: 4 Stars!Table of ContentsContributor Information: Please list names/affiliations of any contributors (can be tentative): Section 1 - Ovarian Cancer Malignant Germ Cell Tumors Sex Cord-Stromal Tumors Malignant Mixed Mesodermal Tumor Clear Cell Carcinoma Mucinous Carcinomas Low-Grade Serous Tumors (MPSC) and Variants Small Cell (hypercalcemic) Other rare ovarian cancers (Small Cell Carcinoma (hypercalcemic), Small Cell Carcinoma (Neuroendocrine, Mesolthelioma, Squamous Cell, Sarcomas) Section 2 - Uterine Cancer Leiomyosarcoma Other sarcomas of the uterus (Endometrial Stromal Sarcoma, STUMP, adenosarcoma) Carcinosarcoma Uterine Serous Carcinoma Other rare uterine cancers (Choriocarcinoma, Yolk Sac, Neuroendocrine) Section 3 - Cervical Cancer High Grade Neuroendocrine Carcinoma Other rare cervical cancers (Verrucous Carcinoma, Clear Cell Carcinoma, Adenoid Cystic Carcinoma, Rhabdomyosarcoma) Section 4 - Vulvovaginal Cancers Clear Cell Carcinoma Melanoma Bartholin Gland Carcinoma Benign and Malignant Paget's Disease Other rare vulvovaginal carcinomas (Verrucous Carcinoma, Embryonal Rhabdomyosarcoma, Yolk Sac Tumor, Aggressive Angiomyxoma, Sarcomas Section 5 - Trophoblastic Disease Gestational Trophoblastic Disease and Placental Site Trophoblastic Tumor

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Book SynopsisTrade Review"This book addresses palliative care in radiation oncology from a multi-dimensional perspective and includes an ebook component. The website resources provide quick links to cited references, but offer limited additional features beyond the convenience of expanded access to the book." ©Doody's Review Service, 2023, Mark D. Hurwitz, MD (New York Medical College) Doody's Score: 4 Stars!Table of ContentsSECTION I Foundations and Principles of Palliative Care in Oncology 1 Definition of Palliative Care 2 Introduction to Prognostication 3 Basic Communication Frameworks 4 Troubleshooting Difficult Conversation 5 Models of Multidisciplinary Management SECTION II Techniques and Modalities 6 Palliative Radiation 7 Selecting Modalities 8 Treatment Planning in Palliative Radiotherapy 9 Alternate Modalities for Palliation 10 Combining Radiation and Systemic Therapy 11 Considerations Involving Reirradiation SECTION III Foundations and Principles of Palliative Radiation by Body Site or Special Population 12 Palliative Radiotherapy in the Head and Neck 13 Palliative Thoracic Radiation 14 Palliative Radiotherapy in the Breast and Chest Wall 15 Palliative Radiotherapy for Gastrointestinal Malignancies 16 Palliative Radiotherapy for Gynecologic Malignancies 17 Palliative Radiotherapy in Pediatrics 18 Radiotherapeutic Palliation of Lymphoma 19 Radiotherapeutic Palliation of Bone Marrow Diseases-Leukemia and Multiple Myeloma 20 Palliative Radiotherapy in Bones 21 Palliative Radiotherapy in the Brain 22 Palliative Radiotherapy in the Spine 23 Palliative Radiotherapy in Oligometastases 24 Palliative Radiotherapy in the Older Adult SECTION IV Management of Symptoms and Treatment- Related Toxicities 25 General Symptom Overview: Importance of Side Effect Management, CINV, Anorexia, and Cachexia 26 Management of Pain 27 Management of Fatigue 28 Management of Skin Toxicity 29 Central Nervous System: Symptoms and Toxicities 30 Management of Symptoms and Treatment-Related Toxicities of Head and Neck Cancers 31 Chest and Thorax: Symptoms and Toxicities 32 Abdomen and Pelvis: Symptoms and Toxicities 33 Late Toxicities Management 34 Psychosocial and Spiritual Distress Index

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Book SynopsisTable of ContentsTentative TOC: Introduction: Chapter 1.0 Development and Structure of the Lymphoid System embryologic development gross anatomy of the human immune system lymphatic endothelial cells, heterogeneity of, and lymph node microscopic structure lymph node function; afferent lymph cellular components role of the gut microbiome in immune system development specific functions related to the spread of cancer cancer-induced lymphangiogeneis; sentinel LNs Chapter 2.0 The Chemistry, Structure, and Function of Immunoglobulins immunoglobulin isotypes the structure of immunoglobulins the genetics of immunoglobulin diversity antibody-dependent cellular cytotoxicity heavy-chain C domain and role of glycosylation the development of humanized monoclonals Chapter 3.0 The Role of the Complement System in Cancer complement system activation pathways (classical, alternative and lectin) the role of complement activation in cancer progression complement regulatory proteins (CRPs) and cancer the role of compliment activation in the tumor microenvironment enhances tumor growth complement-dependent cytotoxicity in immune therapy of cancer formation of the membrane attack complex (MAC) potential application of anti-complement cancer therapies (C3aR/C5aR/IL-10 pathway) Chapter 4.0 Cancer as Non-Self 4.1 primary generator of tumor-specific transplantation type antigens 4.2 character of non-self, tumor associated antigens 4.3 immune surveillance - innate immunity 4.4 distinguishing between self and non-self 4.5 toll-like receptors (TLRs); soluble bioactive proteins such as cytokines and C' proteins 4.6 NK cells Chapter 5.0 The Adaptive Immune Response in Cancer the diversity of active tumor antigen receptors target specificity without limits in cancer-receptor variability tumor antigen presentation; dendritic cells immune response stimulation against the cancer Cytotoxic T-cells and T-regulatory cells B-cells and antibodies Chapter 6.0 The Science of Innate Immunity 6.1 critical regulator of human inflammatory disease 6.2 anatomic and physiologic barriers to pathogens - cancer causing viruses 6.3 centrally a limited number of critical receptors 6.4 the character of the inflammatory response 6.5 lack of ability to form memory 6.5 role in activating subsequent adaptive immune response Chapter 7.0 Immune Surveillance 7.1 history of concept (Ilya Mechnikov 1908 Nobel Prize) 7.2 evidence for immune surveillance today 7.3 cancer in the immunocompromised host Chapter 8.0 Cancer - Avoiding Immune Detection 8.1 cancer and the presence of immune resistance 8.2 concept for the development of tumor cell tolerance Chapter 9.0 Active Immunization Against Cancer and Cell-based Therapies 9.1 infusing in-vitro expanded Tumor Infiltrating Lymphocytes (TILs) 9.2 infusing dendritic cells pre-loaded with tumor specific oligopeptide antigens 9.3 B7 co-activating receptor 9.4 vaccines Chapter 10.0 The Three Major Clinical Components of Cancer Immunotherapy (modulating cell-mediated immune mechanisms) 10.1 the role of and application of check point blockade 10.2 the role and application of cell-based therapies including CAR-T cell therapies 10.3 antibodies (and vaccines); monoclonal antibodies and novel application of bi- or tri-specifics Chapter 11.0 The Clinical Application of Immunotherapeutics 11.1 in melanoma cancer 11.2 in breast cancer 11.3 in pancreatic cancer 11.4 in colon and rectum cancer 11.5 in prostate cancer 11.6 in leukemias and hematologic malignancies 11.7 in other malignancies Chapter 12.0 Cancer Immunotherapy in the Presence of COVID-19 12.1 immune response to coronavirus-2 infection 12.2 CD8+ T cell depression during chronic viral infection and cancer 12.3 checkpoint inhibitors in cancer patients with coronavirus infection 12.4 coronavirus depletion of CD4+ T cells

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