Diseases and disorders Books

Book SynopsisIncreasing numbers of people are turning to the use of dietary vegetables, medicinal herbs, and plant extracts to treat cancer. This title brings together a leading group of experts on the different aspects of nutrient supplementation, foods and plant extracts in cancer prevention and treatment.Table of ContentsContirbutors. Preface. Acknowledgments. Part I. Approaches to Cancer Prevention: Role of Nutrition. 1. Antioxidents as Cancer Therapies. 2. Cancer and Nutrition. 3. Vitimin E in Cancer Prevention and Treatment. 4. Chemical Versus Food Forms of Selenium in Cancer Prevention. 5. Nutients to Stimulate Cellular Immunity: Role in cancer Prevention and Therepy. 6. Nutrition and Skin Cancer Risk Prevention. 7. Nutritional Startegies for the Prevention of Cervical Cancer. Part II. Fruits, Vegetables, and Herbs in Cancer Prevention. 8. Tomato and Cancer. 9. The Role of Dietary Fiber in Colon cancer Prevention. 10. Soy Food and Breast cancer. 11. Prevention and Therepeutic Effects of Dietary Phytochemicals on Cancer Development. 12. Phytomedicines and Cancer Prevention. 13. Phytoesrogens and Cancer. 14. Herbals and Cancer Prevention. 15. Cruciferous Vegetables and Cancer Prevention. 16. Breast Cancer Prevention. Index.

Read more less

Book SynopsisChallenging traditional approaches to medical history, this work advances understandings of disease as a social and cultural construction in Latin America. It provides a look at the research in the history of medicine through essays about how disease was experienced and managed in different Latin American countries and regions, at different times.Trade Review“This book is an extraordinary contribution that brings together the very best scholars of Latin American public health and social history. Its emphasis on the social conditions that lead to epidemic disease as well as the political and social forces that shape practice is a welcome corrective to a literature still too often dominated by positivist traditions.”—David Rosner, director of the Center for the History and Ethics of Public Health, Columbia University”I was fascinated by all the essays in Disease in the History of Modern Latin America. They are theoretically aware and sophisticated while they remain accessible and oriented to the complexity of historical experience. This collection is a powerful argument for the richness of an interdisciplinary approach to cultural history.”—Daniel James, author of Doña Maria's Story: Life History, Memory, and Political IdentityTable of ContentsPreface vii Disease in the Historiography of Modern Latin America / Diego Armus 1 “The Only Serious Terror in These Regions”: Malaria Control in the Brazilian Amazon / Nancy Leys Stepan 25 An Imaginary Plague in Turn-of-the-Century Buenos Aires: Hysteria, Discipline, and Languages of the Body / Gabriella Nouzeilles 51 Tropical Medicine in Brazil: The Case of Chagas’ Disease / Marilia Coutinho 76 Tango, Gender, and Tuberculosis in Buenos Aires, 1900–1940 / Diego Armus 101 The State, Physicians. and Leprosy in Modern Colombia / Diana Obregón 130 Revolution, the Scatological Way: The Rockefeller Foundation’s Hookworm Campaign in 1920s Mexico / Anne-Emanuelle Birn 158 Between Risk and Confession: State and Popular Perspectives of Syphilis Infection in Revolutionary Mexico / Katherine Elaine Bliss 183 Dying of Sadness: Hospitalism and Child Welfare in Mexico City, 1920-1940 / Ann S. Blum 209 Mental Illness and Democracy in Bolivia: The Manicomio Pacheco, 1935–1950 / Ann Zulawski 237 Stigma and Blame during an Epidemic: Cholera in Peru, 1991 / Marcus Cueto 268 Nation, Science, and Sex: AIDS and the New Brazilian Sexuality / Patrick Larvie 290 Contributors 315 Index 317

Read more less

Book SynopsisIn this provocative collection of essays, François Delaporte shows how every epistemological concern demands its own mode of engagement. Through six seemingly disparate cases, Figures of Medicine reanimates the methodological and intellectual stakes at the core of the history of science and medicine.Trade Review"As always with Delaporte the scholarship is impressive, innovative and impeccable, and the analyses acute." -- -Camille Limoges Centre interuniversitaire de recherche sur la science et la technologie (CIRST-UQAM) Montreal "Lucid, focused, and rigorous ... An outstanding book that makes important contributions to intellectual history, the history of medicine, and their methodologies." -- -Jonathan Strauss Miami University

Read more less

Book SynopsisIn this provocative collection of essays, François Delaporte shows how every epistemological concern demands its own mode of engagement. Through six seemingly disparate cases, Figures of Medicine reanimates the methodological and intellectual stakes at the core of the history of science and medicine.Trade Review"As always with Delaporte the scholarship is impressive, innovative and impeccable, and the analyses acute." -- -Camille Limoges Centre interuniversitaire de recherche sur la science et la technologie (CIRST-UQAM) Montreal "Lucid, focused, and rigorous ... An outstanding book that makes important contributions to intellectual history, the history of medicine, and their methodologies." -- -Jonathan Strauss Miami University

Read more less

Book SynopsisThis second edition of the popular advanced student textbook (previously published as Worms and Disease: A Manual of Medical Helminthology) has been thoroughly updated and revised since it was first published in 1975. It includes contributions and a chapter by Prof. Derek Wakelin, University of Nottingham, UK. An authoritative handbook covering all human helminth infections with particular emphasis on diagnosis, treatment, clinical manifestations, pathogenesis, epidemiology and control. Practical guidelines are given for estimating the clinical and public significance of helminthiases, vital in areas where the majority of inhabitants are infected with many helminths but only a few are sick.Table of Contents1: The Trematodes 2: The Cestodes 3: The Acanthocephalans 4: The Nematodes 5: Oher Groups 6: Immunology of Helminths 7: Epidemiological Aspects of Helminth Infections 8: Helminthological Techniques

Read more less

Book SynopsisDisease-related malnutrition is a global public health problem. The consequences of disease-related malnutrition are numerous, and include shorter survival rates, lower functional capacity, longer hospital stays, greater complication rates, and higher prescription rates. Nutritional support, in the form of oral nutritional supplements or tube feeding, has proven to lead to an improvement in patient outcome. This book is unique in that it draws together the results of numerous different studies that demonstrate the benefits of nutritional support and provides an evidence base for it. It also discusses the causes, consequences, and prevalence of disease-related malnutrition, and provides insights into the best possible use of enteral nutritional support.Table of Contents1: Scientific criteria for defining malnutrition 2: Prevalence of disease-related malnutrition 3: Causes of disease-related malnutrition 4: Consequences of disease-related malnutrition 5: Framework for establishing an evidence base for nutritional intervention 6: Evidence base for oral nutritional supplements 7: Evidence base for enteral tube feeding 8: Combined analysis of the effects of oral nutritional supplements and enteral tube feeding 9: Parenteral nutrition: a comparison with enteral tube feeding 10: Undertaking clinical nutrition intervention trials 11: Conclusions 12: Appendices 13: References

Read more less

Book SynopsisIsolation of Bacteriophages for Clinically Relevant Bacteria.- Observation of Bacteriophage Ultrastructure by Cryo-electron Microscopy.- Bacteriophage Taxonomy: A Continually Evolving Discipline.- Guidelines to Compose an Ideal Bacteriophage Cocktail.- Rapid Bench to Bedside Therapeutic Bacteriophage Production.- Bacteriophage Production in Compliance with Regulatory Requirements.- Nano/micro formulations for bacteriophage delivery.- Phage-Host Interaction Analysis using Flow Cytometry.- Bacteriophage control of infectious biofilms.- Studying bacteriophage efficacy using a zebrafish model.- Use of Galleria mellonella as an animal model for studying the antimicrobial activity of bacteriophages with potential use in phage therapy.- Interaction of Bacteriophages with the Immune System: Induction of Bacteriophage-specific Antibodies.- Bacteriophage Treatment of Infected Diabetic Foot Ulcers.- A Review of Phage Therapy for BonTable of Contents

Read more less

Book Synopsis

Read more less

Book SynopsisCough is the most familiar symptom of respiratory disease, and a problem which general practitioners must deal with on a daily basis. This timely volume draws together a wealth of recent research into the mechanisms, pharmacology and therapies for cough, and places these in clinical context. The text incorporates guidelines on the most common causes of cough, discusses treatments and pitfalls in management, summarizes current research on physiology, pharmacology and treatment of cough, and gives practical advice on diagnosis and management issues for the clinician. Cough: Causes, Mechanisms and Therapy is the most comprehensive, up-to-date account of the subject. It will update clinical and basic medical scientists, and promote future research. Readers are encouraged to implement the clinical implications of the discussion into routine practice. This volume will appeal to all those involved in the treatment of respiratory disease, particularly those in hospital Table of ContentsContributors. Preface. Section 1: Introduction. 1 The clinical and pathophysiological challenge of cough. 2 Epidemiology of cough. 3 A brief overview of the mechanisms of cough. Section 2: Cough in the clinic. 4 Clinical assessment of cough. 5 Measurement and assessment of cough. 6 Cough sensitivity: the use of provocation tests. 7 Causes, assessment and measurement of cough in children. 8 The quality of life in coughers Section 3: Clinical conditions with cough. 9 Cough in lower airway infections. 10 Cough in gastro-oesophageal reflux. 11 Cough in postnasal drip, rhinitis and rhinosinusitis. 12 Cough and airway hyperresponsiveness. 13 Cough in chronic obstructive pulmonary disease (COPD). 14 Cough in suppurative airway diseases. 15 Cough in cancer patients. . Section 4: Pathophysiology. 16 Sensory pathways for the cough reflex. 17 Neurogenesis of cough. 18 Plasticity of vagal afferent fibres mediating cough. 19 Motor mechanisms and the mechanics of cough. 20 Mucus hypersecretion and mucus clearance in cough. 21 Animal models of cough. Section 5: Therapy. 22 Mechanisms of actions of centrally acting antitussives - electrophysiological and neurochemical analysis. 23 Pharmacology of peripherally acting antitussives. 24 Current and potential future antitussive therapies. 25 Placebo effects of antitussive treatments on cough associated with acute upper respiratory tract infection. 26 Mucoactive agents for the treatment of cough. 27 Management of cough. Index

Read more less

Book SynopsisThe second edition of Syncope: Mechanisms and Management has been completely updated and revised and remains the most comprehensive textbook ever published on this common clinical entity. It provides up-to-date coverage of virtually every known cause of syncope, integrating knowledge of pathophysiology with practical guidelines for diagnosis and management. Incorporating clinical, investigative and experimental work conducted by leading authorities from all over the world, this book will serve as a practical resource for practicing cardiologists, electrophysiologists, neurologists, internists, pediatricians, and family physicians, as well as residents and fellows in these disciplines.Trade Review'The editors succeed in providing a comprehensive and up-to-date description of the broad scope of syncope, which makes this book a principal text in the field of syncope. The book is very well written and is an excellent addition to the library of any physician who seeks information on the causes, evaluation, and management of syncope.' Hamid Afshar (MD, Ochsner Clinic Foundation), DoodysTable of ContentsChapter 1: Syncope: An Overview of Evaluation and Management. Chapter 2: Neurocardiogenic Syncope. Chapter 3: Dysautonomic (Orthostatic) Syncope. Chapter 4: Bradyarrhythmias as a Cause of Syncope. Chapter 5: Tachyarrhythmias as a Cause of Syncope. Chapter 6: Use of Electrophysiologic Studies in Syncope: Practical Aspects of Diagnosis and Management. Chapter 7: Tilt Table Testing. Chapter 8: Use of Implantable Cardioverter Defibrillators in Patients With Syncope. Chapter 9: Neurologic Causes of Syncope. Chapter 10: Structural and Obstructive Causes of Cardiovascular Syncope. Chapter 11: Inherited Arrhythmic and Related Causes of Syncope. Chapter 12: Psychiatric Disorders in Patients With Syncope. Chapter 13: Postural Tachycardia, Orthostatic Intolerance and the Chronic Fatigue Syndrome. Chapter 14: Carotid Sinus Hypersensitivity. Chapter 15: Miscellaneous Causes of Syncope. Chapter 16: Syncope in the Child and Adolescent. Chapter 17: Syncope in the Athlete. Chapter 18: Syncope in the Elderly. Chapter 19: The Implantable Loop Recorder for Diagnosis of Unexplained Syncope. Chapter 20: Driving and Syncope. . Chapter 21: Syncope and the Law

Read more less

Book SynopsisThis brand new edition pulls together the most up-to-date information on this complex, multidisciplinary area in a practical, user-friendly manner. It deals with the important social and psychological aspects for palliative care of people with incurable diseases including quality of life, communication and bereavement issues.Table of ContentsContributors vi Foreword viii 1 The principles of palliative care 1Balfour Mount, Geoffrey Hanks, Lorna McGoldrick 2 The principles of control of cancer pain 4Marie Fallon, Geoffrey Hanks, Nathan Cherny 3 Difficult pain 8Lesley Colvin, Karen Forbes, Marie Fallon 4 Breathlessness, cough, and other respiratory problems 13Carol Davis, Gillian Percy 5 Oral health in patients with advanced disease 17Jeremy Bagg, Andrew Davies 6 Anorexia, cachexia, nutrition, and fatigue 21Kenneth Fearon, Matthew Barber 7 Nausea and vomiting 25Kathryn Mannix 8 Constipation, diarrhoea, and intestinal obstruction 29Nigel Sykes, Carla Ripamonti, Eduardo Bruera, Debra Gordon 9 Depression, anxiety, and confusion 36Mari Lloyd-Williams 10 Emergencies 40Stephen Falk, Colette Reid 11 The last 48 hours 44James Adam 12 Palliative care for children 48Ann Goldman 13 Communication 52David Jeffrey 14 The carers 56Julia Addington-Hall, Amanda Ramirez 15 Chronic non-malignant disease 59Marie Fallon, Joanna Chambers, Francis Dunn, Raymond Voltz, Gian Borasio, Rob George, Roger Woodruff 16 Community palliative care 68Keri Thomas 17 Bereavement 74Marilyn Relf 18 Complementary therapies 78Michelle Kohn, Jane Maher Index 83

Read more less

Book SynopsisObesity is a hugely expensive and increasing problem worldwide, leading to disability, reproductive problems, depression and accelerated metabolic and vascular diseases in a large proportion of men, women and children.Table of ContentsContributors vii Foreword ix 1 Obesity—time to wake up 1David Haslam, Naveed Sattar, Mike Lean 2 Assessment of obesity and its clinical implications 4Thang S Han, Naveed Sattar, Mike Lean 3 Management: Part I—Behaviour change, diet, and activity 8Alison Avenell, Naveed Sattar, Mike Lean 4 Management: Part II—Drugs 12Mike Lean, Nick Finer 5 Management: Part III—Surgery 16John G Kral 6 Strategies for preventing obesity 20Mike Lean, Jose Lara, James O Hill 7 Risk factors for diabetes and coronary heart disease 24Sarah H Wild, Christopher D Byrne 8 Obesity and vascular disease 27Debbie A Lawlor, Mike Lean, Naveed Sattar 9 Obesity and cancer 31Donald C McMillan, Naveed Sattar, Mike Lean, Colin S McArdle 10 Obesity and reproduction 34Jane E Ramsay, Ian Greer, Naveed Sattar 11 Childhood obesity 38John J Reilly, David Wilson 12 Obesity—can we turn the tide? 42Mike Lean, Laurence Gruer, George Alberti, Naveed Sattar Index 47

Read more less

Book SynopsisFainting, the sudden and often unpredictable loss of consciousness, can be a frightening experience. While often benign, fainting can sometimes be the sign of serious illness. Recurrent fainting can significantly disrupt a person's life, and make them prone to injury and, on occasion, death. The Fainting Phenomenon, Second Edition is a valuable information resource for anyone whose life is affected by fainting. Written for the layperson, this book will help you: Understand the different reasons why people faint and their significance Seek proper medical attention and treatment Deal with related conditions such as Postural Tachycardia Syndrome and Orthostatic Hypertension This is an indispensable and reassuring guide for parents, families and care givers.Trade Review"This book would be a very useful introductory text for medical students and nurses to read … .A useful size and covers theory to an appropriate depth." (Cardiology News, October - November 2007) Review of edition 1: This book is packed with information in ‘layman’s terms’ – @we ordinary (non-medical) people’ can then start to understand different types of faints that are being experienced or witnessed. The book can get very technical in parts, but not overly, regarding the heart, brain and systems. The Fainting Phenomenon book by Blair Grub should be in every surgery in the UK, it is a must that every Dr should have to hand. This is also a very good book for anyone who faints, be they patient, parents or carers, it will set them off on the road to ask the right questions with medical people to obtain a diagnosis for faints to put people (old or young) who suffer from this phenomenon at ease. It is a must read and should be a best seller in every UK surgery and hospital!Table of Contents1 Introduction.. 2 The Fainting Phenomenon.. 3 The Normal Nervous System.. 4 The Normal Cardiovascular System.. 5 Orthostatic Intolerance and Orthostatic (postural) Hypotension.. 6 Neurocardiogenic Syncope.. 7 Postural Tachycardia Syndrome and Chronic Fatigue Syndrome.. 8 Other Possible Causes of Fainting.. 9 Fainting in Children and Adolescents and in Older People.. 10 Diagnosing the Underlying Causes of Fainting.. 11 Treating Fainting.. 12 Wrapping Up. Glossary of useful terms. Index.

Read more less

Book SynopsisThe importance of appropriate and effective management of patient with long term chronic conditions cannot be underestimated.Case Management of Long-Term Conditions aims to provide all appropriate practitioners (including nurses, pharmacists, physiotherapists, andsocial care practitioners) who might be involved in delivery of proactive case management with a practical understanding of how their knowledge and skills can be utilised to improve outcomes for people with chronic long-term conditions. The text contains some broad reflections on care and service delivery based on reviews of evidence and views from clinicians in the use of these skills and competencies to deliver improved outcomes for clients.Table of ContentsIntroductionix 1 Background to the Implementation of Case Management Models for Chronic Long-Term Conditions within the National Health Service 1 Introduction 1 Primary care management of long-term conditions 2 How management approaches have been developed 3 Developing and delivering care 4 Future of care 5 The impact and cost of chronic disease 6 Identifying patients who require case management 7 National guidelines and evidence-based practice 8 Embedding evidence in practice 8 Making progress in the management of chronic conditions 9 Modernising care in the National Health Service 10 Developing case management and care delivery 10 Case management in the National Health Service 11 Promotion of self-management and self-care 13 Partnerships and expectations 13 Conclusion 15 References 15 2 Case Management Models: Nationally and Internationally 18 Introduction 18 The context for case management in the NHS 20 Impact of managed care models 21 International models of care reviewed 22 The Alaskan Medical Service 22 Kaiser Permanente (North California) 24 Group Health Cooperative (Seattle, Washington) 25 HealthPartners (Minnesota) 25 Touchpoint Health Plan (Wisconsin) 26 Anthem Blue Cross and Blue Shield (Connecticut) 26 UnitedHealth Europe Evercare 26 Amsterdam HealthCare System (the Netherlands) 27 Outcome intervention model (New Zealand) 28 National model of chronic disease prevention and control (Australia) 28 Guided Care (United States) 28 PACE (United States) 28 Veterans Affairs (Unites States) 29 Improving Chronic Illness Care (Seattle) 29 Expanded Chronic Care Model (Canada) 29 Pfizer (United States) 29 Green Ribbon Health: Medicare in health support (Florida) 30 What do these models provide? 30 Models in use in England 30 Care management in social care 32 Case management models in the NHS 32 Joint NHS and social care 36 Data for case management 38 Evaluation 38 Conclusion 40 References 41 3 Competencies for Managing Long-Term Conditions 43 Introduction 43 Development of the competency framework 44 What the competencies are expected to deliver 46 The competencies: what are they? 46 Domain A: advanced clinical nursing practice 47 Domain B: leading complex care co-ordination 49 Domain C: proactively manage complex long-term conditions 52 Domain D: managing cognitive impairment and mental well-being 52 Domain E: supporting self-care, self-management and enabling independence 55 Domain F: professional practice and leadership 57 Domain G: identifying high-risk people, promoting health and preventing ill health 58 Domain H: end-of-life care 59 Domain I: interagency and partnership working 60 What the competencies aim to do 61 Developing educational models to develop competencies 62 Conclusion 64 References 64 4 Outcomes for Patients – Managing Complex Care 66 Introduction 66 The areas of competence and deliverables for patients: Leading complex care co-ordination 66 Identifying high-risk patients, promoting health and preventing ill health 74 Interagency and partnership working 77 Conclusion 82 References 82 5 Outcomes for Patients – Advanced Nursing Practice 85 Introduction 85 Advanced clinical nursing practice 85 Proactively manage complex long-term conditions 91 Professional practice and leadership 94 Managing care at the end of life 97 Conclusion 101 References 102 6 Outcomes of Case Management for Social Care and Older People 105 Introduction 105 Policy drivers for the care of older people 105 Health and social care integration 108 Cost of care for older people 109 What do people expect in old age and how will these services be commissioned? 111 What does case management offer to older people? 112 Integrated models of care 114 Impact of case management on older people 114 Managing resources 118 Outcomes for older people 118 Conclusions 119 References 120 7 Outcomes for Patients – Cancer Care and End-of-Life Care 123 Introduction 123 Gold Standards Framework for Palliative Care 125 Integrated Cancer Care Programme 125 Preparing for the pilot programmes 127 Delivering the pilots 129 Programme outcomes 130 Case Management and ICCP 131 Case management competencies – what can/should patients expect? 132 The real need for competencies 137 Advanced care planning 139 Preferred place of care and delivering choice programmes 140 Conclusion 140 References 142 8 Leadership and Advancing Practice 144 Introduction 144 What is leadership? 144 What does leadership provide? 145 Leadership framework in the NHS 146 Skills in leadership 147 Political understanding and functioning 148 Setting targets and delivering outcomes 148 Empowerment and influencing 149 Levels of competence 150 Other leadership frameworks 150 What does good leadership do? 153 Impact on organisations 153 Leadership in case management 154 Leadership and change 155 Leadership is in every role 156 Advanced practice 157 Prescribing 158 Advanced practice in long-term conditions 159 Conclusions 160 References 161 9 Self-Care and Patient Outcomes 164 Introduction 164 What is self-care? 164 Self-care and practitioners 167 Systems for self-care 168 Expert Patient Programme 168 Effectiveness of self-care programmes 169 Promoting self-care: staff role 170 Self-care: models 171 Self-care: the evidence base 173 Using information and technology for self-care 175 How do we engage patients in self-care? 179 Conclusions 180 References 183 10 What Does This Mean for Patients? 185 Introduction 185 Government expectations 186 What do patients want from care? 186 Reported outcomes from management of long-term conditions 187 Modernisation to enable outcomes for users of services 188 Do patients really see improvement? 188 Understanding the patient experience, how we find out? 190 Public Service Agreement targets 192 Other assessments of user/patient experiences 192 Patient-centred care 195 Allowing patients to tell their tale 195 Outcomes of care and patient experience 195 Experience in case management 197 Partnerships with patients: impact on experience 199 Quality for patients 200 Impact of the provision of information on patients’ views and outcomes 201 Conclusions 201 References 203 Index 207

Read more less

Book SynopsisThe remarkable story of how a large public-private partnership worked to control and defeat riverblindnessa scourge which had devastated rural communities and impeded socioeconomic development throughout much of Sub-Saharan Africa for generations. Riverblindness (onchocerciasis)a pervasive neglected disease, transmitted by the blackfly, that causes horrific itching, disfigurement, and loss of visionis also known as lion's stare in reference to the fixed, lifeless glare of the eyes blinded by the disease. The disease has destroyed countless lives for generations, particularly in Africa. Its effects are so devastating that the areas where it is most common (large expanses of land around rivers where the fly breeds) end up abandoned as villages move farther and farther away to more arid environments in order to escape the fly-biting, and hence the disease. The disease devastates communities from multiple angles: a large portion of each stricken community's population is disabled, often Table of ContentsForeword, by James D. WolfensohnPrefaceAcknowledgmentsChapter 1. The ChallengeChapter 2. Launching and Scaling Up the Onchocerciasis Control Program Chapter 3. Expansion and RescueChapter 4. The Game Changer—IvermectinChapter 5. Getting Mectizan to Africa, Concluding the OCPChapter 6. A Closer Look at Socioeconomic DevelopmentChapter 7. Widening the Effort to All of AfricaChapter 8. Deepening and Widening the ObjectiveChapter 9. Learning from the Past, Looking to the FuturePeople InterviewedAcronyms and AbbreviationsNotesBibliographyIndex

Read more less

Book SynopsisThe Metabolic Syndrome is a valuable reference text, covering all aspects of the metabolic syndrome and its constituent diseases including inflammation, oxidation and adipocytokines. This book explains the aetiology, pathogenesis and clinical treatment of all risk factors as well as the relationship with diabetes, non alcoholic fatty liver disease, polycystic ovary syndrome and coronary heart disease. The Metabolic Syndrome has been further improved from the 1st edition that was highly commended in 2006 Annual British Medical Association medical books competition. All chapters from the first edition are fully updated and this new edition contains an increase in international contributions and five new chapters on: Childhood obesity and metabolic syndrome Bariatric surgery for obesity Fitness Brain insulin resistance and appetite The nature of the insulin resistance seen in metabolic syTrade Review"It's rare to find an academic book as engaging as this one. While clearly focused on a specific disease entity, the magnitude of the metabolic disease epidemic coupled with the comprehensive review of the topic this book delivers, should make it interesting reading to a diverse audience." (Doody's, 3 February 2012) "This excellent book must be considered the flagship text in the Wiley series encompassing obesity, diabetes and insulin resistance." (Practical Diabetes, 2011) "In all, the text provides a valuable summary of current knowledge, and it may even convince doubters of the existence of the metabolic syndrome! The information that is provided will be of considerable interest to both applied scientists and clinicians who study and treat the epidemics of physical inactivity and obesity that currently afflict so many countries." (Faculty of Physical Education & Health, 2011) Table of ContentsList of Contributors vii Foreword, Professor Sir George Alberti xi Preface xiii 1 The Epidemiology of the Metabolic Syndrome and its Association with Diabetes, Cardiovascular Disease and Other Conditions 1Sarah H. Wild and Christopher D. Byrne 2 Metabolic Syndrome and Ethnicity 19Therese Tillin and Nita G. Forouhi 3 Developmental Origins of Endothelial Dysfunction: a Key Step in Cardiometabolic Disease 45Christopher Torrens, Geraldine F. Clough and Mark A. Hanson 4 Developmental Origins of Insulin Resistance and Type 2 Diabetes 60Susan E. Ozanne and Kenneth Siddle 5 The Metabolic Syndrome in Childhood 81Ram Weiss and Sonia Caprio 6 Assessment of Insulin Sensitivity 88Julia Szendroedi, Esther Phielix and Michael Roden 7 Recent Progress in Identifying Genes Contributing to Type 2 Diabetes and Metabolic Syndrome 106Weijia Xie, Timothy M. Frayling and Michael N. Weedon 8 Endocrine Aspects of the Metabolic Syndrome 120Richard I.G. Holt and Peter H. Sönksen 9 Brain Insulin Resistance 139Katharine F. Hunt, Yee Seun Cheah and Stephanie A. Amiel 10 Cardiorespiratory Fitness and the Metabolic Syndrome 165Paul A. McAuley and Steven N. Blair 11 Metabolic Syndrome and Mental Illness 177Richard I.G. Holt and Robert C. Peveler 12 Atherothrombosis and the Metabolic Syndrome 194Kristina F. Standeven and Peter J. Grant 13 Inflammation and Metabolic Syndrome 210Sridevi Devaraj, David Siegel and Ishwarlal Jialal 14 Adipocytokine Dysregulation, Obesity and the Metabolic Syndrome 229Ulf Smith and Xiaolin Yang 15 Non-Alcoholic Fatty Liver Disease 245Mohamed H. Ahmed and Christopher D. Byrne 16 Polycystic Ovary Syndrome 278Naveed Sattar 17 Nutrition: Its Relevance in Development and Treatment of the Metabolic Syndrome 297Lisa Te Morenga and Jim Mann 18 Treatments for the Metabolic Syndrome 327Markolf Hanefeld, Ulrike Schatz and Frank Schaper 19 Metabolic/Bariatric Surgery Therapy for the Metabolic Syndrome 347Henry Buchwald Index 357

Read more less

Book SynopsisI. Concepts & Methods.- 1.Concepts in Viral Disease Epidemiology & Control.- 2.Virologic Detection & Characterization.- 3.Immunologic Detection & Characterization.- 4.Surveillance & Epidemiologic Investigation.- 5.Viral Dynamics & Mathematical Models.- II. Viruses Causing Acute Syndromes.- 6.Adenoviruses.- 7.Alphaviruses:Equine Encephalitis & Others.- 8.Arenaviruses:Lassa Fever, Lymphocytic Choriomeningitis & Others.- 9.Bunyaviruses:Hantavirus & Others.- 10.Coronaviruses: Severe Acute Respiratory Syndrome & Others.- 11.Enteroviruses &Parechoviruses: Echoviruses, Coxsackieviruses, & Others.- 12.Enteroviruses:Enterovirus 71.- 13.Enteroviruses:Polio.- 14.Filoviruses: Marburg & Ebola.- 15.Flaviviruses: Dengue.- 16.Flaviviruses: Yellow Fever, Japanese B, West Nile & Others.- 17.Hepatitis A Virus.- 18.Hepatitis E Virus.- 19.Influenza Viruses.- 20.Noroviruses, Sapoviruses, & Astroviruses.- 21.Orthopoxviruses: Variola, Vaccinia, Cowpox & Monkeypox.- 22.Paramyxoviruses: Henipaviruses.- 23.Paramyxoviruses: Measles.- 24.Paramyxoviruses: Mumps.- 25.Paramyxoviruses Parainfluenza Virus.- 26.Paramyxoviruses: Respiratory Syncytial Virus & Metapneumovirus.- 27. Parvoviruses.- 28.Rhabdovirus: Rabies.- 29. Rhinoviruses: Colds.- 30. Rotaviruses.- 31. Rubella Virus.-III. Viruses Causing Acute & Chronic Syndromes &/or Malignancy.- 32. Hepatitis viruses: Hepatitis B & Hepatitis D.- 33.Hepatitis viruses: Hepatitis C.- 34. Hepatitis viruses: Hepatocellular Carcinoma.- 35. Human Herpesviruses: Cytomegalovirus.- 36.Human Herpesviruses: Herpes Simplex Types 1 & 2.- 37.Human Herpesvirus: Human Herpesvirus 6.- 38.Human Herpesviruses: Infectious Mononucleosis & Other Non-Malignant Diseases.- 39.Human Herpesviruses: Kaposi Sarcoma & Other Malignancies.- 40.Human Herpesviruses: Malignant Lymphoma.- 41.Human Herpesviruses: Nasopharyngeal Carcinoma & Other EpithelialTumors.- 42.Human Herpesviruses: Varicella & Zoster.- 43.Human Immunodeficiency Viruses Types 1 & 2.- 44.Human Papillomaviruses: Cervical Cancer & Warts.- 45.Human T Cell Leukemia Viruses Types 1 & 2.- 46.Polyomaviruses: Progressive Multifocal Leukoencephalopathy & Other Diseases.- IV Other Transmissible Agents.- 47.Prions & Transmissible Spongiform Encephalopathy.Table of ContentsI. Concepts & Methods.- 1.Concepts in Viral Disease Epidemiology & Control.- 2.Virologic Detection & Characterization.- 3.Immunologic Detection & Characterization.- 4.Surveillance & Epidemiologic Investigation.- 5.Viral Dynamics & Mathematical Models.- II. Viruses Causing Acute Syndromes.- 6.Adenoviruses.- 7.Alphaviruses:Equine Encephalitis & Others.- 8.Arenaviruses:Lassa Fever, Lymphocytic Choriomeningitis & Others.- 9.Bunyaviruses: Hantavirus & Others.- 10.Coronaviruses: Severe Acute Respiratory Syndrome & Others.- 11.Enteroviruses & Parechoviruses: Echoviruses, Coxsackieviruses, & Others.- 12.Enteroviruses:Enterovirus 71.- 13.Enteroviruses:Polio.- 14.Filoviruses: Marburg & Ebola.- 15.Flaviviruses: Dengue.- 16.Flaviviruses: Yellow Fever, Japanese B, West Nile & Others.- 17.Hepatitis A Virus.- 18.Hepatitis E Virus.- 19.Influenza Viruses.- 20.Noroviruses, Sapoviruses, & Astroviruses.- 21.Orthopoxviruses: Variola, Vaccinia, Cowpox & Monkeypox.- 22.Paramyxoviruses: Henipaviruses.- 23.Paramyxoviruses: Measles.- 24.Paramyxoviruses: Mumps.- 25.Paramyxoviruses Parainfluenza Virus.- 26.Paramyxoviruses: Respiratory Syncytial Virus & Metapneumovirus.- 27. Parvoviruses.- 28.Rhabdovirus: Rabies.- 29. Rhinoviruses: Colds.- 30. Rotaviruses.- 31. Rubella Virus.- III. Viruses Causing Acute & Chronic Syndromes &/or Malignancy.- 32. Hepatitis viruses: Hepatitis B & Hepatitis D.- 33.Hepatitis viruses: Hepatitis C.- 34. Hepatitis viruses: Hepatocellular Carcinoma.- 35. Human Herpesviruses: Cytomegalovirus.- 36.Human Herpesviruses: Herpes Simplex Types 1 & 2.- 37.Human Herpesvirus: Human Herpesvirus 6.- 38.Human Herpesviruses: Infectious Mononucleosis & Other Non-Malignant Diseases.- 39.Human Herpesviruses: Kaposi Sarcoma & Other Malignancies.- 40.Human Herpesviruses: Malignant Lymphoma.- 41.Human Herpesviruses: Nasopharyngeal Carcinoma & Other Epithelial Tumors.- 42.Human Herpesviruses: Varicella & Zoster.- 43.Human Immunodeficiency Viruses Types 1 & 2.- 44.Human Papillomaviruses: Cervical Cancer & Warts.- 45.Human T Cell Leukemia Viruses Types 1 & 2.- 46.Polyomaviruses: Progressive Multifocal Leukoencephalopathy & Other Diseases.- IV Other Transmissible Agents.- 47.Prions & Transmissible Spongiform Encephalopathy.

Read more less

Book SynopsisMargaret Pollak explores experiences, understandings, and care of diabetes in a Native urban community in Chicago made up of individuals representing more than one hundred tribes from across the United States and Canada.Trade Review"Pollak's book is an important and valuable addition to medical historiography. It will be beneficial to a wide audience in the field of history as well as for medical professionals and clinicians. The use of oral history is important in a study like this to give voice to those who have been previously hidden from history. The book is extremely well written and has an excellent flow. It was an enjoyable read and covers a fascinating scope."—Lauren Young, H-Sci-Med-Tech"Drawing on extensive ethnographic interviews, observations, informal conversations, surveys, and field literature, Pollak offers a rich exploration of indigenous Chicagoans' experiences, care, and cultural understandings, noting how diabetes shapes beliefs and practices among those living with the disease and care providers. The study concludes by broadly examining historical and contemporary factors that led to the ongoing epidemic, and subsequently formulated indigenous lay perceptions of illness and health, and how that knowledge may be incorporated into the health-care system to strengthen outcomes, making this book an important contribution."—G. R. Campbell, Choice“The interdisciplinary approach to this subject makes an important contribution not only to medical anthropology and Native American studies but also to public health, medical humanities, American studies, and cultural studies. Pollak deftly and simply lays out the discursive turns of biomedical explanations about diabetes within historical context and also demonstrates the structural injustices that complicate biomedical interventions.”—Sandra L. Garner, author of To Come to a Better Understanding: Medicine Men and Clergy Meetings on the Rosebud Reservation, 1973–1978Table of ContentsList of Tables Acknowledgments Introduction 1. The Building of Chicago’s Contemporary Indigenous American Population 2. Native Chicago 3. Diabetes among Indigenous Americans 4. Diabetes in Native Chicago 5. Local Understandings and Explanations of Diabetes 6. Care in the Context of Chronicity Conclusion Appendix 1: Interview Participants Appendix 2: Sample Questions Appendix 3: Research Approval Notes Bibliography Index

Read more less

Book SynopsisTrade ReviewA very readable introduction to a fascinating subject and a valuable example of the importance of studying the Byzantine origins of medieval institutions. * Church History *This is a compact, accessible study, which delivers on its promise to bring the insights provided by studies of late antique Greek leprosy to bear on medieval Latin ones. * History of Religions *A welcome resource for the teaching of medieval leprosy, a fraught and fascinating topic in undergraduate classrooms. Walking Corpses both expands the field of study and shows directions in which this necessary endeavor can be continued. * Comitatus *

Read more less

Book SynopsisThe influenza epidemic of 1918 was one of the worst medical disasters in human history, taking close to thirty million lives worldwide in less than a year, including more than 500,000 in the United States. What made this pandemic even more frightening was the fact that it occurred when death rates for most common infectious diseases were diminishing. Still, an epidemic is not merely a medical crisis; it has sociological, psychological, and political dimensions as well. In Influenza and Inequality, Patricia J. Fanning examines these other dimensions and brings to life this terrible episode of epidemic disease by tracing its path through the town of Norwood, Massachusetts. By 1918, Norwood was a small, ethnically diverse, industrialized, and stratified community. Ink, printing, and tanning factories were owned by wealthy families who lived privileged lives. These industries attracted immigrant laborers who made their homes in several ethnic neighborhoods and endured prejudice and discrimination at the hands of native residents. When the epidemic struck, the immigrant neighborhoods were most affected; a fact that played a significant role in the town's response--with tragic results. This close analysis of one town's struggle illuminates how even well-intentioned elite groups may adopt and implement strategies that can exacerbate rather than relieve a medical crisis. It is a cautionary tale that demonstrates how social behavior can be a fundamental predictor of the epidemic curve, a community's response to crisis, and the consequences of those actions.

Read more less

Book SynopsisThis volume presents two meeting reports from recent scientific conferences and a third paper of draft consensus guidelines for treating Shwachman-Diamond syndrome. The first meeting report, "Advances in Bipolar Disorder: Selected Sessions from the International Conference on Bipolar Disorder," covers the 9th International Conference on Bipolar Disorder (ICBD) held in Pittsburgh, PA, June 9–11, 2011. The conference focused on a number of important issues concerning the diagnosis of bipolar disorders across the life span, advances in neuroscience, treatment strategies for bipolar disorders, early intervention, and medical comorbidity. This meeting report presents key points from the sessions including: strategies for moving biology forward; bipolar disorder and the forthcoming new DSM-5 nomenclature; management of bipolar disorders—both theory and intervention, with an emphasis on the medical comorbidities; and a review of several key task force reports commissioned by the International Society for Bipolar Disorder (ISBD). The second meeting report covers the Sixth International Congress on Shwachman-Diamond Syndrome (SDS), the only multidisciplinary forum devoted specifically to SDS, held at the New York Academy of Sciences June 28–30, 2011. SDS is an autosomal recessive genetic disorder involving multiple organ systems and affecting children and young adults. The meeting report explores the most important recent advances in our understanding of the clinical features, current management, and treatment of SDS, and the molecular function of SBDS in hematopoiesis, leukemogenesis, and organogenesis. The third paper in this volume presents draft consensus guidelines for diagnosis, evaluation, and treatment of Shwachman-Diamond syndrome. Evidence-based conclusions were made whenever possible. However, as in other rare diseases, the data are often anecdotal. Therefore, recommendations were also based upon the consensus of experienced clinicians from Canada, Europe, and the United States during and following an international SDS conference. New recommendations regarding diagnosis and management have been made reflecting advances in understanding the genetic basis and clinical manifestations of the disease. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Read more less

Book SynopsisThis volume is the eleventh published from a conference sponsored by the World Organization for Specialized Studies on Diseases of the Esophagus (OESO) and the second to be published in Annals. As with the preceding publications, the present one follows a world conference of OESO; in this case, a conference entitled “Reflux disease, from LES to UES, and beyond,” held in Como, Italy. Collectively, the papers present the wealth of ideas and knowledge covered by the four-day OESO conference on esophagology, with each paper showcasing the responses provided by top experts to precise questions during the sessions of the conference. NOTE: Annals volumes are available for sale as individual books or as a journal. For more information on institutional journal subscriptions, please visit: http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632 ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information on becoming a member.

Read more less

Book SynopsisRubella and rubeola were once commonly thought of as childhood diseases. In the last few decades, these illnesses have been largely brought under control in developed nations through widespread vaccinations. In developing areas, however, these viral infections still pose a threat to children and adults alike. Although both diseases are known commonly as the measles, the viruses that cause them are not closely related. ""German measles"" (rubella) is caused rubivirus, and the red measles (rubeola) is caused by morbilivirus. ""Rubella and Rubeola"" takes a look at the history, pathology, potential complications, prevention, and treatment of these diseases.The chapters include: An Ancient Plague; Viral Diseases; Rubeola: The Red Measles; Rubella: The ""German Measles""; Epidemiology; and, Diagnosis, Treatment, and Prevention.

Read more less

Book SynopsisIn 1929, Lemuel Whitley Diggs arrived in Memphis as a newly minted physician from the Johns Hopkins University School of Medicine. Rather than establish a private practice, which would have been a lucrative endeavor in a modern city such as Memphis, Diggs took a position as one of the first full-time faculty members with the University of Tennessee Medical Units, a position that afforded Diggs access to both patient care and clinical research, and a decision that would later define his career. As part of his position, Diggs saw patients at the Memphis City Hospital, a poor, inner-city facility constrained by Jim Crow laws and racial bias. He immediately recognized a high rate of sickle cell disease among his patients, a disease Diggs had been taught was rare and one laden with negative racial attributes. Diggs’s study of sickle cell disease would lead him to confront medical racism, establish the South’s first blood blank and the nation’s first sickle cell center, and help define the mission of St. Jude Children’s Research Hospital.Essentially a biography of Diggs, Blood Picture relates the life of a physician and intellectual with strong convictions and medically forward thinking. Diggs’s career spanned the Great Depression, World War II, and the civil rights movement, and he pushed the limits of medicine and sicklecell research in times of turbulent social change. His life reveals the consciousness of the South as seen through the profession he admired and loved.

Read more less

Book SynopsisCovers diseases, disorders, treatments, procedures, specialties, biology, and issues in an easy-to-use A-Z format, with sidebars addressing recent developments in medicine and concise information boxes for all diseases and disorders. In addition to completely new essays in this edition, all entries from the previous edition have been evaluated and updated by a panel of Medical Editors to ensure their currency and accuracy.

Read more less

Book SynopsisLow and middle income countries in Africa, Asia and Latin America bear a significant proportion of the global burden of chronic non-communicable diseases. This book synthesizes evidence across countries that share similar socio-economic, developmental and public health profiles, including rapid urbanization, globalization and poverty. Providing insights on successful and sustainable interventions and policies, it shows how to slow and reverse the rising burden of chronic diseases in resource-poor settings.Table of ContentsIntroduction: Addressing the chronic non-communicable disease burden in low and middle-income countries 1: Cardiovascular Diseases and diabetes in low and middle income countries 2: A review of cancers in Africa 3: Chronic non-communicable diseases and infectious diseases 4: Ageing and neurodegenerative diseases in low and middle income countries 5: Chronic non-communicable diseases and mental health disorders in Africa 6: Health systems and chronic non-communicable diseases in low and middle income countries 7: Population Surveillance and chronic non-communicable diseases 8: Community-based interventions for preventing chronic non-communicable diseases in low and middle income countries 9: Self-help and chronic non-communicable disease care: a preliminary review of existing models in low and middle income countries 10: Prevention and control of chronic non-communicable diseases: lessons from infectious diseases control 11: Prevention and control of chronic non-communicable diseases: lessons from high income countries 12: The global response for prevention and control of chronic non-communicable diseases: key milestones and outcomes

Read more less

Book SynopsisThis book aims to redefine the requirements of an effective care for the chronic diseases, and their difficulties of implementation; to analyze the processes allowing to reinforce quality and to contain the costs and the expenditure related to this care; and to release the dynamic processes of development of an efficient care, the organisational forms and the corresponding strategies.Table of ContentsAcknowledgements ix Introduction xi Chapter 1 The Challenge of Chronic Diseases 1 1.1 Chronic diseases 1 1.1.1 The burden of chronic diseases 1 1.1.2 Characteristics of chronic diseases 3 1.1.3 The case of type 2 diabetes 6 1.2 Management of chronic diseases 8 1.2.1 Complex care 8 1.2.2 Characteristics of effective care 8 1.3. Organization of the health system and coordination 11 1.3.1 Organizational imbalance of the health sector 11 1.3.2 Low coordination capacities 12 1.3.3 Coordination 14 Chapter 2 Some Alternative Schemes for the Management of Chronic Diseases 17 2.1. Cooperation systems at the initiative of professionals 17 2.1.1 Care and health network 17 2.1.2 A cooperative network 18 2.1.3 Multiprofessional health home 20 2.1.4 Care teams 21 2.2 Cooperation systems at the initiative of insurers 23 2.3 Chronic care model 25 Chapter 3 Difficulties in Implementing Effective Management 29 3.1 Technical difficulties 29 3.1.1 The nature of the information 29 3.1.2 Communication processes 31 3.2 Social difficulties 32 3.2.1 Influence as a promotion means in the interest of actors 32 3.2.2 Collaboration as a threat to actors’ autonomy 33 3.2.3 Collaboration as an opportunity 35 3.3 Cultural difficulties 36 Chapter 4 Redefining Conditions for the Effective Management of Chronic Diseases 41 4.1 Quality of the activities involved in the patients’ management 41 4.1.1 Quality as an attribute of actors 41 4.1.2 Quality as balance between care abilities and requirements 42 4.2 Diversity and relevance of the range of care, services and skills that can be mobilized 44 4.3 Cooperation of actors and coordination of their interventions 47 4.3.1 Cooperation between actors 47 4.3.2 Intervention coordination for chronic disease management 48 Chapter 5 Activities Specific to an Effective Management of Chronic Diseases 53 5.1 Nature of specific activities 53 5.1.1 Specific activities linked to the quality of procedures 54 5.1.2 Specific activities linked to the range of care and services that can be mobilized 55 5.1.3 Specific activities linked to cooperation and coordination 56 5.2 Implementation and funding of specific activities 57 5.2.1 Implementation problems of specific activities 57 5.2.2 Funding of specific activities 57 Chapter 6 Dynamic Processes for the Provision of Efficient Care 59 6.1 Deadlock and efficiency 59 6.2 Care quality and costs 62 6.3 System size and costs 64 6.4 Funding of a collective system and fee-for-service 67 Chapter 7 Lump Sum Funding, Efficiency and Development 71 7.1 Different lump sum funding methods 71 7.1.1 Budget 71 7.1.2 Capitation 73 7.1.3 Overall capitation 75 7.2 Overall capitation and development 76 7.3 Endogenous development limits 78 Chapter 8 An Illustration 83 8.1 Presentation of the care network 83 8.2 Analysis of RSD operation and development 87 8.2.1 Cost reduction 88 8.2.2 Size increase 90 8.3 Illustration scope and limits 90 8.3.1 Point of the illustration 91 8.3.2 Illustration limits 93 Chapter 9 From Processes to Organizational Structures 97 9.1 An organized system 97 9.1.1 Differentiation 97 9.1.2 Coordination 99 9.2 Coordination practices 101 9.3 Steering function 104 Chapter 10 Contractual Relationship Configurations 107 10.1 Structuring relationships 107 10.1.1 Orderly coordination relationships 107 10.1.2 Complex coordination relationships 109 10.1.3 Contractual relationships 111 10.2 Organizational configuration 113 10.2.1 A structured field of action 113 10.2.2 Areas and authorities 114 10.2.3 Organizational dynamics 115 Chapter 11 Implementation Strategy 119 11.1 Two change concepts 119 11.1.1 Synoptic change 119 11.1.2 Strategic change 120 11.2 The success of a doomed reform 121 11.2.1 The 1991 British reform 121 11.2.2 A double dynamic 123 11.2.3 Determinants of the change dynamic 124 11.3 Strategy elements 125 11.3.1 Principles and action logic 126 11.3.2 Strategic management 129 11.3.3 Management authority 131 Chapter 12 IS in Health System Restructuring 135 12.1 The unbalanced organization of the health care system 135 12.1.1 An unsuitable organization 135 12.1.2 A dissociation movement 137 12.2 IS in the system organization development 138 12.2.1 Intermediary structures 138 12.2.2 Health operator model 139 12.3 Promoting IS 142 12.3.1 More or less effective measures 142 12.3.2 Structural obstacles to IS creation 144 12.3.3 Some principles for a reform 147 Bibliography 151 Index 159

Read more less

Book SynopsisAs this field of surgery evolves, the educational needs of nurses specialising in this area continue to grow. This innovative text, a collaboration between specialists in the UK and the USA, and the first textbook written specifically for nurses, covers these exciting developments and also examines those factors that are driving the changes in the range and delivery of services offered to patients with colorectal disease.Table of ContentsAnatomy and physiology of the colon, rectum and anus. Extended nursing practice. Investigation and examination of a patient with colorectal problems. Common anal conditions. Colorectal cancer. Inflammatory bowel disease. Familial adenomatous polyposis. Stomas. Diverticular disease. Constipation. Irritable bowel disease. Laparascopic colorectal surgery. Faecal incontinence. Sexually transmitted diseases and AIDS. Colorectal conditions in paediatric patients. Infectious collidities.

Read more less

Book SynopsisThis text provides speech and language therapists and language researchers with a state-of-the art review covering all aspects of speech and language development in individuals with Down syndrome. Written by leading experts in the field, it includes chapters on: the principles which should guide intervention; prelinguistic development; pragmatics and communication; literacy and language; augmentative communication; intervention with adolescents and adults; maintenance of skills for older adults; and a perspective on pertinent issues. Each chapter summarizes research and provides guidelines for effective interventions. This book should be a valuable guide to those working in the field who wish to be able to provide evidence-based interventions for individuals with Down syndrome and to contribute to their quality of life by improving their communication skills.Table of ContentsPreface v Jean A Rondal Contributors vii Chapter 1 Principles of language intervention 1 Jean A Rondal, Sue Buckley Chapter 2 Prelinguistic training 11 Jean A Rondal Chapter 3 Phonological working memory difficulty and related interventions 31 frances A Conners Chapter 4 Speech acquisition and approaches to intervention 49 Carol Stoel-Gammon Chapter 5 Lexical development and intervention 63 Carolyn B Mervis, Angela M Becerra Chapter 6 Morphosyntactic training and intervention 86 Jean A Rondal Chapter 7 Pragmatic development and communication training 98 Leonard Abbeduto, Yolanda Keller-Bell Chapter 8 Augmentative communication 116 Gaye Powell, John Clibbens Chapter 9 Literacy and language 132 Sue Buckley Chapter 10 Continues language intervention with adolescents and adults with down syndrome 154 Christine Jenkins Chapter 11 Maintenance training in older ages 166 Jean A Rondal Conclusion 184 Sue Buckley, Jean A Rondal Appendix 1: Major acquisitions in morphosyntactic development 188 Jean A Rondal Appendix 2: Bilingual and multilingual issues 195 Jean A Rondal Index 207

Read more less

Book SynopsisThis book describes and discusses the assessment and treatment techniques applied by Occupational Therapists (OTs) to sufferers from Multiple Sclerosis (MS).The text begins with basic information about MS and follows this with suggestions for assessment and treatment. Then the specific issues of work, fatigue, leisure, mobility and the home are considered in detail. The needs of people who reach the later stages of the disease are discussed, as are the needs and concerns specific to carers of those with MS. Contact details are provided for many of the services and agencies mentioned in the text. Insight into the impact of MS on people's lives is provided by individuals with MS.Table of ContentsMultiple Sclerosis. Assessment. Management. Work and Multiple sclerosis. Fatigue in Multiple Sclerosis. Leisure for People With Multiple sclerosis. Mobility for People With Multiple Sclerosis. Multiple Sclerosis and The Home. Continuing Care. Caring for People With Multiple Sclerosis. Contact Addresses. References. Index.

Read more less

Book SynopsisThe only complete, scientifically rigorous, fully integrated reference giving a wide ranging and in-depth perspective on cerebral palsy and related neurodevelopment disabilities. It considers all aspects of cerebral palsy from the causes to clinical problems and their implications for individuals. Leading scientists present the evidence on the role of pre-term birth, inflammation, hypoxia, endocrinological and other pathways. They explore opportunities for neuroprotection leading to clinical applications. An international team of experts provides clinicians and researchers with key information on the mechanisms underlying impairments in movement, development, cognition, communication, vision, feeding, behaviour, sexuality, and musculoskeletal deformities. They present a wide range of person-centred assessment approaches, including clinical evaluation, measurement scales, neuroimaging and gait analysis. The principles of multi-disciplinary management are presented, in terms of therapist intervention, medication and surgery. The perspective of the book spans the lifelong course of cerebral palsy, taking into account worldwide differences in socio-economic and cultural factors. Many chapters are illustrated with clinical vignettes enabling direct translation into practice. Full integrated colour, with extensive cross-referencing make this a highly attractive and useful reference.Table of Contents1 Historical Perspective 2 Definition and Clinical Classification 3 Parenting a Child with Cerebral Palsy: Family and Social Issues 4 Personal Perspectives 5 Cerebral Palsy in Adulthood 6 Global Health Perspective 7 Brain Malformations 8 Perinatal Stroke 9 Pathways Involving Hypoxia-Ischaemia 10 Pathways Involving Bilirubin and other Brain-Injuring Agents 11 Maternal-Fetal Infection 12 Endocrine Pathways 13 Non-inflammatory and Non-endocrine Pathways from Prematurity to Cerebral Palsy 14 Neural Basis of Motor Control 15 Clinical Presentation 16 Neuroimaging 17 Clinical Neurophysiology 18 Orthopaedic Assessment 19 Motion Analysis 20 Intervention planning, implementation and evaluation 21 Enhancing activity and participation with assistive technology 22 Resources for people with cerebral palsy, parents, and families 23 Muscle Tone, Strength and Movement Disorders 24 Postural Control 25 Oromotor Function 26 Hand Function 27 Lower Limb Function 28 Cognition 29 Visual function 30 Hearing and Vestibular Function 31 Communication 32 Behaviour and Mental Health 33 Sleep 34 Epilepsy 35 Feeding and Nutrition 36 Respiratory Problems 37 Urinary function 38 Sexual Development, Sexual Health, Needs and Life experiences

Read more less

Book SynopsisThis book presents the latest evidence-based approaches to assessing and managing movement disorders in children. Uniquely, the authors have chosen to examine not just children with developmental coordination disorder, but also children with movement difficulties as a co-occurring secondary characteristic of another development disorder, including Attention Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, Specific language Impairment and Dyslexia. Guidelines are underpinned by motor learning theory, empiricism and professional practice. The authors have taken an ecological approach to management and show how professionals and carers working together can make relatively simple changes in a child's life that aggregate to substantial support. The book is rich in case studies to demonstrate the adaptability of these guidelines and show how they may be applied to children of different ages, abilities, and environments. The final chapter is comprised of interviews of thirteen notable clinicians and academics with intervention methodologies from around the world. This book is a valuable guide for anybody working with children with movement difficulties, including clinicians, teachers and parents.Table of ContentsNotable Clinicians Appointments ix Foreword xi Preface xiii 1 The nature of movement difficulties and developmental disorders 1 2 Principles from motor learning 32 3 Assessment and intervention 52 4 Assessment and other information: Case studies 72 5 From profiles through objectives to action 100 6 Specific intervention guideline 123 7 Case studies: Support and intervention 159 8 Interviews with notable clinicians and academics on intervention methodologies 190Anna Barnett, Reint H Geuze, Beth Hands, Sheila E Henderson, Amanda Kirby, Victoria McQuillan, Cheryl Missiuna, Motohide Myahara, Helene Polatajko, Mellissa Prunty, Bouwien Smits-Engelsman, Marina M Schoemaker and Peter Wilson 9 At a glance: Moving forward in the right direction 214 Index 221

Read more less

Book SynopsisCurrently, with so many commercial food companies selling ready-to-eat foods for the busy professional, nutrition science may be pushed to the wayside. For most of us, guidance is essential. This book is about the more logical and better substantiated nutritional practices and juried literature around the world, and its impact on health and disease. The monograph is appropriate for use in a nutritional or an epidemiology course as well as for anyone who wants to better their own nutritional choices, their health, or lower their risk for certain diseases.

Read more less

Book SynopsisThis book presents up-to-date, practically oriented information on major topics in acute hepatitis. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. The book opens by examining the local and global epidemiology of acute hepatitis. Detailed attention is then paid to each of acute hepatitis A, acute hepatitis B, acute hepatitis C, hepatitis D co-infection, and hepatitis E. Acute Hepatitis will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.Table of ContentsLocal and global epidemiology of acute hepatitis.- Acute hepatitis A.- Acute hepatitis B.- Acute hepatitis C.- Hepatitis D co-infection.- Hepatitis E.

Read more less

Book SynopsisThe textbook provides an overview of the sensory science field in the context of diseases such as obesity and Coronavirus disease 2019 (COVID-19). This book brings a summary of the state of the science in key areas and provides examples of translational science from using cellular and rodent models to human clinical trials and community health. The volume structure leads the reader through the physiology of taste and smell into how sensory testing for taste and smell is studied, basic mechanisms, various protocols that are used throughout the field along with the pros/cons of the current methods used. This resource is intended for classroom teaching, for novice researchers in sensory research as well as students and postdoctoral fellows. Example of courses are nutrition, basic nursing, interdisciplinary health courses, sensory perception (psychology), neuroscience, and medical courses, dentistry, food science and others. Table of ContentsTable of Contents 1. IntroductionDescription: Summary of the contents in the book and gaps identified Dr. Paule Joseph, National Institutes of Health Dr. Valerie Duffy, University of Connecticut Email: Valerie.duffy@uconn.edu and paule.joseph@nih.gov The biology/definition of chemical senses (Chapters 2-6)2. Taste and Smell Systems Development During Infancy and ChildhoodDescription: Provide an overview of taste and smell systems in development for humans primarily in childhood. Implications for development of feeding and eating behavioursDrs. Julie Mennella and Alissa Smethers, Monell Chemical Senses CenterEmail: mennella@monell.org 3. Anatomy, Physiology and Neurobiology of Olfaction and Gustation Description: The anatomy and physiology of olfaction and gustation, the neuromatrix will be reviewed. Neurobiology of taste and smell from the molecular level through the sensory science matrix is provided in the context of current evidence. Dr. Rosario Jaime- Lara & Dr. Paule Joseph, National Institutes of Health (NIH) Email: rosario.jaime-lara@nih.gov 4. Measurement of Olfaction: Screening and Assessment Description: Summary of how taste and smell is measured in human studies. Description of psychophysical methods and neuroimaging methods. Dr. Sanne Boesveldt, Wageningen University &ResearchDr. Valentina Parma, Temple University Email: valentina.parma@temple.edu 5. Measurements of Gustation: Screening and Assessment Description: Summary of how taste and smell is measured in human studies. Description of psychophysical methods and neuroimaging methods. State-of-the-science on smell and taste studies in large cohort studies. Dr. Valerie Duffy, University of Connecticut Email: Valerie.duffy@uconn.edu 6. Integration of Taste, Smell and Chemesthesis: Clinical Implications Description:Author: Dr. Brianne Linne & Dr. Christopher Simons- Ohio State University Email: simons.103@osu.edu The state-of-the-science on taste and olfaction (Chapter 7)7. Overview of Olfaction and Gustation under Metabolic InfluencesDescription: Recently published work and emerging research efforts have suggested that the olfactory and gustatory system is intimately linked with the endocrine systems that regulate or modify energy balance. This section will provide an overview of the state of the science Dr. Valerie Duffy, University of Connecticut and Dr. Paule Joseph, National. Institutes of Health Email: Valerie.duffy@uconn.edu and paule.joseph@nih.gov Disease cohorts (Chapters 8-12)8. Studies on the Sense of Smell and Taste in individuals with Obesity and Substance Use DisordersDescription: State-of-the-science of how obesity affects smell (olfaction) and taste (gustation)Dr. Carlotta Vizioli, Brianna Brooks Dr. Paule Joseph, National Institutes of Health Email: paule.joseph@nih.gov 9. Taste and Smell Alterations and Neurodegenerative Disorders Description: State-of-the-science of taste and smell disturbances in individuals with Alzheimer’s, Parkinson’s and dementia,Dr. Claire Murphy, San Diego State University Email: cmurphy@sdsu.edu 10. Studies on the Sense of Smell and Taste in individuals with Substance Use Disorders (SUD)Description: State-of-the-science of how SUD affects smell (olfaction) and taste (gustation)Dr. Khusbhu Agarwal, Christian McDuffie Dr. Paule Joseph, National Institutes of Health Email: paule.joseph@nih.gov 11. Taste and smell in Weight Loss Surgery Description: State-of-the-science of Taste and Smell Disturbances in Individuals undergoing bariatric surgery (weight loss surgery). Dr. Yanina Pepino, University of Illinois at Urbana-Champaign Email: ypepino@illinois.edu 12. Taste and Smell alterations and Cancer Therapies Description: State-of-the-science of taste and smell disturbances in cancer populations. Focus on current challenges and areas of future discovery.Dr. Alissa Nolden, UMass AmherstEmail: anolden@umass.edu 13. Oral Health and Chemosensory Problems Description: How clinicians specially dentist can assess chemosensory problemsDr. Miriam Grushka, William Osler Health System Toronto Email: miriamgrushka@gmail.com The future of the field (Chapter 13-14)14. Final Title to be Determined but the chapter will be focus on COVID-19 taste and smell loss Description: State-of-the-science on COVID-19, taste and smell loss Dr. Danielle Reed, Monell Chemical Senses Center Email: reed@monell.org 15. Oral Health and Microbiome: Implications for Taste Description: State-of-the-science on the role of oral health and emerging science of the microbiota and its implications for taste. Dr. Surkith Ganesan, University of Iowa Email: sukirth-ganesan@uiowa.edu

Read more less

Book SynopsisThis book critically reviews 75 important published papers that influence the practice of geriatric psychiatry. This book will assist anyone who is interested in the care of older adults with psychiatric disorders. It was written by thought leaders who shape the way geriatric psychiatry is currently practiced in the United States. All the major psychiatric disorders in later life are covered including anxiety disorders, bipolar disorders, depressive disorders, neurocognitive disorders, psychotic disorders, sleep disorders, and substance use disorders. It also reviews important studies on suicides in late life and interventional procedures in geriatric psychiatry like the ECT, and also evaluates the adverse effects of psychotropic medications on older adults with psychiatric disorders. The editors of the book along with input from members of the teaching and training committee of the American Association for Geriatric Psychiatry (AAGP) have chosen 75 published papers from the field of geriatric psychiatry that they believe provides the highest knowledge-yield/impact for practicing clinicians and educators in the field of geriatric mental health. The AAGP is a national association that represents and serves its members and the field of geriatric psychiatry. These 75 papers are critically appraised by the members of AAGP using a standardized format and a summary of these papers and their practical application is provided by these experts. This information can be used by anyone who wants to learn about the field of geriatric psychiatry.Table of ContentsSection 1: Adverse effects of medications.- Do atypical antipsychotics cause stroke?.- Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials.- Meta-analysis of the Impact of 9 Medication Classes on Falls in Elderly Persons.- The efficacy and safety of atypical antipsychotics for the treatment of dementia: a meta-analysis of randomized placebo-controlled trials.- Do antipsychotics lead to cognitive impairment in dementia? A meta-analysis of randomised placebo-controlled trials.- A Systematic Review and Meta-Analysis of the Risk of Dementia Associated with Benzodiazepine Use, After Controlling for Protopathic Bias.- Section 2: Anxiety Disorders.- Treatment of panic disorder in older adults: a pilot study comparison of alprazolam, imipramine, and placebo.- Efficacy and tolerability of citalopram in the treatment of late-life anxiety disorders: results from an 8-week randomized, placebo-controlled trial.- Efficacy and tolerability of duloxetine in elderly patients with generalized anxiety disorder: a pooled analysis of four randomized, double-blind, placebo-controlled studies.- Escitalopram for older adults with generalized anxiety disorder: a randomized controlled trial.- Meta-analysis Comparing Different Behavioral Treatments for Late-Life Anxiety.- Cognitive Behavior Therapy for Generalized Anxiety Disorder Among Older Adults in Primary Care: A Randomized Clinical Trial.- Stepped-care prevention of anxiety and depression in late life: a randomized controlled trial.- A randomized controlled study of paroxetine and cognitive-behavioural therapy for late-life panic disorder.- Antidepressant medication augmented with cognitive-behavioral therapy for generalized anxiety disorder in older adults.- A meta-analysis of cognitive functioning in older adults with PTSD.- Anxiety as a Predictor for Cognitive Decline and Dementia: A Systematic Review and Meta-Analysis.- Section 3: Bipolar Disorder.- A Pilot Study of Standardized Treatment in Geriatric Bipolar Disorder.- Differences in clinical features and mental health service use in bipolar disorder across the lifespan.- Effect of antidepressant use on admissions to hospital among elderly bipolar patients.- GERI-BD: A Randomized Double-Blind Controlled Trial of Lithium and Divalproex in the Treatment of Mania in Older Patients With Bipolar Disorder.- History of Bipolar disorder and the risk of dementia: A systematic review and meta-analysis.- Section 4. Delirium.- A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients.- Delirium in elderly patients and the risk of post discharge mortality, institutionalization, and dementia: a meta-analysis.- Effectiveness of multicomponent nonpharmacological delirium interventions: a meta-analysis.- Antipsychotic Medication for Prevention and Treatment of Delirium in Hospitalized Adults: A Systematic Review and Meta-Analysis.- Interventions for preventing delirium in older people in institutional long‐term care.- Section 5: Depressive Disorders.- Nortriptyline and Interpersonal Psychotherapy as Maintenance Therapies for Recurrent Major Depression. A Randomized Controlled Trial in Patients Older Than 59 Years.- Continuation treatment of delusional depression in older adults.- Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: a randomized controlled trial.- Remission in Depressed Geriatric Primary Care Patients: A Report from the PROSPECT Study.- Executive dysfunction and the course of geriatric depression.- Maintenance Treatment of Major Depression in Old Age.- Placebo-Controlled Study of Relapse Prevention With Risperidone Augmentation in Older Patients with Resistant Depression.- Efficacy of Second-Generation Antidepressants in Late-Life Depression: A Meta-Analysis of the Evidence.- A double-blind randomized controlled trial of olanzapine plus sertraline vs olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD).- Speed of remission in elderly patients with depression: electroconvulsive therapy v. medication.- A systematic review and meta-analysis of psychotherapy for late-life depression.- A novel strategy for continuation ECT in geriatric depression: phase 2 of the PRIDE Study.- Right Unilateral Ultrabrief Pulse ECT in Geriatric Depression: Phase 1 of the PRIDE Study.- Improvement in Depression is Associated with Improvement in Cognition in Late-Life Psychotic Depression.- Section 6: Electroconvulsive Therapy.- Continuation/Maintenance Treatment with Nortriptyline Versus Combined Nortriptyline and ECT in Late-Life Psychotic Depression: A Two-Year Randomized Study.- Safety and utility of acute electroconvulsive therapy for agitation and aggression in dementia.- Electroconvulsive therapy and risk of dementia in patients with affective disorders: a cohort study.- Electroconvulsive Therapy and Risk of Dementia-A Nationwide Cohort Study in Taiwan.- Section 7: Grief.- Treatment of complicated grief in elderly persons: a randomized clinical trial.- Section 8: Pain Disorders.- Association Between Psychological Interventions and Chronic Pain Outcomes in Older Adults: A Systematic Review and Meta-Analysis.- Section 9: Psychotic Disorders.- A Randomized, Controlled Trial of Cognitive Behavioral Social Skills Training for Middle-Aged and Older Outpatients with Chronic Schizophrenia.- Safety and tolerability of oral paliperidone extended-release tablets in elderly patients with schizophrenia: a double-blind, placebo-controlled study with six-month open-label extension.- Antipsychotic treatment for elderly people with late-onset schizophrenia.- Schizophrenia and risk of dementia: A meta-analysis study.- Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS): a randomised, controlled, double-blind trial.- Section 10: Neurocognitive Disorders.- Efficacy and safety of cholinesterase inhibitors in Alzheimer's disease: a meta-analysis.- Depression and risk for Alzheimer disease: Systematic review, Meta-analysis, and Metaregression analysis.- Effectiveness of atypical antipsychotic drugs in patients with Alzheimer’s disease.- Predictors of progression from mild cognitive impairment to Alzheimer disease.- Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis.- Personality and risk of Alzheimer’s disease: New data and meta-analysis.- Modifiable predictors of dementia in mild cognitive impairment: a systematic review and meta-analysis.- Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis.- Meta-analysis of modifiable risk factors for Alzheimer’s disease.- Memantine for Alzheimer's Disease: An Updated Systematic Review and Meta-analysis.- Update on the Risk of Motor Vehicle Collision or Driving Impairment with Dementia: A Collaborative International Systematic Review and Meta-Analysis.- Pharmacological interventions for apathy in Alzheimer's disease.- Section 11: Sleep Disorders.- Behavioral and Pharmacological Therapies for Late-Life Insomnia: A Randomized Controlled Trial.- Cognitive behavioral therapy vs zopiclone for treatment of chronic primary insomnia in older adults: a randomized controlled trial.- Suvorexant in Elderly Patients with Insomnia: Pooled Analyses of Data from Phase III Randomized Controlled Clinical Trials.- Cognitive behavior therapy for older adults with insomnia and depression: a randomized controlled trial in community mental health services.- Section 12: Suicides.- Medical Illness and the Risk of Suicide in the Elderly.- The Risk of Suicide with Selective Serotonin Reuptake Inhibitors in the Elderly.- Section 13: Substance Use Disorders.- Naltrexone as an Adjunctive Treatment for Older Patients with Alcohol Dependence.- Older adult patients with both Psychiatric and Substance abuse disorders: Prevalence and Health service use.- Five-year alcohol and drug treatment outcomes of older adults versus middle-aged and younger adults in a managed care program.- Treatment of Late-Life Depression Complicated by Alcohol Dependence.- Screening and Brief Intervention for Substance Misuse Among Older Adults: The Florida BRITE Project.

Read more less

Book SynopsisThis volume discusses hazardous environmental micropollutants, their impacts on human health, and possible means to mitigate their associated risks. The book features chapters that cover a variety of topics related to environmental micropollutants, which include dusts, infectious particles, heavy metals, organophosphates, atmospheric toxic organic micropollutants, fungal spores, pollutants from E-waste, antibiotic waste, and more. In addition impacts on human health and the environment, economic issues are addressed, with potential policy solutions offered. This work is timely, as hazardous micropollutants in soil, water and air are becoming more common, and this environmental contamination is leading to increasing instances of suboptimal human health outcomes. The book will be of interest to students and researchers in environmental pollution and remediation technology, microbiologists, and environmental regulators. Table of ContentsChapter 1-Environmental Micropollutants.- Chapter 2-Infectious Diseases, Challenges and their Impacts on Human Health under Changing Climate.- Chapter 3-Marble Dust as an Environmental and Occupational Hazard.- Chapter 4-Impacts of Micropollutants on Economy and Main Spheres of Environment: Soil, Air and Water.- Chapter 5-Micropollutants Impacts and Preventive Measures to Reduce Diseases Burden among School Children.- Chapter 6-Emerging Organic Contaminants, Pharmaceuticals and Personal Care Products (PPCPs): A Threat to Water Quality.- Chapter 7-Environmental and Health Effects of Heavy Metals and their Treatment Methods.- Chapter 8-Organophosphates Pollution Status and their Remediation through Microbial Interaction in 21st Century.- Chapter 9-Atmospheric Toxic Organic Micropollutants.- Chapter 10-Impact of Aerial Fungal Spores on Human Health.- Chapter 11-Health Risks Associated with Arsenic Contamination and its Biotransformation Mechanisms in Environment: A Review.- Chapter 12-E-waste Threaten to Environment and Public Health.- Chapter 13-Manufacturing and use of flame retardant chemicals and their impact on the environment and public health.- Chapter 14-Mycotoxins in Environment and Its Health Implications.- Chapter 15-Antibiotics; Multipronged Threat to Our Environment.- Chapter 16-Microplastic pollution and Their Health Impacts.- Chapter 17-Treatment Technologies for the Environmental Micropollutant.

Read more less

Book SynopsisThis book is the first comprehensive text dedicated to risk assessment in the primary prevention of atherosclerotic cardiovascular disease. It provides an overview of current evidence regarding approaches to risk assessment, traditional and emerging risk factors, and atherosclerosis imaging for refinement of risk estimation. The volume seeks to provide an essential resource for professionals in the field to assess their patients for risk of cardiovascular disease. The book is divided into five sections, starting off with an overview of current best practices to risk assessment in primary prevention around the world. The second section discusses traditional risk factors, such as hypercholesterolemia, hypertension, diabetes, smoking, and obesity. The third section reviews the newly introduced concept of ‘Risk Enhancers’. The fourth section offers insight on novel risk factors, with in-depth discussion regarding lipoprotein(a), high-sensitivity CRP, apolipoprotein B, social determinants of health, stress and cardiovascular disease. and polygenic risk scores. The final section covers the use of non-invasive atherosclerosis imaging (computed tomography and ultrasound-based techniques) as a tool to refine risk estimates. Throughout the book, readers will find multiple tables, figures, and illustrations that complement the text. Up-to-date, evidence-based, and clinically oriented, Cardiovascular Risk Assessment in Primary Prevention is a must-have resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.Table of ContentsSection 1General Principles and Approach to Risk Assessment in Primary Prevention – Anne Marie Navar (Duke University)U.S. Guidelines – Roger Blumenthal (Johns Hopkins University)European Guidelines – Salim Virani (Baylor College of Medicine)Canadian Guidelines – Robert Hegele (Robarts Research Institute; Ontario, Canada)Asian Guidelines – Mariko Harada-Shiba (National Cerebral and Cardiovascular Center; Japan)Section 2 - Traditional Risk FactorsHypercholesterolemia – Christie Ballantyne (Baylor College of Medicine)Hypertension – Ron Blankstein (Brigham and Women’s Hospital)Diabetes – Mikhail Kosiborod (University of Missouri – Kansas City)Smoking – Pamela Morris (Medical University of South Carolina)Obesity - Jamie Ard (Wake Forest University School of Medicine)Section 3 - Risk EnhancersFamily history of premature atherosclerotic cardiovascular disease – Amit Khera (UT Southwestern)Conditions Specific to Women – Martha Gulati (University of Arizona – Phoenix)Ethnic Factors – Pam Taub (UC San Diego)Triglyceride Rich Lipoproteins – Sergio Fazio (Oregon Health & Science University)Inflammatory Diseases – Erin Michos (Johns Hopkins University)Chronic Kidney Disease – Barry Freedman (Wake Forest University School of Medicine)Metabolic Syndrome – Harold Bays (Louisville Metabolic and Atherosclerosis)Ankle Brachial Index – Peter Toth (CGH Medical Center)Section 4 – Novel Risk FactorsLipoprotein(a) – Mike Blaha (Johns Hopkins University)High-sensitivity C-Reactive Protein - Paul Ridker (Brigham and Women’s Hospital)Apolipoprotein B – Seth Martin (Johns Hopkins University)Social Determinants of Health – Keith Ferdinand (Tulane University)Clonal Hematopoiesis of Indeterminate Potential – Pradeep Natarajan (Massachusetts General Hospital)Polygenic Risk Scores – Amit Khera (Massachusetts General Hospital)Metabolomics – David Herrington (Wake Forest University School of Medicine)Section 5 – Atherosclerosis Imaging as a Tool to Refine Risk EstimatesCoronary Artery Calcium Score – Khurram Nasir (Houston Methodist Debakey Heart Center)Coronary Computed Tomography Angiography – Kavitha Chinnaiyan (Beaumont Health)Carotid Intima-Media Thickness – Jim Stein (University of Wisconsin)

Read more less

Book SynopsisThis book addresses the need for improved diagnostic and treatment guidelines for patients in whom total knee arthroplasty (TKA) has had an unsatisfactory outcome. It opens by discussing the basics of TKA and the various causes of failure and pain. Diagnostic aspects are considered in detail, with attention to advances in clinical investigation, laboratory analysis and in particular, imaging techniques. In addition, helpful state of the art diagnostic algorithms are presented. Specific pathology-related treatment options, including conservative approaches and salvage and revision TKA strategies, are then explained, with identification of pitfalls and key points. A series of illustrative cases cover clinical scenarios frequently encountered in daily clinical practice. The evidence-based, clinically focused guidance provided in this book, written by internationally renowned experts, will assist surgeons in achieving the most effective management of these challenging cases.Table of ContentsBasics of total knee replacement: Anatomy and biomechanics of the knee after total knee arthroplasty.- Biology of the knee after TKA- the neglected potential or source of failure?- There is an optimal axial alignment in TKA- rotation does matter!- There is an optimal alignment of the TKA- tibial rotation does matter!- Gap balancing in total knee arthroplasty- the US perspective.- Design, shape, and materials of total knee arthroplasty - What works well, what does not.- Patellofemoral complications and mal-tracing in TKA are influenced by what?- Image analysis- new ways to improve the diagnosis in patients after TKR.- How can preoperative planing prevent occurrence of a painful TKA? Causes of pain after TKA: Avoiding Wound Complications in Total Knee Arthroplasty- Failure of the TKA implant.- Periprosthetic fractures following total knee replacement- an epidemic problem on the rise!- Malposition and malorientation of TKA.- The problem of under- or oversizing of TKA.- Instability of TKA.- Extensor mechanism deficiency in TKA.- Causes and diagnosis of aseptic loosening after TKA.- Infection after TKA.- Allergy and hypersensitivity to implant materials in patients with TKA: an allergological approach.- Stiffness after total knee arthroplasty.- The unhappy TKA: Reducing the impact of psychological factors on outcome.- Impingement after TKA. Diagnostics: Medical History and physical examination.- Laboratory analysis in the assessment of painful total knee arthroplasty.- What do the radiographs tell us?- CT determination of component orientation and position in patients after TKA.- Magnetic resonance imaging in knee arthroplasty.- The diagnostic value of SPECT/CT in the ‘unhappy’ total knee arthroplasty- a potential for better diagnosis!- FDG-PET in patients with total knee arthroplasty - what is the evidence?- Fluoroscopy and stress radiographs diagnosing laxity/instability in patients after TKA.- Biopsy, joint puncture, diagnostic arthroscopy.- A diagnostic algorithm for patients with painful total knee arthroplasty – what to do when?- Algorithm for the management of patients with painful total knee arthroplasty Treatment principles - Conservative treatment: Management of patients with painful total knee arthroplasty: A multimodal approach.- Pain after TKA- when is a conservative treatment possible?- Radiosynovectomy.- Physical therapy, alternative treatment options, braces/orthotics.- Treatment principles -Surgical treatment: General Principles.- Exposure for revision TKA.- Intraoperative landmarks in revision surgery- when to choose what?- Arthroscopic treatment of patellofemoral soft tissue impingement after posterior stabilized total knee arthroplasty.- Arthroscopic or open treatment of stiff knees after TKA.- Treatment of aseptic loosening.- Treatment of Instability after TK.- Cementless versus cemented revision TKA.- Use of stems in revision TKA.- Ligament and gap balancing in revision TKA.- Unusual causes of failure and unexpected complications.- My algorithm treating infection after TKA.- My special case of infection after total knee arthroplasty.- Joint line restoration in revision surgery.- Treatment of patellofemoral pain after TKA.- Hinged implants for revision TKA.- The management of bone loss in revision TKA.- My experience with diagnosis and treatment of extensor apparatus insufficiencies.- Low-grade infection after total knee arthroplasty.- Treatment of infection after TKA- one stage versus two stage.- Navigated revision arthroplasty- what is the benefit?- Periprosthetic fracture treatment in TKA.- Salvage procedures in revision TKA.- Future developments and perspectives. Case discussion.

Read more less

Book SynopsisThe present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease. Trade Review“The editors, who are experienced pharmacologists … have provided a comprehensive coverage of pharmacotherapy of heart diseases backed by a review of the pathophysiologic basis of the disease and therapy. … would be of immense value for physicians treating heart disease and allied professionals in pharmaceutical and biomedical backgrounds who have an interest in cardiology. … this book will prove a valuable resource as recent advances are covered well by experts in the respective fields.” (Raja J. Selvaraj, Journal of Pharmacology and Pharmacotherapeutic, Vol. 7, 2016)“The book is an extensive ‘link’ between ‘How’ cardiovascular system works at molecular and signaling pathway levels … . Overall, it is a fantastic attempt to demystify cardiovascular diseases at cellular and molecular levels and utilize the knowledge to potentially change the way cardiology is practiced and learned. … it is a book worth a read for those involved in cardiovascular research … .” (Kamal H. Sharma, Indian Journal of Pharmacology, Vol. 47 (6), December, 2015)Table of ContentsHeart Failure.- Cardiac Hypertrophy.- Cardiac Arrhythmias.- Valvular Heart Disease.- Coronary Heart Disease.- Management of Pericarditis.- Hypertension.- Atherosclerosis and hyperlipidemia.- Cardiovascular Conditions of Childhood.- Sudden Cardiac Death.- Peripheral artery disease.

Read more less

Book SynopsisLifestyle – the manner in which people live – is fundamental to health, wellness, and prevention of disease. It follows that attention to lifestyle is critically important to effective and successful health care. But here’s the challenge: health care professionals receive very little, if any, formal training about lifestyle counseling and therefore are ill equipped to incorporate lifestyle issues into clinical practice. In response, “Lifestyle Medicine” is evolving as a means to fill this knowledge gap. Lifestyle medicine approaches health and wellness by harnessing the power of lifestyle-related behaviors and influencing the environment we live in. It is a formal approach that promises to enhance and strengthen a re-invigorated health care system that is still outpaced by the epidemic proportions and complexity of chronic diseases like obesity, diabetes, depression, hypertension, and cancer, among others. Lifestyle Medicine: A Manual for Clinical Practice presents this formal approach in a pragmatic context. This unique and practical manual provides clear and succinct guidance on nearly all aspects of lifestyle medicine. The approach is both explanatory and pragmatic, providing case studies and bulleted translation of academic information into clinical practice recommendations. There is an emphasis on scientific evidence wherever possible as well as opinions by the expert chapter authors who practice lifestyle medicine. There is a “how-to” rationality to the book, consistent with a premise that any and all health care professionals should, and perhaps must, incorporate lifestyle medicine. A valuable checklist is included at the close of the book that summarizes key points and provides a practical tool for routine patient encounters.Trade Review“In 32 chapters the authors review the influence of lifestyle on medical conditions, but more important is how changes in lifestyle may improve these diseases. An interesting approach which has led to formation of the American College of Lifestyle Medicine. For clinical practitioners.” (Pediatric Endocrinology Reviews (PER), Vol. 14 (2), December, 2016)“Each chapter is a standalone monograph with an introduction, very short vignettes of a case history, followed by the psychological aspects, physical impact, some evidence-based management thoughts, resources, and references. … This book takes a comprehensive approach, covering many of areas that the single-issue monographs on this topic do not. As such this is a valuable overview that has tremendous value to primary care or specialist clinicians, and for supporting medical professionals such as nutritionists, physical therapists, and pharmacists.” (Vincent F. Carr, Doody's Book Reviews, July, 2016)Table of ContentsChapter 1Why Lifestyle Medicine?Chapter 2The Importance of Healthy Living and Defining Lifestyle MedicineChapter 3Communication and Behavioral Change Tools: A Primer for Lifestyle Medicine CounselingChapter 4Paradigms of Lifestyle Medicine and WellnessChapter 5Composite Risk Scores Chapter 6Clinical Assessment of Lifestyle and Behavioral Factors During Weight Loss TreatmentChapter 7Anthropometrics and Body CompositionChapter 8Physical Activity Measures Chapter 9Metabolic Profiles - Based on the 2013 Prevention GuidelinesChapter 10 The Chronic Care Model and the Transformation of Primary CareChapter 11 Guidelines for Healthy Eating Chapter 12A Review of Commercial and Proprietary Weight Loss ProgramsChapter 13Physical Activity ProgramsChapter 14Behavior Modification and Cognitive TherapyChapter 15Treating Tobacco Use in Clinical PracticeChapter 16Alcohol Use and ManagementChapter 17Sleep ManagementChapter 18Integrative MedicineChapter 19Transcultural Applications to Lifestyle MedicineChapter 20Community Engagement and Networks: Leveraging Partnerships to Improve LifestyleChapter 21Lifestyle Therapy as Medicine for the Treatment of ObesityChapter 22Lifestyle Therapy for Diabetes MellitusChapter 23Lifestyle Therapy in the Management of Cardiometabolic Risk: Diabetes Prevention, Hypertension, and DyslipidemiaChapter 24CancerChapter 25LIFESTYLE MEDICINE FOR THE PREVENTION AND TREATMENT OF DEPRESSIONChapter 26 Promoting Healthy Lifestyle Behaviors in Patients with Persistent PainChapter 27Forestalling Age-Related Brain Disordersiv>Chapter 28Chronic Kidney DiseaseChapter 29Non-alcoholic fatty liver disease and steatohepatitisChapter 30Gastroenterology Disease and Lifestyle MedicineChapter 31Lifestyle Medicine and Chronic Pulmonary DiseaseChapter 32Lifestyle Medicine and HIV-infected patients

Read more less

Book SynopsisDer vorliegende Leitfaden soll nicht nur über Grundlagen und HIV-assoziierte Krankheitsbilder informieren, sondern auch die Probleme der einzelnen Fachdisziplinen darstellen. Weitere Kapitel befassen sich mit der symptomorientierten Diagnosestellung und den psychosozialen Aspekten der HIV-Infektion.Table of ContentsI.Grundlagen.- I. 1 Epidemiologie.- I. 1.1 Weltweit.- I. 1.2 HIV/AIDS in Deutschland - Eckdaten und Trends, Ende 2001.- I.2 Das Virus.- I. 2.1 Aufbau.- I. 2.2 Vermehrung.- I. 2.3 Zielzellen für HIV.- I. 2.4 Übertragung.- I. 2.5 HIV-Subtypen.- I. 3 Infektionsverlauf.- I. 3.1 Klinischer Verlauf (ohne medikamentöse Therapie).- I. 3.2 Laborverlauf (ohne medikamentöse Therapie).- I.4 Immunologie (Jörg-Andres Rump).- I. 4.1 HIV und das Immunsystem.- II. Diagnostik.- II. 1 CDC-Klassifikation (1993).- II. 1.1 Die Laborkategorien 1 bis 3.- II. 1.2 Die klinischen Kategorien A bis C.- II. 2 HIV-Tests (Benedikt Weißbrich).- II. 2.1 Testberatung (Erdwine Klinker).- II. 3 Vorgehen bei diagnostizierter HIV-Infektion.- II.4 Laboruntersuchungen.- II. 4.1 Anforderungen an die Laborleistungen.- II. 4.2 Erstuntersuchung.- II. 4.3 Verlaufskontrolle und Untersuchungsfrequenz.- II. 4.4 Viruslastbestimmung (Bettina Gröschel).- III. Therapie.- III. 1 Antiretrovirale Therapie (ART).- III. 1.1 Prognose in Abhängigkeit von der Viruslast.- III. 1.2 Indikation für den Beginn der antiretroviralen Therapie.- III. 1.3 Aktuelle antiretrovirale Therapien beim unvorbehandelten Patienten.- III. 1.4 Einnahmehinweise für Medikamente zur antiretroviralen Therapie (in alphabetischer Reihenfolge).- III. 1.5 Nuldeosidale Reverse Transkriptaseinhibitoren (NRTI).- III. 1.6 Nicht-Nuleosidale Reverse Transkriptaseinhibitoren (NNRTI).- III. 1.7 Proteaseinhibitoren (PI).- III. 1.8 Kombinationsmöglichkeiten und Dosierungen von Proteaseinhibitoren (PI).- III. 1.9 Therapeutisches Drug Monitoring (TDM) (Hartwig Klinker).- III. 1.10 Neue antiretrovirale Substanzen.- III. 1.11 Übersicht zur Impfstoffentwicklung gegen die HIV-Infektion (Matthias T. Dittmar und Hans-Georg Kräusslich).- III. 1.12 Molekularbiologische und sonstige Therapieansätze.- III. 1.13 Strukturierte Therapiepausen.- III. 1.14 Immunglobuline (Martin Hartmann).- III. 1.15 HIV in Gynäkologie und Geburtshilfe (Matthias Beichert).- III. 1.16 Nadelstichverletzungen - Merkblatt (Martin Hartmann).- III. 1.17 Spezifische Nebenwirkungen (Martin Hartmann).- III. 1.17.1 Hautreaktionen unter antiretroviraler Therapie.- III. 1.17.2 Das Lipodystrophie-Syndrom (Martin Hartmann).- III. 1.17.3 Nebenwirkungen von Nukleosidanaloga in der antiretroviralen Langzeit-Therapie - mitochondriale Toxizität (Ulrich A. Walker).- III. 1.17.4 Hypersensitivitätssyndrom unter Abacavir (Thomas Stark und Ravi Walli).- III. 1.18 Therapieversagen (Thomas Stark).- III. 2 Resistenzentwicklung (Wirkverlust antiretroviraler Medikamente) (Klaus Heintz, Myriam Mendila und Ravi Wall).- III. 2.1 ANRS Algorhythmus für NRTIs.- III. 2.2 ANRS Algorhythmus für NNRTIs.- III. 2.3 ANRS Algorhythmus für PIs.- III. 3 Komplementäre Therapieformen.- IV. Häufigste Krankheitsbilder und Ihre Therapien.- IV. 1 Orale Haarleukoplakie.- IV. 2 Candida-Infektionen.- IV. 2.1 Medikamente gegen Candida-Infektionen.- IV. 3 Herpes simplex-Infektionen.- IV. 3.1 Medikamente gegen Herpes simplex-Infektionen.- IV. 4 Varizella zoster-Infektionen.- IV. 4.1 Medikamente gegen Varizella zoster-Infektionen (Herpes zoster).- IV. 5 CMV-Infektionen.- IV. 5.1 Medikamente zur Therapie von CMV-Infektionen.- IV. 6 Pneumocystis carinii-Pneumonie (PcP).- IV. 6.1 Medikamente gegen Pneumocystis carinii-Pneumonie (PcP).- IV. 7 Zerebrale Toxoplasmose.- IV. 7.1 Medikamente gegen zerebrale Toxoplasmose.- IV. 8 Tuberkulose.- IV. 8.1 Medikamente gegen Tuberkulose.- IV. 9 Atypische Mykobakteriose.- IV. 9.1 Medikamente gegen atypische Mykobakteriose.- IV. 10 Kryptosporidiosen.- IV. 10.1 Medikamente gegen Kryptosporidiosen.- IV. 11 Aspergillose.- IV. 11.1 Medikamente gegen Aspergillose.- IV. 12 Kryptokokkose.- IV. 12.1 Medikamente gegen Kryptokokkose.- IV 13 Wasting-Syndrom.- IV. 14 HIV-Enzephalopathie.- IV. 15 Kaposi-Sarkom (KS).- IV. 16 Lymphome.- IV. 17 Andere Tumoren.- V. Neue Krankheitsbilder.- V. 1 Hepatitis-Koinfektion (Hepatitis B-Virus, Hepatitis C-Virus, GB Virus C/Hepatitis G-Virus) (Hartwig Klinker).- VI. Vom Symptom zur Diagnose (Hartwig Klinker).- VI. 1 Fieber und/oder Gewichtsverlust.- VI. 2 Gastrointestinaler Symptomenkomplex.- VI. 3 Pulmonaler Symptomenkomplex.- VI. 4 Neurologisch-psychiatrischer Symptomenkomplex.- VI. 5 Ophthalmologischer Symptomenkomplex.- VII. Sonstiges.- VII. 1 Dermatologische Manifestationen bei HIV-Infektion.- VII. 1.1 Viren.- VII. 1.2 Bakterien.- VII. 1.3 Pilze.- VII. 1.4 Sonstige.- VII. 2 Neurologische Manifestationen (Eva Schielke).- VII. 2.1 Zerebrale Erkrankungen.- VII. 2.1.1 HIV-Enzephalopathie.- VII. 2.1.2 Zerebrale Toxoplasmose.- VII. 2.1.3 Kryptokokken-Meningitis.- VII. 2.1.4 Primäres ZNS-Lymphom.- VII. 2.1.5 Progressive multifokale Leukenzephalopathie (PML).- VII. 2.2 Erkrankungen des Rückenmarks und des peripheren Nervensystems.- VII. 2.2.1 HIV-assoziierte Myelopathie.- VII. 2.2.2 HIV-assoziierte akute Polyradikulitis (Guillain-Barré-Syndrom).- VII. 2.2.3 CMV-Myeloradikulitis.- VII. 2.2.4 HIV-assoziierte distal-symmetrische Polyneuropathie.- VII. 2.3 Erkrankungen der quergestreiften Muskulatur.- VII. 2.3.1 HIV-assoziierte Myopathie.- VII. 3 Häufigste Augenaffektionen (Hermann Gümbel).- VII. 4 Diagnose und Therapie der HIV-Infektion bei Kindern.- VII. 4.1 Betreuung von HIV1-exponierten und HIV1-positiven Kindern (Bernd Buchholz und Thomas Böhler).- VII. 4.1.1 Einleitung.- VII. 4.1.2 Betreuung von HIV1-exponierten Neugeborenen.- VII. 4.1.3 Ausschluss oder Diagnose der HIV1-Infektion.- VII. 4.1.4 Behandlung von HIV 1-positiven Kindern.- VII. 5 HNO-Manifestationen (Wilfried Pfitzer).- VII. 5.1 Äußeres Ohr/Gehörgang.- VII. 5.2 Mittelohr.- VII. 5.3 Innenohr.- VII. 5.4 Nasen- und Nasennebenhöhlen.- VII. 5.5 Mundhöhle.- VII. 5.6 Pharynx/Larynx.- VII. 5.7 Speicheldrüsen.- VII. 6 Zahnkomplikationen (Gernot Eigel).- VII. 7 Impfschutz (Klaus Fleischer).- VII. 8 Antiretrovirale Therapie bei HIV-infizierten Drogenkonsumenten Planung, Auswahl der Substanzen, Abfolge der Therapieregimes, Monitoring (Jörg Gölz).- VII. 8.1 Basisdiagnostik.- VII. 8.2 Integration des sozialen, toxicomanen, psychiatrischen und somatischen Syndroms zu einer Therapieplanung.- VII. 8.3 Compliance.- VII. 8.4 Somatische Komorbidität und Komedikation.- VII. 8.5 Antiretrovirale Therapiestrategien bei Drogenabhängigen.- VII. 9 Tipps zur Lebensführung.- VII. 10 Psychiatrische Krankheitsbilder und Behandlungsstrategien (Regina v. Einsiedel).- VII. 11 Psychotherapie bei HIV-Patienten (Petra Losse-Brust).- VII. 12 Schmerztherapie.- VII. 13 Ernährung (Achim Schwenk und Gisela Kremer).- VII. 13.1 Mangelernährung.- VII. 13.2 Methoden der Ernährungstherapie.- VII. 13.3 Medikamentöse Therapie der Mangelernährung.- VII. 13.4 Ernährungsprobleme und Lösungen.- VII. 14 Die Rolle des Hausarztes.- VII. 15 Klinische Bilder.- Abb. 1: Pneumocystis carinii-Pneumonie.- Abb. 2: Lymphom.- Abb. 3: Toxoplasmoseherde im Gehirn.- Abb. 4: Progressive multifokale Leukenzephalopathie (PML).- Abb. 5: Atypische Mykobakteriose.- Abb. 6: CMV-Retinitis.- Abb. 7: Orale Haarleukoplakie.- Abb. 8: Exiccationsekzem.- Abb. 9: Herpes zoster.- Abb. 10: Orale Candidose.- Abb. 11: Verrucae.- Abb. 12: Mollusca contagiosa.- Abb. 13: Psoriasis.- Abb. 14: Kaposi-Sarkom.- Abb. 15: Kaposi-Sarkom.- VII. 16 Literaturliste.- VIII. Adressenverzeichnis.

Read more less

Book SynopsisThis well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease.Trade Review“Intraocular Inflammation is an encyclopedic treatise on uveitis. … The authors walk us through all the nuances of ocular inflammatory diseases, making this an excellent go-to book for doctors working in this subspecialty. It would also be useful for general ophthalmologists looking for ‘in-depth’ reading on a particular condition.” (Zaria Ali, Eye News, Vol. 25 (2), August-September, 2018)Table of ContentsFrom the Contents: Anatomy.- Classification and Terminology.- Immunology and Experimental Uveitis.- Epidemiology.- Evaluation (History, Examination).- Serology.- Fluorescence Angiography/Indocyanin Angiography.- Ocular Coherence Tomography.- Electrodiagnostic Tests.- Ultrasonography.- Ocular Biopsy.- Diagnostic Vitrectomy.- Laser Flare Photometry.- AC Diagnostics.- Diagnostic Imaging Procedures.- Genetics.- Uveitis and Clinical Trials.- Evidence Based Medicine.- General Considerations.– Corticosteroids.- Non-Steroidal Anti-Inflammatory Drugs.- Anti-TNF-alpha-Blocking Agents.– Azathioprine.– Chlorambucil.– Cyclophosphamide.- New Drugs.- Intraocular Drug Delivery.– Cataract.– Macular Edema.– Glaucoma.- Subretinal Fibrosis.– Vitrectomy.- Anterior Uveitis.- Intermediate Uveitis.- Posterior Uveitis.- White-Dot-Syndrom.– Panuveitis.- Retinal Vasculitis.– Retinitis.- Uveitis in Children.

Read more less

Book SynopsisHandy – concise – clearThe “always on-hand” pocket guide to the treatment of infectious diseases.- The most important antibiotics and antimycotics:Spectrum – dosage – side-effects- Numerous tables sorted by substances, pathogens, indications- Administration of antibiotics during pregnancy, renal and hepatic insufficiency, dialysis- Including statements on the cost of therapyNumerous tips and troubleshooting guides on topics such as:- Potential mistakes- Therapy failures- Perioperative antibiotic prophylaxisAdjusted to European standards:Up-to-date substances, authorizations, resistances and trade names.The first guide to antibiotic therapy for Europe!All in all, an approach that looks towards the future in which antimicrobial resistance will certainly represent an ever-growing obstacle for the medical class, and for which books like this will undoubtedly represent a precious resource.Giuseppe Cornaglia, MD, PhDPresident, European Society of Clinical Microbiology and Infectious Diseases (ESCMID)This book will most certainly be a valuable asset for all those treating patients with infections. While primarily aimed at the hospital setting, most of the very useful information can certainly be used in other healthcare settings, too.Andreas VossProfessor of Clinical Microbiology and Infection ControlRadboud University Nijmegen Medical Centre and Canisius-Wilhelmina HospitalNijmegen, The NetherlandsTable of Contents1 Classification of the Antibiotics.- 2 Generic and Trade Names – Trade Names and Generics.- 3 Principles of Antibiotic Therapy.- 4 The Most Common Errors in Antibiotic Therapy.- 5 Important Infections and Their Microbiological Diagnosis.- 6 Cooperation with Microbiologists.- 7 Resistance of Major Clinical Pathogens.- 8 The Most Frequent Pathogens – Choice of Antibiotics.- 9 Antibiotics, Antimycotics: Spectrum – Dosage – Adverse Effects – Costs.- 10 Antibiotic Therapy of the Principal Infections in Children and Adults.- 11 Treatment of the Most Frequent Types of Bacterial Endocarditis.- 12 Minimal Duration of Treatment for Bacterial Infections.- 13 Failure of Antibiotic Therapy.- 14 Fever of Unknown Origin: Differential Diagnosis.- 15 Dosage of Antibiotics in Impaired Renal Function.- 16 Antibiotic Therapy in Hemodialysis, Peritoneal Dialysis, and Continuous Hemofiltration.- 17 Antibiotic Therapy During Pregnancy and Lactation.- 18 Antibiotics in Liver Diseases.- 19 Diffusion of Antibiotics in Cerebrospinal Fluid and in Cerebral Abscesses.- 20 Local Antibiotics.- 21 Prophylactic Antibiotic Therapy.- 22 Physical Incompatibility of Antibiotics and Antimycotics in Infusion Solutions.- 23 Useful Websites.- Subject Index.

Read more less

Book SynopsisDas Referenzwerk zur pädiatrischen Pneumologie wurde von einem neuen Herausgeberteam grundlegend überarbeitet. Spezialisten aus Deutschland, Österreich und der Schweiz haben bei diesem umfassenden Praxisbuch mitgewirkt, das sich an dem European Training Syllabus der European Academy of Paediatrics orientiert. Lückenlos präsentiert das Buch das fundierte Spezialwissen zu Atemwegserkrankungen bei Kindern und Jugendlichen von den respiratorischen Erkrankungen des Früh- und Neugeborenen bis hin zu Asthma, obstruktiven Atemwegserkrankungen, Pneumonie und seltenen Lungenerkrankungen. Der Bogen wird gespannt von den verständlich dargestellten Grundlagen des gesunden Respirationstraktes über die diagnostischen Techniken bis hin zu den Erkrankungen des Respirationstraktes, die nach einer einheitlichen Struktur ausführlich und praxisnah beschrieben sind.Spezielle Therapien wie Inhalationstherapie oder Heimbeatmung bilden einen weiteren Schwerpunkt des Buches. Das wichtige Thema der Interaktionen mit anderen Fachgebieten wurde neu ins Buch aufgenommen, darunter intensivmedizinische Aspekte, Difficult Airway Management oder kinderchirurgische Aspekte. Damit ist dieses Referenzwerk für alle Ärzte nützlich, die mit pädiatrischer Pneumologie in Berührung kommen. Zum Lesen, Lernen und Nachschlagen.Trade ReviewAus den Rezensionen: “... Das Stichwortverzeichnis ist ungewöhnlich gut und ausführlich. ... Das Buch ist jedem klinisch Tätigen und verantwortungsbewussten Kinderarzt zu empfehlen, außerdem ist es das Nachschlagewerk für alle Kinderpneumologen und Spezialisten, die auf diesem wichtigen Arbeitsgebiet der Kinderheilkunde und Jugendmedizin arbeiten.“ (W.Kiess, in: Kinder- und Jugendmedizin, Heft 3, 2014)Table of ContentsI Der gesunde Respirationstrakt1 Strukturelle Entwicklung, Embriologie.- 2 Funktionelle Entwicklung der Lunge (Mechanik, Gasaustausch).- 3 Angewandte Physiologie.- 4 Physiologie des Schlafs und Atemregulation5 Abwehr.- 6 Umweltfaktoren.- 7 Genetik.- 8 EpidemiologieII Diagnostik9 Anamnese.- 10 Klinische Untersuchung.- 11 Lungenfunktionsdiagnostik.- 12 Bronchoskopie13 Bildgebung.- 14 Schlafuntersuchungen.- 15 Ziliendiagnostik.- 16 Gastro-ösophagealer Reflux17 Mikrobiologische Untersuchungstechniken.- 18 Allergologische Techniken.- 19 Immunologische Techniken .- 20 CFTR-Funktionstechniken.- 21 Genetische Diagnostik22 Techniken der Pleurapunktion, Drainagen, Thorakosopie, VATS, LungenbiopsieIII Erkrankungen des Respirationstraktes23 Respiratorische Erkrankungen des Früh- und Neugeborenen.- 24 Angeborene Lungenerkrankungen.- 25 Erkrankungen des pulmonalen Gefäßsystems.- 26 Infektionen.- 27 Obstruktive Atemwegserkrankungen.- 28 Cystische Fibrose.- 29 Bronchieektasen.- 30 PCD.- 31 Seltene Lungenerkrankungen.- 32 Lungentransplantation.- 33 Pädiatrisch-pneumologische Aspekte der Schlafmedizin.- 34 Psychogene und funktionelle Atemstörungen.- 35 Fremdkörperaspiration.- 36 Pleuraerguss, Pneumothorax, Chylothorax, HamatothoraxIV Spezielle Therapien37 Physiotherapie.- 38 Inhalationstherapie.- 39 Spez. Immuntherapie und Management der Anaphylaxie.- 40 Langzeitbetreuung bei chronischen Lungenerkrankungen.- 41 Schulungsprogramme42 Rehabilitation.- 43 Schmerztherapie.- 44 Palliativmedizinische AspekteV Interaktionen mit anderen Fachgebieten45 Intensivmedizinische Aspekte.- 46 Kinderchirurgische Aspekte der Pädiatrischen PneumlogieVI Abklärung klinischer Zeichen und Symptome47 Husten.- 48 Giemen. -49 Dyspnoe/ Tachypnoe.- 50 Verdacht auf zentrale Apnoen.- 51 Stridor52 Schnarchen.- 53 Heiserkeit.- 54 Thoraxschmerz.- 55 ZyanoseVII Anhang56 Weiterbildungskatalog (Dt,CH, Au, Europa).- 57 Online-Weiterbildung.- 58 Wichtige Homepages und Fachgesellschaften

Read more less

Book SynopsisKurz vor einer Prüfung gerät man schnell mal unter Zeitdruck. Und die besten Lernpläne schützen nicht vor dem Gefühl, sich doch nicht richtig vorbereitet zu haben.„Innere Medizin“ gehört hier zu den ganz großen Brocken! Eine Menge Stoff, haufenweise Fragen im Examen, Grundlagenwissen für viele andere Fachgebiete – wer da nicht ins straucheln kommt…Glückwunsch.Gut, wenn man aber auf ein Buch zurückgreifen kann, das dank einer durchdachten Gliederung und sinnvoll gewichtetem Inhalt optimal durch die Prüfungsvorbereitung führt.„Innere Medizin… in 5 Tagen“ punktet durch: Praktische Relevanz Hinweise auf typische IMPP Fragen Klare Gliederung Verständlichkeit KürzeDas Werk ist nicht nur als Repetitorium kurz vor einer Prüfung geeignet, sondern auch als vorlesungsbegleitendes Kurzlehrbuch.In der 3. Auflage wurden alle Kapitel sorgfältig überarbeitet und aktualisiert.Trade ReviewAus den Rezensionen:“... ist nicht nur gut zur Vorbereitung auf das zweite Staatsexamen geeignet,sondern stellt auch für den gesamten klinischen Abschnitt des Medizinstudiums eine hervorragende und wichtige Hilfe dar ... eignet sich das Buch sehr gut zum Lernen und ist empfehlenswert. ... Verständlichkeit und Hinweise auf typische IMPP-Fragen begleiten optimal durch die Prüfungsvorbereitung ...“ (Veronika Gebhardt, in: webcritics.de, 6. November 2014) “... Das Buch ist im Kurzlehrbuchstil gehalten und beinhaltet alle wichtigen Erkrankungen der Inneren Medizin, die in stichpunktartiger Form abgehandelt werden. Das Konzept des Buches beruht darauf, das komplette examensrelevante Wissen in 5 Tagen zu lernen. ... Die einzelnen Krankheitsbilder werden zunächst kurz beschrieben und weiterhin in Klinik, Diagnostik und Therapie unterteilt. ... ist die Sprache leicht verständlich und gut zu lesen und die Einteilung in verschiedene Lerntage macht die Organisation der Lernzeit einfacher und übersichtlicher ...“ (in: Fachschaft Medizin Münster, fsmed-muenster.de, 1.Dezember.2014)“... Die Stichpunkte sind immer sehr gut verständlich und an geeigneten Stellen eher satz- bzw. textartig gestaltet. ... Stadien und Klassifikationen werden zudem in Lerntabellen aufgeführt, aber auch im sonstigen Text erläutert ...“ (in: FiMM Fachschaftsinitiative Medizin Mannheim FiMM-online.de, September 2014)Table of ContentsTag 1: Kardiologie und Angiologie.- Tag2: Pneumologie und Infektiologie.- Tag 3: Gastroenterologie und Stoffwechsel.- Tag 4: Hämatologie und Rheumatologie.- Tag 5: Nephrologie und Endokrinologie.

Read more less