Medical research Books

Book SynopsisAs a group, carp provide 4 million metric tonnes of fish annually - over a quarter of all fish culture worldwide. For the first time, a book is available in English that concentrates solely on the carp as an economic rather than an ornamental fish with a panel of international experts producing a comprehensive, practical volume about carp production and management. Starting with a brief look at the biology of cyprinids, the book then discusses the methods and management of carp farming, from water quality to the economics of fish production in ponds. Novel methods to improve stock, including genetic engineering, are covered and case studies give added value to the text. As carp farming turns from traditional to intensive methods, farmers, researchers and technicians in industry will welcome this benchmark volume, which also is a valuable reference book for graduate and postgraduate students and lecturers in aquaculture.Table of ContentsBiology of the Cyprinids.- Aquatic Ecosystem and Water Quality.- Reproduction.- Genetic Improvements.- Juvenile Rearing.- Ongrowing in Ponds.- The Creation of Ponds.- Processing and the Markets.- The Economics of Fish Production in Ponds.- Appendices.- Index.

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Book SynopsisThis textbook introduces readers to the scientific basics of cardiovascular medicine and biology. It covers not only developmental but also cellular and molecular aspects of normally functioning vasculature and the heart; importantly, it also addresses the mechanisms leading to and involved in specific cardiovascular diseases. Though the main emphasis is on novel therapies and potential therapeutic targets, specific controversial topics like cardiac remodeling and regenerative capacities are also addressed. All chapters were written by lecturers from the Imperial College London, in collaboration with their students from the College’s BSc Programme in Medical Sciences with Cardiovascular Science. Bridging the gap between clinics and basic biology, the book offers a valuable guide for medical students, and for Master and PhD students in Cardiovascular Biomedicine.Table of Contents- Cardiac Development and Congenital Heart Disease:Cardiac Development Biology – Early Mechanisms Cardiac Development Biology – Late Mechanisms Cardiomyocyte Structure and Function Cardiac Morphology – Anatomy of Congenital Heart Disease Common Congenital Abnormalities - The Science of Arrhythmia: Introduction to the Action Potential Ion transporters and their Properties Excitation Contraction Coupling Tachyarrhythmias Bradyarrhythmias - The Science of Heart Failure: Cardiac Contractility – Normal and Pathological Heart Failure – A Scientific Perspective Cardiomyopathy Therapeutics Novel Therapies - The Science of Vascular Disease: The Vasculature – Pharmacological Targets The Coagulation Cascade and its Therapeutic Modulation Cellular and Molecular Mechanisms of Atherosclerosis Cellular and Molecular Mechanisms of Angiogenesis Endothelial Function and Dysfunction

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Book SynopsisThis volume of the series Springer Briefs in Space Life Sciences explains the physics and biology of radiation in space, defines various forms of cosmic radiation and their dosimetry, and presents a range of exposure scenarios. It also discusses the effects of radiation on human health and describes the molecular mechanisms of heavy charged particles’ deleterious effects in the body. Lastly, it discusses countermeasures and addresses the vital question: Are we ready for launch? Written for researchers in the space life sciences and space biomedicine, and for master’s students in biology, physics, and medicine, the book will also benefit all non-experts endeavouring to understand and enter space.Table of Contents General Introduction: Small Particles, Large Effects (Berger, Baumstark, Hellweg, Matthiä) Radiation in Space – The Physics The Radiation Field in Space (Matthiä, Berger) i. Galactic cosmic rays ii. Solar radiation iii. Trapped radiation iv. Dose quantities The History of Space Radiation Dosimetry (Berger) i. From Mercury to MIR ii. Human Phantom Experiments Exposure Scenarios: Measuring and Modeling of Space Radiation (Berger, Matthiä) i. LEO ii. Interplanetary Space iii. Moon iv. Mars Radiation in Space – The Biology Acute Radiation Effects (Baumstark, Hellweg) Chronic and Late Radiation Effects (Baumstark, Hellweg) Radiation Risk Assessment (Baumstark, Hellweg) Molecular Mechanisms of Heavy Charged Particles Effects (Baumstark, Hellweg) Nutritional and Pharmaceutical Countermeasures (Baumstark, Hellweg) Challenges for Exploratory Missions (Berger, Baumstark, Hellweg, Matthiä) Dosimetry and Shielding: Are we Ready for Launch? Open Questions in Risk Assessment: Can we Tame the Radiation Risk? Countermeasures: Do we Know Enough?

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Book SynopsisThis open access book is the first published guide about how to analyse data produced by the EQ-5D, one of the most widely used Patient Reported Outcomes questionnaires world wide. The authors provide practical, clear and comprehensive guidance in five concise chapters. Following an overview of the EQ-5D and its analysis, we describe how the questionnaire data – the EQ-5D profile and EQ VAS – can be analysed in different ways to generate important insights into peoples’ health. We then show how the value sets which accompany the EQ-5D can be applied to summarise patients’ data. The final chapter deals with advanced topics, including the use of Minimally Important Differences, case-mix adjustment, mapping, and more. This book is essential for those new to analyzing EQ-5D data and will be also be valuable for those with more experience. The methods can be applied to any EQ-5D instrument (for example, the three- and five-level and Youth versions) and many of the methods described will be equally relevant to other Patient Reported Outcomes instruments. Table of ContentsForeword Preface Chapter 1 An introduction to EQ-5D instruments and their applications 1.1 Measuring health using the EQ-5D 1.2 What does the EQ-5D measure? 1.2.1 The EQ-5D self-reported health state (EQ-5D profile) 1.2.2 EQ VAS 1.2.3 EQ-5D values 1.2.4 What aspect of the information provided by the EQ-5D should be the primary focus on my analysis? 1.3 EQ-5D data collection and data handling 1.4 Before starting your analysis 1.4.1Treatment of missing data – what to do, what not to do 1.4.2 Planning your analysis 1.5 Guide to the rest of this book References Chapter 2 Analysis of EQ-5D profile data 2.1 Cross-sectional analysis: describing health at a point in time by dimension and level 2.2 Longitudinal analysis: describing changes in health between two time points by dimension and level 2.3 Cross sectional analysis: describing health at a point in time using profiles 2.4 Longitudinal analysis: describing changes in health between two points in time using profiles 2.4.1 The Paretian Classification of Health Change (PCHC) 2.4.2 The probability of superiority 2.4.3 Health Profile Grid (HPG) 2.5 Summarising the severity of EQ-5D profiles 2.5.1 The level sum score (LSS) 2.5.2 The level frequency score (LFS) 2.6 Analysing the informativity of EQ-5D profile data 2.6.1 Shannon Indices 2.6.2 Health State Density Curve (HSDC) 2.6.3 Health State Density Index (HSDI) and other related indices References Chapter 3 Analysis of EQ VAS data 3.1 Interpreting the EQ VAS 3.2 Simple descriptive statistics and inference 3.3 Modelling determinants of EQ VAS scores References Chapter 4 Analysis of EQ-5D values 4.1 Value sets and their properties 4.2 Positive and normative considerations in choice of value set 4.3 Simple descriptive statistics and inference 4.4 Examining the distribution of EQ-5D values 4.5 Variance and heteroskedasticity 4.6 exploring clusters in EQ-5D value distributions 4.7 Regression analysis 4.8 Uncertainty and sensitivity analysis References Chapter 5 Advanced topics 5.1 Analysing changes and differences in EQ-5D values and EQ VAS scores 5.1.1 Defining the outcomes of an intervention study as a change 5.1.2 Minimal Important Differences (MIDs) · Using EQ-5D MIDs · MID estimation methods 5.1.3 Case-mix and risk adjustment of EQ-5D data 5.2 Mapping References Glossary of terms

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Book SynopsisThis textbook provides step-by-step protocols and detailed explanations for RNA Sequencing, ChIP-Sequencing and Epigenetic Sequencing applications. The reader learns how to perform Next Generation Sequencing data analysis, how to interpret and visualize the data, and acquires knowledge on the statistical background of the used software tools. Written for biomedical scientists and medical students, this textbook enables the end user to perform and comprehend various Next Generation Sequencing applications and their analytics without prior understanding in bioinformatics or computer sciences.Table of Contents

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Book SynopsisThis open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease Table of Contents

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Book SynopsisThis last volume of the SpringerBriefs in Space Life Sciences series is setup in 5 main parts. The 1st part shortly summarizes the history of life science research in space from the late 40s until today with focus on Europe and Germany, followed by a part on describing flight opportunities including the Space Shuttle/Spacelab system and the International Space Station ISS; in the 3rd part it focuses on extraordinary success stories of this constantly challenging research program and highlights some important key findings in space life science research. The book introduces in the 4th part innovative developments in non-invasive biomedical diagnostics and training methods for astronauts that emerge from this program and are of benefit for people on Earth especially in the aging society. Last but not least in its 5th part it closes with an outlook on the future of space life sciences in the upcoming era of space exploration. The book is intended for students and research scientists in the life sciences and biomedicine as well as for interested lay persons, who wish to get an overview of space life science research: its´ early days, current status and future directions.Table of ContentsChapter 1. Introduction: Space Life Sciences – Basic Research and Applications under Extraordinary Conditions.- Chapter 2. A Long Way for Europe and Germany: From Apollo 16 to the International Space Station ISS.- Chapter 3. Success Stories: Incremental Progress and Scientific Breakthroughs in Life Science Research.- Chapter 4. Success Stories: Innovative Developments for Biomedical Diagnostics and Preventative Health Care.- Chapter 5. Space Life Sciences in the Exploration Era: An Outlook on Future Challenges and Opportunities.-

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Book SynopsisThis contributed volume, “Multifaceted Protocols in Biotechnology, Volume 2”, consists of multidisciplinary methods and techniques commonly used in biotechnology studies. There are two sections covered in this book – Ionic Liquid Related Techniques & Evergreen Biotechnology Techniques. A brief introduction supports each protocol to allow easy learning and implementation. The first section consists of three chapters covering studies in modern biotechnology focusing on the role of ionic liquid techniques in extracting secondary metabolites, enzyme stabilization and biomass processing. The second section covers evergreen methodologies. It comprises five chapters covering topics on microcarrier technology for cell culture; Polymerase Chain Reaction for non-halal sources detection in food; ELISA for biomarker identification; gamma ray-induced mutagenesis for enhancing microbial fuel cells; and the effect of temperature on antibacterial activity of Carica papaya seed extract. This book will be useful to graduate students, researchers, academics, and industry practitioners working in the area of biotechnologyTable of ContentsChapter 1Graviola Fruit Extraction by Ionic Liquid Microwave-assisted Extraction (IL-MAE) Daddiouaissa Djabir, and Azura AmidChapter 2Role of Ionic Liquids in the Enzyme Stabilization: A Case Study with Trichoderma ressie Cellulase Amal A. M. Elgharbawy, Md Zahangir Alam, and Muhammad MoniruzzamanChapter 3Role of Ionic Liquids in the Processing of Lignocellulosic BiomassAmal A. M. Elgharbawy, Md Zahangir Alam, Sharifah Shahira Syed Putra and Muhammad MoniruzzamanChapter 4Proliferation of rat amniotic stem cell (AFSC) on modified surface microcarrier.Nurhusna Samsudin, Yumi Zuhanis Has-Yun Hashim, Hamzah Mohd Salleh, and Azmir Ariffin.Chapter 5Application of spectroscopic methods for the analysis of non-halal meats in food products: A narrative reviewAbdul Rohman, Nurrulhidayah Ahmad FadzillahChapter 6Identification of Potential Biomarkers of Porcine GelatinNur Azira Tukiran, Amin Ismail, Haizatul Hadirah Ghazali & Nurul Azarima Mohd AliChapter 7Gamma Ray Mutagenesis on Bacteria Isolated from Shrimp Farm Mud for Microbial Fuel Cell Enhancement and Degradation of Organic WasteAyoub Ahmed Ali, and Azura Amid, Azhar MuhammadChapter 8Effect of temperature on antibacterial activity and fatty acid methyl esters of Carica papaya seed extractMuhamad Shirwan Abdullah Sani, Jamilah Bakar, Russly Abdul Rahman and Faridah AbasChapter 9Solid-state Fermentation of Agro-industrial Waste Using Heterofermentative Lacti Acid Bacteria. Oktaviani, Muhammad Yusuf Abduh, Dea Indriani Astuti, Mia RosmiatiChapter 10Synthesis of chitosan-folic acid nanoparticles as a drug delivery system for propolis compounds Marselina Irasonia Tan and Adelina Khristiani Rahayu

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Book SynopsisThis textbook describes the basic principles and mechanism of action of biosensor systems, and introduces readers to the various types of biosensors; from affinity biosensors to catalytic, optical and label-free biosensors, the most common systems are explained in detail. Dedicated advanced sections focus on biochips and genome sequencing methods as well as organs-on-a-chip. The textbook helps readers to understand the elementary components of biosensors, and to identify and illustrate each function in the biosensor information flow, from recognition to transduction and transmission. Furthermore, readers will receive guidance in critically analyzing published studies on biosensor research, helping them to develop appropriate concepts and independently propose their own solutions. The textbook is intended for master’s students in bioengineering, biophysics, biotechnology and pharmacology that need a solid grasp of biosensor system technologies and applications, as well as students in related medical technological fields.Table of Contents

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Book SynopsisIn the age of "publish or perish," this book provides everything one needs to know about conducting research and successfully publishing it in a scientific journal. The reader learns about the complete process of scientific publishing: from selecting the most appropriate research design, to obtaining permissions and funding, to resourcefully presenting the research results in a poster and oral presentation. Additionally, the practical tips provided here help the reader formulate a compelling scientific article and choose the most suitable journal (subscription vs. the various open access modalities) for their publication.This book also addresses "invisible aspects" of scholarly publishing that are nonetheless important and that everyone should know and understand: avoiding predatory journals, understanding the editor's perspective, and becoming familiar with the various research metrics (from author to journal) that can all determine success or failure of a publication. Written in an informal style in which the author shares personal perspectives and experiences, the book is easily accessible to the reader. The book offers early career scientists in biomedicine and medicine a unique perspective on publishing research articles and how this process can enhance the authors' "scientific value" within the scientific ecosystem as well as their personal CVs.Table of ContentsSee Attachments:

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Book Synopsis.- Cooking, Eating, Tasting..- The Tongue, Chewing and Tasting..- The Five Basic Tastes..- The Nose and Smelling..- Adaptation, Cross-Adaptation and Masking of Odours..- Feeling in the Nose, Mouth and Throat..- Psychology of Tasting and Eating.

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Book SynopsisSustainable Promotion of Mental Health and Prevention of Mental Health Disorders across the World.- Mental Health and Well-being amongst Healthcare Professionals in Clinical Training.- The Role of Mental Health Apps (MHapps) in Furthering Progress on SDG3: A Case for Multi-Stakeholder Collaboration.- Understanding Internet Gaming Disorder in the Technology Era.- Enhancing Life Skills, Self-Esteem, and Lifting of Stigma: How Culture and The Arts Can Contribute to The Well-Being of People with Rare Diseases.- The Role of Green Chemistry in The Management of Self-Harm and Suicides by Hazardous Chemicals.- Mood-Based Prioritization Model in People with Suicidal Tendencies using Topsis.- The Diagnostic, Prognostic and Therapeutic Role of miRNA in the Management of Tropical Diseases.- Old versus New Approaches towards TriTryp Diseases.- Shigellosis: The Road from Multiple Drug-Resistance (MDR) to Vaccine Development.- Effects of Plant Secondary Metabolites on Cardiovascular Diseases Through Non-Coding RNAs.- Global Impact and Strategies to Reduce the Mortality from Cardiovascular Diseases.- Sex-Related Bias in Preclinical Research and its Contribution to Cardiovascular Health Disparities between Women and Men.- Diabetes: A Global Health Concern and Potential Strategies to Reduce Its Prevalence.- Update on Reducing Mortality in Cancer, Case Study Brain.- Disparities and the Hispanic Paradox: Understanding Contributors to Cancer Health Disparities in the U.S. Hispanic Population.- Macroeconomic Needles and Sustainable Development Goal's Number Three in Nigeria.- Ethnomedicine and Non-Communicable Chronic Degenerative Diseases: Local Knowledge and Participation for Wellbeing in Northwest Mexico.- Navigating the New Normal: Exploring the Roadmap for Long-term Care Services in India in the Era of COVID-19.

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Book SynopsisThe Human Intelligence versus Artificial Intelligence: A Controversial Race in Problem-Solving.- Art-Based Continuous Measurement for the Attachment Paradigm: Development and Implementation of a Digital Application.- Does a Financing Scheme Matter for Access to Healthcare Service?.- Integrating Science from the Lab to Population Health.- The Healthy Trinity to Face Non-Communicable Diseases: Physical Activity, Nutrition and Sleep.- Exercise, Hypertension, and Genetics.- Universal Access to Sexual and Reproductive Care.- The Impact of Hazardous Chemicals on Human Health and The Environment: State of the Art and Risk Assessment Tools.- Lessen The Impact of Hazardous Chemicals and Environmental Pollutants on Public Health.- Addressing Hazardous Waste Management as a Means to Achieving the Sustainable Development Goal 3.- Positive Impacts of Air Pollution Reduction on SDG 3 Targets in Urban Environment.- End-To-End Production in Plant Molecular Farming: Integrating Biotechnology and Bioprocess Engineering.- Alcohol and Immunity: Lessons Learned from Fruit Fly Model.- Research Trends Surrounding the Challenges Faced by Health Personnel in Rural Contexts: A Bibliometric Approach.- Strengthening Health Workforce Well-Being: Lessons from the COVID-19 Pandemic.- Unique Strongly Alkaline Electrolyzed Water as a Sustainable Countermeasure against COVID-19 and Future Pandemics.- Viral Infections and Host Immunity: Lessons Learned from Model Organisms.- Supporting Maternal Autonomy in Medical Abortion Pathways.- The Role of Nutrition in Promoting Child and Maternal Health.- Maternal Mortality and Pregnancy Complications: A Current Scenario from Low-Income Countries.- Exploration of HDL-ome during Pregnancy: A Way to Improve Maternal and Child Health.

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Book SynopsisChapter 1 Oxidaitve Stress in Aging.- Chapter 2 Oxidaitve Stress in Inflammation.- Chapter 3 Oxidative Stress in Cardiovascular Diseases.- Chapter 4 Oxidative Stress in Neurodegenerative Diseases.- Chapter 5 Oxidative Stress in Type-2 Diabetes Mellitus.- Chapter 6 Oxidaitve Stress in Infertility.- Chapter 7 Oxidaitve Stress in ß-Thalassemia, Myelodysplastic Syndrome and Acute Leukemia.- Chapter 8 Oxidaitve Stress in Chronic Kidney Disease.- Chapter 9 Oxidaitve Stress in Inflammatory diseases.- Chapter 10 Oxidaitve Stress in Preeclampsia and Preterm Newborn.- Chapter 11 Other Pathologies Related to Oxidative Stress.- Chapter 12 Oxidative Stress-Based Toxicity of Chemical and Physical Agents.- Chapter 13 Antioxidant treatments.- Chapter 14 Antioxidant paradox.

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Book SynopsisChapter 1: Introduction.- Chapter 2 : Rodent Models of Down Syndrome I: Mouse & Rat.- Chapter 3: Rodent Models of Down Syndrome II: Mouse.- Chapter 4: Rodent Models of Down Syndrome III: Mouse.- Chapter 5: Modeling Down Syndrome in C. elegans.- Chapter 6: Modeling Down Syndrome in Drosophila.- Chapter 7: Zebrafish Models of Down Syndrome.- Chapter 8: Using Human Brain organoids to Study Down Syndrome.- Chapter 9: Cellular Models: Stem Cells and other Cellular Models.-Chapter 10: Conclusions and Perspectives.

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Book SynopsisPart 1: Introduction.- Chapter 1. The oral microbiome and us.- Part 2: Symbiosis.- Chapter 2. Acquisition of the oral microbiome.- Chapter 3. Symbiosis between the oral microbiome and the human host: microbial homeostasis and stability of the host.- Chapter 4. The Impact of Diet and Nutrition on the Oral Microbiome.- Chapter 5. Link between oral and gut microbiome: the Oral-Gut Axes.- Chapter 6. Nitrite production from nitrate in the oral microbiome and its contribution to oral and systemic health.- Chapter 7. Positive role of saliva in the oral microbiome.- Part 3. Dysbiosis.- Chapter 8. Interaction of the systemic inflammatory state, inflammatory mediators and the oral microbiome.- Chapter 9. The Oral Microbiome: A Key Determinant of Oral Health.- Chapter 10. Oral microbiome and cancer.- Chapter 11. Oral disease and its association with cognitive decline and dementia.- Chapter 12. Dysbiosis of oral microbiome/citrullination and links to Rheumatoid arthritis.- Chapter 13. The Oral Microbiome in Diabetes, Arterial Hypertension, and Obesity: A Scoping Review. Chapter 14. Hormonal environment shapes the oral microbiome.- Part 4. Microbiome interventions for maintaining oral and systemic health.- Chapter 15. Periodontal treatment to improve general health and systematic diseases.- Chapter 16. Effects of antimicrobial agents used for dental treatments - Impacts on the human oral ecosystem and the resistome.- Chapter 17. Modulation of the Human Microbiome: Probiotics, Prebiotics, and Microbial Transplants.

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Book SynopsisTable of Contents1. Die Hauptmerkmale der Vögel.- 2. Vom Vogelnest.- Wie die Vögel schlafen. Verschiedene Nistweisen. Nestbau und Brutgewohnheiten. Gelege und Eiablage..- 3. Die Brut.- 4. Über Nesttreue, Lahmstellen, Nest-Irrungen.- 5. Kennt der Vogel seine Eier ?.- 6. Erkennt der Vogel seine Jungen?.- 7. Wer füttert und führt die Jungen ?.- 8. Hängt die Brutdauer von der Größe des Vogels ab ?.- 9. Hängt die Eigröße von der Größe des Vogels ab ?.- 10. Vögel, die in fremde Nester legen.- Das Kuckucksei. Der junge Kuckuck und seine Pflegeeltern..- 11. Vogelmischlinge und -zwitter.- 12. Paarbildung und Ehe.- Ehigkeit. Ortsehe. Zeitehe. Dauerehe. Keinehigkeit. Balz..- Beispiele: Gans, Stockente, Tauben (Kropfmilch)..- 13. Über das Ei und das Wachstum der Jungen.- Schalendicke. Dotter und Eiweiß. Kükendotter. Wachstums-geschwindigkeit der Jungen. Nahrungsverbrauch. Feder-wachstum..- 14. Der Federwechsel (die Mauser).- Gleichzeitiger und allmählicher Wechsel der Schwung- und Schwanzfedern. Mauserzeit. Jugendmauser..- 15. Farbenmuster und Umfärbung.- Federfarbstoffe. Strukturfarben. Abnutzung. Federscharten. Ausblassen. Zustandekommen des Zeichnungsmusters. Verschiedenheit nach Alter und Geschlecht. Hahnenfiedrigkeit, Daunenfarbe. Tonerzeugende Federn..- 16. Gefiederpflege.- Einfetten. Einpudern. Baden. Kratzen. Schütteln. Sich strecken..- 17. Ernährungsweise der Vögel.- Zerkleinerung der Nahrung. Kropf. Blinddärme. Fleisch- und Pflanzenfresser. Gewölle..- 18. Verständigungsweisen der Vögel.- Stimmlaute und ihre Bedeutung (Huhn, Gans, Enten). Stimmerzeugung. Einzel- und Siedlungsbrüter. Ausdrucksbewegungen. Gesang. Tonnachahmung (Spotten, Sprechen)..- 19. Die Sinneswerkzeuge der Vögel.- Geruch. Geschmack. Tastgefühl. Gesichtssinn. Gehör. Verhalten bei Wärme und Kälte..- 20. Bewegungsweisen.- Laufen.- Klettern.- Fliegen.- Bau der Flügel und Flugfedern. Flugweisen. Fluggeschwindigkeit..- Schwimmen und Tauchen.- Spezifisches Gewicht, Schwimmweisen, Tauchleistungen..- 21. Die geistigen Fähigkeiten.- „Klugheit“ und „Dummheit“. Triebhandlungen. Selbst-dressur..- 22. Wie findet sich ein Vogel zurecht ?.- Nahorientierung. Wiederfinden der Brut- und Winterheimat. Verfrachtungsversuche..- Verzeichnis der wissenschaftlichen Namen, zugleich Seitenweiser.

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Book SynopsisA kitchen is no different from most science laboratories and cookery may properly be regarded as an experimental science. Food preparation and cookery involve many processes which are well described by the physical sciences. Understanding the chemistry and physics of cooking should lead to improvements in performance in the kitchen. For those of us who wish to know why certain recipes work and perhaps more importantly why others fail, appreciating the underlying physical processes will inevitably help in unravelling the mysteries of the "art" of good cooking. Strong praise from the reviewers - "Will be stimulating for amateur cooks with an interest in following recipes and understanding how they work. They will find anecdotes and, sprinkled throughout the book, scientific points of information... The book is a pleasant read and is an invitation to become better acquainted with the science of cooking." - NATURE "This year, at last, we have a book which shows how a practical understanding of physics and chemistry can improve culinary performance… [Barham] first explains, in a lucid non-textbooky way, the principles behind taste, flavour and the main methods of food preparation, and then gives fool-proof basic recipes for dishes from roast leg of lab to chocolate soufflé." - FINANCIAL TIMES WEEKEND "This book is full of interesting and relevant facts that clarify the techniques of cooking that lead to the texture, taste and aroma of good cuisine. As a physicist the author introduces the importance of models in preparing food, and their modification as a result of testing (tasting)."- THE PHYSICIST "Focuses quite specifically on the physics and food chemistry of practical domestic cooking in terms of real recipes... Each chapter starts with an overview of the scientific issues relevant to that food group, e.g. toughness of meat, thickening of sauces, collapse of sponge cakes and soufflés. This is followed by actual recipes, with the purpose behind each ingredient and technique explained, and each recipe followed by a table describing some common problems, causes and solutions. Each chapter then ends with suggested experiments to illustrate some of the scientific principles exploited in the chapter." - FOOD & DRINK NEWSLETTER Trade ReviewFrom the reviews:“The Science of Cooking is organized into two distinct sections, with an introduction and ancillary material. … The helpful Glossary provides basic definitions of chemical terms that many cooks may not have encountered. … ‘Foodies’, chemists who are interested in food, and serious cooks will enjoy the spirit of this book.” (Cheryl Baldwin Frech, Journal of Chemical Education, Vol. 81 (4), April, 2004)"This year, at last, we have a book which shows how a practical understanding of physics and chemistry can improve culinary performance… [Barham] first explains, in a lucid non-textbooky way, the principles behind taste, flavour and the main methods of food preparation, and then gives fool-proof basic recipes for dishes from roast leg of lab to chocolate soufflé."- FINANCIAL TIMES WEEKEND"This book is full of interesting and relevant facts that clarify the techniques of cooking that lead to the texture, taste and aroma of good cuisine. As a physicist the author introduces the importance of models in preparing food, and their modification as a result of testing (tasting)."-THE PHYSICIST"Focuses quite specifically on the physics and food chemistry of practical domestic cooking in terms of real recipes. Industrial food technologists and process engineers will not find design equations or process flowsheets. Instead they, and those with more immediate home cooking interests, will find a clear, fascinating, informative and serviceable description of the scientific phenomena occurring during domestic cooking, and how to exploit an understanding thereof to achieve results consistently, adapt recipes confidently and adeptly rescue catastrophes. Each chapter starts with an overview of the scientific issues relevant to that food group, e.g. toughness of meat, thickening of sauces, collapse of sponge cakes and soufflés. This is followed by actual recipes, with the purpose behind each ingredient and technique explained, and each recipe followed by a table describing some common problems, causes and solutions. Each chapter then ends with suggested experiments to illustrate some of the scientific principles exploited in the chapter."-FOOD & DRINK NEWSLETTER"Will be stimulating for amateur cooks with an interest in following recipes and understanding how they work. They will find anecdotes and, sprinkled throughout the book, scientific points of information... The book is a pleasant read and is an invitation to become better acquainted with the science of cooking."-NATURE"You do not have to be a chemist or a physicist to cook a meal, any more than you need a qualification in engineering to drive a car; but in both cases, a little technical knowledge can help when things go wrong. That is the reasoning behind this odd volume that combines an explanation of the scientific principles of cooking with a down-to-earth guide to kitchen utensils, ... some experiments to try at home, and a random collection of around 40 recipes."-THE ECONOMIST"I believe that cooking is a bit like this: it is natural ability, not scientific knowledge that makes a good cook. Not withstanding, as physicists who are always asking "why is it so?," this book is full of interesting and relevant facts that clarify the techniques of cooking that lead to the texture, taste and aroma of good cuisine. As a physicist the author introduces the importance of models in preparing food, and their modification as a result of testing (tasting)" - THE PHYSICIST"…At last, we have a book which shows how a practical understanding of physics and chemistry can improve culinary performance … [Barham] first explains, in a lucid non-textbooky way, the principles behind taste, flavour and the main methods of food preparation, and then gives fool-proof basic recipes for dishes from roast leg of lab to chocolate soufflé."–Financial Times Weekend"Will be stimulating for amateur cooks with an interest in following recipes and understanding how they work. They will find anecdotes and, sprinkled throughout the book, scientific points of information...The book is a pleasant read and is an invitation to become better acquainted with the science of cooking."–NatureTable of Contents1 Introduction.- 2 Sensuous Molecules — Molecular Gastronomy.- 3 Taste and Flavour.- 4 Heating and Eating — Physical Gastronomy.- 5 Cooking methods and utensils.- 6 Meat and Poultry.- 7 Fish.- 8 Breads.- 9 Sauces.- 10 Sponge Cakes.- 11 Pastry.- 12 Soufflés.- 13 Cooking with Chocolate.- Weights and Measurements.- Glossary of Terms.

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Book Synopsis Vertiefung der „Kurzgefassten Statistik" von Jürgen Bortz Auch ohne mathematische Vorkenntnisse verständlich Mit 47 Signifikanztafeln Table of Contents1. Wahrscheinlichkeitslehre.- 2. Beobachtungen, Hypothesen und Tests.- 3. Datenerhebung und Datenaufbereitung.- 4. Verteilungsfreie und parametrische Tests.- 5. Analyse von Häufigkeiten.- 6. Analyse von Rangdaten.- 7. Analyse von Meßwerten.- 8. Zusammenhangsmaße und Regression.- 9. Urteilerübereinstimmung.- 10. Verteilungsfreie Sequenzanalyse.- 11. Abfolgen und Zeitreihen.- Anhang (47 Signifikanzfafeln).

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Book SynopsisVielfach genutzt für die Verarbeitung von Daten in Tabellenform, war Excel bisher für statistische Analysen weniger geeignet. Seit 2009 kann mit dem Add-In RExcel die Statistiksoftware R eingebunden werden. Der Band bietet die erste Einführung auf Deutsch zur Benutzung der RExcel-Oberfläche. Anhand eines Beispieldatensatzes aus der Herz-Kreislaufforschung werden Deskriptive Statistik, Korrelation und Regression, statistische Tests, Überlebenszeitanalyse sowie Fallzahlplanung nachvollziehbar dargestellt. Mit Schritt-für Schritt-Anleitungen und Tipps.Table of ContentsAllgemeine Information.- RExcel starten und beenden.- Datenverwaltung mit Excel und RExcel.- Datenmanagement in Excel bzw. R-Commander.- Vorbemerkungen und Informationen zur statistischen Analyse medizinischer Daten.- Deskriptive Statistik.- Zusammenhang von Variablen.- Statistische Tests für unabhängige Beobachtungen.- Statistische Tests für abhängige Beobachtungen.- Einstichprobentests und Konfidenzintervalle.- Überlebenszeitanalyse.- Fallzahlberechnungen.- Anhang.- Stichwortverzeichnis.

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Book SynopsisA kitchen is no different from most science laboratories and cookery may properly be regarded as an experimental science. Food preparation and cookery involve many processes which are well described by the physical sciences. Understanding the chemistry and physics of cooking should lead to improvements in performance in the kitchen. For those of us who wish to know why certain recipes work and perhaps more importantly why others fail, appreciating the underlying physical processes will inevitably help in unravelling the mysteries of the "art" of good cooking. Strong praise from the reviewers - "Will be stimulating for amateur cooks with an interest in following recipes and understanding how they work. They will find anecdotes and, sprinkled throughout the book, scientific points of information... The book is a pleasant read and is an invitation to become better acquainted with the science of cooking." - NATURE "This year, at last, we have a book which shows how a practical understanding of physics and chemistry can improve culinary performance… [Barham] first explains, in a lucid non-textbooky way, the principles behind taste, flavour and the main methods of food preparation, and then gives fool-proof basic recipes for dishes from roast leg of lab to chocolate soufflé." - FINANCIAL TIMES WEEKEND "This book is full of interesting and relevant facts that clarify the techniques of cooking that lead to the texture, taste and aroma of good cuisine. As a physicist the author introduces the importance of models in preparing food, and their modification as a result of testing (tasting)."- THE PHYSICIST "Focuses quite specifically on the physics and food chemistry of practical domestic cooking in terms of real recipes... Each chapter starts with an overview of the scientific issues relevant to that food group, e.g. toughness of meat, thickening of sauces, collapse of sponge cakes and soufflés. This is followed by actual recipes, with the purpose behind each ingredient and technique explained, and each recipe followed by a table describing some common problems, causes and solutions. Each chapter then ends with suggested experiments to illustrate some of the scientific principles exploited in the chapter." - FOOD & DRINK NEWSLETTER Trade ReviewFrom the reviews:“The Science of Cooking is organized into two distinct sections, with an introduction and ancillary material. … The helpful Glossary provides basic definitions of chemical terms that many cooks may not have encountered. … ‘Foodies’, chemists who are interested in food, and serious cooks will enjoy the spirit of this book.” (Cheryl Baldwin Frech, Journal of Chemical Education, Vol. 81 (4), April, 2004)"This year, at last, we have a book which shows how a practical understanding of physics and chemistry can improve culinary performance… [Barham] first explains, in a lucid non-textbooky way, the principles behind taste, flavour and the main methods of food preparation, and then gives fool-proof basic recipes for dishes from roast leg of lab to chocolate soufflé."- FINANCIAL TIMES WEEKEND"This book is full of interesting and relevant facts that clarify the techniques of cooking that lead to the texture, taste and aroma of good cuisine. As a physicist the author introduces the importance of models in preparing food, and their modification as a result of testing (tasting)."-THE PHYSICIST"Focuses quite specifically on the physics and food chemistry of practical domestic cooking in terms of real recipes. Industrial food technologists and process engineers will not find design equations or process flowsheets. Instead they, and those with more immediate home cooking interests, will find a clear, fascinating, informative and serviceable description of the scientific phenomena occurring during domestic cooking, and how to exploit an understanding thereof to achieve results consistently, adapt recipes confidently and adeptly rescue catastrophes. Each chapter starts with an overview of the scientific issues relevant to that food group, e.g. toughness of meat, thickening of sauces, collapse of sponge cakes and soufflés. This is followed by actual recipes, with the purpose behind each ingredient and technique explained, and each recipe followed by a table describing some common problems, causes and solutions. Each chapter then ends with suggested experiments to illustrate some of the scientific principles exploited in the chapter."-FOOD & DRINK NEWSLETTER"Will be stimulating for amateur cooks with an interest in following recipes and understanding how they work. They will find anecdotes and, sprinkled throughout the book, scientific points of information... The book is a pleasant read and is an invitation to become better acquainted with the science of cooking."-NATURE"You do not have to be a chemist or a physicist to cook a meal, any more than you need a qualification in engineering to drive a car; but in both cases, a little technical knowledge can help when things go wrong. That is the reasoning behind this odd volume that combines an explanation of the scientific principles of cooking with a down-to-earth guide to kitchen utensils, ... some experiments to try at home, and a random collection of around 40 recipes."-THE ECONOMIST"I believe that cooking is a bit like this: it is natural ability, not scientific knowledge that makes a good cook. Not withstanding, as physicists who are always asking "why is it so?," this book is full of interesting and relevant facts that clarify the techniques of cooking that lead to the texture, taste and aroma of good cuisine. As a physicist the author introduces the importance of models in preparing food, and their modification as a result of testing (tasting)" - THE PHYSICIST"…At last, we have a book which shows how a practical understanding of physics and chemistry can improve culinary performance … [Barham] first explains, in a lucid non-textbooky way, the principles behind taste, flavour and the main methods of food preparation, and then gives fool-proof basic recipes for dishes from roast leg of lab to chocolate soufflé."–Financial Times Weekend"Will be stimulating for amateur cooks with an interest in following recipes and understanding how they work. They will find anecdotes and, sprinkled throughout the book, scientific points of information...The book is a pleasant read and is an invitation to become better acquainted with the science of cooking."–NatureTable of Contents1 Introduction.- 2 Sensuous Molecules — Molecular Gastronomy.- 3 Taste and Flavour.- 4 Heating and Eating — Physical Gastronomy.- 5 Cooking methods and utensils.- 6 Meat and Poultry.- 7 Fish.- 8 Breads.- 9 Sauces.- 10 Sponge Cakes.- 11 Pastry.- 12 Soufflés.- 13 Cooking with Chocolate.- Weights and Measurements.- Glossary of Terms.

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Book SynopsisThis book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The frequent occurrence of inactivated p53 implicates this gene product in the genesis of many human cancers. The p53 gene can suppress the growth of cancer cells and the transformation process by oncogenes. The p53 protein is a transcription factor that can repress or activate promoters containing one of three p53 DNA-binding motifs. The activity of p53 is regulated by phosphorylation and other transcription factors. Replacement of the p53 function or restoration of the p53 biochemical pathway is a focus of gene therapy.Table of Contents1. The Role of p53 in Cancer.- 2. Gene Structure.- 3. Wild-Type versus Mutant p53.- 4. Biophysical and Biochemical Properties of the p53 Protein.- 5. Regulation and Modulation of the Function of p53.- 6. Potential Clinical Significance of the p53 Tumor Suppressor Gene in Cancer Patients.

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Table of ContentsPterine als Wirkstoffe und Pigmente.- The structure and biological activity of immunoglobulins and their subunits.- Inhibitors of adrenal cortical function.- The biosynthesis of cholesterol.- Transepithelial transport and its hormonal control in toad bladder.- Production, storage and release of anterior pituitary hormones.- The adipokinetic property of hypophyseal peptides.

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Book SynopsisWhen new fellows join my lab, I give them some reading materials so that they can orient themselves in their assignment in a new eld. When fellows leave my lab, some after writing their dissertations, I prefer to give them a book as a symbolic present. I was longing for a book that contained something on more or less eve- thing about the islets. At the same time, I wished it contained information as recent as possible. There are a few such books in the market but they are pretty outdated. I started picking islets myself from October 1990, when I joined the Rolf Luft Center, Karolinska Institutet. Over the years my fascination for islet research remained high. Since last year, I felt a stronger urge to do more for these mysterious and hidden mini-organs that are directly or indirectly involved in the pathogenesis of all forms of diabetes that affects ?250 million people in the world. After I launched the Islet (landesbioscience. com/journals/islets) and founded the Islet Society (isletso- ety. org), there was a momentum that could be utilized to create something equally meaningful i. e. this book. The idea cracked in September 2008. Starting September 19, 2008, I contacted an estimated 90% of the authors who published anything on the islets during 2007–2008 and who could be traced from the internet.Trade Review"It looks very comprehensive and covers all current areas of interest and includes chapters written by world renowned contributors - very nice!"Matthias von Herrath, MDProfessor and Director, Center for Type 1 Diabetes ResearchLa Jolla Institute for Allergy and Immunology, La Jolla CA, USA "This book will be welcomed by islet researchers and clinicians interested in the latest developments and theories from which new therapeutics for diabetes can emerge". Martha Pavlakis, MDAssociate Professor of Medicine, Harvard Medical SchoolMedical Director, Kidney and Pancreas TransplantationBeth Israel Deaconess Medical CenterBoston, MA, USA "The field of islet biology is assuming increasing importance with the recognition that beta-cell dysfunction is a critical feature of type II diabetes. Improving b-cell function and/or b-cell mass may be the best approach to treating diabetes. Thus, the publication of a book covering so many aspects of this field is timely". Fred Levine, M.D., Ph.D.Professor, Burnham Institute for Medical ResearchDirector, Sanford Children's Health Research CenterLa Jolla, CA, USA "The growing prevalence of both type 1 and type 2 diabetes make islet cell biology a critical concern for a wide range of scientists and health professionals. From anatomy and developmental biology, through islet physiology and biochemistry, to issues of immunology and transplantation, this book is a terrific resource".Jonathan M.W.Slack, Ph.D., F.Med.Sci. Director, Stem Cell Institute, University of Minnesota, Medical SchoolMinneapolis, MN, USA "This book allows you to enjoy an adventurous and instructive guided tour in the archipelago of the islets of Langerhans. A team of expert and enthusiastic explorers will not only conduct the voyager through almost all niches of this complex and fascinating environment, but also provide him with clues and keys for future exploration of still hidden sites".Prof. Pellegrino MasielloDept. of Experimental Pathology,University of Pisa,Pisa, Italy "The pancreatic islet is a complex mini-organ whose dysfunction is critical in all forms of diabetes. This book provides a comprehensive review of the molecular and cellular processes in islet development, gene expression, and physiology and reviews how a better understanding of the pancreatic islet will advance efforts to develop new therapeutic approaches for diabetes. This book should be quite useful for anyone interested in the pancreatic islet or diabetes".Alvin C. Powers, M.D.Joe C. Davis Chair in Biomedical Science Professor of Medicine, Molecular Physiology and BiophysicsDirector, Vanderbilt Diabetes CenterVanderbilt UniversityNashville, TN USA "A very timely book on the Islet of Langerhans that coincides with the realization that pancreatic ß-cell failure is key to all forms of diabetes mellitus and research in the field is exploding. It contains very thoughtful chapters, each by renown experts in their field, and tackles the complexity of this micro-organ in health and disease very comprehensively and thoughtfully. It will likely become a Reference for years to come for basic researchers, clinicians and students interested is diabetes research"Marc Prentki, PhDProfessor of Nutrition and BiochemistryCanada Research Chair in Diabetes and MetabolismMDRC DirectorMontreal, QCCanada Table of ContentsCHAPTER 1 : Microscopic anatomy of the human islet of Langerhans - Peter In't Veld and Miriam Marichal CHAPTER 2 : The comparative anatomy of islets - Scott Heller CHAPTER 3: Approaches for imaging of islets: recent advances and future prospects - Ulf Ahlgren and Martin Gotthardt CHAPTER 4: Islet-cell Development - Anabel Rojas, Adrian Khoo, Juan R. Tejedo, Francisco J. Bedoya, Bernat Soria and Franz Martín CHAPTER 5: High fat programming of b-cell failure - Marlon. E. Cerf CHAPTER 6: Nutrient regulation of insulin secretion and b-cell functional integrity - Philip Newsholme, Celine Gaudel, and Neville H McClenaghan CHAPTER 7: Electrophysiology of islet cells - Gisela Drews, Peter Krippeit-Drews and Martina Düfer CHAPTER 8: ATP sensitive potassium channels in health and disease - Rebecca Clark and Peter Proks CHAPTER 9: Role of mitochondria in b-cell function and dysfunction - Pierre Maechler, Ning Li, Marina Casimir, Laurène Vetterli, Francesca Frigerio, Thierry Brun CHAPTER 10: Basement membrane in pancreatic islet function - Martin Kragl and Eckhard Lammert CHAPTER 11: Calcium signaling in the islets - Md. Shahidul Islam CHAPTER 12: Electrical bursting, calcium oscillations, and synchronization of pancreatic islets - Richard Bertram, Arthur Sherman, and Leslie S. Satin CHAPTER 13: Cyclic AMP signaling in pancreatic islets - Brian Furman, Wee Kiat Ong, and Nigel Pyne CHAPTER 14: Exocytosis in islet b-cells - Haruo Kasai, Hiroyasu Hatakeyama, Mitsuyo Ohno and Noriko Takahashi CHAPTER 15: The novel roles of glucagon-like peptide-1, angiotensin II, and vitamin D in islet function - Po Sing Leung CHAPTER 16: Proteomics and islets research - Meftun Ahmed CHAPTER 17: Wnt signaling in pancreatic islets - Zhengyu Liu and Joel F. Habener CHAPTER 18: Molecular pathways underlying the pathogenesis of pancreatic a-cell dysfunction - Dan Kawamori,Hannah J. Welters, and Rohit N. Kulkarni CHAPTER 19: Mechanisms of pancreatic b-cell apoptosis in diabetes and its therapies - James D. Johnson, Dan S. Luciani CHAPTER 20: b-cell function in obese-hyperglycaemic mice [ob/ob mice] - Per Lindström CHAPTER 21: Islet structure and function in the GK rat - B. Portha, G. Lacraz, A. Chavey, F. Figeac, M. Fradet, C. Tourrel-Cuzin, F. Homo-Delarche, M-H. Giroix, D. Bailbé, MN. Gangnerau, J. Movassat CHAPTER 22: The b-cell in human type 2 diabetes - Piero Marchetti, Roberto Lupi, Silvia Del Guerra, Marco Bugliani, Lorella Marselli and Ugo Boggi CHAPTER 23: Clinical approaches to preserve b-cell function in diabetes - Bernardo L. Wajchenberg CHAPTER 24: Immunology of b-cell destruction - Daria La Torre, and Åke Lenmark CHAPTER 25: Toll-like receptors and type 1 diabetes - Danny Zipris CHAPTER 26: Prevention of b-cell destruction in autoimmune diabetes: current approaches and future prospects - Saikiran K Sedimbi and Carani B Sanjeevi CHAPTER 27: In vivo regeneration of insulin-producing b-cell - Hee-Sook Jun CHAPTER 28: Customized cell-based treatment options to combat autoimmunity and restore b-cell function in Type I diabetes mellitus: current protocols and future perspectives - Fred Fändrich and Hendrik Ungefroren CHAPTER 29: The progammable cell of monocytic origin (PCMO): A potential adult stem/progenitor cell source for the generation of islet cells - Hendrik Ungefroren and Fred Fändrich CHAPTER 30: Islet isolation for clinical transplantation - Tatsuya Kin CHAPTER 31: Human islet autotransplantation: the trail thus far and the highway ahead - Martin Hermann, Raimund Margreiter and Paul Hengster CHAPTER 32: Modulation of early inflammatory reactions to promote engraftment and function of transplanted pancreatic islets in autoimmune diabetes - Lorenzo Piemonti, Luca G. Guidotti,

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Book Synopsis1. Clinical Pharmacokinetics.- 2. Essential medicines and rational use of drugs.- 3. Drug Information Centre.- 4. Evidence-Based Medicine.- 5. Medication Adherence.- 6. Therapeutic Drug Monitoring.- 7. Medication Error.- 8. Drug use in pregnancy and lactation (Perinatal pharmacology) .- 9. Pediatric Pharmacology.- 10. Geriatric Pharmacology.- 11. Usage of drugs in various Pathological States.- 12. High throughput screening and computer-aided drug designing.- 13. Phase 0 Clinical Trials.- 14. Phase 1 Clinical Trials.- 15. Phase 2 Clinical Trials.- 16. Phase 3 Clinical Trials.- 17. Phase 4 Clinical trials.- 18. Ethics in Clinical Trials.- 19. Vaccine Clinical Trials.- 20. Real-World Evidence Studies and Pragmatic Clinical Trials.- 21. Contract Research Organizations - Roles & Responsibilities.- 22.  Bioavailability and Bioequivalence Studies.- 23. New Drugs and Clinical trial rules 2019.- 24. Regulation of healthcare products by the United States Food and Drug Administration and Health Canada.- 25. Regulation of healthcare products by the United States Food and Drug Administration and Health Canada.- 26. Medical Device and Medical Device Regulations.- 27. Off-Label Use of Drugs.- 28. Nonclinical testing methods to assess safety and efficacy of new drugs.- 29. Novel Chemical and Biological Entities in the Past Five Years.- 30. Drug Repurposing.- 31. Specialized Drug Delivery System .- 32. Biologicals and Biosimilars.

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Book SynopsisChapter 1. Introduction.- Chapter 2. Molecular composition and characteristics of marine shellfish protein.- Chapter 3. Digestion and absorption of marine shellfish protein.- Chapter 4. Preparation and identification of marine shellfish peptides.- Chapter 5. Marine shellfish peptides and bone health.- Chapter 6. Marine shellfish peptides and hypertension.- Chapter 7. Marine shellfish peptides and thrombus.- Chapter 8. Marine shellfish peptides and gout.- Chapter 9. Marine shellfish protein and taste peptides.- Chapter 10. Processing and application of marine shellfish protein.- Chapter 11. Sensitization and control of marine shellfish proteins.

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Book SynopsisChapter 1 Historical overview of RNA therapeutics.- Chapter 2 RNA: an introduction.- Chapter 3 RNA in the central dogma: mRNA.- Chapter 4 RNA in the central dogma: tRNA.- Chapter 5 non-coding RNAs: long non-coding RNAs.- Chapter 6 non-coding RNAs: microRNAs.- Chapter 7 non-coding RNAs: circular RNAs.- Chapter 8 non-coding RNAs: small interfering RNAs.- Chapter 9 non-coding RNAs: tiRNAs.- Chapter 10 non-coding RNAs: glycanRNAs.- Chapter 11 emerging noncoding RNAs: piRNAs, snoRNAs, xist RNAs.- Chapter 12 extracellular RNAs: biogenenesis.- Chapter 13 extracellular RNAs: functions, crosstalks and therapeutic potential.- Chapter 14 Distinguishing functional roles of protein-coding vs. non-coding RNAs: the possibility of bifunctional RNAs.- Chapter 15 RNA modifications in human diseases.- Chapter 16 RNA screening design.- Chapter 17 single-cell RNA sequencing (sc-RNAseq) in the development of biomedical therapeutics.- Chapter 18 RNA-ligand molecular docking.- Chapter 19 RNA imaging technologies.- Chapter 20 RNA-based imaging system.- Chapter 21 Targeting RNA with small molecules: fundamental principles.- Chapter 22 RNA bio-conjugation: current development in siRNA therapeutics.-Chapter 23 RNA nanotechnology: the fundamentals.- Chapter 24 RNA nanotechnology: biomedical application.- Chapter 25 Current development of RNA delivery systems.- Chapter 26 mRNA vaccines.- Chapter 27 circRNA vaccines.- Chapter 28 Cancer biomarker based on ncRNA liquid biopsy.- Chapter 29 Clinical RNAseq: from molecular basis to clinic.- Chapter 30  Utilization of AI in designing RNA therapeutics.

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Book SynopsisPart I. Introduction of NIRF Imaging.- Chapter 1. Historical Evolution.- Chapter 2. Advantages and Limitations vs Other Medical Imaging Techniques.- Part II. Principles of NIRF Imaging.- Chapter 3. Fluorophores Used in NIRF Imaging.- Chapter 4. Instrumentation for NIRF Imaging.- Part III. Functional Imaging with NIRF in Cancer.- Chapter 5. NIRF Specific Targets.- Chapter 6. Sensing pH Changes.-  Chapter 7. NIRF Imaging of Apoptosis.- Chapter 8. Functional Imaging with NIRF in Cancer Glucose Metabolism.- Chapter 9. Imaging of Cell Cycle.- Part IV. Clinical Application of NIRF Imaging Guided Surgery.- Chapter 10. Breast cancer.-  Chapter 11. Gyenecological Cancers.- Chapter 12. Intracranial cancer.- Chapter 13. Hepato-bililary tumors and pancreatic cancer.- Chapter 14. Head and Neck Cancer.- Chapter 15. Gastrointestinal cancer.- Chapter 16. Genitourinary Cancer.- Chapter 17. Lung Cancer.

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Book Synopsis1. Translational Omics - Precision and All ‘Coming of Age’.- 2. Beyond the Genome: Exploring the Multi-Omics Landscape.- 3. Disease Dynamics: Insights from Microbiome and Multi-omics Analysis.- 4. Multiresolution Insights into Single-Cell Landscapes: Integrating Genomics, Epigenomics and Proteomics for Brain Studies.- 5. Multi-omics Applications in Drug Discovery and Development.- 6. Machine Learning Approaches for the Diagnosis of Pre- and Post-covid-19 Phases.- 7. Exploring Human Brain Disorders Through Multi-Omics Approaches.- 8. Applications of Multi-omics in Human Genetic Disorders.- 9. Metabolomics Approaches for Microbiome Analysis.- 10. Brain Microbiome in Health and Disease: A Multi-Omics Perspective.- 11. Microbiome Dynamics in Colorectal Cancer: Implications for Personalized Treatment and Multi-omics Analysis.- 12. Human–Environment Interactions: A Multi-Omics and Interactome Perspective.- 13. Bioremediation- A Boon For A Sustainable Environment.- 14. Multi-Omics Applications in Environmental Sustainability.- 15. A Review on Root Phenomics: Understanding Plant Root Systems.- 16. Envisioning Production of Alginates Through the Lens of Multi-omics.- 17. Proteomics and Bioinformatics Approaches for Exploring Resilience Strategies in Cyanobacteria.-18. Advancements and Trends in Omics of Cyanobacterial Ultraviolet-Screening Compounds, Scytonemin and Mycosporine-like amino acids.- 19. Metabolomics: An Approach to Improve Production of Cyanobacterial Natural Products.- 20. Importance of Omics in Microalgal Biofuel Production.- 21. Lichen Symbiosis: A Systems Biology Perspective.

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Book SynopsisChapter 1. Introduction of Intelligent Biomaterials.- Chapter 2. Shape Memory Biomaterials.- Chapter 3. Intelligent Biomaterials for Organ Regeneration and Tissue Engineering.- Chapter 4. Self-powered Biomaterials.- Chapter 5. Stimuli-Responsive Biomaterials.- Chapter 6. Biomimetic Materials.- Chapter 7. Interactive Biomaterials.- Chapter 8. Bio-sensing Materials.- Chapter 9. Intelligent Biomaterials in Diagnostic Systems.- Chapter 10. Intelligent Biomaterials and Microfluidic Technology.- Chapter 11. Micro/nanorobots.- Chapter 12. Future of Intelligent Biomaterials.

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Book Synopsis1. Introduction: A Brief Guide to Targets and Strategies of Functional Nucleic Acids Detection in Food Safety.- 2. Adaptable Methods to Extract Nucleic Acid Targets and Evaluate Quality.- 3. Basic Rules in Nucleic Acid-Mediated Amplification and Hybridization Methods in Food Safety Detection: A Review.- 4. Modified nucleic acids.- 5. Reference Materials: A Golden Criterion in Nucleic Acid Identification.- 6. Functional Nucleic Acid Enzyme.- 7. Reference Gene: In-Species Universality Versus Between-Species Uniquity.- 8. Super PCR.- 9. PCR-Based Technologies for Identifying Unknown Gene Sequences.- 10. Triplex Nucleic Acids.- 11. A Developed Accurate Digital PCR Detection Technology in Food Safety.- 12. Development of Accurate Nucleic Acid Detection Technology for Target Quantification.- 13. Recent Progress in High-Throughput Detection Technology for Food Safety.- 14. Detecting Targets Without Thermal Cycling in Food: Isothermal Amplification and Hybridization.- 15. Cell System-Based Biosensors for Food Safety.- 16. Aptamers and Their Application.- 17. Lateral Flow Nucleic Acid Biosensors.- 18. Nucleic Acid Biosensors for Food Safety.- 19. PCR Methods for Detecting GM Crops and Food in Agriculture and the Food Chain: A Review.- 20. The Identification and Detection Technology of Research in Microorganisms Including Living or Dead Bacteria.- 21. Characterization of Microbial Diversity in Food Chain: A Molecular Review.- 22. Identification and Assessment of Heavy Metal Pollution Using Nucleic Acid-Mediated Technologies.- 23. Genotoxicity Detection at the Molecular Level in Food Safety Assessment: Conventional Methods and Developments.- 24. A Molecular Review of the Detection of Specific Nucleic Acids by Amplification and Hybridization Characterization of Microbial Diversity in the Food Chain: A Molecular Review.

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Book SynopsisChapter 1. Chemical tools for decoding the functions of O-GlcNAcylation.- Chapter 2. Profiling O-GlcNAcylation with mass spectrometry.- Chapter 3. O-GlcNAcylation and cell metabolism.- Chapter 4. O-GlcNAcylation and transcriptional regulation and epigenetics.- Chapter 5. O-GlcNAcylation and signal transduction.- Chapter 6. O-GlcNAcylation and stem cells.- Chapter 7. O-GlcNAcylation and immune regulation.- Chapter 8. O-GlcNAcylation and neuronal development, neurodegeneration and neurological disorders.

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Book SynopsisIntroduction to Biosensors for Personalized Health.- Non-Invasive Biomarkers for Disease Diagnosis and Health Monitoring.- Affinity-based clinical biomarkers for early disease detection.- Fundamentals, Fabrication, Engineering, and Prototyping Aspects of Bioelectronics and Biosensors for Biomedical Analysis.- Signal Amplification Strategies for Biosensing of Clinically Important Analytes.-Materials for developing electrochemical biosensing systems.- Personalized on-chip sample evaluation devices for biomedical applications: advantages, challenges and opportunities.- Nanozyme mediated biosensing.- Mechanisms for analytes biosensing.- The development process of point-of-care sensor-based detection modules for biomedical diagnoses.- Biosensors for rapid and early detection of chronic diseases.- Advances in affinity-based biosensing mechanisms for direct detection /monitoring of the biomarkers.- Sweat, interstitial fluid, and saliva based wearable devices for continuous monitoring of metabolites and biomarkers.- Implantable biosensors for personalized healthcare.- Ingestible biosensors for personalized health.

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Book SynopsisChapter 1. Extracellular Vesicles: Tiny Packages with Big Potential.- Chapter 2. Regulation and Mechanisms of Exosome Cargo Selection and Secretion.- Chapter 3. Exosomes (Extracellular Vesicles): A Significant Mediator through Inter-organs communication in Mesenchymal Stem Cell Therapy.- Chapter 4. Extracellular vesicle isolation methods.- Chapter 5. Technologies for EV Surface Modification and Its Application in Targeted.- Chapter 6. Design of Artificial Extracellular Vesicles for Treatments of Cardiovascular Diseases.- Chapter 7. EV Tetraspanins in Regenerative Medicine.- Chapter 8. The mechanisms and applications of exosomes in dermatology.- Chapter 9. Stem cell-derived extracellular vesicles as therapeutics against renal diseases.- Chapter 10. Exosomes for ophthalmic therapeutics.- Chapter 11. The Role of Extracellular vesicles in inflammatory bowel diseases.- Chapter 12. The applications of exosomes in the treatment of autoimmune-mediated eye diseases.- Chapter 13. Extracellular Vesicles in Pregnancy: Functional Insights, Diagnostic Potential for Maternal-Fetal Disorders, and Therapeutic Implications.- Chapter 14. Extracellular vesicles in aging and age-related diseases.- Chapter 15. Extracellular vesicle imaging in theranostic applications.- Chapter 16. Extracellular vesicles: main challenges in industrialization.

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Book SynopsisChapter 1. Introduction to Ticks and Their Resistance to Acaricides.- Chapter 2. Basic biology of ticks.- Chapter 3. Acaricide Chemistry and Modes of Action.- Chapter  4. Mechanisms of Acaricide Resistance.- Chapter 5. Monitoring Acaricide Resistance.- Chapter 6. Managing acaricide resistance in the cattle tick, Rhipicephalus microplus (Acari: Ixodidae).- Chapter 7. Tick-Borne Diseases.- Chapter 8. Unlocking Tick Resistance with Transcriptome-Based Bioinformatics.- Chapter 9. Vaccines Against Ticks.- Chapter 10. Tick Inmunoendrocrinology: a Novel Approach to Develop Strate-gies to Control and Prevent Tick Infestations. Chapter 11. Exploring the Potential of Plant Extracts as Novel Bioacaricides.- Chapter 12. Using Entomopathogenic Fungi for Tick Control.

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