Medical research Books
Nova Science Publishers Inc Leading Edge Antioxidants Research
Book SynopsisIn biological systems, the normal processes of oxidation (plus a minor contribution from ionising radiation) produce highly reactive free radicals. These can readily react with and damage other molecules. In some cases the body uses free radicals to destroy foreign or unwanted objects, such as in an infection. However, in the wrong place, the body''s own cells may become damaged. Should the damage occur to DNA, the result could be cancer. Antioxidants decrease the damage done to cells by reducing oxidants before they can damage the cell. Virtually all studies of mammals have concluded that a restricted calorie diet extends the lifespan of mammals by as much as 100%. This remarkable finding suggests that food is actually more damaging than smoking. As food produces free radicals (oxidants) when metabolised, antioxidant-rich diets are thought to stave off the effects of ageing significantly better than diets lacking in antioxidants. The reduced levels of free radicals, resulting from a reduction in their production by metabolism, is thought to be a major cause of the success of caloric restriction in increasing life span. Antioxidants consist of a group of vitamins including vitamin C, vitamin E, selenium and carotenoids (such as beta-carotene, lycopene, and lutein). This new book brings together the latest research in this dynamic field.
£176.24
Nova Science Publishers Inc New Research on Fragile X Syndrome
Book SynopsisFragile X syndrome (FXS), is the most common cause of inherited mental impairment. This impairment can range from learning disabilities to more severe cognitive or intellectual disabilities (sometimes referred to as mental retardation). FXS is the most common known cause of autism or ''autistic-like'' behaviour. Symptoms also can include characteristic physical and behavioural features and delays in speech and language development. This new book presents the latest research in this field.
£176.24
Nova Science Publishers Inc New Developments in Stroke Research
Book SynopsisA stroke occurs when the blood supply to the part of the brain is suddenly interrupted (ischemic) or when a blood vessel in the brain bursts, spilling blood into the spaces surrounding the brain cells (haemorrhagic). Generally, there are three treatment stages for stroke: prevention, therapy immediately after stroke, and post-stroke rehabilitation. Therapies to prevent stroke are based on treating an individual''s underlying risk factors. This book includes within its scope the prevention, risk factors, symptoms, diagnosis, treatment, and rehabilitation of stroke. Leading-edge scientific research from throughout the world is presented.
£176.24
Nova Science Publishers Inc Thrombohemostatic Disease Research
Book SynopsisThrombohemostatic disorder is a common haematological problem. This book focuses on the "thrombohemostatic disorder" in several aspects including summative data from the molecular to the population scales, as well as additional metanalysis for important topics.
£176.24
Nova Science Publishers Inc New Developments in Birth Defects Research
Book SynopsisBirth defects are defined as abnormalities of structure, function, or body metabolism that are present at birth. These abnormalities lead to mental or physical disabilities or are fatal. There are over 4,000 different known birth defects ranging from minor to serious, and although many of them can be treated or cured, they are the leading cause of death in the first year of life. This book presents leading research in this field from around the world.
£176.24
Nova Science Publishers Inc New Research on Cutaneous Lymphomas
Book SynopsisCutaneous lymphoid infiltrates which are suspicious for lymphoma, are always important challenges for the general pathologist who faces them occasionally. Many times they are also difficult even for the dermatopathologist, and the most modern diagnostic weapons sometimes play a crucial role in the differential diagnosis with other non-malignant entities, as well as between the different types of lymphomas. Clinically, they sometimes simulate many other conditions, and are not always easy to be recognise by the dermatologist. In 2005, a new classification of cutaneous lymphomas was published, in an attempt to achieve a better comprehension of the nature and behaviour of these tumours. Nevertheless, many new aspects of pathogenesis, diagnosis and differential diagnosis, are constantly appearing in medical literature. This current book is an attempt to present to the reader, the field of cutaneous lymphomas in a way that can be useful in daily practice, either as a general surgical pathologist, a dermatologist, or a dermatopathologist. At the same time, the reader will find updated information which will probably be very helpful in order to face confidently most of the difficult clinical and histopathologic cases. The book goes through most of the cutaneous lymphomas in systematic order, either B-cell, T-cell, or Hodgkin type, presenting the clinical, and morphological aspects, which include many of the most recent molecular contributions. Many of the chapters also provide a therapeutic approach.
£999.99
Nova Science Publishers Inc Focus on Cell Apoptosis Research
Book SynopsisApoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer''s disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. The aim of this book is to provide untouched studies in this new and exciting field.
£176.24
Nova Science Publishers Inc Smoking & Health: Research Frontiers
Book SynopsisSmoking is a greater cause of death and disability than any single disease, says the World Health Organisation. According to their figures, it is responsible for approximately five million deaths world-wide every year. Tobacco smoking is a known or probable cause of approximately 25 diseases including cancer, heart attacks and strokes. The WHO says that its impact on world health is still not fully assessed. This book offers leading edge research from around the globe with a focus on smoking cessation and the effects of passive smoking on health.
£176.24
Nova Science Publishers Inc Focus on Neuroblastoma Research
Book SynopsisNeuroblastoma is a cancer that develops from nerve cells found in several areas of the body. Neuroblastoma most commonly affects children age 5 or younger, though it may rarely occur in older children and adults. Neuroblastoma is the most common cancer in babies. Neuroblastoma develops in tissue that makes up the sympathetic nervous system -- the system of nerves that automatically regulates your heart rate, blood pressure and digestion. Neuroblastoma most commonly arises in and around the adrenal glands, which sit atop the kidneys. However, Neuroblastoma can also develop in other areas of the abdomen and in the chest, neck and pelvis. This book presents important research in this field of research.
£176.24
Nova Science Publishers Inc New Research on Precancerous Conditions
Book SynopsisThis book presents new and important research on precancerous conditions. A precancerous condition is a disease, syndrome, or finding that, if left untreated, may lead to cancer. These include: Cervix Dysplasia; Erythroplasia; Leukoplakia; Lymphomatoid Granulomatosis; Lymphomatoid Papulosis; Preleukemia; Xeroderma Pigmentosum. The identification and treatment of precancerous conditions on a wide-scale could lead to significant drops in deaths due to cancer.
£176.24
Nova Science Publishers Inc Cellular Signaling & Apoptosis Research
Book SynopsisApoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer''s disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book focuses on cell apoptotic signalling.
£176.24
Nova Science Publishers Inc Cognitive Disorders Research Trends
Book SynopsisCognitive disorders are disturbances in the mental process related to thinking, reasoning, and judgement. They include delirium, dementia, and other cognitive disorders. Cognition includes the domains of attention, memory, language, gnosis, visuo-spatial function, praxis, and executive function, and is traditionally distinguished from the emotions or ''feelings''. Cognitive disorders may disturb one domain specifically, as in a selective impairment of memory (amnesia) or language (aphasia), or, more often, a combination of deficits, as in mental retardation and dementia.
£176.24
Nova Science Publishers Inc Transplantation Immunology Research Trends
Book SynopsisIn recent years, transplantation immunology has evolved as a distinct field founded on the recognition that rejection of a transplanted organ or tissue is mediated by immune mechanisms in the host responding to antigens in the donor tissue. Included within the scope are T cell immunity; Antigen presentation; Alloreactivity; Pancreas and islet cell transplantation; Allogeneic bone marrow transplantation Models of tolerance induction; Xenotransplantation and The swine leukocyte antigen (SLA) complex. This book gathers the latest research in the exciting new field of transplantation immunology.
£176.24
Nova Science Publishers Inc Malaria Research Trends
Book SynopsisMalaria is an infectious disease that is widespread in tropical and subtropical regions. It infects between 300 and 500 million people every year and causes between one and three million deaths annually, mostly among young children in Sub-Saharan Africa. Malaria is not just a disease commonly associated with poverty, but is also a cause of poverty and a major hindrance to economic development. Malaria is one of the most common infectious diseases and an enormous public-health problem. Malaria is one of the most common infectious diseases and an enormous public-health problem. The disease is caused by protozoan parasites of the genus Plasmodium. The most serious forms of the disease are caused by Plasmodium falciparum and Plasmodium vivax, but other related species (Plasmodium ovale and Plasmodium malariae) can also infect humans. This group of human-pathogenic Plasmodium species are usually referred to as malaria parasites. Malaria parasites are transmitted by female Anopheles mosquitoes. The parasites multiply within red blood cells, causing symptoms that include fever, anaemia, chills, flu-like illness, and in severe cases, coma and death. Malaria transmission can be reduced by preventing mosquito bites with mosquito nets and insect repellents, or by mosquito control by spraying insecticides inside houses and draining standing water where mosquitoes lay their eggs. One of the most important recent advances in malaria research is the mapping of the Plasmodium falciparum genome. For the next five to ten years, until an effective vaccine is developed, malaria control will largely be dependent on vector control measures such as improvements in housing construction, source reduction, impregnated bednets, and residual insecticide treatment. This book presents leading-edge research in this field.
£176.24
Nova Science Publishers Inc New Developments in Metastasis Suppressor
Book SynopsisThe spread of cancer cells from their organ of origin to distant tissues is called metastasis. Cancer metastasis is the main cause of death from cancer, and in many cases is difficult to detect or treat. The process by which tumour cells become metastatic is complex and involves many stages, including detachment of cells from the main tumour mass, degradation of the surrounding extra-cellular matrix, invasion into nearby blood vessels, travel and survival through the circulatory system, attachment to a vessel wall, extra-vasation, degradation of the extra-cellular matrix into a distant tissue/organ, and the development of a novel blood supply. In order to accomplish this process, the cells acquire characteristics which are important for each stage. Recently, a class of genes known as metastasis suppressors'' has been the subject of intense investigation. For some metastasis suppressor genes, there is strong evidence from both in vitro and in vivo studies to demonstrate key roles in the metastatic process, for others data is much more limited, and their importance uncertain. In this book, chapters are devoted to providing up-to-date summaries of our understanding of individual metastasis suppressor genes. Each is written by a leading authority in the study of that gene. Topics covered include discussions on how each metastasis suppressor was discovered, the mechanisms underlying their loss of expression in tumours and tumour cell lines, their proposed molecular functions, and the consequences to a tumour cell of the loss of this function. This compilation aims to provide, in a single volume, comprehensive information that will be valuable to all scientists working in cancer research, to students needing to understand molecular events that regulate tumour progression and the acquisition of metastasis, and to clinicians who might wish to know more of the roles of potentially new markers for cancer diagnosis and prognosis.
£129.74
Nova Science Publishers Inc Stem Cell: Research Trends
Book SynopsisAmong the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson''s disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson''s disease, and Alzheimer''s disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book presents important research from around the globe.
£176.24
Nova Science Publishers Inc Progress in Cancer Research
Book SynopsisCancer is a group of different diseases (more than 100) characterised by uncontrolled growth and spread of abnormal cells. Cancer can arise in many sites and behave differently depending on its organ of origin. If a cancer spreads (metastasises), the new tumour bears the same name as the original (primary) tumour. Significant progress has been made in recent years in the battle against cancer and in understanding its underlying biological mechanisms. This research progress has resulted in many experimental treatments and cures which establish hope for wide-spread cures. This book presents leading-edge research from around the world.
£176.24
Nova Science Publishers Inc Progress in Sleep Apnea Research
Book SynopsisSleep apnea or sleep apnoea is a sleep disorder characterised by pauses in breathing during sleep. These episodes, called apneas (literally, "without breath"), each last long enough so one or more breaths are missed, and occur repeatedly throughout sleep. There are two distinct forms of sleep apnea: Central and Obstructive. Breathing is interrupted by the lack of effort in Central Sleep Apnea, but from a physical block to airflow despite effort in Obstructive Sleep Apnea. In Mixed Sleep Apnea, both types of events occur. Regardless of type, the individual affected with sleep apnea is rarely (if ever) aware of having difficulty breathing, even upon awakening. Sleep apnea is recognised as a problem by others witnessing the individual during episodes, or is suspected because of its effects on the body (sequelae). This volume examines leading-edge research important for an understanding of the field.
£176.24
Nova Science Publishers Inc New Sleep Apnea Research
Book SynopsisSleep apnea or sleep apnoea is a sleep disorder characterised by pauses in breathing during sleep. These episodes, called apneas (literally, "without breath"), each last long enough so one or more breaths are missed, and occur repeatedly throughout sleep. There are two distinct forms of sleep apnea: Central and Obstructive. Breathing is interrupted by the lack of effort in Central Sleep Apnea, but from a physical block to airflow despite effort in Obstructive Sleep Apnea. In Mixed Sleep Apnea, both types of events occur. Regardless of type, the individual affected with sleep apnea is rarely (if ever) aware of having difficulty breathing, even upon awakening. Sleep apnea is recognised as a problem by others witnessing the individual during episodes, or is suspected because of its effects on the body. This volume offers new and valuable research developments.
£176.24
Nova Science Publishers Inc Dendrimers in Medicine
Book SynopsisThe dendrimer is a common name of polymers which are characterised by a specific structure, although their chemical composition can be very different. Dendrimers display several characteristics which distinguish them from linear polymers. All dendrimers are synthesised by attaching branched monomers to the central core molecule. Monomers are attached layer by layer. As a result of such a synthesis, dendrimers posses plenty of terminal, reactive groups on their surface and empty internal cavities. Both of these features can be utilised. Soon after the first synthesis in mid-1980''s, dendrimers have become interesting and promising molecules for pharmaceutical and technical aims. The last years brought many new facts about dendrimers impact on biological systems. Both, general toxic studies, as well as detailed research devoted to particular cellular compounds, as DNA or lipid bilayer, were carried out. New types of dendrimers were synthesised and new applications appeared.
£176.24
Nova Science Publishers Inc Frontiers in Breast Cancer Research
Book SynopsisBreast cancer is a malignant tumour that has developed from cells of the breast. A malignant tumour is a group of cancer cells that may invade surrounding tissues or spread (metastasize) to distant areas of the body. The disease occurs almost entirely in women, but men can get it as well. The main types of breast cancer are ductal carcinoma in situ, invasive ductal carcinoma, lobular carcinoma in situ, invasive lobular carcinoma, medullary carcinoma, and Paget''s disease of the nipple . About 1 of 8 women will get it in her lifetime. This book presents the latest research in this field.
£149.99
Nova Science Publishers Inc Progress in DNA Methylation Research
Book SynopsisDNA methylation is a type of chemical modification of DNA that can be inherited without changing the DNA sequence. As such, it is part of the epigenetic code and is the most characterised epigenetic mechanism. DNA methylation involves the addition of a methyl group to DNA -- for example, to the number 5 carbon of the cytosine pyrimidine ring. DNA methylation is probably universal in eukaryotes. In humans, approximately 1% of DNA bases undergo DNA methylation. In adult somatic tissues, DNA methylation typically occurs in a CpG dinucleotide context; non-CpG methylation is prevalent in embryonic stem cells.In plants, cytosines are methylated both symmetrically (CpG or CpNpG) and asymmetrically (CpNpNp), where N can be any nucleotide. The methylation status of specific cytosines can be determined using methods based on bisulfite sequencing. This book presents leading-edge research advances in the field.
£999.99
Nova Science Publishers Inc Cardiac Arrythmia Research Advances
Book SynopsisCardiac arrhythmia is a term that denotes a disturbance of the heart rhythm. Cardiac arrhythmias can range in severity from entirely benign to immediately life-threatening. A cardiac arrhythmia, also called cardiac dysrhythmia, is a disturbance in the regular rhythm of the heartbeat. Several forms of cardiac arrhythmia are life-threatening and a medical emergency. Cardiac arrhythmias sometimes are classified according to their origin as either ventricular arrhythmias (originating in the ventricles) or supraventricular arrhythmias (originating in heart areas above the ventricles, typically the atria). They also can be classified according to their effect on the heart rate, with bradycardia indicating a heart rate of less than 60 beats per minute and tachycardia indicating a heart rate of more than 100 beats per minute. This book presents new and important research in the field including an Expert Commentary on collateral damage.
£999.99
Nova Science Publishers Inc Tumorigenesis Research Advances
Book SynopsisTumourigenesis is the formation of tumours in the body, often caused by oncogenes. These tumours are the result of uncontrollable reproduction (cell division) due to alterations in the cell''s genetic code, creating lesions in the tissue where they reside. Tumourigenesis can be divided into tumour initiation, promotion and progression. Oncogenomics often studies tumours caused by such a condition in hope of pinpointing genes -- pieces of genetic information -- that are susceptible to being changed (mutated) by external factors like ultraviolet light, toxic chemicals, and other carcinogens. The range of normal genetic alterations that a person''s DNA undergoes over time is extraordinarily large, so it is hard to detect exactly what cause tumourigenesis. This book presents the latest research advances in the field.
£149.99
Nova Science Publishers Inc Progress in Cancer Drug Resistance Research
Book SynopsisOne of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells. The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100% effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumours, even those from the same tissue of origin. Frequently resistance is intrinsic to the cancer, but as therapy becomes more and more effective, acquired resistance has also become common. The most common reason for acquisition of resistance to a broad range of anticancer drugs is expression of one or more energy-dependent transporters that detect and eject anti-cancer drugs from cells, but other mechanisms of resistance including insensitivity to drug-induced apoptosis and induction of drug-detoxifying mechanisms probably play an important role in acquired anticancer drug resistance. Studies on mechanisms of cancer drug resistance have yielded important information on how to circumvent this resistance to improve cancer chemotherapy and have implications for pharmacokinetics of many commonly used drugs.
£999.99
Nova Science Publishers Inc Progress in Systemic Lupus Erythematosus Research
Book SynopsisThis new book is devoted to leading-edge research developments in lupus which is a condition of chronic inflammation caused by an autoimmune disease. Autoimmune diseases are illnesses that occur when the body''s tissues are attacked by its own immune system. The immune system is a complex system within the body that is designed to fight infectious agents, for example, bacteria, and other foreign invaders. One of the mechanisms that the immune system uses to fight infections is the production of antibodies. Patients with lupus produce abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents. Because the antibodies and accompanying cells of inflammation can involve tissues anywhere in the body, lupus has the potential to affect a variety of areas of the body. Sometimes lupus can cause disease of the skin, heart, lungs, kidneys, joints, and/or nervous system. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus (SLE).
£149.99
Nova Science Publishers Inc Progress in Circadian Rhythm Research
Book SynopsisA circadian rhythm is a roughly-24-hour cycle in the physiological processes of living beings, including plants, animals, fungi and cyanobacteria. The term ''circadian'', comes from the Latin circa, ''around'', and dies, ''day'', meaning literally ''about a day''. The formal study of biological temporal rhythms such as daily, weekly, seasonal, and annual rhythms, is called chronobiology. In a strict sense, circadian rhythms are endogenously generated, although they can be modulated by external cues such as sunlight and temperature. Most of a person''s body systems demonstrate circadian variations. The body systems with the most prominent circadian variations are the sleep-wake cycle, the temperature regulation system, and the endocrine system. The malfunctioning of a person''s circadian system, or biological clock, causes circadian rhythm disorders. Circadian rhythms and their relation to health outcomes in the globalised hyper world of the 21st century are now understood to be extremely important.
£149.99
Nova Science Publishers Inc Sympathetic Nervous System Research Developments
Book SynopsisThis book presents the latest research on the sympathetic nervous system (SNS) which is a branch of the autonomic nervous system. It is always active at a basal level (called sympathetic tone) and becomes more active during times of stress. Its actions during the stress response comprise the fight-or-flight response. Like other parts of the nervous system, the sympathetic nervous system operates through a series of interconnected neurons. Sympathetic neurons are frequently considered part of the peripheral nervous system (PNS), although there are many that lie within the central nervous system (CNS). Sympathetic neurons of the spinal cord (which is part of the CNS) communicate with peripheral sympathetic neurons via a series of sympathetic ganglia. Within the ganglia, spinal cord sympathetic neurons join peripheral sympathetic neurons through chemical synapses. Spinal cord sympathetic neurons are therefore called presynaptic (or preganglionic) neurons, while peripheral sympathetic neurons are called postsynaptic (or postganglionic) neurons. At synapses within the sympathetic ganglia, preganglionic sympathetic neurons release acetylcholine, a chemical messenger that binds and activates nicotinic acetylcholine receptors on postganglionic neurons. In response to this stimulus, postganglionic neurons principally release noradrenaline (norepinephrine). Prolonged activation can elicit the release of adrenaline from the adrenal medulla. Once released, noradrenaline and adrenaline bind adrenergic receptors on peripheral tissues. Binding to adrenergic receptors causes the effects seen during the fight-or-flight response. These include pupil dilation, increased sweating, increased heart rate, and increased blood pressure.
£149.99
Nova Science Publishers Inc Oxidative Stress: Clinical & Biomedical
Book Synopsis
£129.74
Nova Science Publishers Inc Research Progress in Alzheimer's Disease &
Book SynopsisAlzheimer''s disease (AD), the most common form of neurodegenerative disorder in the elderly, is characterised pathologically by extracellular amyloid plaques and intracellular neurofibrillary tangles, pathophysiologically by synaptic dysfunction, and clinically by a progressive decline in cognition. Currently, AD has no cure and its prevalence is predicted to triple by 2050 with the rapid increase in the ageing population, unless more effective treatments are developed. Since the publication of the second book volume, the rapid progress in the research fields of AD and dementia continues through the intensive efforts of research scientists worldwide. This third book volume contains 15 chapters, bringing together a presentation of research frontiers in current AD/dementia research. The topics include molecular genetics of AD, gene expression abnormalities in AD progression, presenilins, taupathy in AD, single -induced(neuron gene expression abnormalities in AD, intracellular A neurodegeneration, roles of lipoprotein receptors in AD onset and progression, cholesterol and tau hyperphosphorylation, AD diagnostics and therapeutic strategies, in vivo visualisation of amyloid-like structures, cathepsin B, antiamyloidogenesis and neuroprotection, environmental enrichment, Fragile X mental retardation gene and dementia, category learning in Parkinson''s disease, cerebrovascular disease and dementia, and dementia and hypertension. These chapters cover current advances in our understanding of the pathogenic mechanisms underlying AD and dementia, in the diagnosis of early AD and dementia, and in the development of therapeutic agents that target memory-relevant AD pathogenesis. The book will be highly valuable to students and scientists worldwide who are interested in the scientific research progress in AD and dementia.
£999.99
Nova Science Publishers Inc New Gene Therapy & Cancer Research
Book SynopsisGenes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it''s the proteins that perform most life functions and even make up the majority of cellular structures. When genes are altered so that the encoded proteins are unable to carry out their normal functions, genetic disorders can result. Gene therapy is an experimental treatment that involves introducing genetic material into a person''s cells to fight disease. Gene therapy is being studied in clinical trials for many different types of cancer and for numerous other diseases. This book offers important research from around the globe dedicated to this dynamic subject.
£149.99
Nova Science Publishers Inc Cancer Research Perspectives
Book SynopsisCancer is a group of different diseases (more than 100) characterised by uncontrolled growth and spread of abnormal cells. Cancer can arise in many sites and behave differently depending on its organ of origin. If a cancer spreads (metastases), the new tumour bears the same name as the original (primary) tumour. Significant progress has been made in recent years in the battle against cancer and in understanding its underlying biological mechanisms. This research progress has resulted in many experimental treatments and cures which establish hope for wide-spread cures. This book presents new research of importance to the field.
£149.99
Nova Science Publishers Inc Coumarin Anticoagulant Research Progress
Book SynopsisWarfarin (also known under the brand names of Coumadin, Jantoven, Marevan, and Waran) is an anticoagulant medication that is administered orally or, very rarely, by injection. It is used for the prophylaxis of thrombosis and embolism in many disorders. Its activity has to be monitored by frequent blood testing for the international normalised ratio (INR). It is named for the Wisconsin Alumni Research Foundation. Warfarin is a synthetic derivative of coumarin, a chemical found naturally in many plants, notably woodruff (Galium odoratum, Rubiaceae), and at lower levels in liquorice, lavender and various other species. Warfarin was originally developed as a rat poison; however, more modern poisons are much more potent and toxic (e.g., brodifacoum). Warfarin and contemporary rodenticides belong to the same class of drugs (coumarins) and both decrease blood coagulation by interfering with vitamin K metabolism. For this reason, drugs in this class are also referred to as vitamin K antagonists.
£999.99
Nova Science Publishers Inc Progress in Stem Cell Research
Book SynopsisAmong the many applications of stem cell research are nervous system diseases, diabetes, heart disease, autoimmune diseases as well as Parkinson''s disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson''s disease, and Alzheimer''s disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This new book presents the latest research from around the globe.
£999.99
Nova Science Publishers Inc Bird Flu: The New Emerging Infectious Disease
Book SynopsisThis book focuses on the "Bird Flu: the new emerging infectious disease", a new health problem, and the aspects relating to the use of tropical medicine. It specifically covers the clinical aspects, scientific laboratory, public health, as well as the social sciences relating to this new important infectious disease. Mainly, the book presents summative data from the molecular to the population scales, as well as additional metanalysis for important topics. In addition, the diagnostic guideline and clinical practice guidelines of the mentioned conditions are detailed. There is still limited knowledge on this topic while the wider distribution of the disorder due to the globalisation can be expected.
£149.99
Nova Science Publishers Inc Tissue Engineering: Roles, Materials &
Book SynopsisTissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physio-chemical factors to improve or replace biological functions. While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, etc.). Often, the tissues involved require certain mechanical and structural properties for proper function. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bioartificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells to produce tissues. This book presents recent and important research in the field.
£999.99
Nova Science Publishers Inc Developments in Stem Cell Research
Book Synopsis
£999.99
Nova Science Publishers Inc Caffeine & Health Research
Book SynopsisCaffeine is the most widely consumed drug in the world, most commonly from the beverages coffee, tea and soda. An estimated 80% of the world''s population consumes a caffeine-containing substance daily. A typical 8-ounce (240-ml) cup of instant coffee contains about 100 mg of caffeine - about twice as much as a cup of tea or a 12-ounce (360-ml) can/bottle of soda. A 30-gram chocolate bar might contain as much caffeine as half a cup of tea. More than 99% of orally ingested caffeine is absorbed -- with peak plasma levels obtained in 15 to 45 minutes. Caffeine is soluble in both water and oil and can readily cross the blood-brain barrier. Caffeine potentially has pharmacological actions other than blockage of adenosine receptors, but it requires 20 times as much caffeine to inhibit phosphodiesterase, 40 times as much caffeine to block GABAA receptors and 100 times as much caffeine to mobilise intracellular calcium as is required to block adenosine receptors. Caffeine acts primarily by the direct action of blocking adenosine receptors and by the indirect action upon the receptors for neurotransmitters. This book presents important research on this fascinating and relevant field of research.
£999.99
Nova Science Publishers Inc Stem Cells & Regenerative Medicine: Volume I:
Book SynopsisThe subject of this book is stem cell research and regenerative medicine. Stem cells are undifferentiated cells that have the ability to differentiate into different lineages of the body. Stem cells carry tremendous potential for the treatment of a broad range of disease and injuries. Stem cells exist in embryonic, fetal, and adult tissues, including the adult central nervous system. This book aims at, in depth, the recent developments in stem cell research and regenerative medicine. Though this book encompasses all the fields of stem cell research and regenerative medicine, it emphasises adult neurogenesis and neural stem cell research and therapy.
£73.49
Nova Science Publishers Inc Stem Cells & Regenerative Medicine: Volume II:
Book SynopsisThe subject of this book is stem cell research and regenerative medicine. Stem cells are undifferentiated cells that have the ability to differentiate into different lineages of the body. Stem cells carry tremendous potential for the treatment of a broad range of disease and injuries. Stem cells exist in embryonic, foetal, and adult tissues, including the adult central nervous system. This book aims at, in depth, the recent developments in stem cell research and regenerative medicine. Though this book encompasses all the fields of stem cell research and regenerative medicine, it emphasises embryonic and adult stem cells.
£73.49
Nova Science Publishers Inc Stem Cells & Regenerative Medicine: Volume III:
Book SynopsisThe subject of this book is stem cell research and regenerative medicine. Stem cells are undifferentiated cells that have the ability to differentiate into different lineages of the body. Stem cells carry tremendous potential for the treatment of a broad range of disease and injuries. Stem cells exist in embryonic, foetal, and adult tissues, including the adult central nervous system. This book aims at, in depth, the recent developments in stem cell research and regenerative medicine. Though this book encompasses all the fields of stem cell research and regenerative medicine, it emphasises adult neurogenesis and neural stem cell research and therapy within the context of pharmacology and therapy.
£999.99
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 5
Book Synopsis"Advances in Medicine and Biology" presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum. This book presents and discusses topical data including: the use of complementary and alternative medicine among Chinese Canadians; evidence-based diagnostic test interpretation; angiotensin converting enzyme inhibitors for use as antihypertensive agents; membrane protein structure in the vitamin K cycle; the diagnostic value of the visual-vestibular interaction test with rotary chamber in the diagnosis of vertigo; the role of hair in the biological evolution of humans; and others.
£176.24
Nova Science Publishers Inc Stem Cells Research Compendium: Volume 2
Book SynopsisThe two broad categories of mammalian stem cells exist: embryonic stem cells, derived from blastocysts, and adult stem cells, which are found in adult tissues. In a developing embryo, stem cells are able to differentiate into all of the specialised embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialised cells. As stem cells can be readily grown and transformed into specialised tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed. In particular, embryonic cell lines, autologous embryonic stem cells generated therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates. Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson''s disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, and Alzheimer''s disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This new Book presents leading research from around the world in this field which is of interest to so many and presents so many hopes.
£113.24
Nova Science Publishers Inc Stem Cells
Book SynopsisStem cells are the building blocks of the body. They can develop into any of the cell types that make up our bodies. During development, they contribute to the formation of the tissues. In the adult, they contribute to homeostasis of the tissues and regeneration after injury. Stem cells carry a lot of hope for the treatment of a broad range of diseases and injuries, spanning from neurological diseases and injuries, like Alzheimer''s disease, Parkinson''s disease and spinal cord injuries, to diabetes, genetic diseases, graft-versus-host diseases, eye, heart and liver diseases, inflammatory and autoimmune disorders, and cancers. Stem cell research is therefore as important for our understanding of development, physio- and pathology of the body, as for therapy. ''Stem Cells'' aims at providing an overview and in depth analysis of recent developments in stem cell research and therapy. It is composed of recently published review articles that encompass the field of stem cell research and regenerative medicine. All the articles went through peer-review process.
£73.49
Nova Science Publishers Inc Pioneering Human Myoblast Genome Therapy
Book SynopsisHuman Myoblast Genome Therapy (HMGT) is a platform technology of cell transplantation, nuclear transfer, and tissue engineering. Myoblasts are differentiated, immature cells destined to become muscles. Myoblasts cultured from muscle biopsy survive, develop and function to revitalise degenerative muscles upon transplantation. Transplant injury activates regeneration of host myofibers that fuse with the injected myoblasts, sharing their nuclei in a common gene pool of the syncytium. Thus, through nuclear transfer and complementation, human genome can be transferred into muscles of genetically-ill patients to achieve phenotype repair. Myoblasts are safe and efficient universal gene transfer vehicles endogenous to muscles that constitute 50% of the body. Myoblasts fuse among themselves to form new myofibres. Patients take only 2-month cyclosporine to immunosuppress allograft rejection because myofibres do not express MHC-1 antigens. The first correction of human gene defect was published in the Lancet on July 14, 1990 when the therapeutic protein dystrophin was found in the myoblast-injected muscle of a Duchenne muscular dystrophy (DMD) patient. Results over 280 HMGT procedures on MD subjects in the past 15 years demonstrated absolute safety. Myoblast-injected DMD muscles showed improved histology. Strength increase at 18 months post-operatively averaged 123%. FDA-approved clinical trials progressed unto Phase III in USA with direct cost recovery. Heart muscle degeneration is the leading cause of human debilitation and death.
£42.39
Nova Science Publishers Inc Advances in Membrane Science & Technology
Book SynopsisIn recent years, membranes and related technologies have gained more technical and commercial relevance. Their applications have extended to environmental, chemical, medical, food, and energy industries. To date, many books on membranes have been published to awaken reader''s interest in this field. This book, however, is intended not to make a summary of the literature in these areas, but to focus on the current status of some advanced membrane technologies which are well related to human life. Eight chapters were contributed by well-known researchers and professors in the corresponding fields. Chapter 1 from Prof. Strathmann takes a roam through membrane science and technology -- from desalination and artificial kidneys to fuel cell separators and membrane reactors, informing the reader of what kind of membrane technologies have come true, or might or might never come true. Chapter 2 by Prof. Tongwen Xu concentrates on the current science and technology using electro-membranes. Chapter 3 treats of the application of membranes to energy supply, which has been a hot issue for sustainable development of our earth and contributed by famous exporter (Dr J Kerres and co-worker). Chapter 4 described novel Inorganic-organic hybrid membranes, which, were recently developed and expected to be applied in such harsh conditions as high temperature and strongly oxidising circumstances. The improvements on traditional chemical processes using membrane technologies are summarised in Chapter 5 by Prof. Chung TS and his co-workers and exemplified with pervaporation for organic separation. Chapter 6 covers a hot issue in our daily life: recycling of municipal waste water using membrane bioreactors and contributed by Prof. Kim In S. Another distinctive characteristic about membrane technologies is integration flexibility, which is crucial to the realisation of multiple functions needed for a specific complex industrial application. Prof. Moon SH and Dr. Lee HJ contributed to such technique integrations. Membrane controlled release, the focus of Chapter 8 from Prof. Chu Ly, is an emerging membrane technology that might come true and has proved important in medical and pharmaceutical applications.
£86.99
Nova Science Publishers Inc Contributions of African American Scientists to
Book SynopsisScientists included in this book represent the fields of biochemistry, biology, chemistry, computer science, dentistry, engineering, entomology, genetics, geology, mathematics, medicine, nursing, physics, psychology, sociology, zoology, and inventions. Described here are African American men and women who have contributed to the advancement of science including inventions. These individuals have contributed in large and small ways that might have been overlooked when chronicling the history of science.
£282.74
Nova Science Publishers Inc Alcohol-Related Cognitive Disorders: Research &
Book SynopsisThis book discusses the different mental and physical aspects of alcohol abuse, including prenatal foetal intoxication. It explores the many types of social behaviour affected by the excessive use of alcohol and the physical repercussions of this syndrome. It covers a vast variety of alcohol related conditions by many select consultants in this field. Alcohol addiction is one of the major disorders encompassing society world round. Its devastating effect on social stability and inter-personal relationships requires aggressive treatment and new ways to evoke the eventual success of sobriety. A book of this magnitude should prove helpful to students, laymen, and professionals in the medical and mental health field.
£86.99
