Clinical and internal medicine Books

1991 products


  • Get Inside Your Doctors Head

    Johns Hopkins University Press Get Inside Your Doctors Head

    1 in stock

    Book SynopsisFollow the Ten Rules to make decisions in the increasingly complicated medical world when you need guidance about health matters for yourself and your loved ones.Trade ReviewIt's a small book, but it's full of big and invaluable advice. Publishers Weekly A powerful discussion highly recommended as a basic primer to medical professional thought processes, and will appeal to any general-interest health collection. Midwest Book Review Well written and easy to pick up and understand. it is obviously written for the lay person but is definitely not patronising or demeaning, delivery an easy read for professionals and lay persons alike... nice pocket sized companion that if not carried... should remain on hand, on a desk or book shelf. -- Ibadete Fetahu Nursing TimesTable of ContentsIntroduction: Applying and Breaking the Rules1. If You Don't Know What You're Doing, Don't Do Anything2. If What You're Doing Seems to Be Working, Think about Continuing It3. If What You're Doing Doesn't Seem to Be Working, Think about Doing Something Else4. Don't Agree to an Invasive Procedure without Understanding Why It's Needed—and without Getting a Second Opinion5. If You Don't Have Symptoms, a Doctor Can't Make You Feel Better6. Never Trust Anyone Completely, Especially Purveyors of Conventional Wisdom7. Most Things Are What They Seem to Be, Except When They're Not8. What Your Doctor Doesn't Know Could Kill You9. Timing Is Everything, and Sometimes Time Is the Cure10. Caring Is Always Important MedicineEpilogue: The Participatory Art of MedicineRecap: The Rules RevisitedAcknowledgmentsAppendix: Additional Information about the Common Illnesses Discussed in This Book

    1 in stock

    £15.68

  • Obesity Interventions in Underserved Communities

    Johns Hopkins University Press Obesity Interventions in Underserved Communities

    4 in stock

    Book SynopsisThe obesity epidemic has a disproportionate impact on communities that are hard-hit by social and economic disadvantages. This book explores effective models for treating and preventing obesity in such communities.Trade ReviewThis book, therefore, serves as a showcase of recent grassroots movements that work across disciplines, health systems and sectors to address inequalities by using culturally appropriate approaches. Journal of Public HealthTable of ContentsForewordIntroduction. Advancing a New Conversation about Obesity in the UnderservedPart I: Literature ReviewsChapter 1. The Potential of Early Childhood Education as a Successful Obesity InterventionChapter 2. Latino Childhood ObesityChapter 3. Is That All There Is? A Comprehensive Review of Obesity Prevention and Treatment Interventions for African American GirlsChapter 4. Dietary Acculturation in U.S. Hispanic CommunitiesChapter 5. Obesity in Correctional Facilities: A Review of Epidemiology and EtiologyChapter 6. Weight Loss Interventions in the Mexican American CommunityPart II: CommentariesChapter 7. In the Way or On the Way? Asking Ourselves about the Role of Contextual Factors in Community- Based Obesity ResearchChapter 8. The Importance of Public Safety in Promoting Physical Activity and Curbing Obesity within African American CommunitiesChapter 9. Military and Civilian Approaches to the U.S. Obesity EpidemicChapter 10. A Healthy Weight Disparity Index and Reducing Rates of Obesity and Overweight in the United StatesPart III: Reports from the FieldChapter 11. Obesity Management Organized by Adolescents in Rural AppalachiaChapter 12. Winning Over Weight Wellness: A Culturally Relevant, Interactive Health Program for Underserved Faith- Based GroupsChapter 13. Latino Migrant Middle School Students as Videographers: Learning about Healthy ChoicesChapter 14. Creating Healthy Environments in Los Angeles through Joint Use of School FacilitiesChapter 15. The Idaho Partnership for Hispanic Health: Enabling Healthy Eating and Active Living in Rural IdahoChapter 16. Alliance for a Healthy Border: Obesity Prevention in Underserved U.S.- Mexico Border CommunitiesChapter 17. Comienzo Sano: Familia Saludable: Addressing Latino Childhood Obesity through a Community- Based Participatory Research and Bilingual Family- Focused CurriculumChapter 18. Fine, Fit, and Fabulous: Addressing Obesity in Underserved Communities through a Faith- Based Nutrition and Fitness ProgramChapter 19. Changes for Life: A Primary Care– Based Multidisciplinary Program for Obesity in Children and FamiliesChapter 20. The West Virginia PEIA Weight Management Program: An Innovative Approach to Obesity Prevention and Treatment in Appalachian CommunitiesChapter 21. SOPHE: Sustainable Solutions for Health EquityChapter 22. The Prevention of Obesity in Homeless Shelter SettingsChapter 23. Get FIT (Fitness Integration Training): A Program to Reduce Obesity and Metabolic Syndrome in People with Intellectual and Developmental Disabilities and Their CaregiversChapter 24. The PILI 'Ohana Project: A Community- Academic Partnership to Eliminate Obesity Disparities in Native Hawaiian and Pacific Islander CommunitiesChapter 25. Nutrition Education at Mobile Markets: Community- Engaged, Evidence- Based Interventions to Address Obesity in Low- Income Neighborhoods in MilwaukeeChapter 26. Report from a Pediatric Weight Management Program: Lessons Learned from Six Years of Experience with a Largely Medicaid- Based PopulationChapter 27. Healthy Children, Strong Families: Obesity Prevention for Preschool American Indian Children and Their FamiliesChapter 28. A Structured Weight Management Program for Obese Patients in an Urban Safety- Net Hospital CenterChapter 29. Creating Safe Neighborhoods for Obesity Prevention: Perceptions of Urban YouthChapter 30. Peer Influence on Obesity- Related Behaviors: Design and Rationale of the Waipahu HART ProjectChapter 31. Walking Groups: A Simple, Affordable Intervention Program for Public Housing DevelopmentsIndex

    4 in stock

    £35.10

  • Searching for Health

    Johns Hopkins University Press Searching for Health

    Book SynopsisAn insider's guide to searching online, communicating with your physician, and maximizing your health from a doctor who works at Google. We've all been there. Late at night, staring into the glow of a phone trying to make sense of some health-related issue that we know nothing about. In Searching for Health, Dr. Kapil Parakh, with Anna Dirksen, brings to life knowledge he gained from working at Google and practicing medicine. Helping readers avoid common pitfalls, get the information they need, and partner effectively with their health team to figure out a path to good health together, the book distills decades of scientific research into a set of easy-to-follow tips. It also incorporates firsthand accounts of common challenges on the path to good health; an inside look at how doctors approach and assess health-related information; techniques that consumers can use to locate evidence-based information online, whether in blogs, social media postings, forums, or news stories; guidanceTable of ContentsHow to Use This BookPrologueChapter 1. The First Signs of IllnessChapter 2. Moving from Symptoms to a DiagnosisChapter 3. Meeting with Your Doctor about Your DiagnosisChapter 4. Receiving a DiagnosisChapter 5. Deciding on TreatmentChapter 6. MedicationsChapter 7. SurgeryChapter 8. Lifestyle Treatment OptionsChapter 9. Complementary and Alternative TreatmentsChapter 10. Making Tough DecisionsAfterwordNotesIndex

    £15.68

  • Johns Hopkins University Press Weight Loss for Life

    20 in stock

    Book SynopsisThis is not a fad diet book. This is the most comprehensive, scientifically based program to lose weight and keep it off, with practical details about diet and nutrition, movement and motivation, medications, supplements, surgery, and more. In Weight Loss for Life, two experts from the Johns Hopkins Healthful Eating, Activity & Weight Program provide you with all of the information you need on your weight loss journey. They bring together leading experts in behavioral health, nutrition, exercise, and nursing to help you develop a plan that works best for youand that's not focused on just restricting calories or certain foods. Anyone struggling with unwanted weight gain or obesity will find this program to be helpful, compassionate, and clear. A central feature of the program is a Personal Plan of Action to help you set up reachable goals, plan your meals, and make time for movement. All the recommendations are customizable based on your personal health and needs. You'll enjoy the intTable of ContentsForewordAcknowledgmentsThe Johns Hopkins Healthful Eating, Activity & Weight ProgramChapter 1. We're Glad You're HereChapter 2. Getting ReadyChapter 3. Beginning Your Self-AssessmentChapter 4. Unlocking the Eight Keys to Your SuccessChapter 5. Strategic Stress ManagementChapter 6. Designing Your Dietary PlanChapter 7. Food Shopping, Meal Planning, and Monitoring PrinciplesChapter 8. Designing Your Daily Movement and Weekly Exercise PlanChapter 9. Keeping It OffChapter 10: Medical Solutions: Beyond Mindset and Behavior ChangeResourcesPersonal Plan of Action TemplateFood and Activity LogMovement and Activity AssessmentThe Energy Balance Equation AssessmentSMART FrameworkWeight Loss JournalReferencesIndex

    20 in stock

    £23.75

  • The Concise Guide to Bipolar Disorder

    Johns Hopkins University Press The Concise Guide to Bipolar Disorder

    15 in stock

    Book SynopsisTable of ContentsPrefacePart I. What Is Bipolar Disorder?Chapter 1. Normal and Abnormal MoodChapter 2. Types of Bipolar DisorderPart II. How Is Bipolar Disorder Treated?Chapter 3. Mood-Stabilizing MedicationsChapter 4. Atypical Antipsychotic and Antidepressant MedicationsChapter 5. More Medications, Hormones, and Nutritional SupplementsChapter 6. Brain Stimulation TreatmentsChapter 7. Essential Ingredients: Therapy and CounselingPart III. Getting Better and Staying Well: What You Can DoChapter 8. Living with Bipolar DisorderChapter 9. The Elements of Mood HygieneChapter 10. Preparing for EmergenciesChapter 11. Family MattersPart IV. What Causes Bipolar Disorder?Chapter 12. Bipolar Disorder in the BrainChapter 13. How Treatments WorkPart V. Putting It All TogetherChapter 14. Summing Up and Looking AheadSuggested ReadingReferencesIndex

    15 in stock

    £14.25

  • The Foot Book

    Johns Hopkins University Press The Foot Book

    1 in stock

    Book SynopsisNow completely revised and updated! The ultimate guide to taking care of your feet. Written by leading experts with decades of experience in podiatry, this new edition of The Foot Book covers everything you need to know to care for your feet. It addresses the entire foot, inside and out, describing in plain English its anatomy and biomechanical operations. The second edition also: Provides an overview of common and rare foot injuries and syndromes Includes information on alignment and balance problems, heel pain, skin and toe conditions, flat feet, arthritis, and more Offers guidance on medications, exercises, stretches, inserts, therapy, and surgery Explains how to select the right footwear and provides shoe recommendations Covers foot issues in children, athletes, people with diabetes, and people with nerve or vascular problems Includes links to supplemental videos that guide you through stretching, flexibility, and strengthening exercisesIllustrated with nearly 100 images, The FoTable of ContentsPrefacePart I. IntroductionChapter 1. A Guide to the Foot and How We WalkChapter 2. Personal Care and Professional Help for FeetChapter 3. About ShoesPart II. Foot Disorders and Other ProblemsChapter 4. Foot Alignment ProblemsChapter 5. Flat Feet and High-Arched FeetChapter 6. Skin Conditions Affecting the FootChapter 7. Toenail DisordersChapter 8. Bunions and Other Toe Conditions Chapter 9. Heel PainChapter 10. Nerve Syndromes Affecting the Foot and AnkleChapter 11. Arthritis Affecting Foot and Ankle JointsChapter 12. Tendon InjuriesPart III. People with Special Foot NeedsChapter 13. Foot Problems That Start in ChildhoodChapter 14. Common Sports Injuries and the Sports Enthusiast's FootChapter 15. Foot Health for People with DiabetesChapter 16. Orthotic Devices to Alleviate Foot ProblemsChapter 17. Puncture Wounds and Foreign BodiesResourcesIndex

    1 in stock

    £40.95

  • John Wiley and Sons Ltd Haimovicis Vascular Surgery

    3 in stock

    Book SynopsisTo improve the diagnosis and management of patients with vascular disease turn to the most authoritative and trusted reference for 36 years and counting . . . The role of the vascular surgeon has evolved. Vascular surgeons now perform minimally invasive vascular procedures and provide comprehensive care in addition to open surgery. Haimovici's Vascular Surgery, now in its 6th edition, has been extensively updated to provide you with: Expert perspectives on how the vascular surgery field has evolved so you continue to stay on the leading edge of this dynamic field Concise and practical advice about what these changes and new areas of practice mean to you the practitioner and trainee in the fields of vascular surgery, interventional cardiology and interventional radiology Fundamental principles and best practices to treat traditional and new modalities that are now part of the vascular surgeTrade Review“It is an excellent reference for vascular surgeons or trainees, and stands up well to other established vascular books. This is an important update with new chapters as well as revisions to relevant chapters with a specific focus on endovascular therapies and venous disease.” (Doddy’s, 7 December 2012) Table of ContentsPreface, x Preface to the Fifth Edition, xi Contributors, xii List of Abbreviations, xx PART I VASCULAR IMAGING TECHNIQUES AND PHYSIOLOGIC TESTING 1 Arterial and Venous Duplex Scanning, 3 Gregory L. Moneta 2 Duplex Arteriography for Lower Extremity Revascularization, 28 Enrico Ascher, Anil Hingorani, and Natalie Marks 3 Fundamentals of Angiography, 44 Douglas B. Hood and Kim J. Hodgson 4 Arteriographic Patterns of Atherosclerotic Occlusive Disease of the Lower Extremity, 56 Henry Haimovici 5 Computed Tomography in Vascular Disease, 79 Aoife N. Keeling, Peter A. Naughton, Frederick L. Hoff, and William H. Pearce 6 Magnetic Resonance Angiography, 99 April Farley, Javier E. Anaya-Ayala, Mark G. Davies, and Alan B. Lumsden 7 Intravascular Ultrasound Imaging, 112 George Kopchok and Rodney A. White PART II BASIC SCIENCE IN VASCULAR DISEASES 8 Hemodynamics of Vascular Disease: Applications to Diagnosis and Treatment, 127 David S. Sumner 9 Atherosclerosis: Biological and Surgical Considerations, 148 Bauer E. Sumpio 10 Neointimal Hyperplasia: Basic Considerations, 178 Lynn S. Model and Alan Dardik 11 Therapeutic Angiogenesis, 197 Bo Liu and K. Craig Kent 12 Thrombogenesis and Thrombolysis, 209 Takki A. Momin, Robyn A. Macsata, and Anton N. Sidawy 13 Etiology of Abdominal Aortic Aneurysms, 221 Sartaj S. Sanghera, Anil Hingorani, and Martin D. Tilson 14 An Evidence-based Approach to Cardiopulmonary Risk Assessment for Vascular Surgery Procedures, 233 Joel H. Horovitz PART III BASIC OPEN VASCULAR TECHNIQUES 15 Vascular Sutures and Anastomoses, 243 Henry Haimovici 16 Patch-graft Angioplasty, 253 Henry Haimovici 17 Endarterectomy, 259 Henry Haimovici 18 Balloon Angioplasty of Peripheral Arteries and Veins, 268 Douglas B. Hood and Kim J. Hodgson 19 Stents for Peripheral Arteries and Veins, 280 Samuel S. Ahn, Carber C. Huang, and Foster A. Hays 20 Thrombolytic Therapy for Peripheral Arterial and Venous Thrombosis, 301 Michael B. Silva Jr, Charlie C. Cheng, and Lorraine Choi PART IV OPEN SURGICAL EXPOSURE OF ARTERIES 21 Exposure of the Carotid Artery, 317 Henry Haimovici 22 The Vertebrobasilar System: Anatomy and Surgical Exposure, 320 Enrique Criado and Ramon Berguer 23 Trans-sternal Exposure of the Great Vessels of the Aortic Arch, 324 Calvin B. Ernst 24 Extrathoracic Surgical Exposure for Distal Revascularization of Brachiocephalic Branches, 331 Henry Haimovici 25 Open Surgical Exposure of Upper Extremity Arteries, 338 Henry Haimovici 26 Transperitoneal Exposure of Abdominal Aorta and Iliac Arteries, 351 Henry Haimovici 27 Retroperitoneal Exposure of Abdominal Aorta, 360 Calvin B. Ernst 28 Retroperitoneal Exposure of Iliac Arteries, 366 Henry Haimovici 29 Open Surgical Exposures of Arteries in the Lower Extremity, 372 Henry Haimovici PART V CEREBROVASCULAR INSUFFICIENCY 30 Medical Management of Carotid Artery Disease, 391 Russell H. Samson 31 Carotid Endarterectomy: Indications, Techniques, and Results, 405 Bruce A. Perler 32 Eversion Carotid Endarterectomy, 419 Jorge Rey, Sean P. Roddy, and R. Clement Darling III 33 Carotid Stenting: Indications, Techniques, and Results, 427 Tejas R. Shah and Peter L. Faries 34 Cerebral Protection Devices During Carotid Stenting, 437 Amit R. Shah and Evan C. Lipsitz 35 Vertebrobasilar Disease: Surgical Management, 448 Enrique Criado and Ramon Berguer 36 Nonatherosclerotic Cerebrovascular Disease, 456 Gary R. Seabrook PART VI AORTIC AND ILIAC ANEURYSMS 37 Indications, Techniques and Results of Open Repair of Ascending and Transverse Aortic Arch Aneurysms, 475 Hazim J. Safi , Anthony L. Estrera, Roy Sheinbaum, and Charles C. Miller III 38 Hybrid Repair of Aortic Arch Aneurysms, 486 Gustavo S. Oderich and Adam H. Power 39 Endovascular Management of Thoracic Aortic Aneurysms and Dissections, 504 Donald T. Baril and Michel S. Makaroun 40 Open Repair of Thoracoabdominal Aortic Aneurysms, 517 Joseph Huh, Scott A. LeMaire, and Joseph S. Coselli 41 Open Repair of Abdominal Aortic Aneurysms, 533 Colin M. Brady and Elliot L. Chaikof 42 Endovascular Repair of Infrarenal Abdominal Aortic Aneurysms, 554 Jeffrey Hnath, Manish Mehta, Yaron Sternbach, John B. Taggert, and R. Clement Darling III 43 Fenestrated and Branched Stent Grafts for the Treatment of Complex Aortic Aneurysms, 565 Joseph J. Ricotta II 44 Endovascular Treatment of Ruptured Infrarenal Aortic and Iliac Aneurysms, 582 Frank J. Veith and Neal S. Cayne 45 Open Surgical Treatment of Isolated Iliac Aneurysms, 590 Henry Haimovici 46 Endovascular Grafts in the Treatment of Isolated Iliac Aneurysms, 594 Todd L. Berland, Frank J. Veith, Karan Garg, and Neal S. Cayne 47 Infected Aortic Grafts: General Considerations and Techniques, 602 Taylor A. Smith and G. Patrick Clagett 48 Para-anastomotic Aortic Aneurysms: General Considerations and Techniques, 612 John J. Ricotta PART VII VISCERAL VESSELS 49 Surgery of the Celiac Artery for Occlusive Disease and Arcuate Ligament Syndrome, 627 Juan Carlos Jimenez and William J. Quinones-Baldrich 50 Management of Acute and Chronic Mesenteric Ischemia, 639 Natalia O. Glebova and Julie A. Freischlag 51 Endovascular Treatment of Mesenteric Occlusive Disease, 653 Carlos F. Bechara and Peter H. Lin 52 Renal Artery Revascularization, 664 Keith D. Calligaro and Matthew J. Dougherty 53 Renal Artery Fibrodysplasia and Renovascular Hypertension, 680 James C. Stanley and Jonathan L. Eliason 54 Visceral Artery Aneurysms, 690 Matthew J. Dougherty and Keith D. Calligaro PART VIII LOWER EXTREMITY OCCLUSIVE AND NON-OCCLUSIVE ARTERIAL DISEASE 55 Acute Arterial Occlusion of the Lower Extremities, 703 Kenneth Ouriel 56 Aortoiliac Occlusive Disease, 710 David C. Brewster 57 Endovascular Treatment of Aortoiliac Artery Stenosis and Occlusions, 736 Jeanwan Kang and Christopher J. Kwolek 58 Infrainguinal Arterial Disease, 749 John Byrne, R. Clement Darling III, and Frank J. Veith 59 Bypasses to Plantar Arteries and Other Branches of Tibial Arteries, 761 Enrico Ascher and Frank J. Veith 60 Role of Surgical Options for Critical Lower Limb Ischemia, 767 Frank J. Veith, Neal S. Cayne, Nicholas J. Gargiulo III, Evan C. Lipsitz, and Enrico Ascher 61 Adjuvant Surgical Techniques for Limb Salvage, 776 Robyn A. Macsata and Anton N. Sidawy 62 Endovascular Treatment of Infrapopliteal Arteries, 786 Peter A. Schneider, W. Austin Blevins, and Nicolas Nelken 63 Popliteal Artery Aneurysms, 801 Javairiah Fatima and Peter Gloviczki 64 Endovascular Treatment of Popliteal Artery Aneurysms: The Role of Stent-Grafts and Thrombolysis, 811 Alik Farber and Tze-Woei Tan 65 Duplex-guided Balloon Angioplasty for Infrainguinal Arterial Occlusive and Aneurysmal Disease, 821 Enrico Ascher, Natalie Marks, and Anil Hingorani 66 Extra-anatomic Bypasses, 832 Enrico Ascher, Frank J. Veith, and Kapil Gopal 67 Infected Extracavitary Prosthetic Grafts, 845 Keith D. Calligaro and Matthew J. Dougherty 68 Popliteal Entrapment and Chronic Compartment Syndrome: Unusual Causes for Claudication in Young Adults, 852 William D. Turnipseed 69 Lumbar Sympathectomy: Current Indications and Techniques, 860 Ali F. AbuRahma 70 Nonatherosclerotic Diseases of Small Arteries, 873 Henry Haimovici and Yoshio Mishima 71 Intraoperative Assessment and Postoperative Surveillance of Vascular Reconstructions, 898 Gustavo De Jesús-Gómez and Dennis F. Bandyk PART IX VASCULAR TRAUMA 72 Vascular Trauma, 909 Ramyar Gilani, Asher Hirshberg, and Kenneth L. Mattox 73 Ankle and Foot Fasciotomy for Compartment Syndrome of the Foot, 928 Enrico Ascher 74 Post-Traumatic Pain Syndrome: Complex Regional Pain Syndrome, 932 Ali F. AbuRahma and Albeir Y. Mousa PART X UPPER EXTREMITY VASCULAR DISEASE 75 Vasospastic Disease of the Upper Extremity: Primary Raynaud’s Syndrome, 949 Gregory L. Moneta and Gregory J. Landry 76 Arterial Surgery of the Upper Extremity, 962 Rodeen Rahbar, Richard F. Neville, and Anton N. Sidawy 77 Neurogenic Thoracic Outlet Syndrome and Pectoralis Minor Syndrome, 981 Richard J. Sanders 78 Venous Thoracic Outlet Syndrome, 997 Peter F. Lawrence, Hugh Gelabert, Brian G. DeRubertis, and David A. Rigberg 79 Arterial Thoracic Outlet Syndrome, 1004 Frank J. Veith and Juan Carlos Jimenez 80 Upper Thoracic Sympathectomy: Conventional Technique, 1015 Henry Haimovici 81 Thoracoscopic Sympathectomy, 1023 Igor Brichkov and Jason P. Shaw PART XI ARTERIAL-VENOUS MALFORMATION, ACCESS FOR HEMODIALYSIS AND PORTAL HYPERTENSION 82 Arteriovenous Fistulas and Vascular Malformations, 1035 Peter Gloviczki, Audra A. Noel, and Larry H. Hollier 83 Vascular Access for Dialysis, 1060 Andres Schanzer and Harry Schanzer 84 Portal Hypertension, 1078 Ian C. Carmody and John C. Bowen 85 Endovascular Treatment of Portal Hypertension, 1095 Yosef Golowa and Jacob Cynamon PART XII VENOUS AND LYMPHATIC DISORDERS 86 Clinical Application of Objective Testing in Venous Insufficiency, 1109 John J. Bergan and Warner P. Bundens 87 Varicose Veins, 1121 Jose I. Almeida and Jeffrey K. Raines 88 Superficial Thrombophlebitis, 1131 Anil Hingorani and Enrico Ascher 89 Acute Deep Vein Thrombosis and Contemporary Venous Thrombectomy, 1136 Anthony J. Comerota 90 Acute Upper Extremity Deep Venous Thrombosis, 1154 Anil Hingorani and Enrico Ascher 91 Vena Cava Filters, 1160 Linda M. Harris and Raphael Blochle 92 Repair of Iliac and Iliocaval Venous Obstructions, 1173 Seshadri Raju and Peter Neglen 93 Ablation of Major Incompetent Superficial Veins, 1185 Manju Kalra and Peter Gloviczki 94 Management of Perforator-vein Incompetence, 1201 Javier E. Anaya-Ayala, Mark G. Davies, Eric K. Peden, and Alan B. Lumsden 95 Ischemic Venous Thrombosis: Phlegmasia Cerulea Dolens and Venous Gangrene, 1213 Jesse M. Manunga Jr and Peter Gloviczki 96 Diagnosis and Management of Lymphedema, 1221 Harry Ma and Mark Iafrati PART XIII AMPUTATIONS AND REHABILITATION 97 Amputation of the Lower Extremity: General Considerations, 1239 Henry Haimovici 98 Major Amputations, 1243 Alexander Shiferson and Henry Haimovici 99 Postoperative and Preprosthetic Management for Lower Extremity Amputations, 1260 Yeongchi Wu 100 Prosthetic Fitting and Management of Lower Extremity Amputees, 1268 Jan J. Stokosa Index, 1287

    3 in stock

    £263.65

  • Successfully Choosing Your EMR

    John Wiley and Sons Ltd Successfully Choosing Your EMR

    10 in stock

    Book SynopsisThe Electronic Medical Record (EMR) - is the essential underpinning of any significant healthcare reform and is the more comprehensive record than the Electronic Health Record (EHR). This book clarifies the Crucial Decisions that result in successful EMR adoption and avoidance of expensive EMR mistakes. It provides timely insight in leveraging ARRA/HiTech, Meaningful Use, Stark Safe Harbor, CPOE and PQRI incentives and understanding current HITSP, HL7, ASTM, ELINCS and other interoperability standards. This book provides practical guidance on: Evaluating EMR ease-of-use Determining In-office vs. Web-based vs. Blended EMR deployment Deciding which user-interface approach to adopt Understanding structured vs. unstructured charting approaches Assessing EMR developer stability Obtaining legal advice about RFIs, RFPs and contract negotiations The federal government has set aside significant incentives for Trade ReviewThis is a timely text for any and all office practice managers who are considering obtaining an EHR or upgrading their current system. Then, too, our physician owners of their practice may choose to peek at this text as well. (Tennessee Medicine, May 2010)Table of Contents1. Why Adopt Electronic Medical Records Now? 2. How EMR Will Enhance Your Practice. 3. How EMR Will Impact Your CPM System. 4. Structured Data and Report Generation. 5. Interacting With Your EMR. 6. Where to Deploy Your EMR. 7. Vocabularies, Standards & Interoperability. 8. Interoperability Beyond EMRs. 9. Workflow Enhancement/EMR Customization. 10. Documenting Your Office Workflow. 11. Essential Medical Record Content. 12. Evaluating Vendor Stability. 13. Lawyer Proofing Your EMR. 14. Configuration & Deployment. 15. Crisis Planning and Mitigation. 16. Protecting Your Patient Data. 17. What You Can Expect to Spend. 18. Negotiating the Agreement. Appendix I. EMR Developers & Their Products. Appendix II. List of Conferences to View EMRs/EHRs. Appendix II. How the MSP EHR Selector™ Empowers Your EMR Search.

    10 in stock

    £54.95

  • ABC of Epilepsy

    John Wiley & Sons Inc ABC of Epilepsy

    3 in stock

    Book SynopsisABC of Epilepsy provides a practical guide for general practitioners, and all those working in primary care, on the diagnosis, treatment and management of epilepsy, and for the continued monitoring and long term support of what is still a relatively poorly understood neurological disorder.Trade Review“This monograph has great utility for clinicians and patients, and would be a valuable resource for a primary care setting library.” (Doody’s, 7 September 2012) Table of ContentsContributors, vii Foreword, ix Preface, xi 1 What is Epilepsy? Incidence, Prevalence and Aetiology, 1 W. Henry Smithson and Matthew C. Walker 2 Describing and Classifying the Condition, 4 Colin D. Ferrie and Matthew C. Walker 3 Making the Diagnosis – Taking a History, Clinical Examination, Investigations, 9 Jan Bagshaw, Matthew C. Walker, Colin D. Ferrie, Mike P. Kerr and W. Henry Smithson 4 Managing the Drug Treatment of Epilepsy, 14 Colin D. Ferrie, Mike P. Kerr, W. Henry Smithson and Matthew C. Walker 5 Non-drug Treatments Including Epilepsy Surgery, 18 Colin D. Ferrie, W. Henry Smithson and Matthew C. Walker 6 Prolonged or Repeated Seizures, 21 Matthew C. Walker 7 Special Groups – Women, Children, Learning Disability and the Elderly, 23 Jan Bagshaw, Colin D. Ferrie and Mike P. Kerr 8 Monitoring and Review – How to Manage the Condition Long Term, 27 Colin D. Ferrie, Alice Hanscomb and Mike P. Kerr 9 Living with Epilepsy – Information, Support and Self-Management, 30 Alice Hanscomb and W. Henry Smithson Appendix: Epilepsy Charities, 34 Index, 35

    3 in stock

    £27.50

  • Cancer Screening in the Developing World

    Dartmouth College Press Cancer Screening in the Developing World

    1 in stock

    Book SynopsisCase studies featuring real-world issues, problems, and solutions for cancer-screening programs in the developing world

    1 in stock

    £72.20

  • Cancer Screening in the Developing World

    Dartmouth College Press Cancer Screening in the Developing World

    1 in stock

    Book SynopsisCase studies featuring real-world issues, problems, and solutions for cancer-screening programs in the developing world

    1 in stock

    £31.35

  • Stem Cell Biology: Development and Plasticity,

    John Wiley and Sons Ltd Stem Cell Biology: Development and Plasticity,

    Book SynopsisStem cells have generated considerable interest recently in the scientific, clinical, and public arenas. It is essential that we gain a broader understanding of the factors that regulate the biology of stem cells: their ability for self-renewal, differentiation, and plasticity, as well as the differences between embryonic and adult stem cells. And to learn whether stem cells can be manipulated to replace cells in diseased tissues depends on better understanding their normal developmental properties. This volume offers contributions from numerous interdisciplinary areas bridging biotechnology and biomedical sciences. The ability to isolate and maintain pluripotent stem cells in culture offers exciting possibilities for replacing damaged or diseased organs and tissues. Moreover, stem cells will provide opportunities for major advances in our understanding of fundamental developmental processes. The study of pluripotent stem cells derived from early embryos or fetal tissues has shown that they are capable of replicating indefinitely in vitro and possess the ability to differentiate into many cell types. Biotechnological advances under which growth conditions and factors can be identified and characterized are needed to guide such cells to form organ-specific tissues. Biomedical researchers are also investigating approaches to isolate and manipulate adult-derived multipotential stem cells that appear to possess considerably broader differentiation capacity than originally imagined. Novel therapeutic strategies are being developed to take advantage of the ability of stem cells to proliferate in culture and to survive after transplantation into various tissues, where they may integrate and stably express foreign genes, or repopulate damaged or diseased organs such as the heart, brain, or pancreas. These presentations foster a broader understanding of the factors that regulate the biology and plasticity of stem cells through the picture they provide of the "state of the science" of stem cell biology and by framing the many questions that remain to be answered. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.Table of ContentsPreface: Jitka Ourednik, Václav Ourednik, Donald Sakaguchi, and Marit Nilsen-Hamilton. Part I: Regional Determinants of Cell Fate:. 1. Oxygen in the Cultivation of Stem Cells. By Marie Csete. 2. DNA Damage-Induced Programmed Cell Death: Potential Roles in Germ Cell Development. By Yukiko Yamada and Clark R. Coffman. . Part II: Intrinsic Determinants of Stem Cells:. 3. G Protein-Coupled Receptor Roles in Cell Migration and Cell Death Decisions: Angela R. Kamps and Clark R. Coffman. 4. Growth and Differentiation of Astrocytes and Neural Progenitor Cells on Micropatterned Polymer Films: Jennifer B. Recknor, D S. Sakaguchi, and S K. Mallapragada. 5. Cellular and Molecular Regulation of Hematopoietic and Intestinal Stem Cell Behavior: Xi C. He, Jiwang Zhang, and Linheng Li. 6. The Function of the Neuronal Proteins Shc and Huntingtin in Stem Cells and Neurons: Pharmacologic Exploitation for Human Brain Diseases: Chiara Zuccato, Luciano Conti, Erika Reitano, Marzia Tartari, and Elena Cattaneo. 7. Engineering a Dopaminergic Phenotype in Stem/Precursor Cells: Role of Nurr1, Glia-Derived Signals, and Wnts: Ernest Arenas. . Part III: Transdifferentiation:. 8. Umbilical Cord Blood-Derived Stem Cells and Brain Repair: Paul R. Sanberg, Alison E. Willing, Svitlana Garbuzova-Davis, Samuel Saporta, Guoqing Liu, Cyndy Davis Sanberg, Paula C. Bickford, Stephen K. Klasko, and Nagwa S. El-Badri. 9. Infusion of Human Umbilical Cord Blood Ameliorates Neurologic Deficits in Rats with Hemorrhagic Brain Injury: Zhenhong Nan, andrew Grande, Cyndy D. Sanberg, Paul R. Sanberg, and Walter C. Low. 10. How Wnt Signaling Affects Bone Repair by Mesenchymal Stem Cells from the Bone Marrow: Carl A. Gregory, William G. Gunn, Emigdio Reyes, Angela J. Smolarz, James Munoz, Jeffrey L. Spees, and Darwin J. Prockop. . Part IV: Stem Cell Responses to Perturbation:. 11. Human Retinal Progenitor Cells Grown as Neurospheres Demonstrate Time-Dependent Changes in Neuronal and Glial Cell Fate Potential: David M. Gamm, Aaron D. Nelson, and Clive N. Svendsen. 12. Neural Progenitor Cell Transplants into the Developing and Mature Central Nervous System: D S. Sakaguchi, S J. Van Hoffelen, S D. Grozdanic, Y H. Kwon, R H. Kardon, and M J. Young. 13. Stem Cells for Retinal Degenerative Disorders: Jason S. Meyer, Martin L. Katz, and Mark D. Kirk. 14. Magnetic Resonance Tracking of Implanted Adult and Embryonic Stem Cells in Injured Brain and Spinal Cord: Eva Syková and Pavla Jendelová. 15. The Miniature Pig as an Animal Model in Biomedical Research: Petr Vodicka, Karel Smetana, Jr., Barbora Dvoránková, Teresa Emerick, Yingzhi Z. Xu, Jitka Ourednik, Václav Ourednik, and Jan Motlík. . Part V: Reciprocal Communication between Graft and Host:. 16. Graft/Host Relationships in the Developing and Regenerating CNS of Mammals: Václav Ourednik and Jitka Ourednik. 17. Grafted Neural Stem Cells Shield the Host Environment from Oxidative Stress: Lalitha Madhavan, Václav Ourednik, and Jitka Ourednik. 18. Administration of Allogenic Stem Cells Dosed to Secure Cardiogenesis and Sustained Infarct Repair: Atta Behfar, Denice M. Hodgson, Leonid V. Zingman, Carmen Perez-Terzic, Satsuki Yamada, Garvan C. Kane, Alexey E. Alekseev, Michel Pucéat, and andre Terzic. Index of Contributors

    £90.68

  • Skeletal Biology and Medicine II: Bone and

    John Wiley and Sons Ltd Skeletal Biology and Medicine II: Bone and

    1 in stock

    Book SynopsisThe volume features current basic, clinical, and translational research on aspects of skeletal morphogenesis and remodeling in health and disease. Papers survey vital new insights into the mechanisms of bone development and restructuring, including cellular and mechanical triggers, receptors and signaling pathways. Also covered are the effects of other physiological systems and disease states, such as immune system inflammation, diabetes, infection, and cancer on musculoskeletal health. Recent findings are shaping therapeutic directions that focus on both anti-resorptive and anabolic therapies. Basic scientists, clinical investigators, and clinicians with interests spanning endocrinology, physiology, cell biology, pathology, genetics, molecular biology, rheumatology, oncology, and other areas that relate to bone development and homeostasis will find this a valuable resource for the most recent developments in skeletal biology and medicine. This volume presents manuscripts stemming from the 4th New York Skeletal Biology and Medicine Conference, held at Mount Sinai School of Medicine in New York City on April 27–30, 2011. The papers included in this volume include two of the topic areas presented at the conference; the other topic areas are included in Skeletal Biology and Medicine I. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

    1 in stock

    £59.36

  • Hematopoietic Stem Cells VIII

    John Wiley and Sons Ltd Hematopoietic Stem Cells VIII

    1 in stock

    Book SynopsisThis volume stems from the eighth international symposium and workshop entitled "Hematopoietic Stem Cells VIII" held hosted by the University of Tuebingen, Germany in the fall of 2011. The meeting was designed to bring ~30 leading scientists together to discuss the state-of-the-art in the field of hematopoietic stem cells. Topics reviewed in this volume include: differential requirements for Wnt and Notch signaling in hematopoietic versus thymic niches; hematopoietic stem cell expansion; TIM-3 as a therapeutic target for malignant stem cells in acute myelogenous leukemia; regulatory factors for hematopoietic stem cells; reprogramming factors; immune reconstitution and strategies for rebuilding of the immune system after haploidentical stem cell transplantation; zebrafish xenografts as a tool for in vivo studies on human cancer; enhancing engraftment of cord blood cells; current insights into neutrophil homeostasis; and molecular live cell bioimaging in stem cell research, among others. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. Table of ContentsPreface for Hematopoietic Stem Cells VIII vii Claudia Lengerke, Willem E. Fibbe, John E. Dick, and Lothar Kanz Basic aspects of stem cell biology Epigenetic differences between sister chromatids? 1 Peter M. Lansdorp, Ester Falconer, Jiang Tao, Julie Brind’Amour, and Ulrike Naumann Reprogramming cell fates: insights from combinatorial approaches 7 Carlos-Filipe Pereira, Ihor R. Lemischka, and Kateri Moore Molecular live cell bioimaging in stem cell research 18 Max Endele and Timm Schroeder The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems 28 Stefan Tümpel and K. Lenhard Rudolph Hematopoietic stem cell development and molecular regulation In vivo divisional tracking of hematopoietic stem cells 40 Hitoshi Takizawa and Markus G. Manz Caudal genes in blood development and leukemia 47 Claudia Lengerke and George Q. Daley Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1α in the hypoxic bone marrow niche 55 Kenichi Miharada, Göran Karlsson, Matilda Rehn, Emma Rörby, Kavitha Siva, Jörg Cammenga, and Stefan Karlsson G protein-coupled receptor crosstalk and signaling in hematopoietic stem and progenitor cells 63 Robert Möhle and Adriana C. Drost Molecular and functional characterization of early human hematopoiesis 68 Elisa Laurenti and John E. Dick Role of N-cadherin in the regulation of hematopoietic stem cells in the bone marrow niche 72 Fumio Arai, Kentaro Hosokawa, Hirofumi Toyama, Yoshiko Matsumoto, and Toshio Suda Differential requirements for Wnt and Notch signaling in hematopoietic versus thymic niches 78 Paul P.C. Roozen, Martijn H. Brugman, and Frank J.T. Staal Phenotypic and functional heterogeneity of human bone marrow- and amnion-derived MSC subsets 94 Kavitha Sivasubramaniyan, Daniela Lehnen, Roshanak Ghazanfari, Malgorzata Sobiesiak, Abhishek Harichandan, Elisabeth Mortha, Neli Petkova, Sabrina Grimm, Flavianna Cerabona, Peter de Zwart, Harald Abele, Wilhelm K. Aicher, Christoph Faul, Lothar Kanz, and Hans-Jörg Bühring Safety and efficacy of mesenchymal stromal cell therapy in autoimmune disorders 107 Maria Ester Bernardo and Willem E. Fibbe Stem cells and cancer TIM-3 as a therapeutic target for malignant stem cells in acute myelogenous leukemia 118 Yoshikane Kikushige and Koichi Akashi Zebrafish xenografts as a tool for in vivo studies on human cancer 124 Martina Konantz, Tugce B. Balci, Udo F. Hartwig, Graham Dellaire, Maya C. André, Jason N. Berman, and Claudia Lengerke Translational research Hematopoietic stem cell expansion: challenges and opportunities 138 Marta A. Walasek, Ronald van Os, and Gerald de Haan Enhancing engraftment of cord blood cells via insight into the biology of stem/progenitor cell function 151 Hal E. Broxmeyer Immune reconstitution and strategies for rebuilding the immune system after haploidentical stem cell transplantation 161 Lena Oevermann, Peter Lang, Tobias Feuchtinger, Michael Schumm, Heiko-Manuel Teltschik, Patrick Schlegel, and Rupert Handgretinger Current insights into neutrophil homeostasis 171 Stefanie Bugl, Stefan Wirths, Martin R. Müller, Markus P. Radsak, and Hans-Georg Kopp Prospects and challenges of induced pluripotent stem cells as a source of hematopoietic stem cells 179 Dirk W. van Bekkum and Harald M.M. Mikkers

    1 in stock

    £99.00

  • Neuroimunomodulation in Health and Disease I:

    John Wiley and Sons Ltd Neuroimunomodulation in Health and Disease I:

    10 in stock

    Book SynopsisThis is one of two Annals volumes that present papers by speakers at the 8th International Society for Neuroimmodulation Congress held in Dresden, Germany, October 2011. The papers focus on interactions among the immune, endocrine, and nervous systems that occur at multiple levels, from intracellular pathways by immune and neuro-endocrine mediators, to the exchange of information between the three systems that results in physiologic and adaptive effects. In certain instances, however, these interactions may be unbalanced or even disrupted, which can contribute to pathology, and aspects of such pathobiology are presented in some of the contributions. This volume focuses on the basic science of immune-neuro-endocrine interactions.Table of ContentsForeword for Neuroimmunomodulation in Health and Disease Adriana del Rey C. Jane Welsh Markus J. Schwarz Hugo O. Besedovsky vii Expression and functions of μ-opioid receptors and cannabinoid receptors type 1 in T lymphocytes Jürgen Kraus 1 Reconciling neuronally and nonneuronally derived acetylcholine in the regulation of immune function Koichiro Kawashima Takeshi Fujii Yasuhiro Moriwaki Hidemi Misawa Kazuhide Horiguchi 7 T cells affect central and peripheral noradrenergic mechanisms and neurotrophin concentration in the spleen and hypothalamus Jamela Jouda Johannes Wildmann Martin Schäfer Eduardo Roggero Hugo O. Besedovsky Adriana del Rey 18 Sympathetic nerve fiber repulsion: testing norepinephrine, dopamine, and 17β-estradiol in a primary murine sympathetic neurite outgrowth assay Susanne Klatt Alexander Fassold Rainer H. Straub 26 Glucocorticoid-catecholamine interplay within the composite thymopoietic regulatory network Ivan Pilipoviæ Katarina Radojeviæ Milica Perišiæ Gordana Leposaviæ 34 Presentation of neuroendocrine self in the thymus: a necessity for integrated evolution of the immune and neuroendocrine systems Vincent Geenen 42 Growth hormone modulates migration of thymocytes and peripheral T cells Wilson Savino Salete Smaniotto Daniella Arêas Mendes-da-Cruz Mireille Dardenne 49 Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction Marni N. Silverman Esther M. Sternberg 55 Hsp72, inflammation, and aging: causes, consequences, and perspectives Eduardo Ortega María Elena Bote Hugo Oscar Besedovsky Adriana del Rey 64 Regulation of intestinal morphology and GALT by pituitary hormones in the rat Luz María Cárdenas-Jaramillo Andrés Quintanar-Stephano Rosa Adriana Jarillo-Luna Víctor Rivera-Aguilar Gabriela Oliver-Aguillón Rafael Campos-Rodríguez Kalman Kovacs Istvan Berczi 72 Transforming growth factor-beta inhibits the expression of clock genes Heidemarie Gast Sonja Gordic Saskia Petrzilka Martin Lopez Andreas Müller Anton Gietl Christoph Hock Thomas Birchler Adriano Fontana 79 Role of interleukin-6 in stress, sleep, and fatigue Nicolas Rohleder Martin Aringer Matthias Boentert 88 Role of sleep in the regulation of the immune system and the pituitary hormones Beatriz Gómez-González Emilio Domínguez-Salazar Gabriela Hurtado-Alvarado Enrique Esqueda-Leon Rafael Santana-Miranda Jose Angel Rojas-Zamorano Javier Velázquez-Moctezuma 97 Erratum for Ann. N. Y. Acad. Sci. 1257: 125-132 107

    10 in stock

    £56.52

  • The Renaissance of Cancer Immunotherapy: The 7th

    John Wiley and Sons Ltd The Renaissance of Cancer Immunotherapy: The 7th

    10 in stock

    Book SynopsisThis Annals volume includes invited short reviews on topics presented at the 7th International Cancer Vaccine Symposium “Renaissance of Cancer Immunotherapy”, held September 9-11, 2012 in Florence, Italy. The papers cover the latest progress in basic immunology research and its translation to cancer patients. The meeting and papers pay tribute to the successes in the last few years that have led to the approval of new immunotherapies and the awarding of the Nobel Prize in medicine to three immunologists. The symposium is dedicated to one of these recipients, Dr. Ralph Steinman who discovered dendritic cells, immune cells that are vital in immune responses and immunotherapies for cancer. NOTE: Annals volumes are available for sale as individual books or as a journal. For more information on institutional journal subscriptions, please visit: http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632 ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information on becoming a member.Table of ContentsIntroduction to The Renaissance of Cancer Immunotherapy vOlivera J. Finn and Gerold Schuler Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy 1Matthews D. Vesely and Robert D. Schreiber Cell-extrinsic effects of the tumor unfolded protein response on myeloid cells and T cells 6Maurizio Zanetti Immunotherapy in preneoplastic disease: targeting early procarcinogenic inflammatory changes that lead to immune suppression and tumor tolerance 12Bridget Keenan and Elizabeth M. Jaffee Integration of epidemiology, immunobiology, and translational research for brain tumors 17Hideho Okada, Michael E. Scheurer, Saumendra N. Sarkar, and Melissa L. Bondy Human dendritic cells subsets as targets and vectors for therapy 24Eynav Klechevsky and Jacques Banchereau Dendritic cell immunotherapy 31Rachel Lubong Sabado and Nina BhardwajMolecular programming of steady-state dendritic cells: impact on autoimmunity and tumor immune surveillance 46Dylan J. Johnson and Pamela S. Ohashi Preventing cancer by targeting abnormally expressed self-antigens: MUC1 vaccines for prevention of epithelial adenocarcinomas 52Pamela L. Beatty and Olivera J. Finn Immunological control of cell cycle aberrations for avoidance of oncogenesis: the case of tetraploidy 57Laura Senovilla, Lorenzo Galluzzi, Maria Castedo, and Guido Kroemer Ongoing adaptive immune responses in the microenvironment of melanoma metastases 62Nicolas van Baren and Pierre G. Coulie Main features of human T helper 17 cells 66Francesco Annunziato, Lorenzo Cosmi, Francesco Liotta, Enrico Maggi, and Sergio Romagnani In silico modeling of cancel cell dissemination and metastasis 71Lu-En Wai, Vipin Narang, Alexandre Gouaillard, Lai Guan Ng, and Jean-Pierre Abastado Common pathways to tumor rejection 75Ena Wang, Davide Bedognetti, Sara Tomei, and Francesco M. Marincola Cancer-induced immunosuppressive cascades and their reversal by molecular-targeted therapy 80Yutaka Kawakami, Tomonori Yaguchi, Hidetoshi Sumimoto, Chie Kudo-Saito, Nobuo Tsukamoto. Tomoko Iwata-Kajihara, Shoko Nakamura, Hiroshi Nishio, Ryosuke Satomi, Asuka Kobayashi, Mayuri Tanaka, Jeong Hoon Park, Hajime Kamijuku, Takahiro Tsujikawa, and Naoshi Kawamura

    10 in stock

    £104.50

  • Roeser's Audiology Desk Reference

    Thieme Medical Publishers Inc Roeser's Audiology Desk Reference

    1 in stock

    Book SynopsisAudiologists are often pressed for time and need an up-to-date reference for quick consultation in their daily practice. Roeser's Audiology Desk Reference, Second Edition, is an accessible resource containing all the latest facts, figures, diagrams, and standards that are essential to an audiologist's practice. Key Features: Covers relevant topics such as anatomy and physiology, audiologic and vestibular testing, instruments and procedures, hearing conservation, and much more! Includes thousands of practical facts, figures, and tables for use in daily practice Contains valuable information on all aspects of audiology diagnosis and treatment Compiled and edited by Dr. Roeser along with four seasoned experts in the audiology profession This invaluable clinical guide will be the reference of choice for all busy practitioners and students in audiology and speech-language pathology.Trade ReviewPraise for the best-selling first edition:" fills a much needed gap in audiological literature, providing a source of essential facts, figures and diagrams " the information is precise and easy to read, while the contents and index pages are also very detailed, making it easy to locate information." -- Journal of Otolaryngology

    1 in stock

    £76.95

  • Total Otolaryngology-Head and Neck Surgery

    Thieme Medical Publishers Inc Total Otolaryngology-Head and Neck Surgery

    1 in stock

    Book SynopsisAn essential reference on otolaryngology - head and neck surgery This comprehensive otolaryngology reference presents a consistent approach to the diagnosis and treatment of head and neck disorders. It provides thorough coverage of basic science topics as well as concise, practical information on clinical topics, such as radiographic imaging of common clinical presentations, deep neck infections, transoral robotic surgery, surgery of the aging face, lasers in laryngology, and much more. Key Features: Opening section on emergency management containing key information residents need for emergency room rotations An expanded section on head and neck pathology Highlights provided in "roundsmanship" section of clinical chapters, ensuring that residents will have the answers to tough questions encountered on rounds High-quality illustrations help readers visualize information presented in the text Selected key references that provide in-depth details on specific topics This concise, practical reference is designed to be the main otolaryngology text that residents and fellows will use on a daily basis and the principal text otolaryngologists will use for board recertification review.Table of ContentsSection 1. Emergency Management 1 Head and Neck Emergencies 2 Otologic Emergencies 3 Pediatric ENT Emergencies 4 Facial Plastic and Reconstructive Surgery Emergencies 5 Rhinologic Emergencies 6 Laryngologic Emergencies 7 Emergency Airway Management and Tracheotomy Section 2. General Otolaryngology 8 Head and Neck Anatomy 9 The Complete Otolaryngology Physical Examination 10 Radiology of the Head and Neck 11 Radiographic Imaging of Common Clinical Presentations in Otolaryngology–Head and Neck Surgery 12 General Anesthesia and Anesthetic Considerations for Otolaryngologic Surgery 13 Infectious Diseases of the Oral Cavity, Pharynx, and Larynx 14 Antimicrobial Therapy for Head and Neck Infections 15 Evaluation and Management of Deep Neck Space Infections 16 Evaluation and Management of Hearing Loss in Adults 17 Evaluation and Management of Otalgia 18 Obstructive Sleep Apnea 19 Head and Neck Manifestations of Systemic Diseases Section 3. Head and Neck Surgery Subsection 3a. Overview of Head and Neck Surgery 20 Epidemiology of Head and Neck Cancers 21 Head and Neck Histopathology 22 The Role of Radiation Therapy in the Management of Head and Neck Cancer Subsection 3b. The Upper Aerodigestive Tract 23 Diseases and Neoplasms of the Oral Cavity 24 Diseases and Neoplasms of the Pharynx and Esophagus 25 Diseases and Neoplasms of the Larynx 26 Surgery of the Laryngopharynx 27 Transoral Robotic Surgery Subsection 3c. Surgery of the Neck 28 Nonneoplastic Salivary Gland Diseases 29 Benign Neoplasms of the Salivary Glands 30 Malignant Neoplasms of the Salivary Glands 31 Diseases and Neoplasms of the Thyroid 32 Parathyroid Hormone, Vitamin D, and Bone Mineral Metabolism 33 Surgical Techniques for the Management of Thyroid and Parathyroid Diseases 34 Soft-Tissue Tumors of the Head and Neck 35 Principles and Techniques of Neck Dissection 36 Evaluation and Management of the Solitary Neck Mass 37 Blunt and Penetrating Neck Injuries Section 4. Facial Plastic and Reconstructive Surgery Subsection 4a. Introduction to Facial Plastic and Reconstructive Surgery 38 Facial Analysis 39 Wound Healing 40 Local and Regional Anesthesia for Facial Plastic Surgery Subsection 4b. Management of Facial Trauma 41 Facial Soft-Tissue Trauma 42 Maxillofacial Trauma 43 Scar Revision Subsection 4c. Head and Neck Dermatology 44 Rosacea 45 Common Facial Skin Lesions 46 Mohs Micrographic Surgery Subsection 4d. Methods in Facial Reconstruction 47 Grafts in Head and Neck Surgery 48 Reconstruction of Facial Soft-Tissue Defects 49 Myocutaneous and Free Flap Reconstruction 50 Tissue Expansion 51 Treatment of Facial Paralysis 52 Correction of Congenital Auricular Deformities Subsection 4e. Aesthetic Surgery of the Nose 53 Primary Rhinoplasty 54 Revision Rhinoplasty 55 Special Considerations in Rhinoplasty Subsection 4f. Rejuvenation of the Aging Face 56 Surgical Treatment of the Aging Face 57 Blepharoplasty 58 Facial Implants 59 Management of Aging Skin 60 Facial Soft-Tissue Fillers and Neuromodulators Section 5. Pediatric Otolaryngology Subsection 5a. Overview of Pediatric Otolaryngology 61 The Evolution of Pediatric Otolaryngology–Head and Neck Surgery 62 The Otolaryngologic Examination of Children 63 Special Considerations in Pediatric Anesthesiology Subsection 5b. Pediatric Otology 64 Common Genetic Syndromes in Otolaryngology 65 Congenital Malformations of the External and Middle Ear 66 Evaluation, Management, and Special Techniques in Pediatric Otology Subsection 5c. Pediatric Rhinology 67 Pediatric Nasal Disorders 68 Pediatric Sinus Disorders Subsection 5d. Pediatric Aerodigestive Disorders 69 Pharyngeal and Esophageal Disorders in Children 70 Pediatric Obstructive Sleep Apnea 71 Cleft Lip and Palate 72 Airway Disorders in Children Subsection 5e. The Pediatric Neck 73 Diseases and Disorders of the Pediatric Neck Section 6. Laryngology Subsection 6a. Laryngopharyngeal Anatomy and Physiology 74 Laryngeal Anatomy 75 Vocal Physiology 76 Pharyngeal Anatomy 77 Physiology of Swallowing Subsection 6b. Laryngopharyngeal Evaluation 78 Voice Evaluation 79 Laryngovideostroboscopy 80 Laryngeal Electromyography 81 Diagnostic Testing for Dysphagia 82 Evaluation and Management of the Hoarse Patient Subsection 6c. Laryngopharyngeal Pathology and Management 83 Laryngitis 84 Systemic Diseases of the Larynx 85 Unilateral Vocal Fold Immobility 86 Bilateral Vocal Fold Paralysis 87 Laryngopharyngeal (Airway) Reflux 88 Neurologic Disorders of the Larynx 89 Spasmodic Dysphonia 90 Benign Lesions of the Larynx 91 Adult Laryngotracheal Stenosis 92 Laryngeal Trauma 93 Instrumentation and Techniques of Phonomicrosurgery 94 Voice Therapy 95 Lasers in Laryngology Subsection 6d. Bronchoesophagology 96 Tracheo-Esophageal Puncture 97 Evaluation and Management of Esophageal Disorders 98 Management of Oropharyngeal Dysphagia 99 Evaluation and Management of Tracheobronchial Infections and Masses 100 Tracheobronchoscopy and Esophagoscopy Section 7. Rhinology Subsection 7a. Rhinologic Anatomy, Physiology, and Evaluation 101 Evaluation of the Rhinosinusitis Patient and Surgical Considerations 102 Anatomy and Physiology of the Nose and Paranasal Sinuses 103 Nasal Immunity 104 Olfaction and Taste Disorders Subsection 7b. Infectious and Non-Infectious Disorders of the Nose 105 Benign Nasal Obstruction 106 Allergic and Nonallergic Rhinitis 107 Medical Management of Acute and Chronic Sinusitis 108 Surgical Treatment of Sinusitis Subsection 7c. Neoplastic Disorders of the Nose, Sinuses, and Anterior Skull Base 109 Tumors of the Nose and Paranasal Sinuses 110 Surgical Techniques for the Anterior Skull Base Section 8. Otology Subsection 8a. Anatomy, Physiology, and Testing of the Ear 111 Anatomy and Embryology of the Ear 112 Auditory Function and Dysfunction 113 Equilibrium Function and Dysfunction 114 Diagnostic Audiology 115 Radiology of the Temporal Bone Subsection 8b. Disorders of the External and Middle Ear 116 Diseases of the External Ear 117 Conditions of the Middle Ear and Mastoid 118 Surgery for Chronic Ear Disease Subsection 8c. Disorders of the Inner Ear 119 Syndromic and Nonsyndromic Hearing Loss 120 Noise-Induced Hearing Loss and Hearing Protection 121 Sudden Idiopathic Sensorineural Hearing Loss 122 Ototoxicity 123 Auditory Neuropathy 124 Tinnitus 125 Retrocochlear Hearing Disorders Subsection 8d. Hearing Restoration 126 Middle Ear Implants 127 Otosclerosis and Stapedectomy 128 Baha and Other Osseointegrated Temporal Bone Implants 129 Cochlear Implantation Subsection 8e. Management of Disequilibrium 130 Vestibular Pathology: Evaluation and Clinical Syndromes 131 Management of the Patient with Chronic Dizziness Subsection 8f. Facial Paralysis 132 Diagnostic Assessment and Management of Acute Facial Palsy Subsection 8g. Neoplasms of the Temporal Bone, Middle and Posterior Fossae 133 Anatomy of the Skull Base and Infratemporal Fossa 134 Posterior Skull Base Diseases and Surgery 135 Middle Cranial Fossa Anatomy and Surgery 136 Vascular Tumors of the Skull Base and Petrous Apex Lesions 137 Stereotactic Radiation Treatment for Benign Tumors of the Posterior Cranial Fossa 138 Lesions of the Petrous Apex

    1 in stock

    £73.15

  • Differential Diagnosis in Musculoskeletal MR

    Thieme Medical Publishers Inc Differential Diagnosis in Musculoskeletal MR

    1 in stock

    Book SynopsisThe definitive guide to MRI for musculoskeletal abnormalities Differential Diagnosis in Musculoskeletal MRI is a unique desk reference offering extensive descriptions of MRI findings that enable radiologists to more easily diagnose a wide range of musculoskeletal conditions. The authors have placed the most essential content covering etiologic, clinical, and pathological aspects in tabular format to assist readers in quickly and efficiently obtaining the information they need. Features: More than 2,000 state-of-the-art images covering the features for both common and rare musculoskeletal conditions Authors provide a practical approach to MRI evaluation and differential diagnosis selection Differential diagnosis tables are based on anatomic locations of lesions This practical reference is an invaluable tool that practicing radiologists, residents, and fellows will use to diagnose both common and rare lesions as well as other disorders of the musculoskeletal system. It is an excellent guide for use in daily practice as well as a comprehensive exam preparation tool.Table of Contents1 Introduction to Magnetic Resonance Imaging for Evaluation of Musculoskeletal Abnormalities 2 The Shoulder 3 The Elbow 4 The Wrist 5 The Hand 6 The Hip 7 The Knee 8 The Ankle and Foot 9 Magnetic Resonance Imaging of Bone and Soft Tissue Tumors and Tumor-Like Lesions: An Overview 10 Lesions Involving Bones 11 Lesions within Joints 12 Lesions Involving the Soft Tissues

    1 in stock

    £137.75

  • Differential Diagnosis in Neuroimaging: Brain and

    Thieme Medical Publishers Inc Differential Diagnosis in Neuroimaging: Brain and

    4 in stock

    Book SynopsisAuthored by renowned neuro-radiologist Steven P. Meyers, Differential Diagnosis in Neuroimaging: Brain and Meninges is a stellar guide for identifying and diagnosing brain pathologies based on location and neuroimaging results. The succinct text reflects more than 25 years of hands-on experience gleaned from advanced training and educating residents and fellows in radiology, neurosurgery, and neurology. The high-quality MRI, CT, PET, PET/CT, conventional angiography, and X-ray images have been collected over Dr. Meyers's lengthy career, presenting an unsurpassed visual learning tool. The distinctive 'three-column table plus images' format is easy to incorporate into clinical practice, setting this book apart from larger, disease-oriented radiologic tomes. The layout enables readers to quickly recognize and compare abnormalities based on high-resolution images. Key Highlights Tabular columns organized by anatomical abnormality include brain imaging findings and a summary of key clinical data that correlates to the images Comprehensive imaging of the brain, ventricles, meninges, and neurovascular system in both children and adults, including congenital/developmental anomalies and acquired disease More than 1,900 figures illustrate the radiological appearance of intracranial lesions, masses, neurodegenerative disorders, ischemia and infarction, and more This visually rich resource is a must-have diagnostic tool for radiologists, neurosurgeons, and neurologists, and residents and fellows. The highly practical format makes it ideal for daily rounds, as well as a robust study guide for physicians preparing for board exams.Trade ReviewThis is a highly valuable book that contains a tremendous amount of information in words and pictures. It should be a must-have guide and reference manual for anyone involved in neurology and neurosurgery. -- BIZ INDIA ...an outstanding way to learn imaging anatomy and corresponding diseases...This [series] is a highly desirable set of books and would be a valuable addition to any neuroradiologist's personal collection, and certainly to any departmental or sectional library. -- AJNR BlogTable of Contents1 Brain (Intra-Axial Lesions) 2 Ventricles and Cisterns 3 Extra-Axial Lesions 4 Meninges 5 Vascular Abnormalities

    4 in stock

    £133.95

  • Neurosurgical Infectious Disease: Surgical and

    Thieme Medical Publishers Inc Neurosurgical Infectious Disease: Surgical and

    1 in stock

    Book SynopsisRapid diagnosis and treatment are crucial to successful outcomes in infections involving the central nervous system, which can cause significant neurological morbidity and mortality. Neurosurgical Infectious Disease: Surgical and Nonsurgical Management is a comprehensive guide that gives surgeons the core knowledge they need to diagnose, treat, and prevent infectious diseases of the central nervous system. Key Features: Emphasizes newer surgical techniques, including: endoscopy, neuronavigation, and intraoperative guidance Covers contemporary radiologic diagnostic techniques and provides excellent imaging examples Includes chapters on antibiotic prophylaxis, intracranial infection, and the infection of implanted devices This excellent neurosurgical reference will be an essential part of the armamentarium used by neurosurgeons and infectious disease specialists in their daily practice.

    1 in stock

    £101.65

  • A Dictionary of Hearing

    Thieme Medical Publishers Inc A Dictionary of Hearing

    1 in stock

    Book SynopsisA Dictionary of Hearing is a comprehensive reference that defines terms used in audiology, ENT, and related areas. This dictionary covers a wide range of terms in audiology and will be very useful to students and professionals in the field of hearing, including audiologists, nurses and doctors, teachers of the deaf, and speech and language therapists. Key Features: Contains over 4,000 common and uncommon audiological terms with clear meanings Includes the etymology of words, providing a historical context for students Entries have the breadth and depth of definition that students and professionals need This dictionary is an essential resource that all professionals in the field of audiology will want to have at their fingertips.Table of ContentsGuide to the Dictionary Common Acronyms Chapters A-Z

    1 in stock

    £36.57

  • Encyclopedia of Heart Diseases

    Humana Press Inc. Encyclopedia of Heart Diseases

    Book SynopsisThe fully revised second edition of the Encyclopedia of Heart Diseases is an ideal resource for practicing clinicians and researchers. Available in print, online, and with dual access, it is a clear and comprehensive aggregation of the most crucial information and essential data on cardiovascular diseases and therapeutics.Comprised of over 95 entries with regular online updates, the Encyclopedia of Heart Diseases is fully referenced, and major points of interests are hyperlinked to complementary sections. Each entry is logically and superbly written, providing accurate core knowledge of pathogenesis, pathophysiology, clinical features, diagnostic techniques, and management strategies. Specific detail is paid to technological advances in imaging and diagnostics. Therapy focused entries give powerful insights into not only prescribing drug regimens, but also into the controversies surrounding their use.This major reference work is invaluable for all those involved in the care of cardiovascular patients. From the front-line practitioner to the basic science researcher to the student in training, the Encyclopedia of Heart Diseases offers an astute authoritative guide to navigating an immense body of fascinating information. From the trainee to the internist and cardiologist, all will find it useful. It is an essential resource for medical libraries and academic institutions worldwide. From the Foreword:So, what would we want from an encyclopedia on heart disease? Ideally, a book would be comprehensive, yet concise, and be practically oriented, and explain pathophysiology and treatment. In addition, it should be accessible online so that it can be accessed at the bedside or anywhere.Dr. Khan has written exactly such a book. Encyclopedia of Heart Diseases is comprehensive, yet concise, and very practically oriented. Importantly, it takes a step-by-step approach, walking the reader through a thorough pathophysiology of conditions, their evaluation and treatment. For therapies, he provides the mechanism of the drug, its doses, side effects and clinical efficacy....A terrific online resource with all the information you need!- Christopher P. Cannon, MD, TIMI Study Group, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USATable of ContentsOver 95 entries, including entries such as• ACE Inhibitors• Beta Blockers Hypertension Controversy• Blood Pressure• Clinical Trials• Diabetes Caused by Diuretics and Beta Blockers• Erectile Dysfunction and the Heart• Marfan Syndrome• Murmurs and Heart Disease• Pulmonary Hypertension• Women and Heart DiseaseWith over 255 figures, including echocardiographic animations

    £522.49

  • Berkowitz's Pediatrics: A Primary Care Approach

    American Academy of Pediatrics Berkowitz's Pediatrics: A Primary Care Approach

    2 in stock

    Book SynopsisThe reference of choice for pediatricians, residents and medical students, the newly revised and expanded 6th edition provides clear, practice-oriented guidance on the core knowledge in pediatrics. Edited by a leading primary care authority with more than one hundred contributors, the 6th edition provides comprehensive coverage of hundreds of topics ranging from temper tantrums and toilet training to adolescent depression and suicide. More than 155 (including 5 brand new) clinical chapters review pertinent epidemiology and pathophysiology, then give concise guidelines on what symptoms to look for, what alternative diagnoses to consider, what tests to order, and how to treat your patient. New in the 6th edition All chapters have been reviewed and updated to address current issues. Five new chapters are included on the following: Health Systems Science Population Health for Pediatricians Social Determinants of Health: Principles Adverse Childhood Experiences: Trauma Informed Care Commercially Exploited Children and Human Trafficking Student worksheets corresponding to each chapter's case study questions will be posted online in a user-friendly format so that they can be completed in preparation of discussions. Case study questions have been enhanced; resources, revised; and acronyms added as an appendix. This edition is completely reorganized into 15 sections using a systems-based approach. Trade ReviewA 2023 Doody’s Core Title®Table of Contents Preface Section I: Primary Care: Skills and Concepts Chapter 1. Primary Care: Introduction Chapter 2. Talking with Parents Chapter 3. Talking with Children Chapter 4. Talking with Adolescents Chapter 5. Telephone Management and E-Medicine Chapter 6. Informatics Chapter 7. Counseling Families about Internet Use Chapter 8. Cultural Competency Issues in Pediatrics Chapter 9. Global Child Health Chapter 10. Child Advocacy Section II: Principles of Health Care and Pediatric Management Chapter 11. Health Systems Science Chapter 12. Population Health for Pediatricians Chapter 13. Principles of Pediatric Therapeutics Chapter 14. Pediatric Pain and Symptom Management Chapter 15. Complementary and Integrative Medicine in Pediatric Primary Care Chapter 16. Principles of Pediatric Surgery Chapter 17. Image Gently Approach to Pediatric Imaging Chapter 18. Simulation in Pediatric Health Care Chapter 19. Pediatric Hospital Medicine Chapter 20. Pediatric Genomic Medicine Chapter 21. Principles of Quality Improvement: Improving Health Care for Pediatric Patients Chapter 22. Pediatric Palliative Care: Principles and Practice Section III: Health Maintenance and Anticipatory Guidance Chapter 23. Neonatal Examination and Nursery Visit Chapter 24. Maternal Perinatal Mood and Anxiety Disorders: The Role of the Pediatrician Chapter 25. Newborn Screening Chapter 26. Caring for Twins and Higher-Order Multiples Chapter 27. Male Circumcision Chapter 28. Nutritional Needs Chapter 29. Breastfeeding Chapter 30. Sleep: Normal Patterns and Common Disorders Chapter 31. Oral Health and Dental Disorders Chapter 32. Normal Development and Developmental Surveillance, Screening, and Evaluation Chapter 33. Speech and Language Development: Normal Patterns and Common Disorders Chapter 34. Literacy Promotion in Pediatrics Chapter 35. Gifted Children Chapter 36. Children and School: A Primer for the Practitioner Chapter 37. Immunizations Chapter 38. Health Maintenance in Older Children and Adolescents Chapter 39. Health Care of International Adoptees Chapter 40. Health Care Needs of Children in Foster Care Chapter 41. Working with Immigrant Children and Their Families Chapter 42. Well Child Care for Children with Trisomy 21 (Down Syndrome) Chapter 43. Well-Child Care for Preterm Infants Chapter 44. Care of Children with Special Health Care Needs Chapter 45. Injury Prevention Chapter 46. Fostering Self-Esteem Chapter 47. Sibling Rivalry Chapter 48. Toilet Training Chapter 49. Crying and Colic Chapter 50. Discipline Chapter 51. Temper Tantrums Chapter 52. Breath-Holding Spells Chapter 53. Fears, Phobias, and Anxiety Chapter 54. Thumb Sucking and Other Habits Chapter 55. Enuresis Chapter 56. Encopresis Section IV: Adolescent Health Chapter 57. Culturally Competent Care for Diverse Populations: Sexual Orientation and Gender Expression Chapter 58. Reproductive Health Chapter 59. Vaginitis Chapter 60. Sexually Transmitted Infections Chapter 61. Menstrual Disorders Chapter 62. Disorders of the Breast Chapter 63. Substance Use/Abuse Chapter 64. Eating Disorders Chapter 65. Body Modifications: Tattooing and Body Piercing Chapter 66. Depression and Suicide in Adolescents Section V: Acute and Emergent Problems Chapter 67. Fever and Bacteremia Chapter 68. Emerging Infectious Diseases Chapter 69. Febrile Seizures Chapter 70. Respiratory Distress Chapter 71. Stridor and Croup Chapter 72. Sudden Unexpected Infant Death and Brief Resolved Unexplained Events Chapter 73. Syncope Chapter 74. Shock Chapter 75. Approach to the Traumatized Child Chapter 76. Abdominal Trauma Chapter 77. Acute Abdomen (Appendicitis) Chapter 78. Head Trauma Chapter 79. Increased Intracranial Pressure Chapter 80. Management of Dehydration in Children: Fluid and Electrolyte Therapy Chapter 81. Acute Kidney Injury Chapter 82. Ingestions: Diagnosis and Management Chapter 83. Disaster Preparedness Chapter 84. Approach to the Child With Dysmorphism Section VI: Head, Neck, and Respiratory System Chapter 85. Craniofacial Anomalies Chapter 86. Common Oral Lesions Chapter 87. Otitis Media Chapter 88. Hearing Impairments Chapter 89. Sore Throat Chapter 90. Nosebleeds Chapter 91. Strabismus Chapter 92. Infections of the Eye Chapter 93. Excessive Tearing Chapter 94. Neck Masses Chapter 95. Allergic Disease Chapter 96. Wheezing and Asthma Chapter 97. Cough Section VII: Hematologic Disorders Chapter 98. Anemia Chapter 99. Bleeding Disorders Chapter 100. Lymphadenopathy Section VIII: Cardiovascular System Chapter 101. Heart Murmurs Chapter 102. Palpitations Chapter 103. Cyanosis in The Newborn Chapter 104. Congestive Heart Failure Chapter 105. Chest Pain Chapter 106. Hypertension Section IX: Genitourinary Disorders Chapter 107. Disorders of Sexual Differentiation Chapter 108. Inguinal Lumps and Bumps Chapter 109. Hematuria Chapter 110. Proteinuria Chapter 111. Nephrotic Syndrome Chapter 112. Urinary Tract Infections Section X: Orthopedic Disorders Chapter 113. Developmental Dysplasia of the Hip Chapter 114. In-toeing and Out-toeing: Rotational Problems of the Lower Extremity Chapter 115. Angular Deformities of the Lower Extremity: Bowlegs and Knock-Knees Chapter 116. Orthopedic Injuries and Growing Pains Chapter 117. Sports-Related Acute Injuries Chapter 118. Evaluation of Limp Chapter 119. Musculoskeletal Disorders of the Neck and Back Section XI: Gastrointestinal Disorders Chapter 120. Vomiting Chapter 121. Gastroesophageal Reflux Chapter 122. Gastrointestinal Bleeding Chapter 123. Diarrhea Chapter 124. Constipation Chapter 125. Abdominal Pain Chapter 126. Jaundice Chapter 127. Viral Hepatitis Section XII: Neuropsychiatric Disorders Chapter 128. Hypotonia Chapter 129. Headaches Chapter 130. Tics Chapter 131. Seizures and Epilepsy Chapter 132. Autism Spectrum Disorder Chapter 133. Attention-Deficit/Hyperactivity Disorder Chapter 134. Psychopharmacology in Children Section XIII: Dermatologic Disorders Chapter 135. Acne Chapter 136. Disorders of the Hair and Scalp Chapter 137. Diaper Dermatitis Chapter 138. Papulosquamous Eruptions Chapter 139. Morbilliform Rashes Chapter 140. Vesicular Exanthems Section XIV: Social Determinants of Health Chapter 141. Social Determinants of Health: Principles Chapter 142. Adverse Childhood Experiences: Trauma Informed Care Chapter 143. Commercially Exploited Children and Human Trafficking Chapter 144. Physical Abuse Chapter 145. Sexual Abuse Chapter 146. Failure to Thrive Chapter 147. Fetal Alcohol Syndrome Chapter 148. Infants of Substance Using Mothers Chapter 149. Divorce Chapter 150. School-Related Violence and Bullying Chapter 151. Intimate Partner Violence Section XV: Chronic Diseases of Childhood and Adolescence Chapter 152. Cancer in Children Chapter 153. Chronic Kidney Disease Chapter 154. Diabetes Mellitus Chapter 155. Childhood Obesity Chapter 156. Juvenile Idiopathic Arthritis and Benign Joint Pains of Childhood Chapter 157. Autoimmune Connective Tissue Diseases Appendix: List of Acronyms

    2 in stock

    £98.40

  • John Wiley & Sons NRP407 NRP Key Behavioral Skills Poster

    10 in stock

    10 in stock

    £26.21

  • Minimally Invasive Glaucoma Surgery: A Practical

    Thieme Medical Publishers Inc Minimally Invasive Glaucoma Surgery: A Practical

    2 in stock

    Book SynopsisThe most comprehensive, up-to-date textbook on Minimally Invasive Glaucoma Surgery Glaucoma affects millions of people worldwide and is the second leading cause of blindness. Major advances in innovative surgical techniques, collectively termed minimally invasive glaucoma surgery (MIGS), have revolutionized the field. These groundbreaking ophthalmic surgery approaches are effective, are not bleb-dependent, and they result in fewer complications. Authored by a Who's Who of prominent experts in the MIGS movement, this book represents the most comprehensive book written to date on the subject. Leading glaucoma surgeons offer unique perspectives and experience gleaned from developing and mastering these state-of-the-art techniques. The first four sections discuss fundamental concepts of eye anatomy and structure, outflow implications, and aqueous production. The remaining sections cover the latest cutting-edge procedures elucidated through text descriptions and case studies, with the final two chapters offering insights into how to best incorporate MIGS into your practice and possibilities for combining MIGS procedures to expand the treatment algorithm for patients with more moderate to advanced disease. Meticulous, step-by-step drawings, photos, and surgical videos further delineate advanced MIGS techniques. Select State-of-the-Art Procedures Trabecular Outflow Trabectome Gonioscopic Assisted Transluminal Trabeculotomy (GATT) Ab Interno 360 Degree Goniotomy (TRAB360) iStent Hydrus Eximer Laser Trabeculoplasty Uveoscleral Outflow Canaloplasty SOLX Gold Shunt CyPass iStent Supra Aqueous Humor Reduction Endoscopic Cyclophotocoagulation Transconjunctival Filtration Aquesys XEN Gel Stent InnFocus Microshunt This remarkable resource will enable ophthalmologists to incorporate cutting-edge MIGS into practice. It is a must have for any clinician who endeavors to advance the treatment of glaucoma.Table of Contents1 New Options in the Treatment of Glaucoma Section I Eye Anatomy and Physiology 1A Trabecular Outflow 2 Structure and Mechanisms of Trabecular Outflow 3 How Does Trabecular Bypass Affect the Relationship Between Schlemm's Canal Pressure and Episcleral Venous Pressure? 4 What Role Do Collector Channels Play in Determining Outcomes of Trabecular Bypass Surgery? 5 Segmental Aqueous Outflow and Trabecular Bypass 6 Pulsatile Aqueous Outflow Observations to Guide Glaucoma Surgery 7 The Effect of Ultrasound on Aqueous Dynamics 8 Sonic Effect on Aqueous Outflow IB Uveoscleral Outflow 9 Structure and Mechanisms of Uveoscleral Outflow 10 What Is the Suprachoroidal Space and Can It Scar? 11 Suprachoroidal Drainage—Centenarian Progress: An Inventor's Perspective 12 Do Prostaglandins Make Uveoscleral Outflow More Pressure Dependent? IC Aqueous Production 13 Structure and Mechanisms of Aqueous Production 14 How Does Cyclodestruction Affect Diurnal Intraocular Pressure Variation? 15 How Does Cyclodestruction Affect the Blood–Aqueous Barrier? 16 What Roles Do Posterior Ciliary Processes and Pars Plana Play in Aqueous Formation? ID Subconjunctival Filtration 17 Structure and Mechanisms of Subconjunctival Outflow 18 Does Subconjunctival Filtration Affect Intraocular Pressure Fluctuation? 19 Benzalkonium Chloride and Outflow Resistance 20 The Fibroblast and Glaucoma Surgery 21 Imminent Replacements for Trabeculectomy Section II Clinical Procedures IIA Trabecular Outflow Procedures 22 Phacoemulsification Cataract Extraction 23 Trabeculotomy by Internal Approach: Trabectome 24 Trabeculotomy by Internal Approach: Dual Blade 25 Gonioscopy-Assisted Transluminal Trabeculotomy 26 Episcleral Venous Fluid Wave: A Snapshot of Patency of the Trabecular Outflow Pathway 27 360-Degree Ab Interno Trabeculotomy 28 Trabecular Bypass: iStent 29 Premium Intraocular Lenses in Minimally Invasive Glaucoma Surgery 30 Trabecular Bypass: Hydrus 31 Excimer Laser Trabeculostomy IIB Uveoscleral Outflow Procedures 32 Canaloplasty 33 Ab Interno Viscodilation of Schlemm's Canal: VISCO 360 and ABiC 34 Suprachoroidal Shunt: SOLX Gold Shunt 35 Ab Interno Suprachoroidal Shunts: CyPass and iStent Supra IIC Aqueous Humor Reduction Procedure 36 Endoscopic Cyclophotocoagulation IID Transconjunctival Filtration Procedures 37 Translimbal Collagen Implant: AqueSys XEN Gel Stent 38 Translimbal SIBS Shunt: InnFocus MicroShunt 39 Combining Minimally Invasive Glaucoma Surgery Procedures 40 Incorporating Minimally Invasive Glaucoma Surgery Procedures Into One's Practice

    2 in stock

    £97.38

  • Thieme Test Prep for the USMLE®: Pathology Q&A

    Thieme Medical Publishers Inc Thieme Test Prep for the USMLE®: Pathology Q&A

    1 in stock

    Book SynopsisThieme Test Prep for the USMLE®: Pathology is the choice of medical students... ...I am very impressed ...These answers and explanations waste no time getting right to the point and hit the high-yield points a student must know... for the USMLE® Step 1 exam. - Nicholas T. Gamboa, MS-II (Second-year medical student, University of Utah School of Medicine) These path questions really tested the concepts succinctly and directly. - Amy Leshner (Fourth-year medical student, Chicago College of Osteopathic Medicine) ...The major test-prep resources do not focus on these subjects in detail. A question bank...would be beneficial to those who struggle with these as an additional resource for studying ... - Ethan Young (Fourth-year medical student, University of South Dakota, Sanford School of Medicine) Thieme Test Prep for the USMLE®: Pathology provides medical students studying for boards with a thorough review of pathology concepts. Co-authored by a pathologist and family practice physician, this robust test prep tool combines pathology with strong clinical correlations. Key Highlights Over 1,100 USMLE®-style multiple choice questions and detailed explanations, classified by organ system and difficulty Questions begin with a clinical vignette and approximately 20% are image-based, mirroring the USMLE®-format This essential resource will help you assess your knowledge and fully prepare for board examinations.Table of Contents1 Cell Injury, Adaptations, and Death 2 Inflammation and Repair 3 Hemodynamics 4 Diseases of the Immune System 5 Neoplasia 6 Genetic and Pediatric Diseases 7 Environmental and Nutritional Diseases 8 Diseases of the Cardiovascular System 9 Diseases of the Hematopoietic and Lymphoid Systems 10 Diseases of the Respiratory System 11 Diseases of the Kidney and Urinary Tract 12 Diseases of the Mouth and Gastrointestinal Tract 13 Diseases of the Liver, Gallbladder, and Biliary Tract 14 Diseases of the Pancreas 15 Diseases of the Male and Female Genital Tract 16 Diseases of the Breast 17 Diseases of the Endocrine System 18 Diseases of the Musculoskeltal System 19 Diseases of the Peripheral and Central Nervous Systems 20 Diseases of the Skin 21 Mixed Items 22 Images

    1 in stock

    £29.55

  • RadCases Plus Q&A Thoracic Imaging

    Thieme Medical Publishers Inc RadCases Plus Q&A Thoracic Imaging

    1 in stock

    Book SynopsisA powerful spectrum of thoracic radiology cases and board-type Q&A review to help you pass your exam! This second edition of RadCases Thoracic Imaging from Carlos Restrepo and Steven Zangan presents 100 differential diagnoses covering the span of lung and thorax disease states, from common conditions such as pneumonia and ARDS to rare conditions like Mounier-Kuhn syndrome and DIPNECH. This edition includes important variations of prior cases, updated diagnostic and management strategies, and new pathological entities. Cases are strategically designed to simulate pathologies encountered in day-to-day practice, increase knowledge, and provide robust exam preparation. For maximum ease of self-assessment, each case begins with the clinical presentation on the right-hand page; study that and then turn the page for CT and chest radiograph findings, differential diagnoses with the definitive diagnosis, essential facts, pearls and pitfalls, and more. Key Features New to this edition, a question-and-answer section for each case reinforces key concepts Nearly 500 high quality figures with clear annotations and descriptions enhance understanding of underlying pathologies Easy-to-read bulleted formatting and concise, point-by-point presentation of the Essential Facts enables learning and retention of high-yield facts and skill-building in thoracic radiologic diagnosis Thieme's RadCases means cases selected to simulate what you will see on your exams, rounds, and rotations. RadCases helps you to identify the correct differential diagnosis for each case, including the most critical. The series comprehensively covers the following specialties: Breast Imaging · Cardiac Imaging · Emergency Imaging · Gastrointestinal Imaging · Genitourinary Imaging · Head and Neck Imaging · Interventional Radiology · Musculoskeletal Radiology · Neuro Imaging · Nuclear Medicine · Pediatric Imaging · Thoracic Imaging · Ultrasound Imaging This RadCases book comes with a code providing access to additional online cases: 100 in this book plus 250+ more cases and interactive Q&A. Master your cases, pass your exams, and diagnose with confidence: RadCases! This print book includes complimentary access to a digital copy on https://medone.thieme.com. Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Master your cases, pass your exams, and diagnose with confidence: RadCases! This print book includes complimentary access to a digital copy on https://medone.thieme.com. Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.Table of Contents100 Radiology Cases

    1 in stock

    £48.45

  • Otolaryngology Lifelong Learning Manual

    Thieme Medical Publishers Inc Otolaryngology Lifelong Learning Manual

    1 in stock

    Book SynopsisOtolaryngology Lifelong Learning Manual, Third Edition is the AAO-HNSF's comprehensive guide for lifelong learning and for those taking certification and re-certification exams in otolaryngology-head and neck surgery. The book is divided into ten sections, each representing a subspecialty within otolaryngology-head and neck surgery, including: General, Facial Plastic and Reconstructive Surgery, Head and Neck, Laryngology and Bronchoesophagology, Otology and Neurotology, Pediatric Otolaryngology, Rhinology and Allergy. Key Features: Focuses on continuing professional development(CPD) and lifelong learning Covers the clinical fundamentals that all otolaryngologists must master Includes a new chapter on trauma written by the AAO-HNSF Trauma Committee which includes active duty military physicians This exam review book is an essential study guide for all residents in otolaryngology preparing for certification exams as well as practicing otolaryngologists preparing to take their re-certification exams.

    1 in stock

    £73.15

  • Lithium: A Doctor, a Drug, and a Breakthrough

    WW Norton & Co Lithium: A Doctor, a Drug, and a Breakthrough

    15 in stock

    Book SynopsisFrom insulin comas and lobotomy to incarceration; those who suffered bipolar disorder endured dangerous, ineffective treatments for centuries until a breakthrough in the 1950s offered salvation. Lithium’s efficacy at both ending and preventing manic depressive episodes was discovered by John Cade, whose years running a psychiatric ward as a prisoner of war sparked a hunch that put him on the path to revelation. The miraculous metal has since salvaged an untold number of lives but even after its healing power was discovered, it was decades before the medical community could be convinced that lithium was not only safe but life-saving. Walter A. Brown reveals how close we came to missing out on this extraordinary drug and showcasing the possibilities of scientific curiosity.Trade Review"The intertwined story of Cade and his momentous finding is told in Lithium, a compelling book by US psychiatrist Walter Brown... What Brown does superbly well is to show that Cade made his discovery without access to advances in technology or to modern facilities — and almost despite them." -- Nature"His [Walter Brown's] beautifully written and insightful book deserves to be widely read by poets and novelists, among whom instances of bipolar disorder are above average, and, more importantly, by all those involved in the regulation and provision of medicines." -- Literary Review

    15 in stock

    £20.89

  • Prepare and Protect: Safer Behaviors in

    American Society for Microbiology Prepare and Protect: Safer Behaviors in

    2 in stock

    Book Synopsis

    2 in stock

    £93.56

  • Color Atlas of Medical Bacteriology

    American Society for Microbiology Color Atlas of Medical Bacteriology

    7 in stock

    Book Synopsis

    7 in stock

    £143.06

  • Metabolomics and Systems Biology in Human Health

    CABI Publishing Metabolomics and Systems Biology in Human Health

    4 in stock

    Book SynopsisThe metabolomics and systems biology approach to research can be applied to many disciplines. This book provides a solid introduction to medical metabolomics and systems biology, and demonstrates how they have been applied to studies in medicine and human health, including nutrition and pathogenic microorganisms. Following core themes of diagnosis, pathology and aetiology of disease, this book provides a reference for health care professionals interested in how to use metabolomics for medical research.Table of Contentsa: Foreword 1: An Introduction to Metabolomics and Systems Biology 2: Metabolomics in Neuroscience and Neurology 3: Cardiovascular Disease and Health 4: Chronic Obstructive Pulmonary Disease (COPD) and Metabolomics 5: In Search of New Biomarkers for Liver Diseases 6: Influences Shaping Digestive Health Explored Using Metabolomics 7: Applications of Metabolomics in the Study of Pathogenic Microorganisms and Their Effects on Human Health 8: Type 2 Diabetes Mellitus and The Metabolic Syndrome 9: Biomarkers of Skeletal Muscle Regulation, Metabolism and Dysfunction 10: Applications of Metabolomics in Cancer Research

    4 in stock

    £88.92

  • Therapeutic Progress in Oncology: Towards a

    ISTE Ltd and John Wiley & Sons Inc Therapeutic Progress in Oncology: Towards a

    Book SynopsisThe combined effects of population growth and aging have led to an increase in the number of cancers. Preventing, diagnosing, treating and curing cancer are therefore, more than ever, imperatives facing medicine – especially to continue the decrease in cancers� mortality rates and to improve the quality of survival. Over time, the �classic� modes of treatment (surgery, external beam radiotherapy, chemotherapy) have become more refined and efficient. From the beginning of this century, new therapeutic options have been developed: targeted cancer therapy, targeted radionuclide therapy and immunologic therapies based on monoclonal antibodies, cellular therapy and vaccinations. Artificial intelligence and machine learning are also being introduced to the field of oncology. Starting with the basic scientific principles relevant to oncology, this book explains and makes these concepts and innovations accessible to a wide audience – especially in the interest of patients. It also contributes to the oncological field of 4P medicine – with 4P standing for predictive, preventive, personalized and participative.Table of ContentsPreface ix Acknowledgments xi Introduction xiii Chapter 1. Genomics and Epigenetics 1 1.1. DNA, RNA and genetic code 1 1.2. Sequencing and genomics 5 1.3. Transcriptome and proteome 10 1.4. Epigenetics, the missing link 13 Chapter 2. Overview of Cancer Chemotherapy 19 2.1. The introduction of an innovative method 20 2.2. Nitrogen mustards, the first revival 21 2.3. Anti-metabolites, the potential for chemotherapy finally revealed 25 2.4. Natural products in the first line 28 2.4.1. Antimitotic agents 28 2.4.2. Topoisomerase inhibitors 30 2.5. Cisplatin and organoplatin derivatives 32 2.6. An evolving therapeutic approach 34 2.6.1. Combinatorial chemotherapy 35 2.6.2. Adjuvant chemotherapy 36 2.7. Targeted therapies 38 Chapter 3. Immunology and the Immune System 41 3.1. From variolation to vaccination 42 3.2. The hegemony of the humoral theory 44 3.2.1. Instructive theory versus selective theory 45 3.2.2. Determining the chemical nature of antibodies 47 3.3. Towards a conciliation between cell theory and humoral theory 48 3.4. A complex and specific mode of action of a so-called adaptive immunity in collaboration with an innate immunity 51 3.4.1. The study of organ transplants for a better understanding of the immune system 51 3.4.2. The predominant role of MHC molecules on T cell reactivity 55 3.4.3. Other membrane molecules with a key role 56 3.4.4. B lymphocytes and antibody production 57 3.4.5. A collaboration with innate immunity 59 3.4.6. Cytokines, immune system messengers 60 3.5. Summary of innate and adaptive immune responses 61 Chapter 4. The Development of Immunotherapy 63 4.1. Immunosuppressive treatments for graft tolerance 63 4.2. Hybridoma techniques for the production of monoclonal antibodies 65 4.3. Towards an understanding of the immune response (anti- and pro-tumor) 68 4.3.1. Demonstration of the influence of the immune system on tumor activity 68 4.3.2. From the theory of immune surveillance to the “3 Es” theory 69 4.3.3. Antitumor factors 70 4.3.4. Protumor factors 71 4.4. Antitumor immunotherapy 72 4.4.1. From Coley toxin to bone marrow and hematopoietic stem cell transplantation 72 4.4.2. From T-cell cultures to antitumor vaccines 74 4.4.3. Monoclonal antibodies: from rituximab to immune checkpoint inhibitors (ICI) 75 4.4.4. Radioimmunotherapy 76 4.5. A promising path tending towards improvement 78 Chapter 5. The Maturation of Artificial Intelligence 79 5.1. From Babbage machines to the universal Turing machine 80 5.2. Cybernetics, for an association between machine and physiology: towards the development of the first neural network 82 5.2.1. Cybernetics… 82 5.2.2. … to connectionism 83 5.2.3. The perceptron, an application of connectionism 84 5.3. Cognitivism and the true emergence of artificial intelligence 86 5.3.1. From the Logic Theorist… 87 5.3.2. …to the LISP Language 88 5.4. From optimism to the first crisis 89 5.4.1. AI in a new momentum 89 5.4.2. Technical and theoretical limits finally revealed 90 5.5. Expert systems, a renewed interest in AI 92 5.6. The return of neural networks: an optimal method of automatic learning? 94 5.6.1. A renewal of the structure and method of learning 94 5.6.2. Different types of machine learning 97 5.6.3. A new wave of hope generated by neural networks and other learning techniques 98 5.7. A new crisis before a decisive rebound 100 5.7.1. A technological context not yet adapted 100 5.7.2. A set of factors at the origin of the Big Data era 101 5.8. Deep learning, an association between Big Data and neural networks: AI in another dimension 103 5.8.1. An evolution of structure and power 103 5.8.2. Convolutional networks, surprising performance 104 5.8.3. A wide range of applications as a trigger for investments 106 5.8.4. AI as an aid to oncology 108 Chapter 6. The Evolution of Cancer Therapy 111 6.1. Cancer surgery 111 6.1.1. Conventional surgery 113 6.1.2. So-called “minimally invasive” surgery 113 6.1.3. Image-guided surgery 114 6.1.4. Cryosurgery 114 6.1.5. Radiofrequency ablation 114 6.1.6. Laser surgery 115 6.1.7. Robotic surgery 115 6.2. External beam radiotherapy (or external beam radiation therapy) 117 6.3. Great innovations in one formula 121 6.4. Genomics and epigenetics 122 6.5. The new therapies of the 21st Century 124 6.5.1. Targeted therapies: the use of small inhibitory molecules (-nib) 125 6.5.2. The use of monoclonal antibodies (mAb) 126 6.5.3. CAR T-cells (Chimeric Antigen Receptor) for customized medicine 128 6.5.4. Vaccine therapies 130 6.5.5. Targeted radionuclide therapy 131 6.6. Theranostics 133 6.6.1. The evolution of medical imaging 133 6.6.2. The theranostic approach, for a predictive and personalized medicine 137 6.7. Artificial intelligence (AI) and Big Data 140 6.8. “In fine” 145 Conclusion 147 List of Abbreviations 161 References 169 Index 177

    £125.06

  • Innovation in Sport: Innovation Trajectories and

    ISTE Ltd and John Wiley & Sons Inc Innovation in Sport: Innovation Trajectories and

    Book SynopsisWhether in terms of practices, equipment or services, the sports sector is characterized by intense inventiveness and is an excellent subject to study innovation processes. This book provides a sociological reading of these processes, illustrated by case studies that allow us to grasp the complexity of innovation trajectories. The case studies highlight the astonishing pathways, from the origin of inventions to their effective dissemination and use, and including the bifurcations of projects. The “surprises” thus presented refer to an invariant of innovation processes, namely that trajectories are rarely linear and that the control exercised over them is relative. Innovation in Sport concludes with a set of recommendations for optimizing the management of sport innovation. This book is intended for students of sports science and management, as well as for professionals and entrepreneurs in the sports markets.Table of ContentsAcknowledgements ix Introduction xi Chapter 1 Theoretical Elements: A Multidisciplinary Framework between Sociology and Management of Innovation 1 1.1 Classical approaches to innovation 2 1.2 Approaches based on uses and users 6 1.2.1 The lead-user theory: the user-innovator 6 1.2.2 Innovation through use: user participation 9 1.2.3 Co-creating value: the consumer at the heart of innovation 10 1.3 The socio-technical approach to innovation: networks and attachment 13 1.4 Critical innovation studies 19 1.5 Lessons learned from resistance to innovation and unsuccessful processes 21 1.6 Conclusion 22 Chapter 2 The Different Phases of Innovation Trajectories 25 2.1 Proposal for an interpretive framework 25 2.2 Breakdown of the methodology 26 2.3 Ideation and invention 32 2.3.1 Innovation program and strategic intent 44 2.3.2 Construction, characterization and evolution of the socio-technical innovation network 50 2.3.3 Key moments in innovation trajectories 59 2.4 Relations with users and the market 64 2.5 Success or failure: assessment of the innovation project and effects on the organizations 72 Chapter 3 Detailed Accounts of Three Sports Innovation Trajectories 83 3.1 The dualski: making downhill skiing accessible to people with disabilities 84 3.1.1 Technical description of the device 84 3.1.2 Ideation: at the intersection of several actors and projects 86 3.1.3 Innovation program: towards the empowerment of disabled people 90 3.1.4 Composition and dynamics of the innovation network surrounding wheelchair skiing 90 3.1.5 Relations with users and the market 100 3.1.6 Conclusion 103 3.2 The Booster Elite calf compression sleeve from BV Sport: innovating to promote recovery and prevent injuries 104 3.2.1 Presentation of the product 104 3.2.2 Ideation phase 106 3.2.3 Innovation program and strategic intent 107 3.2.4 Construction, characterization and evolution of the socio-technical network 108 3.2.5 Key moments in the innovation trajectory 115 3.2.6 Compromises made by BV Sport: between science and market realities 118 3.2.7 Market and user relations 119 3.2.8 Conclusion 124 3.3 Hyperion 7: innovating in the field of video recording sports events 125 3.3.1 The invention phase: the collective emergence of an idea that is less original than adequately problematized 128 3.3.2 The creation of an innovation network focused on the issue of security 131 3.3.3 A network of territorialized actors with its own rules 138 3.3.4 A deliberately delayed step: starting a business 140 3.3.5 The business model envisaged 143 3.3.6 Early and unexpected prospects for diversification 144 3.3.7 A dizzying prospect 147 3.4 Appendices 148 3.4.1 The company Booster Veines Sport (BV Sport) 148 3.4.2 Strategic intent 149 3.5 Sources used 149 3.5.1 Tessier Dualski 149 3.5.2 BV Sport compression sleeve 151 Conclusion: Recommendations for the Management of Sports Organizations 153 References 161 Index 175

    £124.15

  • Constitutional Oncogenetics

    ISTE Ltd Constitutional Oncogenetics

    Book SynopsisIn the age of genomics, oncogenetics is a growing discipline. It is defined as the identification and management of families where there is a suspected hereditary risk of cancer. This relatively new discipline is part of a modern medicine that aims to be both preventive and predictive. Constitutional Oncogenetics gives precise descriptions of the main syndromes that cause a predisposition for cancer. The first part examines the most common syndromes in the majority of the world, including the heightened hereditary risk of breast and ovarian cancer and Lynch syndrome. The second part introduces less common infracentesimal syndromes, such as Bloom syndrome and Fanconi syndrome. This book is intended for oncogenetic practitioners and other specialists, as well as medical students.Table of ContentsForeword xvii Introduction xix Part 1. Major Syndromes 1 Chapter 1. Hereditary Breast and Ovarian Cancer Syndrome Including Isolated Ovarian Cancers 3 1.1. Introduction 3 1.2. Prevalence 4 1.2.1. Genetic risk assessment criteria 5 1.3. Indications for genetic testing 8 1.4. Tumors 8 1.4.1. Breast 8 1.4.2. Ovaries 10 1.5. Genes 12 1.5.1. BRCA1 12 1.5.2. BRCA2 12 1.5.3. CHEK2 12 1.5.4. PALB2 13 1.5.5. NBN 13 1.5.6. BARD1 13 1.5.7. BRIP1 13 1.5.8. RAD51C 14 1.5.9. RAD51D 14 1.6. Genotype–phenotype correlations 14 1.7. Penetrance 15 1.8. Mode of transmission 17 1.9. Risks to family members: special consideration 17 1.10. Monitoring 18 1.10.1. Women 18 1.10.2. Men 20 1.10.3. Men and women 20 1.10.4. Risks to relatives 20 1.10.5. Reproductive options 21 Chapter 2. Lynch Syndrome 25 2.1. Introduction 25 2.2. Prevalence 27 2.3. Genes 28 2.4. Genotype–phenotype correlations 28 2.5. Penetrance and survival 29 2.6. Long-term prevalence of cancer in LS patients 30 2.7. Mode of transmission 33 2.8. When to suspect LS 33 2.8.1. Amsterdam II criteria 33 2.8.2. Criteria to help identify families with LS 33 2.8.3. Revised Bethesda criteria 34 2.8.4. Spectra and syndromes 34 2.9. Tumors 35 2.9.1. Colorectal cancer 35 2.9.2. Endometrial cancer 36 2.9.3. Bladder and urothelial tract 36 2.9.4. Dermatological tumors 37 2.9.5. Pancreatic tumors 38 2.9.6. Tumors of the ovary 38 2.9.7. Brain tumors 38 2.10. Monitoring 39 2.10.1. Colorectal cancer risks 39 2.10.2. GC risks 40 2.10.3. Risks of endometrial and ovarian cancer 40 2.10.4. Risks to the bladder and urothelial tract 41 2.10.5. Risks of dermatological tumors 42 2.10.6. Risks for other types of cancer 42 Chapter 3. Neurofibromatosis 43 3.1. Introduction 43 3.2. Neurofibromatosis type 1 43 3.2.1. Introduction 43 3.2.2. Prevalence 43 3.2.3. When to suspect NF1 44 3.2.4. Tumors 44 3.2.5. Gene 45 3.2.6. Genotype–phenotype correlations 46 3.2.7. Penetrance 46 3.2.8. Mode of transmission 47 3.2.9. Monitoring 48 3.3. Neurofibromatosis type 2 49 3.3.1. Introduction 49 3.3.2. Prevalence 51 3.3.3. When to suspect NF2 51 3.3.4. Tumors 51 3.3.5. Gene 52 3.3.6. Genotype–phenotype correlations 52 3.3.7. Penetrance 53 3.3.8. Mode of transmission 53 3.3.9. Risks to family members 53 3.3.10. Monitoring 54 3.4. Schwannomatosis 55 3.4.1. Introduction 55 3.4.2. Prevalence 55 3.4.3. When to suspect schwannomatosis 55 3.4.4. Tumors 55 3.4.5. Genes 56 3.4.6. Genotype–phenotype correlations 57 3.4.7. Penetrance 57 3.4.8. Mode of transmission 57 3.4.9. Monitoring 58 Chapter 4. Familial Adenomatous Polyposis 59 4.1. Introduction 59 4.1.1. FAP 59 4.1.2. AFAP 60 4.1.3. MAP 60 4.1.4. NAP 60 4.1.5. PPAP 60 4.2. Prevalence 61 4.2.1. FAP 61 4.2.2. MAP 61 4.2.3. NAP 62 4.2.4. PPAP 62 4.3. When to suspect FAP 63 4.4. Tumors 63 4.4.1. FAP 63 4.4.2. MAP 64 4.4.3. NAP 65 4.4.4. PPAP 65 4.5. Genes 65 4.5.1. APC 65 4.5.2. MUTYH 66 4.5.3. NTHL1 66 4.5.4. POLE and POLD1 66 4.6. Genotype–phenotype correlations 67 4.6.1. FAP 67 4.6.2. MAP 67 4.6.3. PPAP 68 4.7. Penetrance 68 4.7.1. FAP 68 4.7.2. MAP 68 4.7.3. PPAP 68 4.8. Mode of transmission 68 4.9. Monitoring 68 4.9.1. FAP 68 4.9.2. Monitoring of extracolonic cancer 69 4.9.3. MAP 70 4.9.4. NAP 70 4.9.5. PPAP 70 Chapter 5. Endocrine Neoplasia 73 5.1. Introduction 73 5.1.1. MEN1 73 5.1.2. MEN2 73 5.1.3. MEN4 74 5.1.4. HPT-JT 74 5.2. Prevalence 75 5.3. When to suspect endocrine neoplasia 75 5.4. Tumors 76 5.4.1. MEN1 76 5.4.2. MEN2 77 5.4.3. MEN4 77 5.4.4. HPT-JT 78 5.5. Genes 78 5.5.1. MEN1 78 5.5.2. RET 78 5.5.3. CDKN1B 79 5.5.4. CDC73 79 5.6. Genotype–phenotype correlations 79 5.6.1. MEN1 79 5.6.2. MEN2 79 5.6.3. MEN4 80 5.6.4. HPT-JT 80 5.7. Penetrance 80 5.7.1. MEN1 80 5.7.2. MEN2 81 5.7.3. MEN4 81 5.7.4. HPT-JT 81 5.8. Mode of transmission 81 5.9. Monitoring 82 5.9.1. MEN1 82 5.9.2. MEN2 83 5.9.3. MEN4 85 5.9.4. HPT-JT 85 Chapter 6. Hereditary Paraganglioma–pheochromocytoma 87 6.1. Introduction 87 6.2. Prevalence 88 6.3. When to suspect a PCC/PGL 88 6.3.1. Pheochromocytomas 88 6.3.2. Paragangliomas 89 6.3.3. Paragangliomas of the head and neck 89 6.3.4. Sympathetic paragangliomas 90 6.4. Tumors 90 6.5. Genes 92 6.5.1. SDHx, SDHAF2 and EPAS1 92 6.5.2. TMEM127 and MAX 93 6.6. Genotype–phenotype correlations 93 6.7. Penetrance 93 6.8. Mode of transmission 95 6.9. Monitoring 95 Chapter 7. Birt–Hogg–Dubé Syndrome 99 7.1. Introduction 99 7.2. Prevalence 99 7.3. When to suspect BHD syndrome 99 7.4. Tumors 100 7.5. Gene 101 7.6. Genotype–phenotype correlations 102 7.7. Penetrance 102 7.8. Mode of transmission 102 7.9. Monitoring 102 Chapter 8. RASopathies 105 8.1. Introduction 105 8.2. Prevalence 105 8.3. When to suspect RASopathies 105 8.4. Tumors 107 8.5. Genes 107 8.6. Genotype–phenotype correlations 108 8.7. Penetrance 108 8.8. Mode of transmission 108 8.9. Monitoring 109 Chapter 9. Familial Malignant Melanoma 111 9.1. Introduction 111 9.2. Prevalence 113 9.3. When to suspect familial malignant melanoma 113 9.4. Tumors 115 9.4.1. CDKN2A 115 9.4.2. BAP1 116 9.4.3. MITF 116 9.4.4. POT1 116 9.5. Genes 116 9.5.1. CDKN2A 116 9.5.2. MITF 117 9.5.3. POT1 117 9.6. Genotype–phenotype correlations 117 9.7. Penetrance 117 9.8. Mode of transmission 118 9.9. Monitoring 118 Chapter 10. Gorlin Syndrome 121 10.1. Introduction 121 10.2. Prevalence 121 10.3. When to suspect GS 121 10.4. Tumors 122 10.5. Genes 123 10.6. Genotype–phenotype correlations 123 10.7. Penetrance 124 10.8. Mode of transmission 124 10.9. Monitoring 124 Part 2. Infracentesimal Syndromes 125 Chapter 11. Li–Fraumeni Syndrome 127 11.1. Introduction 127 11.2. Gene 128 11.3. Tumors 128 11.4. Genetics 129 11.5. Monitoring 130 Chapter 12. Ataxia–telangiectasia 131 12.1. Introduction 131 12.2. Gene 131 12.3. Tumors 132 12.4 Genetics 132 12.5. Monitoring 132 Chapter 13. Hyperparathyroidism 135 13.1. Introduction 135 13.2. Gene 136 13.3. Tumors 136 13.3.1. FIHPT 136 13.3.2. FHH 136 13.3.3. NSHPT 137 13.4. Genetics 137 13.4.1. FIHPT 137 13.4.2. FHH 137 13.4.3. NSHPT 137 13.5. Monitoring 137 Chapter 14. Hamartomatous Polyposis Syndromes 139 14.1. PTEN-hamartoma tumor syndromes 139 14.1.1. Introduction 139 14.1.2. Gene 140 14.1.3. Tumors 140 14.1.4. Genetics 140 14.1.5. Monitoring 141 14.2. Juvenile polyposis syndrome 141 14.2.1. Introduction 141 14.2.2. Gene 142 14.2.3. Tumors 142 14.2.4. Genetics 142 14.2.5. Monitoring 143 14.3. Peutz–Jeghers syndrome 143 14.3.1. Introduction 143 14.3.2. Gene 143 14.3.3. Tumors 144 14.3.4. Genetics 144 14.3.5. Monitoring 145 Chapter 15. Fanconi Syndrome 147 15.1. Introduction 147 15.2. Gene 148 15.3. Tumors 148 15.4. Genetics 148 15.5. Monitoring 149 Chapter 16. Hereditary Diffuse Gastric Cancer 151 16.1. Introduction 151 16.2. Gene 151 16.3. Tumors 152 16.4. Genetics 152 16.5. Monitoring 152 Chapter 17. Von Hippel–Lindau Disease 155 17.1. Introduction 155 17.2. Gene 156 17.3. Tumors 156 17.4. Genetics 158 17.5. Monitoring 158 Chapter 18. Xeroderma Pigmentosum 161 18.1. Introduction 161 18.2. Gene 161 18.3. Tumors 162 18.4. Genetics 162 18.5. Monitoring 162 Chapter 19. Hereditary Papillary Renal Carcinoma 165 19.1. Introduction 165 19.2. Gene 165 19.2.1. MET 165 19.2.2. FH 166 19.3. Tumors 166 19.3.1. HPRC 166 19.3.2. HLRCC 166 19.4. Genetics 167 19.4.1. HPRC type 1 167 19.4.2. HLRCC 168 19.5. Monitoring 168 19.5.1. HPRC 168 19.5.2. HLRCC 168 Chapter 20. Retinoblastoma 171 20.1. Introduction 171 20.2. Gene 171 20.3. Tumors 171 20.4. Genetics 172 20.5. Monitoring 173 20.5.1. Monitoring for intraocular RB 173 20.5.2. Monitoring for trilateral RB 173 20.5.3. Monitoring of second primary tumors 173 Chapter 21. Carney Complex 175 21.1. Introduction 175 21.2. Gene 175 21.3. Tumors 176 21.4. Genetics 176 21.5. Monitoring 177 21.5.1. Screening of prepubescent children 177 21.5.2. Annual screening of children and postpubescent adults 178 Chapter 22. Hematological Malignancies 179 22.1. Introduction 179 22.2. Gene 180 22.3. Tumors 181 22.4. Genetics 182 22.5. Monitoring 182 Chapter 23. Familial Pituitary Adenomas 185 23.1. Introduction 185 23.2. Gene 186 23.3. Tumors 186 23.4. Genetics 187 23.5. Monitoring 187 Chapter 24. Bloom Syndrome 191 24.1. Introduction 191 24.2. Gene 191 24.3. Tumors 192 24.4. Genetics 192 24.5. Monitoring 193 Chapter 25. Werner Syndrome 195 25.1. Introduction 195 25.2. Gene 195 25.3. Tumors 196 25.4. Genetics 196 25.5. Monitoring 197 Appendix: Summary of the Book 199 References 221 Index 245

    £124.15

  • Biology of Archea Volume 1

    ISTE Ltd Biology of Archea Volume 1

    Book SynopsisArchaea constitute a new branch of life alongside bacteria and eukaryotes. These microorganisms are unique in their cellular and molecular aspects. They have evolutionary links with the first eukaryotic cells and are now being used to elucidate fundamental biological questions. Champions of extremophilicity, archaea are helping to lift the veil on the limits of life on Earth. Biology of Archaea 1 explores the discovery and evolution of the field of archaea research. This book also looks at the evolutionary history of archaea and their integration into the tree of life, and examines this complex and extremely diverse world in terms of their ecological niches and their still largely unexplored virosphere.

    £118.80

  • £118.80

  • Interactions between the Geosphere and the

    ISTE Ltd Interactions between the Geosphere and the

    Book SynopsisSince their origins billions of years ago, life on Earth and the planet's surface have undergone profound transformations. Microorganisms inhabiting a primitive planet enveloped by a dioxygen-free atmosphere have evolved into the modern biodiversity under the physico-chemical conditions we know today. In Interactions between the Geosphere and the Biosphere, we characterize the nature and diversity of the close interactions between the biosphere and the geosphere that contributed to the formation and degradation of rocks, on the one hand, and sustained the functioning of ecological systems on the other. The book then explores how these interactions have led to a genuine coevolution between the biosphere and the geosphere over geological time. The most striking manifestations of this are the evolution of the global biogeochemical cycles of carbon and nitrogen, that of climates and the episodes of diversification and extinction of living organisms.

    £118.80

  • South Africa's Gold Mines and the Politics of

    James Currey South Africa's Gold Mines and the Politics of

    10 in stock

    Book SynopsisExamines the silicosis crisis in the South African mining industry, and reveals how the rate of, often fatal, tuberculosis among black migrant miners was hidden for over a century. South Africa's gold mines are the largest and historically among the most profitable in the world. Yet at what human cost? This book reveals how the mining industry, abetted by a minority state, hid a pandemic of silicosis for almost a century and allowed miners infected with tuberculosis to spread disease to rural communities in South Africa and to labour-sending states. In the twentieth century, South African mines twice faced a crisis over silicosis, which put its workers at risk of contracting pulmonary tuberculosis, often fatal. The first crisis, 1896-1912, saw the mining industry invest heavily in reducing dust and South Africa became renowned for its mine safety. The second began in 2000 with mounting scientific evidence that the disease rate among miners is more than a hundred times higher than officially acknowledged. The first crisis also focused upon disease among the minority white miners: the current crisis is about black migrant workers, and is subject to major class actions for compensation. Jock McCulloch was a Legislative Research Specialist for the Australian parliament and has taught at various universities. His books include Asbestos Blues. Southern Africa (South Africa, Namibia, Lesotho, Swaziland & Botswana): JacanaTrade ReviewMakes an important contribution to our understanding of the politics of health, work, science and regulation in southern Africa. The issues it raises are not limited to silicosis nor confined to the apartheid period. * INTERNATIONAL DEVELOPMENT PLANNING REVIEW *Makes a significant contribution to a vibrant literature. [...] A fine book. * SOCIAL HISTORY OF MEDICINE *'a path-breaking book . . . required reading for graduate students in Southern African studies - in fact for anyone seriously interested in the history of the African sub-continent. -- Professor Dunbar MoodieTable of ContentsA Brief Chronology - Preface: South Africa in the twentieth dentury Gold-mining and life-threatening disease Creating a medical system Compensation A White science Myth-making and the 1930 silicosis conference Tropical labour and tuberculosis Conflict over the compensation system Healing miners The sick shall work Men without qualities

    10 in stock

    £23.82

  • Cardiovascular MRI in Practice: A Teaching File Approach

    Springer London Ltd Cardiovascular MRI in Practice: A Teaching File Approach

    1 in stock

    Book SynopsisCardiovascular MR imaging has become a robust, clinically useful mod- ity, and the rapid pace of innovation and important information it conveys have attracted many students whose goal is to become adept practitioners. In turn, many excellent textbooks have been written to aid this process. These books are necessary and useful in helping the student learn the underlying pulse sequences used in CMR, as well as the imaging findings in a variety of disorders. However, one of the difficulties inherent in learning CMR from a book is that the printed format is not the ideal medium to d- play the dynamic imaging that comprises a typical CMR case. For instance, it may be difficult to perceive focal areas of wall motion abnormality on serial static pictures, but these abnormalities are often easily seen on cine loops. One might say that trying to learn CMR solely from a standard textbook with illustrations is like trying to learn to drive by looking at snapshots obtained through the windshield of a moving car. The learner needs to see the cardiac motion and decide if it is normal or abnormal; he or she needs to be in the driver’s seat. An additional limitation of the ava- able textbooks on CMR is that while they often have superb illustrations of abnormal findings, these images have been preselected.Table of ContentsTechniques and Applications.- Overview.- The Standard Cardiac Exam.- Ischemic Heart Disease and Non-Ischemic Cardiomyopathies.- Hemodynamic Assessment and Congenital Heart Disease.- Pericardial Disease and Cardiac Masses.- MR Angiography: General Principles.- Body MRA.- Peripheral MRA.- Cases.- Teaching File Case 1.- Teaching File Case 2.- Teaching File Case 3.- Teaching File Case 4.- Teaching File Case 5.- Teaching File Case 6.- Teaching File Case 7.- Teaching File Case 8.- Teaching File Case 9.- Teaching File Case 10.- Teaching File Case 11.- Teaching File Case 12.- Teaching File Case 13.- Teaching File Case 14.- Teaching File Case 15.- Teaching File Case 16.- Teaching File Case 17.- Teaching File Case 18.- Teaching File Case 19.- Teaching File Case 20.- Teaching File Case 21.- Teaching File Case 22.- Teaching File Case 23.- Teaching File Case 24.- Teaching File Case 25.- Teaching File Case 26.- Teaching File Case 27.- Teaching File Case 28.- Teaching File Case 29.- Teaching File Case 30.- Teaching File Case 31.- Teaching File Case 32.- Teaching File Case 33.- Teaching File Case 34.- Teaching File Case 35.- Teaching File Case 36.- Teaching File Case 37.- Teaching File Case 38.- Teaching File Case 39.- Teaching File Case 40.- Teaching File Case 41.- Teaching File Case 42.- Teaching File Case 43.- Teaching File Case 44.- Teaching File Case 45.- Teaching File Case 46.- Teaching File Case 47.- Teaching File Case 48.- Teaching File Case 49.- Teaching File Case 50.- Teaching File Case 51.- Teaching File Case 52.- Teaching File Case 53.- Teaching File Case 54.- Teaching File Case 55.- Teaching File Case 56.- Teaching File Case 57.- Teaching File Case 58.- Teaching File Case 59.- Teaching File Case 60.- Teaching File Case 61.- Teaching File Case 62.- Teaching File Case 63.- Teaching File Case 64.- Teaching File Case 65.- Teaching File Case 66.- Teaching File Case 67.- Teaching File Case 68.- Teaching File Case 69.- Teaching File Case 70.- Teaching File Case 71.- Teaching File Case 72.- Teaching File Case 73.- Teaching File Case 74.- Teaching File Case 75.- Teaching File Case 76.- Teaching File Case 77.- Teaching File Case 78.- Teaching File Case 79.- Teaching File Case 80.- Teaching File Case 81.- Teaching File Case 82.- Teaching File Case 83.- Teaching File Case 84.- Teaching File Case 85.- Teaching File Case 86.- Teaching File Case 87.- Teaching File Case 88.- Teaching File Case 89.- Teaching File Case 90.- Teaching File Case 91.- Teaching File Case 92.- Teaching File Case 93.- Teaching File Case 94.- Teaching File Case 95.- Teaching File Case 96.- Teaching File Case 97.- Teaching File Case 98.- Teaching File Case 99.- Teaching File Case 100.- Teaching File Case 101.- Teaching File Case 102.- Teaching File Case 103.- Teaching File Case 104.- Teaching File Case 105.- Teaching File Case 106.- Teaching File Case 107.- Teaching File Case 108.- Teaching File Case 109.- Teaching File Case 110.- Teaching File Case 111.- Teaching File Case 112.- Teaching File Case 113.- Teaching File Case 114.- Teaching File Case 115.- Teaching File Case 116.- Teaching File Case 117.- Teaching File Case 118.- Teaching File Case 119.- Teaching File Case 120.- Teaching File Case 121.- Teaching File Case 122.- Teaching File Case 123.- Teaching File Case 124.- Teaching File Case 125.- Teaching File Case 126.- Teaching File Case 127.- Teaching File Case 128.- Teaching File Case 129.- Teaching File Case 130.- Teaching File Case 131.- Teaching File Case 132.- Teaching File Case 133.- Teaching File Case 134.- Teaching File Case 135.- Teaching File Case 136.- Teaching File Case 137.- Teaching File Case 138.- Teaching File Case 139.- Teaching File Case 140.- Teaching File Case 141.- Teaching File Case 142.- Teaching File Case 143.- Teaching File Case 144.- Teaching File Case 145.- Teaching File Case 146.- Teaching File Case 147.- Teaching File Case 148.- Teaching File Case 149.- Teaching File Case 150.

    1 in stock

    £132.99

  • Pocket Primer on the Rheumatic Diseases

    Springer London Ltd Pocket Primer on the Rheumatic Diseases

    15 in stock

    Book SynopsisFor eight decades the Primer on the Rheumatic Diseases has been the standard text from which most medical students and house ofcers have learned rheumatology. I myself will never forget thumbing through an older edition of the Primer as a second-year resident, while waiting to review a perplexing patient with my tutor. Fortunately the tutor was r- ning late with his own patients, so I had time to fip through the book – then much thinner – a couple of times. While turning the pages, per- ing the features of those diseases whose names were still exotic to me, and considering my patient’s history of conductive hearing loss and p- monary nodules, a light went on when I stumbled eventually on a part- ular chapter. I still remember the jaw-dropping efect on my tutor of my announcement then that I had a patient with Wegener’s granulomatosis. I think I became a rheumatologist that very moment! Subsequent editions of the Primer have sufered from the inevitable “obesity creep,” making it an outstanding reference textbook but virtually impossible to fip through quickly while awaiting one’s tutor, and even more difcult to slip into the pocket of a white coat to carry on rounds. For this reason we have created the Pocket Primer, a mini version that cuts the larger book down to its essentials.Table of ContentsHistory and Physical Examination.- Laboratory Assessment.- Arthrocentesis and Synovial Fluid Analysis.- Imaging Techniques.- Monarticular Joint Disease.- Polyarticular Joint Disease.- Regional Rheumatic Pain Syndromes.- Fibromyalgia and Diffuse Pain Syndromes.- Rheumatoid Arthritis.- Juvenile Idiopathic Arthritis.- Psoriatic Arthritis.- Ankylosing Spondylitis.- Reactive and Enteropathic Arthritis.- Osteoarthritis.- Calcium Pyrophosphate Dihydrate, Hydroxyapatite, and Miscellaneous Crystals.- Infectious Disorders.- Systemic Lupus Erythematosus.- Antiphospholipid Syndrome.- Systemic Sclerosis.- Idiopathic Inflammatory Myopathies.- Metabolic Myopathies.- Sjögren’s Syndrome.- Vasculitides.- Behçet’s Syndrome.- Adult Still’s Disease.- Autoinflammatory Disorders/Periodic Syndromes.- Less Common Arthropathies.- Complex Regional Pain Syndrome.- Osteonecrosis.- Paget’S Disease.- Osteoporosis.- Therapeutic Injections.- Nonsteroidal Anti-Inflammatory Drugs.- Glucocorticoids.- Operative Treatment.- Complementary and Alternative Therapies.

    15 in stock

    £47.49

  • Occupational Therapy and Chronic Fatigue Syndrome

    John Wiley & Sons Inc Occupational Therapy and Chronic Fatigue Syndrome

    Book SynopsisWritten for students and clinicians who are new to chronic fatigue syndrome (CFS), this book aims to de-mystify the illness and its management by offering a detailed exploration of the role of the occupational therapist in facilitating the CFS patient?s recovery. Recognising that working with people with CFS involves all aspects of the occupational therapy process, the book demonstrates how many of the skills gained in occupational therapy training and in other area of clinical practice can be transferred to the management of CFS. Case vignettes and more in-depth studies are used throughout to illustrate the syndrome and its management and a full glossary of terms is also included.Table of ContentsSection One. Current Understanding of Chronic Fatigue Syndrome? What is CFS? Definition and Diagnostic Criteria; Aetiology; Clinical Features and Presentation; Prevalence and Prognosis ? The History of CFS. Section Two. The Clinical Management of Chronic Fatigue Syndrome? The Clinical Assessment of CFS? The Pharmacology Management of Chronic Fatigue Syndrome. Section Three. Treatment Approaches in Chronic Fatigue Syndrome? Cognitive Behavioural Therapy; The Development of Behavioural and Cognitive Therapies; The Rationale for the use of CBT with CFS; The Practice of Cognitive Behaviour Therapy ? Graded Exercise: The Rationale for the use of Graded Exercise in CFS; The Practice of Graded Exercise? Occupational Therapy and Lifestyle Management: The Historical Context of Occupational Therapy; the Theoretical Foundations of Occupational Therapy; the Practice of Occupational Therapy.

    £53.15

  • Implementing Research in the Clinical Setting

    John Wiley & Sons Inc Implementing Research in the Clinical Setting

    Book SynopsisThis practical handbook aims to give the practising nurse and health-care professional the tools to implement research in the clinical setting. There is no intention here of revisiting the deep theoretical issues related to research; rather the book seeks to offer a clear toolkit on how the research might be implemented. Chris Bassett has drawn together the work of six acknowledged experts in this field.Trade Review"... this book is very readable..." (Musculoskeletal Care, October 2006)Table of ContentsThe Importance of Research in Nursing Practice. The Relevance of research in Nursing. Commonly-used Research Methods. Reading and Understanding research Reports. Exploring and Overcoming The Barriers to Research. Local and national Context of Research.

    £43.65

  • Clinical Education in Speech-Language Pathology

    John Wiley & Sons Inc Clinical Education in Speech-Language Pathology

    Book SynopsisThis text promotes the view that the clinical education process offers both clinical educators and students opportunities for personal and professional development. It guides the reader through the clinical education process, from pre-placement preparation to assessment of learning that supports and encourages personal and professional development. Included are resources for supporting the clinical education process, such as checklists, case studies and proformas, and vignettes illustrate the richness of students' and clinical educators' learning experiences.Table of ContentsPreface. Chapter 1 Clinical education as professional development for both clinical educators and students. Chapter 2 Preparing for clinical education. Chapter 3 Learning together. Chapter 4 Development of personal skills. Chapter 5 Development of cognitive skills. Chapter 6 Development of learning processes. Chapter 7 The art of learning from assessment. Chapter 8 A continuum of professional development in clinical education. References. Index.

    £43.65

  • Nurse Led Change and Development in Clinical

    John Wiley & Sons Inc Nurse Led Change and Development in Clinical

    Book SynopsisHow may nurses be enabled to contribute to, develop and advance their practice when working in bureaucratic and hierarchical health care settings? Corporate recognition and support for nurse-led change and development is gradually increasing. However, ?top down? change is still frequently imposed without due regard for the wisdom of practitioners. Nurses should explore the theory and practice of change, identify changes to enhance the quality of patient care, and systematically put these into practice. As a result, they will be better equipped to cope with the implementation of national and local policy initiatives, which include shared clinical governance and evidence based nursing practice, both of which are described in this text.This book documents how nurses attempt to undertake change and development in clinical practice through the use of the exploratory, creative, innovative and empowering process of critical action research. The text illustrates the evolution and outcome of the change process. The personal developmental process of engaging in collaborative change in clinical practice is clearly evident. Change is very difficult and complex and if it is to be accomplished successfully it needs to be clearly understood. Consequently, the book also explores the complexity of attempting change in clinical practice. This includes the identification of some of the disempowering processes (both actual and imagined) that currently exist in health care settings.Table of ContentsThe Context for Nurse-led Change and Development. Evolving Clinical change and Action Research. The Integration of Theory and Practice. Preparing for The First Study. The Evolving Critical Action Research Process. The Process and Outcomes of The First Study. The Evolving Critical Action Research Process. The Process and Outcomes of The First Study. Development of The Second Study. Advancing The Change Process. Descriptive Analysis of The Unfreezing Process.. A framework to Advance Change and Development in Clinical Practice. Moving forward.

    £53.15

  • Tics and Tourette Syndrome: Key Clinical

    Mac Keith Press Tics and Tourette Syndrome: Key Clinical

    1 in stock

    Book SynopsisUnlike much of the literature on Tourette syndrome disorders, this book moves away from focusing on the tics and acknowledges that sometimes it is the disorder, such as ADHD, DCD, and OCD, that is the most pressing problem. Roger Freeman, considered a world expert in developmental neurology, shares his vast experience on tic disorders in an informal but highly informative style. He discusses recent advances in the identification and management of tic disorders that many clinicians may be unfamiliar with. Multiple illustrative case histories address many of the mistaken assumptions about tics that are made in everyday clinical practice. Extensive reference lists provide a rich resource for the both the clinician and the researcher. Paediatricians working in neurodisability and child development, child and adolescent psychiatrists and psychologist, neurologists and other health professionals who manage patients with tic disorders will find this book an excellent resource.Table of ContentsContents AUTHOR’S APPOINTMENTS ACKNOWLEDGMENTS CONFLICT OF INTEREST DECLARATION FOREWORD LIST OF ABBREVIATIONS 1 INTRODUCTION 2 DIAGNOSIS AND DEFINITIONS 3 PRESENTATION TO CLINICIANS 4 PREVALENCE AND EPIDEMIOLOGY 5 ETIOLOGY 6 CLINICAL COURSE AND PROGNOSIS 7 PHENOMENOLOGY AND SOCIAL CONSEQUENCES 8 THE LIVED EXPERIENCE 9 FUNCTIONAL (‘CONVERSION DISORDER’ OR ‘PSYCHOGENIC’) TICS 10 COMORBID DISORDERS AND SYMPTOMATOLOGY 11 STEREOTYPIC MOVEMENT DISORDER 12 SYMPTOMS AND PATTERNS 13 TICS IN OTHER MEDICAL CONDITIONS 14 NEUROPSYCHOLOGY 15 INTERVENTIONS AND TREATMENT 16 WORKING WITH SCHOOLS 17 WORKING WITH FAMILIES 18 PEER RELATIONSHIPS AND TEASING/BULLYING 19 CONTROVERSIES 20 REFRACTORY CASES 21 SERVICE PROVISION: A FEW CONSIDERATIONS 22 SUPPORT GROUPS 23 TIC DISORDERS AND THE LAW 24 TOURETTE SYNDROME, EMPLOYMENT AND INSURANCE 25 AND NOW FOR SOMETHING COMPLETELY DIFFERENT 26 SOME PROBLEMS TICS CAN CAUSE FOR OTHERS 27 CODA REFERENCES APPENDIX 1. Then and Now APPENDIX 2. How Accurate is Information on the Internet? APPENDIX 3. Stereotypic Movement Disorder — a Primer for Teachers APPENDIX 4. Comments on the American Practice Parameters on Tic Disorders APPENDIX 5. Stereotypy Severity Scale APPENDIX 6. Web Resources APPENDIX 7. Publications of the TIC Consortium INDEX

    1 in stock

    £57.00

  • Children and Youth with Complex Cerebral Palsy:

    Mac Keith Press Children and Youth with Complex Cerebral Palsy:

    1 in stock

    Book SynopsisChildren with complex cerebral palsy (typically, but not always, GMFCS levels IV and V) require skilled management and extensive expertise which can be overwhelming or intimidating for many clinical practitioners. This book explores management of the many medical comorbidities these children encounter, including orthopedic concerns, mobility and equipment needs, cognition and sensory impairment, difficult behaviors, seizures, respiratory complications and nutritional challenges, among many others. Summary points at the end of each chapter provide at-a-glance access to key recommendations. In addition, an Appendix provides adaptable care tools to guide clinicians in evaluation, preventive care and crisis management. Importantly, the book includes contributions from parents of children with cerebral palsy and youth with cerebral palsy, providing unique and critical wisdom for family-centred care. Parents and families of children and youth with complex cerebral palsy will particularly appreciate the inclusion of chapters on adolescence, transition to adulthood, and growing up, growing well with cerebral palsy.Table of ContentsAuthor Appointments Acknowledgements Preface Opening Quote 1. Overview and Introduction Richard Stevenson and Laurie Glader 2. Functional Assessment and Goals of Management Jilda N Vargus-Adams and Andrea L Paulson 3. Hypertonia Darcy Fehlings, Anne Kawamura, Cecilia Lee and Amber Makino 4. Musculoskeletal/Orthopedic Management Mark J Romness and Victor Anciano 5. Seating, Mobility, and Equipment Needs Christopher D Lunsford and Jonathan Greenwood 6. Osteoporosis and Fractures Steven J Bachrach and Heidi H Kecskemethy 7. Feeding and Nutrition Valentina Intagliata, Eva Delaney and Mary C Bickley 8. Gastrointestinal Issues Beate Beinvogl and Munir Mobassaleh 9. Overview of Pulmonary and Sleep Disorders in Children with Complex Cerebral Palsy Umakanth Katwa and Sebastian K Welsh 10. Speech and Communication John M Costello and Elizabeth N Rose 11. Cognitive and Sensory Impairment Katheryn F Frazier 12.Challenging Behaviors, Sleep and Toileting Alisa Bahl and Kurt A Freeman 13. Mental health in Children and Adolescents with Cerebral Palsy Kerim M Munir and Ikram Rustamov 14. Pain and Irritability Julie Hauer 15. Seizures and Epilepsy in Children with Cerebral Palsy John R Mytinger and Howard P Goodkin 16. Urologic Issues Stuart Bauer 17. Adolescence and Sexuality Susan Hayden Gray 18. Transition to Adulthood Kitty O'Hare and Claudio Melo de Gusmao 19. Evidence Based Care: A Tool Chest for Helping Families Navigate Treatment Options Lisa Samson-Fang 20. Difficult Topics and Decision Making Jim Plews-Ogan and Richard I Grossberg 21. Through the Eyes of Parents Michele Shusterman, Carol Shrader and Jennifer Lyman 22. Growing up, Growing Well with Cerebral Palsy Andrew J Smith, Chelsea Strawser, Benjamin Schrader, Jaylan Norfleet and Garey Noritz Appendix: Care Tools for Clinical Practice

    1 in stock

    £37.95

© 2026 Book Curl

    • American Express
    • Apple Pay
    • Diners Club
    • Discover
    • Google Pay
    • Maestro
    • Mastercard
    • PayPal
    • Shop Pay
    • Union Pay
    • Visa

    Login

    Forgot your password?

    Don't have an account yet?
    Create account